Misawa Hiromi 三澤裕美

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MISAWA Hiromi 三澤裕美

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Researcher Number	50281275
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 教務職員
Affiliation (based on the past Project Information) *help	2013: 奈良県立医科大学, 医学部, 教務職員 2011 – 2013: 奈良県立医科大学, 医学部, その他 2002 – 2010: 奈良県立医科大学, 医学部, 教務職員
Review Section/Research Field	Principal Investigator Digestive surgery / Biomedical engineering/Biological material science Except Principal Investigator Neurophysiology and muscle physiology / Biomedical engineering/Biological material science / Digestive surgery
Keywords	Principal Investigator ３次元培養 / ペプチドゲル / ハンギングドロップ / 腸壁内神経 / セロトニン４受容体 / ES腸管 / 胚性幹細胞 / 心筋細胞内Ca^2+動態 / エナジェティクス / 心筋細胞内Ca^<2+>動態 … More / 心筋スライス / エナジェテクス / 生態情報・計測 / NMR / X線回折実験 / 心筋細胞内カルシウム動態解析 / 心筋スライス標本 … More Except Principal Investigator 蠕動運動 / embryoid body / hanging drop culture / neurofilament / BDNF / 壁内神経系 / 腸管 / 胚性幹細胞 / embryonic stem cell / muscarinic receptor / nicotinic receptor / peristalsis / Ca^<2+> imaging / brain-derived neurotrophic factor / enteric nervous system / pacemaker cell / Caイメージング / ムスカリン受容体 / ニコチン受容体 / カルシウムイメージング / 脳由来神経栄養因子 / ペースメーカ細胞 / ラット / クロスブリッジ / ミオシン / アクチン / 左心室自由壁 / 心臓 / X線回折 / SPring-8 / フィジオーム / 生体システム / 発生分化 / 壁内神経細胞 / ペースメーカー細胞 / 外胚葉 / リアノジン変容体 / embryonic Stem Cell / リアノジン受容体 / T-型Caチャネル / L-型Caチャネル / ペースメーカー電位 / Caオッシレーション / 蠕動様運動 / カハールの間質細胞 Less

Selective neural differentiation method using ES gutPrincipal Investigator
- Principal Investigator
  
  MISAWA Hiromi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nara Medical University
Analysis of myocardial molecular motor dynamics and excitation contraction coupling
- Principal Investigator
  
  JUICHIRO Shimizu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Nara Medical University
Analyses of cardiac energy metabolism and intracellular Ca2+handling in hypertrophic heartsPrincipal Investigator
- Principal Investigator
  
  MISAWA Hiromi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Nara Medical University
Forming control mechanism on pacemaker in the gut differentiated from embryonic stem cells.
- Principal Investigator
  
  TAKAKI Miyako
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Nara Medical University
胚性幹細胞からつくる腸管に壁内神経系をつくる
- Principal Investigator
  
  高木都
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Nara Medical University
胚性幹(ES)細胞から長く伸びる腸管をつくる
- Principal Investigator
  
  TAKAKI Miyako
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Nara Medical University

All 2013 2012 2011 2009 2007 2006

All Journal Article Presentation

[Journal Article] In vivo imaging of enteric neurogenesis in the deep tissue of mouse smallintestine. hearts of SERCA2a transgenic rats.2013
- Author(s)
  Goto K, Obata K, Takaki M, 他
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 1 Pages: e54814-e54814
- DOI
  10.1371/journal.pone.0054814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-23591969, KAKENHI-PROJECT-23700480, KAKENHI-PROJECT-24650325, KAKENHI-PROJECT-25350645, KAKENHI-PROJECT-25460283, KAKENHI-PROJECT-25670177
[Journal Article] Comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anasotomosis in rats.2012
- Author(s)
  Kawahara I. Obata K, Takaki M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 302 Issue: 6 Pages: 588-597
- DOI
  10.1152/ajpgi.00284.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22591491, KAKENHI-PROJECT-22790216, KAKENHI-PROJECT-23390330, KAKENHI-PROJECT-23591969, KAKENHI-PROJECT-24650325
[Journal Article] In vitro morphological bud formation in organ-like three-dimensional structure from mouse ES cells induced by FGF10 signaling2012
- Author(s)
  Ohbuchi, T. Takaki, M. Misawa, H. Suzuki, H. & Ueta, Y
- Journal Title
  
  Communicative & Integrative Biology
  
  Volume: 5(4) Issue: 4 Pages: 1-4
- DOI
  10.4161/cib.20093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390044, KAKENHI-PROJECT-23591969, KAKENHI-PROJECT-24650325
[Journal Article] The comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anasotomosis in rats.2012
- Author(s)
  Kawahara I, Kuniyasu H, Matsuyoshi H, Goto K, Obata K, Misawa H, Fujii H, Takaki M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591969
[Journal Article] Invitro enhanced differentiation of neural networksin ES gut-like organ from mouse ES cells by a 5-HT4-receptor activation.2011
- Author(s)
  Takaki M, Misawa H, Matsuyoshi H, Kawahara I,Goto K, Zhang GX, Obata K, Kuniyasu H
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 406 Issue: 4 Pages: 529-533
- DOI
  10.1016/j.bbrc.2011.02.072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22790216, KAKENHI-PROJECT-23591969
[Journal Article] Increased O2 consumption in excitationcontraction coupling in hypertrophied rat heart slices related to increased Na+-Ca2+ exchange activity.2009
- Author(s)
  Shimizu J, Yamashita D, Misawa H, Tohne K, Matsuoka S, Kim B, Takeuchi A, Nakajima-Takenaka C, Takaki M.
- Journal Title
  
  J Physiol Sci. 59
  
  Pages: 63-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300162
[Journal Article] Inhibition of gut pacemaker cell formation from mouse ES cells by the c-kit inhibitor2007
- Author(s)
  Takaki M, Misawa H, Shimizu J, Kuniyasu H, Horiguchi K
- Journal Title
  
  Biochemical and Biophysical Research Communications 359
  
  Pages: 354-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19700385
[Journal Article] Heart Slice NMR2007
- Author(s)
  Uetani T, Yamashita D, Shimizu J, Misawa H, Tatematsu Y, Hamaguchi Y, Kato T, Katanosaka Y, Miyasaka T, Matsubara T, Furukawa K, Murohara T, Takaki M, Nakayama S
- Journal Title
  
  American Journal of Physiology : Heart and Circulatory Physiology 292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19700385
[Journal Article] In vitro Formation of enteric neural network atructure in a gut-like organ differentiated from mouse embryonic stem cells.2006
- Author(s)
  Takaki M, Nakayama S, Misawa H, Nakagawa T, Kuniyasu H
- Journal Title
  
  Stem Cells 24
  
  Pages: 1414-1422
- Data Source
  KAKENHI-PROJECT-17300130
[Presentation] マウス小腸切離吻合術後の肉芽組織深部に新生した腸壁内神経系のin vivoイメージング法による解析2012
- Author(s)
  後藤桂,加藤剛,川原勲,三澤裕美,石川達也,國安弘基,鍋倉淳一,高木　都
- Organizer
  第40回自律神経生理研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591969
[Presentation] 5-HT4受容体居性化を介したin vitro神経分化促進作用とin vivo神経再生・新生促進作用 (シンポジウム消化器疾患における5-HT受容体を標的にした新たな創薬展開)2012
- Author(s)
  高木都, 三澤裕美, 松吉ひろ子, 川原勲, 後藤桂, 小畑孝二, 國安弘基
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館京都
- Data Source
  KAKENHI-PROJECT-23591969
[Presentation] ES gut-like organ2011
- Author(s)
  Takaki M, Misawa H, Matsuyoshi H, Kuniyasu H.
- Organizer
  An annual meeting of The Korean Society of Smooth Muscle Research in Seoul National University Bundang Hospital
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-23591969
[Presentation] 選択的セロトニン再取り込み阻害薬fluvoxamine(SSRI)のin vitro神経分化,in vivo神経再生・新生作用に対する効果:セロトニン4受容体刺激薬との比較2011
- Author(s)
  高木都, 川原勲, 三澤裕美, 後藤桂, 松吉ひろ子, 小畑孝二, 國安弘基
- Organizer
  第13回日本神経消化器病学会
- Place of Presentation
  栃木総合文化センター栃木
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-23591969

1. TAKAKI Miyako (00033358)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
2. NAKAJIMA Yoshiyuki (00142381)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. NAKAGAWA Tadashi (20372857)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. NAKAYAMA Shinsuke (30192230)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. JUICHIRO Shimizu (80294403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. YAGI Naoto (80133940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KATAOKA Noriyuki (20250681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUYOSHI Hiroko (10448772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. KUNIYASU Hiroki (00253055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 竹中千香子 (50336848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 小畑孝二

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
12. 上田陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Misawa Hiromi 三澤 裕美

MISAWA Hiromi 三澤 裕美

Research Projects

Research Products

Co-Researchers

Selective neural differentiation method using ES gutPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of myocardial molecular motor dynamics and excitation contraction coupling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of cardiac energy metabolism and intracellular Ca2+handling in hypertrophic heartsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Forming control mechanism on pacemaker in the gut differentiated from embryonic stem cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

胚性幹細胞からつくる腸管に壁内神経系をつくる

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

胚性幹(ES)細胞から長く伸びる腸管をつくる

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] In vivo imaging of enteric neurogenesis in the deep tissue of mouse smallintestine. hearts of SERCA2a transgenic rats.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anasotomosis in rats.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vitro morphological bud formation in organ-like three-dimensional structure from mouse ES cells induced by FGF10 signaling2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anasotomosis in rats.2012

Author(s)

Journal Title

Data Source

[Journal Article] Invitro enhanced differentiation of neural networksin ES gut-like organ from mouse ES cells by a 5-HT4-receptor activation.2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased O2 consumption in excitationcontraction coupling in hypertrophied rat heart slices related to increased Na+-Ca2+ exchange activity.2009

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of gut pacemaker cell formation from mouse ES cells by the c-kit inhibitor2007

Author(s)

Journal Title

Data Source

[Journal Article] Heart Slice NMR2007

Author(s)

Journal Title

Data Source

[Journal Article] In vitro Formation of enteric neural network atructure in a gut-like organ differentiated from mouse embryonic stem cells.2006

Author(s)

Journal Title

Misawa Hiromi 三澤裕美

MISAWA Hiromi 三澤裕美