Misawa Hiromi 三澤裕美

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MISAWA Hiromi 三澤裕美

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Researcher Number	50281275
Affiliation (Current)	2023: 奈良県立医科大学, 医学部, 教務職員
Affiliation (based on the past Project Information) *help	2013: 奈良県立医科大学, 医学部, 教務職員 2011 – 2013: 奈良県立医科大学, 医学部, その他 2002 – 2010: 奈良県立医科大学, 医学部, 教務職員
Review Section/Research Field	Principal Investigator Biomedical engineering/Biological material science / Digestive surgery Except Principal Investigator Neurophysiology and muscle physiology / Digestive surgery / Biomedical engineering/Biological material science
Keywords	Principal Investigator 心筋スライス標本 / 心筋細胞内カルシウム動態解析 / X線回折実験 / NMR / 生態情報・計測 / エナジェテクス / 心筋スライス / 心筋細胞内Ca^<2+>動態 / エナジェティクス / 心筋細胞内Ca^2+動態 … More / 胚性幹細胞 / ES腸管 / セロトニン４受容体 / 腸壁内神経 / ハンギングドロップ / ペプチドゲル / ３次元培養 … More Except Principal Investigator embryonic stem cell / 胚性幹細胞 / 腸管 / 壁内神経系 / BDNF / neurofilament / hanging drop culture / embryoid body / 蠕動運動 / カハールの間質細胞 / 蠕動様運動 / Caオッシレーション / ペースメーカー電位 / L-型Caチャネル / T-型Caチャネル / リアノジン受容体 / embryonic Stem Cell / リアノジン変容体 / 外胚葉 / ペースメーカー細胞 / 壁内神経細胞 / 発生分化 / 生体システム / フィジオーム / SPring-8 / X線回折 / 心臓 / 左心室自由壁 / アクチン / ミオシン / クロスブリッジ / ラット / ペースメーカ細胞 / 脳由来神経栄養因子 / カルシウムイメージング / ニコチン受容体 / ムスカリン受容体 / Caイメージング / pacemaker cell / enteric nervous system / brain-derived neurotrophic factor / Ca^<2+> imaging / peristalsis / nicotinic receptor / muscarinic receptor Less

Selective neural differentiation method using ES gutPrincipal Investigator
- Principal Investigator
  
  MISAWA Hiromi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Nara Medical University
Analysis of myocardial molecular motor dynamics and excitation contraction coupling
- Principal Investigator
  
  JUICHIRO Shimizu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Nara Medical University
Analyses of cardiac energy metabolism and intracellular Ca2+handling in hypertrophic heartsPrincipal Investigator
- Principal Investigator
  
  MISAWA Hiromi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Nara Medical University
Forming control mechanism on pacemaker in the gut differentiated from embryonic stem cells.
- Principal Investigator
  
  TAKAKI Miyako
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Nara Medical University
胚性幹細胞からつくる腸管に壁内神経系をつくる
- Principal Investigator
  
  高木都
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Nara Medical University
胚性幹(ES)細胞から長く伸びる腸管をつくる
- Principal Investigator
  
  TAKAKI Miyako
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Digestive surgery
- Research Institution
  Nara Medical University

All 2013 2012 2011 2009 2007 2006

All Journal Article Presentation

[Journal Article] In vivo imaging of enteric neurogenesis in the deep tissue of mouse small intestine.2013
- Author(s)
  Goto K, Obata K, Takaki M, 他
- Journal Title
  
  PLoS One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0054814
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-23591969, KAKENHI-PROJECT-23700480, KAKENHI-PROJECT-24650325, KAKENHI-PROJECT-25350645, KAKENHI-PROJECT-25460283, KAKENHI-PROJECT-25670177
[Journal Article] Comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anasotomosis in rats2012
- Author(s)
  Kawahara I. Obata K, Takaki M
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 302 Pages: 588-597
- DOI
  10.1152/ajpgi.00284.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22591491, KAKENHI-PROJECT-22790216, KAKENHI-PROJECT-23390330, KAKENHI-PROJECT-23591969, KAKENHI-PROJECT-24650325
[Journal Article] In vitro morphological bud formation in organ-like three-dimensional structure from mouse ES cells induced by FGF10 signaling.2012
- Author(s)
  Ohbuchi, T. Takaki, M. Misawa, H. Suzuki, H. & Ueta, Y
- Journal Title
  
  Commun Integr Biol
  
  Volume: 5(4) Pages: 1-4
- DOI
  10.4161/cib.20093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390044, KAKENHI-PROJECT-23591969, KAKENHI-PROJECT-24650325
[Journal Article] The comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anasotomosis in rats.2012
- Author(s)
  Kawahara I, Kuniyasu H, Matsuyoshi H, Goto K, Obata K, Misawa H, Fujii H, Takaki M
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591969
[Journal Article] In vitro enhanced differentiation of neural networks in ES gut-like organ from mouse ES cells by a 5-HT4-receptor activation2011
- Author(s)
  Takaki M, Misawa H, Matsuyoshi H, Kawahara I,Goto K, Zhang GX, Obata K, Kuniyasu H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 406 Pages: 529-33
- DOI
  10.1016/j.bbrc.2011.02.072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500487, KAKENHI-PROJECT-22790216, KAKENHI-PROJECT-23591969
[Journal Article] Increased O2 consumption in excitationcontraction coupling in hypertrophied rat heart slices related to increased Na+-Ca2+ exchange activity.2009
- Author(s)
  Shimizu J, Yamashita D, Misawa H, Tohne K, Matsuoka S, Kim B, Takeuchi A, Nakajima-Takenaka C, Takaki M.
- Journal Title
  
  J Physiol Sci. 59
  
  Pages: 63-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20300162
[Journal Article] Inhibition of gut pacemaker cell formation from mouse ES cells by the c-kit inhibitor2007
- Author(s)
  Takaki M, Misawa H, Shimizu J, Kuniyasu H, Horiguchi K
- Journal Title
  
  Biochemical and Biophysical Research Communications 359
  
  Pages: 354-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19700385
[Journal Article] Heart Slice NMR2007
- Author(s)
  Uetani T, Yamashita D, Shimizu J, Misawa H, Tatematsu Y, Hamaguchi Y, Kato T, Katanosaka Y, Miyasaka T, Matsubara T, Furukawa K, Murohara T, Takaki M, Nakayama S
- Journal Title
  
  American Journal of Physiology : Heart and Circulatory Physiology 292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19700385
[Journal Article] In vitro Formation of enteric neural network atructure in a gut-like organ differentiated from mouse embryonic stem cells.2006
- Author(s)
  Takaki M, Nakayama S, Misawa H, Nakagawa T, Kuniyasu H
- Journal Title
  
  Stem Cells 24
  
  Pages: 1414-1422
- Data Source
  KAKENHI-PROJECT-17300130
[Presentation] マウス小腸切離吻合術後の肉芽組織深部に新生した腸壁内神経系のin vivoイメージング法による解析2012
- Author(s)
  後藤桂,加藤剛,川原勲,三澤裕美,石川達也,國安弘基,鍋倉淳一,高木　都
- Organizer
  第40回自律神経生理研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591969
[Presentation] 5-HT4受容体居性化を介したin vitro神経分化促進作用とin vivo神経再生・新生促進作用 (シンポジウム消化器疾患における5-HT受容体を標的にした新たな創薬展開)2012
- Author(s)
  高木都, 三澤裕美, 松吉ひろ子, 川原勲, 後藤桂, 小畑孝二, 國安弘基
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館京都
- Data Source
  KAKENHI-PROJECT-23591969
[Presentation] ES gut-like organ2011
- Author(s)
  Takaki M, Misawa H, Matsuyoshi H, Kuniyasu H.
- Organizer
  An annual meeting of The Korean Society of Smooth Muscle Research in Seoul National University Bundang Hospital
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-23591969
[Presentation] 選択的セロトニン再取り込み阻害薬fluvoxamine(SSRI)のin vitro神経分化,in vivo神経再生・新生作用に対する効果:セロトニン4受容体刺激薬との比較2011
- Author(s)
  高木都, 川原勲, 三澤裕美, 後藤桂, 松吉ひろ子, 小畑孝二, 國安弘基
- Organizer
  第13回日本神経消化器病学会
- Place of Presentation
  栃木総合文化センター栃木
- Year and Date
  2011-11-05
- Data Source
  KAKENHI-PROJECT-23591969

1. TAKAKI Miyako (00033358)

# of Collaborated Projects: 5 results

# of Collaborated Products: 11 results
2. NAKAJIMA Yoshiyuki (00142381)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. NAKAGAWA Tadashi (20372857)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. NAKAYAMA Shinsuke (30192230)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. JUICHIRO Shimizu (80294403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. YAGI Naoto (80133940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KATAOKA Noriyuki (20250681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUYOSHI Hiroko (10448772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
9. KUNIYASU Hiroki (00253055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 竹中千香子 (50336848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAWAHARA Isao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 小畑孝二

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. 上田陽一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 鍋倉淳一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Misawa Hiromi 三澤 裕美

MISAWA Hiromi 三澤 裕美

Research Projects

Research Products

Co-Researchers

Selective neural differentiation method using ES gutPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of myocardial molecular motor dynamics and excitation contraction coupling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of cardiac energy metabolism and intracellular Ca2+handling in hypertrophic heartsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Forming control mechanism on pacemaker in the gut differentiated from embryonic stem cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

胚性幹細胞からつくる腸管に壁内神経系をつくる

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

胚性幹(ES)細胞から長く伸びる腸管をつくる

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] In vivo imaging of enteric neurogenesis in the deep tissue of mouse small intestine.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anasotomosis in rats2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vitro morphological bud formation in organ-like three-dimensional structure from mouse ES cells induced by FGF10 signaling.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anasotomosis in rats.2012

Author(s)

Journal Title

Data Source

[Journal Article] In vitro enhanced differentiation of neural networks in ES gut-like organ from mouse ES cells by a 5-HT4-receptor activation2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Increased O2 consumption in excitationcontraction coupling in hypertrophied rat heart slices related to increased Na+-Ca2+ exchange activity.2009

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of gut pacemaker cell formation from mouse ES cells by the c-kit inhibitor2007

Author(s)

Journal Title

Data Source

[Journal Article] Heart Slice NMR2007

Author(s)

Journal Title

Data Source

[Journal Article] In vitro Formation of enteric neural network atructure in a gut-like organ differentiated from mouse embryonic stem cells.2006

Author(s)

Journal Title

Misawa Hiromi 三澤裕美

MISAWA Hiromi 三澤裕美