Sakamoto Tohru 坂本透

… Alternative Names

SAKAMOTO Tohru 坂本透

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Researcher Number	50282356
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2019: 筑波大学, 医学医療系, 准教授 2011 – 2015: 筑波大学, 医学医療系, 准教授 2009 – 2010: 筑波大学, 大学院・人間総合科学研究科, 准教授
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine
Keywords	Principal Investigator ゲノムワイド関連解析 / 喘息 / 前向き研究 / 遺伝子多型 / 慢性閉塞性肺疾患 / ゲノム / アレルギー・ぜんそく / 遺伝的リスクスコア / リスクスコア / 一塩基多型 … More / IgE / 遺伝多型 / 肺機能 / COPD / 閉塞性肺疾患 / 肺機能検査 / コホート … More Except Principal Investigator パターン認識受容体 / 自然免疫 / Siglec-8 / マンノース受容体 / 薬理遺伝学 / 組織因子 / フィラグリン / アトピー性皮膚炎 / GWAS / 喫煙 / Nrf2 / TSLP / 呼吸機能 / テーラーメイド / 感受性遺伝子 / COPD / 喘息 Less

Personalized prediction of susceptibility to asthma by genetic risk scorePrincipal Investigator
- Principal Investigator
  
  Sakamoto Tohru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  University of Tsukuba
Comprehensive analysis of risk factors for asthma and COPD by prospective cohort studyPrincipal Investigator
- Principal Investigator
  
  Sakamoto Tohru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  University of Tsukuba
Risk factors for inflammatory obstructive pulmonary diseases: a prospective cohort study.Principal Investigator
- Principal Investigator
  
  SAKAMOTO Tohru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  University of Tsukuba
Study on the pathogenesis of asthma and COPD-genetic heterogeneity and pharmacogenetics-
- Principal Investigator
  
  HIZAWA Nobuyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  University of Tsukuba

All 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

[Book] Advances in Asthma2019
- Author(s)
  Tohru Sakamoto, Nobuyuki Hizawa
- Total Pages
  12
- Publisher
  Springer
- ISBN
  9789811327896
- Data Source
  KAKENHI-PROJECT-17K09603
[Book] COPD2019
- Author(s)
  坂本　透、檜澤伸之
- Total Pages
  360
- Publisher
  中山書店
- ISBN
  9784521745299
- Data Source
  KAKENHI-PROJECT-17K09603
[Journal Article] Effects of Lung Function-Related Genes and TSLP on COPD Phenotypes2020
- Author(s)
  Yamada H, Hida N, Masuko H, Sakamoto T, Hizawa N
- Journal Title
  
  COPD
  
  Volume: 17 Issue: 1 Pages: 59-64
- DOI
  10.1080/15412555.2019.1708296
- NAID
  120007127638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03663, KAKENHI-PROJECT-17K09603
[Journal Article] A cis-eQTL allele regulating reduced expression of CHI3L1 is associated with late-onset adult asthma in Japanese cohorts.2019
- Author(s)
  Kanazawa J, Kitazawa H, Masuko H, Yatagai Y, Sakamoto T, Kaneko Y, Iijima H, Naito T, Saito T, Noguchi E, Konno S, Nishimura M, Hirota T, Tamari M, Hizawa N
- Journal Title
  
  BMC Med Genet
  
  Volume: 20 Issue: 1 Pages: 58-68
- DOI
  10.1186/s12881-019-0786-y
- NAID
  120007127949
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03663, KAKENHI-PROJECT-17K09603, KAKENHI-PROJECT-17K11371, KAKENHI-PROJECT-18K15957
[Journal Article] Association analyses of eQTLs of the TYRO3 gene and allergic diseases in Japanese populations2019
- Author(s)
 Kanazawa J, Masuko H, Yatagai Y, Sakamoto T, Yamada H, Kitazawa H, Iijima H, Naito T, Saito T, Noguchi E, Hirota T, Tamari M, Hizawa N
- Journal Title
 
 Allergol. Int.
 
 Volume: 68 Issue: 1 Pages: 77-81
- DOI
 10.1016/j.alit.2018.07.004
- NAID
 130007557962
- ISSN
 1323-8930, 1440-1592
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PUBLICLY-17H05786, KAKENHI-PROJECT-16K19441, KAKENHI-PROJECT-17K09603
[Journal Article] The Concavity of the Maximal Expiratory Flow?Volume Curve Reflects the Extent of Emphysema in Obstructive Lung Diseases2019
- Author(s)
  Mochizuki Fumi、Iijima Hiroaki、Watanabe Azusa、Tanabe Naoya、Sato Susumu、Shiigai Masanari、Fujiwara Keiji、Shimada Takafumi、Ishikawa Hiroichi、Kanazawa Jun、Yatagai Yohei、Masuko Hironori、Sakamoto Tohru、Muro Shigeo、Hizawa Nobuyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1
- DOI
  10.1038/s41598-019-49591-2
- NAID
  120007132919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09603
[Journal Article] How important is allergic sensitization as a cause of atopic asthma?2018
- Author(s)
  Kanazawa J, Masuko H, Yamada H, Yatagai Y, Sakamoto T, Kitazawa H, Iijima H, Naito T, Hirota T, Tamari M, Hizawa N
- Journal Title
  
  Allergol. Int.
  
  Volume: 67 Issue: 2 Pages: 292-294
- DOI
  10.1016/j.alit.2017.10.005
- NAID
  130006721768
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04827, KAKENHI-PROJECT-17K09603, KAKENHI-PROJECT-16K19441
[Journal Article] Transcription elongation factor P-TEFb is involved in IL-17F signaling in airway smooth muscle cells.2018
- Author(s)
  Nakajima Masayuki, Kawaguchi Mio, Matsuyama Masashi, Ota Kyoko, Fujita Jun, Matsukura Satoshi, Huang Shau-Ku, Morishima Yuko, Ishii Yukio, Satoh Hiroaki, Sakamoto Tohru, Hizawa Nobuyuki.
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 印刷中 Issue: 2 Pages: 83-90
- DOI
  10.1159/000488154
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15454, KAKENHI-PROJECT-15K09209, KAKENHI-PROJECT-17K09603
[Journal Article] Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung2017
- Author(s)
  Kuroda Aoi、Hegab Ahmed E.、Jingtao Gao、Yamashita Shuji、Hizawa Nobuyuki、Sakamoto Tohru、Yamada Hideyasu、Suzuki Satoshi、Ishii Makoto、Namkoong Ho、Asakura Takanori、Ozaki Mari、Yasuda Hiroyuki、Hamamoto Junko、Kagawa Shizuko、Soejima Kenzo、Betsuyaku Tomoko
- Journal Title
  
  Respir Res
  
  Volume: 18 Issue: 1 Pages: 69-69
- DOI
  10.1186/s12931-017-0554-5
- NAID
  120007129115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09603, KAKENHI-PROJECT-15H04827, KAKENHI-PROJECT-16J07163, KAKENHI-PROJECT-15K09229, KAKENHI-PROJECT-15K09580
[Journal Article] IL-17F induces IL-6 via TAK1-NFκB pathway in airway smooth muscle cells2017
- Author(s)
  Masayuki Nakajima, Mio Kawaguchi, Kyoko Ota, Junichi Fujita, Satoshi Matsukura, Shau-Ku Huang, Yuko Morishima, Yukio Ishii, Hiroaki Satoh, Tohru Sakamoto, Nobuyuki Hizawa.
- Journal Title
  
  Immunity, Inflammation and Disease
  
  Volume: 3 Issue: 2 Pages: 1-8
- DOI
  10.1002/iid3.149
- NAID
  120007129102
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09209, KAKENHI-PROJECT-17K09603, KAKENHI-PROJECT-16K15454, KAKENHI-PROJECT-15H04827
[Journal Article] Genetic association of the functional CDHR3 genotype with early-onset adult asthma in Japanese populations2017
- Author(s)
 Kanazawa J, Masuko H, Yatagai Y, Sakamoto T, Yamada H, Kaneko Y, Kitazawa H, Iijima H, Naito T, Saito T, Noguchi E, Konno S, Nishimura M, Hirota T, Tamari M, Hizawa N
- Journal Title
 
 Allergol. Int.
 
 Volume: 66 Issue: 4 Pages: 563-567
- DOI
 10.1016/j.alit.2017.02.012
- NAID
 130006179446
- ISSN
 1323-8930, 1440-1592
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
 KAKENHI-PROJECT-15H04827, KAKENHI-PROJECT-17K09603
[Journal Article] Variants near the HLA complex group 22 gene (HCG22) confer increased susceptibility to late-onset asthma in Japanese populations.2016
- Author(s)
  Yatagai Y, Hirota T, Sakamoto T, Yamada H, Masuko H, Kaneko Y, Iijima H, Naito T, Noguchi E, Tamari M, Kubo M, Takahashi A, Konno S, Makita H, Nishimura M, Hijikata M, Keicho N, Homma S, Taguchi Y, Azuma A, Kudoh S, Hizawa N.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 印刷中 Issue: 1 Pages: 281-283
- DOI
  10.1016/j.jaci.2015.11.023
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461147, KAKENHI-PROJECT-24390251, KAKENHI-PROJECT-15H04827
[Journal Article] 喘息COPDオーバーラッップ症候群（ACOS）2016
- Author(s)
  坂本　透
- Journal Title
  
  別冊　日本臨床　免疫症候群（第2版）
  
  Volume: 別冊 Pages: 172-175
- Data Source
  KAKENHI-PROJECT-25461147
[Journal Article] FACTORS ASSOCIATED WITH THE PRESENCE OF ALLERGEN-SPECIFIC IgE RESPONSES IN ASTHMA PATIENTS WHO HAD NO IgE RESPONSES DETECTABLE BY MAST-262015
- Author(s)
  Iijima H, Kaneko Y, Masuko H, Yamada H, Yatagai Y, Sakamoto T, Kanemoto K, Ishikawa H, Saito T, Endo T, Ninomiya H, Nomura A, Kodama T, Kaneko N, Kokubu F, Makita H, Konno S, Nishimura M, Hizawa N
- Journal Title
  
  Japanese Journal of Allergology
  
  Volume: 64 Issue: 9 Pages: 1242-1253
- DOI
  10.15036/arerugi.64.1242
- NAID
  130005130144
- ISSN
  0021-4884, 1347-7935
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461147
[Journal Article] Role of Lung Function Genes in the Development of Asthma2015
- Author(s)
  Yamada H, Masuko H, Yatagai Y, Sakamoto T, Kaneko Y, Iijima H, Naito T, Noguchi E, Konno S, Nishimura M, Hirota T, Tamari M, Hizawa N
- Journal Title
  
  PLoS One
  
  Volume: － Issue: 1 Pages: e0145832-e0145832
- DOI
  10.1371/journal.pone.0145832
- NAID
  120007129828
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04827, KAKENHI-PROJECT-25461147, KAKENHI-PROJECT-24390251
[Journal Article] 喫煙・ニコチン依存症の遺伝子機構とその対策2015
- Author(s)
  坂本　透、檜澤伸之
- Journal Title
  
  呼吸器内科
  
  Volume: 27 Pages: 236-240
- NAID
  40020404868
- Data Source
  KAKENHI-PROJECT-25461147
[Journal Article] Heritability of pulmonary function estimated from genome-wide SNPs in healthy Japanese adults.2015
- Author(s)
  Yamada H, Yatagai Y, Masuko H, Sakamoto T, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Hizawa N
- Journal Title
  
  Respir Investig
  
  Volume: 53 Issue: 2 Pages: 60-67
- DOI
  10.1016/j.resinv.2014.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390206, KAKENHI-PROJECT-24659400, KAKENHI-PROJECT-25461147
[Journal Article] Genomewide association study identifies HAS2 as a novel susceptibility gene for adult asthma in a Japanese population2014
- Author(s)
  Yatagai Y, Sakamoto T, Yamada H, Masuko H, Kaneko Y, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Konno S, Nishimura M, Hizawa N
- Journal Title
  
  Clin Exp Allergy
  
  Volume: 44 Issue: 11 Pages: 1327-1334
- DOI
  10.1111/cea.12415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390206, KAKENHI-PROJECT-24390251, KAKENHI-PROJECT-24659400, KAKENHI-PROJECT-25461147
[Journal Article] Influence of MILR1 promoter polymorphism on expression levels and the phenotype of atopy.2014
- Author(s)
  Nanatsue K, Ninomiya T, Tsuchiya M, Tahara-Hanaoka S, Shibuya A, Masuko H, Sakamoto T, Hizawa N, Arinami T, Noguchi E.
- Journal Title
  
  J Hum Genet
  
  Volume: 59(9) Issue: 9 Pages: 480-483
- DOI
  10.1038/jhg.2014.57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249021, KAKENHI-PROJECT-24390205, KAKENHI-PROJECT-24390206, KAKENHI-PROJECT-24390251, KAKENHI-PROJECT-24659400, KAKENHI-PROJECT-25461147
[Journal Article] アレルゲン特異的IgE反応性から分類した喘息フェノタイプ―Thymic stromal lymphopoietin（TSLP）遺伝子と喫煙の役割―2014
- Author(s)
  飯島弘晃, 山田英恵, 谷田貝洋平, 金子美子, 内藤隆志, 坂本　透, 増子裕典, 広田朝光, 玉利真由美, 今野　哲, 西村正治, 檜澤伸之
- Journal Title
  
  アレルギー
  
  Volume: 63 Pages: 33-44
- NAID
  110009798511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461147
[Journal Article] The effects of a Gly16Arg ADRB2 polymorphism on responses to salmeterol or montelukast in Japanese patients with mild persistent asthma2014
- Author(s)
  Konno S, Hizawa N, Makita H, Shimizu K, Sakamoto T, Kokubu F, Saito T, Endo T, Ninomiya H, Iijima H, Kaneko N, Ito YM, Nishimura M
- Journal Title
  
  Pharmacogenet Genomics
  
  Volume: 24 Issue: 5 Pages: 246-255
- DOI
  10.1097/fpc.0000000000000043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390206, KAKENHI-PROJECT-24659400, KAKENHI-PROJECT-25461147
[Journal Article] Asthma Phenotypes in Japanese Adults - Their Associations with the CCL5 and ADRB2 Genotypes2013
- Author(s)
 Kaneko Y
- Journal Title
 
 Allergol. Int.
 
 Volume: 62 Issue: 1 Pages: 113-121
- DOI
 10.2332/allergolint.12-OA-0467
- NAID
 130004477174
- ISSN
 1323-8930, 1440-1592
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22591151, KAKENHI-PROJECT-24390251, KAKENHI-PROJECT-25461147
[Journal Article] A distinct sensitization pattern associated with asthma and the thymic stromal lymphopoietin (TSLP) genotype2013
- Author(s)
  Iijima H, Kaneko Y, Yamada H, Yatagai Y, Masuko H, Sakamoto T, Nai t o T, Hirota T, Tamari M, Konno S, Nishimura M, Noguchi E, Hizawa N.
- Journal Title
  
  Allergol Int.
  
  Volume: 62(1) Pages: 123-30
- NAID
  130004477178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] The search for common pathways underlying asthma and COPD2013
- Author(s)
  Kaneko Y, Yatagai Y, Yamada H, Iijima H, Masuko H, Sakamoto T, Hizawa N
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis
  
  Volume: 8 Pages: 65-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] A Distinct Sensitization Pattern Associated with Asthma and the Thymic Stromal Lymphopoietin (TSLP) Genotype2013
- Author(s)
 Iijima H
- Journal Title
 
 Allergol. Int.
 
 Volume: 62 Issue: 1 Pages: 123-130
- DOI
 10.2332/allergolint.12-OA-0488
- NAID
 130004477178
- ISSN
 1323-8930, 1440-1592
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-22591151, KAKENHI-PROJECT-24390251, KAKENHI-PROJECT-25461147
[Journal Article] COPDと遺伝素因2013
- Author(s)
  坂本　透、檜澤伸之
- Journal Title
  
  Modern Physician
  
  Volume: 33 Pages: 1359-1361
- Data Source
  KAKENHI-PROJECT-25461147
[Journal Article] The search for common pathways underlying asthma and COPD2013
- Author(s)
  Kaneko Y, Yatagai Y, Yamada H, Iijima H, Masuko H, Sakamoto T, Hizawa N
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis
  
  Volume: 8 Pages: 65-78
- DOI
  10.2147/copd.s39617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390206, KAKENHI-PROJECT-24659400, KAKENHI-PROJECT-25461147
[Journal Article] 喘息とのオーバーラップ症候群2013
- Author(s)
  坂本　透
- Journal Title
  
  呼吸器内科
  
  Volume: 24 Pages: 526-529
- Data Source
  KAKENHI-PROJECT-25461147
[Journal Article] Genome-wide association study for levels of total serum IgE identifies HLA-C in a Japanese population2013
- Author(s)
  Yatagai Y, Sakamoto T, Masuko H, et al
- Journal Title
  
  PLoS One
  
  Volume: 8(12) Issue: 12 Pages: 1-9
- DOI
  10.1371/journal.pone.0080941
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390397, KAKENHI-PROJECT-24390206, KAKENHI-PROJECT-24390251, KAKENHI-PROJECT-24659400, KAKENHI-PROJECT-24791761, KAKENHI-PROJECT-25293348, KAKENHI-PROJECT-25461147
[Journal Article] Asthma phenotypes in Japanese adults - their associations with the CCL5 and ADRB2 genotypes2013
- Author(s)
  Kaneko Y, Masuko H, Sakamoto T, Iijima H, Naito T, Yatagai Y, Yamada H, Konno S, Nishimura M, Noguchi E, Hizawa N
- Journal Title
  
  Allergol Int
  
  Volume: 62(1) Pages: 113-21
- NAID
  130004477174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] The opposite effect of the CCL5 gene on asthma and baseline FEV(1) in nonasthmatic healthy adults2012
- Author(s)
  Kaneko Y, Masuko H, Sakamoto T, Iijima H, Naito T, Hizawa N
- Journal Title
  
  Allergol Int
  
  Volume: 61(1) Pages: 177-8
- NAID
  130004873037
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] COPDと喘息　オーバーラップ症候群の治療はどうするべきか2012
- Author(s)
  坂本　透
- Journal Title
  
  Medicina
  
  Volume: 49 Pages: 474-6
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population2012
- Author(s)
  Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Sakashita M, Yamada T, Fujieda S, Tanaka S, Doi S, Miyatake A, Enomoto T, Nishiyama C, Nakano N, Maeda K, Okumura K, Ogawa H, Ikeda S, Noguchi E, Sakamoto T, Hizawa N, Ebe K, Saeki H, Sasaki T, Ebihara T
- Journal Title
  
  Nat Genet
  
  Volume: 44(11) Pages: 1222-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma2011
- Author(s)
  Harada M, Hirota T, Jodo AI, Hitomi Y, Sakashita M, Tsunoda T, Miyagawa T, Doi S, Kameda M, Fujita K, Miyatake A, Enomoto T, Noguchi E, Masuko H, Sakamoto T, Hizawa N, Suzuki Y, Yoshihara S, Adachi M, Ebisawa M, Saito H, Matsumoto K, Nakajima T, Mathias
- Journal Title
  
  Am JRespir Cell Mol Biol
  
  Volume: 44(6) Pages: 787-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] Variants of C-C Motif Chemokine 22 (CCL22) Are Associated with Susceptibility to Atopic Dermatitis: Case-Control Studies2011
- Author(s)
  Hirota T, Saeki H, Tomita K, Tanaka S, Ebe K, Sakashita M, Yamada T, Fujieda S, Miyatake A, Doi S, Enomoto T, Hizawa N, Sakamoto T, Masuko H, Sasaki T, Ebihara T, Amagai M, Esaki H, Takeuchi S, Furue M, Noguchi E, Kamatani N, Nakamura Y, Kubo M, Tamari
- Journal Title
  
  PLoS One
  
  Volume: 6(11)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations2011
- Author(s)
  Noguchi E, Sakamoto H, Hirota T, Ochiai K, Imoto Y, Sakashita M, Kurosaka F, Akasawa A, Yoshihara S,Kanno N, Yamada Y, Shimojo N, Kohno Y, Suzuki Y, Kang MJ, Kwon JW, Hong SJ, Inoue K, Goto Y, Yamashita F, Asada T, Hirose H, Saito I, Fujieda S, Hizawa N
- Journal Title
  
  PLoS Genet
  
  Volume: 7(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] Lower FEV1 in non-COPD, nonasthmatic subjects: association with smoking, annual decline in FEV1, total IgE levels, and TSLP genotypes2011
- Author(s)
  Masuko H, Sakamoto T, Kaneko Y, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Hizawa N
- Journal Title
  
  Int J Chron Obstruct Pulmon Dis
  
  Volume: 6 Pages: 181-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] An interaction between Nrf2 polymorphisms and smoking status affects annual decline in FEV1 : a longitudinal retrospective cohort study2011
- Author(s)
  Masuko H, Sakamoto T, Naito T, Noguchi E, Hirota T, Tamari M, Hizawa N
- Journal Title
  
  BMC Med Genet
  
  Volume: 12 Pages: 97-97
- NAID
  120007137552
- Data Source
  KAKENHI-PROJECT-21390254
[Journal Article] Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population2011
- Author(s)
  Hirota T, Sakamoto T, Hizawa N, Tamari M
- Journal Title
  
  Nat Genet
  
  Volume: 43(9) Pages: 893-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390254
[Journal Article] Thymic stromal lymphopoietin gene promoter polymorphisms are associated with susceptibility to bronchial asthma2011
- Author(s)
  Harada M, Hirota T, Noguchi E, Sakamoto T, Hizawa N, Mathias RA, Rafaels N, Barnes KC, Himes BE, Duan QL, Tantisira KG, Weiss ST, Nakamura Y, Ziegler SF, Tamari M
- Journal Title
  
  Am J Respir Cell Mol Biol
  
  Volume: 44(6) Pages: 787-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390254
[Journal Article] Lower FEV1 in non-COPD, nonasthmatic subjects : association with smoking, annual decline in FEV1, total IgE levels, and TSLP genotypes2011
- Author(s)
  Masuko H, Sakamoto T, Noguchi E, Hirota T, Tamari M, Hizawa N
- Journal Title
  
  Int J Chron Obstruct Pulm Dis
  
  Volume: 6 Pages: 181-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390254
[Journal Article] Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population2011
- Author(s)
  Hirota T, Takahashi A, Kubo M, Tsunoda T, Tomita K, Doi S, Fujita K, Miyatake A, Enomoto T, Miyagawa T, Adachi M, Tanaka H, Niimi A, Matsumoto H, Ito I, Masuko H, Sakamoto T, Hizawa N, Taniguchi M, Lima JJ, Irvin CG, Peters SP, Himes BE, Litonjua AA, Ta
- Journal Title
  
  Nat Genet
  
  Volume: 43(9) Pages: 893-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] Variants of C-C motif chemokine 22 (CCL22) are associated with susceptibility to atopic dermatitis : case-control studies2011
- Author(s)
  Hirota T, Saeki H, Tomita K, Hizawa N, Sakamoto T, Masuko H, Sasaki T, Ebihara T, Amagai M, Esaki H, Takeuchi S, Furue M, Noguchi E, Kamatani N, Nakamura Y, Kubo M, Tamari M
- Journal Title
  
  PLoS One
  
  Volume: 6(11)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390254
[Journal Article] Blockade of cysteinyl leukotriene-1 receptors suppresses airway remodelling in mice overexpressing GATA-32011
- Author(s)
  Kiwamoto T, Ishii Y, Morishima Y, Yoh K, Kikuchi N, Haraguchi N, Masuko H, Kawaguchi M, Nomura A, Sakamoto T, Takahashi S, Hizawa N
- Journal Title
  
  Clin Exp Allergy
  
  Volume: 41(1) Pages: 116-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390254
[Journal Article] COPD疾患感受性遺伝子2011
- Author(s)
  坂本透、檜澤伸之
- Journal Title
  
  日本臨床
  
  Volume: 69(10) Pages: 1758-62
- Data Source
  KAKENHI-PROJECT-22590834
[Journal Article] Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations2011
- Author(s)
  Noguchi E, Sakamoto H, Hirota T, Ochiai K, Kohno Y, Kang MJ, Kwon JW, Hong SJ, Inoue K, Goto Y, Yamashita F, Asada T, Hirose H, Saito I, Fujieda S, Hizawa N, Sakamoto T, Masuko H, Nakamura Y, Nomura I, Tamari M, Arinami T, Yoshida T, Saito H, Matsumoto K
- Journal Title
  
  PLoS Genet
  
  Volume: 7(7)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390254
[Journal Article] COPD疾患感受性遺伝子特集:COPDII.COPD発症の病因・危険因子2011
- Author(s)
  坂本透, 檜澤伸之
- Journal Title
  
  日本臨床
  
  Volume: 69(10) Pages: 1758-1762
- Data Source
  KAKENHI-PROJECT-21390254
[Journal Article] An interaction between Nrf2 polymorphisms and smoking status affects annual decline in FEV1: a longitudinal retrospective cohort study.2011
- Author(s)
  Masuko H, Sakamoto T, Kaneko Y, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Hizawa N
- Journal Title
  
  BMC Med Genet
  
  Volume: 12 Pages: 97-97
- NAID
  120007137552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 閉塞性肺疾患におけるflow-volume曲線の視覚的評価と胸部CTの定量評価に関する検討2019
- Author(s)
  望月芙美、飯島弘晃、嶋田貴文、藤原啓司、石川博一、増子裕典、坂本　透、田辺直也、佐藤　晋、室　繁郎、檜澤伸之
- Organizer
  第59回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] アレルギー感作感受性遺伝子群がCDHR3およびTYRO3遺伝子の効果に与える影響2019
- Author(s)
  金澤　潤、増子裕典、北沢晴奈、谷田貝洋平、飯島弘晃、内藤隆志、広田朝光、玉利真由美、坂本　透、檜澤伸之
- Organizer
  第59回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] 慢性炎症性肺疾患における増悪関連フェノタイプの検討2019
- Author(s)
  兵頭健太郎、増子裕典、重政理恵、北沢晴奈、金澤　潤、谷田貝洋平、飯島弘晃、児玉孝秀、野村明広、籠橋克紀、佐藤浩昭、坂本　透、齋藤武文、檜澤伸之
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] 重症喘息に対するペンラリズマブ治療早期の有効性の検討2019
- Author(s)
  中嶋真之、松山政史、川口未央、荒井直樹、北沢晴奈、吉田和史、兵頭健太郎、金澤　潤、山田英恵、増子裕典、際本拓未、森島祐子、石井幸雄、坂本　透、齋藤武文、檜澤伸之
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] 呼吸機能関連遺伝子及びTSLP遺伝子がCOPDフェノタイプに与える影響2019
- Author(s)
  山田英恵、肥田憲人、増子裕典、坂本　透、檜澤伸之
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] Genetic effects of ORMDL3/GSDMB on asthma are modified by the GSDMC genotype at chromosome 8.2019
- Author(s)
  Kitazawa H, Masuko H, Kanazawa J, Shigemasa R, Hyodo K, Yatagai Y, Iijima H, Naito T, Saito T, Hirota T, Tamari M, Sakamoto T, Hizawa N.
- Organizer
  American Thoracic Society Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] BMI、IL6、高感度CRPに関する遺伝要因と喘息との関連2019
- Author(s)
  北沢晴奈、増子裕典、金澤　潤、谷田貝洋平、飯島弘晃、内藤隆志、広田朝光、玉利真由美、坂本　透、檜澤伸之
- Organizer
  第59回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] A cis-eQTL allele lowering gene expression of CHL3L1 is associated with late-onset adult asthma in Japanese.2019
- Author(s)
  Shigemasa R, Kanazawa J, Kitazawa H, Masuko H, Hyodo K, Yatagai Y, Sakamoto T, Kaneko Y, Iijima H, Naito T, Saito T, Noguchi E, Konno S, Nishimura M, Hirota T, Tamari M, Hizawa N.
- Organizer
  American Thoracic Society Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] 原発性繊毛機能不全症に関連する遺伝子群が喘息に与える影響について2019
- Author(s)
  重政理恵、増子裕典、金澤　潤、北沢晴奈、兵頭健太郎、谷田貝洋平、飯島弘晃、内藤隆志、坂本　透、広田朝光、玉利真由美、檜澤伸之
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] 中高年喫煙者における呼気一酸化窒素濃度に影響を与える因子について2019
- Author(s)
  金澤　潤、増子裕典、重政理恵、兵頭健太郎、北沢晴奈、谷田貝洋平、飯島弘晃、坂本透、家城隆次、檜澤伸之
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] ORMDL3/GSDMB遺伝子が喘息に与える影響はGSDMC遺伝子多型によって異なる2019
- Author(s)
  北沢晴奈、増子裕典、金澤　潤、重政理恵、兵頭健太郎、谷田貝洋平、飯島弘晃、内藤隆志、広田朝光、玉利真由美、坂本　透、檜澤伸之
- Organizer
  第68回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] アレルギー感作関連遺伝子が成人喘息に与える影響2018
- Author(s)
  金澤　潤、増子裕典、山田英恵、谷田貝洋平、北沢晴奈、飯島弘晃、内藤隆志、広田朝光、玉利真由美、坂本　透、檜澤伸之
- Organizer
  第67回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] TYRO3: A Gene for Allergic Rhinitis?2018
- Author(s)
  Kanazawa J, Masuko H, Yatagai Y, Yamada H, Sakamoto T, Kitazawa H, Iijima H, Naito T, HIrota M, Tamari M, Hizawa N.
- Organizer
  American Thoracic Society Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] IL-17FによるIL-6、IL-8産生に対するステロイドとLABAの効果2018
- Author(s)
  中嶋真之、川口未央、太田恭子、藤田純一、松山政史、松倉　聡、塩澤利博、中澤健介、増子裕典、際本拓未、松野洋輔、森島祐子、佐藤浩昭、坂本　透、檜澤伸之
- Organizer
  第58回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] CHI3L1遺伝子eQTLが喘息に与える影響2018
- Author(s)
  金澤　潤、増子裕典、谷田貝洋平、飯島弘晃、内藤隆志、齋藤武文、野口恵美子、今野　哲、西村正治、広田朝光、玉利真由美、坂本　透、檜澤伸之
- Organizer
  第58回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] How important is allergic sensitization as a cause of atopic asthma?2018
- Author(s)
  Yatagai Y, Kanazawa J, Masuko H, Yamada H, Sakamoto T, Kitazawa H, Iijima H, Naito T, Hirota T, Tamari M, Hizawa N.
- Organizer
  American Thoracic Society Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] Effect of steroids and long-acting-beta agonist on IL-17F induced IL-6 and IL-8 expression2018
- Author(s)
  Nakajima M, Kawaguchi M, Mastuyama M, Yoshida K, Ota K, Fujita J, Matsukura S, Huang S-K, Morishima Y, Ishii Y, Satoh H, Sakamoto T, Hizawa N.
- Organizer
  American Thoracic Society Conference 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] 気道平滑筋細胞におけるIL-6、IL-8産生に対するIL17FとLABAの増強効果2018
- Author(s)
  中嶋真之、川口未央、太田恭子、藤田純一、松山政史、松倉　聡、塩澤利博、中澤健介、増子裕典、際本拓未、松野洋輔、森島祐子、佐藤浩昭、坂本　透、檜澤伸之
- Organizer
  第67回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] 気道平滑筋細胞におけるIL-17FからのIL-6発現と分子機構2017
- Author(s)
  中嶋真之、太田恭子、藤田純一、川口未央、松倉　聡、増子裕典、際本拓未、松野洋輔、森島祐子、佐藤浩昭、坂本　透、檜澤伸之
- Organizer
  第66回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] 日本人集団におけるCDHR3遺伝子多型が若年発症瑞息に与える影響2017
- Author(s)
  金澤　潤、増子裕典、北沢晴奈、山田英恵、谷田貝洋平、金子美子、飯島弘晃、内藤隆志、齋藤武文、今野　哲、西村正治、広田朝光、玉利真由美、坂本　透、檜澤伸之
- Organizer
  第57回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] Role of the CDHR3 Variant (Cys529→Tyr) in Early-Onset Adult Asthma in Japanese Populations.2017
- Author(s)
  Kanazawa J, Masuko H, Kitazawa H, Yamada Y, Yatagai Y, Kaneko Y, Iijima H, Naito T, Saito T, Noguchi E, Konno S, Nishimura M, Hirota T, Tamari M, Sakamoto T, Hizawa N.
- Organizer
  American Thoracic Society Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] 喘息患者における血清高感度CRPの検討2017
- Author(s)
  北沢晴奈、増子裕典、金澤　潤、谷田貝洋平、金子美子、飯島弘晃、内藤隆志、坂本　透、檜澤伸之
- Organizer
  第66回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] 日本人集団におけるTYRO3遺伝子多型がアレルギー疾患に与える影響2017
- Author(s)
  金澤　潤、増子裕典、北沢晴奈、谷田貝洋平、飯島弘晃、内藤隆志、野口佳子、広田朝光、玉利真由美、坂本　透、檜澤伸之
- Organizer
  第66回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] IL-17F Induces IL-6 Via TAK1-NFbkB Pathway in Airway Smooth Muscle Cells.2017
- Author(s)
  Nakajima M, Kawaguchi M, Ota K, Fujita J, Matsukura S, Huang SK, Masuko H, Kiwamoto T, Matsuno Y, Morishima Y, Ishii Y, Satoh H, Sakamoto T, Hizawa N.
- Organizer
  American Thoracic Society Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] IL-17Fによる気道平滑筋細胞からのIL-6発現とその分子機構2017
- Author(s)
  中嶋真之、太田恭子、藤田純一、川口未央、松倉　聡、塩澤利博、中澤健介、増子裕典、際本拓未、松野洋輔、森島祐子、佐藤浩昭、坂本　透、檜澤伸之
- Organizer
  第57回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-17K09603
[Presentation] Genome-wide association study for late-onset asthma demonstrates possible association with a gene related to diffuse panbronchiolitis2015
- Author(s)
  Yatagai Y, Sakamoto T, Ymada H, Masuko H, Kaneko Y, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Makita H, Konno S, Nishimura M, Hizawa N.
- Organizer
  American Thoracic Society 2015 International Conference
- Place of Presentation
  Colorado Convention Center (Denver)
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 呼吸機能関連遺伝子による喘息病態の検討2015
- Author(s)
  山田英恵、谷田貝洋平、増子裕典、坂本　透、飯島弘晃、内藤隆志、野口恵美子、広田朝光、玉利真由美、今野　哲、西村正治、檜澤伸之
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] The role of pulmonary function genes in the pathogenesis of asthma2015
- Author(s)
  Ymada H, Yatagai Y, Masuko H, Kaneko Y, Sakamoto T, Iijima H, Naito T, Noguchi E, Konno S, Nishimura M, Hirota T, Tamari M, Hizawa N.
- Organizer
  American Thoracic Society 2015 International Conference
- Place of Presentation
  Colorado Convention Center (Denver)
- Year and Date
  2015-05-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] モンテルカストとサルメテロールとの効果の差に影響する遺伝子の検討2015
- Author(s)
  山田英恵、谷田貝洋平、増子裕典、坂本　透、飯島弘晃、野口恵美子、今野　哲、清水薫子、牧田比呂仁、西村正治、國分二三男、斎藤武文、遠藤健夫、二宮浩樹、金子教宏、檜澤伸之
- Organizer
  第64回日本アルルギー学会学術大会
- Place of Presentation
  グランドプリンスホテル新高輪（東京）
- Year and Date
  2015-05-26
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 強制オシレーション法による喘息のクラスター分類2015
- Author(s)
  谷田貝洋平、坂本　透、山田英恵、増子裕典、金子美子、小川良子、際本拓未、川口未央、森島祐子、飯島弘晃、檜澤伸之
- Organizer
  第55回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 気管支端息患者phenotypeとADRB2遺伝子多型の検討2013
- Author(s)
  谷田貝洋平(代表)、坂本透、他6名
- Organizer
  第53回日本呼吸器学会学術講演会ミニシンポジウム92
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2013-04-19
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] A Genomewide Association Study In Healthy Japanese Adults Replicated The Previously Reported Susceptibility Genes To Airflow Limitation.2013
- Author(s)
  Yamada H, Yatagai Y, Masuko H, Kaneko Y, Sakamoto T, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Hizawa N.
- Organizer
  American Thoracic Society 2013 International Conference
- Place of Presentation
  Pennsylvania Convention Center（USA）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 日本人における閉塞性換気障害に影響を与える遺伝因子2013
- Author(s)
  山田英恵、谷田貝洋平、増子裕典、金子美子、飯島弘晃、内藤隆志、坂本　透、野口恵美子、広田朝光、玉利真由美、檜澤伸之
- Organizer
  第53回日本呼吸器学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 健常成人の総IgE値、一秒量におけるMUC5B遺伝子の役割2013
- Author(s)
  金子美子、山田英恵、谷田貝洋平、増子裕典、飯島弘晃、内藤隆志、坂本　透、広田朝光、玉利真由美、檜澤伸之
- Organizer
  第53回日本呼吸器学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 喘息の起源としてのアレルゲン特異的IgE反応性の役割－GWASの結果による考察2013
- Author(s)
  谷田貝洋平、山田英恵、金子美子、増子裕典、坂本　透、野口恵美子、飯島弘晃、内藤隆志、広田朝光、玉利真由美、檜澤伸之
- Organizer
  第63回日本アレルギー学会秋期学術大会
- Place of Presentation
  ホテルニューオータニ（東京都）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 喫煙が呼吸器系の形態と機能に及ぼす影響2013
- Author(s)
  坂本透
- Organizer
  第53回日本呼吸器学会学術講演会シンポジウム9
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2013-04-19
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 日本人における閉塞性換気障害に影響を与える遺伝因子2013
- Author(s)
  山田英恵(代表)、坂本透、他9名
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2013-04-19
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 日本人における閉塞性換気障害に影響を与える遺伝因子2013
- Author(s)
  山田英恵、谷田貝洋平、増子裕典、金子美子、飯島弘晃、内藤隆志、坂本　透、野口恵美子、広田朝光、玉利真由美、檜澤伸之
- Organizer
  第25回日本アレルギー学会春季臨床大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 喘息関連遺伝子多型と血清総IgE値関連遺伝子多型のGWASによる比較2013
- Author(s)
  谷田貝洋平、増子裕典、山田英恵、金子美子、坂本　透、飯島弘晃、内藤隆志、野口恵美子、広田朝光、玉利真由美、檜澤伸之
- Organizer
  第25回日本アレルギー学会春季臨床大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] Genome-Wide Association Study Of Serum Total IgE Levels In The Japanese Population Identifies A Novel Responsible Locus In HLA Class I Region.2013
- Author(s)
  Yatagai Y, Masuko H, Yamada H, Kaneko Y, Sakamoto T, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Imoto Y, Tokunaga T, Konno S, Nishimura M, Hizawa N.
- Organizer
  American Thoracic Society 2013 International Conference
- Place of Presentation
  Pennsylvania Convention Center（USA）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 吸入抗原感作数からみた喘息フェノタイプ分類について2013
- Author(s)
  飯島弘晃、山田英恵、谷田貝洋平、金子美子、坂本　透、内藤隆志、今野　哲、西村正治、檜澤伸之
- Organizer
  第53回日本呼吸器学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 気管支端息患者phenotypeとADRB2遺伝子多型の検討2013
- Author(s)
  谷田貝洋平、金子美子、飯島弘晃、山田英恵、坂本　透、今野　哲、西村正治、檜澤伸之
- Organizer
  第53回日本呼吸器学会学術集会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 健常人における一秒量、一秒率及び努力性肺活量における遺伝率の推定2013
- Author(s)
  山田英恵、谷田貝洋平、増子裕典、飯島弘晃、内藤隆志、坂本　透、野口恵美子、広田朝光、玉利真由美、檜澤伸之
- Organizer
  第63回日本アレルギー学会秋期学術大会
- Place of Presentation
  ホテルニューオータニ（東京都）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 喫煙が呼吸器系の形態と機能に及ぼす影響2013
- Author(s)
  坂本　透
- Organizer
  第53回日本呼吸器学会学術集会シンポジウム9
- Place of Presentation
  東京国際フォーラム（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] アトピー分類による喘息phenotypeとTSLP遺伝子との関連2013
- Author(s)
  飯島弘晃、山田英恵、金子美子、谷田貝洋平、坂本　透、内藤隆志、檜澤伸之
- Organizer
  第25回日本アレルギー学会春季臨床大会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 健常成人の総IgE値,一秒量におけるMUC5B遺伝子の役割2013
- Author(s)
  金子美子(代表)、坂本透、他8名
- Organizer
  第53回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2013-04-19
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 環境ダニ抗原量とアトピー分類との関連について2013
- Author(s)
  飯島弘晃、山田英恵、谷田貝洋平、坂本　透、今野　哲、西村正治、檜澤伸之
- Organizer
  第63回日本アレルギー学会秋期学術大会
- Place of Presentation
  ホテルニューオータニ（東京都）
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 日本人における血清総IgE 値に影響を与える遺伝因子-網羅的遺伝子解析による追試-2012
- Author(s)
  谷田貝洋平(代表)、坂本透、他8名
- Organizer
  第52回日本呼吸器学会学術講演会(神戸)
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] Genetic polymorphisms associated with total IgE levels in the Japanese population: A replication analysis by genome-wide association study2012
- Author(s)
  Masuko H. (代表)、Sakamoto T. 他9名
- Organizer
  American Thoracic Society 2012 International Conference
- Place of Presentation
  Moscone Center(San Francisco, USA)
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] The search for common pathways for asthma and COPD.2012
- Author(s)
  Knaneko Y.(代表)、Sakamoto T. 他5名
- Organizer
  American Thoracic Society 2012 International Conference
- Place of Presentation
  Moscone Center(San Francisco, USA)
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 日本人血清総IgE 値のケノムワイド関連解析2012
- Author(s)
  谷田貝洋平(代表)、坂本透、他14名
- Organizer
  第62回日本アレルギー学会秋期学術大会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2012-11-29
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 吸入抗原特異的IgE抗体-MAST26、MAST33とImmunoCARの比較-2012
- Author(s)
  飯島弘晃(代表)、坂本透、他4名
- Organizer
  第62回日本アレルギー学会秋期学術大会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2012-11-29
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 気管支端息におけるアトピー分類と呼吸機能の解析2012
- Author(s)
  山田英恵(代表)、坂本透、他7名
- Organizer
  第62回日本アレルギー学会秋期学術大会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2012-11-29
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 喘息とCOPDにおけるCommon pathwayの探索2012
- Author(s)
  金子美子(代表)、坂本透、他4名
- Organizer
  第62回日本アレルギー学会秋期学術大会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2012-11-29
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] Influences of smoking on the association between thymic stromal lymphopoietin (TSLP) genotypes and IgE responses to inhaled allergens2012
- Author(s)
  Iijima H. (代表)、Sakamoto T. 他8名
- Organizer
  American Thoracic Society 2012 International Conference
- Place of Presentation
  Moscone Center(San Francisco, USA)
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] cluster分析を用いた成人気管支喘息患者表現型の検討2012
- Author(s)
  金子美子(代表)、坂本透、他6名
- Organizer
  第52回日本呼吸器学会学術講演会(神戸)
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2012-04-20
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 健常者における1秒量の経年変化とNrf2遺伝子多型の検討2011
- Author(s)
  増子裕典(代表)、坂本透、他7名
- Organizer
  第23回日本アレルギー学会秋期臨床大会
- Place of Presentation
  グランドプリンスホテル新高輪(東京都)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 健常者における1秒量の経年変化とNrf2遺伝子多型の検討2011
- Author(s)
  増子裕典(代表)、坂本透、他6名
- Organizer
  第51回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2011-04-14
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 23価肺炎球菌ワクチンの特徴とその役割～COPD患者に対する臨床効果エビデンスとガイドライン～2011
- Author(s)
  坂本透
- Organizer
  第12回日本医療マネージメント学会茨城県支部学術集会ランチョンセミナー4
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] Genotypes at CCL5 And TF promoter polymorphisms influence the phenotypic differences in adult asthma2011
- Author(s)
  Kaneko Y.(代表)、Sakamoto T. 他6名
- Organizer
  107th American Thoracic Society International Conference
- Place of Presentation
  Plaza Building (Denver, USA)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] Cluster analyses of IgE responsiveness identified environmental risk factors for asthma2011
- Author(s)
  Iijima H, Masuko H, Kaneko Y, Sakamoto T, Naito T, Hirota T, Tamari M, Konno S, Nishimura M, Hizawa N
- Organizer
  ATS international conference
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] CCL5-28C>G遺伝子多型が健常成人一秒率に与える影響2011
- Author(s)
  金子美子(代表)、坂本透、他5名
- Organizer
  第23回日本アレルギー学会秋期臨床大会
- Place of Presentation
  グランドプリンスホテル新高輪(東京都)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] COPD症例に対する23価肺炎球菌ワクチン接種の重要性2011
- Author(s)
  坂本透
- Organizer
  第22回茨城県薬剤師学術大会ランチョンセミナー
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] A nrf2 polymorphism was associated with annual FEV1 decline in the Japanese population2011
- Author(s)
  Masuko H.(代表)、Sakamoto T. 他6名
- Organizer
  107th American Thoracic Society International Conference
- Place of Presentation
  Plaza Building (Denver, USA)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] CCL5-28C>G遺伝子多型が健常成人一秒率に与える影響2011
- Author(s)
  金子美子, 増子裕典, 坂本透, 飯島弘晃, 内藤隆志, 谷田貝洋平, 檜澤伸之
- Organizer
  日本アレルギー学会
- Place of Presentation
  品川
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] Genotypes at CCL5 and TF promoter polymorphisms influence the phenotypic differences in adult asthma2011
- Author(s)
  Kaneko Y, Masuko H, Sakamoto T, Iijima H, Isada A, Konno S, Nishimura M, Hizawa N
- Organizer
  ATS international conference
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] Cluster analyses of IgE responsiveness identified environmental risk factors for asthma2011
- Author(s)
  Iijima H. (代表)、Sakamoto T. 他8名
- Organizer
  107th American Thoracic Society International Conference
- Place of Presentation
  Plaza Building (Denver, USA)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] A NRF2 polymorphism was associated with annual FEV1 decline in the Japanese population2011
- Author(s)
  Masuko H, Kaneko Y, Sakamoto T, Iijima H, Naito T, Hirota T, Tamari M, Hizawa N
- Organizer
  ATS international conference
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] 健常者一秒率におけるCCL5-28G対立遺伝子の意義について2011
- Author(s)
  金子美子(代表)、坂本透、他4名
- Organizer
  第51回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2011-04-14
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 健常者における1秒量の経年変化とNrf2遺伝子多型の検討2011
- Author(s)
  増子裕典, 金子美子, 飯島弘晃, 内藤隆志, 坂本透, 広田朝光, 玉利真由美, 檜澤伸之
- Organizer
  日本アレルギー学会
- Place of Presentation
  品川
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] 血清総IgE 値、吸入抗原特異的IgE 抗体(MAST)を用いた感作パターンの解析2010
- Author(s)
  飯島弘晃(代表)、坂本透、他6名
- Organizer
  第60回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2010-11-25
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] Decreased pre-bronchodilator FEV1 as a potential risk factor for COPD.2010
- Author(s)
  Masuko H.(代表)、坂本透、他13名
- Organizer
  106th International Conference of American Thoracic Society
- Place of Presentation
  The Convention Center (New Orleans, USA)
- Year and Date
  2010-05-14
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 1秒率正常者における%1秒量の意義について2010
- Author(s)
  増子裕典(代表)、坂本透、他4名
- Place of Presentation
  京都国際会議場(京都府)
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] Decrease dpre-bronchodilator FEV1 as a potential risk factor for COPD2010
- Author(s)
  Masuko H, Sakamoto T, Ano S, Fujita J, Yageta Y, Yamadori T, Kikuchi N, Haraguchi N, Homma S, Kawaguchi M, Morishima Y, Ishii Y, Iijima H, Naito T, Hizawa N
- Organizer
  ATS international conference
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] 健常成人の呼吸機能におけるTSLP遺伝子多型の検討2010
- Author(s)
  増子裕典(代表)、坂本透、他6名
- Organizer
  第60回日本アレルギー学会秋季学術大会
- Place of Presentation
  東京国際フォーラム(東京都)
- Year and Date
  2010-11-25
- Data Source
  KAKENHI-PROJECT-22590834
[Presentation] 外来で吸入ステロイド(ICS)療法を行っている気管支喘息患者の検討2009
- Author(s)
  飯島弘晃, 宮崎邦彦, 清水圭, 金本幸司, 石川博一, 増子裕典, 坂本透, 檜澤伸之
- Organizer
  第59回日本アレルギー学会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] IL-17Fのシグナル伝達経路MSK1-CREBの関与2009
- Author(s)
  藤田純一, 川口未央, 國分二三男, 松倉聡, 森島祐子, 石井幸雄, 坂本透, 足立満, 檜澤伸之
- Organizer
  第21回日本アレルギー学会春季臨床大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] 気道におけるムチン合成に対するモンテルカストの影響喘息患者誘発痰を用いた培養系での検討2009
- Author(s)
  森島祐子, 石井幸雄, 川口未央, 坂本透, 檜澤伸之
- Organizer
  第59回日本アレルギー学会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] 気道上皮細胞からのIL-33によるIL-17Fの産生2009
- Author(s)
  藤田純一, 川口未央, 國分二三男, 松倉聡, 森島裕子, 石井幸雄, 坂本透, 足立満, 檜澤伸之
- Organizer
  第59回日本アレルギー学会
- Place of Presentation
  秋田
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] 気管支喘息発作入院症例の臨床的検討2009
- Author(s)
  飯島弘晃, 藤倉雄二, 塩澤利博, 金本幸司, 石川博一, 増子裕典, 坂本透, 檜澤伸之
- Organizer
  第21回日本アレルギー学会春季臨床大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] 一秒率正常者における%1秒量の意義について2009
- Author(s)
  増子裕典, 坂本透, 飯島弘晃, 内藤隆志, 檜澤伸之
- Organizer
  第21回日本アレルギー学会春季臨床大会
- Place of Presentation
  岐阜
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] COPDとPDE4D遺伝子多型の関連IL13遺伝子多型とのハプロタイプ解析2009
- Author(s)
  増子裕典, 本間晋介, 山鳥忠宏, 菊池教大, 原口典博, 川口未央, 森島祐子, 石井幸雄, 坂本透, 檜澤伸之
- Organizer
  第49回日本呼吸器学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] IL-17Fの新たなシグナル伝達経路:MSK1-CREB2009
- Author(s)
  藤田純一, 川口未央, 國分二三男, 松倉聡, 森島祐子, 石井幸雄, 坂本透, 足立満, 檜澤伸之
- Organizer
  第49回日本呼吸器学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] 気道上皮細胞に対するCysLT1受容体拮抗薬の影響喘息患者誘発痰を用いた培養系での検討2009
- Author(s)
  森島祐子, 野村明広, 石井幸雄, 本間晋介, 菊池教大, 原口典博, 山鳥忠宏, 川口未央, 坂本透, 檜澤伸之
- Organizer
  第49回日本呼吸器学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21390254
[Presentation] 喘息発症における呼吸機能関連遺伝子の役割
- Author(s)
  山田英恵、谷田貝洋平、増子裕典、飯島弘晃、内藤隆志、坂本　透、野口恵美子、広田朝光、玉利真由美、檜澤伸之
- Organizer
  第54回日本呼吸器学会学術講演会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-04-25 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] COPDに対するSalmeterol/Fluticasone配合剤の追加効果および効果予測因子に関する検討
- Author(s)
  飯島弘晃、坂本　透、野村明広、児玉孝秀、山本祐介、橋本健一、鏑木孝之、檜澤伸之
- Organizer
  第54回日本呼吸器学会学術講演会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-04-25 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] Hyaluronan synthase 2 (HAS2)遺伝子と喘息との関連-ゲノムワイド関連解析（ＧＷＡＳ）による検討-
- Author(s)
  谷田貝洋平、山田英恵、増子裕典、金子美子、飯島弘晃、内藤隆志、坂本　透、野口恵美子、広田朝光、玉利真由美、檜澤伸之
- Organizer
  第54回日本呼吸器学会学術講演会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-04-25 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] Genome-wide association study identifies hyaluronan synthase 2 (HAS2) as a susceptibility gene for adult asthma in a Japanese population
- Author(s)
  Yatagai Y, Sakamoto T, Yamada H, Masuko H, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Hizawa N.
- Organizer
  American Thoracic Society 2014 International Conferenc
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 健常人における吸入抗原のアレルギー感作に対するゲノム網羅的関連解析
- Author(s)
  山田英恵、谷田貝洋平、増子裕典、飯島弘晃、内藤隆志、坂本　透、野口恵美子、広田朝光、玉利真由美、檜澤伸之
- Organizer
  第26回日本アレルギー学会春期臨床大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-05-09 – 2014-05-11
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] The role of lung function genes in the development of asthma
- Author(s)
  Yamada H, Yatagai Y, Masuko H, Sakamoto T, Iijima H, Naito T, Noguchi E, Hirota T, Tamari M, Hizawa N.
- Organizer
  American Thoracic Society 2014 International Conferenc
- Place of Presentation
  San Diego Convention Center
- Year and Date
  2014-05-16 – 2014-05-21
- Data Source
  KAKENHI-PROJECT-25461147
[Presentation] 中高年発症喘息（late onset asthma: LOA）を対象とした網羅的遺伝子解析
- Author(s)
  谷田貝洋平、山田英恵、金子美子、増子裕典、坂本　透、野口恵美子、飯島弘晃、内藤隆志、広田朝光、玉利真由美、今野　哲、西村正治、檜澤伸之
- Organizer
  第26回日本アレルギー学会春期臨床大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-05-09 – 2014-05-11
- Data Source
  KAKENHI-PROJECT-25461147

1. HIZAWA Nobuyuki (00301896)

# of Collaborated Projects: 4 results

# of Collaborated Products: 100 results
2. NOGUCHI Emiko (40344882)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
3. TAMARI Mayumi (00217184)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
4. NAKAJIMA Masayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. FUJITA Junichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. OTA Kyoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 渋谷彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 石井幸雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 川口未央

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakamoto Tohru 坂本 透

SAKAMOTO Tohru 坂本 透

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Personalized prediction of susceptibility to asthma by genetic risk scorePrincipal Investigator

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Comprehensive analysis of risk factors for asthma and COPD by prospective cohort studyPrincipal Investigator

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Risk factors for inflammatory obstructive pulmonary diseases: a prospective cohort study.Principal Investigator

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Study on the pathogenesis of asthma and COPD-genetic heterogeneity and pharmacogenetics-

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[Book] Advances in Asthma2019

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[Book] COPD2019

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[Journal Article] Effects of Lung Function-Related Genes and TSLP on COPD Phenotypes2020

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[Journal Article] A cis-eQTL allele regulating reduced expression of CHI3L1 is associated with late-onset adult asthma in Japanese cohorts.2019

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[Journal Article] Association analyses of eQTLs of the <i>TYRO3</i> gene and allergic diseases in Japanese populations2019

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[Journal Article] The Concavity of the Maximal Expiratory Flow?Volume Curve Reflects the Extent of Emphysema in Obstructive Lung Diseases2019

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[Journal Article] How important is allergic sensitization as a cause of atopic asthma?2018

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[Journal Article] Transcription elongation factor P-TEFb is involved in IL-17F signaling in airway smooth muscle cells.2018

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Sakamoto Tohru 坂本透

SAKAMOTO Tohru 坂本透