TAMBE Yukihiro 旦部幸博

… Alternative Names

Yukihiro Tambe 旦部幸博

Less

Researcher Number	50283560
Other IDs
Affiliation (Current)	2022: 滋賀医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 滋賀医科大学, 医学部, 准教授 2016 – 2018: 滋賀医科大学, 医学部, 助教 2007 – 2013: Shiga University of Medical Science, 医学部, 助教 2006: 滋賀医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Experimental pathology / Tumor therapeutics / Basic Section 50010:Tumor biology-related / Basic Section 49030:Experimental pathology-related
Keywords	Principal Investigator Drs遺伝子 / 癌 / 代謝 / 癌抑制遺伝子 / グルコース代謝 / drs / オートファジー / Rab24 / 癌制御遺伝子 / ストレス応答 … More / drs遺伝子 / 感染防御 / 自然免疫 / mTOR / GADD34 / 感染防御作用 / メタボローム / 乳酸脱水素酵素 / エネルギー代謝 / ワールブルグ効果 / 分子標的薬 / 抗腫瘍活性 / ペプチド模倣 / drs/SRPX / sushiモチーフ / 分子模倣 / 抗癌剤 / Drs癌抑制遺伝子 / Sushiモチーフ / 生理活性 / 薬学 / 生体機能利用 / シグナル伝達 / レドックス制御 / Drs / クリプトタンシノン / ピルビン酸脱水素酵素4 / 代謝シフト / 癌抑制遺伝子Drs / Kras / ROS / 悪性腫瘍 / 感染防御機構 / ウイルス Less

ウイルス感染が誘導する代謝リプログラミングに対するDrs遺伝子の作用Principal Investigator
- Principal Investigator
  
  旦部幸博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Shiga University of Medical Science
Association between redox regulation by the tumor suppressor gene Drs and malignant transformation of cancerPrincipal Investigator
- Principal Investigator
  
  TAMBE YUKIHIRO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Shiga University of Medical Science
Development of novel antitumor peptidomimetic drugs targeting Drs/SRPX tumor suppressorPrincipal Investigator
- Principal Investigator
  
  Yukihiro Tambe
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Shiga University of Medical Science
Regulation of metabolic shift by drs tumor suppressor genePrincipal Investigator
- Principal Investigator
  
  TAMBE Yukihiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Shiga University of Medical Science
Role of drs tumor suppressor gene on host defense mechanism against infectionPrincipal Investigator
- Principal Investigator
  
  TAMBE Yukihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Shiga University of Medical Science
癌抑制遺伝子drsによるオートファジー誘導機構の解明Principal Investigator
- Principal Investigator
  
  旦部幸博
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Shiga University of Medical Science

All 2021 2020 2019 2018 2017 2016 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Cryptotanshinone, a novel PDK 4 inhibitor, suppresses bladder cancer cell invasiveness via the mTOR/β-catenin/N-cadherin axis2021
- Author(s)
  CJ Kim, T Terado, Y Tambe, K Mukaisho, S Kageyama, A Kawauchi, H Inoue
- Journal Title
  
  Int. J. Oncol
  
  Volume: －
- NAID
  120007041321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07663
[Journal Article] Cryptotanshinone, a novel PDK 4 inhibitor, suppresses bladder cancer cell invasiveness via the mTOR/β-catenin/N-cadherin axis2021
- Author(s)
  Chul Jang Kim, Tokio Terado, Yukihiro Tambe, Ken-ichi Mukaisho, Susumu Kageyama, Akihiro Kawauchi, Hirokazu Inoue
- Journal Title
  
  Int J Oncol
  
  Volume: 59 Pages: 40-40
- DOI
  10.3892/ijo.2021.5220
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07480, KAKENHI-PROJECT-19K07663, KAKENHI-PROJECT-19K09687, KAKENHI-PROJECT-21K09342
[Journal Article] Antitumor activity of potent pyruvate dehydrogenase kinase 4 inhibitors from plants in pancreatic cancer2019
- Author(s)
  Tambe Y, Terado T, Kim CJ, Mukaisho K, Yoshida S, Sugihara H, Tanaka H, Chida J, Kido H, Yamaji K, Yamamoto T, Nakano G, Omura S, Inoue H
- Journal Title
  
  Molecular Carcinogenesis
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07169
[Journal Article] Antitumor activity of potent pyruvate dehydrogenase kinase 4 inhibitors from plants in pancreatic cancer2019
- Author(s)
  Tambe, Y., Terado, T., Kim, C. J., Mukaisho, K., Yoshida, S., Sugihara, H., Tanaka, H., Chida, J., Kido, H., Yamaji, K., Yamamoto, T., Nakano, H., Omura, S. and Inoue, H.
- Journal Title
  
  Mol Carcinog
  
  Volume: 58 Pages: 1726-1737
- DOI
  10.1002/mc.23045
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07480, KAKENHI-PROJECT-19K07663, KAKENHI-PROJECT-19K09687
[Journal Article] Anti-oncogenic activities of cyclin D1b siRNA on human bladder cancer cells via induction of apoptosis and suppression of cancer cell stemness and invasiveness.2018
- Author(s)
  Kim CJ, Terado T, Tambe Y, Mukaisho KI, Sugihara H, Kawauchi A, Inoue H.
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 52 Pages: 231-240
- DOI
  10.3892/ijo.2017.4194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07169, KAKENHI-PROJECT-16K08711
[Journal Article] Periostin suppresses in vivo invasiveness via PDK1/Akt/mTOR signaling pathway in a mouse orthotopic model of bladder cancer2017
- Author(s)
  Kim, C. J., Tambe, Y., Mukaisho, K., Sugihara, H., Kageyama, S., Kawauchi, A., Inoue, H.
- Journal Title
  
  Oncol. Lett.
  
  Volume: 13 Pages: 4247-4284
- DOI
  10.3892/ol.2017.6004
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08711, KAKENHI-PROJECT-16K07169, KAKENHI-PROJECT-16K11001
[Journal Article] Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity2016
- Author(s)
  Kim CJ, Tambe Y, Mukaisho KI, Sugihara H, Kawauchi A, Inoue H.
- Journal Title
  
  Oncol Lett
  
  Volume: 12 Pages: 4850-4856
- DOI
  10.3892/ol.2016.5286
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07169, KAKENHI-PROJECT-16K08711, KAKENHI-PROJECT-16K11001
[Journal Article] Female specific rectal carcinogenesis in cyclin D1b transgenic mice2014
- Author(s)
  Tambe, Y., Kim, C. J., Munkaisho, K., Sugihara, H., Isono, T., Sonoda, H., Shimizu, T., Kondoh, G., Inoue, H.
- Journal Title
  
  Carcinogenesis
  
  Volume: 35 Pages: 227-236
- DOI
  10.1093/carcin/bgt293
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23590457, KAKENHI-PROJECT-24590480, KAKENHI-PROJECT-25250012, KAKENHI-PROJECT-25462476
[Journal Article] Suppression of viral replication by drs tumor suppressor via mTOR dependent pathway.2012
- Author(s)
  Tambe, Y., et al
- Journal Title
  
  Cancer Lett.
  
  Volume: 314 Pages: 82-91
- DOI
  10.1016/j.canlet.2011.09.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590437, KAKENHI-PROJECT-23390148, KAKENHI-PROJECT-23590457
[Journal Article] Suppression of viral replication by drs tumor suppressor via mTOR dependent pathway.2012
- Author(s)
  Tambe Y, Okuyama N, Nakagawa T, Muramoto A, Hasebe M, Chano T, Inoue H.
- Journal Title
  
  Cancer Lett.
  
  Volume: 314 Pages: 82-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590457
[Journal Article] Opposite regulation of epithelial to mesenchymal transition and cell invasiveness by periostin between prostate and bladder cancer cells.2011
- Author(s)
  Chul Jang Kim, Kanami Sakamoto, Yukihiro Tambe, Hirokazu Inoue.
- Journal Title
  
  Int J Oncol.Vol. 38
  
  Pages: 1759-1766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590383
[Journal Article] Opposite regulation of epithelial to mesenchymal transition and cell invasiveness by periostin between prostate and bladder cancer cells2011
- Author(s)
  Kim, C.J., et al
- Journal Title
  
  Int J Oncol.
  
  Volume: 38 Pages: 1759-1766
- DOI
  10.3892/ijo.2011.997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590437, KAKENHI-PROJECT-23590457
[Journal Article] Opposite regulation of epithelial-to-mesenchymal transition and cell invasiveness by periostin between prostate and bladder cancer cells.2011
- Author(s)
  Kim, C.J., Sakamoto, K., Tambe, Y., Inoue, H.
- Journal Title
  
  Int.J.Oncol.
  
  Volume: 38 Pages: 1759-1766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590383
[Journal Article] Cyclin Dlb variant prpmotes cell invasiveness independent of binding to CDK in human bladder cancer cells.2009
- Author(s)
  Kim, C. J., Nishi, K., Isono, T., Okuyama, Y., Tambe, Y., Okada, Y., Inoue, H.
- Journal Title
  
  Molecular Carcinogenesis (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590383
[Journal Article] Cyclin D1b variant promotes cell invasiveness independent of binding to CDK in human bladder cancer cells2009
- Author(s)
  Kim, C.J., Nishi, K., Isono, T., Okuyama, Y., Tambe, Y., Okada, Y., Inoue, H.
- Journal Title
  
  Molecular Carcinogenesis 48
  
  Pages: 953-964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590383
[Journal Article] The Drs tumor suppressor is involved in the maturation process of autophagy induced by low serum.2009
- Author(s)
  Tambe, Y., Yamamoto, A., Isono, T., Chano, T., Fukuda, M., Inoue, H.
- Journal Title
  
  Cancer Letters (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590383
[Journal Article] The Drs tumor suppressor is involved in the maturation process of autophagy induced by low serum.2009
- Author(s)
  Yukihiro Tambe, Akitsugu Yamamoto, Takahiro Isono, Tokuhiro Chano, Mitsunori Fukuda, Hirokazu Inoue.
- Journal Title
  
  Cancer Letters Vol.283
  
  Pages: 74-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590383
[Journal Article] Cyclin D1b variant promotes cell invasiveness independent of binding to CDK in human bladder cancer cells.2009
- Author(s)
  Chul Jang Kim, Kayoko Nishi, Takahiro Isono, Yusuke Okuyama, Yukihiro Tambe, Yusaku Okada, Hirokazu Inoue.
- Journal Title
  
  Mol.Carcinog. Vol.48
  
  Pages: 953-964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590383
[Journal Article] The Drs tumor suppressor is involved in the maturation process of autophagy induced by low serum2009
- Author(s)
  Tambe, Y., Yamamoto, A., Isono, T., Chano, T., Fukuda, M., Inoue, H.
- Journal Title
  
  Cancer Letters 283
  
  Pages: 74-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590383
[Journal Article] Role of alternative splicing of periostin in human bladder carcinogenesis.2008
- Author(s)
  Chul Jang Kim, Takahiro Isono, Yukihiro Tambe, Tokuhiro Chano, Hidetoshi Okabe, Yusaku Okada, Hirokazu Inoue.
- Journal Title
  
  Int.J.Oncol. Vol.32
  
  Pages: 161-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590383
[Journal Article] Role of alternative splicing of periostin in human bladder carcinogenesis.2008
- Author(s)
  Kim, C. J., Isono, T., Tambe, Y., Chano, T., Okabe, H., Okada, Y. Inoue, H.
- Journal Title
  
  Int. J. Oncol. 32
  
  Pages: 161-169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590383
[Journal Article] Tumor prone phenotype of mice deficient in a novel apoptosis-inducing gene, drs.2007
- Author(s)
  Tambe Y, Yoshioka-Yamashita A et al.
- Journal Title
  
  Carcinogenesis 28 (4)
  
  Pages: 777-784
- Data Source
  KAKENHI-PROJECT-18790270
[Journal Article] GADD34 inhibits mammalian target of rapamycin signaling via tuberous sclerosis complex and controls cell survival under bioenergetic stress.2007
- Author(s)
  Watanabe R, Tambe Y et al.
- Journal Title
  
  Int J Mol Med. 19 (3)
  
  Pages: 475-483
- Data Source
  KAKENHI-PROJECT-18790270
[Journal Article] Tumor prone phenotype of mice deficient in a novel apoptosis-inducing gene, drs.2007
- Author(s)
  Tambe, Y
- Journal Title
  
  Carcinogenesis 28
  
  Pages: 777-784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790270
[Journal Article] Down-regulation of drs mRNA is associated with the progression of adult T-cell leukemia/lymphoma.
- Author(s)
  Shimakage M, Inoue N, Tambe Y et al.
- Journal Title
  
  Int. J. Oncol. (in press)
- Data Source
  KAKENHI-PROJECT-18790270
[Presentation] PDK4 阻害剤クリプトタンシノンは、脂質の代謝を阻害し、KRAS活性化癌細胞の腫瘍化を抑制する2021
- Author(s)
  寺戸勅雄, 旦部幸博, 金哲將, 田中裕之, 井上寛一
- Organizer
  第80回日本癌学会学術総会（横浜） 2021年10月1日
- Data Source
  KAKENHI-PROJECT-19K07663
[Presentation] ヒト膀胱癌細胞における beta-catenin/N-cadherin を介した新規PDK4 阻害剤クリプトタンシノンによる浸潤抑制2021
- Author(s)
  金哲將, 寺戸勅雄, 旦部幸博, 向所賢一, 影山進, 河内明宏, 井上寛一
- Organizer
  第80回日本癌学会学術総会（横浜） 2021年10月1日
- Data Source
  KAKENHI-PROJECT-19K07663
[Presentation] 新規 PDK4 阻害剤 cryptotanshinone はグルタミン代謝を阻害して KRAS 活性化癌を抑制する2020
- Author(s)
  寺戸勅雄;旦部幸博;金哲將;田中裕之;向所賢一;杉原洋行;井上寛一
- Organizer
  第79回日本癌学会学術総会（広島）
- Data Source
  KAKENHI-PROJECT-19K07663
[Presentation] ヒト膀胱・膵癌における PDK4 阻害剤としてのクリプトタンシノンによる浸潤・転移抑制2020
- Author(s)
  金哲將, 寺戸勅雄, 旦部幸博, 向所賢一, 影山進, 河内明宏, 井上寛一
- Organizer
  第79回日本癌学会学術総会（広島）
- Data Source
  KAKENHI-PROJECT-19K07663
[Presentation] A novel PDK4 inhibitor cryptotanshinone suppresses the tumorigenesis of KRAS-activated cancer cells via PI3K/Akt pathway2019
- Author(s)
  Yukihiro Tambe, Tokio Terado, Chul Jang Kim, Hirofumi Nakano, Ken-ichi Mukaisho, Hiroyuki Sugihara, Hirokazu Inoue
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-19K07663
[Presentation] Suppression of invasion and metastasis by a novel PDK4 inhibitor in pancreatic and bladder cancers2019
- Author(s)
  Chul Jang Kim, Tokio Terado, Yukihiro Tambe, Akihiro Kawauchi, Ken-ichi Mukaisho, Hiroyuki Sugihara, Hirokazu Inoue
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-19K07663
[Presentation] 新規PDK4阻害剤クリプトタンシノンの膵臓癌に対する抗腫瘍作用2019
- Author(s)
  旦部幸博, 寺戸勅雄, 金哲將, 向所賢一, 中野洋文, 井上寛一
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07663
[Presentation] Antitumor activity of a novel PDK4 inhibitor, cryptotanshinone,in pancreatic cancer by suppressing the KRAS expression2018
- Author(s)
  Yukihiro Tambe, Tokio Terado, Chul Jang Kim, Hirofumi Nakano, Ken-ichi Mukaisho, Hiroyuki Sugihara, Hirokazu Inoue
- Organizer
  第77回日本癌学会総会（大阪）
- Data Source
  KAKENHI-PROJECT-16K07169
[Presentation] Anti-oncogenic activity of a novel PDK4 inhibitor in bladdercancer by suppressing the H-Ras and cancer stemness2018
- Author(s)
  Chul Jang Kim, Tokio Terado, Yukihiro Tambe, Hirofumi Nakano, Akihiro Kawauchi, Hirokazu Inoue
- Organizer
  第77回日本癌学会総会（大阪）
- Data Source
  KAKENHI-PROJECT-16K07169
[Presentation] Cyclin D1bトランスジェニックマウスにはSSA/P類似直腸腫瘍が発生する2017
- Author(s)
  向所賢一、旦部幸博、金哲將、園田寛道、清水智治、谷眞至、杉原洋行、井上寛一
- Organizer
  第86回大腸癌研究会
- Place of Presentation
  盛岡市
- Year and Date
  2017-01-20
- Data Source
  KAKENHI-PROJECT-16K07169
[Presentation] ヒト膵臓癌細胞株のin vivo造腫瘍能と癌幹細胞性に対するPDK4阻害剤の作用2017
- Author(s)
  旦部幸博, 寺戸勅雄, 金哲將, 中野洋文, 向所賢一, 杉原洋行, 井上寛一
- Organizer
  第76回日本癌学会学術総会（横浜）
- Data Source
  KAKENHI-PROJECT-16K07169
[Presentation] Molecular mechanism of the regulation of Warburg effect by the drs tumor suppressor gene2013
- Author(s)
  Yukihiro Tambe, Hirokazu Inoue
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Cyclin D1b トランスジェニックマウスにおける雌特異的直腸腫瘍発生の分子機構の解析2013
- Author(s)
  金哲將、旦部幸博、向所賢一、杉原洋行、井上寛一
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Molecular mechanism of female specific rectal carcinogenesis in cyclin D1b transgenic mice2013
- Author(s)
  Chul Jang Kim, Yukihiro Tambe, Ken ichi Mukaisho, Hiroyuki Sugihara, Hirokazu Inoue
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2013-10-05
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Cyclin D1bトランスジェニックマウスにおける雌特異的直腸腫瘍発生の分子機構2013
- Author(s)
  旦部幸博、金哲將、向所賢一、杉原洋行、井上寛一
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Molecular mechanism of female specific rectal carcinogenesis in cyclin D1b transgenic mice2013
- Author(s)
  Yukihiro Tambe, Chul Jang Kim, Ken ichi Mukaisho, Hiroyuki Sugihara, Hirokazu Inoue
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-05
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] drs がん抑制遺伝子による Warburg 効果制御の分子機構2013
- Author(s)
  旦部幸博、井上寛一
- Organizer
  第72回日本癌学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] The drs tumor suppressor gene is involved in regulation of Warburg effect2012
- Author(s)
  Yukihiro Tambe, Hirokazu Inoue
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Studies on the oncogenic potential of rectal tumor developed in cyclic D1b transgenic mice2012
- Author(s)
  Chul Jang Kim, Yukihiro Tambe, Ken ichi Mukaisho, Hiroyuki Sugihara, Takahiro Isono, Gen Kondoh, Hirokazu Inoue
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Studies on the oncogenic potential of rectal tumor developed in cyclic D1b transgenic mice2012
- Author(s)
  Chul Jang Kim, Yukihiro Tambe, Ken-ichi Mukaisho, Hiroyuki Sugihara, Takahiro Isono, Gen Kondoh, Hirokazu Inoue.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Drs tumor suppressor gene is involved in regulation of Warburg effect2012
- Author(s)
  Masahiro Hasebe, Akitsugu Yamamoto, Yukihiro Tambe, Hirokazu Inoue
- Organizer
  第35回分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] The drs tumor suppressor gene is involved in regulation of Warburg effect2012
- Author(s)
  Yukihiro Tambe, Hirokazu Inoue.
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] In vivo and in vitro oncogenic potential of human cyclin D1b variant2012
- Author(s)
  Hirokazu Inoue, Yukihiro Tambe, Ken ichi Mukaisho, Hiroyuki Sugihara, Takahiro Isono, Gen Kondoh, Chul Jang Kim
- Organizer
  第71回日本癌学会総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] In vivo and in vitro oncogenic potential of human cyclin D1b variant2012
- Author(s)
  Hirokazu Inoue, Yukihiro Tambe, Ken-ichi Mukaisho, Hiroyuki Sugihara, Takahiro Isono, Gen Kondoh, Chul Jang Kim
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Female-specific development of rectal cancers via serrated pathway in cyclin D1b-transgenic mice2012
- Author(s)
  Yukihiro Tambe, Chul Jang Kim, Ken-ichi Mukaisho, Hiroyuki Sugihara, Takahiro Isono, Hiromichi Sonoda, Tomoharu Shimizu, Gen Kondoh, Hirokazu Inoue
- Organizer
  第35回分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Female specific development of rectal cancers via serrated pathway in cyclin D1b transgenic mice2012
- Author(s)
  Yukihiro Tambe, Chul Jang Kim, Ken ichi Mukaisho, Hiroyuki Sugihara, Takahiro Isono, Hiromichi Sonoda, Tomoharu Shimizu, Gen Kondoh, Hirokazu Inoue
- Organizer
  第35回分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Role of the drs tumor suppressor in regulation of energy metabolism2011
- Author(s)
  Yukihiro Tambe, Hirokazu Inoue
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Role of cyclin D1b variant in rectal tumorigenesis2011
- Author(s)
  Chul Jang Kim, Yukihiro Tambe, Takahiro Isono, Ken ichi Mukaisho, Hiroyuki Sugihara, Gen Kondoh, Hirokazu Inoue
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Roll of the drs tumor suppressor in regulation of energy metabolism2011
- Author(s)
  Yukihiro Tambe, Hirokazu Inoue.
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590457
[Presentation] Cell-type dependent regulation of EMT and cell invasiveness of human cancer cells by periostin2010
- Author(s)
  Hirokazu Inoue, Kanami Sakamoto, Yukihiro Tambe, Chul Jang Kim
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  ポートアイランド(神戸)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] drsによるウイルス増殖抑制作用2010
- Author(s)
  旦部幸博, 奥山直美, 中川達也, 井上寛一
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  ポートアイランド(神戸)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Cell-type dependent regulation of EMT and cell invasiveness of cancer cells by periostin2010
- Author(s)
  Chul Jang Kim, Yukihiro Tambe, Hirokazu Inoue.
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル大阪(大阪)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] The drs tumor suppressor is involved in the suppression of viral replication via p38-RSK1-S6 dependent pathway2010
- Author(s)
  Yukihiro Tambe, Tokuhiro Chano, Hirokazu Inoue
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル大阪(大阪)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] The drs tumor suppressor is involved in the suppression of viral replication via p38-RSK1-S6 dependent pathway2010
- Author(s)
  旦部幸博, 茶野徳宏, 井上寛一.
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] 癌抑制遺伝子drsによるウイルス増殖抑制作用2010
- Author(s)
  旦部幸博, 奥山直美, 中川達也, 井上寛一
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Cell-type dependent regulation of EMT and cell invasiveness of cancer cells by periostin2010
- Author(s)
  Chul Jang Kim, Yukihiro Tambe, Hirokazu Inoue
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Cell-type dependent regulation of EMT and cell invasiveness of human cancer cells by periostin2010
- Author(s)
  Hirokazu Inoue, Kanami Sakamoto, Yukihiro Tambe, Chul Jang Kim
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Regulation of autophagy maturation by the interaction of Drs tumor suppressor and Rab24.2009
- Author(s)
  旦部幸博, 礒野高敬, 茶野徳宏, 井上寛一.
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2009-10-28
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Cyclin D1b variant enhances cell invasiveness of human bladder cancer cells.2009
- Author(s)
  Chul Jang Kim, Takahiro Isono, Yukihiro Tambe, Yusaku Okada, Hirokazu Inoue
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2009-10-28
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Functional analysis of variant cyclin D1b on enhances cell invasiveness of human bladder cancer cells2009
- Author(s)
  Chul Jang Kim, Takahiro Isono, Yukihiro Tambe, Yusaku Okada, Hirokazu Inoue
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Suppression of viral replication by the drs tumor suppressor genes.2009
- Author(s)
  旦部幸博, 井上寛一.
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Role of drs tumor suppressor gene in cell survival under energy depletion.2009
- Author(s)
  井上寛一, 茶野徳宏, 旦部幸博.
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Suppression of viral replication by the drs tumor suppressor genes2009
- Author(s)
  Yukihiro Tambe, Hirokazu Inoue
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Role of drs tumor suppressor gene in cell survival under energy depletion2009
- Author(s)
  Hirokazu Inoue, Tokuhiro Chano, Yukihiro Tambe
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Splicing variant cyclin Dlbによる膀胱癌細胞の悪性化促進の解析2008
- Author(s)
  井上寛一, 西香代子, 奥山雄介, 旦部幸博, 岡田裕作, 礒野高敬, 金哲將
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] エネルギー枯渇に対するストレス応答における癌抑制遺伝子drsの役割2008
- Author(s)
  旦部幸博, 前田理亜, 山本章嗣, 茶野徳宏, 井上寛一
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Regulation of autophagy maturation by the interaction of Drs tumor suppressor and Rab24.2008
- Author(s)
  Yukihiro Tambe, Takahiro Isono, Tokuhiro Chano, Hirokazu Inoue.
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Cyclin Dlb variant enhances cell invasiveness of human bladder cancer cells.2008
- Author(s)
  Chul Jang Kim, Takahiro Isono, Yukihiro Tambe, Yusaku Okada, Hirokazu Inoue.
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-28
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] Splicing variant cyclin D1b による膀胱癌細胞の悪性化促進の解析2008
- Author(s)
  井上寛一、西香代子、奥山雄介、旦部幸博、岡田裕作、礒野高敬、金哲將
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] エネルギー枯渇に対するストレス応答における癌抑制遺伝子drs の役割2008
- Author(s)
  旦部幸博、前田理亜、山本章嗣、茶野徳宏、井上寛一
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20590383
[Presentation] An apoptosis inducing tumor suppressor, Drs, interacts with Rab24 and regulates the maturation process of autophagy2007
- Author(s)
  Tambe, Y
- Organizer
  第66回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-18790270

1. INOUE Hirokazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
2. KIM Chul-Jang

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. TERADO Tokio

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. NAKANO Hirofumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. Kim Chul Jang

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. Mukaisho Ken-ichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 河内明宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
8. 茶野徳宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 影山進

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 金哲将

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 近藤科江

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 近藤玄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

TAMBE Yukihiro 旦部 幸博

Yukihiro Tambe 旦部 幸博

Research Projects

Research Products

Co-Researchers

ウイルス感染が誘導する代謝リプログラミングに対するDrs遺伝子の作用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Association between redox regulation by the tumor suppressor gene Drs and malignant transformation of cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel antitumor peptidomimetic drugs targeting Drs/SRPX tumor suppressorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of metabolic shift by drs tumor suppressor genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of drs tumor suppressor gene on host defense mechanism against infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

癌抑制遺伝子drsによるオートファジー誘導機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cryptotanshinone, a novel PDK 4 inhibitor, suppresses bladder cancer cell invasiveness via the mTOR/β-catenin/N-cadherin axis2021

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Cryptotanshinone, a novel PDK 4 inhibitor, suppresses bladder cancer cell invasiveness via the mTOR/β-catenin/N-cadherin axis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Antitumor activity of potent pyruvate dehydrogenase kinase 4 inhibitors from plants in pancreatic cancer2019

Author(s)

Journal Title

Data Source

[Journal Article] Antitumor activity of potent pyruvate dehydrogenase kinase 4 inhibitors from plants in pancreatic cancer2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-oncogenic activities of cyclin D1b siRNA on human bladder cancer cells via induction of apoptosis and suppression of cancer cell stemness and invasiveness.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Periostin suppresses in vivo invasiveness via PDK1/Akt/mTOR signaling pathway in a mouse orthotopic model of bladder cancer2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Akt-dependent activation of Erk by cyclin D1b contributes to cell invasiveness and tumorigenicity2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Female specific rectal carcinogenesis in cyclin D1b transgenic mice2014

Author(s)

Journal Title

DOI

Data Source

TAMBE Yukihiro 旦部幸博

Yukihiro Tambe 旦部幸博