Kobayashi Akira 小林聡

… Alternative Names

KOBAYASHI AKIRA 小林聡

KOBAYASHI Akira 小林聡

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Researcher Number	50292214
Other IDs
Affiliation (Current)	2025: 同志社大学, 生命医科学部, 教授
Affiliation (based on the past Project Information) *help	2014 – 2024: 同志社大学, 生命医科学部, 教授 2011: 同志社大学, 生命医科学部, 教授 2010: 同志社大学, 生命医科学部, 准教授 2008: Doshisha University, 生命医科学部, 准教授 2007: Tohoku University, 大学院・医学系研究科, 准教授 … More 2006: Tohoku university, Graduate School of Medicine, Lecture, 大学院医学系研究科, 講師 2005: 筑波大学, 大学院・人間総合科学研究科, 講師 2002 – 2003: Basic Medicine, Instructor, 基礎医学系, 講師 1999 – 2001: 東北大学, 大学院・医学系研究科, 助手 1999: Tohoku University, Graduate School of Medicine, Assistant Professor 1998: 東北大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / General medical chemistry / Basic Section 59040:Nutrition science and health science-related / Biological Sciences / General medical chemistry / Applied health science Except Principal Investigator Basic Section 50010:Tumor biology-related / Functional biochemistry / General medical chemistry / Pathological medical chemistry
Keywords	Principal Investigator 転写因子 / 転写制御 / 遺伝子発現 / タンパク質分解 / プロテアソーム / シグナル伝達 / ユビキチン / 酸化ストレス / タンパク質恒常性 / ストレス … More / タンパク質構造 / センサー / T細胞 / 細胞死 / 発ガン / 分子進化 / クロマチン構造 / 造血細胞分化 / 膵臓がん / がん / マクロピノサイトーシス / NRF3 / 腫瘍微小環境 / アルギニン / アンチエイジング / ストレス応答 / 脂質代謝 / 蛋白質 / 細胞内局在 / bZipドメイン / CNCファミリー / 転写因子ネットワーク / 転写調節因子 / 発生 / 血球細胞分化 / 細胞増殖因子 / アミノ酸トランスポーター / 腫瘍増大機構 / アミノ酸飢餓 / 腫瘍増大 / がん免疫回避 / アミノ酸トランスポータ / アグリファジー / ユビキチン－プロテアソーム / プロテオスタシス / 活性化メカニズム / オートファジー / タンパク質品質管理 / GABARAPL1 / p62 / NRF1 / 選択的オートファジー / ユビキチン-プロテアソーム系 / ドラッグリポジショニング / 免疫チェックポイント阻害療法 / 膵臓ガン / がん免疫 / 腫瘍悪性化機構 / CTGF / 乳酸 / LDHA / 代謝 / 免疫疲弊 / 免疫回避 / アミノ酸シグナル / 腫瘍悪性化 / 寿命延長 / シグナル伝達経路 / アルギニン欠乏 / mTORC1 / 腫瘍免疫 / アミノ酸 / 染色体ダイナミクス / 連動的遺伝子発現 / 連動的制御機構 / 転写 / 老化 / ubiquitin / protein degradation / oxidative stress / stress response / ユビキチン化 / 蛋白質分解 / T cell / apoptosis / cancer development / transcription factor / Transcriptional regulation / タンパク質分解機構 / 遺伝子発現制御 / 脂質代謝異常 / 遺伝子発現制 / 遺伝子破壊マウス / ストレス感知 / 免疫制御 / 転写調節 / タンパク質間相互作用 / BTBドメイン … More Except Principal Investigator NRF3 / FGF4 / BTEB2 / BTEB / LCR / ノックアウトマウス / Heme / 5-アミノレブリン酸合成酵素 / Nrf3 / Bach1 / ヘム / 転写調節 / 転写因子 / 腫瘍免疫 / 肥満 / 肥満パラドックス / 免疫逃避 / がん / ユビキチン非依存的タンパク質分解 / 20Sプロテアソーム / NRF3 (NFE2L3) / がん増悪 / プロテアソーム / 翻訳 / CPEB3 / NRF1 / マクロピノサイトーシス / コレステロール / 脂質代謝 / タンパク質分解 / 腫瘍 / 遺伝子発現 / hippocampus / cerebellum / gene-knockout mice / GCbox consensus sequence / targeting vectors / T_3 / β-gal / 標的遺伝子 / in vitro / ホモ欠失マウス / ターゲッティングペクター / 海馬 / 小脳 / 遺伝子欠失マウス / GCbox配列 / ターゲティングベクター / knockout mice / POZ domain / BTB domain / transcription factor / chromatin / Maf / 細胞分化 / インスレーター / POZドメイン / BTBドメイン / クロマチン / Transgenic mice / Knockout mice / Erythroid cells / モデル動物 / 赤血球分化 / 環状鉄芽球 / 鉄代謝 / 鉄芽球性貧血 / 遺伝子改変マウス / ヘム生合成 / トランスジェニックマウス / 赤血球系細胞 / Heme-oxygenase 1 / Transcription / MafK / NF-E2 / コプロポルフィリノーゲンオキシダーゼ / ヘムオキシゲナーゼ / ヘム調節モチーフ / ヘム生合成調節 / ヘムオキシゲナーゼ1 / 転写 / c-Kit陽性骨髄造血前駆細胞 / マイクロアレイ法 / OP9ストローマ細胞 / 細胞分化方向性 / 転写制御 / 胎児造血幹細胞 / 自己複製能維持 / 遺伝子導入マウス / 白血病細胞 / 選択的プロモーター / 造血細胞特異的エンハンサー / GATA-2 Less

Elucidation of the mechanism of growth of refractory pancreatic cancer and development of new therapeutic strategies.Principal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Doshisha University
Physiological function of arginine signaling:macropinocytosisand tumor immune evasionPrincipal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Doshisha University
腫瘍免疫系における転写因子NRF3を介した肥満パラドックスの分子メカニズム解明
- Principal Investigator
  
  和久剛
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Doshisha University
Investigation of molecular mechanisms underlying selective autophagy activation upon proteasome dysfunctionPrincipal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Doshisha University
Improvement of immune checkpoint inhibition therapy for the treatment of pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  Kobayashi Akira
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Doshisha University
Elucidation of novel physiological effects of amino acid signaling and its mediated lifespan extension and immune exhaustPrincipal Investigator
- Principal Investigator
  
  Kobayashi Akira
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Doshisha University
Pathophysiological role of NRF3-mediated protein degradation in colorectal cancer development
- Principal Investigator
  
  Waku Tsuyoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Doshisha University
Examination of coupled gene expression mechanisms of proteasome for anti-agingPrincipal Investigator
- Principal Investigator
  
  Kobayashi Akira
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Doshisha University
Molecular analysis of the proteasome gene expression and its application to anti-aging.Principal Investigator
- Principal Investigator
  
  KOBAYASHI AKIRA
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied health science
- Research Institution
  Doshisha University
脂肪滴を介した新たな転写代謝システムの解明Principal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Doshisha University
Advanced investigation of molecular regulation of lipid metabolism by the transcription factor Nrf1Principal Investigator
- Principal Investigator
  
  KOBAYASHI Akira
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Doshisha University
タンパク質分解制御による酸化ストレス応答機構の解明Principal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Doshisha University
  Tohoku University
酸化ストレスセンサーKeap1のストレス応答機構Principal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Doshisha University
  Tohoku University
Physiological roles of the transcription factor Nrf1 on the lipid metabolismPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Akira
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Doshisha University
  Tohoku University
Stress sensing and protein degradation mechanism of oxidative stress sensor KeaplPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Akira
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
  University of Tsukuba
分化方向性の制御から挑む再生医工学
- Principal Investigator
  
  YAMAMOTO Masayuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  University of Tsukuba
転写因子Nrf3の腫瘍とapoptosis誘導における機能解析Principal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Functional analysis of BTEB and BTEB2 transcription factors by gene-targeting technology
- Principal Investigator
  
  FUJII Yoshiaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  University of Tsukuba
  Tohoku University
転写因子Nrf3の大腸癌とapoptosis誘導における機能解析Principal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
Regulation of chromatin structures during hematopoietic cell differentiation
- Principal Investigator
  
  IGARASHI Kazuhiko
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General medical chemistry
- Research Institution
  HIROSHIMA UNIVERSITY
Functional analyses of the CNC transcription factor Nrf3 in colon cancer and T cell developmentPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Akira
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
NF-E2関連因子群によるクロマチン構造の制御と造血細胞分化における転写制御機構Principal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
造血細胞分化におけるNF-E2関連因子群の機能Principal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
白血病細胞における転写因子GATA-2の転写調節機構の解析
- Principal Investigator
  
  HAYASHI Norio
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Tohoku University
NF-E2結合配列を介した転写調節機構とその血液細胞分化における役割Principal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tohoku University
新たなCNCファミリー因子Nrf3の機能解析Principal Investigator
- Principal Investigator
  
  小林聡
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Tohoku University
Roles of heme in the regulation of gene expression and cell differentiation of erythroid cells
- Principal Investigator
  
  HAYASHI Norio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku University
Gene manipulation of heme synthetic pathway enzymes
- Principal Investigator
  
  HAYASHI Norio
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tohoku University

[Book] 南山堂医学大事典2015
- Author(s)
  小林聡、他
- Total Pages
  1
- Publisher
  南山堂
- Data Source
  KAKENHI-PUBLICLY-26116725
[Book] プロテアソームリカバリーにおける転写因子Nrf1 (NFE2L1)の遺伝子発現機構2014
- Author(s)
  小林聡、土谷佳樹
- Total Pages
  4
- Publisher
  日本生化学会
- Data Source
  KAKENHI-PUBLICLY-26116725
[Book] 酸化ストレスの医学2008
- Author(s)
  小林聡
- Total Pages
  384
- Publisher
  Keapl-Nrf2システムによる酸化ストレス・親電子性物質応答機構
- Data Source
  KAKENHI-PROJECT-19590268
[Book] Keap1-Nrf2システムによる酸化ストレス・親電子性物質応答機構(『酸化ストレスの医学』所収)2008
- Author(s)
  小林聡
- Total Pages
  384
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-19045005
[Book] Keap1-Nrf2システムによる酸化ストレス・親電子性物質応答機構(『酸化ストレスの医学』所収)2008
- Author(s)
  小林聡
- Total Pages
  384
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-19044006
[Book] 診断と治療社「Keap1-Nrf2システムによる酸化ストレス・親電子性物質応答機構」, 酸化ストレスの医学2008
- Author(s)
  小林聡、山本雅之
- Data Source
  KAKENHI-PROJECT-19590268
[Book] ユビキチン-プロテアソーム系とオートファジ-2006
- Author(s)
  小林聡, キットトン
- Total Pages
  1556
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-17590238
[Book] ユビキチンープロテアソーム系とオートファジー2006
- Author(s)
  小林聡, キットトン
- Total Pages
  1556
- Publisher
  共立出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590238
[Journal Article] The CNC-family transcription factor Nrf3 coordinates the melanogenesis cascade through macropinocytosis and autophagy regulation2023
- Author(s)
  Waku Tsuyoshi、Nakada Sota、Masuda Haruka、Sumi Haruna、Wada Ayaka、Hirose Shuuhei、Aketa Iori、Kobayashi Akira
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 1 Pages: 111906-111906
- DOI
  10.1016/j.celrep.2022.111906
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07219, KAKENHI-PROJECT-20H04135, KAKENHI-PROJECT-20J20194, KAKENHI-PROJECT-21K19743, KAKENHI-PUBLICLY-22H04659
[Journal Article] The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis2023
- Author(s)
  Hatanaka Atsushi、Nakada Sota、Matsumoto Gen、Satoh Katsuya、Aketa Iori、Watanabe Akira、Hirakawa Tomoaki、Tsujita Tadayuki、Waku Tsuyoshi、Kobayashi Akira
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 14405-14405
- DOI
  10.1038/s41598-023-41492-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07417, KAKENHI-PUBLICLY-22H04651, KAKENHI-PUBLICLY-22H04659, KAKENHI-PROJECT-23K24214, KAKENHI-PROJECT-23K24772, KAKENHI-PROJECT-23K28007
[Journal Article] NRF3 activates mTORC1 arginine-dependently for cancer cell viability2023
- Author(s)
  Hirose Shuuhei、Waku Tsuyoshi、Tani Misato、Masuda Haruka、Endo Keiko、Ashitani Sanae、Aketa Iori、Kitano Hina、Nakada Sota、Wada Ayaka、Hatanaka Atsushi、Osawa Tsuyoshi、Soga Tomoyoshi、Kobayashi Akira
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 2 Pages: 106045-106045
- DOI
  10.1016/j.isci.2023.106045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07219, KAKENHI-PROJECT-19H03496, KAKENHI-PROJECT-20H04135, KAKENHI-PROJECT-20J20194, KAKENHI-PROJECT-21K19399, KAKENHI-PROJECT-21K19743, KAKENHI-PUBLICLY-22H04659, KAKENHI-PROJECT-23K18234, KAKENHI-PROJECT-22H04925
[Journal Article] Nrf3 Functions Reversely as a Tumorigenic to an Antitumorigenic Transcription Factor in Obese Mice2023
- Author(s)
  Waku Tsuyoshi、Iwami Takuya、Masuda Haruka、Hirose Shuuhei、Aketa Iori、Kobayashi Akira
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 259 Issue: 1 Pages: 1-8
- DOI
  10.1620/tjem.2022.J090
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07219, KAKENHI-PROJECT-20H04135, KAKENHI-PROJECT-20J20194, KAKENHI-PROJECT-21K19743, KAKENHI-PUBLICLY-22H04659
[Journal Article] NRF3 upregulates gene expression in SREBP2-dependent mevalonate pathway with cholesterol uptake and lipogenesis inhibition2021
- Author(s)
  Waku Tsuyoshi、Hagiwara Toru、Tamura Natsuko、Atsumi Yuri、Urano Yasuomi、Suzuki Mikiko、Iwami Takuya、Sato Katsuya、Yamamoto Masayuki、Noguchi Noriko、Kobayashi Akira
- Journal Title
  
  iScience
  
  Volume: 24 Issue: 10 Pages: 103180-103180
- DOI
  10.1016/j.isci.2021.103180
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07093, KAKENHI-PROJECT-19K07650, KAKENHI-PROJECT-20H04135, KAKENHI-PROJECT-21K19743, KAKENHI-PROJECT-23K20318
[Journal Article] Pathophysiological Potentials of NRF3-Regulated Transcriptional Axes in Protein and Lipid Homeostasis2021
- Author(s)
  Waku Tsuyoshi、Kobayashi Akira
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 23 Pages: 12686-12686
- DOI
  10.3390/ijms222312686
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07650, KAKENHI-PROJECT-20H04135, KAKENHI-PROJECT-21K19743, KAKENHI-PROJECT-23K20318
[Journal Article] New addiction to the NRF2-related factor NRF3 in cancer cells: Ubiquitin-independent proteolysis through the 20S proteasome.2020
- Author(s)
  Kobayashi A, Waku T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 111 Issue: 1 Pages: 6-14
- DOI
  10.1111/cas.14244
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07650, KAKENHI-PROJECT-19K22826, KAKENHI-PROJECT-20H04135
[Journal Article] NRF3-POMP-20S proteasome assembly axis promotes cancer development via ubiquitin-independent proteolysis of p53 and Rb.2020
- Author(s)
  Waku T, Nakamura N, Koji M, Watanabe H, Katoh H, Tatsumi C, Tamura N, Hatanaka A, Hirose S, Katayama H, Tani M, Kubo Y, Hamazaki J, Hamakubo T, Watanabe A, Murata S, Kobayashi A
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: - Issue: 10 Pages: 1-1
- DOI
  10.1128/mcb.00597-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07062, KAKENHI-PROJECT-19K07650, KAKENHI-PROJECT-19K22826, KAKENHI-PROJECT-18J20672, KAKENHI-PLANNED-18H05500, KAKENHI-PROJECT-18H04022, KAKENHI-PROJECT-20H04135, KAKENHI-ORGANIZER-18H05497
[Journal Article] NFE2L1 and NFE2L3 complementarily maintain basal proteasome activity in cancer cells through CPEB3-mediated translational repression2020
- Author(s)
  Waku, T., Katayama, H., Hiraoka, M., Hatanaka, A., Nakamura, N., Tanaka, Y., Tamura, N., Watanabe, A., and Kobayashi, A.
- Journal Title
  
  Molecular and cellular biology
  
  Volume: 40 Issue: 14
- DOI
  10.1128/mcb.00010-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04135, KAKENHI-PROJECT-18J20672, KAKENHI-PROJECT-19K22826, KAKENHI-PROJECT-19K07650
[Journal Article] Roles of NRF3 in the hallmarks of cancer: proteasomal inactivation of tumor suppressors.2020
- Author(s)
  Kobayashi, A
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 9 Pages: 2681-2681
- DOI
  10.3390/cancers12092681
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04135, KAKENHI-PROJECT-19K22826
[Journal Article] β-Catenin/TCF4 Complex-Mediated Induction of the NRF3 (NFE2L3) Gene in Cancer Cells.2019
- Author(s)
  Aono S, Hatanaka A, Hatanaka A, Gao Y, Hippo Y, Taketo MM, Waku T, Kobayashi A.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 20 Issue: 13 Pages: 3344-3344
- DOI
  10.3390/ijms20133344
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07650, KAKENHI-PROJECT-19K22826, KAKENHI-PROJECT-18J20672, KAKENHI-PROJECT-17K19624
[Journal Article] O-GlcNAcylation Signal Mediates Proteasome Inhibitor Resistance in Cancer Cells by Stabilizing NRF12018
- Author(s)
  Sekine Hiroki、Okazaki Keito、Kato Koichiro、Alam M. Morshedul、Shima Hiroki、Katsuoka Fumiki、Tsujita Tadayuki、Suzuki Norio、Kobayashi Akira、Igarashi Kazuhiko、Yamamoto Masayuki、Motohashi Hozumi
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 38 Issue: 17 Pages: 00252-18
- DOI
  10.1128/mcb.00252-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07278, KAKENHI-PROJECT-17K19680, KAKENHI-PROJECT-17K19916, KAKENHI-PUBLICLY-18H04794, KAKENHI-PROJECT-18H04021, KAKENHI-PROJECT-15H04691, KAKENHI-PROJECT-16H03265, KAKENHI-PROJECT-18H02621, KAKENHI-PROJECT-16H05922, KAKENHI-PROJECT-17F17116, KAKENHI-PROJECT-17K19508, KAKENHI-PROJECT-17K08618
[Journal Article] The cysteine-rich domain of TET2 binds preferentially to mono- and dimethylated histone H3K362017
- Author(s)
  Yamagata, K., and Kobayashi, A.
- Journal Title
  
  J Biochem.
  
  Volume: 4 Pages: 327-330
- DOI
  10.1093/jb/mvx004
- NAID
  40021219779
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K19206, KAKENHI-PROJECT-16H03265
[Journal Article] Multiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation2017
- Author(s)
  Chowdhury A. M. Masudul Azad、Katoh Hiroki、Hatanaka Atsushi、Iwanari Hiroko、Nakamura Nanami、Hamakubo Takao、Natsume Tohru、Waku Tsuyoshi、Kobayashi Akira
- Journal Title
  
  Scientific reports
  
  Volume: 7 Issue: 1 Pages: 1-14
- DOI
  10.1038/s41598-017-12675-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K18234, KAKENHI-PROJECT-16H03265
[Journal Article] Possible roles of the transcription factor Nrf1 (NFE2L1) in neural homeostasis by regulating the gene expression of deubiquitinating enzymes.2017
- Author(s)
  Taniguchi, H., Okamuro, S., Kohji, M., Waku, T., Kubo, K., Hatanaka, A., Sun, Y., A M Chowdhury, AM A., Fukamizu, A., Kobayashi, A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 484 Issue: 1 Pages: 176-183
- DOI
  10.1016/j.bbrc.2017.01.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H03265
[Journal Article] Denaturation of DNA in ternary mixed solution of water/hydrophilic/hydrophobic organic solvent.2017
- Author(s)
  Ito Y. Tsukagoshi K, Kobayashi A.
- Journal Title
  
  J Anal Sci, Method Instrum.
  
  Volume: 7 Issue: 02 Pages: 40-46
- DOI
  10.4236/jasmi.2017.72004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H03265, KAKENHI-PROJECT-17H03083
[Journal Article] USP15 stabilizes the transcription factor Nrf1 in the nucleus, promoting the proteasome gene expression.2016
- Author(s)
  Fukagai, K., Waku, T., Chowdhury, AM., Kubo, K., Matsumoto, M., Kato, H., Natsume, T., Tsuruta, F., Chiba, T., Taniguchi, H., Kobayashi, A.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 478 Issue: 1 Pages: 363-370
- DOI
  10.1016/j.bbrc.2016.07.045
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H03265, KAKENHI-PROJECT-16K07339
[Journal Article] NML-mediated rRNA base methylation links ribosomal subunit formation to cell proliferation in a p53-dependent manner.2016
- Author(s)
  Waku T., Nakajima Y., Yokoyama W., Nomura N., Kako K., Kobayashi A., Shimizu T., and Fukamizu A.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 129 Issue: 12 Pages: 2382-2393
- DOI
  10.1242/jcs.183723
- NAID
  120007129526
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-WRAPUP-16H01688, KAKENHI-PROJECT-16H03265, KAKENHI-PROJECT-26350957
[Journal Article] Constitutive activation of Drosophila CncC transcription factor reduces lipid formation in the fat body.2015
- Author(s)
  Karim, MR., Taniguchi, H., Kobayashi, A.
- Journal Title
  
  Biochem. Biophys. Res. Com.
  
  Volume: 463 Issue: 4 Pages: 693-698
- DOI
  10.1016/j.bbrc.2015.05.126
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26116725
[Journal Article] Inhibitory mechanism of FAT4 gene expression in response to actin dynamics during Src-induced carcinogenesis.2015
- Author(s)
  Ito, T., Taniguchi, H., Fukagai, K., Okamuro, S. and Kobayashi, A.
- Journal Title
  
  PLOS ONE
  
  Volume: 10 Issue: 2 Pages: e0118336-e0118336
- DOI
  10.1371/journal.pone.0118336
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26116725
[Journal Article] Dual regulation of the transcriptional activity of Nrf1 by β-TrCP-and Hrd1-dependent degradation mechanisms2011
- Author(s)
  Tsuchiya, Y., Morita, T., Kim, M., Iemura, S., Natsume, T., Yamamoto, M. and Kobayashi, A.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: 31 Pages: 4500-4512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590277
[Journal Article] Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction2011
- Author(s)
  Kobayashi, A., Tsukide, T., Miyasaka, T., Morita, T., Mizoroki, T., Saito, Y., Ihara, Y., Takashima, A., Noguchi, N., Fukamizu, A., Hirotsu, Y., Ohtsuji, M., Katsuoka, F. and Yamamoto, M.
- Journal Title
  
  Genes Cells
  
  Volume: 16 Pages: 692-703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590277
[Journal Article] Central nervous system-specific deletion of transcription factor Nrf1 causes progressive motor neuronal dysfunction2011
- Author(s)
  Kobayashi A, Tsukide T, Miyasaka T, Morita T, Mizoroki T, Saito Y, Ihara Y, Takashima A, Noguchi N, Fukamizu A, Hirotsu Y, Ohtsuji M, Katsuoka F, Yamamoto M
- Journal Title
  
  Genes Cells
  
  Volume: 16 Issue: 6 Pages: 692-703
- DOI
  10.1111/j.1365-2443.2011.01522.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19GS0312, KAKENHI-PROJECT-22590277
[Journal Article] Structural insights into the similar modes of Nrf2 transcription factor recognition by the cytoplasmic repressor Keap12008
- Author(s)
  Padmanabhan, B., Tong, KI., Kobayashi, A., Yamamoto, M., and Yokoyama S.
- Journal Title
  
  J Synchrotron Radiat 15(Pt 3)
  
  Pages: 273-276
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590268
[Journal Article] Loss of Keap1 function activates Nrf2 and provides advantages for lungcancer cell growth.2008
- Author(s)
  Ohta, T., Iijima, K., Miyamoto, M., Nakahara, I., Tanaka, H., Ohtsuji, M., Suzuki, T., Kobayashi, A., Yokota, J., Sakiyama, T., Shibata, T., Yamamoto, M., Hirohashi, S.
- Journal Title
  
  Cancer Res 68
  
  Pages: 1303-1309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590268
[Journal Article] Keap1 regulates the constitutive expression of GST A1 during differentiation of Caco-2 cells2008
- Author(s)
  Kusano, Y., Horie, S., Shibata, T., Satsu, H., Shimizu, M., Hitomi, E., Nishida, M., Kurose, H., Itoh, K., Kobayashi, A., Yamamoto, M. and Uchida, K.
- Journal Title
  
  Biochemistry 47
  
  Pages: 6169-6177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590268
[Journal Article] Carnosic acid, a catechol-type electrophilic compound, protects neurons both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of targeted cysteines on Keap12008
- Author(s)
  Satoh, T., Kosaka, K., Itoh, K., Kobayashi, A., Yamamoto, M., Shimojo, Y., Kitajima, C., Cui, J., Kamins, J., Okamoto, S., Izumi, M., Shirasawa, T. and Lipton, SA.
- Journal Title
  
  J. Neurochem 104
  
  Pages: 1116-1131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590268
[Journal Article] Hepatocyte-specific deletion of heme oxygenase-1 disrupts redox homeostasis in Basal and oxidative environments2008
- Author(s)
  Mamiya, T., Katsuoka, F., Hirayama, A., Nakajima, O., Kobayashi, A., Maher, J. M., Matsui, H., Hyodo, I. and Yamamoto M, and Hosoya, T.
- Journal Title
  
  Tohoku J Exp Med 216
  
  Pages: 331-339
- NAID
  10025104347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590268
[Journal Article] Physiological Significance of Reactive Cysteine Residues of Keap1 in Determining Nrf2 Activity2008
- Author(s)
  Yamamoto, T., Suzuki, T., Kobayashi, A., Wakabayashi, J., Maher, J., Motohashi, H., and Yamamoto, M.
- Journal Title
  
  Mol. Cell. Biol 28
  
  Pages: 2758-2770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590268
[Journal Article] Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes.2008
- Author(s)
  Ohtsuji, M., Katsuoka, F., Kobayashi, A., Aburatani, H., Hayes, J. D. and Yamamoto, M.
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 33554-33562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590268
[Journal Article] Oxidative and Electrophilic Stresses Activate Nrf2 through inhibition of Ubiquitination Activity of Keap12006
- Author(s)
  Kobayashi, A.et al.
- Journal Title
  
  Mol.Cell Biol 26
  
  Pages: 221-229
- Data Source
  KAKENHI-PROJECT-17590238
[Journal Article] Oxidative and Electrophilic Stresses Activate Nrf2 through Inhibition of Ubiquitination Activity of Keapl.2006
- Author(s)
  Kobayashi, A. et al.
- Journal Title
  
  Mol. Cell Biol. 26
  
  Pages: 221-229
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590238
[Journal Article] Ubiquitin-Proteasome system ＆ autophagy2006
- Author(s)
  Kobayashi, A. et al.
- Journal Title
  
  kyoritsu-syuppan 1556
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590238
[Journal Article] Oxidative and Electrophilic Stresses Activate Nrf2 through Inhibition of Ubiquitination Activity of Keap1.2006
- Author(s)
  kobayashi, A., et al.
- Journal Title
  
  Mol.Cell Biol. 26
  
  Pages: 221-229
- Data Source
  KAKENHI-PROJECT-17590238
[Journal Article] Oxidative and Electrophilic Stresses Activate Nrf2 through Inhibition of Ubiquitination Activity of Keap12006
- Author(s)
  Kobayashi, A. et al.
- Journal Title
  
  Mol. Cell Biol. 26
  
  Pages: 221-229
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590238
[Journal Article] Molecular cloning and functional characterization of a new CNC family transcription factor Nrf3.1999
- Author(s)
  Kobayashi, A., Itoh, E., Toki, T., Takahashi, S-i, Igarashi, K., Hayashi, N., Yamamoto, M.
- Journal Title
  
  J. Biol. Chem. 274
  
  Pages: 6443-6452
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-10557015
[Journal Article] Molecular cloning and functional characterization of a new CNC family transcription factor Nrf31999
- Author(s)
  Kobayashi, A., Itoh, E., Toki, T., Takahashi, S-i, Igarashi, K., Hayashi, N., Yamamoto, M.
- Journal Title
  
  J.Biol.Chem. 274
  
  Pages: 6443-6452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-10480163
[Journal Article] Molecular cloning and functional characterization of a new CNC family transcription factor Nrf31999
- Author(s)
  Kobayashi, A., Itoh, E., Toki, T., Takahashi, S-i, Igarashi, K., Hayashi, N., Yamamoto, M.
- Journal Title
  
  J.Biol.Chem. 274
  
  Pages: 6443-6452
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-10557015
[Journal Article] Molecular cloning and functional characterization of a new CNC family transcription factor Nrf3.1999
- Author(s)
  Kobayashi, A., Itoh, E., Toki, T., Takahashi, S-i, Igarashi, K., Hayashi, N., Yamamoto, M.
- Journal Title
  
  J. Biol. Chem. 274
  
  Pages: 6443-6452
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-10480163
[Journal Article] Differential regulation of mouse coproporphyrinogen oxidase geneexpression in erythroid and non-erythroid cells.1998
- Author(s)
  Takahashi, S-i., Taketani, S., Akasaka, J-e., Kobayashi, A., Hayashi, N., Yamamoto, M., Nagai, T.
- Journal Title
  
  Blood 92
  
  Pages: 3436-3444
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-10557015
[Journal Article] Differential regulation of mouse coproporphyrinogen oxidase gene expression in erythroid and non-erythroid cells1998
- Author(s)
  Takahashi, S-i., Taketani, S., Akasaka, J-e., Kobayashi, A., Hayashi, N., Yamamoto, M., Nagai, T.
- Journal Title
  
  Blood 92
  
  Pages: 3436-3444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-10557015
[Journal Article] Differential regulation of mouse coproporphyrinogen oxidase geneexpression in erythroid and non-erythroid cells.1998
- Author(s)
  Takahashi, S-i., Taketani, S., Akasaka, J-e., Kobayashi, A., Hayashi, N., Yamamoto, M., Nagai, T.
- Journal Title
  
  Blood 92
  
  Pages: 3436-3444
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-10480163
[Journal Article] Differential regulation of mouse coproporphyrinogen oxidase gene expression in erythroid and non-erythroid cells1998
- Author(s)
  Takahashi, S-i., Taketani, S., Akasaka, J-e., Kobayashi, A., Hayashi, N., Yamamoto, M., Nagai, T.
- Journal Title
  
  Blood 92
  
  Pages: 3436-3444
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-10480163
[Journal Article] Different electrostatic potentials define ETGE and DLG motifs ashinge and latch in oxidative stress response
- Author(s)
  Tong, K.I., Padmanabhan, B., Kobayashi, A., Shang, C., Hirotsu, H., Yokoyama, S. and Yamamoto, M.
- Journal Title
  
  Mol. Cell. Biol 21
  
  Pages: 7511-7521
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590268
[Journal Article] Subcellular Localization and Cytoplasmic Complex Status of Endogenous Keap1
- Author(s)
  Watai, Y., *Kobayashi, A., Nagase, H., Mizukami, M., McEvoy, J., Singer, J.D., Itoh, K., and *Yamamoto, M.
- Journal Title
  
  Genes to Cells 12
  
  Pages: 1163-1178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590268
[Journal Article] Loss of p62/SQSTM1 Suppresses Cytoplasmic Inclusion Body Formation and Liver Injury in Autophagy-Deficient Mouse.
- Author(s)
  Komatsu, M., Waguri, S., Koike, M., Sou, Y.-S., Ueno, T., Hara, T., Mizushima, N., Iwata, J., Ezaki, J., Murata, S., Hamazaki, J., Nishito, Y., Iemura, S., Natsume, T., Yanagawa, T., Uwayama, J., Warabi, E., Yoshida, H., Ishii, T., Kobayashi, A., Yamamoto, M., Yue, Z., Uchiyama, Y., Kominami, E. and Tanaka, K.
- Journal Title
  
  Cell 131
  
  Pages: 1149-1163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590268
[Journal Article] Protein S-guanylation by the biological signal 8-nitroguanosine 3', 5'-cyclic monophosphate
- Author(s)
  Sawa, T., Zaki, M.H., Okamoto, T., Akuta, T., Tokutomi, Y., Kim-Mitsuyama, S., Ihara, H. Kobayashi, A., Yamamoto, M., Fujii, S., Arimoto, H. and Akaike, T.
- Journal Title
  
  Nature Chem. Biol 11
  
  Pages: 727-735
- NAID
  120002467822
- Data Source
  KAKENHI-PROJECT-19590268
[Patent] 抗がん剤2017
- Inventor(s)
  和久剛、小林聡、加藤裕紀、糀美早紀、渡辺秀教
- Industrial Property Rights Holder
  和久剛、小林聡、加藤裕紀、糀美早紀、渡辺秀教
- Industrial Property Rights Type
  特許
- Filing Date
  2017-03-15
- Overseas
- Data Source
  KAKENHI-PROJECT-16H03265
[Patent] 抗HIV治療薬を利用した抗がん剤2017
- Inventor(s)
  和久剛、小林聡、畠中惇至
- Industrial Property Rights Holder
  和久剛、小林聡、畠中惇至
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-087470
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16H03265
[Patent] 細胞抽出装置、細胞抽出プログラム及び細胞抽出方法2017
- Inventor(s)
  廣安知之、和久剛、日和悟、小林聡、藤井光央、廣瀬修平
- Industrial Property Rights Holder
  廣安知之、和久剛、日和悟、小林聡、藤井光央、廣瀬修平
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-236063
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-16H03265
[Patent] 抗がん剤2016
- Inventor(s)
  和久剛、小林聡、渡辺秀教
- Industrial Property Rights Holder
  和久剛、小林聡、渡辺秀教
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-051934
- Filing Date
  2016-03-16
- Data Source
  KAKENHI-PUBLICLY-26116725
[Patent] 抗がん剤2016
- Inventor(s)
  和久剛、小林聡、加藤裕紀、渡辺秀教
- Industrial Property Rights Holder
  和久剛、小林聡、加藤裕紀、渡辺秀教
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-230449
- Filing Date
  2016-11-28
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] NRF2-related NRF3 activates mTORC1 signaling in response to diminished arginine levels in cancer.2023
- Author(s)
  Kobayashi A
- Organizer
  The Environmental Response VI
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] 膵臓の腫瘍悪性化機構の解明に向けた転写因子NRF3の機能解析2023
- Author(s)
  佐藤克哉、山元康平、〇佐藤健、道原琢登、浅野太我、河合穂高、江口傑徳、松本光代、五十嵐和彦、和久剛、小林聡
- Organizer
  第69回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-23K28007
[Presentation] The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis.2023
- Author(s)
  Hatanaka A, Nakada S, Matsumoto G, Satoh K, Aketa I, Watanabe A, Hirakawa T, Tsujita T, Waku T, Kobayashi A.
- Organizer
  The Environmental Response VI
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28007
[Presentation] 転写因子NRF3によるMHC-Iのオートファジー分解を介した腫瘍免疫抑制メカニズム解析2023
- Author(s)
  温品美綺、和田恵佳、牧野安優花、明田伊鳳、廣瀬修平、和久剛、小林聡
- Organizer
  第５回マルチモードオートファジー班会議
- Data Source
  KAKENHI-PROJECT-23K28007
[Presentation] NRF2-related NRF3 activates mTORC1 signaling in response to diminished arginine levels in cancer.2023
- Author(s)
  Kobayashi A.
- Organizer
  The Environmental Response VI
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28007
[Presentation] Functional analysis of NRF2-related factor NRF3 in pancreatic tumor growth and malignancy.2023
- Author(s)
  Satoh K, Michihara T, Yamamoto K, Sato K, Matsumoto M, Igarashi K, Waku T, Kobayashi A.
- Organizer
  The Environmental Response VI
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] 転写因子NRF3はオートファジーを介してがん細胞のMHC-Iを分解する2023
- Author(s)
  温品美綺、和田恵佳、明田伊鳳、廣瀬修平、和久剛、小林聡
- Organizer
  第69回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-23K28007
[Presentation] 転写因子NRF3によるMHC-Iのオートファジー分解を介した腫瘍免疫抑制メカニズム解析2023
- Author(s)
  温品美綺、和田恵佳、牧野安優花、明田伊鳳、廣瀬修平、和久剛、小林聡
- Organizer
  第５回マルチモードオートファジー班会議
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] 転写因子Nrf3によるオートファジー-MHC-I分解経路を介したがん免疫逃避メカニズムの解明2023
- Author(s)
  温品美綺、和田恵佳、明田伊鳳、廣瀬修平、牧野安優花、和久剛、小林聡
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K28007
[Presentation] 膵臓の腫瘍悪性化機構の解明に向けた転写因子NRF3の機能解析2023
- Author(s)
  佐藤克哉、山元康平、〇佐藤健、道原琢登、浅野太我、河合穂高、江口傑徳、松本光代、五十嵐和彦、和久剛、小林聡
- Organizer
  第69回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] The transcription factor NRF1 (NFE2L1) activates aggrephagy by inducing p62 and GABARAPL1 after proteasome inhibition to maintain proteostasis.2023
- Author(s)
  Hatanaka A, Nakada S, Matsumoto G, Satoh K, Aketa I, Watanabe A, Hirakawa T, Tsujita T, Waku T, Kobayashi A.
- Organizer
  The Environmental Response VI
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] 膵臓がんにおける新たな腫瘍増大因子としての転写因子NRF3の機能解析2023
- Author(s)
  佐藤克哉、道原琢登、山元康平、佐藤健、松本光代、五十嵐和彦、和久剛、小林聡
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] The NRF2-related transcription factor NRF3 protects pancreatic cancer cells from ferroptosis by inducing the expression of redox-related genes.2023
- Author(s)
  Shi TY, Hatanaka A, Minase M, 〇Soga K, Sato K, Hatanaka A, Satoh K, Yamamoto K, Nishikawa K, Waku T, Kobayashi A.
- Organizer
  The Environmental Response VI
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28007
[Presentation] The NRF2-related transcription factor NRF3 protects pancreatic cancer cells from ferroptosis by inducing the expression of redox-related genes.2023
- Author(s)
  Shi TY, Hatanaka A, Minase M, 〇Soga K, Sato K, Hatanaka A, Satoh K, Yamamoto K, Nishikawa K, Waku T, Kobayashi A.
- Organizer
  The Environmental Response VI
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] Functional analysis of NRF2-related factor NRF3 in pancreatic tumor growth and malignancy.2023
- Author(s)
  Satoh K, Michihara T, Yamamoto K, Sato K, Matsumoto M, Igarashi K, Waku T, Kobayashi A.
- Organizer
  The Environmental Response VI
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28007
[Presentation] 転写因子NRF3によるMHC-Iのオートファジー分解を介した腫瘍免疫抑制メカニズム解析2023
- Author(s)
  温品美綺、和田恵佳、牧野安優花、明田伊鳳、廣瀬修平、和久剛、小林聡
- Organizer
  第1５回オートファジー研究会若手の会
- Data Source
  KAKENHI-PROJECT-23K28007
[Presentation] 転写因子Nrf3によるオートファジー-MHC-I分解経路を介したがん免疫逃避メカニズムの解明2023
- Author(s)
  温品美綺、和田恵佳、明田伊鳳、廣瀬修平、牧野安優花、和久剛、小林聡
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] 転写因子NRF3はオートファジーを介してがん細胞のMHC-Iを分解する2023
- Author(s)
  温品美綺、和田恵佳、牧野安優花、明田伊鳳、廣瀬修平、和久剛、小林聡
- Organizer
  第69回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] 膵臓がんにおける新たな腫瘍増大因子としての転写因子NRF3の機能解析2023
- Author(s)
  佐藤克哉、道原琢登、山元康平、佐藤健、松本光代、五十嵐和彦、和久剛、小林聡
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K28007
[Presentation] 転写因子NRF3はオートファジーを介してがん細胞のMHC-Iを分解する2023
- Author(s)
  温品美綺、和田恵佳、牧野安優花、明田伊鳳、廣瀬修平、和久剛、小林聡
- Organizer
  第1５回オートファジー研究会若手の会
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] Identification of Pathological Function of the NRF3-CTGF Axis in Pancreatic Cancer Malignancies.2022
- Author(s)
  Takuto Michihara, 〇Katsuya Satoh, Kohei Yamamoto, Yue Gao, Tsuyoshi Waku, Akira Kobayashi
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] A transcription factor NRF1(NFE2L1) activates selective autophagy by inducing p62 and GABARAPL1 expression upon proteasome inhibition.2022
- Author(s)
  Atsushi Hatanaka, Sota Nakada, Iori Aketa, Katsuya Satoh, Gen Matsumoto, Akira Watanabe, Tomofumi Yoshida, Shigeo Takamori, Tsuyoshi Waku, Akira Kobayashi
- Organizer
  The 10th International Symposium on Autophagy (ISA2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] 転写因子Nrf3は細胞膜輸送系の制御を介してメラニン産生カスケードを最適化する2022
- Author(s)
  和田恵佳、中田創太、増田　遥、住春　菜、和久剛、小林　聡
- Organizer
  第68回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] 膵臓がんのシステイン依存性におけるNRF3-xCT経路の機能2022
- Author(s)
  史　天宇、畑中彩里、水瀬雅己、和久　剛、小林　聡
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] NRF3はアルギニンによるmTORC1活性化を介して腫瘍を増大させる2022
- Author(s)
  廣瀬修平、和久　剛、増田　遥、明田伊鳳、畠中敦至、大澤　毅、曽我朋義、小林　聡
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] 膵臓がんのシステイン依存性におけるNRF3-xCT経路の機能2022
- Author(s)
  史　天宇、畑中彩里、水瀬雅己、和久　剛、小林　聡
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] 転写因子Nrf3は細胞膜輸送系の制御を介してメラニン産生カスケードを最適化する2022
- Author(s)
  和田恵佳、中田創太、増田　遥、住　春菜、廣瀬修平、明田伊鳳、和久　剛、小林　聡
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] NRF3-CCN2経路による膵臓の新たな悪性化機構2022
- Author(s)
  小林　聡
- Organizer
  第13回日本CCNファミリー研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] プロテオスタシスないしアルギニン欠乏シグナルに対する新たな生体応答2022
- Author(s)
  小林　聡
- Organizer
  第16回日本臨床ストレス応答学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] 転写因子Nrf3は細胞膜輸送系の制御を介してメラニン産生カスケードを最適化する2022
- Author(s)
  和田恵佳、中田創太、増田　遥、住　春菜、廣瀬修平、明田伊鳳、和久　剛、小林　聡
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] 転写因子Nrf3は細胞膜輸送系の制御を介してメラニン産生カスケードを最適化する2022
- Author(s)
  和田恵佳、中田創太、増田　遥、住春　菜、和久剛、小林　聡
- Organizer
  第68回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] がん微小環境におけるオーファン転写因子NRF3のアルギニンを介した新たな腫瘍増大機構2022
- Author(s)
  小林　聡
- Organizer
  佐賀大学農学部生化学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF3-CCN2経路による膵臓の新たな悪性化機構2022
- Author(s)
  小林　聡
- Organizer
  第13回日本CCNファミリー研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] 転写因子NRF3によるミトコンドリア動態制御の可能性2022
- Author(s)
  明田伊鳳、廣瀬修平、増田　遥、和田恵佳、佐藤清敏、曽我朋義、和久　剛、小林　聡
- Organizer
  第68回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] Identification of Pathological Function of the NRF3-CTGF Axis in Pancreatic Cancer Malignancies.2022
- Author(s)
  Takuto Michihara, Katsuya Satoh, Kohei Yamamoto, Yue Gao, Tsuyoshi Waku, Akira Kobayashi
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] プロテオスタシスないしアルギニン欠乏シグナルに対する新たな生体応答2022
- Author(s)
  小林　聡
- Organizer
  第16回日本臨床ストレス応答学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] 膵臓がんのシステイン依存性におけるNRF3-xCT経路の機能2022
- Author(s)
  史　天宇、畑中彩里、水瀬雅己、和久　剛、小林　聡
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] A transcription factor NRF1(NFE2L1) activates selective autophagy by inducing p62 and GABARAPL1 expression upon proteasome inhibition.2022
- Author(s)
  Atsushi Hatanaka, Sota Nakada, Iori Aketa, Katsuya Satoh, Gen Matsumoto, Akira Watanabe, Tomofumi Yoshida, Shigeo Takamori, Tsuyoshi Waku, Akira Kobayashi
- Organizer
  The 10th International Symposium on Autophagy (ISA2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF3はアルギニンによるmTORC1活性化を介して腫瘍を増大させる2022
- Author(s)
  廣瀬修平、和久　剛、増田　遥、明田伊鳳、畠中敦至、大澤　毅、曽我朋義、小林　聡
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] 転写因子Nrf3は細胞膜輸送系の制御を介してメラニン産生カスケードを最適化する2022
- Author(s)
  和田恵佳、中田創太、増田　遥、住春　菜、和久剛、小林　聡
- Organizer
  第68回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF3はアルギニンによるmTORC1活性化を介して腫瘍を増大させる2022
- Author(s)
  廣瀬修平、和久　剛、増田　遥、明田伊鳳、畠中敦至、大澤　毅、曽我朋義、小林　聡
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] 転写因子NRF3によるミトコンドリア動態制御の可能性2022
- Author(s)
  明田伊鳳、廣瀬修平、増田　遥、和田恵佳、佐藤清敏、曽我朋義、和久　剛、小林　聡
- Organizer
  第68回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] NRF3-CCN2経路による膵臓の新たな悪性化機構2022
- Author(s)
  小林　聡
- Organizer
  第13回日本CCNファミリー研究会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] 転写因子Nrf3は細胞膜輸送系の制御を介してメラニン産生カスケードを最適化する2022
- Author(s)
  和田恵佳、中田創太、増田　遥、住　春菜、廣瀬修平、明田伊鳳、和久　剛、小林　聡
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] がん微小環境におけるオーファン転写因子NRF3のアルギニンを介した新たな腫瘍増大機構2022
- Author(s)
  小林　聡
- Organizer
  佐賀大学農学部生化学セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] A transcription factor NRF1(NFE2L1) activates selective autophagy by inducing p62 and GABARAPL1 expression upon proteasome inhibition.2022
- Author(s)
  Atsushi Hatanaka, Sota Nakada, Iori Aketa, Katsuya Satoh, Gen Matsumoto, Akira Watanabe, Tomofumi Yoshida, Shigeo Takamori, Tsuyoshi Waku, Akira Kobayashi
- Organizer
  The 10th International Symposium on Autophagy (ISA2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] プロテオスタシスないしアルギニン欠乏シグナルに対する新たな生体応答2022
- Author(s)
  小林　聡
- Organizer
  第16回日本臨床ストレス応答学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04659
[Presentation] がん微小環境におけるオーファン転写因子NRF3のアルギニンを介した新たな腫瘍増大機構2022
- Author(s)
  小林　聡
- Organizer
  佐賀大学農学部生化学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] 転写因子NRF3によるミトコンドリア動態制御の可能性2022
- Author(s)
  明田伊鳳、廣瀬修平、増田　遥、和田恵佳、佐藤清敏、曽我朋義、和久　剛、小林　聡
- Organizer
  第68回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] Identification of Pathological Function of the NRF3-CTGF Axis in Pancreatic Cancer Malignancies.2022
- Author(s)
  Takuto Michihara, 〇Katsuya Satoh, Kohei Yamamoto, Yue Gao, Tsuyoshi Waku, Akira Kobayashi
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] NRF3-CTGF経路による膵臓がん悪性化機構の解明2021
- Author(s)
  道原琢登、和久剛、小林聡
- Organizer
  第44回日本分子生物学会年会、横浜
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF3-CTGF経路による膵臓がん悪性化機構の解明2021
- Author(s)
  道原琢登、和久剛、小林聡
- Organizer
  第44回日本分子生物学会年会、横浜
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] NRF3はアミノ酸取り込みおよび葉酸代謝を介したmTORC1活性化によって腫瘍増大に寄与する2021
- Author(s)
  廣瀬修平、増田遥、曽我朋義、和久剛、小林聡
- Organizer
  第80回日本癌学会学術年会、横浜
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] NRF3-TAZ経路による膵がん浸潤・転移機構の解析2021
- Author(s)
  浅野太我、道原琢登、和久剛、小林聡
- Organizer
  第67回日本生化学会近畿支部例会　オンライン開催
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] NRF3はアミノ酸取り込みおよび葉酸代謝を介したmTORC1活性化によって腫瘍増大に寄与する2021
- Author(s)
  廣瀬修平、増田遥、曽我朋義、和久剛、小林聡
- Organizer
  第80回日本癌学会学術年会、横浜
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] 転写因子NRF3によるアミノ酸独占を介したがん免疫回避仮説の検証2021
- Author(s)
  増田遥、廣瀬修平、和久剛、小林聡
- Organizer
  第44回日本分子生物学会年会、横浜
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] NRF1 and NRF3 complementarily maintain basal proteasome activity in cancer cells through CPEB3-Mediated translational repression.2021
- Author(s)
  Tsuyoshi Waku, Akira Kobayashi
- Organizer
  第44回日本分子生物学会年会、シンポジウム（招待講演）横浜
- Invited
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] NRF1 and NRF3 complementarily maintain basal proteasome activity in cancer cells through CPEB3-Mediated translational repression.2021
- Author(s)
  Tsuyoshi Waku, Akira Kobayashi
- Organizer
  第44回日本分子生物学会年会、シンポジウム（招待講演）横浜
- Invited
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF3-TAZ経路による膵がん浸潤・転移機構の解明2021
- Author(s)
  浅野太我、道原琢登、和久剛、小林聡
- Organizer
  第44回日本分子生物学会年会、横浜
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] NRF3はアミノ酸取り込みを介したmTORC1活性化によって腫瘍増大に寄与する2021
- Author(s)
  廣瀬修平、増田遥、和久剛、小林聡
- Organizer
  第44回日本分子生物学会年会、横浜
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF1 and NRF3 complementarily maintain basal proteasome activity in cancer cells through CPEB3-Mediated translational repression2021
- Author(s)
  和久剛, 小林聡
- Organizer
  第44回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07650
[Presentation] NRF1はプロテアソーム阻害時にp62を介した選択的オートファジーを誘導する2021
- Author(s)
  中田創太、畠中惇至、松本弦、和久剛、貫名信行、小林聡
- Organizer
  第44回日本分子生物学会年会、横浜
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] 転写因子NRF3によるアミノ酸独占を介したがん免疫回避仮説の検証2021
- Author(s)
  増田遥、廣瀬修平、和久剛、小林聡
- Organizer
  第44回日本分子生物学会年会、横浜
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF3-TAZ経路による膵がん浸潤・転移機構の解明2021
- Author(s)
  浅野太我、道原琢登、和久剛、小林聡
- Organizer
  第44回日本分子生物学会年会、横浜
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF3はアミノ酸取り込みを介したmTORC1活性化によって腫瘍増大に寄与する2021
- Author(s)
  廣瀬修平、増田遥、和久剛、小林聡
- Organizer
  第44回日本分子生物学会年会、横浜
- Data Source
  KAKENHI-PROJECT-21K19743
[Presentation] NRF3-TAZ経路による膵がん浸潤・転移機構の解析2021
- Author(s)
  浅野太我、道原琢登、和久剛、小林聡
- Organizer
  第67回日本生化学会近畿支部例会　オンライン開催
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF1はプロテアソーム阻害時にp62を介した選択的オートファジーを誘導する2021
- Author(s)
  中田創太、畠中惇至、松本弦、和久剛、貫名信行、小林聡
- Organizer
  第15回日本臨床ストレス学会
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF3-CTGF経路による膵がん悪性化機構の解明2020
- Author(s)
  道原琢登、和久剛、小林聡
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF3-CTGF経路による膵がん悪性化機構の解明2020
- Author(s)
  道原琢登、和久剛、小林聡
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] NRF3によるSREBP2活性とLDL取込みを介したコレステロール代謝制御メカニズムの解明2020
- Author(s)
  渥美友里、萩原透、田村奈都子、浦野泰臣、和久剛、小林聡
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H04135
[Presentation] NRF3によるSREBP2活性とLDL取込みを介したコレステロール代謝制御メカニズムの解明2020
- Author(s)
  渥美友里、萩原透、田村奈都子、浦野泰臣、和久剛、小林聡
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] 転写因子NRF3はがん細胞内のセリン代謝を制御する2020
- Author(s)
  和久剛、廣瀬修平1、谷美里、佐藤清敏、大澤毅、曽我朋義、小林聡
- Organizer
  先端モデル動物プラットフォーム若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-19K07650
[Presentation] NRF1とNRF3は翻訳制御を介してがん細胞の構成的プロテアソーム活性を相補的に維持する2019
- Author(s)
  平岡　都、片山寛之、和久　剛、小林　聡
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] ApcΔ716マウスを用いたNrf3による腫瘍増大機構の解析2019
- Author(s)
  高越、武藤誠、和久剛、小林聡
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] NRF3-POMP 経路を介したユビキチン非依存的なタンパク質分解の誘導によるがん増悪メカニズム2019
- Author(s)
  和久剛、濱崎純、浜窪隆雄、渡辺亮、村田茂穂、小林聡
- Organizer
  第5回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] Genome-wide transcriptome analyses for NRF1 and NRF3 upon proteasome inhibition2019
- Author(s)
  Atsushi Hatanaka, Natsuko Tamura, Tsuyoshi Waku, Akira Watanabe, Akira Kobayashi
- Organizer
  The Environmental Response V
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] The NRF3-POMP axis promotes tumorigenesis through activating ubiquitin-independent protein degradation by 20S proteasome2019
- Author(s)
  Tsuyoshi Waku, Takao Hamakubo, Akira Watanabe, Shigeo Murata, Akira Kobayashi
- Organizer
  Cold Spring Harbor meeting: Mechanisms of Metabolic Signaling
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] 膵ガンにおける転写因子NRF3（NFE2L3）のVEGF-Aを介した血管新生の可能性2019
- Author(s)
  畑中彩里、青野栞、道原琢登、和久剛、小林聡
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] がん細胞における転写因子NRF3 とNRF1による相補的な構成的プロテアソーム活性制御機構2019
- Author(s)
  小林　聡、和久　剛
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] NRF1 and NRF3 complementarily maintain a basal proteasome activity via CPEB3-mediated translational repression in cancer2019
- Author(s)
  Hiroyuki Katayama, Tsuyoshi Waku, Miyako Hiraoka, Atsushi Hatanaka, Akira Kobayashi
- Organizer
  The Environmental Response V
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] NRF1とNRF3は翻訳制御を介してがん細胞の構成的プロテアソーム活性を相補的に維持する2019
- Author(s)
  平岡　都、片山寛之、和久　剛、小林　聡
- Organizer
  第14回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] NRF3(NFE2L3) contributes to colorectal cancer development through 20S proteasome assembly and the ubiquitin-independent proteolysis.2019
- Author(s)
  Tsuyoshi Waku, Jun Hamazaki, Takao Hamakubo, Akira Watanabe, Shigeo Murata, Akira Kobayashi
- Organizer
  The Environmental Response V
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] A CNC family transcription factor NRF3 (NFE2L3) induces cholesterol metabolic genes through SREBP2 activation2019
- Author(s)
  Natsuko Tamura, Toru Hagiwara, Yuri Atsumi, Tsuyoshi Waku, Akira Kobayashi
- Organizer
  The Environmental Response V
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] 転写因子NRF3によるSREBP2発現を介したコレステロール代謝リプログラミングの可能性2019
- Author(s)
  萩原　透、田村奈都子、渥美友里、和久　剛、浦野泰臣、小林　聡
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] A tumorigenic transcription factor NRF3 activates mTORC1 through amino acid uptake2019
- Author(s)
  Shuuhei Hirose, Misato Tani, Tsuyoshi Waku, Akira Kobayashi
- Organizer
  The Environmental Response V
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] MALAT1 lncRNA expression is regulated by NRF3 and induces proliferation in cancer cells.2019
- Author(s)
  Svetlana Ivanoff, Atsushi Hatanaka, Tsuyoshi Waku, Akira Kobayashi
- Organizer
  The Environmental Response V
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] Colorectal cancer addicts ubiquitin-independent 20S proteasomes assembled by the NRF3-POMP axis2019
- Author(s)
  Tsuyoshi Waku, Atsushi Hatanaka, Jun Hamazaki, Takao Hamakubo, Akira Watanabe, Shigeo Murata, Akira Kobayashi
- Organizer
  Cold Spring Harbor meeting: Ubiquitins, Autophagy & Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] がん増悪性転写因子 NRF3 によるアミノ酸取り込みを介した mTORC1 シグナル活性化メカニズム2019
- Author(s)
  廣瀬修平、谷美里、和久剛、小林聡
- Organizer
  第5回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] β-catenin/TCF4 Complex-Mediated Induction of The NRF3 (NFE2L3) Gene in Cancer Cells2019
- Author(s)
  Shiori Aono, Ayari Hatanaka, Atsushi Hatanaka, Yue Gao, Tsuyoshi Waku, Akira Kobayashi
- Organizer
  The Environmental Response V
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] 転写因子NRF3(NFE2L3)はアミノ酸取り込みを介してmTORシグナルを活性化する2019
- Author(s)
  廣瀬修平、谷美里、畠中惇至、萩原透、田村奈都子、和久剛、小林聡
- Organizer
  第66回日本生化学会近畿支部会例会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] 転写因子NRF3(NFE2L3)はアミノ酸取り込みを介してmTORC1シグナルを活性化する2019
- Author(s)
  谷　美里、廣瀬修平、北野妃菜、和久　剛、小林　聡
- Organizer
  第14回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] Breakthroughs in NRF2-related factor NRF3 research: its crucial function in cancer and proteostasis2019
- Author(s)
  Akira Kobayashi
- Organizer
  The Environmental Response V
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] NRF3によるSREBP2発現を介したコレステロール代謝リプログラミングの可能性2019
- Author(s)
  萩原　透、田村奈都子、渥美友里、和久　剛、浦野泰臣、小林　聡
- Organizer
  第14回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] がん細胞におけるβ-catenin/TCF4複合体によるNRF#(NFE2L3)遺伝子の誘導2019
- Author(s)
  畑中彩里、青野栞、畠中惇至、高越、和久剛、小林聡
- Organizer
  第14回日本臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-19K22826
[Presentation] プロテオスタシスの破綻による新たな腫瘍増大メカニズム2018
- Author(s)
  和久剛, 小林聡
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] プロテアソーム制御因子の翻訳制御を介したタンパク質分解調節メカニズムの解明2018
- Author(s)
  片山寛之, 和久剛, 小林聡
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] ストレス応答性転写因子NRF3の20Sプロテアソーム活性化による新たな発ガン機構2018
- Author(s)
  小林聡、和久剛
- Organizer
  第13回臨床ストレス応答学会大会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 腫瘍増大に寄与するプロテオスタシス制御機構2018
- Author(s)
  和久剛、小林聡
- Organizer
  第６回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF3（NFE2L3）によるがん細胞の脂質代謝制御の可能性2018
- Author(s)
  田村奈都子、萩原透、和久剛、小林聡
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 大腸がんの細胞増殖を制御するβ-catenin-NRF3-20Sプロテアソーム経路2018
- Author(s)
  小林聡、青野栞、Chowdhury AM Masudul、畠中惇至、筆宝義隆、和久剛
- Organizer
  第６回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF1とNRF3の翻訳制御を介した新たなプロテアソーム活性調節メカニズムの解明2018
- Author(s)
  片山寛之、平岡都、和久剛、小林聡
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF3（NFE2L3）は20Sプロテアソームアッセンブリを亢進して腫瘍増大に寄与する2018
- Author(s)
  和久剛、村田茂穂、小林聡
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] がんにおける転写因子NRF3(NFE2L3)による新たなプロテアソーム活性化機構2018
- Author(s)
  小林聡
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] トランスクリプトーム解析による転写因子NRF1のがん細胞における機能解明2018
- Author(s)
  畠中惇至、和久剛、渡辺亮、小林聡
- Organizer
  第６回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 大腸ガン細胞におけるNRF3遺伝子の発現誘導メカニズムの解明2018
- Author(s)
  青野栞, 和久剛, 筆宝義隆, 小林聡
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NFE2L3 (NRF3) はin vitroにおいてがん細胞の浸潤と遊走を促進する2018
- Author(s)
  廣瀬修平、谷美里、和久剛、小林聡
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] HIV-1プロテアーゼ阻害剤による転写因子NRF3を標的とした新たな抗がん作用機構2017
- Author(s)
  畠中惇至、行武拓哉、糀美早紀、和久　剛、小林　聡
- Organizer
  第22回日本病態プロテアーゼ学会学術集会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF3はプロテアソーム発現亢進を介してp53依存的なガン抑制シグナルを阻害する2017
- Author(s)
  和久　剛、小林　聡
- Organizer
  転写研究会・新学術領域「転写サイクル」共催　冬の若手ワークショップ2017
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF3（NFE2L3）を過剰発現するヒト肺がん細胞H1299を用いたマウス移植解析2017
- Author(s)
  糀美早紀、和久剛、小林聡
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF3は20プロテアソーム活性亢進を介してガン細胞の増殖を亢進する2017
- Author(s)
  鎌田七海、糀美早紀、和久　剛、小林　聡
- Organizer
  第64回日本生化学会近畿支部会
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] プロテアソームの誘導的発現と疾患2017
- Author(s)
  小林　聡
- Organizer
  ConBio2017 ワークショップ「プロテオスタシス制御の新展開と疾患」
- Invited
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF3（NFE2L3）は20Sプロテアソームの活性亢進を介して腫瘍増大に寄与する2017
- Author(s)
  和久剛、糀美早紀、鎌田七海、辰巳千夏、畠中惇至、小林聡
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF3（NFE2L3）はTGF-β/SMADシグナルを制御する2017
- Author(s)
  廣瀬修平、和久剛、小林　聡
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 構成的プロテアソーム活性の転写因子NRF1とNRF3による協調的制御の可能性2017
- Author(s)
  片山寛之、鎌田七海、和久剛、小林聡
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 白血病で高頻度に変異の起こるTET2のCRドメインはヒストン修飾を認識する2016
- Author(s)
  山形一行、木村宏、小林聡、Yang Shi.
- Organizer
  第4回がんと代謝研究会
- Place of Presentation
  鹿児島県民交流センター（鹿児島県・鹿児島市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 白血病で高頻度に変異の起こるTET2のCRドメインはヒストン修飾を認識する2016
- Author(s)
  山形一行、木村宏、小林聡、Yang Shi.
- Organizer
  平成28年度新学術領域研究「学術研究支援基盤形成【先端モデル動物支援プラットフォーム】若手支援技術講習会
- Place of Presentation
  蓼科グランドホテル滝の湯 (長野県・茅野市）
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] The HRD1-NRF3 axis regulates the proliferation of colon cancer cells by inducing the UHMK1 gene expression.2016
- Author(s)
  AM Masudul Azad Chowdhury, Hiroki Kato, Tsuyoshi Waku, Akira Kobayashi
- Organizer
  Targeting Cancer: 81st Cold Spring Harbor Symposium.
- Place of Presentation
  Cold Spring harbor (USA)
- Year and Date
  2016-06-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF1の活性化メカニズムにおけるシグナルペプチダーゼSEC11Aの機能解析2016
- Author(s)
  畠中惇至、和久剛、谷口浩章、小林聡
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF3によるガン細胞におけるプロテアソーム発現機構2016
- Author(s)
  田中裕也、○鎌田七海、和久剛、小林聡
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] エピジェネティック制御因子HCF-1を介した転写因子NRF1のプロテアソーム発現機構の解析2016
- Author(s)
  松本麻莉子、山形一行、北川大祐、谷口浩章、土谷佳樹、小林聡
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜みなとみらい21（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF1のOGT-HCF-1複合体を介した分解制御機構2016
- Author(s)
  関根弘樹, 加藤幸一郎, 福田愛菜, 鈴木教郎, 岡崎慶斗, Md. Morshedul Alam, 辻田忠志, 小林聡, 山本雅之, 本橋ほづみ
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF3はp53依存的なガン細胞の増殖抑制を阻害する2016
- Author(s)
  和久剛、加藤裕紀、渡辺秀教、岩成宏子、辰巳千夏、畠中惇至、浜窪隆雄、小林聡
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] 転写因子NRF3はガン細胞の20Sプロテアソーム発現を制御する2016
- Author(s)
  鎌田七海、畠中惇至、糀美早紀、和久剛、小林聡
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜みなとみらい21（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] Cysteine rich domain of TET2 protein as a reader of histone H3 K36 mono and di methylation.2016
- Author(s)
  Kazuyuki Yamagata, Hiroshi Kimura, Akira Kobayashi and Yang Shi.
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16H03265
[Presentation] Functional analyses of the transcription factor Nrf1 isoforms by using CRISPR/Cas9 system.2015
- Author(s)
  Kubo, K., Waku, T., Kobayashi, A.
- Organizer
  The Conference on Transposition and Genome Engineering 2015
- Place of Presentation
  奈良
- Year and Date
  2015-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26116725
[Presentation] 転写因子NRF3は細胞周期を調節することで大腸ガン細胞の増殖に関与する.2015
- Author(s)
  加藤裕紀、和久剛、辰巳千夏、小林聡
- Organizer
  新学術領域「転写代謝システム」領域班会議
- Place of Presentation
  熊本
- Year and Date
  2015-06-14
- Data Source
  KAKENHI-PUBLICLY-26116725
[Presentation] CNCファミリー転写因子による転写代謝システムの解析2015
- Author(s)
  小林聡、M Rezaul Karim、谷口浩章
- Organizer
  新学術領域「転写代謝システム」領域班会議
- Place of Presentation
  熊本
- Year and Date
  2015-06-14
- Data Source
  KAKENHI-PUBLICLY-26116725
[Presentation] 転写因子Nrf1による代謝制御2015
- Author(s)
  小林聡
- Organizer
  BMB2015
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-26116725
[Presentation] CK2 regulates the transcriptional activity of Nrf1 to maintain cellular homeostasis2011
- Author(s)
  伊藤義起, 土谷佳樹, 家村俊一郎, 夏目徹, 小林聡
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590277
[Presentation] Dual regulation of the transcriptional activity of Nrf1 by β-TrCP-and Hrd1-dependent degradation mechanisms2011
- Author(s)
  土谷佳樹, 森田智子, 金美姫, 家村俊一郎, 夏目徹, 山本雅之, 小林聡
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22590277
[Presentation] Dual regulation of the transcription factor Nrf1(Nfe2l1) by β-TrCP-and Hrd1-dependent degradation mechanisms2011
- Author(s)
  Tsuchiya, Y., Morita, T., Kim, M., Iemura, S., Natsume, T., Yamamoto, M., and Kobayashi, A.
- Organizer
  EMBO Workshop on Intracellular Proteolysis and Cancer
- Place of Presentation
  Valencia, Spain
- Data Source
  KAKENHI-PROJECT-22590277
[Presentation] Central nervous system-specific deletion of transcription factor Nrf1causes progressive motor neuronal dysfunction2010
- Author(s)
  Tsukide, T., Kobayashi, A., Miyasaka, T. Morita, T., Mizoroki, T., Saito, Y., Ihara, Y. Takashima, A., Noguchi, N. Fukamizu, A., Hirotsu, Y., Ohtsuji, M., Katsuoka, F. and Yamamoto M
- Organizer
  5th International Symposium on GATA transcription factor
- Place of Presentation
  Sendai, Japan
- Data Source
  KAKENHI-PROJECT-22590277
[Presentation] リン酸化による転写因子Nrf1の機能制御機構解析2010
- Author(s)
  伊藤義起, 土谷佳樹, 家村俊一郎, 夏目徹, 小林聡
- Organizer
  分子生物学会第10回春季シンポジウム
- Place of Presentation
  松島,宮城
- Data Source
  KAKENHI-PROJECT-22590277
[Presentation] Cytoplasmic and nuclear degradation mechanisms regulate biological function of the transcription factor Nrf12010
- Author(s)
  Morita, T., Tsuchiya, Y., Kim, M., Iemura, S., Tsukide, T., Natsume, T., Yamamoto, M., and Kobayashi, A.
- Organizer
  第33回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590277
[Presentation] CK2 regulates the transcription factor Nrf1 to maintain cellular homeostasis2010
- Author(s)
  Ito, Y., Tsuchiya, Y., Iemura, S., Natsume, T., and Kobayashi, A.
- Organizer
  6th International Conference on Protein Kinase CK2
- Place of Presentation
  Cologne, Germany
- Data Source
  KAKENHI-PROJECT-22590277
[Presentation] 老化をもたらす酸化ストレスに対する生体防御機構2008
- Author(s)
  小林聡
- Organizer
  BMB2008
- Place of Presentation
  神戸ポートピア
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19044006
[Presentation] 老化をもたらす酸化ストレスに対する生体防御機構2008
- Author(s)
  小林聡
- Organizer
  BMB2008
- Place of Presentation
  神戸ポートピア
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590268
[Presentation] 老化をもたらす酸化ストレスに対する生体防御機構2008
- Author(s)
  小林聡
- Organizer
  BMB2008
- Place of Presentation
  神戸ポートピア
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19045005
[Presentation] 老化をもたらす酸化ストレスに対する生体防御機構2008
- Author(s)
  小林聡
- Place of Presentation
  神戸
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-19590268
[Presentation] Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based Ub E3 ligase to regulate proteasomal degradation of Nrf2.2007
- Author(s)
  小林聡
- Organizer
  JST-ERATO Yamamoto Environmental Response Project International Symposium
- Place of Presentation
  つくばエポカル
- Data Source
  KAKENHI-PROJECT-19045005
[Presentation] Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based Ub E3 ligase to regulate proteasomal degradation of Nrf22007
- Author(s)
  小林聡
- Organizer
  JST-ERATO Yamamoto Environmental Response Project International Symposium
- Place of Presentation
  つくばエポカル
- Data Source
  KAKENHI-PROJECT-19044006
[Presentation] Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based Ub E3 liqase to requlate proteasomal deqradation of Nrf2.2007
- Author(s)
  小林聡
- Organizer
  JST-ERATO Yamamoto Environmental Response Project International Symposium
- Place of Presentation
  つくばエポカル
- Data Source
  KAKENHI-PROJECT-19590268
[Presentation] USP15 stabilizes and activates the transcription factor Nrf1 by deubiquitination.
- Author(s)
  Fukagai, K., Taniguchi, H., Natsume, T., Tsuruta, F., Chiba, T., Kobayashi, A.
- Organizer
  ZOMESVIII
- Place of Presentation
  Xiamen, China
- Year and Date
  2014-11-18 – 2014-11-21
- Data Source
  KAKENHI-PUBLICLY-26116725
[Presentation] 神経特異的Nrf1KOマウスの神経変性に対する還元型グルタチオン経口投与の効果
- Author(s)
  久保花織、谷口浩章、森田匡彦、小林聡
- Organizer
  冬の若手ワークショップ2015＠伊香保
- Place of Presentation
  伊香保
- Year and Date
  2015-02-05 – 2015-02-07
- Data Source
  KAKENHI-PUBLICLY-26116725
[Presentation] Neural stemcell-specific disruption of the transcription factor Nrf1 (NFE2L1) gene leads to aberrant accumulation of phosphorylated α-synuclein in cerebellar Purkinje cells.
- Author(s)
  Taniguchi, H., Okamuro, S., Miyasaka, T., Kanazawa, Y., Matsumoto, M., Kubo, K., Katahira, T., Motoyama, J., Kobayashi, A.
- Organizer
  第37回日本分子生物学会年会.
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-26116725
[Presentation] Homeostatic maintenance of neuronal activity by the transcription factor Nrf1 (NFE2L1).
- Author(s)
  Okamuro, S., Taniguchi, H., Kanazawa, Y., Katahira, T., Motoyama, J., Yamamoto, M., Kobayashi, A.
- Organizer
  第37回日本神経科学会
- Place of Presentation
  横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PUBLICLY-26116725

1. Waku Tsuyoshi (40613584)

# of Collaborated Projects: 7 results

# of Collaborated Products: 98 results
2. IGARASHI Kazuhiko (00250738)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
3. TSUCHIYA Yoshiki (30456777)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
4. HAYASHI Norio (00004606)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
5. YAMAMOTO Masayuki (50166823)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. 古山和道 (80280874)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. TAKETANI Shigeru (20121949)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. FUJII Yoshiaki (00098146)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SOGAWA Kazuhiro (80175421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 峯岸直子 (40271895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 菊池康夫 (10004467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 依馬正次 (60359578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. URANO Yasuomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. Hamakubo Takao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. SHIMA Hiroki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. KATSUOKA Fumiki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 山形一行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 濱崎純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 武谷茂

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 佐藤克也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 深水昭吉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kobayashi Akira 小林 聡

KOBAYASHI AKIRA 小林 聡

KOBAYASHI Akira 小林 聡

Research Projects

Research Products

Co-Researchers

Elucidation of the mechanism of growth of refractory pancreatic cancer and development of new therapeutic strategies.Principal Investigator

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Physiological function of arginine signaling:macropinocytosisand tumor immune evasionPrincipal Investigator

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腫瘍免疫系における転写因子NRF3を介した肥満パラドックスの分子メカニズム解明

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Investigation of molecular mechanisms underlying selective autophagy activation upon proteasome dysfunctionPrincipal Investigator

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Improvement of immune checkpoint inhibition therapy for the treatment of pancreatic cancerPrincipal Investigator

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Elucidation of novel physiological effects of amino acid signaling and its mediated lifespan extension and immune exhaustPrincipal Investigator

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Pathophysiological role of NRF3-mediated protein degradation in colorectal cancer development

Principal Investigator

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Examination of coupled gene expression mechanisms of proteasome for anti-agingPrincipal Investigator

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Molecular analysis of the proteasome gene expression and its application to anti-aging.Principal Investigator

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脂肪滴を介した新たな転写代謝システムの解明Principal Investigator

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Advanced investigation of molecular regulation of lipid metabolism by the transcription factor Nrf1Principal Investigator

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タンパク質分解制御による酸化ストレス応答機構の解明Principal Investigator

Principal Investigator

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Research Institution

酸化ストレスセンサーKeap1のストレス応答機構Principal Investigator

Principal Investigator

Kobayashi Akira 小林聡

KOBAYASHI AKIRA 小林聡

KOBAYASHI Akira 小林聡