Kinoshita Kazuo 木下和生

… Alternative Names

Researcher Number	50293874
Other IDs
External Links
Affiliation (Current)	2022: 静岡社会健康医学大学院大学, 社会健康医学研究科, 教授 2022: 地方独立行政法人静岡県立病院機構静岡県立総合病院(救急診療部、循環器病診療部、がん診療部、臨床診療部, リサーチサポートセンター, 主席研究員
Affiliation (based on the past Project Information) *help	2022: 静岡社会健康医学大学院大学, 社会健康医学研究科, 教授 2016: 滋賀県立成人病センター(研究所), 遺伝子研究部門, 専門研究員 2015: 滋賀県立成人病センター(研究所), その他部局等, 専門研究員 2005 – 2014: 滋賀県立成人病センター(研究所), 遺伝子研究部門, 専門研究員 2009: Research Institute, Shiga Medical Center, 遺伝子研究部門, 專門研究員 … More
Review Section/Research Field	Principal Investigator Biological Sciences / Experimental pathology / Immunology / General medical chemistry / Evolutionary biology / Pathological medical chemistry Except Principal Investigator Thoracic surgery / Immunology / Biological Sciences / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator AID / 体細胞突然変異 / クラススイッチ / 突然変異 / DNA組換え / 抗体 / 人工基質 / RNA編集 / 免疫学 / ゲノム … More Except Principal Investigator Stat / 呼吸器外科学 / 肺癌 / 肺腺がん / 上皮成長因子受容体 / AID / サイトカインレセプター / γδT細胞 / シグナル伝達 / DNA組換え / ヒストンアセチル化 / 転写共役因子 / レトロウイルス / STAT / レトロウィルス / cytokine receptor / γδT cell / signal transduction / DNA recombination / histone acetylation / transcriptional coactivator / retrovirus / アレルギー・喘息 / 遺伝子 / 感染症 / 発現制御 / 免疫学 / 免疫記憶細胞 / 転写因子 / 胚工学 / BCL6 / AP-1 / STAT3 / c-Fos / Blimp-1 / 胚中心B細胞 / IL-21 / Follicular helper T cell / 体細胞突然変異 / ADAR1 / クラススイッチ / 遺伝子欠損マウス / メモリーT細胞 / メモリーB細胞 / 癌 / ゲノム / Allergy / CO Gene / Infectious Disease / Transcription / Immunology / Immune Memory Cell / Transcription Factor / Transgenic Technology / 炎症性腸疾患 / リン脂質 / 腸閉鎖 / 小児 Less

TTC7A欠損に起因する難治性腸閉鎖症のパラログ遺伝子発現促進による治療
- Principal Investigator
  
  金井理紗
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Shizuoka Prefectural Hospital Organization
Elucidation of erythroid differentiation using fsn micePrincipal Investigator
- Principal Investigator
  
  Kinoshita Kazuo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  Research Institute, Shiga Medical Center
Carcinogenesis by a mutagenic enzyme AIDPrincipal Investigator
- Principal Investigator
  
  KAZUO Kinoshita
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Research Institute, Shiga Medical Center
Mechanisms of diseases by chromosomal translocationPrincipal Investigator
- Principal Investigator
  
  KINOSHITA Kazuo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Research Institute, Shiga Medical Center
Is activation-induced cytidine deaminase related to oncogenesis of lung cancer with induction of gene mutations observed in lung cancer?
- Principal Investigator
  
  SONOBE Makoto
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Kyoto University
Interaction between endogeneous mutator AID and exogenous oncogenic factors in carcinogenesisPrincipal Investigator
- Principal Investigator
  
  KINOSHITA Kazuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Research Institute, Shiga Medical Center
Carcinogenesis by a genome mutator AIDPrincipal Investigator
- Principal Investigator
  
  KINOSHITA Kazuo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Research Institute, Shiga Medical Center
発がんにおける内在的突然変異誘導因子と外的因子の相互作用解析モデルの構築Principal Investigator
- Principal Investigator
  
  木下和生
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Interaction between endogenous mutator AID and exogenous oncogenic factors in carcinogenesisPrincipal Investigator
- Principal Investigator
  
  KINOSHITA Kazuo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyoto University
精子形成における突然変異誘導機構の探索Principal Investigator
- Principal Investigator
  
  木下和生
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Evolutionary biology
- Research Institution
  Kyoto University
Study for Development and Maintenance of mune Memory
- Principal Investigator
  
  TOKUHISA Takeshi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
RNA編集による抗体遺伝子のDNA情報変換機構Principal Investigator
- Principal Investigator
  
  木下和生
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
RNA編集による抗体遺伝子のDNA情報変換機構Principal Investigator
- Principal Investigator
  
  木下和生
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyoto University
免疫グロブリン遺伝子における遺伝情報変換機構の解析Principal Investigator
- Principal Investigator
  
  木下和生
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
腸管粘膜におけるIgA抗体産生機構の解析Principal Investigator
- Principal Investigator
  
  木下和生
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
免疫グロブリンクラススイッチの分子機構解析Principal Investigator
- Principal Investigator
  
  木下和生
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  Kyoto University
Induction mechanism of V-J recombination by signaling molecules of the IL-7 receptor
- Principal Investigator
  
  IKUTA Koichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Immunology
- Research Institution
  KYOTO UNIVERSITY

All 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation Patent

[Journal Article] TGF-β Suppression of HBV RNA through AID-Dependent Recruitment of an RNA Exosome Complex2015
- Author(s)
  Liang, G., Liu, G., Kitamura, K., Wang, Z., Chowdhury, S., Monjurul, A. M., Wakae, K., Koura, M., Shimadu, M., Kinoshita, K., and Muramatsu, M.
- Journal Title
  
  Plos Pathogen
  
  Volume: 11
- DOI
  10.1371/journal.ppat.1004780
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390097, KAKENHI-PROJECT-26460993, KAKENHI-PROJECT-26861318
[Journal Article] Chronic lung injury by constitutive expression of activation-induced cytidine deaminase leads to focal mucous cell metaplasia and cancer2015
- Author(s)
  Kitamura, J., Uemura, M., Kurozumi, M., Sonobe, M., Manabe, T., Hiai, H., Date, H., and Kinoshita, K.
- Journal Title
  
  PLoS One
  
  Volume: 10
- DOI
  10.1371/journal.pone.0117986
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390097
[Journal Article] Activation-induced cytidine deaminase is dispensable for virus-mediated liver and skin tumor development in mouse models2014
- Author(s)
  Nguyen, T., Xu, J., Chikuma, S., Hiai, H., Kinoshita, K., Moriya, K., Koike, K., Marcuzzi, G. P., Pfister, H., Honjo, T., Kobayashi, M.
- Journal Title
  
  Int Immunol
  
  Volume: in press Pages: 1-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390097
[Journal Article] 核酸編集酵素 AID の発癌への関与2013
- Author(s)
  喜夛村次郎、木下和生、伊達洋至
- Journal Title
  
  日本臨床
  
  Volume: 71, Suppl 6 Pages: 118-121
- Data Source
  KAKENHI-PROJECT-23390097
[Journal Article] Targeting activation-induced cytidine deaminase prevents colon cancer development despite persistent colonic inflammation2012
- Author(s)
  Takai A, Marusawa H, Minaki Y, WatanabeT, Nakase H, Kinoshita K, Tsujimoto G,Chiba T.
- Journal Title
  
  Oncogene
  
  Volume: 31 Pages: 1733-1742
- DOI
  10.1038/onc.2011.352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229009, KAKENHI-PROJECT-23390097, KAKENHI-PROJECT-23390196, KAKENHI-PROJECT-24229005
[Journal Article] Chromosomal manipulation by site-specific recombinases and fluorescent protein-based vectors.2010
- Author(s)
  Uemura, M, Niwa, Y, Kakazu, N, Adachi, N, Kinoshita, K.
- Journal Title
  
  PLoS ONE vol.5.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590326
[Journal Article] Chromosomal manipulation by site-specific recombinases and fluorescent protein-based vectors.2010
- Author(s)
  Uemura, M, Niwa, Y, Kakazu, N, Adachi, N, Kinoshita, K
- Journal Title
  
  PLoS ONE 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590326
[Journal Article] A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.2009
- Author(s)
  Takai, A, Toyoshima, T, Uemura, M, Kitawaki, Y, Marusawa, H, Hiai, H, Yamada, S, Okazaki, IM, Honjo, T, Chiba, T, Kinoshita, K.
- Journal Title
  
  Oncogene 28
  
  Pages: 469-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] Carboxy-terminal domain of AID required for its mRNA complex formation in vivo.2009
- Author(s)
  Nonaka, T, Doi, T, Toyoshima, T, Muramatsu, M, Honjo, T, Kinoshita, K.
- Journal Title
  
  Proc Natl Acad Sci U S A 106
  
  Pages: 2747-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] Activation-induced cytidine deaminase links between inflammation and the development of colitis-associated colorectal cancers.2008
- Author(s)
  Endo, Y, Marusawa, H, Kou, T, Nakase, H, Fujii, S, Fujimori, T, Kinoshita, K, Honjo, T, Chiba, T.
- Journal Title
  
  Gastroenterology 135
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] Activation-induced cytidine deaminase links bile duct inflammation to human cholangiocarcinoma.2008
- Author(s)
  Komori, J, Marusawa, H, Machimoto, T, Endo, Y, Kinoshita, K, Kou, T, Haga, H, Ikai, I, Uemoto, S, Chiba, T.
- Journal Title
  
  Hepatology 47
  
  Pages: 888-896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] High expression of activation induced cytidine deaminase in human bile duct epithelium during cholangiocarcinogenesis.2007
- Author(s)
  Komori, J, Marusawa, H, Machimoto, T, Endo, Y, Kinoshita, K, Kou, T, Haga, H, Ikai, I, Uemoto, S, Honjo, T, Chiba, T.
- Journal Title
  
  Gastroenterology 132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] Ectopic expression of activation- induced cytidine deaminase in ulcerative colitis-associated colorectal cancers.2007
- Author(s)
  Kou, T, Marusawa, H, Endo, Y, Nakase, H, Fujii, S, Kinoshita, K, Fujimori, T, Honjo, T, Chiba, T.
- Journal Title
  
  Gastroenterology 132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling.2007
- Author(s)
  Endo, Y, Marusawa, H, Kinoshita, K, Morisawa, T, Sakurai, T, Okazaki, IM, Watashi, K, Shimotohno, K, Honjo, T, Chiba, T.
- Journal Title
  
  Oncogene 26
  
  Pages: 5587-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] Helicobacter pylori infection triggers aberrant expression of activation- induced cytidine deaminase in gastric epithelium.2007
- Author(s)
  Matsumoto, Y, Marusawa, H, Kinoshita, K, Endo, Y, Kou, T, Morisawa, T, Azuma, T, Okazaki, IM, Honjo, T, Chiba, T.
- Journal Title
  
  Nat Med 13
  
  Pages: 470-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] Activation-induced cytidine deaminase (AID) promotes B cell lymphomagenesis in Emu-cmyc transgenic mice.2007
- Author(s)
  Kotani, A, Kakazu, N, Tsuruyama, T, Okazaki, IM, Muramatsu, M, Kinoshita, K, Nagaoka, H, Yabe, D, Honjo, T.
- Journal Title
  
  Proc Natl Acad Sci U S A 104
  
  Pages: 1616-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.2006
- Author(s)
  Kou, T, Marusawa, H, Kinoshita, K, Endo, Y, Okazaki, IM, Ueda, Y, Kodama, Y, Haga, H, Ikai, I, Chiba, T.
- Journal Title
  
  Int J Cancer 120
  
  Pages: 469-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] The dark side of activation-induced cytidine deaminase: relationship with leukemia and beyond.2006
- Author(s)
  Kinoshita, K, Nonaka, T.
- Journal Title
  
  Int J Hematol 83
  
  Pages: 201-7
- NAID
  10017421763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] The Dark Side of Activation-Induced Cytidine Deaminase : Relationship with Leukemia and Beyond2006
- Author(s)
  Kinoshita, K. et al.
- Journal Title
  
  Int.J.Hematol. 83・3
  
  Pages: 201-207
- NAID
  10017421763
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390115
[Journal Article] The dark side of activation-induced cytidine deaminase : relationship with leukemia and beyond2006
- Author(s)
  Kinoshita, K. et al.
- Journal Title
  
  Int.J.Hematol 83・3
  
  Pages: 201-207
- NAID
  10017421763
- Data Source
  KAKENHI-PROJECT-18390122
[Journal Article] The dark side of activation-induced cytidine deaminase : relationship with leukemia and beyond2006
- Author(s)
  Kinoshita, K. et al.
- Journal Title
  
  Int. J. Hematol. 83・3
  
  Pages: 201-207
- NAID
  10017421763
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] Negative regulation of activation- induced cytidine deaminase in B cells.2006
- Author(s)
  Muto, T, Okazaki, IM, Yamada, S, Tanaka, Y, Kinoshita, K, Muramatsu, M, Nagaoka, H, Honjo, T.
- Journal Title
  
  Proc Natl Acad Sci U S A 103
  
  Pages: 2752-2757
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013042
[Journal Article] A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression2005
- Author(s)
  Kotani, A., Okazaki, I.M., M., Muramatsu, M., Kinoshita, K., Begum, N.A., Nakajima, T., Saito, H., Honjo, T.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 102
  
  Pages: 4506-4511
- Data Source
  KAKENHI-PROJECT-16390115
[Journal Article] A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression2005
- Author(s)
  Kotani, A., Okazaki, I.M., Muramatsu, M., Kinoshita, K., Begum, N.A., Nakajima, T., Saito, H., Honjo, T.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 102
  
  Pages: 4506-4511
- Data Source
  KAKENHI-PROJECT-16021226
[Journal Article] A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression2005
- Author(s)
  Kotani, A., Okazaki, I.M., Muramatsu, M., Kinoshita, K., Begum, N.A., Nakajima, T., Saito, H., Honjo, T.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 102
  
  Pages: 4506-4511
- Data Source
  KAKENHI-PROJECT-15657056
[Journal Article] De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination2004
- Author(s)
  Begum, N.A., Kinoshita, K., Muramatsu, M., Nagaoka, H., Shinkura, R., Honjo, T.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 101
  
  Pages: 13003-13007
- Data Source
  KAKENHI-PROJECT-15657056
[Journal Article] Separate domains of AID are required for somatic hypermutation and class-switch recombination2004
- Author(s)
  Shinkura, R., Ito, S., Begum, N.A., Nagaoka, H., Muramatsu, M., Kinoshita, K., Sakakibara, Y., Hijikata, H., Honjo, T.
- Journal Title
  
  Nat.Immunol. 5
  
  Pages: 707-712
- Data Source
  KAKENHI-PROJECT-16390115
[Journal Article] Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch2004
- Author(s)
  Begum, N.A., Kinoshita, K., Kakazu, N., Muramatsu, M., Nagaoka, H., Shinkura, R., Biniszkiewicz, D, Boyer, L.A., Iaenisch, R., Honjo, T.
- Journal Title
  
  Science 305
  
  Pages: 1160-1163
- Data Source
  KAKENHI-PROJECT-16021226
[Journal Article] De novo protein synthesis is required for activation-induced cytidine deaminase-dependent DNA cleavage in immunoglobulin class switch recombination2004
- Author(s)
  Begum, N.A., Kinoshita, K., Muramatsu, M., Nagaoka, H., Shinkura, R., Honjo, T.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 101
  
  Pages: 13003-13007
- Data Source
  KAKENHI-PROJECT-16390115
[Journal Article] Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch2004
- Author(s)
  Begum, N.A., Kinoshita, K., Kakazu, N., Muramatsu, M., Nagaoka, H., Shinkura, R., Biniszkiewicz, D., Boyer, L.A., Jaenisch, R., Honjo, T.
- Journal Title
  
  Science 305
  
  Pages: 1160-1163
- Data Source
  KAKENHI-PROJECT-15657056
[Journal Article] Separate domains of AID are required for somatic hypermutation and class-switch recombination2004
- Author(s)
  Shinkura, R., Ito, S., Begum, N.A., Nagaoka, H., Muramatsu, M., Kinoshita, K., Sakakibara, Y., Hijikata, H., Honjo, T.
- Journal Title
  
  Nat.Immunol. 5
  
  Pages: 707-712
- Data Source
  KAKENHI-PROJECT-16021226
[Journal Article] De novo protein synthesis is required for activation-induced cytidine deanmiase-dependent DNA cleavage in immunoglobulin class switch recombination2004
- Author(s)
  Begum, N.A., Kinoshita, K., Muramatsu, M., Nagaoka, H., Shinkura, R., Honjo, T.
- Journal Title
  
  Proc.Natl.Acad.Sci.U.S.A. 101
  
  Pages: 13003-13007
- Data Source
  KAKENHI-PROJECT-16021226
[Journal Article] Uracil DNA glycosylase activity is dispensable for immunoglobulin class switch2004
- Author(s)
  Begum, N.A., Kinoshita, K., Kakazu, N., Muramatsu, M., Nagaoka, H., Shinkura, R., Biniszkiewicz, D., Boyer, L.A., Jaenisch, R., Honjo, T.
- Journal Title
  
  Science 305
  
  Pages: 1160-1163
- Data Source
  KAKENHI-PROJECT-16390115
[Journal Article] Separate domains of AID are required for somatic hypermutation and class-switch recombination2004
- Author(s)
  Shinkura, R., Ito, S., Begum, N.A., Nagaoka, H., Muramatsu, M., Kinoshita, K., Sakakibara, Y., Hijikata, H., Honjo, T.
- Journal Title
  
  Nat.Immunol. 5
  
  Pages: 707-712
- Data Source
  KAKENHI-PROJECT-15657056
[Patent] レーザーマイクロダイセクション法およびその利用、並びに、油性封入剤2011
- Inventor(s)
  木下　和生
- Industrial Property Rights Holder
  木下　和生
- Industrial Property Rights Type
  特許
- Patent Publication Number
  2012-205572
- Filing Date
  2011-04-01
- Acquisition Date
  2014-02-07
- Data Source
  KAKENHI-PROJECT-23390097
[Presentation] EXPRESSION OF P63 IN ALVEOLAR LESION OF TRANSGENIC MICE EXPRESSING A MUTAGENIC CYTIDINE DEAMINASE, AID2013
- Author(s)
  iro Kitamura, Munehiro Uemura, Hiroshi Hiai and Kazuo Kinoshita
- Organizer
  6th p63/p73 International Workshop
- Place of Presentation
  木更津
- Data Source
  KAKENHI-PROJECT-23390097
[Presentation] AID は紫外線非依存的に皮膚扁平上皮癌の発生を促進する2013
- Author(s)
  野中太一郎, 植村宗弘, 日合弘, 木下和生
- Organizer
  第７２回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23390097
[Presentation] 部位特異的組換え酵素と蛍光タンパクを用いた染色体手術法の開発2010
- Author(s)
  植村宗弘, 丹羽陽子, 木下和生
- Organizer
  第57回日本生化学会近畿支部例会
- Place of Presentation
  奈良先端科学技術大学院大学
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-20590326
[Presentation] Cre組換え酵素による染色体間組換え頻度測定により明らかとなったテロメア近傍遺伝子のアクセシビリティー2010
- Author(s)
  植村宗弘, 丹羽陽子, 嘉数直樹、足立典隆、木下和生
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20590326
[Presentation] Cre組換え酵素による染色体間組換え頻度測定により明らかとなったテロメア近傍遺伝子のアクセシビリティー2010
- Author(s)
  植村宗弘, 丹羽陽子, 嘉数直樹、足立典隆、木下和生
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-20590326
[Presentation] A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.2009
- Author(s)
  Takai A, Toyoshima T, Uemura M, Niwa Y, Marusawa H, Hiai H, Honjo T, Chiba T, Kinoshita K
- Organizer
  21st IUBMB and 12th EAOBMB International Congress of Biochemistry and Molecular Biology.
- Place of Presentation
  上海(中国)
- Year and Date
  2009-08-06
- Data Source
  KAKENHI-PROJECT-17013042
[Presentation] A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.2009
- Author(s)
  Takai A, Toyoshima T, Uemura M, Niwa Y, Marusawa H, Hiai H, Honjo T, Chiba T, Kinoshita K.
- Organizer
  21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology.
- Place of Presentation
  上海, 中国
- Data Source
  KAKENHI-PROJECT-17013042
[Presentation] Chromosomal manipulation by site-specific recombinases and fluorescent protein-based vectors.2009
- Author(s)
  植村宗弘, 丹羽陽子, 嘉数直樹, 足立典隆, 木下和生.
- Organizer
  21st IUBMB and 12th FAOBMB International Congress of Biochemistry and Molecular Biology
- Place of Presentation
  上海(中国)
- Year and Date
  2009-08-09
- Data Source
  KAKENHI-PROJECT-20590326
[Presentation] 部位特異的組換え酵素と蛍光タンパクを用いた染色体手術法の開発2009
- Author(s)
  植村宗弘、丹羽陽子、嘉数直樹、足立典隆、木下和生
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-09
- Data Source
  KAKENHI-PROJECT-20590326
[Presentation] Cre-loxP 組換え系と蛍光タンパクを用いた遺伝子間3次元的距離の測定2008
- Author(s)
  植村宗弘, 足立典隆, 木下和生
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20590326
[Presentation] 内在性変異原AIDによる抗体とがん細胞の進化2008
- Author(s)
  木下和生
- Organizer
  第80回日本遺伝学会大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17013042
[Presentation] A new mouse model of hepatocarcinogenesis triggered by activation-induced cytidine deaminase expressed in hepatic stem cells.2008
- Author(s)
  Takai A, Marusawa H, Tabuchi Y, Ohtsuru S, Endo Y, Chiba T, Kinoshita K.
- Organizer
  AACR Annual Meeting
- Place of Presentation
  San Diego, U.S.A.
- Year and Date
  2008-04-12
- Data Source
  KAKENHI-PROJECT-17013042
[Presentation] 発癌過程における遺伝子異常生成へのActivation-induced cytidine deaminase (AID)の関与2008
- Author(s)
  遠藤容子、丸澤宏之、木下和生、本庶佑、千葉勉
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-17013042
[Presentation] Activation- induced cytidine deaminase serves as a link between inflammation to colitis- associated colorectal cancers.2008
- Author(s)
  Endo Y, Marusawa H, Kinoshita K, Kou T, Fujii S, Fujimori T, Chiba T.
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-17013042
[Presentation] Cre-loxP組換え系と蛍光タンパクを用いた遺伝子間3次元的距離の測定2008
- Author(s)
  植村宗弘、足立典隆、木下和生
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20590326
[Presentation] 突然変異誘導因子AIDによる発がん2005
- Author(s)
  木下和生, 野中太一郎
- Organizer
  第64回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-17013042

1. SONOBE Makoto (00432378)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. UEMURA Munehiro (30568390)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. 村松正道

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. MIYAHARA Ryo (20335285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAGAI Shinjiro (50447984)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. IKUTA Koichi (90193177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANIGUCHI Yoshihito (00324616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KUROOKA Hisanori (00293879)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TOKUHISA Takeshi (20134364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 竹森利忠 (60114295)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 坂本明美 (90359597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 金井理紗 (50935947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. シドニアファガラサン

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KITAMURA Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. WAKAE kousho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. WATANABE Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 丸澤宏之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 木下芳一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 千葉勉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kinoshita Kazuo 木下 和生

木下 和生 キノシタ カズオ

KINOSHITA Kazuo 木下 和生

Research Projects

Research Products

Co-Researchers

TTC7A欠損に起因する難治性腸閉鎖症のパラログ遺伝子発現促進による治療

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Elucidation of erythroid differentiation using fsn micePrincipal Investigator

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Carcinogenesis by a mutagenic enzyme AIDPrincipal Investigator

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Mechanisms of diseases by chromosomal translocationPrincipal Investigator

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Is activation-induced cytidine deaminase related to oncogenesis of lung cancer with induction of gene mutations observed in lung cancer?

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Interaction between endogeneous mutator AID and exogenous oncogenic factors in carcinogenesisPrincipal Investigator

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Carcinogenesis by a genome mutator AIDPrincipal Investigator

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発がんにおける内在的突然変異誘導因子と外的因子の相互作用解析モデルの構築Principal Investigator

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Interaction between endogenous mutator AID and exogenous oncogenic factors in carcinogenesisPrincipal Investigator

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精子形成における突然変異誘導機構の探索Principal Investigator

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Study for Development and Maintenance of mune Memory

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RNA編集による抗体遺伝子のDNA情報変換機構Principal Investigator

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RNA編集による抗体遺伝子のDNA情報変換機構Principal Investigator

Principal Investigator

Kinoshita Kazuo 木下和生

木下和生キノシタカズオ

KINOSHITA Kazuo 木下和生