Mizuta Ryushin 水田龍信

… Alternative Names

MIZUTA Ryushin 水田龍信

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Researcher Number	50297628
Other IDs
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Affiliation (Current)	2025: 東京理科大学, 研究推進機構生命医科学研究所, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京理科大学, 研究推進機構生命医科学研究所, 教授 2019: 東京理科大学, 研究推進機構生命医科学研究所, 教授 2017 – 2018: 東京理科大学, 研究推進機構生命医科学研究所, 准教授 2012 – 2014: 東京理科大学, 生命医科学研究所, 准教授 2011: 東京理科大学, 生命科学研究所, 准教授 … More 2010: 東京理科大学, 生命科学研究所, 洵教授 2009: Tokyo University of Science, 生命科学研究所, 准教授 2003 – 2004: 東京理科大学, 生命科学研究所, 講師 1998 – 1999: 東京理科大学, 生命科学研究所, 講師 Less
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49070:Immunology-related / Molecular biology
Keywords	Principal Investigator XRCC4 / DNase1L3 / ネクローシス / cfDNA / DNase γ / ubiquitin C-terminal hydrolase / V(D)J recombination / RAG2 / proteasome / ubiquitin … More / RAB22 / RAD51 / アポトーシス / 酸化ストレス / DNA断片化 / ヌクレオソーム / 樹状細胞 / 免疫賦活 / HMGN1 / ヘテロクロマチン / DNase１ / Histone H1 / クロマチン / 抗腫瘍効果 / 相分離 / DNase 1 / 免疫学 / 細胞 / 癌 / 核酸 / 遺伝子 / 好中球 / DNase1 / DNase1l3 / NET / DNaseⅠ / liquid biopsy / DNase I / DNaseγ / liquide biopsy / NETS / CAD / AID / ユビチキン / プロテオソーム / ユビキチン / Recombination / DNA組換え / ＴＵＮＥＬ / アセトアミノフェン / ＤＮＡ断片化 / SLE / 自己免疫疾患 / 無菌的炎症 Less

Elucidation of the mechanism of immune activation by DNase1L3Principal Investigator
- Principal Investigator
  
  水田龍信
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tokyo University of Science
Elucidation of spatiotemporal control mechanism of dead cell DNA degrading enzymes by phase separationPrincipal Investigator
- Principal Investigator
  
  Mizuta Ryushin
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tokyo University of Science
Mechanisms of dead cell DNA degradation and cell-free DNA generationPrincipal Investigator
- Principal Investigator
  
  Mizuta Ryushin
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
Significance of necrosis DNA fragmentation under oxidative stress and immune responsePrincipal Investigator
- Principal Investigator
  
  MIZUTA RYUSHIN
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
NECROTIC DNA FRAGMENTATION AND ASEPTIC INFLAMMATIONPrincipal Investigator
- Principal Investigator
  
  MIZUTA Ryushin
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo University of Science
Regulation of immune recombination by ubiquitin-proteasome systemPrincipal Investigator
- Principal Investigator
  
  MIZUTA Ryushin
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  TOKYO UNIVERSITY OF SCIENCE
Functional Analysis of the recombination protein RAD51 and its associated molecules.Principal Investigator
- Principal Investigator
  
  MIZUTA Ryushin
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Science University of Tokyo

All 2023 2022 2020 2019 2018 2017 2014 2013 2012 2011 2010 2009 2004 2003 Other

All Journal Article Presentation

[Journal Article] DNASE1L3 enhances antitumor immunity and suppresses tumor progression in colon cancer2023
- Author(s)
  Li Wenling、Nakano Hideki、Fan Wei、Li Yuanyuan、Sil Payel、Nakano Keiko、Zhao Fei、Karmaus Peer W.、Grimm Sara A.、Shi Min、Xu Xin、Mizuta Ryushin、Kitamura Daisuke、Wan Yisong、Fessler Michael B.、Cook Donald N.、Shats Igor、Li Xiaoling、Li Leping
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 17
- DOI
  10.1172/jci.insight.168161
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07086
[Journal Article] The difference of chows affects mouse physiological conditions2022
- Author(s)
  WATANABE Taiki、TAKADA Shuhei、ONOZATO Mayu、FUKUSHIMA Takeshi、MIZUTA Ryushin
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 84 Issue: 4 Pages: 582-584
- DOI
  10.1292/jvms.21-0457
- NAID
  130008159734
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07086
[Journal Article] Linker histone H1 determines cell stiffness and differentiation.2020
- Author(s)
  Kijima M, Yamagish H, Kawano R, Konishi T, Okumura T, Hayase M, Mizuta R.
- Journal Title
  
  BioRxiv
  
  Volume: －
- DOI
  10.1101/2020.01.21.914770
- Open Access
- Data Source
  KAKENHI-PROJECT-17K08891
[Journal Article] DNase γ-dependent DNA fragmentation causes karyolysis in necrotic hepatocyte2020
- Author(s)
  Takada S, Watanabe T, Mizuta R.
- Journal Title
  
  Journal of Veterinary Medical Science
  
  Volume: 82 Issue: 1 Pages: 23-26
- DOI
  10.1292/jvms.19-0499
- NAID
  130007783762
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08891
[Journal Article] 細胞死におけるDNase γの役割2019
- Author(s)
  水田龍信
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 71 Pages: 114-119
- Data Source
  KAKENHI-PROJECT-17K08891
[Journal Article] Cell-free DNA in blood circulation is generated by DNase1L3 and caspase-activated DNase.2019
- Author(s)
  Watanabe T, Takada S, Mizuta R.
- Journal Title
  
  BIOCHEM. BIOPH. RES. CO.
  
  Volume: 516 Issue: 3 Pages: 790-795
- DOI
  10.1016/j.bbrc.2019.06.069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08891
[Journal Article] Histone H1 quantity determines the efficiency of chromatin condensation in both apoptotic and live cells2019
- Author(s)
  Marie Kijima, Hiroyuki Yamagishi, Yasushi Hara, Mai Kasai, Yasunari Takami, Hiroshi Takemura, Yusuke Miyanari, Yoichi Shinkai, Ryushin Mizuta
- Journal Title
  
  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
  
  Volume: 512 Issue: 2 Pages: 202-207
- DOI
  10.1016/j.bbrc.2019.03.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08891, KAKENHI-PROJECT-15H05586
[Journal Article] 2018年ノーベル生理学・医学賞　免疫抑制解除による新規がん治療法の開発2019
- Author(s)
  水田龍信
- Journal Title
  
  理大科学フォーラム
  
  Volume: 36 Pages: 28-29
- Data Source
  KAKENHI-PROJECT-17K08891
[Journal Article] 細胞死に学ぶ生体の「もの壊し」の知恵と疾患ーDNAはいかにして分解されていくか2018
- Author(s)
  水田龍信
- Journal Title
  
  理大科学フォーラム
  
  Volume: 35 Pages: 34-39
- NAID
  40021694688
- Data Source
  KAKENHI-PROJECT-17K08891
[Journal Article] Host DNases prevent vascular occlusion by neutrophil extracellular traps2017
- Author(s)
  Jimenez-Alcazar Miguel、Rangaswamy Chandini、Panda Rachita、Bitterling Josephine、Simsek Yashin J.、Long Andy T.、Bilyy Rostyslav、Krenn Veit、Renn? Christoph、Renn? Thomas、Kluge Stefan、Panzer Ulf、Mizuta Ryushin、Mannherz Hans Georg、Kitamura Daisuke、Herrmann Martin、Napirei Markus、Fuchs Tobias A.
- Journal Title
  
  Science
  
  Volume: 358 Issue: 6367 Pages: 1202-1206
- DOI
  10.1126/science.aam8897
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08891, KAKENHI-PUBLICLY-17H05803, KAKENHI-PROJECT-16H05206, KAKENHI-PROJECT-16K15295
[Journal Article] Acrolein, a highly toxic aldehyde generated under oxidative stress in vivo, aggravates the mouse liver damage after acetaminophen overdose.2014
- Author(s)
  Arai, T., Koyama, R., Yuasa, M., Kitamura, D., Mizuta, R.
- Journal Title
  
  BIOMEDICAL RESEARCH-TOKYO
  
  Volume: ３５ Pages: 389-395
- NAID
  130004903866
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590587
[Journal Article] DNase γ Is the Effector Endonuclease for Internucleo- somal DNA Fragmentation in Necrosis2013
- Author(s)
  Mizuta R., Araki S., Furukawa M., Furukawa Y., Ebara S., Shiokawa D., Hayashi K., Tanuma S., and Kitamura D
- Journal Title
  
  PLoS One
  
  Volume: 8(12) Issue: 12 Pages: 1-8
- DOI
  10.1371/journal.pone.0080223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300365, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24590587, KAKENHI-PROJECT-24659225, KAKENHI-PUBLICLY-25111512, KAKENHI-PUBLICLY-25118730, KAKENHI-PROJECT-25293116, KAKENHI-PROJECT-25460156
[Journal Article] ウシ乳房炎と乳汁中HMGB1蛋白2013
- Author(s)
  水田龍信、菊佳男、尾澤知美、菅原和恵、林智人
- Journal Title
  
  日本乳房炎研究会 proceedings
  
  Volume: 17
- Data Source
  KAKENHI-PROJECT-24590587
[Journal Article] ウシ乳房炎と乳汁中HMGB1蛋白2013
- Author(s)
  水田龍信、菊佳男、尾澤知美、菅原和恵、林智人
- Journal Title
  
  日本乳房炎研究会Proceedings
  
  Volume: １７ Pages: 81-83
- Data Source
  KAKENHI-PROJECT-24590587
[Journal Article] 乳汁中HMGB1蛋白量はウシ乳房炎重症度と相関する。2012
- Author(s)
  水田龍信、菊佳男、尾澤知美、松原朋子、林智人
- Journal Title
  
  日本乳房炎研究会 proceedings
  
  Volume: 16 Pages: 29-31
- Data Source
  KAKENHI-PROJECT-24590587
[Journal Article] 乳汁中HMGB1蛋白量はウシ乳房炎重症度と相関する2012
- Author(s)
  水田龍信
- Journal Title
  
  日本乳房炎研究会(第16回学術集会)Proceedings
  
  Pages: 29-31
- Data Source
  KAKENHI-PROJECT-21590542
[Journal Article] Increased concentration of high-mobility-group box 1(HMGB1) protein in milk is related to the severity of bovine mastitis2011
- Author(s)
  Furukawa, Y., Hayashi, T., Mizuta, M., Ebara, S., Kiku, Y., Ozawa, T., Matsubara, T., Ito, I., Kitamura, D., Mizuta, R.
- Journal Title
  
  Vet Res Commun
  
  Volume: 35 Pages: 47-54
- Data Source
  KAKENHI-PROJECT-21590542
[Journal Article] Transcribed Guanine-rich RNA Aggregates on Template DNA and Changes Its Conformation.2010
- Author(s)
  水田龍信
- Journal Title
  
  Chemistry Letter
  
  Volume: 39 Pages: 1088-1089
- NAID
  10027185890
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590542
[Journal Article] Transcribed Guanine-rich RNA Aggregates on Template DNA and Changes Its Conformation2010
- Author(s)
  Mizuta, R.
- Journal Title
  
  Chemistry Letters
  
  Volume: 39 Pages: 1088-1089
- NAID
  10027185890
- Data Source
  KAKENHI-PROJECT-21590542
[Journal Article] DNaseγ-dependent and-independent apoptotic DNA fragmentations in Ramos Burkitt's lymphoma cell line2009
- Author(s)
  Mizuta, R., Mizuta, M., Araki, S., Suzuki, K., Ebara, S., Furukawa, Y., Shiokawa, D., Tanuma, S., Kitamura, D
- Journal Title
  
  BIOMEDICAL RESEARCH
  
  Volume: 30 Pages: 165-170
- Data Source
  KAKENHI-PROJECT-21590542
[Journal Article] Possible contribution of Dnaseγto immunoglobulin V gene diversification2009
- Author(s)
  Okamoto, N., Okamoto, M., Araki, S., Arakawa, H., Mizuta, R., Kitamura, D.
- Journal Title
  
  Immunology Letters
  
  Volume: 125 Pages: 22-30
- Data Source
  KAKENHI-PROJECT-21590542
[Journal Article] DNase γ-dependent and -independent apoptotic DNA fragmentations in Ramos Burkitt's lymphoma cell line2009
- Author(s)
  水田龍信
- Journal Title
  
  BIOMEDICAL RESEARCH 30
  
  Pages: 165-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590542
[Journal Article] 免疫グロブリンクラススイッチとS領域転写2004
- Author(s)
  水田龍信
- Journal Title
  
  臨床免疫 42
  
  Pages: 251-254
- NAID
  40006398262
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590442
[Journal Article] Immunoglobulin class switch and S region transcription2004
- Author(s)
  Mizuta, R.
- Journal Title
  
  RINSHO MENEKI 42
  
  Pages: 251-254
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590442
[Journal Article] Mechanism of V(D)J recombination2003
- Author(s)
  Mizuta, R.
- Journal Title
  
  RINSHO MENEKI 40
  
  Pages: 73-79
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590442
[Journal Article] 抗原レセプターVDJ組換えの機序2003
- Author(s)
  水田龍信
- Journal Title
  
  臨床免疫 40
  
  Pages: 73-79
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590442
[Presentation] 血液中cell-free DNA 生成のメカニズムの解明.2019
- Author(s)
  水田龍信、渡邊大樹、高田周平
- Organizer
  第28回日本Cell Death 学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08891
[Presentation] 餌の違いによる薬剤感受性の違いとその原因の解明.2019
- Author(s)
  渡邊太樹、高田周平、小野里磨優、福島健、水田龍信
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08891
[Presentation] 肝細胞死におけるcell-free DNA生成のメカニズム.2019
- Author(s)
  水田龍信、渡邊大樹、高田周平
- Organizer
  第26回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-17K08891
[Presentation] DNase1L3とCaspase-activated DNaseがcell-free DNAを生成する.2019
- Author(s)
  高田周平、渡邊大樹、水田龍信
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08891
[Presentation] ネクローシス下のcell-free DNA 生成におけるDNase γの関与2018
- Author(s)
  渡邊大樹、木島真理恵、河野莉穂、高田周平、水田龍信
- Organizer
  第27回日本Cell Death 学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08891
[Presentation] DNase γはネクローシスの際のcell-free DNA生成に主要な役割を担う2018
- Author(s)
  渡邊大樹、高田周平、木島真理恵、河野莉穂、水田龍信
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08891
[Presentation] 肝細胞死におけるcell-free DNA 生成のメカニズム2018
- Author(s)
  水田龍信、渡邊大樹、高田周平、木島真理恵、河野莉穂
- Organizer
  第25回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-17K08891
[Presentation] 細胞死DNA断片化とクロマチン凝集の生成メカニズムと生理的意義2017
- Author(s)
  木島真理恵、河野莉穂、渡邊太樹、水田龍信
- Organizer
  ２０１７年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K08891
[Presentation] 肝細胞ネクローシスにおけるcell-free DNA生成のメカニズム2017
- Author(s)
  水田龍信、木島真理恵、河野莉穂
- Organizer
  第２４回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-17K08891
[Presentation] DNA断片化とクロマチン凝集の生成メカニズムと生理的意義2017
- Author(s)
  水田龍信、木島真理恵、河野莉穂, 渡邊太樹
- Organizer
  第26回日本Cell Death 学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08891
[Presentation] 肝臓におけるネクローシスＤＮＡ断片化のメカニズム2014
- Author(s)
  水田龍信
- Organizer
  第21回肝細胞研究会
- Place of Presentation
  東京医科歯科大学（東京）
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-24590587
[Presentation] Identification of Necrotic DNA Fragmentation2014
- Author(s)
  荒井智也、水田龍信、北村大介
- Organizer
  ISTC2014
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590587
[Presentation] ネクローシスＤＮＡ断片化のメカニズム2014
- Author(s)
  水田龍信,小山諒
- Organizer
  第23回日本Cell Death学会
- Place of Presentation
  東京医科歯科大学（東京）
- Year and Date
  2014-07-18
- Data Source
  KAKENHI-PROJECT-24590587
[Presentation] DNase γとDNase IによるネクローシスDNA断片化2014
- Author(s)
  水田龍信、小山諒、北村大介
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-24590587
[Presentation] DNAによる核の堅牢性、脆弱性の制御-薬剤性肝障害を例として2012
- Author(s)
  水田龍信
- Organizer
  第3回バイオメディカルインターフェース・ワークショップ
- Place of Presentation
  宮古島公民館(宮古島)
- Year and Date
  2012-02-25
- Data Source
  KAKENHI-PROJECT-21590542
[Presentation] Regulation of oxidative stress and tumorigenesis2011
- Author(s)
  水田龍信
- Organizer
  International Symposium on Technologies against Cancer 2011
- Place of Presentation
  Tokyo/Tower Hall Funabori
- Year and Date
  2011-09-02
- Data Source
  KAKENHI-PROJECT-21590542
[Presentation] 肝細胞死におけるDNA断片化酵素の役割2011
- Author(s)
  水田龍信
- Organizer
  第18回肝細胞研究会
- Place of Presentation
  東京ガーデンパレス(東京)
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-21590542
[Presentation] 乳汁中HMGB1蛋白量はウシ乳房炎重症度と相関する2011
- Author(s)
  水田龍信
- Organizer
  第16回日本乳房炎研究会学術集会
- Place of Presentation
  つくば国際会議場(筑波)
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-21590542
[Presentation] DNA断片化と細胞核の分解2011
- Author(s)
  水田龍信
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21590542
[Presentation] 乳汁中HMGB1蛋白量はウシ乳房炎重症度と相関する2011
- Author(s)
  水田龍信
- Organizer
  第152回日本獣医学会学術集会
- Place of Presentation
  大阪府立大学(大阪)
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-21590542
[Presentation] DNAによる核の堅牢性、脆弱性の制御2011
- Author(s)
  水田龍信
- Organizer
  日本生化学会関東支部例会
- Place of Presentation
  東京理科大学森戸記念館(東京)(招待講演)
- Year and Date
  2011-06-25
- Data Source
  KAKENHI-PROJECT-21590542
[Presentation] DNA断片化と細胞核の分解2011
- Author(s)
  水田龍信、三沢正行、荒井智也、北村大介
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21590542
[Presentation] 乳汁中HMGB1蛋白量はウシ乳房炎重症度と相関する2011
- Author(s)
  水田龍信、菊佳男、尾澤知美、松原朋子、林智人
- Organizer
  第16回日本乳房炎研究会学術集会
- Place of Presentation
  筑波
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-21590542
[Presentation] DNA断片化と細胞核の分解2009
- Author(s)
  水田龍信
- Organizer
  第32回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-21590542
[Presentation] ウシ乳房炎と乳汁中HMGB1蛋白
- Author(s)
  水田龍信、菊佳男、尾澤知美、菅原和恵、林智人
- Organizer
  17回日本乳房炎研究会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590587
[Presentation] 破壊の生物学
- Author(s)
  水田龍信
- Organizer
  2013 Biomedical Interface Satellite Workshop
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-24590587
[Presentation] DNA 断片化による肝細胞酸化ストレス抑制機構
- Author(s)
  水田龍信
- Organizer
  第19回肝細胞研究会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24590587
[Presentation] ネクローシスにおけるDNA断片化酵素の生理的役割
- Author(s)
  荒井智也、小山諒、木島真理恵、北村大介、水田龍信
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590587
[Presentation] Identification of necrotic DNA fragmentation
- Author(s)
  水田龍信、荒井智也、北村大介
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24590587
[Presentation] アクロレインによる薬剤性肝障害の増悪
- Author(s)
  小山諒、荒井智也、木島真理恵、北村大介、水田龍信
- Organizer
  第36回日本分子生物学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24590587

1. 北村大介 (70204914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. 田沼靖一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mizuta Ryushin 水田 龍信

MIZUTA Ryushin 水田 龍信

Research Projects

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Elucidation of the mechanism of immune activation by DNase1L3Principal Investigator

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Elucidation of spatiotemporal control mechanism of dead cell DNA degrading enzymes by phase separationPrincipal Investigator

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Mechanisms of dead cell DNA degradation and cell-free DNA generationPrincipal Investigator

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Significance of necrosis DNA fragmentation under oxidative stress and immune responsePrincipal Investigator

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NECROTIC DNA FRAGMENTATION AND ASEPTIC INFLAMMATIONPrincipal Investigator

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Regulation of immune recombination by ubiquitin-proteasome systemPrincipal Investigator

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Functional Analysis of the recombination protein RAD51 and its associated molecules.Principal Investigator

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[Journal Article] DNASE1L3 enhances antitumor immunity and suppresses tumor progression in colon cancer2023

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[Journal Article] The difference of chows affects mouse physiological conditions2022

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[Journal Article] Linker histone H1 determines cell stiffness and differentiation.2020

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[Journal Article] DNase γ-dependent DNA fragmentation causes karyolysis in necrotic hepatocyte2020

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[Journal Article] 細胞死におけるDNase γの役割2019

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[Journal Article] Cell-free DNA in blood circulation is generated by DNase1L3 and caspase-activated DNase.2019

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Mizuta Ryushin 水田龍信

MIZUTA Ryushin 水田龍信

[Journal Article] 2018年ノーベル生理学・医学賞　免疫抑制解除による新規がん治療法の開発2019