Kai Nobuyuki 甲斐信行

… Alternative Names

KAI Nobuyuki 甲斐信行

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Researcher Number	50301750
Other IDs
Affiliation (Current)	2025: 獨協医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2016 – 2023: 獨協医科大学, 医学部, 助教 2012 – 2013: 獨協医科大学, 医学部, 助教 2007 – 2011: Fukushima Medical University, 医学部, 助教 2009: 公立大学法人福島県立医科大学, 医学部, 助教 2007: 医学部, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 51020:Cognitive and brain science-related / Psychiatric science / Neuroscience in general / Nerve anatomy/Neuropathology Except Principal Investigator General anatomy (including Histology/Embryology) / Neuroscience in general
Keywords	Principal Investigator 側坐核 / 海馬 / ドパミン / ラット / イムノトキシン細胞標的法 / ドーパミン / 情動 / 記憶 / 敵対行動 / 非言語コミュニケーション … More / カイロモン / フェロモン / 記憶固定化 / 記憶の上書き / 条件づけ場所嗜好性 / 快情動 / 前嗅核 / セロトニン / 捕食者 / 社会性記憶 / 社会的動機づけ / 報酬系 / 依存・嗜癖 / Cre-loxP法 / GABA作動性ニューロン / 嗜癖 / 依存 / オプトジェネティックス / 腹側淡蒼球 / ギャンブリング課題 / 意思決定 / 行動実験 / ドパミンD2受容体 / 側坐核コア / 選択行動 / 神経行動学 / イムノトキシン / 対応法則 / マッチング / スイッチング / 自発的回復 / 強化後休止 / 交代反応 / オペラントマッチング / マッチング行動 / マッチングの法則 / ドーパミン受容体 / 神経回路網 / ドパミン受容体 / 報酬行動 … More Except Principal Investigator 脳・神経 / 発生・分化 / 細胞・組織 / マイクロアレイ / 神経科学 / 派生・分化 / 神経発生 / 運動制御 / 遺伝子改変マウス / ドーパミンD1受容体 / 強化学習 / イムノトキシン細胞標的法 / 遺伝子改変動物 / 神経活動 / ドーパミン受容体 / ドーパミン伝達 / 投射ニューロン / 線条体 / 学習 Less

快情動を伴ったエピソード記憶の維持・強化メカニズムの解明Principal Investigator
- Principal Investigator
  
  甲斐信行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Dokkyo Medical University
Mechanisms of Social Motivation Formation via the Sense of SmellPrincipal Investigator
- Principal Investigator
  
  Kai Nobuyuki
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51020:Cognitive and brain science-related
- Research Institution
  Dokkyo Medical University
An analysis of the neural basis of risky choice in the rat gambling task.Principal Investigator
- Principal Investigator
  
  Kai Nobuyuki
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Dokkyo Medical University
Roles of the nucleus accumbens core on development of matching behaviorPrincipal Investigator
- Principal Investigator
  
  KAI Nobuyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Dokkyo Medical University
  Fukushima Medical University
Analyses of novel genes expressed in the embryonic spinal cord with reference to the sensory axonal guidance
- Principal Investigator
  
  MASUDA Tomoyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Fukushima Medical University
Neural circuit mechanisms of behavioral control through striatal projection pathways
- Principal Investigator
  
  KOBAYASHI Kazuto
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  Fukushima Medical University
Analysis of neural circuits in reward-related behaviorsPrincipal Investigator
- Principal Investigator
  
  KAI Nobuyuki
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Fukushima Medical University
Identification of novel axonal guidance cues in the mouse embryo
- Principal Investigator
  
  MASUDA Tomoyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Fukushima Medical University

All 2021 2020 2017 2014 2012 2011 2010 2009 2008 2007

All Journal Article Presentation Book

[Book] Functional circuitry analysis in rodents using neurotoxins/ immuno- toxins. In Neuromethods, Controlled Genetic Manipulations chapter 102012
- Author(s)
  Kobayashi K, Okada K, Kai N
- Publisher
  Humana Press Inc., New York
- Data Source
  KAKENHI-PROJECT-22500294
[Journal Article] Induction of aberrant agonistic behavior by a combination of serotonergic and dopaminergic manipulation in rats2021
- Author(s)
  Kai Nobuyuki、Ueda Shuichi
- Journal Title
  
  Brain Structure and Function
  
  Volume: 226 Issue: 4 Pages: 1253-1267
- DOI
  10.1007/s00429-021-02238-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07805
[Journal Article] Lesions of the nucleus accumbens core modulate development of matching behavior2014
- Author(s)
  Kai N, Tsusui Y, Kobayashi K
- Journal Title
  
  BMC Neuroscience 2014
  
  Volume: 15 Issue: 1 Pages: 55-55
- DOI
  10.1186/1471-2202-15-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500294, KAKENHI-PLANNED-26112002, KAKENHI-PUBLICLY-26120720
[Journal Article] Lesions of the nucleus accumbens core modulate development of matching behavior2014
- Author(s)
  Nobuyuki Kai, Yuji Tsutsui, Kazuto Kobayashi
- Journal Title
  
  BMC Neuroscience
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500294
[Journal Article] Rho/Rho-kinase signaling pathway controls axon patterning of a specified subset of cranial motor neurons.2011
- Author(s)
  Kenta Kobayashi, Tomoyuki Masuda, Masanori Takahashi, Junichi Miyazaki, Masahiro Nakagawa, Motokazu Uchigashima, Masahiko Watanabe, Hiroyuki Yaginuma, Noriko Osumi, Kozo Kaibuchi, Kazuto Kobayashi
- Journal Title
  
  European Jourbal of Neuroscience
  
  Volume: 33 Pages: 612-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590218
[Journal Article] Lever pressing responses under a fixed-ratio schedule of mice with 6-hydroxydopamine-induced dopamine depletion in the nucleus accumbens2011
- Author(s)
  甲斐信行
- Journal Title
  
  Behav Brain Res
  
  Volume: 217(1) Pages: 60-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500294
[Journal Article] Lever pressing responses under a fixed-ratio schedule of mice with 6-hydroxydopamine -induced dopamine depletion in the nucleus accumbens2011
- Author(s)
  Tsutsui Y, Nishizawa K, Kai N, Kobayashi K
- Journal Title
  
  Behavioural Brain Research
  
  Volume: 217 Issue: 1 Pages: 60-66
- DOI
  10.1016/j.bbr.2010.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500294
[Journal Article] Rho/Rho-kinase signaling pathway controls axon patterning of a specified subset of cranial motor neurons2011
- Author(s)
  Kenta Kobayashi, Tomoyuki Masuda, Masanori Takahashi, Jun-ichi Miyazaki, Masahiro Nakagawa, Motokazu Uchigashima, Masahiko Watanabe, Hiroyuki Yaginuma, Noriko Osumi, Kozo Kaibuchi, Kazuto Kobayashi
- Journal Title
  
  European Journal of Neuroscience
  
  Volume: 33(4) Pages: 612-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590218
[Journal Article] Up-regulation of dopamine D 1 receptor in the hippocampus after establishment of conditioned place preference by cocaine.2011
- Author(s)
  Tanaka, T., Kai, N., Kobayashi, K., Takano, Y., Hironaka, N.
- Journal Title
  
  Neuropharmacology
  
  Volume: 61 Issue: 4 Pages: 842-848
- DOI
  10.1016/j.neuropharm.2011.05.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500294
[Journal Article] 道具的学習と行動制御を研究するモデル実験動物2010
- Author(s)
  小林和人, 深堀良二, 甲斐信行, 岡田佳奈, 小林とも子
- Journal Title
  
  生体の科学 Vol.61,No.1
  
  Pages: 47-52
- Data Source
  KAKENHI-PROJECT-19300109
[Journal Article] Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.2009
- Author(s)
  Masuda T, Kai N, Sakuma C, Kobayashi K, Koga H, Yaginuma H.
- Journal Title
  
  Brain Res. 1249
  
  Pages: 61-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500297
[Journal Article] Laser capture microdissection and cDNA analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.2009
- Author(s)
  Masuda T, Kai N, Sakuma C, Kobayashi K, Koga H, Yaginuma H.
- Journal Title
  
  Brain Research 1249
  
  Pages: 61-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590191
[Journal Article] Laser capture microdissection and cDNA analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord2009
- Author(s)
  Tomoyuki Masuda, Nobuyuki Kai, Chie Sakuma, Kazuto Kobayashi, Hisashi Koga, Hiroyuki Yaginuma
- Journal Title
  
  Brain Res 1249
  
  Pages: 61-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590191
[Journal Article] ドーパミン伝達による行動発現システムの制御2008
- Author(s)
  甲斐信行、小林和人
- Journal Title
  
  蛋白質核酸酵素 53
  
  Pages: 565-572
- Data Source
  KAKENHI-PROJECT-19300109
[Journal Article] Selective loss of nigral dopamine neurons induced by overexpression of truncated human a-synuclein in mice.2008
- Author(s)
  Wakamatsu, M., Ishii, A., Iwata, S., Sakagami, J., Ukai, Y., Ono, M., Kanbe, D., Muramatsu, S.I., Kobayashi, K., Iwatsubo, T., Yoshimoto, M.
- Journal Title
  
  Neurobiol. Aging 29(4)
  
  Pages: 574-585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300109
[Journal Article] 基底核と記憶2008
- Author(s)
  甲斐信行, 小林和人
- Journal Title
  
  分子精神医学 8
  
  Pages: 294-299
- Data Source
  KAKENHI-PROJECT-19500297
[Journal Article] ドーパミン伝達による行動発現システムの制御2008
- Author(s)
  甲斐信行, 小林和人
- Journal Title
  
  蛋白質・核酸・酵素 53
  
  Pages: 565-572
- Data Source
  KAKENHI-PROJECT-19500297
[Journal Article] Transient silencing of synaptic transmitter release from specific neuronal types by recombinant tetanus toxin light chain fused to antibody variable region.2008
- Author(s)
  Kobayashi T, Kai N, Kobayashi K, Fujiwara T, Akagawa K, Onda M, Kobayashi K.
- Journal Title
  
  J Neurosci Methods. Vol.175,No1
  
  Pages: 125-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500297
[Journal Article] 基底核と記憶2008
- Author(s)
  甲斐信行, 小林和人
- Journal Title
  
  分子精神医学 8
  
  Pages: 10-15
- Data Source
  KAKENHI-PROJECT-19300109
[Journal Article] ドーパミン伝達による行動発現システムの制御2008
- Author(s)
  甲斐信行, 小林和人
- Journal Title
  
  蛋白質核酸酵素(増刊号:神経の分化、回路形成、機能発現) Vol.53,No.4
  
  Pages: 565-572
- Data Source
  KAKENHI-PROJECT-19300109
[Journal Article] Transient silencing of synaptic transmitter release from specific neuronal types by recombinant tetanus toxin light chain fused to antibody variable region.2008
- Author(s)
  Kobayashi, T., Kai, N., Kobayashi, K., Fujiwara, T., Akagawa, I., Onda, M., Kobayashi, K.
- Journal Title
  
  J. Neurosci. Methods 175(1)
  
  Pages: 125-132
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19300109
[Presentation] モノアミン神経伝達を介した敵対行動に関わる脳部位の解析2020
- Author(s)
  甲斐信行
- Organizer
  第125回　日本解剖学会総会・全国学術集塊
- Data Source
  KAKENHI-PROJECT-19K07805
[Presentation] モノアミン神経操作により誘発される行動異常に関連した脳領域の探索2017
- Author(s)
  甲斐信行、江原鮎香、上田秀一
- Organizer
  第9回　光操作研究会
- Data Source
  KAKENHI-PROJECT-16K10256
[Presentation] The development of operant matching is regulated by the Nucleus Accumbens core.2011
- Author(s)
  Kai N., Kobayashi K.
- Organizer
  The Society for Neuroscience annual meeting
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-22500294
[Presentation] The development of operant matching is regulated by the Nucleus Accumbens core2011
- Author(s)
  Kai N, Tsutsui Y, Kobayashi K
- Organizer
  第34回日本神経科学大会2011
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22500294
[Presentation] The development of operant matching is regulated by the Nucleus Accumbens core.2011
- Author(s)
  Kai N., Tsutsui Y., Kobayashi K.
- Organizer
  he 34th Annual Meeting of Japan Neuroscience Society
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-22500294
[Presentation] The development of operant matching is regulated by the Nucleus Accumbens core2011
- Author(s)
  Kai N, Kobayashi K
- Organizer
  The Society for Neuroscience annual meeting
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-22500294
[Presentation] The role of dopamine D2 receptor-expressing neurons in the nucleus accumbens core in operant matching2010
- Author(s)
  甲斐信行
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22500294
[Presentation] レーザーマイクロダイセクション法を用いた, 発生初期マウス胚脊髄およびその周囲に優位に発現する分子の検索2009
- Author(s)
  増田知之, 佐久間千恵, 甲斐信行, 古閑久佐志, 八木沼洋行
- Organizer
  第113回日本解剖学会全国学術集会
- Place of Presentation
  大分
- Year and Date
  2009-03-29
- Data Source
  KAKENHI-PROJECT-19590191
[Presentation] Implication of hippocampal dopamine in the conditioning of the rewarding effect of cocaine.2009
- Author(s)
  Tanaka T, Kai N, Kobayashi K, Hironaka N.
- Organizer
  39th Annual Meeting of Society for Neuroscience
- Place of Presentation
  Chicago.
- Data Source
  KAKENHI-PROJECT-19300109
[Presentation] Roles of the striatonigral neural pathway in basal ganglia circuitry in two-choice reaction time task.2009
- Author(s)
  Fukabori R, Kai N, Kobayashi K, Yasoshima Y, Tsutsui Y, Kobayashi K.
- Organizer
  4th symposium for Molecular and Cellular Cognition Society-Asia
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-19300109
[Presentation] Behavioral roles of the striatonigral neural pathway in reinforcement learning2009
- Author(s)
  Fukabori R, Kai N, Kobayashi K, Yasoshima Y, Tsutsui Y, Kobayashi K.
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-19300109
[Presentation] Roles of two types of dopamine receptor-containing neurons of nucleus accumbens shell in reward-related behavior2008
- Author(s)
  甲斐信行
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19500297
[Presentation] レーザーマイクロダイセクション法を用いた,発生初期マウス胚脊髄に発現する分子の検索2008
- Author(s)
  増田知之, 甲斐信行, 佐久間千恵, 古閑久佐志, 八木沼洋行
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19590191
[Presentation] Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the spinal cord2008
- Author(s)
  増田知之, 佐久間千恵, 甲斐信行, 古閑久佐志, 小林和人, 八木沼洋行
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  兵庫
- Year and Date
  2008-12-10
- Data Source
  KAKENHI-PROJECT-19590191
[Presentation] Conditional ablation of dopamine D2 receptor-containing neurons in the nucleus accumbens shell impairs reward-related behavior2008
- Author(s)
  甲斐信行
- Organizer
  Society for Neuroscience
- Place of Presentation
  Washignton DC
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-19500297
[Presentation] Behavioral and physiological analysis of the striatopallidal neural pathway by conditional transmission silencing.2008
- Author(s)
  Kobayashi K, Kobayashi T, Kai N, Kobayashi K, Fujiwara T, Akagawa K, Onda M, Pastan I.
- Organizer
  38th Annual Meeting of Society for Neuroscience
- Place of Presentation
  Washington DC
- Data Source
  KAKENHI-PROJECT-19300109
[Presentation] Conditional ablation of striatal neuronal types containing dopamine D1 receptors by using immunotoxin cell targeting.2007
- Author(s)
  Kobayashi K, Kai N, Yasoshima Y, Fukabori R
- Organizer
  Dopamine 50 Years
- Place of Presentation
  Gotenborg
- Data Source
  KAKENHI-PROJECT-19300109
[Presentation] Conditional ablation of dopamine D2 receptor-containing neurons in the nucleus accumbens shell impairs reward-related behavior2007
- Author(s)
  甲斐信行
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19500297

1. KOBAYASHI Kenta (70315662)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
2. MASUDA Tomoyuki (70372828)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. KOBAYASHI Kazuto (90211903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. YASOSHIMA Yasunobu (00273566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Kai Nobuyuki 甲斐 信行

KAI Nobuyuki 甲斐 信行

Research Projects

Research Products

Co-Researchers

快情動を伴ったエピソード記憶の維持・強化メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of Social Motivation Formation via the Sense of SmellPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

An analysis of the neural basis of risky choice in the rat gambling task.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of the nucleus accumbens core on development of matching behaviorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of novel genes expressed in the embryonic spinal cord with reference to the sensory axonal guidance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neural circuit mechanisms of behavioral control through striatal projection pathways

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of neural circuits in reward-related behaviorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of novel axonal guidance cues in the mouse embryo

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Functional circuitry analysis in rodents using neurotoxins/ immuno- toxins. In Neuromethods, Controlled Genetic Manipulations chapter 102012

Author(s)

Publisher

Data Source

[Journal Article] Induction of aberrant agonistic behavior by a combination of serotonergic and dopaminergic manipulation in rats2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lesions of the nucleus accumbens core modulate development of matching behavior2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lesions of the nucleus accumbens core modulate development of matching behavior2014

Author(s)

Journal Title

Data Source

[Journal Article] Rho/Rho-kinase signaling pathway controls axon patterning of a specified subset of cranial motor neurons.2011

Author(s)

Journal Title

Data Source

[Journal Article] Lever pressing responses under a fixed-ratio schedule of mice with 6-hydroxydopamine-induced dopamine depletion in the nucleus accumbens2011

Author(s)

Journal Title

Data Source

[Journal Article] Lever pressing responses under a fixed-ratio schedule of mice with 6-hydroxydopamine -induced dopamine depletion in the nucleus accumbens2011

Kai Nobuyuki 甲斐信行

KAI Nobuyuki 甲斐信行