YAO Jian 姚建

Researcher Number	50303128
Other IDs
Affiliation (Current)	2025: 山梨大学, 大学院総合研究部, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2022: 山梨大学, 大学院総合研究部, 准教授 2014 – 2016: 山梨大学, 総合研究部, 准教授 2009 – 2013: 山梨大学, 医学工学総合研究部, 准教授 2007 – 2012: University of Yamanashi, Interdisciplinary Graduate School of Medicine and Engineering, Associate Professor 2007: 山梨大学, 医学工学総合研究部, 准教授 … More 2006: 山梨大学, 医学工学総合研究部, 助教授 2006: 山梨大学, 大学院医学工学総合研究部, 助教授 2003 – 2005: 山梨大学, 大学院・医学工学総合研究部, 助教授 2003: 山梨大学, 医学工学総合研究部, 助教授 2002: 新潟大学, 大学院・医歯学総合研究科, 助手 1999 – 2001: 新潟大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Kidney internal medicine / Basic Section 53040:Nephrology-related / Urology Except Principal Investigator Kidney internal medicine / Dermatology / Urology / Kidney internal medicine
Keywords	Principal Investigator ギャップ結合 / 酸化ストレス / 腎臓 / connexin43 / gap結合 / メサンギウム細胞 / Connexin43 / 糸球体 / TXNIP / ヘミチャネル … More / コネキシン43 / コネクシン / シグナル伝達 / 細胞死 / コネクシン43 / ATP / 傍糸球体装置 / レニン / 内皮細胞 / B 細胞 / 抗体 / 抗体産生細胞 / プリスタン / 腎機能 / ループス腎炎 / 抗体産生 / B細胞 / パネキシン / 免疫染色 / シクロホスファミド / チャネル / NADPH oxidase / inflammasome / 間質膀胱炎 / Cx43 / 相互作用 / インフラマソーム活性化 / 間質性膀胱炎 / 膀胱 / TRPV4 / Calcium / Protein kinase A / Phosphodiesterase 3 / Nitric oxide / Endothelial cells / Gap junction / Mesangial cells / protein kinaseA / 内比細胞 / protein kinase A / PDGF / nitric oxide / ギャプ結合 / 上皮細胞 / 細胞間接着 / コネキシン４３ / P38 / 細胞傷害 / 足細胞 / 炎症 / AMPK / 虚血 / 病理学 / 腎臟 / cAMP / 細胞間コミュニケーション / レニン分泌細胞 / 生理学 / コネキシン / 細胞毒性 / 尿細管上皮細胞 / 抗生物質 / 薬理学 / 尿細管細胞 / aminoglycosides / 小胞体ストレス / Ca波 / 単離腎かん流 / カルシウムウェーブ / 単離糸球体 / NO / connexin 43 / 蛋白フォスファターゼ / 蛋白キナーゼ … More Except Principal Investigator ギャップ結合 / メサンギウム細胞 / 糸球体硬化 / NF-kB / NF-κB / 糸球体腎炎 / 炎症 / シグナル伝達 / 小胞体ストレス / 免疫抑制 / 樹状細胞 / signal transduction / endotoxemia / heavy metal toxicity / transeenic mouse / secreted alkaline nhosohatase / endonlasmic reticulum stres / inflammation / biosensor / 分泌方アルカリフォスファターゼ / 細胞移植 / 分泌型アルカリフォスファター / 遺伝子治療 / 遺伝子導入 / 病理 / シゲナル伝達 / 重金属 / 急性腎不全 / 敗血症 / 重金属中毒 / トランスジェニックマウス / 分泌型アルカリフォスファターゼ / バイオセンサー / disturbance of functional regulation / hemodynamic analysis / experimental animals / glomerulosclerosis / gap junction / syncytium / mesangial cells / renal glomeruli / 実験動物モデル / 機能制御破綻 / 微小循環動態解析 / 実験動物 / 合胞体 / 腎糸球体 / Confocal Laser scanning microscopy / CD 31 / Glomerular hemodynamics / Vascular Endothelial Growth Factor / glomerular endothelial cells / Anti-Thy-1 antibody / Glomerulosderosis / Vascular regeneration / CD106 / CD54 / 抗Thy-1抗体 / 共焦点レーザー顕微鏡 / CD31(PECAM-1) / 糸球体血行動態 / VEGF / 糸球体内皮細胞 / 抗Thy1抗体 / 血管再生 / connexin43 / cyclophosphamide / コネキシン43 / チャネル / 間質性膀胱炎 / 膀胱炎 / 膀胱上皮細胞 / 機械的刺激 / 酸化ストレス / ヘミチャネル / ATP / 膀胱 / 接触皮膚炎 / 抗炎症剤 / 臨床 / 薬剤反応性 / 生体分子 / 免疫学 / 内科 / サイトカイン / 糸球体上皮細胞 / 尿細管細胞 / 腎臓病学 / 胞体ストレス / 尿細管傷害 / 3'-deoxyadenosine / mTOR / Akt / 細胞死(アポトーシス) / 腎尿細管障害 / ATF6 / IRE1 / 4-phenylbutyric acid / 3’-deoxyadenosine / 細胞死（アポトーシス） / アポトーシス / 腎疾患 / 抗炎症作用 / コネキシン / 内皮細胞 / 血管由来過分極因子 / レニン産生細胞 Less

Role of gap junction protein connexin43 in B cell activation and lupus nephritisPrincipal Investigator
- Principal Investigator
  
  Yao Jian
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  University of Yamanashi
Role of TRPV4/Connexin/Pannexin Interaction in Bladder CystitisPrincipal Investigator
- Principal Investigator
  
  YAO Jian
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Role of gap junction protein connexin43 in podocyte injuryPrincipal Investigator
- Principal Investigator
  
  YAO Jian
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
Role of connexin hemichannels in the bladder outlet obstruction
- Principal Investigator
  
  KAMIYAMA Manabu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Role of gap junction-mediated intercellular communication on schaemia/reperfusion renal injuryPrincipal Investigator
- Principal Investigator
  
  YAO Jian
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
Analysis of regulation of inflammation on the skin : Toward development of platform for new anti-inflammatory drug
- Principal Investigator
  
  MATSUE Hiroyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Chiba University
Roles of ER stress in renal pathophysiology and development of novel therapeutic approaches to kidney diseases
- Principal Investigator
  
  KITAMURA Masanori
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
Role of intercellular communication in the control of renin secretionPrincipal Investigator
- Principal Investigator
  
  YAO Jian
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
免疫・炎症反応におけるギャップ結合の機能の解析及びギャップ結合阻害外用剤の開発
- Principal Investigator
  
  MATSUE Hiroyuki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Chiba University
ギャップ結合を介した細胞間コミュニケーションの炎症性賢障害における役割Principal Investigator
- Principal Investigator
  
  姚建
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
ギャップ結合を介した血管内皮細胞由来弛緩因子による傍糸球体細胞レニン分泌制御機構
- Principal Investigator
  
  田邉信明
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Urology
- Research Institution
  University of Yamanashi
Development of in vivo biosensors using genetic engineering
- Principal Investigator
  
  KITAMURA Masanori
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
Functional analysis of mesangial cell syncytium and elucidation of mechanisms involving progressive glomerulosclerosis
- Principal Investigator
  
  OITE Takashi
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
The mechanisms involved in the regulation of mmesangial cell phenotype by endothetial cells : role of gap junctionPrincipal Investigator
- Principal Investigator
  
  YAO Jian
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Yamanashi
傍系球体装置のシグナル伝達:ギャップ結合・カルシウムウェーブの役割Principal Investigator
- Principal Investigator
  
  姚建
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
Prevention of glomerulosderpsis by vascular regeneration
- Principal Investigator
  
  MORIOKA Tetsuo
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University
糸球体内皮細胞によるメサンギウム細胞機能制御の分子機構:プロテインフォスファターゼの役割Principal Investigator
- Principal Investigator
  
  姚建
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Niigata University

[Book] Annual Review腎臓(Gap Junctionを介した細胞間情報伝達メサンギウム細胞の動態制御に於ける役割)2009
- Author(s)
  姚建、北村正敬
- Data Source
  KAKENHI-PROJECT-20390235
[Book] Chapter in Cell adhesion Molecules in the kidney(Pathophysiological roles of gap junction in kidney)(edited by Ichiei Narita)2009
- Author(s)
  姚建
- Publisher
  published by Koko-do Co.
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Development of Dietary Thiol Antioxidant via Reductive Modification of Whey Protein and Its Application in the Treatment of Ischemic Kidney Injury2023
- Author(s)
  Sui Yang、Jiang Rui、Niimi Manabu、Hong Jingru、Yan Qiaojing、Shi Zhuheng、Yao Jian
- Journal Title
  
  Antioxidants
  
  Volume: 12 Issue: 1 Pages: 193-193
- DOI
  10.3390/antiox12010193
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08606
[Journal Article] The Combined Administration of Vitamin C and Copper Induces a Systemic Oxidative Stress and Kidney Injury2023
- Author(s)
  Jiang Rui、Sui Yang、Hong Jingru、Niimi Manabu、Yan Qiaojing、Shi Zhuheng、Yao Jian
- Journal Title
  
  Biomolecules
  
  Volume: 13 Issue: 1 Pages: 143-143
- DOI
  10.3390/biom13010143
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08606
[Journal Article] Tanshinone IIA stimulates cystathionine γ-lyase expression and protects endothelial cells from oxidative injury2021
- Author(s)
  Qiaojing Yan, Zhimin Mao, Jingru Hong, Kun Gao, Manabu Niimi, Takahiko Mitsui, Jian Yao
- Journal Title
  
  Antioxidants
  
  Volume: 10/7 Issue: 7 Pages: 1007-1007
- DOI
  10.3390/antiox10071007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08606
[Journal Article] Hydrogen sulfide as a potent scavenger of toxicant acrolein.2021
- Author(s)
  Zhimin Mao, Yanru Huang, Bingqian Li, Kazutoshi Tomoya, Hideyuki Shinmori, Xuhui Zeng, Zhifeng Gu, Jian Yao
- Journal Title
  
  Ecotoxicology and Environmental Safety
  
  Volume: 229 Pages: 113111-113111
- DOI
  10.1016/j.ecoenv.2021.113111
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08606, KAKENHI-PROJECT-21K04674
[Journal Article] Reductively modified albumin attenuates DSS-Induced mouse colitis through rebalancing systemic redox state2021
- Author(s)
  Xiawen Yang, Zhimin Mao, Yanru Huang, Haizhao Yan, Qiaojing Yan, Jingru Hong, Jianglin Fan, Jian Yao
- Journal Title
  
  Redox Biol
  
  Volume: 41 Pages: 101881-101881
- DOI
  10.1016/j.redox.2021.101881
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08606
[Journal Article] Connexin Hemichannels Contribute to the Activation of cAMP Signaling Pathway and Renin Production2020
- Author(s)
  Jingru Hong, Jian Yao
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21(12) Issue: 12 Pages: 4462-4462
- DOI
  10.3390/ijms21124462
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08606
[Journal Article] Hydrogen Sulfide Mediates Tumor Cell Resistance to Thioredoxin Inhibitor2020
- Author(s)
  Z. Mao, X. Yang, S. Mizutani, Y. Huang, Z. Zhang, H. Shinmori, K. Gao, J. Yao
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 10 Pages: 252-252
- DOI
  10.3389/fonc.2020.00252
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K04724, KAKENHI-PROJECT-17K11176
[Journal Article] Gap junctions amplify TRPV4 activation-initiated cell injury via modification of intracellular Ca 2+ and Ca 2+-dependent regulation of TXNIP2020
- Author(s)
  Xiling Zhang, Zhimin Mao, Yanru Huang, Zhen Zhang, Jian Yao
- Journal Title
  
  Channels
  
  Volume: 14(1) Issue: 1 Pages: 246-256
- DOI
  10.1080/19336950.2020.1803552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08606
[Journal Article] Connexin43 Is Required for the Effective Activation of Spleen Cells and Immunoglobulin Production2019
- Author(s)
  Huang Yanru、Mao Zhimin、Zhang Xiling、Yang Xiawen、Sawada Norifumi、Takeda Masayuki、Yao Jian
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 22 Pages: 5789-5789
- DOI
  10.3390/ijms20225789
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11176
[Journal Article] Hydrogen sulfide donor NaHS alters antibody structure and function via sulfhydration2019
- Author(s)
  Zhang Zhen、Fang Xin、Yang Xiawen、Mitsui Takahiko、Huang Yanru、Mao Zhimin、Huang Yong、Takeda Masayuki、Yao Jian
- Journal Title
  
  International Immunopharmacology
  
  Volume: 73 Pages: 491-501
- DOI
  10.1016/j.intimp.2019.05.052
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11176
[Journal Article] Pharmacological levels of hydrogen sulfide inhibit oxidative cell injury through regulating the redox state of thioredoxin2019
- Author(s)
  Mao Z, Huang Y, Zhang Z, Yang X, Zhang X, Huang Y, Sawada N, Mitsui T, Takeda M, Yao J
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 11 Pages: 190-199
- DOI
  10.1016/j.freeradbiomed.2019.01.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11176
[Journal Article] Connexin43 Contributes to Inflammasome Activation and Lipopolysaccharide-Initiated Acute Renal Injury via Modulation of Intracellular Oxidative Status2019
- Author(s)
  Huang Yanru、Mao Zhimin、Zhang Zhen、Obata Fumiko、Yang Xiawen、Zhang Xiling、Huang Yong、Mitsui Takahiko、Fan Jianglin、Takeda Masayuki、Yao Jian
- Journal Title
  
  Antioxidants & Redox Signaling
  
  Volume: 31 Issue: 16 Pages: 1194-1212
- DOI
  10.1089/ars.2018.7636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11176
[Journal Article] Induction of inactive TGF-β1 monomer formation by hydrogen sulfide contributes to its suppressive effects on Ang II- and TGF-β1-induced EMT in renal tubular epithelial cells2018
- Author(s)
  Huang Y, Zhang Z, Huang Y, Mao Z, Yang X, Nakamura Y, Sawada N, Mitsui T, Takeda M, Yao J
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 501 Issue: 2 Pages: 534-540
- DOI
  10.1016/j.bbrc.2018.05.032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11176
[Journal Article] The pivotal role of extracellular signal-regulated kinase in gap junction-mediated regulation of TXNIP2017
- Author(s)
  Gao S, Zhang X, Gao K, Zhang Z, Huang Y, Yoda R, Yao J
- Journal Title
  
  Cell Signal
  
  Volume: 38 Pages: 116-126
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11176
[Journal Article] Glutathione inhibits antibody and complement-mediated immunologic cell injury via multiple mechanisms.2017
- Author(s)
  Zhang Z, Zhang X, Fang X, Niimi M, Huang Y, Piao H, Gao S, Fan J, Yao J.
- Journal Title
  
  Redox Biol.
  
  Volume: 12 Pages: 571-581
- DOI
  10.1016/j.redox.2017.03.030
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461219, KAKENHI-PROJECT-17K11176, KAKENHI-PROJECT-15H04718
[Journal Article] Carbenoxolone inhibits TRPV4 channel-initiated oxidative urothelial injury and ameliorates cyclophosphamide-induced bladder dysfunction2017
- Author(s)
  Zhang X,Gao S,Tanaka M,Zhanq Z,Huanq Y,Mitsui T,Kamiyama M,Koizumi S,Fan J,Takeda M,Yao J
- Journal Title
  
  J Cell Mol Med
  
  Volume: 2017 Issue: 9 Pages: 346-346
- DOI
  10.1111/jcmm.13100
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04972, KAKENHI-PROJECT-16H04669, KAKENHI-PROJECT-26461219, KAKENHI-PROJECT-26462438, KAKENHI-PROJECT-17K11176, KAKENHI-PROJECT-15H04718
[Journal Article] Connexin43 hemichannels contributes to the disassembly of cell junctions. through modulation of intracellular oxidative status2016
- Author(s)
  Chi Y, Zhang X, Zhang Z, Mitsui T, Kamiyama M, Takeda M, Yao J.
- Journal Title
  
  Redox Biol.
  
  Volume: 9 Pages: 198-209
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462438
[Journal Article] AMPK Suppresses Connexin43 Expression in the Bladder and Ameliorates Voiding Dysfunction in Cyclophosphamide-induced Mouse Cystitis2016
- Author(s)
  Zhang X, Yao J, Gao K, Chi Y, Mitsui T, Ihara T, Sawada N, Kamiyama M, Fan J, Takeda M
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 19708-19708
- DOI
  10.1038/srep19708
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461219, KAKENHI-PROJECT-26462438, KAKENHI-PROJECT-25670190, KAKENHI-PROJECT-15H04718, KAKENHI-PROJECT-15H04972
[Journal Article] Connexin43 hemichannels contributes to the disassembly of cell junctions. through modulation of intracellular oxidative status2016
- Author(s)
  Chi Y, Zhang X, Zhang Z, Mitsui T, Kamiyama M, Takeda M, Yao J.
- Journal Title
  
  Redox Biol.
  
  Volume: 9 Pages: 198-209
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461219
[Journal Article] Suramin inhibits antibody binding to cell surface antigens and disrupts complement-mediated mesangial cell lysis.2016
- Author(s)
  Piao H, Chi Y, Zhang X, Zhang Z, Gao K, Niimi M, Kamiyama M, Zhang J, Takeda M, Yao J
- Journal Title
  
  J Pharmacy Sci.
  
  Volume: accepted Issue: 4 Pages: 224-234
- DOI
  10.1016/j.jphs.2016.03.011
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461219, KAKENHI-PROJECT-26462438
[Journal Article] p53 protein-mediated up-regulation of MAP kinase phosphatase 3 (MKP-3) contributes to the establishment of the cellular senescent phenotype through dephosphorylation of extracellular signal-regulated kinase 1/2 (ERK1/2)2015
- Author(s)
  Zhang H, Chi Y, Gao K, Zhang X, Yao J.
- Journal Title
  
  J Biol Chem.
  
  Volume: 290(2) Issue: 2 Pages: 1129-1140
- DOI
  10.1074/jbc.m114.590943
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461219
[Journal Article] Upregulation of connexin43 contributes to PX-12-induced oxidative cell death2015
- Author(s)
  Li G, Gao K, Chi Y, Zhang X, Mitsui T, Yao J, Takeda M.
- Journal Title
  
  Tumor Biol.
  
  Volume: 7 Issue: 6 Pages: 7535-7546
- DOI
  10.1007/s13277-015-4620-7
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461219
[Journal Article] A novel TXNIP-based mechanism for Cx43-mediated regulation of oxidative drug injury2015
- Author(s)
  Gao K, Chi Y, Zhang X, Zhang H, Li G, Sun W, Takeda M, Yao J.
- Journal Title
  
  J Cell Mol Med.
  
  Volume: 19 Issue: 10 Pages: 2469-2480
- DOI
  10.1111/jcmm.12641
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461219
[Journal Article] eIF2α-Independent Inhibition of TNF-α-Triggered NF-κB Activation by Salubrinal2015
- Author(s)
  Nakajima S, Chi Y, Gao K, Kono K, Yao J.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 38 Issue: 9 Pages: 1368-1374
- DOI
  10.1248/bpb.b15-00312
- NAID
  130005096975
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461219
[Journal Article] Suppression of cell membrane permeability by suramin: involvement of its inhibitory actions on connexin 43 hemichannels2014
- Author(s)
  Chi Y, Gao K, Zhang H, Takeda M, Yao J.
- Journal Title
  
  Br J Pharmacol
  
  Volume: In press Issue: 14 Pages: 3448-3462
- DOI
  10.1111/bph.12693
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591187, KAKENHI-PROJECT-26461219
[Journal Article] Purinergic control of AMPK activation by ATP released through connexin 43 hemichannels - pivotal roles in hemichannel-mediated cell injury.2014
- Author(s)
  Chi Y, Gao K, Li K, Nakajima S, Kira S, Takeda M, Yao J.
- Journal Title
  
  J Cell Sci
  
  Volume: 127 Pages: 1487-1499
- DOI
  10.1242/jcs.139089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591187
[Journal Article] 5'-AMP-activated protein kinase attenuates adriamycin-induced oxidative podocyte injury through thioredoxin-mediated suppression of the apoptosis signal-regulating kinase 1-P38 signaling pathway2014
- Author(s)
  Gao K, Chi Y, Sun W, Takeda M, Yao J.
- Journal Title
  
  Mol Pharmacol
  
  Volume: 85 Issue: 3 Pages: 460-471
- DOI
  10.1124/mol.113.089458
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591187
[Journal Article] Glomerular expression of connexin 40 and connexin 43 in rat experimental glomerulonephritis2013
- Author(s)
  Morioka T, Okada S, Nameta M, Kamal F, Yanakieva-Georgieva NT, Yao J, Sato A, Piao H and Oite T
- Journal Title
  
  Clin Exp. Nephrol
  
  Volume: Vol.17, No.2 Issue: 2 Pages: 191-204
- DOI
  10.1007/s10157-012-0687-2
- NAID
  10031169466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591187
[Journal Article] Eviprostat activates cAMP signaling pathway and suppresses bladder smooth muscle cell proliferation2013
- Author(s)
  Li K, Yao J, Chi Y, Sawada N, Araki I, Kitamura M, and Takeda M
- Journal Title
  
  Int J Mol Sci
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Eviprostat activates cAMP signaling pathway and suppresses bladder smooth muscle cell proliferation2013
- Author(s)
  Li K, Yao J, Chi Y, Sawada N, Araki I, Kitamura M and Takeda M
- Journal Title
  
  Int J Mol Sci
  
  Volume: Vol.14, No.6 Issue: 6 Pages: 12107-12122
- DOI
  10.3390/ijms140612107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591187, KAKENHI-PROJECT-24592428
[Journal Article] Connexin43 hemichannel-mediated regulation of connexin432013
- Author(s)
  Li K, Chi Y, Gao K, Yan Q, Matsue H, Takeda T, Kitamura M, and Yao J
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 2 Pages: e58057-e58057
- DOI
  10.1371/journal.pone.0058057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23390381, KAKENHI-PROJECT-23591187, KAKENHI-PROJECT-24592426
[Journal Article] NADPH oxidase-mediated upregulation of connexin43 contributes to podocyte injury2012
- Author(s)
  Yan Q, Gao K, Chi Y, Li K, Zhu Y, Wan Y,Sun W,Matsue H, Kitamura M, and Yao Y
- Journal Title
  
  Free Rad Biol Med
  
  Volume: 53 Issue: 6 Pages: 1286-1297
- DOI
  10.1016/j.freeradbiomed.2012.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23591187
[Journal Article] β-catenin signaling contributes to PDGF-elicited bladder smooth muscle cell contraction through up-regulation of Cx43 expression2012
- Author(s)
  Li K, Yao J, Sawada N, Kitamura M, Andersson K-E, and Takeda M
- Journal Title
  
  J Urol
  
  Volume: 188 Issue: 1 Pages: 307-332
- DOI
  10.1016/j.juro.2012.02.2556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23591187, KAKENHI-PROJECT-23659754, KAKENHI-PROJECT-24592426
[Journal Article] Unfolded protein response causes a phenotypic shift of inflamed glomerular cells towards redifferentiation through dual blockade of Akt and Smad signaling pathways2012
- Author(s)
  Johno H, Nakajima S,Kato H,Yao J, Paton AW, Paton JC, Katoh R, Shimizu F, and Kitamura M
- Journal Title
  
  Am J Pathol
  
  Volume: 181 Issue: 6 Pages: 1977-1990
- DOI
  10.1016/j.ajpath.2012.08.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23591187, KAKENHI-PROJECT-24790840
[Journal Article] Cordycepin as a sensitizer to TNF-α- induced apoptosis through eIF2α- and mTORC1- mediated inhibition of NF-κB2012
- Author(s)
  Kadomatsu M, Nakajima S, Kato H, Gu L, Chi Y, Yao J and Kitamura M
- Journal Title
  
  Clin Exp Immunol
  
  Volume: 168 Issue: 3 Pages: 325-332
- DOI
  10.1111/j.1365-2249.2012.04580.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-23591187, KAKENHI-PROJECT-24790840
[Journal Article] Connexin43 hemichannels contribute to cadmium- induced oxidative stress and cell injury2011
- Author(s)
  Fang X, Huang T, ZhuY, Jiang JX, Wang P, Kitamura Mand Yao J
- Journal Title
  
  Antioxid Redox Signal
  
  Volume: 14 Issue: 12 Pages: 2427-2439
- DOI
  10.1089/ars.2010.3150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-21390324
[Journal Article] Induction of CCAAT/enhancer-binding protein-homologous protein by cigarette smoke through the superoxide anion- triggered PERK - eIF2αpathway2011
- Author(s)
  Tagawa Y, Hiramatsu N, Kato H, Sakoh T, Nakajima S, Hayakawa K, Saito Y, Johno H, Takahashi S, Gu L, Yao J, and Kitamura M
- Journal Title
  
  Toxicology
  
  Volume: 287 Issue: 1-3 Pages: 105-112
- DOI
  10.1016/j.tox.2011.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Impairment of MCP-1 expression in mesothelial cells exposed to PDF by osmotic stress and acidic stress2011
- Author(s)
  Ogata R, Hiramatsu N, Hayakawa K, Nakajima S, Yao J, Kobayashi T, and Kitamura M
- Journal Title
  
  Perit Dial Int
  
  Volume: 31 Issue: 1 Pages: 80-89
- DOI
  10.3747/pdi.2009.00159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Reciprocal regulation between proinflammatory cytokine-induced iNOS and connexin43 in bladder smooth muscle cells2011
- Author(s)
  Li K, Yao J, Shi L, Sawada N, Chi Y, Yan Q, Fukayama M, Zakohji H, Araki I, Kitamura Mand Takeda M
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 48 Pages: 41552-41562
- DOI
  10.1074/jbc.m111.274449
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-21390324, KAKENHI-PROJECT-23591187
[Journal Article] Selective abrogation of BiP/GRP78 blunts activation of NF-kB through the ATF6 branch of the UPR : involvement of C/EBP β and mTOR-dependent dephosphorylation of Akt.2011
- Author(s)
  Nakajima S, Hiramatsu N, Hayakawa K, Saito Y, Kato H, Huang T, Yao J, Paton AW, Paton JC, Kitamura M
- Journal Title
  
  Mol Cell Biol 31
  
  Pages: 1710-1718
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Selective abrogation of BiP/GRP78 blunts activation of NF-κB through the ATF6 branch of the UPR: involvement of C/EBPβand mTOR-dependent dephosphorylation of Akt2011
- Author(s)
  Nakajima S, HiramatsuN, Hayakawa K, Saito Y, Kato H, Huang T, Yao J, Paton AW, Paton JC, and Kitamura M
- Journal Title
  
  Mol Cell Biol
  
  Volume: 31 Issue: 8 Pages: 1710-1718
- DOI
  10.1128/mcb.00939-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-22390098
[Journal Article] Impairment of MCP-1 expression in mesothelial cells exposed to PDF by osmotic stress and acidic stress.2011
- Author(s)
  Ogata R, Hiramatsu N, Hayakawa K, Nakajima S, Yao J, Kobayashi T, Kitamura M
- Journal Title
  
  Perit Dial Int 31
  
  Pages: 80-89
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Subtilase cytotoxin activates MAP kinases through PERK and IRE1 branches of the unfolded protein response2011
- Author(s)
  Zhao Y,Tian T, Huang T,Nakajima S, Saito Y, Takahashi S, Yao J, Paton AW, PatonJC, and Kitamura M
- Journal Title
  
  Toxicol Sci
  
  Volume: 120 Issue: 1 Pages: 79-86
- DOI
  10.1093/toxsci/kfq368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Cytoprotective roles of ERK and Akt in endoplasmic reticulum stress triggered by subtilase cytotoxin2011
- Author(s)
  Tian T, Zhao Y, Nakajima S, Huang T, Yao J, Paton AW, Paton JC and Kitamura M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 410 Issue: 4 Pages: 852-858
- DOI
  10.1016/j.bbrc.2011.06.078
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Nonsteroidal anti-inflammatory drug flufenamic acid is a potent activator of AMPK2011
- Author(s)
  Chi Y, Li K, Yan Q, Koizumi S, Shi L, Takahashi S, Zhu Y, Matsue H, Takeda M, Kitamura M, Yao J
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 339 Issue: 1 Pages: 257-266
- DOI
  10.1124/jpet.111.183020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-21390324, KAKENHI-PROJECT-23591187
[Journal Article] Connexin43 hemichannels contribute to cadmium-induced oxidative stress and cell injury.2011
- Author(s)
  Fang X, Huang T, Zhu Y, Jiang JX, Wang P, Kitamura M, Yao J
- Journal Title
  
  Antioxid Redox Signal 15 14
  
  Pages: 2427-2439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Selective abrogation of BiP/GRP78 blunts activation of NF-κB through the ATF6 branch of the UPR : involvement of C/EBPβand mTOR-dependent dephosphorylation of Akt.2011
- Author(s)
  Nakajima S, Hiramatsu N, Hayakawa K, Saito Y, Kato H, Huang T, Yao J Paton AW, Paton JC, Kitamura M
- Journal Title
  
  Mol Cell Biol 31
  
  Pages: 1710-1718
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Selective deletion of adipocytes, but not preadipocytes, by TNF-α via C/EBP- and PPARγ-mediated suppression of NF-κB2010
- Author(s)
  Tamai M, Shimada T, Hiramatsu N, Hayakawa K, Okamura M, Tagawa Y, Takahashi S, Nakajima S, Yao J, and Kitamura M
- Journal Title
  
  Lab Invest
  
  Volume: 90 Issue: 9 Pages: 1385-1395
- DOI
  10.1038/labinvest.2010.118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Disruption of gap junction attenuates aminoglycoside-elicited renal tubular cell injury2010
- Author(s)
  Yao J, et al.
- Journal Title
  
  British Journal of Pharmacology (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] ER stress depresses NF-κB activation in mesangial cells through preferential induction of C/EBPβ2010
- Author(s)
  Hayakawa K, Nakajima S, Hiramatsu N, Okamura M, Huang T, Saito Y, Tagawa Y, Tamai M, Takahashi S, Yao J, and Kitamura M
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 21 Issue: 1 Pages: 73-81
- DOI
  10.1681/asn.2009040432
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Anti-inflammatory subtilase cytotoxin up-regulates A20 through the unfolded protein response2010
- Author(s)
  Nakajima S,Saito Y, Takahashi S, Hiramatsu N, Kato H,Johno H, Yao J, Paton AW, Paton JC, and Kitamura M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 397 Issue: 2 Pages: 176-180
- DOI
  10.1016/j.bbrc.2010.05.069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] ER stress depresses NF-κB activation in mesangial cells through preferential induction of C/EBPβ.2010
- Author(s)
  Hayakawa K, Nakajima S, Hiramatsu N, Okamura M, Huang T, Saito Y, Tagawa Y, Tamai M, Takahashi S, YaoJ, Kitamura M
- Journal Title
  
  J Am Soc Nephrol 21
  
  Pages: 73-81
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Selective deletion of adipocytes, but not preadipocytes, by TNF-α via C/EBP- and PPARγ-mediated suppression of NF-κB.2010
- Author(s)
  Tamai M, Shimada T, Hiramatsu N, Hayakawa K, Okamura M, Tagawa Y, Takahashi S, Nakajima S, Yao J, Kitamura M
- Journal Title
  
  Lab Invest 90
  
  Pages: 1385-1395
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Gap junctions sensitize cancer cells to proteasome inhibitor MG132-induced apoptosis2010
- Author(s)
  Huang T, Zhu Y, Fang X, Chi Y, Kitamura M, and Yao J
- Journal Title
  
  Cancer Sci
  
  Volume: 101 Issue: 3 Pages: 716-721
- DOI
  10.1111/j.1349-7006.2009.01421.x
- NAID
  10026589655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Anti-inflammatory subtilase cytotoxin up-regulates A20 through the unfolded protein response.2010
- Author(s)
  Nakajima S, Saito Y, Takahashi S, Hiramatsu N, Kato H, Johno H, Yao J, Paton AW, Paton JC, Kitamura M
- Journal Title
  
  Biochem Biophys Res Commun 397
  
  Pages: 176-180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Suppression of nephrin expression by TNF-α via interfering with the cAMP - retinoic acid receptor pathway2010
- Author(s)
  Saito Y, Okamura M, Nakajima S, Hayakawa K, Huang T, Yao J, and Kitamura M
- Journal Title
  
  Am J Physiol-Renal
  
  Volume: 298 Issue: 6 Pages: F1436-F1444
- DOI
  10.1152/ajprenal.00512.2009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Disruption of gap junction attenuates aminoglycoside-elicited renal tubular cell injury.2010
- Author(s)
  Yao J, Huang T, Fang X, Chi Y, Zhu Y, Wan Y, Matsue H, Kitamura M
- Journal Title
  
  Br J Pharmacol 160
  
  Pages: 2055-2068
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Gap junctions sensitize cancer cells to proteasome inhibitor MG132-induced apoptosis.2010
- Author(s)
  Huang T, Zhu Y, Fang X, Chi Y, Kitamura M, Yao J
- Journal Title
  
  Cancer Sci 101
  
  Pages: 713-721
- NAID
  10026589655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Disruption of gap junction attenuates aminoglycoside- elicited renal tubular cell injury2010
- Author(s)
  Yao J, Huang T, Fang X, Chi Y, Zhu Y, Wan Y, Matsue H, and Kitamura M
- Journal Title
  
  Br J Pharmacol
  
  Volume: 160 Issue: 8 Pages: 2055-2068
- DOI
  10.1111/j.1476-5381.2010.00860.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-21390324
[Journal Article] Gap junctional intercellular communication in the juxtaglomerular apparatus2009
- Author(s)
  Yao J, et al.
- Journal Title
  
  American Journal of Physiology-Renal 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Suppression of NF-κB by cyclosporine A and tacrolimus (FK506) via induction of the C/EBP family : Implication for unfolded protein response.2009
- Author(s)
  Du S, Hiramatsu N, Hayakawa K, Kasai A, Okamura M, Huang T, Yao J, Takeda M, Araki I, Sawada N, Paton AW, Paton JC, Kitamura M
- Journal Title
  
  J Immunol 182
  
  Pages: 7201-7211
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Activation of the Akt - NF-κB pathway by subtilase cytotoxin through the ATF6 branch of the unfolded protein response2009
- Author(s)
  YamazakiH, Hiramatsu N, Hayakawa K, Tagawa Y, Okamura M, Ogata R, Huang T,Nakajima S, Yao J, Paton AW, Paton JC, andKitamura M
- Journal Title
  
  J Immunol
  
  Volume: 183 Issue: 2 Pages: 1480-1487
- DOI
  10.4049/jimmunol.0900017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Downregulation of gap junction expression and function by endoplasmic reticulum stress.2009
- Author(s)
  Huang T, Wan Y, Zhu Y, Fang X, Hiramatsu N, Hayakawa K, Paton A, Paton J, Kitamura M, Yao J
- Journal Title
  
  J Cell Biochem 107
  
  Pages: 973-983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Disturbances of glomerular hemodynamics : a risk factor determining progression of glomerular diseases?2009
- Author(s)
  Oite T, Yao J.
- Journal Title
  
  Journal of Nephrology 22(2)
  
  Pages: 196-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Acquisition of anergy to proinflammatory cytokines in non-immune cells through endoplasmic reticulum stress response : A mechanism for subsidence of inflammation.2009
- Author(s)
  Hayakawa K, Hiramatsu N, Okamura M, Yamazaki H, Nakajima S, YaoJ, Paton AW, Paton JC, Kitamura M
- Journal Title
  
  J Immunol 182
  
  Pages: 1182-1191
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Dual suppression of adipogenesis by cigarette smoke through activation of the aryl hydrocarbon receptor and induction of endoplasmic reticulum stress2009
- Author(s)
  Shimada T, Hiramatsu N, Hayakawa K, Takahashi S, Kasai A, Tagawa Y, Mukai M, Yao J, Fujii-Kuriyama Y, and Kitamura M
- Journal Title
  
  Am J Physiol-Endocrinol and Metab
  
  Volume: 296 Issue: 4 Pages: E721-E730
- DOI
  10.1152/ajpendo.90829.2008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Disturbances of glomerular hemodynamics : a risk factor determining progression of glomerular diseases?2009
- Author(s)
  Oite T, Yao J
- Journal Title
  
  J Nephro 22(2)
  
  Pages: 196-202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Suppression of NF-κB by cyclosporine A and tacrolimus (FK506) via induction of the C/EBP family: Implication for unfolded protein response2009
- Author(s)
  Du S, Hiramatsu N, Hayakawa K, Kasai A, Okamura M, Huang T, Yao J, Takeda M, Araki I, Sawada N, Paton AW, Paton JC, and KitamuraM
- Journal Title
  
  J Immunol
  
  Volume: 182 Issue: 11 Pages: 7201-7211
- DOI
  10.4049/jimmunol.0801772
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235, KAKENHI-PROJECT-21592068
[Journal Article] Downregulation of gap junction expression and function by endoplasmic reticulum stress2009
- Author(s)
  Huang T, Wan Y, Zhu Y, Fang X, Hiramatsu N, Hayakawa K, Paton A, Paton J, Kitamura M, and Yao J
- Journal Title
  
  J Cell Biochem
  
  Volume: 107 Issue: 5 Pages: 973-983
- DOI
  10.1002/jcb.22202
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Preferential blockade of dioxin-induced activation of the aryl hydrocarbon receptor by Antrodia camphorata2009
- Author(s)
  Mukai M, Hayakawa K, Okamura M, Tagawa Y, Nakajima S, Saito Y, Takahashi S, Yao J, Nishimura D, Sugi M, Matsunaga M, and Kitamura M
- Journal Title
  
  Biol Pharm Bull32
  
  Volume: 32 Pages: 1510-1515
- NAID
  130000117275
- URL
  https://www.jstage.jst.go.jp/article/bpb/32/9/32_9_1510/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Gap junctional intercellular communication in the juxtaglomerular apparatus2009
- Author(s)
  Yao J, Oite T and Kitamura M
- Journal Title
  
  Am J Physiol - Renal
  
  Volume: 296 Issue: 5 Pages: F939-F946
- DOI
  10.1152/ajprenal.90612.2008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Induction of nephrin gene expression by selective cooperation of the retinoic acid receptor and the vitamin D receptor2009
- Author(s)
  Okamura M, Takano Y, Saito Y, Yao J, and Kitamura M
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 24 Issue: 5 Pages: 3006-3012
- DOI
  10.1152/ajprenal.00602.2007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Gap junctional intercellular communication in the juxtaglomerul arapparatus2009
- Author(s)
  Yao J, et al.
- Journal Title
  
  American Journal of Physiology-Renal (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Acquisition of anergy to proinflammatory cytokines in non-immune cells through endoplasmic reticulum stress response: A mechanism for subsidence of inflammation2009
- Author(s)
  Hayakawa K, Hiramatsu N, Okamura M, Yamazaki H, Nakajima S, Yao J, Paton AW, Paton JC, and Kitamura M
- Journal Title
  
  J Immunol
  
  Volume: 182 Pages: 1182-1191
- URL
  http://www.jimmunol.org/content/182/2/1182.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Gap Junction を介した細胞間情報伝達:メサンギウム細胞の動態制御に於ける役割2009
- Author(s)
  姚建、北村正敬
- Journal Title
  
  Annual Review 腎臓
  
  Pages: 14-19
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Gap junctional intercellular communication in the juxtaglomerular apparatus.2009
- Author(s)
  Yao J, Oite T, Kitamura M
- Journal Title
  
  Am J Physiol - Renal 296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Blockade of the aryl hydrocarbon receptor pathway triggered by dioxin, polycyclic aromatic hydrocarbons and cigarette smoke by Phellinus linteus2008
- Author(s)
  Mukai M, Kasai A, Hiramatsu N, Hayakawa K, Okamura M, Tagawa Y, Yao J, Nakamura T, and Kitamura M
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 31 Pages: 1888-1893
- NAID
  110006936328
- URL
  https://www.jstage.jst.go.jp/article/bpb/31/10/31_10_1888/_article
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response2008
- Author(s)
  Yokouchi M, Hiramatsu N, Hayakawa K, Okamura M, Du S, Kasai A, Takano Y, Shitamura A, Shimada T, Yao J, and Kitamura M
- Journal Title
  
  J Biol Chem
  
  Volume: 283 Pages: 4252-4260
- URL
  http://www.jbc.org/content/283/7/4252.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response2008
- Author(s)
  Yokouchi, M., Hiramatsu, N., Hayakawa, K., Okamura, M., Du, S., Kasai, A., Takano, Y., Shitamura, A., Shimada, T., Yao, J., Kitamura, M
- Journal Title
  
  J Biol Chem 283
  
  Pages: 4252-4260
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Blockade of the dioxin pathway by herbal medicine Formula bupleuri minor: Identification of active entities for suppression of AhR activation2008
- Author(s)
  Kasai A, Hiramatsu N, Hayakawa K, Yao J, and Kitamura M
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 31 Pages: 838-846
- NAID
  110006663938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Direct, continuous monitoring of air pollution by transgenic sensor mice responsive to halogenated and polycyclic aromatic hydrocarbons2008
- Author(s)
  Kasai A, Hiramatsu N, Hayakawa K, Yao J, and Kitamura M
- Journal Title
  
  Environ Health Perspect
  
  Volume: 116 Issue: 3 Pages: 349-354
- DOI
  10.1289/ehp.10722
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Involvement of selective reactive oxygen species upstream of proapoptotic branches of unfolded protein response.2008
- Author(s)
  Yokouchi M, Hiramatsu N, Hayakawa K, Okamura M, Du S, Kasai A, Takano Y, Shitamura A, Shimada T, Yao J, Kitamura M
- Journal Title
  
  J Biol Chem 283
  
  Pages: 4252-4260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] 糸球体メサンギウム細胞の細胞特性2008
- Author(s)
  姚建、北村正敬、追手巌
- Journal Title
  
  日本腎臓学会誌 50
  
  Pages: 554-560
- NAID
  10024900768
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Induction of apoptosis by cigarette smoke via ROS-dependent endoplasmic reticulum stress and CCAAT/enhancer-binding protein-homologous protein (CHOP)2008
- Author(s)
  Tagawa Y, Hiramatsu N, Kasai A, Hayakawa K, Okamura M, Yao J, and Kitamura M
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 45 Issue: 1 Pages: 50-59
- DOI
  10.1016/j.freeradbiomed.2008.03.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] 糸球体メサンギウム細胞の細胞特性2008
- Author(s)
  Yao J, et al.
- Journal Title
  
  日本腎臓学会誌 50
  
  Pages: 554-560
- NAID
  10024900768
- Data Source
  KAKENHI-PROJECT-20590953
[Journal Article] Suppression of adipocyte differentiation by Cordyceps militaris through activation of the aryl hydrocarbon receptor.2008
- Author(s)
  Shimada T, Hiramatsu N, Kasai A, Mukai M, Okamura M, Yao J, Huang T, Tamai M, Takahashi S, Nakamura T, and Kitamura M
- Journal Title
  
  Am J Physiol-Endocrinol and Metab
  
  Volume: 295 Issue: 4 Pages: E859-E867
- DOI
  10.1152/ajpendo.90373.2008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] Involvement of hypoxia-triggered endoplasmic reticulum stress in outlet obstruction-induced apoptosis in the urinary bladder2008
- Author(s)
  Sawada N, Yao J, Hiramatsu N, Hayakawa K, Araki I, Takeda M, and Kitamura M
- Journal Title
  
  Lab Invest
  
  Volume: 88 Issue: 5 Pages: 553-563
- DOI
  10.1038/labinvest.2008.21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] 糸球体メサンギウム細胞の細胞特性2008
- Author(s)
  姚建、北村正敬、追手巌
- Journal Title
  
  日本腎臓学会誌
  
  Volume: 50 Pages: 554-560
- NAID
  10024900768
- Data Source
  KAKENHI-PROJECT-20390235
[Journal Article] コネクシン432007
- Author(s)
  姚建、北村正敬
- Journal Title
  
  腎と透析 63
  
  Pages: 522-525
- Data Source
  KAKENHI-PROJECT-17659255
[Journal Article] Atypical,bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response.2007
- Author(s)
  Yokouchi M, Hiramatsu N, Hayakawa K, Kasai A, Takano Y, Yao J, Kitamura M
- Journal Title
  
  Cell Death Differ 14
  
  Pages: 1467-1474
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Atypical, bidirectional regulation of cadmium-induced apoptosis via distinct signaling of unfolded protein response2007
- Author(s)
  Yokouchi, M., Hiramatsu, N., Hayakawa, K., Kasai, A., Takano, Y., Yao, J., Kitamura, M
- Journal Title
  
  Cell Death Differ 14
  
  Pages: 1467-1474
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Pathological roles of gap junction in glomerular mesangial cells2007
- Author(s)
  Jian Yao, et al.
- Journal Title
  
  J Membr Biol (In press)
- Data Source
  KAKENHI-PROJECT-17659255
[Journal Article] Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal : Evidence from transgenic sensor mice2007
- Author(s)
  Hiramatsu, N., Kasai, A., Du, S., Takeda, M., Hayakawa, K., Okamura, M., Yao, J., Kitamura, M
- Journal Title
  
  FEBS Lett 581
  
  Pages: 2055-2059
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Pathophysiological roles of gap junction in glomerular mesangial cells2007
- Author(s)
  Yao J, et. al.
- Journal Title
  
  J Membrane Biol 217
  
  Pages: 123-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17659255
[Journal Article] Irsogladine maleate potentiates the effects of nitric oxide on activation of cAMP signaling pathway and suppression of mesangial cell mitogenesis2007
- Author(s)
  Jian Yao, et al.
- Journal Title
  
  Br J Pharmacol (In press)
- Data Source
  KAKENHI-PROJECT-17659255
[Journal Article] Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal: Evidence from transgenic sensor mice.2007
- Author(s)
  Hiramatsu N, Kasai A, Du S, Takeda M, Hayakawa K, Okamura M, Yao J, Kitamura M
- Journal Title
  
  FEBS Lett 581
  
  Pages: 2055-2059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Synergistic effects of PDGF-BB and cAMP elevating agents on the expression of connexin43 in mesangial cells.2006
- Author(s)
  Jian Yao, et al.
- Journal Title
  
  Am J Physiol 290(5) : F1083-93 290・5
- Data Source
  KAKENHI-PROJECT-17659255
[Journal Article] Real-time detection and continuous monitoring of ER stress in vitro and in vivo by ES-TRAP : Evidence for systemic, transient ER stress during endotoxemia2006
- Author(s)
  Hiramatsu, N., Kasai, A., Hayakawa, K., Yao, J., Kitamura, M
- Journal Title
  
  Nucleic Acids Res 34
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Priming of glomerular mesangial cells by activated macrophages causes blunted responses to proinflammatory stimuli2006
- Author(s)
  Hayakawa, K., Meng, Y., Hiramatsu, N., Kasai, A., Yamauchi, K., Yao, J., Kitamura, M
- Journal Title
  
  J Immunol 176
  
  Pages: 2529-2537
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Synergistic effects of PDGF-BB and cAMP elevating agents on the expression of connexin43 in mesangial cells.2006
- Author(s)
  Jian Yao, et al.
- Journal Title
  
  Am J Physiol In press
- Data Source
  KAKENHI-PROJECT-17659255
[Journal Article] Unexpected cooperation between platelet-derived growth ---2006
- Author(s)
  Yao J, Kitamura M, Oite T, et al.
- Journal Title
  
  American Journal of physiology : Renal Physiology (印刷中)
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] Turbulence of glomerular hemodynamics involved in progressive glomerulosclerosis.2006
- Author(s)
  K.Kawamura, S.Okada, B.Li, M.Suwa, J.Yao, T.Morioka, F.Gejyo, T.Oite
- Journal Title
  
  Kidney International (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] Nitric oxide-mediated regulation of connexin43 expression and gap junctional intercellular communication in mesangial cells.2005
- Author(s)
  Jian Yao, et al.
- Journal Title
  
  J Am Soc Nephrol 16:58-67 16
  
  Pages: 58-67
- Data Source
  KAKENHI-PROJECT-17659255
[Journal Article] Continuous, non-invasive monitoring of local microscopic inflanmation using genetically engineered cell-based biosensor2005
- Author(s)
  Meng, Y., Kasai, A., Hiramatsu, N., Hayakawa, K., Yamauchi, K., Takeda, M., Kawachi, H., Shimizu, F., Yao, J., Kitamura, M
- Journal Title
  
  Lab Invest 85
  
  Pages: 1429-1439
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Nitric oxide-mediated regulation of connexin43 expression and gap junctional intercellular communication in mesangial cells2005
- Author(s)
  Yao J
- Journal Title
  
  J Am Soc Nephrol 16(1)
  
  Pages: 58-67
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Journal Article] Establishment of immortalized human glomerular endothelial cell lines and their application.2005
- Author(s)
  Harada T, Batsford S, Morioka T, Yao J, Arakawa M, et al.
- Journal Title
  
  Nephron Exp Nephrol 99
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Journal Article] Real-time monitoring of mesangial cell - macrophage cross-talk using SEAP in vitro and ex vivo2005
- Author(s)
  Meng, Y., Kasai, A., Hiramatsu, N., Hayakawa, K., Takeda, M., Shimizu, F., Kawachi, H., Yao, J., Kitamura, M
- Journal Title
  
  Kidney Int 68
  
  Pages: 886-893
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Alkaline phosphatase vs. luciferase as secreted reporter molecules in vivo2005
- Author(s)
  Hiramatsu, N., Kasai, A., Meng, Y., Hayakawa, K., Yao, J., Kitamura, M
- Journal Title
  
  Anal Biochem 339
  
  Pages: 249-256
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Journal Article] Nitric oxide-mediated regulation of connexin43 expression and gap junctional intercellular communication in mesangial cells.2005
- Author(s)
  Yao J, Hiramatsu N, Zhu Y, Morioka T, Takeda M, et al.
- Journal Title
  
  J Am Soc Nephrol 16
  
  Pages: 58-67
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Journal Article] Nitric oxide-mediated regulation of connexin 43 ----2005
- Author(s)
  Yao J, Oite T, Kitamura M, et al.
- Journal Title
  
  J American Society of Nephrology 16
  
  Pages: 58-67
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] Bone marrow cells contribute to regeneration of damaged glomerular endothelial cells.2005
- Author(s)
  K.Ikarashi, B.Li, M.Suwa, K.Kawamura, T.Morioka, J.Yao, F.Khan, M.Uchiyama, T.Oite
- Journal Title
  
  Kidney International 67
  
  Pages: 1925-1933
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] Fast-track DRESSA : a bioassay for fast, sensitive, and selective detection of halogenated and polycyclic aromatic hydrocarbons.2005
- Author(s)
  Kasai A, Hiramatsu N, Meng Y, Yao J, Maeda S, et al.
- Journal Title
  
  Anal Biochem 337
  
  Pages: 84-88
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Journal Article] The characterization of a specific Thy-1 molecular ----2004
- Author(s)
  Morioka T, Yao J, Oite T, et al.
- Journal Title
  
  Kidney International 66
  
  Pages: 2214-2223
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] Real-time observation of glomerular hemodynamic changes in diabetic rats : effects of insulin and ARB.2004
- Author(s)
  Li B, Yao J, Kawamura K, Oyanagi-Tanaka Y, Hoshiyama M, et al.
- Journal Title
  
  Kidney Int 66
  
  Pages: 1939-1948
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Journal Article] AP-1-independent sensitization to oxidative stress-induced apoptosis by proteasome inhibitors.2004
- Author(s)
  Hiramatsu N, Kasai A, Yao J, Meng Y, Takeda M, et al.
- Journal Title
  
  Biochem Biophys Res Commun 316
  
  Pages: 545-552
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Journal Article] DRESSA : biosensing of dioxin and dioxin-like chemicals using secreted alkaline phosphatase.2004
- Author(s)
  Kasai A, Hiramatsu N, Meng Y, Yao J, Takeda M, et al.
- Journal Title
  
  Anal Biochem 335
  
  Pages: 73-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Journal Article] The characterization of a specific Thy-1 molecular epitope expressed on rat mesangial cells.2004
- Author(s)
  Morioka, J.Yao, Y.Suzuki, T.Oite
- Journal Title
  
  Kidney International 66
  
  Pages: 2214-2223
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] Real-time observation of glomerular hemodyamic changes in diabetic rats : effects of insulin and ARB2004
- Author(s)
  Li B, Oite T, Yao J, et al.
- Journal Title
  
  Kidney International 66
  
  Pages: 1939-1948
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] The characterization of a specific Thy-1 molecular epitope expressed on rat mesangial cells.2004
- Author(s)
  Morioka T, Yao J, Suzuki Y, Oite T
- Journal Title
  
  Kidney Int 66
  
  Pages: 2214-2223
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Journal Article] The characterization of a specific Thy-1 molecular epitope expressed on rat mesangial cells2004
- Author(s)
  Morioka T, Oite T, Yao J, et al.
- Journal Title
  
  Kidney International 66
  
  Pages: 2214-2223
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] ATP-dependent mechanisms for coordination of intercellular Ca2+ signaling and renin secretion in rat juxtaglomerular cells.2003
- Author(s)
  J.Yao, M.Suwa, B.Li, K.Kawamura, T.Morioka, T.Oite
- Journal Title
  
  Circulation Research 93
  
  Pages: 338-345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] Disturbance of syncytial cell function in glomerular mesangial cells involved in the progressive glomerular diseases.2003
- Author(s)
  T.Oite, J.Yao, T.Morioka
- Journal Title
  
  Contribution Nephrology 139
  
  Pages: 12-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] ATP-dependent mechanism for coordination of intercellular Ca2+ signaling and renin secretion in rat juxtaglomerular cells.2003
- Author(s)
  Yao J, Suwa M, Li B, Kawamura K, Morioka T, et al.
- Journal Title
  
  Circ Res 93
  
  Pages: 338-345
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Journal Article] Disturbance of syncytial cell function in -----2003
- Author(s)
  Oite T, Yao J, Morioka T.
- Journal Title
  
  Contribution Nephrology 139
  
  Pages: 12-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] ATP-dependent mechanisms for coordination of -----2003
- Author(s)
  Yao J, Suwa M, Oite T, et al.
- Journal Title
  
  Circulation Research 93
  
  Pages: 338-345
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390266
[Journal Article] Effect of high glucose on nitric oxide production and endothelial nitric oxide synthase protein expression in human glomerular endothelial cells.2003
- Author(s)
  Hoshiyama M, Li B, Yao J, Harada T, Morioka T, et al.
- Journal Title
  
  Nephron Exp Nephrol 95
  
  Pages: 62-68
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Journal Article] ATP-dependent mechanism for coordination of intercellular Ca2+ signaling and renin secretion in rat juxtaglomerular cells2003
- Author(s)
  Yao J
- Journal Title
  
  Circulation Research 93(4)
  
  Pages: 338-345
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Journal Article] Disturbance of syncytial cell function in glomerular mesangial cells involved in the progressive glomerular diseases.2003
- Author(s)
  Oite T, Yao J, Morioka T
- Journal Title
  
  Contrib Nephrol 139
  
  Pages: 12-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590845
[Presentation] Connexin43 regulates inflammasome activation and inflammatory cell injury through modulation of NADPH Oxidase-dependent redox signaling pathway2019
- Author(s)
  Yanru Huang and Jian Yao
- Organizer
  International Gap Junction Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11176
[Presentation] Hydrogen sulfide inhibits adramycin-initiated glomerular pococyte injury via interference of Trx/ASK1/P38 signaling2019
- Author(s)
  Jian Yao
- Organizer
  ISN world conference of nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11176
[Presentation] Hydrogen Sulfide Determines Tumor Cell Sensitivity to Thioredoxin Inhibitor PX-122019
- Author(s)
  Zhimin Mao and Jian Yao
- Organizer
  SfRBM2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11176
[Presentation] Role of Gap junctions in inflammasome activation and inflammatory renal diseases2019
- Author(s)
  Jian Yao
- Organizer
  第1回中国大連医科大学免疫及び代謝性疾患研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K11176
[Presentation] Hydrogen sulfide counteracts angiotensin II-stimulated glomerular mesangial proliferation and matrix production via multiple mechanisms2018
- Author(s)
  Zhen Zhang, Jian Yao
- Organizer
  25th annual conference of SFRBM (society for free radical and biological medicine)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11176
[Presentation] Connexin43 regulates inflammasome activation and LPS-initiated acute renal injury via modulation of cellular oxidative status2018
- Author(s)
  Yanru Huang, Jian Yao
- Organizer
  25th annual conference of SFRBM (society for free radical and biological medicine)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11176
[Presentation] Hydrogen sulfide protects cells against oxidative stress through modifying the redox status of thioredoxin2018
- Author(s)
  Zhimin Mao, Jian Yao
- Organizer
  25th annual conference of SFRBM (society for free radical and biological medicine)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11176
[Presentation] Gap junction-mediated regulation of redox signaling and oxidative cellular responses2017
- Author(s)
  Yao Jian
- Organizer
  第40回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-17K11176
[Presentation] Hydrogen sulfide inhibits antibody- and complement-mediated immune responses via S-sulfhydration2017
- Author(s)
  Zhen Zhang, Xiawen Yang, and Jian Yao
- Organizer
  24th Annual Meeting of Free Radical Biology & Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11176
[Presentation] Glutathione inhibits antibody-initiated and complement-dependent lysis of　glomerular mesangial cells via multiple mechanisms2017
- Author(s)
  Zhen Zhang, Jian Yao
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K11176
[Presentation] The pivotal role of TRPV4 and Connexin43 channel transactivation in mediation of aminoglycoside-elicited renal tubular cell injury2017
- Author(s)
  Xiling Zhang, Jian Yao
- Organizer
  第60回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-17K11176
[Presentation] Pannexin channels contribute to air exposure-elicited oxidative injury in bronchial epithelial cells.2016
- Author(s)
  Yanru Huang, Xiling Zhang, Zhen Zhang, Shan Gao, Xin Fang, Jian Yao.
- Organizer
  第39会日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (神奈川県・横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26461219
[Presentation] Pannexin channels contribute to air exposure-elicited oxidative injury in bronchial epithelial cells.2016
- Author(s)
  Yanru Huang, Xiling Zhang, Zhen Zhang, Shan Gao, Xin Fang, Jian Yao.
- Organizer
  第39会日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26462438
[Presentation] Connexin43 channel contributes to TRPV4 activation-elicited oxidative cell injury.2016
- Author(s)
  Xiling Zhang, Manabu Kamiyama, Zhen Zhang, Yanru Huang, Shan Gao, Xin Fang, Masayuki Takeda, Jian Yao.
- Organizer
  第39会日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (神奈川県・横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26461219
[Presentation] Connexin43 channel contributes to TRPV4 activation-elicited oxidative cell injury.2016
- Author(s)
  Xiling Zhang, Manabu Kamiyama, Zhen Zhang, Yanru Huang, Shan Gao, Xin Fang, Masayuki Takeda, Jian Yao.
- Organizer
  第39会日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26462438
[Presentation] MP-activated Protein Kinase Suppresses Connexin43 in Bladder Smooth Muscle Cells and Ameliorates Voiding Dysfunction in Cyclophosphamide-induced Mouse Cystitis2015
- Author(s)
  zhang X, Yao J, Ihara T, Sawada N, Mitsui T, Takeda M
- Organizer
  ICS2015 (International Continence society)
- Place of Presentation
  Conventional Center (Montreal, Canada)
- Year and Date
  2015-10-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461219
[Presentation] Pathophysiological Roles of Gap Junction-Mediated Intercellular Communication in Kidney2015
- Author(s)
  姚建
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26461219
[Presentation] Connexin43 hemichannels contribute to air exposure-elicited oxidative cell injury2015
- Author(s)
  Ryuichi Yoda, Yuan Chi, Xiling Zhang, Zhen Zhang, Tatsuya Yoshitomi and Jian Yao
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26461219
[Presentation] TXNIP Contributes to Gap Junction-Mediated Regulation of Glucose Transporter-1 Expression and Oxidative Cell Injury2015
- Author(s)
  Shan Gao, Xiling Zhang, Yuan Chi, Zhen Zhang, Ryuichi Yoda and Jian Yao
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場(兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26461219
[Presentation] Purinergic control of AMPK activation by ATP released through connexin43 hemichannels : pivotal roles in hemichannel-mediated disassembly of tight junction and cell injury2013
- Author(s)
  Yao J
- Organizer
  International Gap Junction Conference
- Place of Presentation
  Charleston, South Carolina
- Year and Date
  2013-07-15
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Activation of AMPK Protects podocytes from Adriamycin-elicited Injury2013
- Author(s)
  Gao K, Sun W, Chi Y, Kitamura M, and Yao J
- Organizer
  International Society of Nephrology (ISN) World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Connexin43 hemichannel-mediated release of ATP suppresses AMPK activation in renal tubular epithelial cells2012
- Author(s)
  Chi Y, Gao K, Kato H, Nakajima S, Kitamura M, and Yao J
- Organizer
  45^<th> Annual Meeting of American Society of Nephrology
- Place of Presentation
  San Diego
- Year and Date
  2012-11-02
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] beta-catenin signaling contributes to PDGF-elicited bladder smooth muscle cell contraction through upregulation of Cx43 expression2012
- Author(s)
  Li K, Yao J, Sawada N, Miyamoto T, Kitamura M, Takeda M
- Organizer
  2012 Annual Meeting of American Urology Association
- Place of Presentation
  Atlanta
- Year and Date
  2012-05-19
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Suppression of inflammatory cytokines-triggered NFB activation and iNOS expression in renal tubular cells by gap junction inhibitor flufenamic acid : a critical involvement of AMPK2011
- Author(s)
  Chi Y, Yan QJ, Zhu Y, Kitamura M, and Yao J
- Organizer
  44th Annual Meeting of The American Society of Nephrology
- Place of Presentation
  Pennsylvania, Philadelphia
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Roles of gap junctional intercellular communication in renal cell injury2011
- Author(s)
  Yao J
- Organizer
  国際中西医結合腎臓病学術大会
- Place of Presentation
  中国北京
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Dysfunction of gap junctions stimulates COX-2 expression in juxtaglomerular renin-secreting cells2011
- Author(s)
  Yao J, Zhu Y, and Kitamura M
- Organizer
  44th Annual Meeting of The American Society of Nephrology
- Place of Presentation
  Pennsylvania, Philadelphia
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Connexin43 contributes to puromycin-elicited podocyte injury2011
- Author(s)
  Yan QJ Chi Y, Zhu Y, Kitamura M, and Yao J
- Organizer
  44th Annual Meeting of The American Society of Nephrology
- Place of Presentation
  Pennsylvania, Philadelphia
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] NF-κB/iNOS/cAMP signaling cascade mediates inflammatory cytokines-induced upregulation of connexin43 expression and function in urinary tract infection2011
- Author(s)
  Li K, Yao J, Sawada N, Nakagomi H, Miyamoto T, Kira S, Kobayashi H, Tsuchida T, Kitamura M and Takeda M
- Organizer
  The 2011 American Urological Association Annual Meeting
- Place of Presentation
  Washington, D.C.
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Connexin hemichannels mediate low calcium-elicited activation of cAMP signaling pathway and elevation of renin production in juxtaglomerular cells.2010
- Author(s)
  Huang T, Nakajima S, Kitamura M, Yao J
- Organizer
  43rd Annual Meeting of the American Society of Nephrology.
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Connexin43 hemichannels exaggerate cadmium-induced oxidative stress and cell injury in renal tubular epithelial cells.2010
- Author(s)
  Yao J Sun W, Huang T, Nakajima S, Kitamura M
- Organizer
  43rd Annual Meeting of the American Society of Nephrology.
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Participation of gap junction hemichannel in low calcium-elicied renin synthesis and secretion.2010
- Author(s)
  Huang T, Chi Y, Fan X, Zhu Y, Kitamura M, Yao J
- Organizer
  第53回日本腎臓学会総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Anti-inflammatory potential of subtilase cytotoxin : Dual suppression of NF-κB via induction of C/EBPβand mTOR-mediated dephosphorylation of Akt.2010
- Author(s)
  Nakajima S, Huang T, Yao J, Kitamura M
- Organizer
  43rd Annual Meeting of The American Society of Nephrology.
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] Connexin43 hemichannels exaggerate cadmium-induced oxidative stress and cell injury in renal tubular epithelial cells2010
- Author(s)
  Yao J, et al.
- Organizer
  43rd Annual Meeting of The American Society of Nephrology
- Place of Presentation
  Denver. U.S.
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Endoplasmic reticulum stress regulates gap junction expression and function in glomerular mesangial cells.2009
- Author(s)
  Huang T, Zhu Y, Wan Y, Hiramatsu N, Paton AW, Paton JC, Kitamura M, Yao J
- Organizer
  第52回日本腎臓学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] 腎臓におけるギャップ結合を介した細胞間コミュニケーションの役割2009
- Author(s)
  姚建
- Organizer
  第24回新潟腎シンポジウム
- Place of Presentation
  新潟
- Year and Date
  2009-07-25
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Subtilase cytotoxin suppresses TNF-α-induced activation of NF-κB via induction of C/EBPβand suppression of Akt.2009
- Author(s)
  Nakajima S, Hiramatsu N, Hayakawa K, Saito Y, Huang T, Yao J, Kitamura M
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-08
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] 腎臓におけるギャップ結合を介した細胞間コミュニケーションの役割2009
- Author(s)
  Yao J
- Organizer
  新潟腎シンポジウム
- Place of Presentation
  新潟
- Year and Date
  2009-07-28
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Gap junction renders renal tubular cells vulnerable to cadmium-induced injury.2009
- Author(s)
  Fang X, Huang T, Zhu Y, Kitamura M, Yao J
- Organizer
  第52回日本腎臓学会総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Pathophysiological roles of gap junction in renal microcirculation2008
- Author(s)
  姚建
- Organizer
  中国中西医結合微小循環学術大会2008
- Place of Presentation
  中国北京-北京大学
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Suppression of NF-κB by cyclosporine A and tacroLimus (FK506) via induction of the C/EBP family : Implication for unfold protein response response.2008
- Author(s)
  Hayakawa K, Du S, Hiramatsu N, Kasai A, Okamura M, Huang T,Yao J, Sawada N, Takeda M, Kitamura M
- Organizer
  第31回日本分子生物学会年会/第82回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] Gap junction renders renal tubular cell vulnerable to aminoglycosides-induced cytotoxicity.2008
- Author(s)
  Yao J, Huang T, Hiramatsu N, Kitamura M
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Suppression of NF-icB by cyclosporine A and tacrolimus(FK506)via inducrion of the GEB family : Implication for unfolded protein response.2008
- Author(s)
  Kitamura M, Du S, Hiramatsu N, Hayakawa K, Okamura M, Huang T, Yao J, Takeda M
- Organizer
  41st Annual Meeting of The American Society of Nephrology.
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] Participation of gap junction in proteasome inhibition-induced cell damage.2008
- Author(s)
  Huang T, Kitamura M, Yao J
- Organizer
  第31回日本分子生物学会年会/第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Gap junction in renal microcirculation.2008
- Author(s)
  姚建
- Organizer
  中国中西医結合微小循環学術大会2008、(特別報告)北京大学
- Place of Presentation
  北京
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20590953
[Presentation] Direct, continuous monitoring of air pollution by transgenic sensor mice responsive to halogenated and polycyclic aromatic hydrccarbons.2008
- Author(s)
  Kitanmra M, Kasai A, Hiramatsu N, Hayakawa K, Yao J
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20390235
[Presentation] Gap junction propagates and amplifies aminoglycosides-induced cell death in renal tubular epithelial cells2007
- Author(s)
  Yao J, et. al.
- Organizer
  第30回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-17659255
[Presentation] Rapid,transient induction of ER stress in the liver and kidney after acute exposure to heavy metal: Evidence from transgenic sensor mice.2007
- Author(s)
  Kasai A, Hiramatsu N, Du S, Takeda M, Hayakawa K, Okamura M, Yao J, Kitamura M
- Organizer
  BMB2007
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-16390243
[Presentation] Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal : Evidence from transgenic sensor mice2007
- Author(s)
  Kasai, A., Hiramatsu, N., Du, S., Takeda, M., Hayakawa, K., Okamura, M., Yao, J., Kitamura, M
- Organizer
  BMB 2007
- Place of Presentation
  Yokohama, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Presentation] Real-time detection and continuous monitoring of ER stress in vitro and in vivo by ES-TRAP : Evidence for systemic, transient ER stress during endotoxemia2006
- Author(s)
  Hiramatsu, N., Kasai, A., Hayakawa, K., Yao, J., Kitamura, M
- Organizer
  39th Annual Meeting of Am Soc Nephrol
- Place of Presentation
  San Diego
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Presentation] Cadmium-induced apoptosis of renal tubular cells via endoplasmic reticulum stress : Involvement of selective unfolded protein responses2006
- Author(s)
  Yokouchi, M., Hiramatsu, N., Hayakawa, K., Kasai, A., Takano, Y., Yao, J., Kitamura, M
- Organizer
  39th Annual Meeting of Am Soc Nephrol
- Place of Presentation
  San Diego
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390243
[Presentation] P53-mediated upregulation of MKP-3 contributes to the maintenance of cellular senescent phenotype through dephosphorylation of ERK1/2
- Author(s)
  Zhang H, Chi Y, Gao K, Yoda R, Yao J.
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26461219
[Presentation] Dysfunction of gap junctions stimulates COX-2 expression in juxtaglomerular renin-secreting cells
- Author(s)
  Yao J, et al.
- Organizer
  44th Annual Meeting of The American Society of Nephrology
- Place of Presentation
  Pennsylvania convention center (Philadelphia)
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Regulation of Tight Junction and Adherent Junction Disassembly by Connexin43 Hemichannels
- Author(s)
  Yao J, Chi Y, Gao K, Zhang XL, Yoda R.
- Organizer
  2015 Experimental Biology
- Place of Presentation
  Boston Convention & Exhibition Center 「ボストン（アメリカ)」
- Year and Date
  2015-03-28 – 2015-04-01
- Data Source
  KAKENHI-PROJECT-26461219
[Presentation] Purinergic control of AMPK activation by ATP released through connexin43 hemichannels: pivotal roles in hemichannel-mediated disassembly of tight junction and cell injury
- Author(s)
  Yao J, Chi Y, Gao K.
- Organizer
  2013 International Gap Junction Conference
- Place of Presentation
  IGJC (Charleston, South Carolina, USA)
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Regulation of tight junction disassembly by gap junction hemichannels
- Author(s)
  Chi Y, Zhang H, Gao K, Yao J.
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (神奈川県横浜市）
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26461219
[Presentation] 腎細胞傷害に於けるギャップ結合を介した細胞間コミュニケーションの役割
- Author(s)
  Yao J
- Organizer
  ２０１１年国際中西医結合腎臓病学学術会議(招待講演)
- Place of Presentation
  北京国際会議センター（北京）
- Data Source
  KAKENHI-PROJECT-23591187
[Presentation] Activation of AMPK Protects podocytes from Adriamycin-elicited Injury
- Author(s)
  Gao K, Sun W, Chi Y, Yao J.
- Organizer
  World Congress of Nephrology 2013
- Place of Presentation
  Hong Kong Convention and Exhibition Centre (Wan Chai, Hong Kong)
- Data Source
  KAKENHI-PROJECT-23591187

1. KITAMURA Masanori (90333062)

# of Collaborated Projects: 7 results

# of Collaborated Products: 87 results
2. TAKEDA Masayuki (80197318)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. KAMBE Naotomo (50335254)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. MORIOKA Tetsuo (00210146)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
5. OITE Takashi (60018744)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
6. MATSUE Hiroyuki (10250424)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KAMADA Noriaki (00334186)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KAMIYAMA Manabu (90362061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. SAWADA Norifumi (70402055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HANEDA Yaburu (20402068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 田邉信明 (20163602)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 荒木勇雄 (50252424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 柴垣直孝 (40262662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 原田和俊 (20324197)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 新森英之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 小泉修一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YAO Jian 姚 建

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Role of gap junction protein connexin43 in B cell activation and lupus nephritisPrincipal Investigator

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Role of TRPV4/Connexin/Pannexin Interaction in Bladder CystitisPrincipal Investigator

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Role of gap junction protein connexin43 in podocyte injuryPrincipal Investigator

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Role of gap junction-mediated intercellular communication on schaemia/reperfusion renal injuryPrincipal Investigator

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Role of intercellular communication in the control of renin secretionPrincipal Investigator

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ギャップ結合を介した細胞間コミュニケーションの炎症性賢障害における役割Principal Investigator

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The mechanisms involved in the regulation of mmesangial cell phenotype by endothetial cells : role of gap junctionPrincipal Investigator

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YAO Jian 姚建