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Yamada Takeshi  山田 岳史

ORCIDConnect your ORCID iD *help
Researcher Number 50307948
Other IDs
Affiliation (Current) 2025: 日本医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2016 – 2024: 日本医科大学, 医学部, 准教授
2014 – 2015: 日本医科大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Digestive surgery / Basic Section 55020:Digestive surgery-related
Except Principal Investigator
Basic Section 55020:Digestive surgery-related / Digestive surgery / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 51030:Pathophysiologic neuroscience-related / Basic Section 47040:Pharmacology-related
Keywords
Principal Investigator
Liquid biopsy / 抗EGFR抗体 / 大腸癌 / 薬剤耐性 / KRAS / 循環DNA / liquid biopsy / 不均一性 / リキッドバイオプシー / 時間的不均一性 … More / 空間的不均一性 / 細胞外小胞 / Emerging mutation / 分子標的 / EGFR / BRAF / RAS / 循環腫瘍細胞 / 2次耐性 / cell free DNA / circulating DNA / circulating tumor DNA / Circulating tumor DNA / Circulating DNA … More
Except Principal Investigator
liquid biopsy / リキッドバイオプシー / ctDNA / 大腸癌 / バイオマーカー / 循環腫瘍DNA / 細胞外小胞 / 門脈血行動態 / 脾臓 / KRAS / ccfDNA / 外科 / 直腸癌 / 大腸癌肝転移 / 尿中エクソソーム / Liquid biopsy / 微小転移 / cell-free tumor DNA / 局所再発直腸癌 / 局所高度進行直腸癌 / 血中細胞外小胞 / 消化器手術 / 術後感染症 / 大腸ステント / 手術侵襲 / 消化器癌 / 循環DNA / メチル化定量 / 予後 / 胃癌 / 循環DNA量 / 微小残存病変 / LINE-1遺伝子 / 尿中循環腫瘍細胞 / 尿中ctDNA / KRAS遺伝子変異 / 尿中循環腫瘍DNA / 尿循環腫瘍DNA / circRNA / 細胞外RNA / microRNA / オキサリプラチン / lncRNA / 一次感覚神経 / マイクロRNA / 神経障害性疼痛 / 血中腫瘍細胞 / 門脈 / 化学放射線療法 / BRAF / 遺伝子変異 / 骨格筋萎縮 / miRNA / 筋萎縮 / 副作用 / シスプラチン / liqiud biopsy / 循環DNA / ccf DNA / circulating tumor cell / HCC / CTC / lipid biopsy / 肝細胞癌 / 臨床 / 遺伝子 / 癌 / 効果予測因子 / cell free DNA / 効果予測 / 術前化学療法 Less
  • Research Projects

    (17 results)
  • Research Products

    (109 results)
  • Co-Researchers

    (24 People)
  •  Development of a Diagnostic Method for Distant Micrometastasis in Locally Advanced Colorectal Cancer Using ctDNA/RNA in Blood and Urinary Extracellular Vesicles

    • Principal Investigator
      上原 圭
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nippon Medical School
  •  exosomeおよびLarge-EV内のctDNAを用いた胃癌根治切除後の再発リスク判定法の開発

    • Principal Investigator
      柿沼 大輔
    • Project Period (FY)
      2024 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nippon Medical School
  •  大腸癌における血液および尿エクソソームDNAを用いた微小残存病変検出法の新規開発

    • Principal Investigator
      太田 竜
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nippon Medical School
  •  Identification of early postoperative recurrence of colorectal cancer liver metastases using ctDNA in exosome and L-EV

    • Principal Investigator
      神田 知洋
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nippon Medical School
  •  循環DNA,DNAseバランスからみた術後感染症およびその腫瘍学的予後悪化予測

    • Principal Investigator
      松田 明久
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Nippon Medical School
  •  Elucidate spatial and temporal heterogenity using extracellare vesiclesPrincipal Investigator

    • Principal Investigator
      山田 岳史
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nippon Medical School
  •  脾臓の抗腫瘍作用メカニズムの解明

    • Principal Investigator
      吉田 寛
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nippon Medical School
  •  The possibility of urinary circulating tumor DNA predicting the effect of chemotherapy and recurrence risk after curative resection in colorectal cancer

    • Principal Investigator
      Ohta Ryo
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nippon Medical School
  •  Liquid biopsy技術を加えた新たな胃癌進行度分類診断の研究

    • Principal Investigator
      金沢 義一
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nippon Medical School
  •  Relationship of circulating tumor cells and spleen

    • Principal Investigator
      Yoshida Hiroshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nippon Medical School
  •  Exploring an extracellular RNA-based innovative therapy for neuropathic pain

    • Principal Investigator
      Sakai Atsushi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      Nippon Medical School
  •  Identification and functional analysis of novel biomarker miRNA in cisplatin-induced muscle atrophy

    • Principal Investigator
      Sakai Hiroyasu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Hoshi University
  •  Optimization of Rectal Cancer Treatment by Gene Mutation Patterns in Liquid biopsy and Tumor Biopsy

    • Principal Investigator
      Suguru Hasegawa
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Fukuoka University
  •  New biomarker for recurrence of HCC by using liquid biopsy

    • Principal Investigator
      TANIAI NOBUHIKO
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nippon Medical School
  •  Mechanism for resistance EGFR blockade; Analysis using circulating tumor DNA and circulating tumor cellPrincipal Investigator

    • Principal Investigator
      Yamada Takeshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nippon Medical School
  •  Prognostic value of liquid biopsy in patients with rectal cancer treated with neoadjuvant chemotherapy

    • Principal Investigator
      Koizumi Michihiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nippon Medical School
  •  Interpretation for the mechanism of acquired resistance of EGFR blockade by using cell free DNAPrincipal Investigator

    • Principal Investigator
      Yamada Takeshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Nippon Medical School

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

  • [Journal Article] Analysis of Circulating DNA to Assess Prognoses for Metastatic Colorectal Cancer Patients Treated with Regorafenib Dose-Escalation Therapy: A Retrospective, Exploratory Analysis of the RECC Trial2023

    • Author(s)
      Ohta Ryo、Yamada Takeshi、Nakamura Masato、Enomoto Masanobu、Takahashi Makoto、Yokomizo Hajime、Kosugi Chihiro、Ishimaru Kei、Sonoda Hiromichi、Kuramochi Hidekazu、Yoshida Yoichiro、Furuya Shinji、Hirata Keiji、Yoshida Hiroshi、Nozawa Keijiro、Hashiguchi Yojiro, et al.
    • Journal Title

      Digestion

      Volume: 16 Issue: 3 Pages: 1-10

    • DOI

      10.1159/000528283

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10655, KAKENHI-PROJECT-22K08787, KAKENHI-PROJECT-22K08811
  • [Journal Article] Diagnosis of strangulated bowel obstruction using blood DNA-degrading enzyme activity2023

    • Author(s)
      Takuma IWAI
    • Journal Title

      Impact

      Volume: 2 Issue: 2 Pages: 39-41

    • DOI

      10.21820/23987073.2023.2.39

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K16582, KAKENHI-PROJECT-22K08811
  • [Journal Article] Clinical significance of the <i>KRAS G13D</i> mutation in anastomotic recurrence of colorectal cancer2023

    • Author(s)
      Matsunaga Keigo、Sasaki Kazuhito、Hata Keisuke、Nozawa Hiroaki、Kawai Kazushige、Murono Koji、Emoto Shigenobu、Yokoyama Yuichiro、Sonoda Hirofumi、Ueda Koji、Kuriyama Sho、Yamada Takeshi、Yoshida Hiroshi、Ishihara Soichiro
    • Journal Title

      Oncology Letters

      Volume: 25 Issue: 5 Pages: 192-192

    • DOI

      10.3892/ol.2023.13778

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08811, KAKENHI-PROJECT-21H02778
  • [Journal Article] Devascularization for peristomal varices: A video vignette2023

    • Author(s)
      Iwai Takuma、Shimizu Tetsuya、Yamada Takeshi、Yoshida Hiroshi
    • Journal Title

      Asian Journal of Surgery

      Volume: 46 Issue: 10 Pages: 4556-4557

    • DOI

      10.1016/j.asjsur.2023.05.019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08811
  • [Journal Article] Tumor DNA in Peritoneal Lavage as a Novel Biomarker for Predicting Peritoneal Recurrence in Patients With Gastric Cancer.2023

    • Author(s)
      Yukawa N, Yamada T, Aoyama T, Woo T, Ueda K, Mastuda A, Hara K, Kazama K, Tamagawa H, Sato T, Oshima T, Suzuki A, Aburatani H, Ishikawa S, Saito A, Masuda M, Yoshida H, Rino Y.
    • Journal Title

      Anticancer Res.

      Volume: 43(5) Issue: 5 Pages: 2069-2076

    • DOI

      10.21873/anticanres.16367

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07465, KAKENHI-PROJECT-22K08811, KAKENHI-PROJECT-22H04990
  • [Journal Article] 大腸癌リキッドバイオプシー2022

    • Author(s)
      山田岳史、太田竜、吉田寛
    • Journal Title

      メディカル・サイエンス・ダイジェスト

      Volume: 48 Pages: 9-12

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Journal Article] Relationship between perioperative oncological evaluation and recurrence using circulating tumor DNA with KRAS mutation in patients with colorectal cancer2022

    • Author(s)
      Takaomi Hayashi, Yoichiro Yoshida, Teppei Yamada, Keita Tanaka, Hideki Shimaoka, Ryuji Kajitani, Taro Munechika, Hideki Nagano, Yoshiko Matsumoto, Akira Komono, Ryohei Sakamoto, Naoya Aisu, Gumpei Yoshimatsu, Fumihiro Yoshimura, Suguru Hasegawa
    • Journal Title

      Cancer Medicine

      Volume: March21 Issue: 16 Pages: 1-10

    • DOI

      10.1002/cam4.4677

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08663
  • [Journal Article] Use of Liquid Biopsy to Detect <i>PIK3CA</i> Mutation in Metastatic Breast Cancer2022

    • Author(s)
      Nakai Maki、Yamada Takeshi、Sekiya Kenta、Sato Ai、Hankyo Meishi、Kuriyama Sho、Takahashi Goro、Kurita Tomoko、Yanagihara Keiko、Yoshida Hiroshi、Ohashi Ryuji、Takei Hiroyuki
    • Journal Title

      Journal of Nippon Medical School

      Volume: 89 Issue: 1 Pages: 66-71

    • DOI

      10.1272/jnms.JNMS.2022_89-107

    • NAID

      130007996010

    • ISSN
      1345-4676, 1347-3409
    • Year and Date
      2022-02-25
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08583, KAKENHI-PROJECT-19K09160, KAKENHI-PROJECT-22K08811
  • [Journal Article] BRAF V600E mutations in right-side colon cancer: Heterogeneity detected by liquid biopsy2022

    • Author(s)
      Ueda Koji、Yamada Takeshi、Ohta Ryo、Matsuda Akihisa、Sonoda Hiromichi、Kuriyama Sho、Takahashi Goro、Iwai Takuma、Takeda Kohki、Miyasaka Toshimitsu、Shinji Seiichi、Chika Noriyasu、Ishida Hideyuki、Yoshida Hiroshi
    • Journal Title

      European Journal of Surgical Oncology

      Volume: 48 Issue: 6 Pages: 1375-1383

    • DOI

      10.1016/j.ejso.2022.01.016

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08811
  • [Journal Article] A Trial Protocol of Precision Medicine for Patients with RAS Wild Metastatic Colorectal Cancer Using Liquid Biopsy (RAS-liquid Study): A Prospective, Multicenter Observational Study2022

    • Author(s)
      Matsuda Akihisa、Yamada Takeshi、Takahashi Takao、Hirata Keiji、Nagasaka Takeshi、Ishimaru Kei、Sakamoto Kazuhiro、Koda Keiji、Ishikawa Toshiaki、Ishida Hideyuki、Matsuda Kenji、Kuramochi Hidekazu、Yoshida Yoichiro、Sonoda Hiromichi、Yoshida Hiroshi
    • Journal Title

      Journal of the Anus, Rectum and Colon

      Volume: 6 Issue: 1 Pages: 52-57

    • DOI

      10.23922/jarc.2021-042

    • NAID

      130008145586

    • ISSN
      2432-3853
    • Year and Date
      2022-01-28
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09160, KAKENHI-PROJECT-22K08811
  • [Journal Article] Biomarkers for anti?vascular endothelial growth factor drugs2022

    • Author(s)
      Kuriyama Sho、Yamada Takeshi、Matsuda Akihisa、Takahashi Goro、Iwai Takuma、Takeda Kohki、Ueda Koji、Miyasaka Toshimitsu、Yokoyama Yasuyuki、Shinji Seiichi、Sonoda Hiromichi、Ohta Ryo、Yonaga Kazuhide、Kanaka Shintaro、Yoshida Hiroshi
    • Journal Title

      Oncology Letters

      Volume: 24 Issue: 6 Pages: 463-463

    • DOI

      10.3892/ol.2022.13583

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K08811
  • [Journal Article] Detection of KRAS mutations in circulating tumour DNA from plasma and urine of patients with colorectal cancer2021

    • Author(s)
      Ohta Ryo、Yamada Takeshi、Sonoda Hiromichi、Matsuda Akihisa、Shinji Seiichi、Takahashi Goro、Iwai Takuma、Takeda Kohki、Ueda Koji、Kuriyama Sho、Miyasaka Toshimitsu、Yokoyama Yasuyuki、Hara Keisuke、Yoshida Hiroshi
    • Journal Title

      European Journal of Surgical Oncology

      Volume: 47 Issue: 12 Pages: 3151-3156

    • DOI

      10.1016/j.ejso.2021.07.017

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09160, KAKENHI-PROJECT-20K09020
  • [Journal Article] リキッドバイオプシーの現況と展望2021

    • Author(s)
      山田岳史、太田竜、松田明久、園田寛道、進士誠一、吉田寛
    • Journal Title

      日本外科学会雑誌

      Volume: 122 Pages: 494-498

    • NAID

      40022701474

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Journal Article] Systemic Chemotherapy is a Promising Treatment Option for Patients with Colonic Stents: A Review2021

    • Author(s)
      Matsuda Akihisa、Yamada Takeshi、Matsumoto Satoshi、Shinji Seiichi、Ohta Ryo、Sonoda Hiromichi、Takahashi Goro、Iwai Takuma、Takeda Kohki、Sekiguchi Kumiko、Yoshida Hiroshi
    • Journal Title

      Journal of the Anus, Rectum and Colon

      Volume: 5 Issue: 1 Pages: 1-10

    • DOI

      10.23922/jarc.2020-061

    • NAID

      130007976101

    • ISSN
      2432-3853
    • Year and Date
      2021-01-28
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Journal Article] Methylation status and long‐fragment cell‐free DNA are prognostic biomarkers for gastric cancer2021

    • Author(s)
      Ko Kazuhide、Kananazawa Yoshikazu、Yamada Takeshi、Kakinuma Daisuke、Matsuno Kunihiko、Ando Fumihiko、Kuriyama Sho、Matsuda Akihisa、Yoshida Hiroshi
    • Journal Title

      Cancer Medicine

      Volume: 10 Issue: 6 Pages: 2003-2012

    • DOI

      10.1002/cam4.3755

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09160, KAKENHI-PROJECT-20K09045
  • [Journal Article] Oncological evaluation in the perioperative period using cfDNA with BRAF V600E mutation in patients with colorectal cancer2021

    • Author(s)
      Keita Tanaka, Yoichiro Yoshida, Teppei Yamada, Takaomi Hayashi, Hideki Shimaoka, Fumihiro Yoshimura, Ryuji Kajitani Taro Munechika, Yoshiko Matsumoto, Hideki Nagano, Akira Komono, Ryohei Sakamoto, Ryo Nakashima, Naoya Aisu, Gumpei Yoshimatsu, Suguru Hasegawa
    • Journal Title

      Scientific Reportsorts

      Volume: 11 Issue: 1 Pages: 1-7

    • DOI

      10.1038/s41598-021-92795-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08663
  • [Journal Article] Circulating cell-free long DNA fragments predict post-hepatectomy recurrence of colorectal liver metastases2020

    • Author(s)
      Iwai Takuma、Yamada Takeshi、Takahashi Goro、Takeda Kohki、Koizumi Michihiro、Shinji Seiichi、Matsuda Akihisa、Yokoyama Yasuyuki、Hara Keisuke、Ueda Kohji、Ohta Ryo、Taniai Nobuhiko、Yoshida Hiroshi
    • Journal Title

      European Journal of Surgical Oncology

      Volume: 46 Issue: 1 Pages: 108-114

    • DOI

      10.1016/j.ejso.2019.08.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10657, KAKENHI-PROJECT-19K09160
  • [Journal Article] Circulating cell-free long DNA fragments predict post-hepatectomy recurrence of colorectal liver metastases.2020

    • Author(s)
      Iwai T, Yamada T, Takahashi G, Takeda K, Koizumi M, Shinji S, Matsuda A, Yokoyama Y, Hara K, Ueda K, Ohta R, Taniai N, Yoshida H.
    • Journal Title

      Eur J Surg oncol

      Volume: 46(1) Pages: 108-114

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10678
  • [Journal Article] Even a partial pathological response is associated with lower relapse rates in patients with operable rectal cancer undergoing neoadjuvant chemotherapy2020

    • Author(s)
      Koizumi Michihiro、Yamada Takeshi、Shinji Seiichi、Matsuda Akihisa、Yokoyama Yasuyuki、Takahashi Goro、Iwai Takuma、Takeda Kohki、Hara Keisuke、Yoshida Hiroshi
    • Journal Title

      Journal of Surgical Oncology

      Volume: 123 Issue: 1 Pages: 286-292

    • DOI

      10.1002/jso.26245

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Journal Article] Prognostic Role of the Platelet-to-Lymphocyte Ratio for Patients With Metastatic Colorectal Cancer Treated With Aflibercept2020

    • Author(s)
      MATSUDA AKIHISA、YAMADA TAKESHI、MATSUMOTO SATOSHI、SHINJI SEIICHI、OHTA RYO、SONODA HIROMICHI、SHINOZUKA ERIKO、SEKIGUCHI KUMIKO、SUZUKI HIDEYUKI、YOSHIDA HIROSHI
    • Journal Title

      In Vivo

      Volume: 34 Issue: 5 Pages: 2667-2673

    • DOI

      10.21873/invivo.12086

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Journal Article] Oxaliplatin-induced increase in splenic volume: experiences from multicenter study in Japan2020

    • Author(s)
      Ohta Ryo、Yamada Takeshi、Hara Keisuke、Iwai Takuma、Tanakaya Kohji、Ishibashi Keiichiro、Yoshimatsu Kazuhiko、Kosugi Chihiro、Tsubaki Masahiro、Nakajima Hideo、Oya Masatoshi、Yoshida Hiroshi、Koda Keiji、Ishida Hideyuki
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 25 Issue: 12 Pages: 2075-2082

    • DOI

      10.1007/s10147-020-01763-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Journal Article] Combination of TAS-102 and bevacizumab as third-line treatment for metastatic colorectal cancer: TAS-CC3 study2020

    • Author(s)
      Yoshida Yoichiro、Yamada Takeshi、Yoshida Hiroshi
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 26 Issue: 1 Pages: 111-117

    • DOI

      10.1007/s10147-020-01794-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Journal Article] Emerging RAS, BRAF, and EGFR mutations in cell-free DNA of metastatic colorectal patients are associated with both primary and secondary resistance to first-line anti-EGFR therapy2020

    • Author(s)
      Yamada Takeshi、Matsuda Akihisa、Takahashi Goro、Iwai Takuma、Takeda Kohki、Ueda Kohji、Kuriyama Sho、Koizumi Michihiro、Shinji Seiichi、Yokoyama Yasuyuki、Ohta Ryo、Yoshida Hiroshi
    • Journal Title

      International Journal of Clinical Oncology

      Volume: 25 Issue: 8 Pages: 1523-1532

    • DOI

      10.1007/s10147-020-01691-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Journal Article] Upregulation of ubiquitinated proteins and their degradation pathway in muscle atrophy induced by cisplatin in mice2020

    • Author(s)
      Hiroyasu Sakai, Yohei Ikeno, Yuka Tsukimura, Maya Inomata, Yuta Suzuki, Risako Kon, Nobutomo Ikarashi, Yoshihiko Chiba, Takeshi Yamada, Junzo Kamei
    • Journal Title

      Toxicol Appl Pharmacol

      Volume: 403 Pages: 115165-115165

    • DOI

      10.1016/j.taap.2020.115165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06706
  • [Journal Article] In vitro and in vivo studies on the association of long non?coding RNAs H19 and urothelial cancer associated 1 with the susceptibility to 5?fluorouracil in rectal cancer2019

    • Author(s)
      Yokoyama Yasuyuki、Sakatani Takashi、Wada Ryuichi、Ishino Kousuke、Kudo Mitsuhiro、Koizumi Michihiro、Yamada Takeshi、Yoshida Hiroshi、Naito Zenya
    • Journal Title

      International Journal of Oncology

      Volume: 55 Pages: 1361-1371

    • DOI

      10.3892/ijo.2019.4895

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09160, KAKENHI-PROJECT-16K10479
  • [Journal Article] Liquid biopsy for the management of patients with colorectal cancer2019

    • Author(s)
      Yamada T, et al.
    • Journal Title

      Digestion

      Volume: 99 Issue: 1 Pages: 39-45

    • DOI

      10.1159/000494411

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10657, KAKENHI-PROJECT-17K10678, KAKENHI-PROJECT-16K10556
  • [Journal Article] Analysis of colorectal cancer‐related mutations by liquid biopsy: Utility of circulating cell‐free DNA and circulating tumor cells2019

    • Author(s)
      Takeda Kohki、Yamada Takeshi、Takahashi Goro、Iwai Takuma、Ueda Koji、Kuriyama Sho、Koizumi Michihiro、Matsuda Akihisa、Shinji Seiichi、Ohta Ryo、Yokoyama Yasuyuki、Hotta Masahiro、Hara Keisuke、Yoshida Hiroshi
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 11 Pages: 3497-3509

    • DOI

      10.1111/cas.14186

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09160, KAKENHI-PROJECT-17K10657
  • [Journal Article] Postoperative non‐steroidal anti‐inflammatory drugs and anastomotic leakage after gastrointestinal anastomoses: Systematic review and meta‐analysis2019

    • Author(s)
      Jamjittrong Supaschin、Matsuda Akihisa、Matsumoto Satoshi、Kamonvarapitak Tunyaporn、Sakurazawa Nobuyuki、Kawano Youichi、Yamada Takeshi、Suzuki Hideyuki、Miyashita Masao、Yoshida Hiroshi
    • Journal Title

      Annals of Gastroenterological Surgery

      Volume: 4 Issue: 1 Pages: 64-75

    • DOI

      10.1002/ags3.12300

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Journal Article] Establishment and characterization of a novel neuroendocrine carcinoma cell line derived from a human ascending colon tumor.2019

    • Author(s)
      Shinji S, Sasaki N, Yamada T, Koizumi M, Matsuda A, Ohta R, Yokoyama Y, Takahashi G, Hotta M, Hara K, Takeda K, Ueda K, Kuriyama S, Ishiwata T, Murakami T, Ueda Y, Kanazawa Y, Yoshida H.
    • Journal Title

      Cancer Sci.

      Volume: 110(12) Issue: 12 Pages: 3708-3717

    • DOI

      10.1111/cas.14221

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08276, KAKENHI-PROJECT-19K07685, KAKENHI-PROJECT-19K09160, KAKENHI-PROJECT-16K08263, KAKENHI-PROJECT-17K19341, KAKENHI-PROJECT-19K11759
  • [Journal Article] Feasibility of Neoadjuvant FOLFOX Therapy Without Radiotherapy for Baseline Resectable Rectal Cancer2018

    • Author(s)
      KOIZUMI MICHIHIRO、YAMADA TAKESHI、SHINJI SEIICHI、YOKOYAMA YASUYUKI、TAKAHASHI GORO、IWAI TAKUMA、TAKEDA KOHKI、HARA KEISUKE、OHTA KEIICHIRO、UCHIDA EIJI、YOSHIDA HIROSHI
    • Journal Title

      In Vivo

      Volume: 32 Issue: 4 Pages: 937-943

    • DOI

      10.21873/invivo.11332

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Journal Article] Oncological Assessment of Stent Placement for Obstructive Colorectal Cancer from Circulating Cell-Free DNA and Circulating Tumor DNA Dynamics2018

    • Author(s)
      Takahashi Goro、Yamada Takeshi、Iwai Takuma、Takeda Kohki、Koizumi Michihiro、Shinji Seiichi、Uchida Eiji
    • Journal Title

      Annals of Surgical Oncology

      Volume: 25 Issue: 3 Pages: 737-744

    • DOI

      10.1245/s10434-017-6300-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Journal Article] Evaluation of liquid biopsies for detection of emerging mutated genes in metastatic colorectal cancer2018

    • Author(s)
      Furuki H, Yamada T, et al.
    • Journal Title

      European Journal of Surgical Oncology

      Volume: 18 Issue: 7 Pages: 975-982

    • DOI

      10.1016/j.ejso.2018.01.224

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10657, KAKENHI-PROJECT-17K10678, KAKENHI-PROJECT-16K10556
  • [Journal Article] Utility of KRAS mutation detection using circulating cell-free DNA from patients with colorectal cancer2016

    • Author(s)
      Takeshi Yamada, Goro Takahashi, Takuma Iwai, et al.
    • Journal Title

      Cancer Science

      Volume: 107 Issue: 7 Pages: 936-43

    • DOI

      10.1111/cas.12959

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462030
  • [Journal Article] Utility of KRAS mutation detection using circulating cell-free DNA from patients with colorectal cancer2016

    • Author(s)
      山田岳史
    • Journal Title

      Cancer Science

      Volume: 未定

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26462030
  • [Presentation] Impact of RAS and BRAF heterogeneity on the efficacy of EGFR blockade in patients with metastatic colorectal cancer.2023

    • Author(s)
      山田岳史
    • Organizer
      ASCO-GI
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08787
  • [Presentation] Detection of RAS mutations in colorectal cancer patients using DNA from extracellular vesicles2023

    • Author(s)
      栗山翔、山田岳史
    • Organizer
      American Association for Cancer Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08787
  • [Presentation] 尿と細胞外小胞を用いた大腸癌Liquid biopsy2023

    • Author(s)
      山田岳史、吉田寛
    • Organizer
      第109回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-22K08811
  • [Presentation] Impact of RAS and BRAF heterogeneity on the efficacy of EGFR blockade in patients with metastatic colorectal cancer.2023

    • Author(s)
      Yamada T, et al.
    • Organizer
      ASCO Gastrointestinal Cancers Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08787
  • [Presentation] オキサリプラチン誘発性末梢神経傷害におけるバイオマーカー探索2023

    • Author(s)
      坂井 敦,山田 岳史,丸山 基世,吉田 寛,鈴木 秀典
    • Organizer
      生理学研究所研究会 痛み研究会2022
    • Data Source
      KAKENHI-PROJECT-19H03552
  • [Presentation] 尿と細胞外小胞を用いた大腸癌Liquid biopsy2023

    • Author(s)
      山田岳史
    • Organizer
      日本消化器病学会
    • Data Source
      KAKENHI-PROJECT-22K08787
  • [Presentation] ふたつのHeterogeneityが抗EGFR抗体の治療効果に与える影響2023

    • Author(s)
      山田岳史、他
    • Organizer
      日本消化器外科学会
    • Data Source
      KAKENHI-PROJECT-22K08787
  • [Presentation] Precision medicine for patients with colorectal cancer using liquid biopsy2023

    • Author(s)
      Yamada T, et al.
    • Organizer
      日本癌治療学会
    • Data Source
      KAKENHI-PROJECT-22K08787
  • [Presentation] 尿中circulating tumor DNAを用いた大腸癌KRAS遺伝子解析の有用性2022

    • Author(s)
      太田 竜, 山田 岳史, 園田 寛道, 松田 明久, 進士 誠一, 代永 和秀, 岩井 拓磨, 武田 幸樹, 上田 康二, 栗山 翔, 宮坂 俊 光, 吉田 寛
    • Organizer
      第47回日本外科系連合学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K09020
  • [Presentation] 消化管疾患のLiquid biopsy2022

    • Author(s)
      山田岳史
    • Organizer
      日本消化管学会
    • Data Source
      KAKENHI-PROJECT-22K08787
  • [Presentation] オキサリプラチン誘発性末梢神経障害を予測する血中長鎖非コードRNAバイオマーカーの探索2022

    • Author(s)
      坂井敦、丸山基世、山田岳史、吉田寛、鈴木秀典
    • Organizer
      第95回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-19H03552
  • [Presentation] ふたつのHeterogeneityがもたらす大腸癌の難治性とその克服2022

    • Author(s)
      山田岳史
    • Organizer
      Japan Digestive Disease Week 2002
    • Data Source
      KAKENHI-PROJECT-22K08787
  • [Presentation] Circulating tumor DNA を 用 い た personal biomarker2021

    • Author(s)
      高橋 吾郎,山田 岳史,太田 竜,園田 寛道,進士 誠一,松田 明久,岩井 拓磨,武田 幸樹,上田 康二,栗山 翔,宮坂 俊光,吉田 寛
    • Organizer
      第121回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] PIK3CA 変異大腸癌に対するリキッドバイオプシーの検討2021

    • Author(s)
      坂 俊光,山田 岳史,園田 寛道,進士 誠一,松田 明久,太田 竜,高橋 吾郎,岩井 拓磨,武田 幸樹,上田 康二,栗山 翔,吉田 寛
    • Organizer
      第121回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] Liquid biopsyを用いた大腸癌肝転移に対するPrecision Surgery2021

    • Author(s)
      山田 岳史, 小泉 岐博, 松田 明久, 進士 誠一, 太田 竜, 横山 康行, 高橋 吾郎, 武田 幸樹, 古木 裕康, 原 敬介, 上田 康二, 栗山 翔, 岩井 拓磨, 吉田 寛
    • Organizer
      日本大腸肛門病学会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] iPS細胞由来一次感覚神経から放出される長鎖非コードRNAのオキサリプラチン誘発性神経障害に対するバイオマーカーとしての検討2021

    • Author(s)
      坂井敦、丸山基世、山田岳史、鈴木秀典
    • Organizer
      第43回日本疼痛学会
    • Data Source
      KAKENHI-PROJECT-19H03552
  • [Presentation] 尿中循環腫瘍 DNAを用いた大腸癌KRAS遺伝子解析の有用性2021

    • Author(s)
      太田 竜, 山田 岳史, 園田 寛道, 松田 明久, 進士 誠一, 代永 和秀, 岩井 拓磨, 武田 幸樹, 上田 康二, 栗山 翔, 宮坂 俊 光, 吉田 寛
    • Organizer
      第32回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-20K09020
  • [Presentation] Liquid biopsyによる右側結腸癌におけるBRAF V600E遺伝子変異の同定とHeterogeneity2020

    • Author(s)
      上田 康二, 山田 岳史, 松田 明久, 進士 誠一, 太田 竜, 園田 寛道, 高橋 吾郎, 栗山 翔, 石田 秀行, 吉田 寛
    • Organizer
      第75回日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] リキッドバイオプシーによる大腸癌BRAF V600Eの周術期経時的評価2020

    • Author(s)
      田中 敬太, 吉田 陽一郎, 山田 哲平, 島岡 秀樹, 林 貴臣, 薦野 晃, 愛洲 尚哉, 吉松 軍平, 吉村 文博, 長谷川 傑
    • Organizer
      第75回日本消化器外科学会
    • Data Source
      KAKENHI-PROJECT-18K08663
  • [Presentation] exosomal DNAによる循環腫瘍DNAの検出の可能性2020

    • Author(s)
      栗山 翔, 山田 岳史, 進士 誠一, 松田 明久, 園田 寛道, 太田 竜, 高橋 吾郎, 岩井 拓磨, 武田 幸樹, 上田 康二, 宮坂 俊光, 吉田 寛
    • Organizer
      第79回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] 消化器悪性疾患に対するconversion surgery Liquid biopsyを用いた大腸癌肝転移のConversion surgery2020

    • Author(s)
      山田 岳史, 松田 明久, 吉田 寛
    • Organizer
      日本消化器病学会大会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] The pretreatment lymphocyte-to-monocyte ratio (LMR) to predict treatment efficacy and prognosis in metastatic colorectal cancer treated with the combination of TAS-102 and bevacizumab (TAS-CC3 Study).2020

    • Author(s)
      Matsuda A, Yoshida Y, Kamiyama H, Kosugi C, Yoshida H, Ishibashi K, Ihara K, Takahashi M, Kuramochi H, Fukazawa A, Sonoda H, Yoshimatsu K, Yamaguchi S, Ishida H, Hasegawa S, Yamada T, Sakamoto K, Koda K
    • Organizer
      2020 Gastrointestional Cancers Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] Exosomal DNAによる微小遺残病変検出の可能性2020

    • Author(s)
      栗山 翔, 山田 岳史, 松田 明久, 進士 誠一, 園田 寛道, 太田 竜, 横山 康行, 高橋 吾郎, 岩井 拓磨, 武田 幸樹, 原 敬介, 上田 康二, 宮坂 俊光, 吉田 寛
    • Organizer
      第58回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] Regorafenib does escalation therapy for patients with refractory metastatic colorectal cancer (RECC Study).2020

    • Author(s)
      Nakamura M, Yamada T, Ishiyama S, Enomoto M, Yokomizo H, Kosugi C, Sonoda H, Ishimaru K, Ishibashi K, Kuramochi H, Nozawa K, Ohta R, Takahashi M, Yoshida H, Hashiguchi Y, Hirata K, Katsumata K, Katsumata K, Ishida H, Koda K, Sakamoto K
    • Organizer
      2020 Gastrointestional Cancers Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] 抗体ビーズ及びマイクロ流体デバイスを用いた Circulating Tumor Cells の分離2020

    • Author(s)
      太田竜、山田岳史、武田幸樹、小泉岐博、松田明久、進士誠一、高橋吾郎、堀田正啓、原敬介、上田康二、栗山翔、吉田寛、高屋智之、上野寿美、中山雅人
    • Organizer
      第4回 Liquid Biopsy 研究会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] 目を見張る進歩をきたしたリキッドバイオプシー 消化器癌Liquid biopsyの進歩2020

    • Author(s)
      山田 岳史, 松田 明久, 太田 竜, 園田 寛道, 進士 誠一, 高橋 吾郎, 岩井 拓磨, 武田 幸樹, 上田 康二, 栗山 翔, 宮坂 俊光, 原 敬介, 横山 康行, 吉田 寛
    • Organizer
      第58回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] 閉塞性大腸癌に対する安全かつ効果的なBTS―根治性を考慮したバンドル管理の重要性―2020

    • Author(s)
      松田明久、高橋吾郎、豊田哲鎬、山田岳史、松本智司、小泉岐博、進士誠一、太田竜、横山康行、関口久美子、吉田寛
    • Organizer
      第56回日本腹部救急医学会総会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] 大腸癌終末期におけるcf DNA量の変化2020

    • Author(s)
      栗山 翔, 山田 岳史, 松田 明久, 小泉 岐博, 進士 誠一, 太田 竜, 高橋 吾郎, 堀田 正啓, 原 敬介, 武田 幸樹, 上田 康二, 吉田 寛
    • Organizer
      日本臨床栄養代謝学会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] Liquid biopsyを用いた高度進行直腸癌の集学的治療2019

    • Author(s)
      山田岳史
    • Organizer
      JDDW
    • Data Source
      KAKENHI-PROJECT-17K10657
  • [Presentation] シスプラチン誘発筋萎縮マウスにおけるユビキチン遺伝子の発現増加2019

    • Author(s)
      月村友香、猪俣茉耶、鈴木悠太、竹内滉人、原田優衣、里 史明、今理紗子、五十嵐信智、山田岳史、亀井淳三、酒井寛泰
    • Organizer
      日本薬学会第139回年会
    • Data Source
      KAKENHI-PROJECT-18K06706
  • [Presentation] シスプラチン誘発筋萎縮におけるメカセルミンの効果2019

    • Author(s)
      原田優衣, 浅見真穂, 竹内滉人, 鈴木悠太, 内藤宏秋, 木寅聡子, 里 史明, 山田岳史, 今理紗子, 五十嵐信智, 亀井淳三, 酒井寛泰
    • Organizer
      第13回日本緩和医療薬学会年会
    • Data Source
      KAKENHI-PROJECT-18K06706
  • [Presentation] エイコサペンタエン酸によるシスプラチン誘発筋萎縮時のユビキチンおよびユビキチン化タンパク質量の低下作用2019

    • Author(s)
      猪俣茉耶, 月村友香, 里 史明, 今理紗子, 五十嵐信智, 山田岳史, 千葉義彦, 亀井淳三, 酒井寛泰
    • Organizer
      第140回日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-18K06706
  • [Presentation] シスプラチン誘発筋萎縮時の mir-29-3p の発現増加とIGF-1発現低下2019

    • Author(s)
      竹内滉人, 内藤宏秋, 鈴木悠太, 原田優衣, 浅見真穂, 木寅聡子, 里 史明, 山田岳史, 今理紗子, 五十嵐信智, 亀井淳三, 酒井寛泰
    • Organizer
      第13回日本緩和医療薬学会年会
    • Data Source
      KAKENHI-PROJECT-18K06706
  • [Presentation] シスプラチン誘発筋萎縮時の Ubb、Ubc、Rps27a および Uba52 遺伝子の発現増加とユビキチン化タンパク質の分解機序2019

    • Author(s)
      月村友香, 猪俣茉耶, 里 史明, 今理紗子, 五十嵐信智, 山田岳史, 千葉義彦, 亀井淳三, 酒井寛泰
    • Organizer
      第140回日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-18K06706
  • [Presentation] Liquid biopsy を用いた大腸癌に対する real-time precision medicine2019

    • Author(s)
      山田岳史
    • Organizer
      第119回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-19K09160
  • [Presentation] シスプラチン誘発筋萎縮時の血漿サンプル中の mir-5129-5p の発現変化2019

    • Author(s)
      木寅聡子、浅見真穂、内藤宏秋、鈴木悠太、竹内滉人、原田優衣、里 史明、山田岳史、亀井淳三、酒井寛泰
    • Organizer
      日本薬学会第139回年会
    • Data Source
      KAKENHI-PROJECT-18K06706
  • [Presentation] Liquid biopsyを用いた大腸癌Precision Surgery2019

    • Author(s)
      山田岳史
    • Organizer
      日本癌治療学会
    • Data Source
      KAKENHI-PROJECT-17K10657
  • [Presentation] Liquid biopsyを用いた大腸癌real-time precision medicine2019

    • Author(s)
      山田岳史
    • Organizer
      日本消化器病学会
    • Data Source
      KAKENHI-PROJECT-17K10657
  • [Presentation] シスプラチン誘発筋萎縮時の骨格筋由来のIGF-1発現低下2019

    • Author(s)
      内藤宏秋、浅見真穂、木寅聡子、鈴木悠太、竹内滉人、原田優衣、里 史明、山田岳史、今 理紗子、五十嵐信智、亀井淳三、酒井寛泰
    • Organizer
      日本薬学会第139回年会
    • Data Source
      KAKENHI-PROJECT-18K06706
  • [Presentation] シスプラチン誘発筋萎縮時のユビキチン遺伝子発現増加におけるエイコサペンタエン酸の抑制効果2019

    • Author(s)
      猪俣茉耶、月村友香、里 史明、鈴木悠太、竹内滉人、原田優衣、今理紗子、五十嵐信智、山田岳史、亀井淳三、酒井寛泰
    • Organizer
      日本薬学会第139回年会
    • Data Source
      KAKENHI-PROJECT-18K06706
  • [Presentation] Liquid biopsyを用いた切除不能RAS野生型大腸癌に対する抗EGFR抗体による早期腫瘍縮小効果の予測2018

    • Author(s)
      山田岳史、他
    • Organizer
      日本外科学会
    • Data Source
      KAKENHI-PROJECT-17K10657
  • [Presentation] Emergence of KRAS mutation may play a major role in the secondary resistance to EGFR blockade2018

    • Author(s)
      Yamada T, et al
    • Organizer
      ESMO-GI
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10657
  • [Presentation] Distal intramural spread of rectal cancer following neoadjuvant chemotherapy without radiotherapy2018

    • Author(s)
      Koizumi M, Yamada T, Shinji S, Yokoyama Y, Takahashi G, Hotta M, Takeda K, Iwai T, Hara K, Ueda K, Takeda K, ,Ohta K, Yoshida H.
    • Organizer
      14th European Society of Coloproctology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Presentation] Emergence of KRAS mutation may play a major role in the secondary resistance to EGFR blochade.2018

    • Author(s)
      Yamada T, et al
    • Organizer
      ESMO-GI
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10678
  • [Presentation] Detection of colorectal cancer related gene mutations from CTC and ctDNA.2018

    • Author(s)
      Takeda K, Yamada T, Koizumi M, Shinji S, Yokoyama Y, Takahashi G, Iwai T, Hotta M, Furuki H, Uchida E
    • Organizer
      American Association of Cancer Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Presentation] Liquid biopsyを用いたReal-time Precision Medicine2018

    • Author(s)
      山田岳史、他
    • Organizer
      日本消化器外科学会
    • Data Source
      KAKENHI-PROJECT-17K10657
  • [Presentation] Emergence of KRAS mutation may play a major role in the secondary resistance to EGFR blockade2018

    • Author(s)
      Yamada Y, et al
    • Organizer
      ESMO-GI
    • Data Source
      KAKENHI-PROJECT-17K10657
  • [Presentation] Liquid biopsyを用いたRAS野生型大腸癌の個別化治療2018

    • Author(s)
      山田岳史、他
    • Organizer
      日本消化器病学会
    • Data Source
      KAKENHI-PROJECT-17K10657
  • [Presentation] 術前化学療法を行なった 直腸癌腹腔鏡下手術例の検討2018

    • Author(s)
      小泉岐博 山田岳史 進士誠一 横山康行 高橋吾郎  堀田正啓 岩井拓磨 原敬敬介 武田幸樹 上田康二 金沢義一 太田惠一朗 吉田寛
    • Organizer
      日本内視鏡外科学会総会
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Presentation] liquid biopsyを用いた大腸癌肝転移術後の微小残存病変検出の可能性2018

    • Author(s)
      古木裕康、山田岳史、谷合信彦、他
    • Organizer
      日本消化器癌発生学会
    • Data Source
      KAKENHI-PROJECT-17K10678
  • [Presentation] Detection of emerging somatic mutations in metastatic colorectal cancer using original custom panel of NGS2018

    • Author(s)
      古木裕康、山田岳史、谷合信彦、他
    • Organizer
      日本消化器外科学会
    • Data Source
      KAKENHI-PROJECT-17K10678
  • [Presentation] Circulating cell free DNAを用いたreal-timeな分子情報に基づく大腸癌化学療法2018

    • Author(s)
      山田岳史 , 高橋吾郎 , 岩井拓磨 , 武田幸樹 , 小泉 岐博
    • Organizer
      日本大腸肛門病学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Presentation] liquid biopsyを用いた切除不能RAS野生型大腸癌に対する抗EDFR抗体による早期腫瘍縮小効果の予測2018

    • Author(s)
      山田岳史、他
    • Organizer
      日本外科学会
    • Data Source
      KAKENHI-PROJECT-17K10678
  • [Presentation] Clinical Stage II/III直腸癌に対するneoadjuvant chemotherapy2018

    • Author(s)
      小泉 岐博、山田 岳史、進士 誠一、横山 康行、高橋 吾郎、堀田 正啓、岩丼 拓磨、 原 敬介、武田 幸樹、上田 康二、金沢 義一、太田恵―朗、内田 英二
    • Organizer
      日本大腸肛門病学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Presentation] Circulating tumor DNAを用いた大腸癌肝転移術後の早期再発危険群の同定2018

    • Author(s)
      古木裕康、山田岳史、谷合信彦、他
    • Organizer
      日本外科学会
    • Data Source
      KAKENHI-PROJECT-17K10678
  • [Presentation] 筋線維芽細胞にけるシスプラチン誘発ユビキチン化タンパク質の増加およびエイコサペンタエン酸の抑制効果2018

    • Author(s)
      酒井寛泰、猪俣茉耶、 月村友香、 内藤宏秋、 木寅聡子、 浅見真穂、甲斐友規、里 史明、湯本哲郎、山田岳史
    • Organizer
      第12回日本緩和医療薬学会年会
    • Data Source
      KAKENHI-PROJECT-18K06706
  • [Presentation] Liquid biopsyを用いた消化器がんMulti-biopsy Bank Project2018

    • Author(s)
      山田岳史 , 高橋吾郎 , 岩井拓磨 , 武田幸樹 , 上田康二 , 小泉 岐博
    • Organizer
      日本外科系連合学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Presentation] 直腸癌に対する術前化学療法の意義 ― 術前化学療法例と手術先行例の比較 ―2018

    • Author(s)
      小泉岐博 山田岳史 進士誠一 横山康行 高橋吾郎 堀田正啓 岩井拓磨 原啓介 武田幸樹 菅隼人 太田惠一郎 内田英二
    • Organizer
      日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Presentation] Liqid biopsyを用いたReal-time Precision Medicine2018

    • Author(s)
      山田岳史、他
    • Organizer
      日本消化器外科学会
    • Data Source
      KAKENHI-PROJECT-17K10678
  • [Presentation] 術前化学療法を行った直腸癌症例における循環血液中cell-free DNAを用いた予後予測2017

    • Author(s)
      小泉岐博 山田岳史 進士誠一 横山康行 高橋吾郎 堀田正啓 岩井拓磨 原敬介 武田幸樹 太田惠一朗 内田英二
    • Organizer
      第72回 日本消化器外科学会総会
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Presentation] Liquid Biopsyによる大腸癌肝転移肝切後再発高リスク症例に対する新バイオマーカー2017

    • Author(s)
      谷合信彦、山田岳史、吉田寛
    • Organizer
      第53回日本肝臓学会総会
    • Data Source
      KAKENHI-PROJECT-17K10678
  • [Presentation] Emergence of KRAS mutations contributes to acquired resistance to EGFR blockade2017

    • Author(s)
      Takeshi Yamada
    • Organizer
      American Association for Cancer Research
    • Place of Presentation
      Washington
    • Year and Date
      2017-04-01
    • Data Source
      KAKENHI-PROJECT-26462030
  • [Presentation] Emergence of KRAS mutations and acquisition of resistance to EGFR blockade2017

    • Author(s)
      Yamada T, et al
    • Organizer
      ASCI
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K10657
  • [Presentation] The prognostic value of pathological response in rectal cancer patients receiving neoadjuvant FOLFOX2017

    • Author(s)
      Michihiro Koizumi, Takeshi Yamada, Seiichi Shinji, Yasuyuki Yokoyama, Goro Takahashi, Masahiro Hotta, Takuma Iwai, Keisuke Hara, Kohki Takeda, Keiichiro Oota, Eiji Uchida
    • Organizer
      European Society of Coloproctology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Presentation] 術前化学療法を行った直腸癌症例におけるdおtal spreadの検討2017

    • Author(s)
      小泉岐博 山田岳史 進士誠一 横山康行 高橋吾郎 堀田正啓 岩井拓磨 原敬介 武田幸樹 太田惠一朗 内田英二
    • Organizer
      第117回 日本外科学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Presentation] Tracking emerging KRAS, BRAF and EGFR mutations through circulating cell-free DNA in patients with colorectal cancers treated by epidermal growth factor receptor blockade2017

    • Author(s)
      Takeshi Yamada
    • Organizer
      ASCO-Gastrointestinal Cancer Symposium
    • Place of Presentation
      San Francisco
    • Year and Date
      2017-02-19
    • Data Source
      KAKENHI-PROJECT-26462030
  • [Presentation] 術前化学療法施行した直腸癌症例における腹腔鏡下手術の短期成績2017

    • Author(s)
      小泉岐博 山田岳史 進士誠一 横山康行 高橋吾郎 堀田正啓 岩井拓磨 原敬介 武田幸樹 太田惠一朗 内田英二
    • Organizer
      第30回 日本内視鏡外科学会総会
    • Data Source
      KAKENHI-PROJECT-16K10556
  • [Presentation] Prediction and response evaluation of EGFR blockade for colorectal cancer by using circulating cell free DNA2016

    • Author(s)
      Takeshi Yamada
    • Organizer
      American Association for Cancer Research
    • Place of Presentation
      New Orleans
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462030
  • [Presentation] Tracking emerging KRAS and BRAF mutations through ccfDNA in colorectal cancers treated with EGFR blockade2016

    • Author(s)
      Takeshi Yamada
    • Organizer
      European Society for Medical Oncology
    • Place of Presentation
      Copenhagen
    • Year and Date
      2016-10-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462030
  • [Presentation] Prediction and response evaluation of EGFR blockade for colorectal cancer by using circulating cell free DNA2015

    • Author(s)
      岩井拓磨、山田岳史
    • Organizer
      AACR2015
    • Place of Presentation
      Philadelphia
    • Year and Date
      2015-04-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26462030
  • [Presentation] Prediction for efficacy and resistance of EGFR blockade by using liquid biopsy2014

    • Author(s)
      Yamada T, Kan H, Uchida E
    • Organizer
      Japan Digestive Disease Week 2014
    • Place of Presentation
      神戸
    • Year and Date
      2014-10-23
    • Data Source
      KAKENHI-PROJECT-26462030
  • [Presentation] Liquid biopsy detection of KRAS and BRAF mutations may be useful as a prognostic or predictive marker

    • Author(s)
      T.Yamada
    • Organizer
      European society for medical oncology 40
    • Place of Presentation
      Madrid
    • Year and Date
      2014-09-26 – 2014-09-30
    • Data Source
      KAKENHI-PROJECT-26462030
  • [Presentation] An Ultrasensitive Molecular Diagnostic Method for Blood Biopsy in Personalized Treatment of Colorectal Cancer

    • Author(s)
      S. Kitano, T. Yamada
    • Organizer
      European society for medical oncology 40
    • Place of Presentation
      Madrid
    • Year and Date
      2014-09-26 – 2014-09-30
    • Data Source
      KAKENHI-PROJECT-26462030
  • [Presentation] 大腸癌分子治療におけるliquid biopsyを利用したreal-time personalized therapy

    • Author(s)
      山田岳史
    • Organizer
      第69回日本消化器外科学会
    • Place of Presentation
      郡山
    • Year and Date
      2014-07-16 – 2014-07-18
    • Data Source
      KAKENHI-PROJECT-26462030
  • [Presentation] Real time personalized therapy for colorectal cancer by using liquid biopsy

    • Author(s)
      Yamada T, Kan H, Matsumoto S, Koizumi M, Shinji S, Matsuda A, Yamagishi A, Yokoyama Y, Iwai T, Uchida E
    • Organizer
      第25回日本消化器癌発生学会総会
    • Place of Presentation
      福岡
    • Year and Date
      2014-11-13 – 2014-11-14
    • Data Source
      KAKENHI-PROJECT-26462030
  • 1.  Koizumi Michihiro (40328802)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 15 results
  • 2.  Yoshida Hiroshi (60246999)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 32 results
  • 3.  Ohta Ryo (30839824)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 4.  TANIAI NOBUHIKO (20287725)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  Sakai Hiroyasu (00328923)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 6.  Suguru Hasegawa (10362500)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  Sakai Atsushi (30386156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  内田 英二 (70176684)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 9.  吉田 陽一郎 (70580265)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 10.  齋藤 文仁 (20360175)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  丸山 基世 (60709757)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  金沢 義一 (60307907)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  松田 明久 (00366741)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  松谷 毅 (50366712)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  清水 哲也 (60421195)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  上原 圭 (50467320)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  柿沼 大輔 (50516028)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  神田 知洋 (30714761)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  吉岡 正人 (80366715)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  橋口 陽二郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  岩井 拓磨
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  村上 孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  禹 哲漢
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  益田 宗孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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