SHIBATA Naohiro 柴田尚宏

… Alternative Names

柴田尚宏シバタナオヒロ

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Researcher Number	50311402
External Links
Affiliation (based on the past Project Information) *help	2008: National Institute of Infectious Diseases, 国立感染症研究所・細菌第二部, 主任研究官 2007 – 2008: National Institute of Infectious Diseases, 細菌第二部, 主任研究官 2004 – 2005: 国立感染症研究所, 細菌第二部, 主任研究官 2004 – 2005: 国立感染症研究所, 細菌第二部, 研究員 2002: 国立感染症研究所, 細菌第二部, 研究員 2001: 国立感染症研究所, 細菌・血液製剤部, 研究員
Review Section/Research Field	Principal Investigator Laboratory medicine / Bacteriology (including Mycology) Except Principal Investigator Bacteriology (including Mycology) / Biological Sciences
Keywords	Principal Investigator 薬剤耐性菌 / メタロ-β-ラクタマーゼ / グラム陰性桿菌 / 検出法 / 基質拡張型β-ラクタマーゼ / gram-negative bacteria / drug-resistance / genetic typing / metallo-beta-lactamase / メトロ-β-ラクタマーゼ … More / 迅速検出法 / 腸内細菌 / 迅速検出 / 基質特異性拡張型β-ラクタマーゼ / CTX-M β-ラクタマーゼ / インテグロン / 院内感染 … More Except Principal Investigator インテグラーゼ / vanA / VRE / AAC(6')-Ib / IMP-1 / IntI3 / Klebsiella pneumoniae / Serratia marcescens / 再配列 / 耐性遺伝子 / カルバペネム耐性 / OXA型β-ラクタマーゼ / アシネトバクター / クラス3インテグロン / 遺伝子転位機構 / 薬剤耐性菌 / κ γ-エレメント / 遺伝子再配列 / 挿入配列 / 遺伝子カセット / κγ-エレメント / トランスポゾン / インテグロン / 薬剤耐性遺伝子 Less

Molecular mechanism of accumulation and rearrangement of antibiotic resistance gene in bacteria.
- Principal Investigator
  
  ARAKAWA Yoshichika
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  National Institute of Infectious Diseases
Detection methods and survey of drug -resistance in Gram-Negative bacteria except Escherichia coli and Klebsiella spp.Principal Investigator
- Principal Investigator
  
  柴田尚宏
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  National Institute of Infectious Diseases
多剤耐性病原細菌における薬剤耐性遺伝子の集積および再配列機構に関する研究
- Principal Investigator
  
  ARAKAWA Yoshichika
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Infectious Diseases
Genetic typing and clinical method of detecting metallo-beta-lactamase-producers in gram-negative rods in JapanPrincipal Investigator
- Principal Investigator
  
  SHIBATA Naohiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  National Institute of Infectious Diseases, Japan
グラム陰性桿菌におけるメタロ-β-ラクタマーゼおよび基質拡張型β-ラクタマーゼ遺伝子の解析Principal Investigator
- Principal Investigator
  
  柴田尚宏
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  National Institute of Infectious Diseases

All 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation

[Journal Article] Change in the prevalence of extended-spectrum-beta-lactamase-producing Esherichia coli2009
- Author(s)
  Suzuki S, Shibata N, Yamane K, et al.
- Journal Title
  
  J Antimicrob Chemother 63
  
  Pages: 72-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590579
[Journal Article] Change in the prevalence of extended-spectrum-beta-lactamase-producing Esherichia coli in Japan by clonal spread.2009
- Author(s)
  Suzuki S, Shibata N, Yamane K, et al.
- Journal Title
  
  J Antimicrob Chemother 63
  
  Pages: 72-79
- Data Source
  KAKENHI-PROJECT-19590579
[Journal Article] カルバペネム耐性菌の検出法2008
- Author(s)
  柴田尚宏
- Journal Title
  
  医歯薬出版株式会社 36
  
  Pages: 1261-1268
- Data Source
  KAKENHI-PROJECT-19590579
[Journal Article] First molecular characterization of group B streptcocci with reduced penicillin susceptibilit2008
- Author(s)
  Kimura K, Suzuki S, Shibata N, et al.
- Journal Title
  
  Antimicrob agents Chemother 52
  
  Pages: 2890-2897
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590579
[Journal Article] First molecular characterization of group B streptcocci with reduced penicillin susceptibility.2008
- Author(s)
  Kimura K, Suzuki S,Shibata N, et al.
- Journal Title
  
  Antimicrob agents Chemother. 52
  
  Pages: 2890-2897
- Data Source
  KAKENHI-PROJECT-19590579
[Journal Article] MDRPの検出法2008
- Author(s)
  柴田尚宏
- Journal Title
  
  医歯薬出版株式会社 36
  
  Pages: 1261-1268
- Data Source
  KAKENHI-PROJECT-19590579
[Journal Article] New Plasmid-Mediated Fluoroquinolone Efflux Pump,QepA,Found in an Escherichia coli Clinical Isolate.2007
- Author(s)
  Yamane K, Wachino J, Suzuki S, Kimura K, Shibata N, Kato H, Shibayama K, Konda T, and Arakawa Y.
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 51(9)
  
  Pages: 3354-3360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590579
[Journal Article] Outbreak of CTX-M-3-type extended-spectrum β-lactamase-producing Enterobacter cloacae in a pediatric ward.2007
- Author(s)
  Moriguchi N, Itahashi Y, Tabata N, Yamazumi T, Furuta I, Shibata N, Arakawa Y and Miyata M.
- Journal Title
  
  J of Infection and Chemotherapy 13(4)
  
  Pages: 263-266
- NAID
  10019548121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590579
[Journal Article] Novel Plasmid-Mediated 16S rRNA m^1A1408 Methyltransferase,NpmA,Found in a Clinically Isolated Escherichia coli Strain Resistant to Structurally Diverse Aminoglycosides2007
- Author(s)
  Wachino J, Shibayama K, Kurokawa H, Kimura K, Yamane K, Satowa Suzuki, Shibata N, Ike Y, and Arakawa Y.
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 51(12)
  
  Pages: 4401-4409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590579
[Journal Article] PCR Classification of CTX-M-Type Beta-Lactamase Genes Identified in Clinically Isolated Gram-Negative Bacilli in Japan.2006
- Author(s)
  Shibata N, H Kurokawa, Y Doi, T Yagi, K Yamane, J Wachino, S Satowa, K Kimura, S Ishikawa, H Kato, Y Ozawa, K Shibayama, K Kai, F Konda, Y Arakawa.
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 50(2)
  
  Pages: 791-795
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Novel plasmid-mediated 16S rRNA methirase, RmtC, found in a proteus mirabilis isolate demonstrating extraordinary high-lebel resistance against various aminoglicosides.2006
- Author(s)
  Wachino J, K Yamane, S Suzuki, N Shibata, K Kimura, Y Arakawa
- Journal Title
  
  Antimicrob. Agents Chemoter. 50(1)
  
  Pages: 178-184
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Horizontal transfer of blaCMY-bearing plasmids among clinical Esherichia coil and Kiebsiella pneumoniae isolates and emergence of cefepime-hydroyzing CMY-19.2006
- Author(s)
  Wachino J, H Kurokawa, S Suzuki, K Yamane, N Shibata, K Kimura, Y Ike, Y Arakawa
- Journal Title
  
  Antimicrob. Agents Chemoter. 50(2)
  
  Pages: 534-541
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Novel plasmid-Mediated 16S rRNA Methilase, RmtC, found in a p roteus mirabilis isolate demonstrating extraordinary high-level resistance against various aminoglycosides.2006
- Author(s)
  Wachino J, K Yamane, K Shibayama, H Kurokawa, N Shibata, S Suzuki, Y Doi, K Kimura, Y Ike, Y Arakawa
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 50(1)
  
  Pages: 178-184
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Horizontal transfer of blaCMY-bearing plasmids among clinical Esherichia coli and Klebsiella pneumoniae isolates and emergence of cefepime-hydroyzing CMY-19.2006
- Author(s)
  Wachino J, H Kurokawa, S Suzuki, K Yamane, N Shibata, K Kimura, Y Ike, Y Arakawa
- Journal Title
  
  Antimicrob.Agents Chemoter. 50(2)
  
  Pages: 534-541
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Horizontal transfer of blaCMY-bearing plasmids among clinical Esherichia coli and Klebsiella phew noniae isolates and emergence of cefepime hydroyzing CMY-19.2006
- Author(s)
  Wachino J, H Kurokawa, S Suzuki, K Yamane, N Shibata, K Ki mura, Y Ike, Y Arakawa.
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 50(2)
  
  Pages: 534-541
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] PCR classification of CTX-M-type β-lactamase genes identified in clinically isolated gram-negative bacilli in Japan.2006
- Author(s)
  Shibata N, H Kurokawa, Y Doi, et al.
- Journal Title
  
  Antimicrob.Agents Chemoter. 50(2)
  
  Pages: 791-795
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] PCR classification of CTX-M-type β-lactamase genes identified in clinically isolated gram-negative bacilli in Japan.2006
- Author(s)
  Shibata N, H Kurokawa, Y Doi, et al.
- Journal Title
  
  Antimicrob. Agents Chemoter. 50(2)
  
  Pages: 791-795
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Novel plasmid-mediated 16S rRNA methirase, RmtC, found in a proteus mirabilis isolate demonstrating extraordinary high-lebel resistance against various aminoglicosides.2006
- Author(s)
  Wachino J, K Yamane, S Suzuki, N Shibata, K Kimura, Y Ike, Y Arakawa
- Journal Title
  
  Antimicrob.Agents Chemoter. 50(1)
  
  Pages: 178-184
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Practical Methods Using Boronbic acid Compounds for Identification of Class C beta Lactamase-Producing Klebsiella pneumoniae and Esherichia coli.2005
- Author(s)
  Yagi T, J Wachino, H Kurokawa, S Suzuki, K Yamane, Y Doi, N Shibata, H Kato, K Shibayama, Y Arakawa
- Journal Title
  
  Journal of Clinical Microbiology 43(6)
  
  Pages: 2551-2558
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Practical methods using boronic acid compounds for identification of class C beta-lactamases-producing Klebsiella pneumoniae and Esherichia coli.2005
- Author(s)
  Yago T, J Wachino, K Yamane, S Suzuki, K Doi, N Shibata, et al.
- Journal Title
  
  J Clin.Microbiology 43(6)
  
  Pages: 2551-2558
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Practical methods using boronic acid compounds for identification of class C beta-lactamases-producing Klebsiella pneumoniae and Esherichia coli.2005
- Author(s)
  Yago T, J Wachino, K Yamane, S Suzuki, K Doi, N Shibata, et al.
- Journal Title
  
  J Chin. Microbiology 43(6)
  
  Pages: 2551-2558
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Nosocomial Transmission of CTX-M-2 β-Lactamase-Producing Acinetobacter baumannii in a Neurosurgery Ward.2004
- Author(s)
  Noriyuki Nagano, Yukiko Nagano, Cristophie Cordevant, Naohiro Shibata, Yoshichika Arakawa
- Journal Title
  
  Journal of Clinical Microbiology 42巻9号
  
  Pages: 3978-3984
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Esherichia coli Producing CTX M-2 Beta Lactamase in Cattle, Japan.2004
- Author(s)
  Shiraki Y, N Shibata, Y Doi, Y Arakawa.
- Journal Title
  
  Emerg Infect Dis. 10(1)
  
  Pages: 69-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Metallo-beta-Lactamase-Producing Gram Negativer Bacilli : Labolatory-Based Surveillance in Cooperation with 13 Clinical Labolatories in the Kinki Region of Japan.2004
- Author(s)
  Hisaaki Nisio, Masaru Komatsu, Naohiro Shibata, Kouichi Shimakawa, Noriyuki Sueyoshi, Toshiro Orita, Tomomi Kofuku, Katsutoshi Yamasaki, Masako Sakamoto, Shohiro Kinoshita, Masanori Aihara, Yoshichika Arakawa
- Journal Title
  
  Journal of Clinical Microbiology 42巻11号
  
  Pages: 5256-5263
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] Eshericchia toll Producing CTX-M-2 beta Lactamase in Cattle, Japan.2004
- Author(s)
  Yutaka Shiraki, Naohiro Shibata, Yohei Doi, Yoshihika Arakawa
- Journal Title
  
  Emerging Infectious Diseases 10巻1号
  
  Pages: 69-75
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] PCR Typing of genetic Determinats for Metallo-Beta-Lactamases and Integrases Carried By Gram-Negative Bacteria Isolated In Japan, with Focus on the Class 3 Integron.2003
- Author(s)
  Shibata N, Y Doi, K Yamane, T Yagi, H Kurokawa, K Shibayama, H Kato, K Kai, Y Arakawa.
- Journal Title
  
  Journal of Clinical Microbiology 41(12)
  
  Pages: 5407-5413
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590470
[Journal Article] A New TEM-derived extended-spectrum beta-lactamase (TEM-91) with an R164C substitution at the omega-loop confers ceftazidime resistance.2003
- Author(s)
  Kurokawa H, N Shibata, Y Doi, K Shibayama, K Kamachi, T Yagi, Y Arakawa.
- Journal Title
  
  Antimicrobial Agents and Chemotherapy 47(9)
  
  Pages: 2981-2983
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590470
[Presentation] 耐性菌up date-進化するβ-ラクタマーゼ、最新知見と臨床的インパクト2008
- Author(s)
  柴田尚宏
- Organizer
  第82回日本感染症学会総会
- Year and Date
  2008-04-03
- Data Source
  KAKENHI-PROJECT-19590579
[Presentation] CTX-M-9型ESBL産生Salmonella enterica serotype Typhmuriumによる急性胃腸炎の1症例2008
- Author(s)
  常松範子, 柴田尚宏, 荒川宜親
- Organizer
  第19回日本臨床微生物学学会
- Place of Presentation
  東京
- Year and Date
  2008-01-26
- Data Source
  KAKENHI-PROJECT-19590579
[Presentation] 同一患者から3菌種のESBL産生菌が検出された症例についての検討2008
- Author(s)
  本間操, 柴田尚宏, 荒川宜親
- Organizer
  第19回日本臨床微生物学学会
- Place of Presentation
  東京
- Year and Date
  2008-01-26
- Data Source
  KAKENHI-PROJECT-19590579
[Presentation] 耐性菌 up date-進化するβ-ラクタマーゼ、最新知見と臨床的インパクト2008
- Author(s)
  柴田尚宏
- Organizer
  第82回日本感染症学会総会
- Place of Presentation
  さんらぼー島根
- Year and Date
  2008-04-03
- Data Source
  KAKENHI-PROJECT-19590579
[Presentation] Molecular characterization of both a novel Japan-type CTX-M-3 and IMP-1 b-Lactamase producing Enterobacter aerogenes in Japan.2007
- Author(s)
  Shibata N, S. Suzuki, K. Yamane, J. Wachino, K. Kimura, and Y. Arakawa.
- Organizer
  47th International Conference of Antimicrobial and Chemotherapy
- Place of Presentation
  Chicago,USA
- Year and Date
  2007-09-21
- Data Source
  KAKENHI-PROJECT-19590579
[Presentation] 我が国のグラム陰性桿菌におけるCTX-M-1型グループESBL遺伝子の保有状況と遺伝子周辺構造の解析2007
- Author(s)
  柴田尚宏, 鈴木里和, 山根一和, 荒川宜親
- Organizer
  第81回日本感染症学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19590579

1. ARAKAWA Yoshichika (10212622)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. SHIBAYAMA Keigo (50283437)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YAMANE Kunikazu (00356247)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SUZUKI Satowa (30373400)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. MORI Shigetarou (60425676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KIMURA Kouji (50425675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. WACHINO Jun-ichi (00535651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUI Mari (50555761)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIBATA Naohiro 柴田 尚宏

柴田 尚宏 シバタ ナオヒロ

Research Projects

Research Products

Co-Researchers

Molecular mechanism of accumulation and rearrangement of antibiotic resistance gene in bacteria.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Detection methods and survey of drug -resistance in Gram-Negative bacteria except Escherichia coli and Klebsiella spp.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

多剤耐性病原細菌における薬剤耐性遺伝子の集積および再配列機構に関する研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genetic typing and clinical method of detecting metallo-beta-lactamase-producers in gram-negative rods in JapanPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

グラム陰性桿菌におけるメタロ-β-ラクタマーゼおよび基質拡張型β-ラクタマーゼ遺伝子の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Change in the prevalence of extended-spectrum-beta-lactamase-producing Esherichia coli2009

Author(s)

Journal Title

Data Source

[Journal Article] Change in the prevalence of extended-spectrum-beta-lactamase-producing Esherichia coli in Japan by clonal spread.2009

Author(s)

Journal Title

Data Source

[Journal Article] カルバペネム耐性菌の検出法2008

Author(s)

Journal Title

Data Source

[Journal Article] First molecular characterization of group B streptcocci with reduced penicillin susceptibilit2008

Author(s)

Journal Title

Data Source

[Journal Article] First molecular characterization of group B streptcocci with reduced penicillin susceptibility.2008

Author(s)

Journal Title

Data Source

[Journal Article] MDRPの検出法2008

Author(s)

Journal Title

Data Source

[Journal Article] New Plasmid-Mediated Fluoroquinolone Efflux Pump,QepA,Found in an Escherichia coli Clinical Isolate.2007

Author(s)

Journal Title

Data Source

[Journal Article] Outbreak of CTX-M-3-type extended-spectrum β-lactamase-producing Enterobacter cloacae in a pediatric ward.2007

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Novel Plasmid-Mediated 16S rRNA m^1A1408 Methyltransferase,NpmA,Found in a Clinically Isolated Escherichia coli Strain Resistant to Structurally Diverse Aminoglycosides2007

Author(s)

Journal Title

Data Source

[Journal Article] PCR Classification of CTX-M-Type Beta-Lactamase Genes Identified in Clinically Isolated Gram-Negative Bacilli in Japan.2006

Author(s)

Journal Title

Description

Data Source

[Journal Article] Novel plasmid-mediated 16S rRNA methirase, RmtC, found in a proteus mirabilis isolate demonstrating extraordinary high-lebel resistance against various aminoglicosides.2006

Author(s)

Journal Title

SHIBATA Naohiro 柴田尚宏

柴田尚宏シバタナオヒロ