NOHARA Atsushi 野原淳

Researcher Number	50313648
Other IDs
External Links
Affiliation *help	2017 – 2018 : 金沢大学, 保健管理センター, 助教 2016 : 金沢大学, 医学系, 助教 2013 – 2015 : 金沢大学, 医薬保健学総合研究科, 特任准教授 2012 : 金沢大学, 医薬保健学総合研究科, 准教授 2011 : 金沢大学, 医学(系)研究科(研究院), 准教授 … More
Review Section/Research Field	Principal Investigator Metabolomics / Metabolomics Except Principal Investigator Cardiovascular medicine / Laboratory medicine
Keywords	Principal Investigator 冠動脈硬化症 / 核内受容体 / リポ蛋白リパーゼ / 糖尿病 / 動脈硬化症 / 低比重リポ蛋白 / Coronary artery disease / メタボリックシンドローム / コレステロールエステル転送蛋白 / 残余リスク … More Except Principal Investigator リポ蛋白リパーゼ / HTGL / 高比重リポ蛋白 / 内臓脂肪 / 低HDL / インスリン抵抗性 / 全エクソームシーケンス / メタボリックシンドローム / LPL / ANGPTL3 / sdLDL / 動脈硬化 / 肝性リパーゼ Less

ライソゾーム酸性リパーゼによる冠動脈疾患進展の機序解明と制御Principal InvestigatorOngoing
- Principal Investigator
  
  野原淳
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University
エクソームシーケンスを用いた新規高比重リポ蛋白代謝制御因子の発見とその機能解析Ongoing
- Principal Investigator
  
  川尻剛照
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kanazawa University
ANGPTL8 function and development of coronary artery diseasePrincipal Investigator
- Principal Investigator
  
  Nohara Atsushi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University
High-density lipoprotein composition and development of coronary artery diseasePrincipal Investigator
- Principal Investigator
  
  NOHARA Atsushi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University
Novel method of measuring activities of enzymes involved in lipid metabolism
- Principal Investigator
  
  KOBAYASHI Junji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kanazawa University
Regulation of Cardiovascular Risk Factors by Metabolism-associated Nuclear ReceptorsPrincipal Investigator
- Principal Investigator
  
  NOHARA Atsushi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University
代謝関連核内受容体遺伝子変異機能解析と肥満および脂質代謝異常Principal Investigator
- Principal Investigator
  
  野原淳
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University
核内受容体PPAR-α遺伝子変異体機能解析と脂質代謝異常Principal Investigator
- Principal Investigator
  
  野原淳
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kanazawa University

All 2017 2016 2015 2014 2013 2012 2011 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Lipid Management in a Japanese Community:Attainment Rate of Target Set by the Japan Atherosclerosis Society Guidelines for the Prevention of Atherosclerotic Cardiovascular Diseases 2012.2017
- Author(s)
  Tada H, Kawashiri MA, Nohara A, Inazu A, Kobayashi J, Yasuda K, Mabuchi H, Yamagishi M, Hayashi K.
- Journal Title
  
  J Atheroscler Thromb.
  
  Volume : 24 Issue : 3 Pages : 338-345
- Publisher
  Japan Atherosclerosis Society = 日本動脈硬化学会
- DOI
  10.5551/jat.36004
- Year and Date
  2017-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461359, KAKENHI-PROJECT-15K08627, KAKENHI-PROJECT-15K09118
[Journal Article] Impact of clinical signs and genetic diagnosis of familial hypercholesterolaemia on the prevalence of coronary artery disease in patients with severe hypercholesterolaemia2017
- Author(s)
  Tada H, Kawashiri MA, Nohara A, Inazu A, Mabuchi H, Yamagishi M.
- Journal Title
  
  European Heart Journal
  
  Volume : -
- DOI
  10.1093/eurheartj/ehx004
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-16K19394
[Journal Article] Prevalence, clinical features, and prognosis of patients with extremely low high-density lipoprotein cholesterol.2016
- Author(s)
  Tada H, Kawashiri MA, Konno T, Nohara A, Inazu A, Mabuchi H, Yamagishi M, Hayashi K.
- Journal Title
  
  J Clin Lipidol.
  
  Volume : 10 Pages : 1311-1317
- DOI
  10.1016/j.jacl.2016.08.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09118
[Journal Article] Minimal contribution of severe hypertriglyceridemia in L-asparaginase-associated pancreatitis developed in a child with acute lymphocytic leukemia.2016
- Author(s)
  Goto Y, Nishimura R, Nohara A, Mase S, Fujiki T, Irabu H, Kuroda R, Araki R, Ikawa Y, Maeba H, Yachie A.
- Journal Title
  
  Rinsho Ketsueki.
  
  Volume : 57 Pages : 994-8
- DOI
  10.11406/rinketsu.57.994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461359
[Journal Article] Efficacy and Safety of Alirocumab in Japanese Patients With Heterozygous Familial Hypercholesterolemia or at High Cardiovascular Risk With Hypercholesterolemia Not Adequately Controlled With Statins　- ODYSSEY JAPAN Randomized Controlled Trial.2016
- Author(s)
  Teramoto T, Kobayashi M, Tasaki H, Yagyu H, Higashikata T, Takagi Y, Uno K, Baccara-Dinet MT, Nohara A.
- Journal Title
  
  Circ J.
  
  Volume : 80 Pages : 1980-7
- DOI
  10.1253/circj.CJ-16-0387
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461359
[Journal Article] Lipoprotein(a) in Familial Hypercholesterolemia With Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Gain-of-Function Mutations.2016
- Author(s)
  Tada H, Kawashiri MA, Yoshida T, Teramoto R, Nohara A, Konno T, Inazu A, Mabuchi H, Yamagishi M, Hayashi K.
- Journal Title
  
  Circ J.
  
  Volume : 80 Issue : 2 Pages : 512-518
- Publisher
  Japanese Circulation Society = 日本循環器学会
- DOI
  10.1253/circj.CJ-15-0999
- Year and Date
  2016-01-25
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-26460670
[Journal Article] Changes in lipoprotein lipase and endothelial lipase mass in familial hypercholesterolemia during three-drug lipid-lowering combination therapy2016
- Author(s)
  Tada H, Kobayashi J, Kawashiri MA, Miyashita K, Nohara A, Inazu A, Nakajima K, Mabuchi H, Yamagishi M
- Journal Title
  
  Lipids Health Dis
  
  Volume : 15 Pages : 66
- Publisher
  BioMed Central
- DOI
  10.1186/s12944-016-0238-z
- Year and Date
  2016-04-02
- Language
  English
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08627, KAKENHI-PROJECT-26461359, KAKENHI-PROJECT-15K09118
[Journal Article] A de novo mutation of the LDL receptor gene as the cause of familial hypercholesterolemia identified using whole exome sequencing2016
- Author(s)
  Tada H, Hosomichi K, Okada H, Kawashiri MA, Nohara A, Inazu A, Tomizawa S, Tajima A, Mabuchi H, Hayashi K.
- Journal Title
  
  Clin Chim Acta
  
  Volume : 453 Pages : 194-196
- DOI
  10.1016/j.cca.2015.12.028
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-15H04320, KAKENHI-PROJECT-26893094
[Journal Article] A Rare Coincidence of Sitosterolemia and Familial Mediterranean Fever Identified by Whole Exome Sequencing.2016
- Author(s)
  Tada H, Kawashiri MA, Okada H, Endo S, Toyoshima Y, Konno T, Nohara A, Inazu A, Takao A, Mabuchi H, Yamagishi M, Hayashi K.
- Journal Title
  
  J Atheroscler Thromb.
  
  Volume : 23 Issue : 7 Pages : 884-890
- Publisher
  Japan Atherosclerosis Society = 日本動脈硬化学会
- DOI
  10.5551/jat.34827
- Year and Date
  2016-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09118
[Journal Article] Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation2015
- Author(s)
  Hayashi K, Konno T, Tada H, Tani S, Liu L, Fujino N, Nohara A, Hodatsu A, Tsuda T, Tanaka Y, Kawashiri MA, Ino H, Makita N, Yamagishi M.
- Journal Title
  
  Circ Arrhythm Electrophysiol
  
  Volume : 8 Pages : 1095-1104
- DOI
  10.1161/CIRCEP.114.002519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-26460670, KAKENHI-PROJECT-15K15311, KAKENHI-PROJECT-15H04823, KAKENHI-PROJECT-25460648, KAKENHI-PROJECT-25860589, KAKENHI-PROJECT-24390199
[Journal Article] Exome Sequencing in Suspected Monogenic Dyslipidemias2015
- Author(s)
  Stitziel NO, Peloso GM, Abifadel M, Cefalu AB, Fouchier S, Motazacker MM, Tada H, Larach DB, Awan Z, Haller JF, Pullinger CR, Varret M, Noto D, Tarugi P, Kawashiri MA, Nohara A, Yamagishi M, Kathiresan S. et al.
- Journal Title
  
  Circulation: Cardiovascular Genetics
  
  Volume : 8 Pages : 343-50
- DOI
  10.1161/CIRCGENETICS.114.000776
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591041, KAKENHI-PROJECT-26893094, KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-26461359
[Journal Article] Infantile Cases of Sitosterolaemia with Novel Mutations in the ABCG5 Gene: Extreme Hypercholesterolaemia is Exacerbated by Breastfeeding.2015
- Author(s)
  Tada H, Kawashiri MA, Takata M, Matsunami K, Imamura A, Matsuyama M, Sawada H, Nunoi H, Konno T, Hayashi K, Nohara A, Inazu A, Kobayashi J, Mabuchi H, Yamagishi M.
- Journal Title
  
  JIMD Rep.
  
  Volume : in press Pages : 115-122
- DOI
  10.1007/8904_2014_404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591041, KAKENHI-PROJECT-15K09118
[Journal Article] Extreme Contrast of Postprandial Remnant-Like Particles Formed in Abetalipoproteinemia and Homozygous Familial Hypobetalipoproteinemia2015
- Author(s)
  Kawashiri MA, Tada H, Hashimoto M, Taniyama M, Nakano T, Nakajima K, Inoue T, Mori M, Nakanishi C, Konno T, Hayashi K, Nohara A, Inazu A, Koizumi J, Ishihara H, Kobayashi J, Hirano T, Mabuchi H, Yamagishi M.
- Journal Title
  
  JIMD Rep
  
  Volume : in press Pages : 85-94
- DOI
  10.1007/8904_2015_415
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591041, KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-26461359
[Journal Article] Whole exome sequencing combined with integrated variant annotation prediction identifies asymptomatic Tangier disease with compound heterozygous mutations in ABCA1 gene2015
- Author(s)
  Tada H, Kawashiri MA, Nohara A, Saito R, Tanaka Y, Nomura A, Konno T, Sakata K, Fujino N, Takamura T, Inazu A, Mabuchi H, Yamagishi M, Hayashi K.
- Journal Title
  
  Atherosclerosis
  
  Volume : 240 Pages : 324-9
- DOI
  10.1016/j.atherosclerosis.2015.04.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591041, KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-26461329
[Journal Article] Characterization of Autosomal Dominant Hypercholesterolemia Caused by PCSK9 Gain of Function Mutations and Its Specific Treatment With Alirocumab, a PCSK9 Monoclonal Antibody2015
- Author(s)
  Hopkins PN, Defesche J, Fouchier SW, Yagi K, Krempf M, Swergold GD et. al.
- Journal Title
  
  Circ Cardiovasc Genet.
  
  Volume : 8 Pages : 823-831
- DOI
  10.1161/CIRCGENETICS.115.001129
- Peer Reviewed / Int'l Joint Research / Open Access
- Data Source
  KAKENHI-PROJECT-15K08544, KAKENHI-PROJECT-15K09118, KAKENHI-PROJECT-26461359
[Journal Article] Clinical characteristics of Japanese patients with severe hypertriglyceridemia.2015
- Author(s)
  Tada H, Kawashiri MA, Nakahashi T, Yagi K, Chujo D, Ohbatake A, Mori Y, Mori S, Kometani M, Fujii H, Nohara A, Inazu A, Mabuchi H, Yamagishi M, Hayashi K.
- Journal Title
  
  J Clin Lipidol.
  
  Volume : 9 Pages : 519-524
- DOI
  10.1016/j.jacl.2015.05.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08544, KAKENHI-PROJECT-15K09118
[Journal Article] Impact of Serum Retinol-Binding Protein 4 Levels on Regulation of Remnant-Like Particles Triglyceride in Type 2 Diabetes Mellitus2015
- Author(s)
  Yamaaki N, Yagi K, Kobayashi J, Nohara A, Ito N, Asano A, Nakano K, Liu J, Okamoto T, Mori Y, Ohbatake A, Okazaki S, Takeda Y, Yamagishi M
- Journal Title
  
  J Diabetes Res
  
  Volume : 2013 Pages : 143515
- Publisher
  Hindawi Publishing Corporation
- DOI
  10.1155/2013/143515
- Year and Date
  2015-03-23
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590663, KAKENHI-PROJECT-23591334
[Journal Article] Epicardial Adipose Tissue as a Predictor of Plaque Vulnerability in Patients With Mild Chronic Kidney Disease2015
- Author(s)
  Nohara A.
- Journal Title
  
  Circ J.
  
  Volume : 80 Pages : 64-6
- DOI
  10.1253/circj.CJ-15-1265
- Data Source
  KAKENHI-PROJECT-26461359
[Journal Article] Therapy: PCSK9 inhibitors for treating familial hypercholesterolaemia2015
- Author(s)
  Mabuchi H, Nohara A.
- Journal Title
  
  Nat Rev Endocrinol
  
  Volume : 11 Pages : 8-9
- DOI
  10.1038/nrendo.2014.205
- Data Source
  KAKENHI-PROJECT-26461359
[Journal Article] Clinical significance of measuring soluble LR11, a circulating marker of atherosclerosis and HbA1c in familial hypercholesterolemia2014
- Author(s)
  Nohara A, Kobayashi J, Kawashiri M-A, Tada H, Inazu A, Jiang M, Mabuchi H, Bujo H.
- Journal Title
  
  Clinical Biochemistry
  
  Volume : in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591334
[Journal Article] Clinical significance of measuring soluble LR11, a circulating marker of atherosclerosis and HbA1c in familial hypercholesterolemia2014
- Author(s)
  Nohara A, Kobayashi J , Kawashiri MA, Tada H, Inazu A, Jiang M, Mabuchi H, Bujo H
- Journal Title
  
  Clin Biochem
  
  Volume : 47 Pages : 1326-1328
- DOI
  10.1016/j.clinbiochem.2014.05.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590663, KAKENHI-PROJECT-23591334, KAKENHI-PROJECT-26461359
[Journal Article] Genotypic and phenotypic features in homozygous familial hypercholesterolemia caused by proprotein convertase subtilisin/kexin type 9（PCSK9）gain-of-function mutation.2014
- Author(s)
  Mabuchi H, Nohara A, Noguchi T, Kobayashi J, Kawashiri MA, Inoue T, Mori M, Tada H, Nakanishi C, Yagi K, Yamagishi M, Ueda K, Takegoshi T, Miyamoto S, Inazu A, Koizumi J; The Hokuriku FH Study Group
- Journal Title
  
  Atherosclerosis.
  
  Volume : 236 Pages : 54-61
- DOI
  10.1016/j.atherosclerosis.2014.06.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590663, KAKENHI-PROJECT-24591041, KAKENHI-PROJECT-26461359
[Journal Article] MTP inhibitor for treating severe LDL cholesterolemia2013
- Author(s)
  Mabuchi H, Nohara A
- Journal Title
  
  Clinical Lipidology
  
  Volume : 8(4) Pages : 387-389
- URL
  http://www.futuremedicine.com
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591334
[Journal Article] Effects of coenzyme Q(10) on LDL oxidation in vitro2013
- Author(s)
  Ahmadvand H, Mabuchi H, Nohara A, Kobayahi J, Kawashiri MA
- Journal Title
  
  Acta Med Iran
  
  Volume : 51(1) Pages : 12-8
- URL
  http://acta.tums.ac.ir
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591334
[Journal Article] Novel mutations of cholesteryl ester transfer protein(CETP) gene in Japanese hyperalphalipoproteinemic subjects2012
- Author(s)
  Ohtani R, Inazu A, Noji Y, Wakasugi T, Miwa K, Tada H, Kawashiri MA, Noguchi T, Nohara A, Kobayashi J, Koizumi J, Yamagishi M, Mabuchi H
- Journal Title
  
  Clin Chim Acta
  
  Volume : 413 Issue : 5-6 Pages : 537-543
- Publisher
  Elsevier BV
- DOI
  10.1016/j.cca.2011.11.010
- Year and Date
  2012-03-22
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591160, KAKENHI-PROJECT-23590663, KAKENHI-PROJECT-23591334
[Journal Article] A novel type of familial hypercholesterolemia: double heterozygous mutations in LDL receptor and LDL receptor adaptor protein 1 gene.2012
- Author(s)
  Tada H, Kawashiri MA, Ohtani R, Noguchi T, Nakanishi C, Konno T, Hayashi K, Nohara A, Inazu A, Kobayashi J, Mabuchi H, Yamagishi M.
- Journal Title
  
  Atherosclerosis
  
  Volume : 42 Issue : 2 Pages : 1094-9
- Publisher
  Elsevier
- DOI
  10.1016/j.atherosclerosis.2011.08.004
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591041, KAKENHI-PROJECT-21591160, KAKENHI-PROJECT-23590663, KAKENHI-PROJECT-23591334
[Journal Article] Post-prandial remnant lipoprotein metabolism in autosomal recessive hypercholesterolaemia.2012
- Author(s)
  Tada H
- Journal Title
  
  Eur J Clin Invest.
  
  Volume : 42 Pages : 1094-1099
- DOI
  10.1111/j.1365-2362.2012.02700.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590517, KAKENHI-PROJECT-23590663, KAKENHI-PROJECT-23591334, KAKENHI-PROJECT-24790748
[Journal Article] Efficacy and Safety of Coadministration of Rosuvastatin, Ezetimibe, and2012
- Author(s)
  Kawashiri MA, Nohara A, Noguchi T, Tada H, Nakanishi C, Mori M, Konno T, Hayashi K, Fujino N, Inazu A, Kobayashi J, Mabuchi H, Yamagishi M
- Journal Title
  
  Am J Cardiol
  
  Volume : 109 Pages : 364-9
- DOI
  10.1016/j.amjcard.2011.09.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591160, KAKENHI-PROJECT-22590808, KAKENHI-PROJECT-23590663, KAKENHI-PROJECT-23591334
[Journal Article] Altered Metabolism of Low-density Lipoprotein and Very Low-density Lipoprotein Remnant in Autosomal Recessive Hypercholesterolemia: Results from Stable Isotope Kinetic Study in vivo.2012
- Author(s)
  Tada H, Kawashiri MA, Ikewaki K, Terao Y, Noguchi T, Nakanishi C, Tsuchida M, Takata M, Miwa K, Konno T, Hayashi K, Nohara A, Inazu A, Kobayashi J, Mabuchi H, Yamagishi M
- Journal Title
  
  Circ Cardiovasc Genet
  
  Volume : 5 Pages : 35-41
- DOI
  10.1161/CIRCGENETICS.111.960948
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591160, KAKENHI-PROJECT-23590663, KAKENHI-PROJECT-23591334
[Journal Article] Comparison of effects of bezafibrate and fenofibrate on circulating proprotein convertase subtilisin/kexin type 9 and adipocytokine levels in dyslipidemic subjects with impaired glucose tolerance or type 2 diabetes mellitus : results from a crossover study2011
- Author(s)
  Noguchi T, et al., 計14名、9番目
- Journal Title
  
  Atherosclerosis
  
  Volume : 217 Issue : 1 Pages : 165-170
- Publisher
  Elsevier Ireland Ltd
- DOI
  10.1016/j.atherosclerosis.2011.02.012
- Year and Date
  2011-07-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591160, KAKENHI-PROJECT-22590772, KAKENHI-PROJECT-23590663, KAKENHI-PROJECT-23591334
[Journal Article] Cholesterol efflux from J774 macrophages and Fu5AH hepatoma cells to serum is preserved in CETP-deficient patients2009
- Author(s)
  Kenji Miwa, Akihiro Inazu, Masa-aki Kawashiri, Atsushi Nohara(他2名)
- Journal Title
  
  Clin Chim Acta 402(1-2)
  
  Pages : 19-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] A novel method for determining functional LDL receptor activity in familial hypercholesterolemia : application of the CD3/CD28 assay in lymphocytes2009
- Author(s)
  Hayato Tada, Masa-aki Kawashiri, Tohru Noguchi, Mika Mori, Masayuki Tsuchida, Mutsuko Takata, Atsushi Nohara(他5名)
- Journal Title
  
  Clin Chim Acta 400(1-2)
  
  Pages : 42-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] Apolipoprotein B gene mutations and fatty liver in Japanese hypobetalipoproteinemia2009
- Author(s)
  Shoji Katsuda, Masa-aki Kawashiri, Akihiro Inazu, Hayato Tada, Masayuki Tsuchida, Yoshibumi Kaneko, Tsuyoshi Nozue, Atsushi Nohara(他5名)
- Journal Title
  
  Clin Chim Acta 399(1-2)
  
  Pages : 64-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] Retinoid X Receptor Heterodimer Variants and Cardiovascular Risk Factors2009
- Author(s)
  Atsushi Nohara
- Journal Title
  
  J Atheroscler Thromb (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] Cholesterol efflux from J774 macrophages and Fu5AH hepatoma cells to serum is preserved in CETP-deficient patients.2009
- Author(s)
  Kenji Miwa
- Journal Title
  
  Clin Chim Acta 402
  
  Pages : 19-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] Apolipoprotein B gene mutations and fatty liver in Japanese hypobetalipoproteinemia.2009
- Author(s)
  Shoji Katsuda
- Journal Title
  
  Clin Chim Acta 399
  
  Pages : 64-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] A novel method for determining funct ional LDL receptor activity in fami 1ial hypercholesterolemia : applicat ion of the CD3/CD28 assay in lymphocytes2009
- Author(s)
  Hayato Tada
- Journal Title
  
  Clin Chim Acta 400
  
  Pages : 42-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] Effects of CoQ10 supplementation on plasma lipoprotein lipid, CoQ10 and liver and muscle enzyme levels in hypercholesterolemic patients treated with atorvastatin:a randomized double-blind study2007
- Author(s)
  Hiroshi Mabuchi
- Journal Title
  
  Atherosclerosis 195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] Serum lipoprotein lipase mass:clinical significance of its measurement2007
- Author(s)
  Junji Kobayashi
- Journal Title
  
  Clin Chim Acta 378
  
  Pages : 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] High frequency of a retinoid X receptor gamma gene variant in familial combined hyperlipidemia that associates with atherogenic dyslipidemia2007
- Author(s)
  Atsushi Nohara
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 27
  
  Pages : 923-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] The relationship of serum lipoprotein lipase mass with fasting serum a polipoprotein B-48 and remnant-like particle triglycerides in type 2 diabetic patients2007
- Author(s)
  Junji Kobayashi
- Journal Title
  
  Horm Metab Res. 39
  
  Pages : 612-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] The relationship of serum lipoprotein lipase mass with fasting serum apolipoprotein B-48 and remnant-like particle triglycerides in type 2 diabetic patients2007
- Author(s)
  Junji Kobayashi, Katsuyuki Nakajima, Atsushi Nohara(他6名)
- Journal Title
  
  Horm Metab Res 39(8)
  
  Pages : 612-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] High frequency of a retinoid X receptor gamma gene variant in familial combined hyperlipidemia that associates with atherogenic dyslipidemia2007
- Author(s)
  Atsushi Nohara(他13名)
- Journal Title
  
  Arterioscler Thromb Vasc Biol 27(4)
  
  Pages : 923-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] Serum lipoprotein lipase mass : clinical significance of its measurement2007
- Author(s)
  Junji Kobayashi, Atsushi Nohara(他5名)
- Journal Title
  
  Clin Chim Acta 378(1-2)
  
  Pages : 7-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] Effects of CoQ10 supplementation on plasma lipoprotein lipid, CoQ10 and liver and muscle enzyme levels in hypercholesterolemic patients treated with atorvastatin : a randomized double-blind study2007
- Author(s)
  Hiroshi Mabuchi, Atsushi Nohara(他5名)
- Journal Title
  
  Atherosclerosis 195(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Journal Article] Serum lipoprotein lipase mass : clinical significance of its measurement.2007
- Author(s)
  Junji Kobayashi
- Journal Title
  
  Clin Chim Acta 378(1-2)
  
  Pages : 7-12
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] High frequency of a retinoid X receptor gamma gene variant in familial combined hyperlipidemia that associates with atherogenic dyslipidemia.2007
- Author(s)
  Atsushi Nohara
- Journal Title
  
  Arterioscler Thromb Vasc Biol 27(4)
  
  Pages : 923-928
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] Effects of fenofibrate therapy on plasma ubiquinol-10 and ubiquinone-10 levels in Japanese patients with hyperlipidemia and type 2 diabetes mellitus.2006
- Author(s)
  Akimichi Asano
- Journal Title
  
  Pharmacotherapy. 26(4)
  
  Pages : 447-451
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] CETP (cholesteryl ester transfer protein) promoter -1337 C>T polymorphism protects against coronary atherosclerosis in Japanese patients with heterozygous familial hypercholesterolaemia.2006
- Author(s)
  Mutsuko Takata
- Journal Title
  
  Clin Sci 111(5)
  
  Pages : 325-331
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] The distribution of fasting and non-fasting serum triglyceride levels in Japanese population2006
- Author(s)
  Junji Kobayashi
- Journal Title
  
  Clin Chim Acta 374(1-2)
  
  Pages : 173-175
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] The relationship of percent body fat by bioelectrical impedance analysis with blood pressure, and glucose and lipid parameters.2006
- Author(s)
  Junji Kobayashi
- Journal Title
  
  J Atheroscler Thromb 13(5)
  
  Pages : 221-226
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] Long-term course of lipoprotein lipase (LPL) deficiency due to homozygous LPL(Arita) in a patient with recurrent pancreatitis, retained glucose tolerance, and atherosclerosis2005
- Author(s)
  Kawashiri M
- Journal Title
  
  J Clin Endocrinol Metab 90(12)
  
  Pages : 6541-6544
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] Association of coronary artery ectasia with plasma insulin levels in Japanese men of heterozygous familial hypercholesterolemia with the low-density lipoprotein receptor gene mutation K790X.2005
- Author(s)
  Murase Y
- Journal Title
  
  Clin Chim Acta 355(1-2)
  
  Pages : 33-39
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] RXRg Gene Variant is Associate with Lower HDL, Lower Lipoprotein Lipase, Advanced Coronary Artery Disease, and More Frequent in Familial Combined Hyperlipidemia2005
- Author(s)
  Nohara A
- Journal Title
  
  Circulation (Supplement) 112(17)
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] ATP-binding cassette transporter G8 M429V polymorphism as a novel genetic marker of higher cholesterol absorption in hypercholesterolaemic Japanese subjects.2005
- Author(s)
  Miwa K
- Journal Title
  
  Clin Sci 109(2)
  
  Pages : 183-188
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] Reduction of serum ubiquinol-10 and ubiquinone-10 levels by atorvastatin in hypercholesterolemic patients.2005
- Author(s)
  Mabuchi H
- Journal Title
  
  J Atheroscler Thromb 12(2)
  
  Pages : 111-119
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] Relationship of lipoprotein lipase and hepatic triacylglycerol lipase activity to serum adiponectin levels in Japanese hyperlipidemic men.2005
- Author(s)
  Kobayashi J
- Journal Title
  
  Horm Metab Res. 37(8)
  
  Pages : 505-509
- Data Source
  KAKENHI-PROJECT-17790603
[Journal Article] Retinoid X Receptor Heterodimer Variants and Cardiovascular Risk Factors
- Author(s)
  Atsushi Nohara, (他2名)
- Journal Title
  
  J Atheroscler Thromb (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] Impact of evolocumab, a PCSK9 inhibitor, withdrawing from regular LDL-apheresis therapy in patients with heterozygous familial hypercholesterolemia2017
- Author(s)
  Masaaki Kawashiri, Toshinori Higashikata, Atsushi Nohara, Chiaki Nakanishi, Hayato Tada, Hirofumi Okada, Masakazu Yamagishi
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K09118
[Presentation] Clinical Characteristics of Common PCSK9 Gain-of-Function E32K Variant with Higher TG Elevation, and Double Heterozygotes with Common PCSK9 Variants and LDLR mutations2016
- Author(s)
  Nohara A, Kawashiri M-A, Tada H, Yoshida M, Mori M, Nakanishi C, Yagi K, Inazu A, Yamaghishi M, Mabuchi H.
- Organizer
  84th European Atherosclerosis Society Congress 2016
- Place of Presentation
  Innsbruck
- Year and Date
  2016-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461359
[Presentation] Clinical Characteristics of Double Heterozygotes With PCSK9 Gain-of-Function Mutations and LDLR Mutations2016
- Author(s)
  Nohara A, Kawashiri M-A, Tada H, Yoshida M, Mori M, Nakanishi C, Yagi K, Inazu A, Yamaghishi M, Mabuchi H.
- Organizer
  American Heart Association Scientific Sessions 2016
- Place of Presentation
  New Orleans
- Year and Date
  2016-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461359
[Presentation] Impact of Betatrophin (ANGPTL8) R59W Mutation For Future Diabetes2015
- Author(s)
  Nohara A, Kawashiri M,Hattori H, Iwasaki T, Liu J, Yagi K, Yoshida M, Tada H, Mori M, Nakanishi C, Inazu A, Kobayashi A, Yamagishi M, Mabuchi M.
- Organizer
  American Heart Association Scientific Sessions 2015
- Place of Presentation
  米国　オーランド
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461359
[Presentation] A patient with compound heterozygous familial hypercholesterolemia accompanied with supravalvular aortic stenosis detected by Whole Exome Sequencing2015
- Author(s)
  川尻剛照、多田隼人、井上健、中西千明、森三佳、野原淳、稲津明広、馬渕宏、山岸正和
- Organizer
  第47回日本動脈硬化学会総会・学術集会
- Place of Presentation
  仙台
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-15K09118
[Presentation] Genetic CETP Deficiency Associated With Lower Coronary Stenosis Index in Dyslipdemic Patients in Japan2014
- Author(s)
  Nohara A, Yoshida M, Okazaki S, Inoue T, Mori M, Nakanishi C, Kawashiri M-A, Yagi K, Inazu A, Yamagishi M, Mabuchi H.
- Organizer
  The 82nd Congress of the European Atherosclerosis Society
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Common PCSK9 E32K Variant as Genetic Background of Familial Combined Hyperlipidemia2013
- Author(s)
  Nohara A, Noguchi T, Inoue T, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Inazu A, Yamagishi M, Mabuchi H
- Organizer
  The 81st European Atherosclerosis Society Congress
- Place of Presentation
  Lyon, France
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Common PCSK9 E32K Variant as Genetic Background of Familial Combined Hyperlipidemia.2013
- Author(s)
  Nohara A, Noguchi T, Inoue T, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Inazu A, Yamagishi M, Mabuchi H.
- Organizer
  The 81st European Atherosclerosis Society Congress
- Place of Presentation
  Lyon, France
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] シンポジウム３：日本における原発性高脂血症の現状　家族性高コレステロール血症の診断および治療の課題.2013
- Author(s)
  野原淳
- Organizer
  第45回日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京・京王プラザ
- Invited
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Usefulness of FH Gene Test in Patients with Dyslipidemia.2013
- Author(s)
  Nohara A, Ohtani R, Noguchi T, Inoue T, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Inazu A, Yamagishi M, Mabuchi H.
- Organizer
  第45回日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京・京王プラザ
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] シンポジウム3:日本における原発性高脂血症の現状家族性高コレステロール血症の診断および治療の課題2013
- Author(s)
  野原淳
- Organizer
  第45回日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Usefulness of FH Gene Test in Patients with Dyslipidemia2013
- Author(s)
  Nohara A, Ohtani R, Noguchi T, Inoue T, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Inazu A, Yamagishi M, Mabuchi H
- Organizer
  第45回日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Common PCSK9 E32K Variant as Genetic Background of Familial Combined Hyperlipidemia2013
- Author(s)
  Nohara A, Noguchi T, Inoue T, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Inazu A, Yamagishi M, Mabuchi H
- Organizer
  第77回日本循環器学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Impact of ER-Stress Affecting Variant of XBP-1 Gene on Lipids, Diabetes, Chronic Kidney Disease, and Coronary Artery Disease2012
- Author(s)
  Nohara A, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Inazu A, Kobayashi J, Yamagishi M, Mabuchi H
- Organizer
  American Heart Association's Scientific Sessions, 2012
- Place of Presentation
  Los Angeles (USA)
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Impact of “Isolated” and “Non-isolated” Low Levels of HDL-C2012
- Author(s)
  Nohara A, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Inazu A, Kobayashi J, Yamagishi M, Mabuchi H.
- Organizer
  第44回日本動脈硬化学会総会・学術集会
- Place of Presentation
  ヒルトン福岡シーホーク，福岡県
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Triglyceride-Rich High-Density Lipoprotein Composition as Residual Risk Biomarker of Coronary Artery Disease Including Reduced eGFR and Pre-diabetes.2012
- Author(s)
  Nohara A, Inazu A, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Kobayashi J, Yamagishi M, Mabuchi H.
- Organizer
  American Heart Association's Scientific Sessions, 2012
- Place of Presentation
  Los Angeles Convention Center, Los Angeles (USA)
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Impact of ER-Stress Affecting Variant of XBP-1 Gene on Lipids, Diabetes, Chronic Kidney Disease, and Coronary Artery Disease.2012
- Author(s)
  Nohara A, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Inazu A, Kobayashi J, Yamagishi M, Mabuchi H.
- Organizer
  American Heart Association's Scientific Sessions, 2012
- Place of Presentation
  Los Angeles Convention Center, Los Angeles (USA)
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Triglyceride-Rich High-Density Lipoprotein Composition as Residual Risk Biomarker of Coronary Artery Disease Including Reduced eGFR and Pre-diabetes2012
- Author(s)
  Nohara A, Inazu A, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Kobayashi J, Yamagishi M, Mabuchi H
- Organizer
  American Heart Association's Scientific Sessions
- Place of Presentation
  Los Angeles (USA)
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] HDL-C Was Negatively Associated with Achilles' Tendon Thickening among Genetically Confirmed Familial Hypercholesterolemia2012
- Author(s)
  Nohara A, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Inazu A, Kobayashi J, Yamagishi M, Mabuchi H
- Organizer
  HDL Satellite Symposium 2012
- Place of Presentation
  Cairns, AUS
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Hypertriglyceridemia eliminates positive correlations of plasma CETP with LDL-C and with Lp(a)2012
- Author(s)
  Nohara A, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri MA, Yagi K, Inazu A, Kobayashi J, Yamagishi M, Mabuchi H
- Organizer
  XVI International Symposium on Atherosclerosis 2012
- Place of Presentation
  Sydney, AUS
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Normalizing Pre-β1-HDL Levels with Eicosapentaenoic Acid Add-on to Atorvastatin2012
- Author(s)
  Nohara A, Kobayashi J, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri M, Yagi K, Inazu A, Yamagishi M, Mabuchi H
- Organizer
  第76回日本循環器学会総会・学術集会
- Place of Presentation
  福岡国際会議場(福岡)
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Hypertriglyceridemia eliminates positive correlations of plasma CETP with LDL-C and with Lp(a)2012
- Author(s)
  Nohara A, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri M, Yagi K, Inazu A, Kobayashi J, Yamagishi M, Mabuchi H
- Organizer
  XVI International Symposium on Atherosclerosis
- Place of Presentation
  Sydney Convention and Exhibition Centre (Australia)
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] シンポジウム・我が国に於ける家族性高コレステロール血症我が国に於けるFHの疫学とCHDへのリスク2011
- Author(s)
  野原淳,野口徹,小林淳二,多田隼人,森三佳,中西千明,川尻剛照,八木邦公,稲津明広,山岸正和,馬渕宏
- Organizer
  第43回日本動脈硬化学会総会・学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] シンポジウム・心血管疾患予防のための新しいバイオマーカーImpact of Triglyceride-Rich High-Density Lipoprotein Composition as a New Marker for Development of Angiographic Coronary Artery Disease2011
- Author(s)
  Nohara A, Inazu A, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri M, Yagi K, Kobayashi J, Yamagishi M, Mabuchi H
- Organizer
  第75回日本循環器学会総会・学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] シンポジウム・心血管疾患予防のための新しいバイオマーカー　Impact of Triglyceride-Rich High-Density Lipoprotein Composition as a New Marker for Development of Angiographic Coronary Artery Disease2011
- Author(s)
  Nohara A, Inazu A, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri M, Yagi K, Kobayashi J, Yamagishi M, Mabuchi H
- Organizer
  第75回日本循環器学会総会・学術集会
- Place of Presentation
  パシフィコ横浜(横浜)
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] "Intra-Individual Variability" of Fasting Lipids in Primary Hyperlipidemia is Associated With Fatty Liver, Hyperapobetalipoproteinemia and Advanced Coronary Artery Disease, But Not With Insulin Resistance2011
- Author(s)
  Nohara A, Yagi K, Noguchi T, Tada H, Mori M, Nakanishi C, Kawashiri M, Inazu A, Kobayashi J, Yamagishi M, Mabuchi H
- Organizer
  American Diabetes Association 71st Scientific Sessions
- Place of Presentation
  San Diego Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23591334
[Presentation] Maximum Lipid-lowering Therapy for Famal Hypercholesterolemia:Efficacy and Safety with High-dose Statin, Resin and Ezetimibe2008
- Author(s)
  野原淳
- Organizer
  第72回日本循環器学会総会・学術集会
- Place of Presentation
  福岡
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] RXRヘテロダイマー形成核内受容体多型と脂質・糖質代謝異常2008
- Author(s)
  野原淳
- Organizer
  第40回日本動脈硬化学会総会
- Place of Presentation
  つくば
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] Impact of Upstream Transcription Factor 1 Gene Variant on Genetically Confirmed Familial Hypercholesterolemia (K790X)2008
- Author(s)
  Atsushi Nohara
- Organizer
  81st American Heart Association 2008 Scientific Sessions
- Place of Presentation
  New Orleans, USA
- Year and Date
  2008-11-11
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] Maximum Lipid-lowering Therapy for Familial Hypercholesterolemia : Efficacy and Safety with High-dose Statin, Resin and Ezetimibe2008
- Author(s)
  野原淳
- Organizer
  第72回日本循環器学会総会・学術集会
- Place of Presentation
  福岡
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] RXRヘテロタイマー形成核内受容体多型と脂質・糖質代謝異常2008
- Author(s)
  野原淳
- Organizer
  第40回日本動脈硬化学会総会
- Place of Presentation
  つくば
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] Impact of Upstream Transcription Factor 1 Gene Varianton Genetically Confirmed Familial Hypercholesterolemia (K790X)2008
- Author(s)
  Atsushi Nohara
- Organizer
  81st American Heart Association 2008 Scientific Sessions
- Place of Presentation
  New Orleans, USA
- Year and Date
  2008-11-11
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] RXRヘテロダイマ-形成核内受容体多型と脂質低下療法2007
- Author(s)
  野原淳
- Organizer
  第39回日本動脈硬化学会総会・学術集会
- Place of Presentation
  大阪
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] Impact of common variant of bile acid receptor FXR gene on cardiovascular risk facotrs2007
- Author(s)
  Atsushi Nohara
- Organizer
  XVI International Symposium on Drugs AffectingL ipid Metabolism
- Place of Presentation
  New York, USA
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] Nuclear bile acid receptor gene variant improves efficacy of lipid-lowering therapy2007
- Author(s)
  Atsushi Nohara
- Organizer
  Arteriosclerosis, Thrombosis and Vascular Biology Annual Conference 2007
- Place of Presentation
  Chicago, USA
- Year and Date
  2007-04-19
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] Nuclear bile acid receptor gene variant improves efficacy of lipid-lowering therapy Arteriosclerosis2007
- Author(s)
  Atsushi Nohara
- Organizer
  Thrombosis and Vascular Biology Annual Conference 2007
- Place of Presentation
  Chicago, USA
- Year and Date
  2007-04-19
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] RXRヘテロダイマー形成核内受容体多型と脂質低下療法2007
- Author(s)
  野原淳
- Organizer
  第39回日本動脈硬化学会総会・学術集会
- Place of Presentation
  大阪
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] Impact of common variant of bile acid receptor FXR gene on cardiovascular risk facotrs2007
- Author(s)
  Atsushi Nohara
- Organizer
  XVI International Symposiumon Drugs Affecting Lipid Metabolism
- Place of Presentation
  New York, USA
- Year and Date
  2007-10-05
- Data Source
  KAKENHI-PROJECT-19591040
[Presentation] Impact of Loss of Function Variant of Betatrophin on Advanced Coronary Artery Disease Among Diabetic Patients in Japan
- Author(s)
  Nohara A, Yagi K, Liu J, Ohbatake A, Okazaki S, Yoshida M, Mori M, Nakanishi C, Tada H, Kawashiri M-A, Inazu A, Yamaghishi M, Mabuchi H.
- Organizer
  82nd European Atherosclerosis Society Congress
- Place of Presentation
  Madrid, Spain
- Year and Date
  2014-05-31 – 2014-06-03
- Data Source
  KAKENHI-PROJECT-26461359
[Presentation] Genetic CETP Deficiency Associated With Higher eGFR and Lower Coronary Stenosis Index in Dyslipdemic Patients in Japan
- Author(s)
  Nohara A, Inazu A, Okazaki S, Yoshida M, Mori M, Nakanishi C, Tada H, Kawashiri M-A, Yagi K, Yamaghishi M, Mabuchi H.
- Organizer
  American Heart Association Scientific Sessions 2014
- Place of Presentation
  Chicago, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26461359
[Presentation] Metabolic Burden Switches Impact of Betatrophin (ANGPTL8) R59W Mutation From Atheroprotective to Atherogenic Lipid Profiles
- Author(s)
  Nohara A, Yagi K, Liu J, Ohbatake A, Okazaki S, Yoshida M, Mori M, Nakanishi C, Tada H, Kawashiri M-A, Inazu A, Yamaghishi M, Mabuchi H.
- Organizer
  American Heart Association Scientific Sessions 2014
- Place of Presentation
  Chicago, USA
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26461359

1. KOBAYASHI Junji (60302577)

# of Collaborated Projects : 2results

# of Collaborated Products : 25results
2. INAZU Akihiro (80293348)

# of Collaborated Projects : 2results

# of Collaborated Products : 37results
3. YAGI Kunimasa (30293343)

# of Collaborated Projects : 2results

# of Collaborated Products : 30results
4. NOGUCHI Tohru (40456421)

# of Collaborated Projects : 1results

# of Collaborated Products : 25results
5. OKAZAKI Satoko (80613744)

# of Collaborated Projects : 1results

# of Collaborated Products : 3results
6. 川尻剛照 (90345637)

# of Collaborated Projects : 1results

# of Collaborated Products : 21results
7. 多田隼人 (90623653)

# of Collaborated Projects : 1results

# of Collaborated Products : 16results
8. TANAKA Yoshihiro

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
9. TSUDA Toyonobu

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
10. Ino Hidekazu

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
11. Takamura Toshinari

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
12. IKEWAKI Katsunori

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
13. 山岸正和

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
14. 林研至

# of Collaborated Projects : 0results

# of Collaborated Products : 2results
15. 寳達明彦

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
16. 藤野陽

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
17. 蒔田直昌

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
18. 田嶋敦

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
19. 今野哲雄

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

NOHARA Atsushi 野原 淳

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ライソゾーム酸性リパーゼによる冠動脈疾患進展の機序解明と制御Principal InvestigatorOngoing

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エクソームシーケンスを用いた新規高比重リポ蛋白代謝制御因子の発見とその機能解析Ongoing

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ANGPTL8 function and development of coronary artery diseasePrincipal Investigator

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High-density lipoprotein composition and development of coronary artery diseasePrincipal Investigator

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Novel method of measuring activities of enzymes involved in lipid metabolism

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Regulation of Cardiovascular Risk Factors by Metabolism-associated Nuclear ReceptorsPrincipal Investigator

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代謝関連核内受容体遺伝子変異機能解析と肥満および脂質代謝異常Principal Investigator

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核内受容体PPAR-α遺伝子変異体機能解析と脂質代謝異常Principal Investigator

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[Journal Article] Lipid Management in a Japanese Community:Attainment Rate of Target Set by the Japan Atherosclerosis Society Guidelines for the Prevention of Atherosclerotic Cardiovascular Diseases 2012.2017

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[Journal Article] Impact of clinical signs and genetic diagnosis of familial hypercholesterolaemia on the prevalence of coronary artery disease in patients with severe hypercholesterolaemia2017

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[Journal Article] Prevalence, clinical features, and prognosis of patients with extremely low high-density lipoprotein cholesterol.2016

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[Journal Article] Minimal contribution of severe hypertriglyceridemia in L-asparaginase-associated pancreatitis developed in a child with acute lymphocytic leukemia.2016

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[Journal Article] Efficacy and Safety of Alirocumab in Japanese Patients With Heterozygous Familial Hypercholesterolemia or at High Cardiovascular Risk With Hypercholesterolemia Not Adequately Controlled With Statins - ODYSSEY JAPAN Randomized Controlled Trial.2016

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NOHARA Atsushi 野原淳

[Journal Article] Efficacy and Safety of Alirocumab in Japanese Patients With Heterozygous Familial Hypercholesterolemia or at High Cardiovascular Risk With Hypercholesterolemia Not Adequately Controlled With Statins　- ODYSSEY JAPAN Randomized Controlled Trial.2016