Matsui Tomohiro 松井智浩

… Alternative Names

MATSUI Tomohiro 松井智浩

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Researcher Number	50314828
External Links
Affiliation (Current)	2025: 日本文理大学, 保健医療学部, 教授
Affiliation (based on the past Project Information) *help	2023: 日本文理大学, 保健医療学部, 教授 2021 – 2022: 純真学園大学, 検査科学科, 准教授 2016 – 2020: 九州女子大学, 家政学部, 准教授 2015: 山口大学, 医学(系)研究科(研究院), 講師 2012 – 2013: 山口大学, 医学(系)研究科(研究院), 講師 … More 2011 – 2012: 山口大学, 大学院・医学系研究科, 講師 2007 – 2010: Yamaguchi University, 大学院・医学系研究科, 助教 2006: 山口大学, 大学院・医学系研究科, 助手 2000 – 2005: 山口大学, 医学部, 助手 2001: 山口大学, 医学部, 教授 Less
Review Section/Research Field	Principal Investigator Anesthesiology/Resuscitation studies / Basic Section 55050:Anesthesiology-related / Anesthesiology / Anesthesiology/Resuscitation studies Except Principal Investigator Anesthesiology/Resuscitation studies / Anesthesiology/Resuscitation studies / Orthopaedic surgery
Keywords	Principal Investigator 脳低温療法 / マイクログリア / 高温培養 / TNF-α / IL-17 / 低温培養 / IL-10 / 炎症性サイトカイン / 脳高温 / 脳血管内皮細胞 … More / T細胞 / ニューロン死 / 一酸化窒素(NO) / アデノシン三リン酸(ATP) / 抗炎症性サイトカイン / ケモカイン / 脳微小血管内皮細胞 / タイトジャンクション蛋白 / 接着因子 / グランザイムB / 低酸素性虚血性脳障害 / 脳低温 / NO / インターロイキン(IL)-6 / 軽度低温培養 / 一酸化窒素 / IL-6 / 炎症 / サイトカインバランス / 抗炎症サイトカイン / 脳保護作用 / 炎症反応制御 / 制御性T細胞 / JAM-A蛋白 / ω3系脂肪酸 / VEカドヘリン / リノール酸 / 脳障害 / 新生児低酸素性虚血性脳症 / 血液脳関門(BBB) / エイコサペンタエン酸 / ドコサヘキサエン酸 / ニューロン傷害性因子 / 脳保護 / 血液脳関門 / サイトカイン / ネクローシス / Neurovascular Unit / アポトーシス / パーフォリン / IL-23 / インターロイキン17 / NF-κB / TLR2 / TLR / IFN-β / TLR3 / ex vivo培養 / Toll 様受容体 / p38 MAPK / p38MAPK / ATP / インターロイキン(IL)-10 / 脳低温遼法 / 単球 / 末梢血単球 / 抗炎症 / 末梢血単核球 / 生体防御反応 … More Except Principal Investigator 神経栄養因子 / NERVE GROWTH FACTOR / APOPTOSIS / C-FOS EXPRESSION / SPINAL GLUTAMATE / NEURONAL PLASTICITY / グルタメート神経 / 脊髄細胞 / 痛み / アポトーシス / 初期癌遺伝子発現 / 神経可塑性 / Ca ENTRY BLOCKER / NEUTROPATHIC PAIN / CA ENTRY BLOCKER / NEUROPATHIC PAIN / Caチャネル阻害薬 / 脊髄グルタメート神経 / 神経因性疼痛 / 軸索伸展 / グリア / 運動機能再建 / 骨髄細胞 / 神経グリア系連関 / シナプス再構築 / ニューロン死 / 運動機能障害 / 神経過敏 / 細胞再生 / 脊髄損傷 Less

制御性T細胞の低温・高温応答からみた脳低温による炎症反応制御と脳保護作用機序Principal Investigator
- Principal Investigator
  
  松井智浩
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Nippon Bunri University
The effects of omega-3 fatty acids on the mechanism of brain injury mediated through the combination between temporal immune cells and brain microvascular cellsPrincipal Investigator
- Principal Investigator
  
  Matsui Tomohiro
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Junshin Gakuen University
  Kyushu Women's University
The mechanism of neuroprotection by brain hypothermia in the view of thermal reaction of neurovascular unitPrincipal Investigator
- Principal Investigator
  
  M Tomohiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Kyushu Women's University
Relationship between the neuroprotection by brain hypothermia and the temporal IL-23 - IL-17 production by immune cellsPrincipal Investigator
- Principal Investigator
  
  MATSUI Tomohiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Anesthesiology
- Research Institution
  Yamaguchi University
Hypothermic and hyperthermic effects on microglial regulation through cross-talk between activation of toll-like receptor and hypoxia-ischemiaPrincipal Investigator
- Principal Investigator
  
  MATSUI Tomohiro
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Temperature-dependent response in neuronal injury by hypoxia-induced microgliaPrincipal Investigator
- Principal Investigator
  
  MATSUI Tomohiro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
脳低温による脳保護機構:マイクログリアとニューロンの相互作用及びIL-10の役割Principal Investigator
- Principal Investigator
  
  松井智浩
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
脊髄損傷に対する神経幹細胞移植の細胞再生および機能再建メカニズム解析
- Principal Investigator
  
  ISHIKAWA Toshizo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Yamaguchi University
脳低温療法のニューロン保護効果におけるマイクログリアとサイトカインとの関連Principal Investigator
- Principal Investigator
  
  松井智浩
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Regenerations of Spinal Neurons and its Sensory Function in Pathological Pain following Peripheral Nerve Injury
- Principal Investigator
  
  ISHIKAWA Toshizo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  YAMAGUCHI UNIVERSITY
脳低温療法における炎症性と抗炎症性のサイトカインバランスと免疫機構との関連Principal Investigator
- Principal Investigator
  
  松井智浩
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University
Regenerations of Spinal Cord Neurons and its Sensory Function in Pathological Pain following Peripheral Nerve Injury
- Principal Investigator
  
  ISHIKAWA Toshizo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  YAMAGUCHI UNIVERSITY
サイトカインバランスよりみた脳低温療法によるニューロン保護作用機構の解明Principal Investigator
- Principal Investigator
  
  松井智浩
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Yamaguchi University

[Book] 最新臨床検査学講座　免疫検査学/輸血・移植検査学第2版2024
- Author(s)
  松井　智浩
- Total Pages
  439
- Publisher
  医歯薬出版
- ISBN
  9784263224007
- Data Source
  KAKENHI-PROJECT-23K08396
[Book] 最新臨床検査学講座/免疫検査学「赤血球抗体検査」2017
- Author(s)
  松井智浩、窪田哲朗、藤田清貴、細井英司、梶原通子、荒木延夫、長田誠、面川進、高山成伸、谷口菊代、西尾久英、西宮達也、能登谷武、藤井康彦、坊池義浩、松橋美佳、望月照次
- Total Pages
  421
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-16K10939
[Book] 臨床検査学実習書シリーズ/輸血・移植検査学実習書（第1版）（補訂）「不規則抗体の検索と同定」2016
- Author(s)
  松井　智浩、永尾　暢夫、後藤　正徳、内堀　惠美、小野寺　利恵、細井　英司、上野　一郎、米田　幸司、小黒　博之、古杉　光明、高　陽淑、谷上　純子、谷口　菊代、武貞　直子、木寺　英明
- Total Pages
  123
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-25462403
[Book] 臨床検査学講座/免疫検査学(第2版(補訂)「赤血球抗体検査」2011
- Author(s)
  松井智浩, ほか
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-22791435
[Book] 臨床検査学講座/免疫検査学第2 版(補訂)2011
- Author(s)
  松井智浩,ほか
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-22791435
[Book] 臨床検査学実習書シリーズ/輸血・移植検査学実習書第1版「不規則抗体の検索と同定」2010
- Author(s)
  松井智浩, ほか
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-22791435
[Book] 臨床検査学講座/免疫検査学第2版2010
- Author(s)
  松井智浩, ほか
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-20791077
[Book] 臨床検査学講座/免疫検査学第2版「赤血球抗体検査」2010
- Author(s)
  松井智浩, ほか
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-20791077
[Book] 臨床検査学実習書シリーズ/輸血・移植検査学実習書第1 版2010
- Author(s)
  松井智浩,ほか
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-22791435
[Journal Article] Concentration-dependent effects of proinflammatory cytokines on barrier function and tight junction protein expression in brain microvascular endothelial cells and the hypothermic and hyperthermic effects on tight junction protein expression2023
- Author(s)
  Matsui T, et al.
- Journal Title
  
  Clin Exp Neuroimmunol
  
  Volume: 14 Issue: 1 Pages: 52-60
- DOI
  10.1111/cen3.12730
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09388
[Journal Article] Reduced perforin release from T cells as a mechanism underlying hypothermia-mediated neuroprotection2020
- Author(s)
  T Matsui, Y Yoshida
- Journal Title
  
  Clinical and Experimental Neuroimmunology
  
  Volume: 11 Issue: 1 Pages: 57-64
- DOI
  10.1111/cen3.12550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09388
[Journal Article] Bartonella henselae DNA in Seronegative Patients with Cat-Scratch Disease2018
- Author(s)
  M.Yanagihara, H.Tsuneoka, A.Tanimoto, K.Otsuyama, J.Nishikawa, T.Matsui, J.Nojima, K.Ichihara
- Journal Title
  
  Emerg Infect Dis
  
  Volume: 24 Issue: 5 Pages: 924-925
- DOI
  10.3201/eid2405.152033
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10939, KAKENHI-PROJECT-15K15226, KAKENHI-PROJECT-17K09013, KAKENHI-PROJECT-18K07468, KAKENHI-PROJECT-18K10047
[Journal Article] Reduction of the expression and production of adhesion molecules and chemokines by brain endothelial cells in response to tumor necrosis factor-α and interleukin-17 in hypothermia2016
- Author(s)
  Matsui T, Yoshida Y
- Journal Title
  
  Clin Exp Neuroimmunol
  
  Volume: － Issue: 2 Pages: 174-182
- DOI
  10.1111/cen3.12298
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462403, KAKENHI-PROJECT-16K10939
[Journal Article] マイクログリアおよびT細胞由来ニューロン傷害性因子の温度依存的産生2016
- Author(s)
  松井　智浩
- Journal Title
  
  山口医学
  
  Volume: －
- NAID
  130006513052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462403
[Journal Article] マイクログリアおよびT細胞由来ニューロン傷害性因子の温度依存的産生2016
- Author(s)
  松井智浩
- Journal Title
  
  山口医学
  
  Volume: 65 Pages: 81-85
- NAID
  130006513052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10939
[Journal Article] Hypothermia at 35 °C reduces the time-dependent microglial production of pro-inflammatory and anti-inflammatory factors that mediate neuronal cell death2014
- Author(s)
  Tomohiro Matsui, Yusuke Yoshida, Masashi Yanagihara, Hiromi Suenaga
- Journal Title
  
  Neurocrit Care
  
  Volume: 20 Issue: 2 Pages: 301-310
- DOI
  10.1007/s12028-013-9911-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462403
[Journal Article] Spinal Cord Ischemia/Injury2014
- Author(s)
  T Ishikawa, H Suzuki, K Ishikawa, S Yasuda, T Matsui, M Yamamoto, T Kakeda, S Yamamoto, Y Owada, TL Yaksh
- Journal Title
  
  Current Pharmaceutical Design
  
  Volume: 20 Issue: 36 Pages: 5738-5743
- DOI
  10.2174/1381612820666140204113252
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24593057, KAKENHI-PROJECT-25462403, KAKENHI-PROJECT-26350122
[Journal Article] 保健学科における学部教育の検証2013
- Author(s)
  上田順子、尾野緑、篠原紀幸、松井智浩、柳原正志、末永弘美
- Journal Title
  
  臨床検査学教育
  
  Volume: 5 Pages: 13-16
- Data Source
  KAKENHI-PROJECT-25462403
[Journal Article] Hypothermia Reduces Toll-Like Receptor 3-Activated Microglial Interferon-β and Nitric Oxide Production2013
- Author(s)
  Tomohiro Matsui
- Journal Title
  
  Mediators Inflamm
  
  Volume: 2013 Pages: 1-7
- DOI
  10.1155/2013/436263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435
[Journal Article] Anti-phospholipid antibodies contribute to arteriosclerosis in patients with systemic lupus erythematosus through induction of tissue factor expression and cytokine production from peripheral blood mononuclear cells2012
- Author(s)
  Yukari Motoki
- Journal Title
  
  Thromb Res
  
  Volume: 130 Issue: 4 Pages: 667-673
- DOI
  10.1016/j.thromres.2011.11.048
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435, KAKENHI-PROJECT-23590673, KAKENHI-PROJECT-24790554
[Journal Article] Temperature-Related Effects of Adenosine Triphosphate-Activated Microglia on Pro-Inflammatory Factors2012
- Author(s)
  Tomohiro MATSUI, et al
- Journal Title
  
  Neurocrit.Care
  
  Volume: (in press) Issue: 2 Pages: 293-300
- DOI
  10.1007/s12028-011-9639-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435, KAKENHI-PROJECT-23390201, KAKENHI-PROJECT-24590696
[Journal Article] Temperature- and time-dependent changes in TLR2-activated microglial NF-κB activity and concentrations of inflammatory and anti-inflammatory factors2012
- Author(s)
  Tomohiro Matsui
- Journal Title
  
  Intensive Care Med
  
  Volume: 38 Issue: 8 Pages: 1392-1399
- DOI
  10.1007/s00134-012-2591-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435, KAKENHI-PROJECT-23590673, KAKENHI-PROJECT-24590696
[Journal Article] Temperature-related effects of adenosine triphosphate-activated microglia on pro-inflammatory factors2012
- Author(s)
  Matsui T、Motoki Y、Inomoto T、Miura D、Kato Y、Suenaga H、Hino K、Nojima J
- Journal Title
  
  Neurocrit Care
  
  Volume: 17巻 Pages: 293-300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435
[Journal Article] Temperature- and time-dependent changes in TLR2-activated microglial NF-κB activity and concentrations of inflammatory and anti-inflammatory factors2012
- Author(s)
  Matsui T、Tasaki M、Yoshioka T、Motoki Y、Tsuneoka H、Nojima J
- Journal Title
  
  Intensive Care Med
  
  Volume: 38巻 Pages: 1392-1399
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435
[Journal Article] Anti-phospholipid antibodies contribute to arteriosclerosis in patients with systemic lupus erythematosus through induction of tissue factor expression and cytokine production from peripheral blood mononuclear cells2012
- Author(s)
  Motoki Y、Nojima J 、Yanagihara M 、Tsuneoka H 、Matsui T、Yamamoto M 、Ichihara K
- Journal Title
  
  Thromb Res
  
  Volume: 130巻 Pages: 667-673
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435
[Journal Article] 野島順三、軽度低温は TLR2活性化マイクログリアの NF-κB 活性化阻害を介し炎症性・抗炎症性因子産生を抑制する2011
- Author(s)
  松井智浩、田崎萌、吉岡貴裕、本木由香里、木田裕之
- Journal Title
  
  神経外傷
  
  Volume: 34巻 Pages: 218-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435
[Journal Article] 'Oxidation stress index' as a possible clinical marker for the evaluation of non-Hodgkin lymphoma2011
- Author(s)
  Nojima J 、 Motoki Y 、 Tsuneoka H 、Kuratsune H、Matsui T、Yamamoto M、Yanagihara M、Hinoda Y、Ichihara K
- Journal Title
  
  Br J Haematol
  
  Volume: 155巻 Pages: 528-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435
[Journal Article] 'Oxidation stress index' as a possible clinical marker for the evaluation of non-Hodgkin lymphoma2011
- Author(s)
  Nojima J
- Journal Title
  
  British Journal of Haematology
  
  Volume: 155 Issue: 4 Pages: 528-530
- DOI
  10.1111/j.1365-2141.2011.08719.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790538, KAKENHI-PROJECT-22791435
[Journal Article] 軽度低温はTLR2活性化マイクログリアのNF-κB活性化阻害を介し炎症性・抗炎症性因子産生を抑制する2011
- Author(s)
  松井智浩, ほか
- Journal Title
  
  神経外傷
  
  Volume: 34 Pages: 218-220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435
[Journal Article] 低温・高温下におけるマイクログリアのサイトカインおよびNO産生動態2010
- Author(s)
  松井智浩
- Journal Title
  
  山口医学 59
  
  Pages: 17-21
- NAID
  10025981650
- Data Source
  KAKENHI-PROJECT-20791077
[Journal Article] Release of prostaglandin E_2 and nitric oxide from spinal microglia is dependent on activation of p38 mitogen-activated protein kinase2010
- Author(s)
  Tomohiro MATSUI, et al.
- Journal Title
  
  Anesth.Analg.
  
  Volume: 111 Pages: 554-560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435
[Journal Article] Release of prostaglandin E2and nitric oxide from spinal microglia is dependent on activation of p38 mitogen-activated protein kinase2010
- Author(s)
  Matsui T、 Svensson CI 、 Hirata Y 、Mizobata K、Hua XY、Yaksh TL
- Journal Title
  
  Anesth Analg
  
  Volume: 111巻 Pages: 554-560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791435
[Journal Article] 低温・高温下におけるマイクログリアのサイトカインおよびNO産生動態2010
- Author(s)
  松井智浩
- Journal Title
  
  山口医学 58
  
  Pages: 17-21
- NAID
  10025981650
- Data Source
  KAKENHI-PROJECT-20791077
[Journal Article] Hypothermia reduces the release of inHammatory factors via suppression of p38 MAPK in ATP-activated rat microglia2009
- Author(s)
  Tomohiro MATSUI
- Journal Title
  
  ニュー・フロンティア・プロジェクト報告集 10
  
  Pages: 54-58
- Data Source
  KAKENHI-PROJECT-20791077
[Journal Article] Hypothermia reduces the release of inflammatory factors via suppression of p38 MAPK in ATP-activated rat microglia2009
- Author(s)
  MATSUI T
- Journal Title
  
  ニュー・フロンティア・プロジェクト報告集 10
  
  Pages: 54-58
- Data Source
  KAKENHI-PROJECT-20791077
[Journal Article] IL-10 Production Is Reduced by Hypothermia but Augmented by Hyperthermia in Rat Microglia2008
- Author(s)
  TOMOHIRO MATSUI, et.al.
- Journal Title
  
  JOURNAL OF NEUROTRAUMA 25
  
  Pages: 709-715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791077
[Journal Article] The evidence for sweet substanceinduced analgesia in adult human2008
- Author(s)
  Kakeda T, Ito M, Matsui T, Ishikawa T
- Journal Title
  
  Pain Research 23
  
  Pages: 159-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791077
[Journal Article] IL-10 production is reduced by hypothermia but augmented by hyperthermia in rat microglia2008
- Author(s)
  Matsui T, Kakeda T
- Journal Title
  
  J Neurotrauma 25
  
  Pages: 709-715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20791077
[Journal Article] IL-10 Production Is Reduced by Hjrpothennia but Augmented by Hyperthermia in Rat Microglia2008
- Author(s)
  TOMOHIRO MATSUI, et. al.
- Journal Title
  
  JOURNAL OF NEUEOTRAUMA 25(6)(in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18791082
[Journal Article] Association with Increased CSF-Glutamate Release and Intracellular Signaling in the Development of Murine Neuropathic Pain2006
- Author(s)
  F.Yamada, et al.
- Journal Title
  
  Anesth-Pharmacology 18
  
  Pages: 1-14
- Data Source
  KAKENHI-PROJECT-16659410
[Journal Article] Mild hypothermia promotes pro-inflammatory cytokine production in monocytes2006
- Author(s)
  T Matsui et al.
- Journal Title
  
  J.Neurosurg.Anesthesiol. 18・1
  
  Pages: 32-36
- Data Source
  KAKENHI-PROJECT-16790877
[Journal Article] Mild hypothermia promotes pro-inflammatory cytokine production in cultured monocytes2006
- Author(s)
  T.Matsui et al.
- Journal Title
  
  J. Neurosurg. Anesthesiol. 18(3)
  
  Pages: 189-193
- Data Source
  KAKENHI-PROJECT-18791082
[Journal Article] Association with increased CSF-glutamate release and intracellular signaling in the development of murine neuropathic pain2006
- Author(s)
  F.Yamada et al.
- Journal Title
  
  Pharmacoanesthesiology 18(1)
  
  Pages: 58-63
- Data Source
  KAKENHI-PROJECT-18791082
[Journal Article] NEUROTROPHINE INDUCER, 4-METHYL CATHECHOL IMPROVES RAT NEUROPATHIC PAIN ASSOCIATED WITH ENHANCEMENT OF GFAP-IMMUNOREACTIVITY IN SPINAL CORD.2005
- Author(s)
  T.Ishikawa, M.Nishi, et al.
- Journal Title
  
  Society for Neuroscience
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] P38 MAPK and iNOS are involved in LPS-induced PGE2 release from spinal microglia2005
- Author(s)
  T.Matsui, T.Ishikawa, et al.
- Journal Title
  
  Society for Neuroscience
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] IL-10 production is inhibited by hypothermia but augmented by hyperthermia in rat microglia2005
- Author(s)
  T.Matsui
- Journal Title
  
  3rd -European Congress on Emergency Medicine
  
  Pages: 100-100
- Data Source
  KAKENHI-PROJECT-16790877
[Journal Article] Inflammation-induced GDNF improves locomotor function after spinal cord injury2005
- Author(s)
  Hashimoto M, Furukawa S, et al.
- Journal Title
  
  Neuro Report 16
  
  Pages: 99-102
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] P38 MAPK and iNOS are involved in LPS-induced PGE2 release from spinal microglia.2005
- Author(s)
  T.Matsui, T.Ishikawa, et al.
- Journal Title
  
  Society for Neuroscience
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Involvement of glial cell line-derived neurotrophic factor in activation processes of rodent macrophages.2005
- Author(s)
  Hashimoto M, Furukawa S, et al.
- Journal Title
  
  J Neurosci Res 79
  
  Pages: 476-487
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Involvement of glial cell line-derived neurotrophic factor in activation processes of rodent macrophages2005
- Author(s)
  Hashimoto M, et al.
- Journal Title
  
  J Neurosci Res 79
  
  Pages: 476-487
- Data Source
  KAKENHI-PROJECT-16659410
[Journal Article] Inflammation-induced GDNF improves locomotor function after spinal cord injury2005
- Author(s)
  Hashimoto M, et al.
- Journal Title
  
  Neuro Report 15
  
  Pages: 99-102
- Data Source
  KAKENHI-PROJECT-16659410
[Journal Article] NEUROTROPHINE INDUCER, 4-METHYL CATHECHOL IMPROVES RAT NEUROPATHIC PAIN ASSOCIATED WITH ENHANCEMENT OF GFAP-IMMUNOREACTIVITY IN SPINAL CORD2005
- Author(s)
  T.Ishikawa, M.Nishi, et al.
- Journal Title
  
  Society for Neuroscience
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Involvement of glial cell line-derived neurotrophic factor in activation processes of rodent macrophages2005
- Author(s)
  Hashimoto M, Furukawa S, et al.
- Journal Title
  
  79
  
  Pages: 476-487
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Inflammation-induced GDNF improves locomotor function after spinal cord injury.2005
- Author(s)
  Hashimoto M, Furukawa S, et al.
- Journal Title
  
  Neuro Report 16
  
  Pages: 99-102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Involvement of glial cell line-derived neurotrophic factor in activation processes of rodent macrophages2005
- Author(s)
  Hashimoto M, Furukawa S, et al.
- Journal Title
  
  J Neurosci Res 79
  
  Pages: 476-487
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] 痛覚過敏症における多様性分子機構2005
- Author(s)
  石川敏三, 松井智浩
- Journal Title
  
  第10回セロトニン研究会論文集
  
  Pages: 1-3
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Mild Hypothermia Promotes Pro-Inflammatory Cytokine Production in Monocytes2005
- Author(s)
  T Matsui, et al.
- Journal Title
  
  J Neurosurgical Anesthesiology 15
  
  Pages: 99-102
- Data Source
  KAKENHI-PROJECT-16659410
[Journal Article] A Novel Ca Channel blocker, Cilinidipine, Inhibits Formalin-evoked Pain Responses in Relation to Spinal Glutamate Release in Rats2005
- Author(s)
  Y.Matsumoto, T.Ishikawa, et al.
- Journal Title
  
  Neurosci Lets (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] COX-1 and COX-2 dependent release of PGE_2 from LPS-activated spinal microglia2004
- Author(s)
  T.Matsui
- Journal Title
  
  The 2nd Asian Pain Symposium
  
  Pages: 64-64
- Data Source
  KAKENHI-PROJECT-16790877
[Journal Article] Mild hypothermia inhibits IL-10 production in peripheral blood Mononuclear cells.2004
- Author(s)
  Matsui T, Ishikawa T, et al.
- Journal Title
  
  Acta Anaesthesiol.Scand. 48
  
  Pages: 205-210
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Biochemical and physical treatment in rat neuropathic pain and nerve growth factor2004
- Author(s)
  M.Nishi, T.Ishikawa, et al.
- Journal Title
  
  PAIN RESEARCH 19.4
  
  Pages: 141-149
- NAID
  10013596382
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Magnetic Field Stimulation Improves Rat Neuropathic Pain : Possible Involvement of Nerve Growth Factor.2004
- Author(s)
  T Ishikawa, M Nishi, et al.
- Journal Title
  
  The 2nd Asian Pain Symposium(proceeding) 54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Axonal regrowth downregulates the synthesis of glial cell line- derived neurotrophic factor in the lesioned rat sciatic nerve.2004
- Author(s)
  Yamada Y, Furukawa S, et al.
- Journal Title
  
  J Neuro Lett. 364
  
  Pages: 11-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Axonal regrowth downregulates the synthesis of glial cell line-derived neurotrophic factor in the lesioned rat sciatic nerve2004
- Author(s)
  Yamada Y, Furukawa S, et al.
- Journal Title
  
  J Neuro Lett 364
  
  Pages: 11-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Biochemical and physical treatment in rat neuropathic pain and nerve growth factor2004
- Author(s)
  M.Nishi, T.Ishikawa, et al.
- Journal Title
  
  PAIN RESEARCH 19.4
  
  Pages: 141-149
- NAID
  10013596382
- Data Source
  KAKENHI-PROJECT-16659410
[Journal Article] Mild hypothermia inhibits IL-10 production in peripheral blood mononuclear cells2004
- Author(s)
  T.Matsui
- Journal Title
  
  Acta Anaesthesiol.Scand. 48
  
  Pages: 205-210
- Data Source
  KAKENHI-PROJECT-16790877
[Journal Article] Mild hypothermia inhibits IL-10 production in peripheral blood Mononuclear cells2004
- Author(s)
  Matsui T, Ishikawa T, et al.
- Journal Title
  
  Acta Anaesthesiol.Scand. 48
  
  Pages: 205-210
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Magnetic Field Stimulation Improves Rat Neuropathic Pain : Possible Involvement of Nerve Growth Factor2004
- Author(s)
  T Ishikawa, M Nishi, et al.
- Journal Title
  
  The 2nd Asian Pain Symposium (proceeding)
  
  Pages: 54-54
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] COX-1 and COX-2 Dependent Release of PGE2 from LPS-activated Spinal Microglia2004
- Author(s)
  T Matsui, T Ishikawa, et al.
- Journal Title
  
  The 2nd Asian Pain Symposium (proceeding)
  
  Pages: 64-64
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] COX-1 and COX-2 Dependent Release of PGE2 from LPS-activated Spinal Microglia.2004
- Author(s)
  T Matsui, T Ishikawa, et al.
- Journal Title
  
  The 2nd Asian Pain Symposium(proceeding) 64
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] INFLAMMATORY MEDIATOR, 5HT DOES NOT INFLUENCE NGF-RELATED HYPERALGESIA IN RATS2004
- Author(s)
  T.Ishikawa, Y.Matsumoto, et al.
- Journal Title
  
  Neuroscience 289.8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Inflammatory Mediator, Noradrenaline Possibly Influence NGF-related Hyperalgesia in Rats2004
- Author(s)
  K Yamaguchi, T Ishikawa, et al.
- Journal Title
  
  The 2nd Asian Pain Symposium (proceeding)
  
  Pages: 56-56
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Biochemical and physical treatment in rat neuropathic pain and nerve growth factor.2004
- Author(s)
  M.Nishi, T.Ishikawa, et al.
- Journal Title
  
  PAIN RESEARCH. 19.4
  
  Pages: 141-149
- NAID
  10013596382
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Inflammatory Mediator, Noradrenaline Possibly Influence NGF-related Hyperalgesia in Rats.2004
- Author(s)
  K Yamaguchi, T Ishikawa, et al.
- Journal Title
  
  The 2nd Asian Pain Symposium(proceeding) 56
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] INFLAMMATORY MEDIATOR, 5HT DOES NOT INFLUENCE NGF-RELATED HYPERALGESIA IN RATS2004
- Author(s)
  T.Ishikawa, Y.Matsumoto, et al.
- Journal Title
  
  Neuroscience
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Increased glutamate release evokes neuroplasticty of spinal cord neurons which may develop neuropathic pain in rats2003
- Author(s)
  Ishikawa T., Nishi M., et al.
- Journal Title
  
  The 1^<st> Science and Research Symposium (proceeding) 38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Effects of stellate ganglion block on traumatic trigeminal neuropathy2003
- Author(s)
  Sakamoto E, Ishikawa T., et al.
- Journal Title
  
  Pain Research Vol.18 No.1
  
  Pages: 25-30
- NAID
  10010514507
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Increased glutamate release evokes neuroplasticty of spinal cord neurons which may develop neuropathic pain in rats2003
- Author(s)
  Ishikawa T., Nishi M, et al.
- Journal Title
  
  The 1^<st> Science and Research Symposium (proceeding)
  
  Pages: 38-38
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] Effects of stellate ganglion block on traumatic trigeminal neuropathy.2003
- Author(s)
  Sakamoto E., Ishikawa T., et al.
- Journal Title
  
  Pain Research Vol.18 No.1
  
  Pages: 25-30
- NAID
  10010514507
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Journal Article] A Novel Ca Channel blocker, Cilnidipine, Inhibits Formalin-evoked Pain Responses in Relation to Spinal Glutamate Release in Rats.
- Author(s)
  Y.Matsumoto, T.Ishikawa, et al.
- Journal Title
  
  Neurosci Lets (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390475
[Presentation] Hypothermia reduces and hyperthermia augments T cell-derived release of perforin that mediates the death of brain endothelial cells and neuronal cells2018
- Author(s)
  T.Matsui
- Organizer
  ７th International Hypothermia & Temperature Management Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10939
[Presentation] TLR2活性化マイクログリアのNF-κB活性化と炎症性・抗炎症性因子産生の時系列的温度依存性変化2015
- Author(s)
  松井　智浩
- Organizer
  第121回山口大学医学会学術講演会
- Place of Presentation
  霜仁会館（山口県・宇部市）
- Year and Date
  2015-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-25462403
[Presentation] 35℃の低温はマイクログリアの神経傷害的炎症性および抗炎症性因子産生を時系列的に抑制する2013
- Author(s)
  松井　智浩、吉田　雄介
- Organizer
  第1６回日本脳低温療法学会
- Place of Presentation
  キャッスルプラザ(名古屋市)
- Data Source
  KAKENHI-PROJECT-25462403
[Presentation] 低酸素性虚血性脳障害由来マイクログリアの炎症性および抗炎症性サイトカイン産生に及ぼす軽度低温の影響2012
- Author(s)
  松井智浩
- Organizer
  第15回日本脳低温療法学会
- Place of Presentation
  横浜シンポジア（横浜市）
- Data Source
  KAKENHI-PROJECT-22791435
[Presentation] 低酸素性虚血性脳障害由来マイクログリアの炎症性および抗炎症性サイトカイン産生に及ぼす軽度低温の影響2012
- Author(s)
  松井智浩
- Organizer
  第15回日本脳低温療法学会
- Place of Presentation
  横浜シンポジア(神奈川県)
- Year and Date
  2012-07-06
- Data Source
  KAKENHI-PROJECT-22791435
[Presentation] 21st Century Measures for National Health Promotion2011
- Author(s)
  Matsui T
- Organizer
  7th Asia-Pacific Alliance of Health Leaders Forum
- Place of Presentation
  Chiang Mai (Thailand)
- Year and Date
  2011-10-24
- Data Source
  KAKENHI-PROJECT-22791435
[Presentation] 軽度低温は TLR2 活性化マイクログリアの NF-κB 活性化阻害を介し炎症性・抗炎症性因子産生を抑制する2011
- Author(s)
  松井智浩
- Organizer
  第34回日本脳神経外傷学会
- Place of Presentation
  誌上発表
- Year and Date
  2011-04-16
- Data Source
  KAKENHI-PROJECT-22791435
[Presentation] 21st Century Measures for National Health Promotion2011
- Author(s)
  Tomohiro MATSUI, et al
- Organizer
  7th Asia-Pacific Alliance of Health Leaders Forum
- Place of Presentation
  Chlang Mai (Thailand)
- Year and Date
  2011-10-24
- Data Source
  KAKENHI-PROJECT-22791435
[Presentation] TLR2活性化マイクログリアのNF-κB活性化と炎症性・抗炎症性因子産生の時系列的温度依存性変化2011
- Author(s)
  松井智浩, ほか
- Organizer
  第14回日本脳低温療法学会
- Place of Presentation
  かごしま県民交流センター(鹿児島市)
- Year and Date
  2011-07-02
- Data Source
  KAKENHI-PROJECT-22791435
[Presentation] TLR2 活性化マイクログリアのNF-κB 活性化と炎症性・抗炎症性因子産生の時系列的温度依存性変化2011
- Author(s)
  松井智浩
- Organizer
  第14回日本脳低温療法学会
- Place of Presentation
  かごしま県民交流センター(鹿児島県)
- Year and Date
  2011-07-02
- Data Source
  KAKENHI-PROJECT-22791435
[Presentation] 軽度低温は ATP 活性化マイクログリアの p38 MAPK 活性化阻害を介し炎症性因子を抑制する2010
- Author(s)
  松井智浩
- Organizer
  第13回日本脳低温療法学会
- Place of Presentation
  千里ライフサイエンスセンター(大阪府)
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-22791435
[Presentation] 低温・高温下におけるマイクログリアのサイトカインおよびNO産生動態(山口大学医学会中村賞受賞者講演)2010
- Author(s)
  松井智浩
- Organizer
  第113回山口大学医学会
- Place of Presentation
  宇部(山口県)
- Year and Date
  2010-02-20
- Data Source
  KAKENHI-PROJECT-20791077
[Presentation] 低温・高温下におけるマイクログリアのサイトカインおよびNO産生動態2010
- Author(s)
  松井智浩
- Organizer
  第113回山口大学医学会
- Place of Presentation
  宇部(山口県)
- Year and Date
  2010-02-20
- Data Source
  KAKENHI-PROJECT-20791077
[Presentation] 軽度低温はATP活性化マイクログリアのp38 MAPK活性化阻害を介し炎症性因子を抑制する2010
- Author(s)
  松井智浩, ほか
- Organizer
  第13回日本脳低温療法学会
- Place of Presentation
  豊中市(大阪府)千里ライフサイエンスセンター
- Year and Date
  2010-07-03
- Data Source
  KAKENHI-PROJECT-22791435
[Presentation] INFLAMMATORY FACTORS PRODUCED BY ATP-ACTIVATED MICROGLIAARE REDUCED BY HYPOTHERMIA2008
- Author(s)
  TOMOHIRO MATSUI, et.al.
- Organizer
  The 26th Annual National Neurotrauma Society Symposium
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2008-07-29
- Data Source
  KAKENHI-PROJECT-20791077
[Presentation] Inflammatory factors produced by ATP-activated microglia are reduced by hypothermia2008
- Author(s)
  Matsui T
- Organizer
  The 26th Annual National Neurotrauma Society Symposium
- Place of Presentation
  Orlando (FL, USA)
- Year and Date
  2008-07-29
- Data Source
  KAKENHI-PROJECT-20791077

1. ISHIKAWA Toshizo (90034991)

# of Collaborated Projects: 3 results

# of Collaborated Products: 25 results
2. FURUKAWA Shoei (90159129)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
3. OKANO Kozue (50160693)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TSUKAHARA Masato (20136188)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. IBUKI Takae (90232587)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 櫻井雅浩 (80344654)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KIDA Hiroyuki (70432739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 仲西修 (50137345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 山本美佐 (70379957)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 鈴木秀典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 掛田崇寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 石川浩三

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsui Tomohiro 松井 智浩

MATSUI Tomohiro 松井 智浩

Research Projects

Research Products

Co-Researchers

制御性T細胞の低温・高温応答からみた脳低温による炎症反応制御と脳保護作用機序Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The effects of omega-3 fatty acids on the mechanism of brain injury mediated through the combination between temporal immune cells and brain microvascular cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of neuroprotection by brain hypothermia in the view of thermal reaction of neurovascular unitPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

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Relationship between the neuroprotection by brain hypothermia and the temporal IL-23 - IL-17 production by immune cellsPrincipal Investigator

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Hypothermic and hyperthermic effects on microglial regulation through cross-talk between activation of toll-like receptor and hypoxia-ischemiaPrincipal Investigator

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Temperature-dependent response in neuronal injury by hypoxia-induced microgliaPrincipal Investigator

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脳低温による脳保護機構:マイクログリアとニューロンの相互作用及びIL-10の役割Principal Investigator

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脊髄損傷に対する神経幹細胞移植の細胞再生および機能再建メカニズム解析

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脳低温療法のニューロン保護効果におけるマイクログリアとサイトカインとの関連Principal Investigator

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Regenerations of Spinal Neurons and its Sensory Function in Pathological Pain following Peripheral Nerve Injury

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脳低温療法における炎症性と抗炎症性のサイトカインバランスと免疫機構との関連Principal Investigator

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Regenerations of Spinal Cord Neurons and its Sensory Function in Pathological Pain following Peripheral Nerve Injury

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サイトカインバランスよりみた脳低温療法によるニューロン保護作用機構の解明Principal Investigator

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Matsui Tomohiro 松井智浩

MATSUI Tomohiro 松井智浩

[Book] 最新臨床検査学講座　免疫検査学/輸血・移植検査学第2版2024

[Book] 臨床検査学講座/免疫検査学第2 版(補訂)2011

[Book] 臨床検査学実習書シリーズ/輸血・移植検査学実習書第1版「不規則抗体の検索と同定」2010

[Book] 臨床検査学実習書シリーズ/輸血・移植検査学実習書第1 版2010