SAKAMOTO Takashi 坂本幸士

Researcher Number	50323548
Affiliation (based on the past Project Information) *help	2010 – 2017: 東京大学, 医学部附属病院, 講師 2013: 東京大学, 大学院・医学系研究科, 講師 2010: 東京大学, 医学部, 講師 2010: 東京大学, 医学部・附属病院, 特任講師 2009: 東京大学, 医学部付属病院, 特任講師 … More 2008 – 2009: The University of Tokyo, 医学部附属病院, 助教 2007 – 2008: The University of Tokyo, 医学部・附属病院, 助教 2006: 独立行政法人国立病院機構(東京医療センター臨床研究センター), 人工臓器機器開発研究部, 研究員 2003: 東大, 医学部附属病院, 助手 2002 – 2003: 東京大学, 医学部附属病院, 助手 2001: 東京大学, 医学部・附属病院, 助手 Less
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Otorhinolaryngology Except Principal Investigator Otorhinolaryngology / Otorhinolaryngology
Keywords	Principal Investigator アポトーシス / 内耳有毛細胞 / オートファジー / ネクロトーシス / 高脂血症治療薬 / 高脂血症薬 / プロブコール / 抗脂血症薬 / 耳鼻咽喉科学 / 嗅細胞 / 嗅覚 / 強大音暴露 / カスパーゼ … More Except Principal Investigator … More 蝸牛 / glutamate / patch clamp / C57BL/6マウス / 基底膜 / 陰性荷電 / 内耳 / 耳科学 / 有毛細胞 / 酸化ストレス / 難聴 / アポトーシス / ミトコンドリア / 老化 / 水チャネル / 耳鼻咽喉科 / イソソルビド / OCT / 内リンパ水腫 / アクアポリン / 抗利尿ホルモン / メニエール病 / resting membrane potential / vacuolation / inner hair cell / カルシウム / グルタシン酸 / Patch clamp / double-patch / 空胞変性 / 静止膜電位 / 空胞変成 / 内有毛細胞 / エストロゲンβ / エストロゲンα / 透過電顕 / 免疫染色 / 蝸牛外側壁 / 更年期 / 血管条毛細血管 / エストロゲン / Estrogen receptor / 蝸牛血液-内耳関門 / 卵巣摘出 / Estrogen receptor　beta / Estrogen receptor　alpha / 血液内耳関門 / ABR / estrogen / ICRマウス / ヘパラン硫酸 / 基底膜陰性荷電 / ヘパラン硫酸プロテオグリカン / 毛細血管 / 血液―内耳関門 / 毛細血管基底膜 / 血管条 / 免疫組織学 / IgG / polyethyleneimine / 加齢性難聴 / C57BL/6 マウス / 抗加齢医学 / 脳・神経 / マイクロアレイ / 動物 / .老化 / 半規管膨大部 / 27 / Caspase3 / 未成熟ラツト / 分裂 / ネオマイシン / 有毛細胞消失 / BrdU / 増殖 / 支持細胞 / 未成熟ラット Less

内耳有毛細胞死におけるアポトーシス、ネクロトーシス、オートファジーの意義の検討Principal Investigator
- Principal Investigator
  
  坂本幸士
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
Effects of estrogen on the selective molecular transport in the inner ear
- Principal Investigator
  
  SUZUKI Mitsuya
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Toho University
Role of Vasopressin-Aquaporin2 System in the Formation of Endolymphatic Hydrops
- Principal Investigator
  
  Kakigi Akinobu
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Kobe University
  The University of Tokyo
Live imaging of the cochlear mitochondria and reactive oxygen spcies
- Principal Investigator
  
  KIKKAWA Yayoi S.
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
Analysis of genetic and environmental factors associated with the development of age-related hearing loss
- Principal Investigator
  
  YAMASOBA TATSUYA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
Probucol attenuates gentamicin-induced cochlear hair cell loss by inhibition of apoptosis.Principal Investigator
- Principal Investigator
  
  SAKAMOTO Takashi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
Age-Related Changes in the Stria Vascularis in C57BL/6 mouse
- Principal Investigator
  
  SUZUKI Mitsuya
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Toho University
Study on the mechanism of the age-related hearing loss and establishment of its preventive treatment
- Principal Investigator
  
  YAMASOBA TATSUYA
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
Clarification of mechanism of division, proliferation, differentiation, and apoptosis of supporting cells in regeneration of cochlear hair cells
- Principal Investigator
  
  SUZUKI Mitsuya
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
Analysis of apoptotic pathway in olfactory receptor neurons which causes olfactory disturbance and inhibition of apoptotic cell deathPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Takashi
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
内耳有毛細胞のアポトーシスにおけるカスパーゼ動態の定量的・経時的解析Principal Investigator
- Principal Investigator
  
  坂本幸士
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
The trial of inner hair cell injury by double patch clamp
- Principal Investigator
  
  SUGASAWA Masashi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of TOKYO

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2004 Other

All Journal Article Presentation Other

[Journal Article] Age-related morphological changes in the basement membrane in the stria vascularis of C57BL/6 mice.2016
- Author(s)
  Suzuki M, Sakamoto T, Kashio A, Yamasoba T.
- Journal Title
  
  Eur Arch Otorhinolaryngol.
  
  Volume: 273 Issue: 1 Pages: 57-62
- DOI
  10.1007/s00405-014-3478-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462548, KAKENHI-PROJECT-26253081, KAKENHI-PROJECT-26462570
[Journal Article] Prognostic factors for long-term hearing preservation after canal-tympanoplasty for congenital aural atresia.2015
- Author(s)
  Sakamoto T, Kikuta S, Kikkawa YS, Kinoshita M, Saito Y, Kobayashi K, Kakigi A, Suzuki M, Yamasoba T
- Journal Title
  
  Europian Archives of Otorhinolaryngology
  
  Volume: 272 Issue: 11 Pages: 3151-6
- DOI
  10.1007/s00405-014-3164-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592475, KAKENHI-PROJECT-15K10744
[Journal Article] Evaluation of the internal structure of normal and pathological guinea pig cochleae using optical coherence tomography2013
- Author(s)
  Kakigi A, Takubo Y, Egami N, Kashio A, Ushio M, Sakamoto T, Yamashita S, Yamasoba T
- Journal Title
  
  Audiology and Neurotology
  
  Volume: 18 Pages: 335-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390393
[Journal Article] Age-related hearing loss in Mn-SOD heterozygous knockout mice2013
- Author(s)
  Kinoshita M, Sakamoto T, Kashio A, Shimizu T, Yamasoba T
- Journal Title
  
  Oxidative Medicine and Cellular Longevity
  
  Volume: ID325702 Pages: 1-12
- DOI
  10.1155/2013/325702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390393, KAKENHI-PROJECT-23791880
[Journal Article] Current concepts in age-related hearing loss : epidemiology and mechanistic pathways2013
- Author(s)
  Yamasoba T, Lin FR, Someya S, Kashio A, Sakamoto T, Kondo K
- Journal Title
  
  Hearing Research
  
  Volume: 303 Pages: 30-38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390393
[Journal Article] Morphological and functional changes in a new animal model of Meniere's disease2013
- Author(s)
  Egami N, Kakigi A, Sakamoto T, Takeda T, Hyodo M, Yamasoba T
- Journal Title
  
  Lab Invest
  
  Volume: 93(9) Pages: 1001-11
- Data Source
  KAKENHI-PROJECT-23592474
[Journal Article] Evaluation of the internal structure of normal and pathological Guinea pig cochleae using optical coherence tomography2013
- Author(s)
  Kakigi A, Takubo Y, Egami N, Kashio A, Ushio M, Sakamoto T, Yamashita S, Yamasoba T
- Journal Title
  
  Audiol Neurootol
  
  Volume: 18(5) Pages: 335-43
- Data Source
  KAKENHI-PROJECT-23592474
[Journal Article] Morphological and functional changes in a new animal model of Ménière's disease.2013
- Author(s)
  Egami N, Kakigi A, Sakamoto T, Takeda T, Hyodo M, Yamasoba T.
- Journal Title
  
  Lab Invest.
  
  Volume: 93 Pages: 1001-1011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293346
[Journal Article] Evaluation of the Internal Structure of Normal and Pathological Guinea Pig Cochleae Using Optical Coherence Tomography2013
- Author(s)
  A. Kakigi, Y. Takubo, N. Egami, A. Kashio, M. Ushio, T. Sakamoto, S. Yamashita and T. Yamasoba
- Journal Title
  
  Audiology and Neurotology
  
  Volume: Vol. 18 Issue: 5 Pages: 335-343
- DOI
  10.1159/000354620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13J09498, KAKENHI-PROJECT-23390393, KAKENHI-PROJECT-23791880, KAKENHI-PROJECT-24791748
[Journal Article] Age-related hearing loss in Mn-SOD heterozygous knockout mice2013
- Author(s)
  Kinoshita M, Sakamoto T, Kashio A, Shimizu T, Yamasoba T
- Journal Title
  
  Oxid Med Cell Longev
  
  Volume: 2013 Pages: 325702-325702
- Data Source
  KAKENHI-PROJECT-23592474
[Journal Article] Current concepts in age-related hearing loss : epidemiology and mechanistic pathways2013
- Author(s)
  Yamasoba T, Lin FR, Someya S, Kashio A, Sakamoto T, Kondo K
- Journal Title
  
  Hear Res
  
  Pages: 30-8
- Data Source
  KAKENHI-PROJECT-23592474
[Journal Article] Topical application of the antiapoptotic TAT-FNK protein prevents aminoglycoside-induced ototoxicity2012
- Author(s)
  Kashio A, Sakamoto T, Kakigi A, Suzuki M, Suzukawa K, Kondo K, Sato Y, Asoh S, Ohta S, Yamasoba T
- Journal Title
  
  Gene Ther
  
  Volume: 19(12) Issue: 12 Pages: 1141-1149
- DOI
  10.1038/gt.2011.204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300257, KAKENHI-PROJECT-23390393, KAKENHI-PROJECT-23791880, KAKENHI-PROJECT-24651055
[Journal Article] Short-term functional and morphological changes in guinea pig cochlea following intratympanic application of Burow’s solution2012
- Author(s)
  Suzuki M, Iwamura H, Kashio A, Sakamoto T, Yamasoba T.
- Journal Title
  
  Ann Otol. Rhinol. Laryngol
  
  Volume: 121 Pages: 67-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592500
[Journal Article] Topical application of the antiapoptotic TAT-FNK protein prevents aminoglycoside-induced ototoxicity.2012
- Author(s)
  Kashio A, Sakamoto T, Kakigi A, Suzuki M, Suzukawa K, Kondo K, Sato Y, Asoh S, Ohta S, Yamasoba T.
- Journal Title
  
  Gene Ther.
  
  Volume: 19 Pages: 1141-1149
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592500
[Journal Article] Hydrogen in drinking water attenuates noise-induced hearing loss in guinea pigs.2011
- Author(s)
  Lin Y, Kashio A, Sakamoto T, Suzukawa K, Kakigi A, Yamasoba T
- Journal Title
  
  Neurosci Lett. 487
  
  Pages: 12-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390440
[Journal Article] Hydrogen in drinking water attenuates noise-induced hearing loss in guinea pigs2011
- Author(s)
  Lin Y, Kashio A, Sakamoto T, Suzukawa K, Kakigi A, Yamasoba T
- Journal Title
  
  Neurosci Lett
  
  Volume: 487 Issue: 1 Pages: 12-6
- DOI
  10.1016/j.neulet.2010.09.064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390393
[Journal Article] Effect of Burow's solution in the guinea pig inner ear.2010
- Author(s)
  Suzuki M, Kashio A, Sakamoto T, Yamasoba T
- Journal Title
  
  Ann Otol.Rhinol.Laryngol. 119
  
  Pages: 495-500
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591973
[Journal Article] Hydrogen in drinking water attenuates noise-induced hearing loss in guinea pigs.2010
- Author(s)
  Lin Y, Kashio A, Sakamoto T, Suzukawa K, Kakigi A, Yamasoba T.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 487 Pages: 12-16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390440
[Journal Article] Effect of vitamin C depletion on age-related hearing loss in SMP30/GNL knockout mice.2009
- Author(s)
  Kashio A, Amano A, Kondo Y, Sakamoto T, Iwamura H, Suzuki M, Ishigami A, Yamasoba T
- Journal Title
  
  Biochem Biophys Res Commun. 390
  
  Pages: 394-398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390440
[Journal Article] Distribution and severity of spontaneous lesions in the neuroepithelium and Bowman's glands in mouse olfactory mucosa : age-related progression2009
- Author(s)
  Kondo K, Watanabe K, Sakamoto T, Suzukawa K, Nibu K, Kaga K, Yamasoba T
- Journal Title
  
  Cell Tissue Res. 335(3)
  
  Pages: 489-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591901
[Journal Article] Effect of vitamin C depletion on age-related hearing loss in SMP30/GNL knockout mice.2009
- Author(s)
  Kashio A, Amano A, Kondo Y, Sakamoto T, Iwamura H, Suzuki M, Ishigami A, Yamasoba T.
- Journal Title
  
  Biochem Biophys Res Commun. 390
  
  Pages: 394-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390440
[Journal Article] 外傷性外リンパ瘻の治療2008
- Author(s)
  坂本幸士、山岨達也
- Journal Title
  
  ENTONI 94
  
  Pages: 38-42
- Data Source
  KAKENHI-PROJECT-18591901
[Journal Article] Methimazole-induced cell death in rat olfactory receptor neurons occurs via apoptosis triggered through mitochondrial cytochrome c-mediated caspase-3 activation pathway2007
- Author(s)
  Sakamoto T, Kondo K, Kashio A, Suzukawa K, Yamasoba T
- Journal Title
  
  J Neurosci Res. 85(3)
  
  Pages: 548-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591901
[Journal Article] Methimazole-induced cell death in rat olfactory receptor neurons occurs via apoptosis triggered through mitochondrial cytochrome c-mediated caspase-3 activation pathway.2007
- Author(s)
  Sakamoto T
- Journal Title
  
  Journal of Neuroscience Research 85(3)
  
  Pages: 548-557
- Data Source
  KAKENHI-PROJECT-18591901
[Journal Article] A protein derived from the fusion of TAT peptide and FNK, a BCL-XL derivative, prevents cochlear hair cell death from aminoglycoside ototoxicity in vivo2007
- Author(s)
  Kashio A, Sakamoto T, Suzukawa K, Asoh S, Ohta S, Yamasoba T
- Journal Title
  
  J Neurosci Res 85(7)
  
  Pages: 1403-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591901
[Journal Article] Overexpression of ErbB-2 protein in human middle ear cholesteatomas.2004
- Author(s)
  Takashi Sakamoto
- Journal Title
  
  Laryngoscope 114
  
  Pages: 1988-1991
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671769
[Journal Article] Overexpression of ErbB-2 protein in human middle ear cholesteatomas2004
- Author(s)
  Takashi Sakamoto et al.
- Journal Title
  
  Laryngoscope 114
  
  Pages: 1988-1991
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671769
[Presentation] Age-Related Morphological Changes in the Stria Vascularis in C57BL/6.2014
- Author(s)
  Mitsuya Suzuki, Takashi Sakamoto, Yohihiro Ikemiyagi, Akinori Kashio, Tatsuya Yamasoba :
- Organizer
  37 ^<th> ARO Mid-Winter meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2014-02-22
- Data Source
  KAKENHI-PROJECT-23592500
[Presentation] Optical Coherence Tomographyによる蝸牛内部構造のリアルタイム観察2013
- Author(s)
  314. 柿木章伸、田久保勇也、江上直也、坂本幸士、山下真司、山岨達也
- Organizer
  第23回日本耳科学会総会・学術講演会
- Place of Presentation
  宮崎市宮崎ｼｰｶﾞｲﾔｺﾝﾍﾞﾝｼｮﾝｾﾝﾀｰ
- Data Source
  KAKENHI-PROJECT-25293346
[Presentation] Optical Coherence Tomographyによる蝸牛内部構造のリアルタイム観察2013
- Author(s)
  柿木章伸、田久保勇也、江上直也、松本有、坂本幸士、山下真司、山岨達也
- Organizer
  第23回日本耳科学会
- Place of Presentation
  宮崎（シーガイアコンベンションセンター）
- Data Source
  KAKENHI-PROJECT-23390393
[Presentation] Optical Coherence Tomography による蝸牛内部構造のリアルタイム観察2013
- Author(s)
  柿木章伸, 田久保勇也, 江上直也, 松本有, 坂本幸士, 山下真司, 山岨達也
- Organizer
  第23回日本耳科学会
- Place of Presentation
  宮崎(シーガイアコンベンションセンター)
- Data Source
  KAKENHI-PROJECT-23390393
[Presentation] Age-Related Changes in Basement Membrane Anionic Sites in the Cochlea2012
- Author(s)
  Mitsuya Suzuki, Takashi Sakamoto, Akinori Kashio, Yoshihiro Ikemiyagi, Tatsuya Yamasoba
- Organizer
  35 ^<th> ARO Mid-Winter meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2012-02-26
- Data Source
  KAKENHI-PROJECT-23592500
[Presentation] Age-Related Changes in Basement Membrane Anionic Sites in the Cochlea2012
- Author(s)
  Mitsuya Suzuki, Takashi Sakamoto, Akinori Kashio, Yoshihiro Ikemiyagi, Tatsuya Yamasoba:
- Organizer
  35 th ARO Mid-Winter meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23592500
[Presentation] 蝸牛の基底膜陰性荷電に対する加齢の影響2012
- Author(s)
  鈴木光也、坂本幸士、樫尾明憲、池宮城慶寛、山岨達也
- Organizer
  第113回日本耳鼻咽喉科学会
- Place of Presentation
  新潟
- Year and Date
  2012-05-10
- Data Source
  KAKENHI-PROJECT-23592500
[Presentation] 外耳道閉鎖症の術後聴力に影響を及ぼす因子に関する多重ロジスティック回帰分析による検討2011
- Author(s)
  坂本幸士、樫尾明憲、安井拓也、狩野章太郎、柿木章伸、山岨達也
- Organizer
  第21回日本耳科学会
- Place of Presentation
  宜野湾市沖縄県
- Data Source
  KAKENHI-PROJECT-23592474
[Presentation] Hydrogen in Drinking Water Attenuates Noise-Induced Hearing Loss in Guinea Pigs2011
- Author(s)
  Lin Y, Kashio A, Sakamoto T, Suzukawa K, Kakigi A, Yamasoba T.
- Organizer
  ARO midwinter meeting
- Place of Presentation
  Baltimore, U.S.A.
- Data Source
  KAKENHI-PROJECT-20390440
[Presentation] Effect of Burow's solution on the basement membrane anionic sites in the stria Vascularis.2010
- Author(s)
  Mitsuya Suzuki, Hitoshi Iwamura, Takashi Sakamoto, Akinori Kashio
- Organizer
  33^<th> ARO Mid-Winter meeting
- Place of Presentation
  CA, USA
- Year and Date
  2010-02-07
- Data Source
  KAKENHI-PROJECT-20591973
[Presentation] Changes in the structure and function of the inner ear caused by Burow's solution2009
- Author(s)
  Mitsuya Suzuki, Akinori Kashio, Takashi Sakamoto, Tatsuya Yamasoba
- Organizer
  32^<th> ARO Mid-Winter meeting
- Place of Presentation
  Baltimore, USA
- Year and Date
  2009-02-17
- Data Source
  KAKENHI-PROJECT-20591973
[Presentation] Effect of modulating vitamin C levels on age-related hearing loss2009
- Author(s)
  Tatsuya Yamasoba, Akinori Kashio, Takashi Sakamoto, Hitoshi Iwamura, Mitsuya Suzuki, Yoshitake Kondo, Akihito Ishigami
- Organizer
  ARO 32nd MidWinter Meeting
- Place of Presentation
  Baltimore, USA
- Data Source
  KAKENHI-PROJECT-20390440
[Presentation] マウスの老人性難聴に対するビタミンC の欠乏および補充の影響2009
- Author(s)
  山岨達也,樫尾明憲,近藤嘉高,石神昭人,坂本幸士,岩村忍,鈴木光也
- Organizer
  日本抗加齢医学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390440
[Presentation] C57BL/6マウスの蝸牛・脳における抗酸化物質含有量の経年齢的変化の検討2009
- Author(s)
  坂本幸士,樫尾明憲,安井拓也,鈴木光也,山岨達也
- Organizer
  聴覚アンチエイジング研究会
- Place of Presentation
  東京
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20390440
[Presentation] SMP30/GNLKOマウスを用いた加齢性難聴に対するビタミンCの影響2009
- Author(s)
  樫尾明憲,岩村均,坂本幸士,山岨達也,近藤嘉高,石上昭人
- Organizer
  聴覚アンチエイジング研究会
- Place of Presentation
  東京
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20390440
[Presentation] Effect of modulating vitamin C levels on age-related hearing loss2009
- Author(s)
  Tatsuya Yamasoba, Akinori Kashio, Takashi Sakamoto, Hitoshi Iwamura, Mitsuya Suzuki, Yoshitake Kondo, Akihito Ishigami
- Organizer
  ARO midwinter meeting
- Place of Presentation
  Baltimore, USA
- Year and Date
  2009-02-17
- Data Source
  KAKENHI-PROJECT-20390440
[Presentation] アポトーシス抑制蛋白質PTD-FNKによる薬剤性嗅上皮障害掬制の試み2008
- Author(s)
  坂本幸士
- Organizer
  東京大学生命科学研究ネットワークシンポジウム2008
- Place of Presentation
  東京大学安田講堂
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-18591901
[Presentation] アポトーシス抑制蛋白質PTD-FNKによる薬剤性嗅上皮障害抑制の試み2008
- Author(s)
  坂本幸士
- Organizer
  東京大学生命科学研究ネットワークシンポジウム2008
- Place of Presentation
  東京大学安田講堂
- Year and Date
  2008-09-23
- Data Source
  KAKENHI-PROJECT-18591901
[Presentation] 抗甲状腺剤メチマゾール投与によって誘発されるラット嗅細胞障害の障害様式に関する検討2007
- Author(s)
  坂本幸士
- Organizer
  日本鼻科学会
- Place of Presentation
  栃木県総合文化センター
- Year and Date
  2007-09-29
- Data Source
  KAKENHI-PROJECT-18591901
[Presentation] 抗甲状腺剤メチマゾール投与によって誘発されるラット嗅細胞障害の障害様式に関する検計2007
- Author(s)
  坂本幸士、山岨達也
- Organizer
  第46回日本鼻科学会総会・学術講演会
- Place of Presentation
  栃木県宇都宮市
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-18591901
[Presentation] Evaluation of the Endolymphatic Hydrops of Guinea Pigs Using Optical Coherence Tomography.
- Author(s)
  Kakigi A, Takubo Y, Egami N, Matsumoto Y, Sakamoto T, Yamashita S, Yamasoba T
- Organizer
  Inner Ear Biology Workshop 2014 in Kyoto
- Place of Presentation
  京都市
- Year and Date
  2014-11-01 – 2014-11-04
- Data Source
  KAKENHI-PROJECT-25293346
[Presentation] Age-Related Morphological Changes in the Stria Vascularis in C57BL/6 Mice
- Author(s)
  Mitsuya Suzuki, Takashi Sakamoto, Yoshihiro Ikemiyagi, Akinori Kashio, Tatsuya Yamasoba
- Organizer
  37th ARO MidWinter Meeting
- Place of Presentation
  San Diego, California, USA
- Data Source
  KAKENHI-PROJECT-23592500
[Presentation] 蝸牛の基底膜陰性荷電に対する加齢の影響
- Author(s)
  鈴木光也,坂本幸士,樫尾明憲,池宮城慶寛,山岨達也
- Organizer
  第113回日本耳鼻咽喉科学会
- Place of Presentation
  朱鷺メッセ(新潟県)
- Data Source
  KAKENHI-PROJECT-23592500
[]

1. YAMASOBA TATSUYA (60251302)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
2. SUZUKI Mitsuya (50302724)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
3. IWASAKI Shin-ichi (10359606)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KASHIO Akinori (20451809)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
5. KAKIGI Akinobu (60243820)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
6. KIKKAWA Yayoi (00452350)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. KONDO Kenji (40334370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. YASUI Takuya (50511466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SOMEYA Shin-ichi (50554490)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. IKEMIYAGI Yoshihiro (50439931)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. SUGASAWA Masashi (00179110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. ITO Ken (50251286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMASHITA SHINJI (40239968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. EGAMI NAOYA (10505895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. 角田晃一 (30197751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 菊田周 (00555865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 上羽瑠美 (10597131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 牛尾宗貴 (70361483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. PROLLA Tomas A.

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 太田成男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SAKAMOTO Takashi 坂本 幸士

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内耳有毛細胞死におけるアポトーシス、ネクロトーシス、オートファジーの意義の検討Principal Investigator

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Probucol attenuates gentamicin-induced cochlear hair cell loss by inhibition of apoptosis.Principal Investigator

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Analysis of apoptotic pathway in olfactory receptor neurons which causes olfactory disturbance and inhibition of apoptotic cell deathPrincipal Investigator

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内耳有毛細胞のアポトーシスにおけるカスパーゼ動態の定量的・経時的解析Principal Investigator

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[Journal Article] Age-related morphological changes in the basement membrane in the stria vascularis of C57BL/6 mice.2016

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[Journal Article] Prognostic factors for long-term hearing preservation after canal-tympanoplasty for congenital aural atresia.2015

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[Journal Article] Evaluation of the internal structure of normal and pathological guinea pig cochleae using optical coherence tomography2013

Author(s)

SAKAMOTO Takashi 坂本幸士