KUBOTA Takahiro 久保田隆廣

Researcher Number	50323580
Affiliation *help	2016 – 2018 : 新潟薬科大学, 薬学部, 教授 2013 – 2014 : 新潟薬科大学, 薬学部, 教授 2012 : 千葉科学大学, 薬学部, 准教授 2008 – 2010 : Chiba Institute of Science, 薬学部, 准教授
Review Section/Research Field	Principal Investigator Medical pharmacy
Keywords	Principal Investigator Japanese / genetic polymorphism / Crohn’s disease / CYP2D6 / Crohn's disease / オーダーメード医療 / SULT1A1 / tamoxifen / n-6 PUFA / CYP3A4/5 … More

Genetic polymorphisms in FADS1 and FADS2 alter desaturase activity in a Japanese populationPrincipal Investigator
- Principal Investigator
  
  KUBOTA Takahiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nigata University of Phermacy and Applied Life Sciences
  Chiba Institute of Science
Influence of CYP2D6, CYP3A4/5 & Sulfotransferase 1A1 polymorphism on the pharmacokinetics of Tamoxifen.Principal Investigator
- Principal Investigator
  
  KUBOTA Takahiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Chiba Institute of Science

All 2015 2013 2011 2010 2009 2008

All Journal Article Presentation Book

[Book] 確認テストと症例解析で身につける薬物速度論入門2010
- Author(s)
  久保田隆廣, 菅谷誠, 坂本新子
- Total Pages
  71
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-20590156
[Book] 確認テストと症例解析で身につける薬物速度論入門2010
- Author(s)
  久保田隆廣、菅谷誠、坂本新子
- Total Pages
  71
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-20590156
[Journal Article] A prospective study evaluating metabolic capacity of thiopurine and associated adverse reactions in Japanese patients with inflammatory bowel disease(IBD).2015
- Author(s)
  Odahara S, Uchiyama K, Kubota T, Ito Z, Takami S, Kobayashi H, Saito K, Koido S, Ohkusa T.
- Journal Title
  
  PLoS One
  
  Volume : 10 Issue : 9 Pages : 1-13
- DOI
  10.1371/journal.pone.0137798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590204
[Journal Article] アザチオプリン／６-メルカプトプリン代謝に関わる薬物代謝酵素とその遺伝的多型2015
- Author(s)
  久保田隆廣
- Journal Title
  
  医薬品相互作用研究会
  
  Volume : 38 Pages : 1-7
- Data Source
  KAKENHI-PROJECT-24590204
[Journal Article] Copy Number Variation in Sulfotransferase isoform 1A1 (SULT1A1) is significantly associated with enzymatic activity in Japanese subjects2013
- Author(s)
  Xinfeng Yu, Takahiro Kubota lshwori Dhakal, Setsuo Hasegawa, Suzanne Williams, Shogo Ozawa and Susan Kadlubar
- Journal Title
  
  Pharmacogenomics and Personalized Medicine
  
  Volume : 6 Pages : 19-24
- DOI
  10.2147/PGPM.S36579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590156
[Journal Article] 要介護者の薬を取り扱う介護職が抱える問題2011
- Author(s)
  久保田隆廣
- Journal Title
  
  千葉科学大学紀要
  
  Volume : 4 Pages : 81-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590156
[Journal Article] Thiopurine maintenance therapy for ulcerative colitis-the clinical significance of monitoring 6-thioguanine nucleotide.2010
- Author(s)
  Hanai H, Iida T, Takeuchi K, Arai O, Watanabe F, Abe J, Maruyama Y, Oohata A, Ikeya K, Kageoka M, Miwa I, Satou Y, Hosoda Y, Kubota T.
- Journal Title
  
  Inflamm Bowel Dis 16
  
  Pages : 1376-1381
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590156
[Journal Article] 新規サプリメントと医薬品の相互作用を予見する2010
- Author(s)
  久保田隆廣、吉岡慎一、川越信秀、豊田剛史、石橋範人、鈴木信孝
- Journal Title
  
  日本補完代替医療学会誌 7
  
  Pages : 67-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590156
[Journal Article] Novel CYP2C19 629c>a mutant gene detection in Japanese subjects and estimation of its effect on conformation.2010
- Author(s)
  Kimura S, Hasegawa S, Kobayashi A, Yamaguchi H, Yohda M, Kubota T.
- Journal Title
  
  Drug Discoveries & Therapeutics 4
  
  Pages : 412-417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590156
[Journal Article] Thiopurine maintenance therapy for ulcerative colitis-the clinical significance of monitoring 6-thioguanine nucleotide.2010
- Author(s)
  Hanai H, Iida T, Takeuchi K, Arai O, Watanabe F, Abe J, Maruyama Y, Oohata A, Ikeya K, Kakeoka M, Miwa K, Satou Y, Hosoda Y, Kubota T.
- Journal Title
  
  Inflammatory bowel diseases (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590156
[Journal Article] 新規サプリメントと医薬品の相互作用を予見する2010
- Author(s)
  久保田隆廣、吉岡慎一、川越信秀、豊田剛史、石橋範人、鈴木信孝
- Journal Title
  
  日本補完代替医療学会誌
  
  Volume : 7 Pages : 67-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590156
[Journal Article] Novel CYP2C19 629c>a mutant gene detection in Japanese subjects and estimation of its effect on conformation.2010
- Author(s)
  Kimura S, Hasegawa S, Kobayashi A, Yamaguchi H, Yohda M, Kubota T.
- Journal Title
  
  Drug Discoveries & Therapeutics
  
  Volume : 4 Pages : 412-417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590156
[Journal Article] Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment.2009
- Author(s)
  Uchiyama K, Nakamura M, Kubota T., Yamane T, Fujise K, Tajiri H.
- Journal Title
  
  J Gastroenterology 44
  
  Pages : 197-203
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590156
[Journal Article] Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohy drolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercapto purine treatment.2009
- Author(s)
  Uchiyama K, Nakamura M, Kubota T, Yamane T, Fuiise K, Tajiri H.
- Journal Title
  
  Journal of Gastroenterology 44
  
  Pages : 197-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590156
[Presentation] Utility of Fatty Acid Profile of Erythrocyte Membrane in Identifying Diagnostic Markers of Crohn's Disease.2015
- Author(s)
  Z. Ito, K. Uchiyama, S. Takami, S. Koido, S. Odahara, T. Kubota, T. Ohkusa.
- Organizer
  American Journal of GASTROENTEROLOGY
- Place of Presentation
  アメリカ合衆国・ハワイ州
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-24590204
[Presentation] チオプリン製剤不耐の日本人炎症性腸疾患患者におけるThiopurine S-methyl transferaseおよびInosine triphosphate pyrophosphohydrolase遺伝子の検討2009
- Author(s)
  内山幹、小田原俊一、久保田隆廣、小井戸薫雄、山根建樹、大草敏史、田尻久雄
- Organizer
  日本消化器病学会
- Place of Presentation
  札幌
- Year and Date
  2009-05-08
- Data Source
  KAKENHI-PROJECT-20590156
[Presentation] Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment.2008
- Author(s)
  T. Kubota, et al.
- Organizer
  EHRLICH II, 2nd World Conference.
- Place of Presentation
  Nurnberg, Germany
- Data Source
  KAKENHI-PROJECT-20590156
[Presentation] Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohy drolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercapto purine treatment.2008
- Author(s)
  Kubota T, Uchiyama K
- Organizer
  EHRLICH II, 2nd World Conference.
- Place of Presentation
  Nurnberg@Germany
- Year and Date
  2008-10-04
- Data Source
  KAKENHI-PROJECT-20590156

1. UCHIYAMA Kan (10385297)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
2. ODAHARA Shun-ichi (50445673)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results

KUBOTA Takahiro 久保田 隆廣

Research Projects

Research Products

Co-Researchers

Genetic polymorphisms in FADS1 and FADS2 alter desaturase activity in a Japanese populationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Influence of CYP2D6, CYP3A4/5 & Sulfotransferase 1A1 polymorphism on the pharmacokinetics of Tamoxifen.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 確認テストと症例解析で身につける薬物速度論入門2010

Author(s)

Total Pages

Publisher

Data Source

[Book] 確認テストと症例解析で身につける薬物速度論入門2010

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] A prospective study evaluating metabolic capacity of thiopurine and associated adverse reactions in Japanese patients with inflammatory bowel disease(IBD).2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] アザチオプリン／６-メルカプトプリン代謝に関わる薬物代謝酵素とその遺伝的多型2015

Author(s)

Journal Title

Data Source

[Journal Article] Copy Number Variation in Sulfotransferase isoform 1A1 (SULT1A1) is significantly associated with enzymatic activity in Japanese subjects2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 要介護者の薬を取り扱う介護職が抱える問題2011

Author(s)

Journal Title

Data Source

[Journal Article] Thiopurine maintenance therapy for ulcerative colitis-the clinical significance of monitoring 6-thioguanine nucleotide.2010

Author(s)

Journal Title

Data Source

[Journal Article] 新規サプリメントと医薬品の相互作用を予見する2010

Author(s)

Journal Title

Data Source

[Journal Article] Novel CYP2C19 629c>a mutant gene detection in Japanese subjects and estimation of its effect on conformation.2010

Author(s)

Journal Title

Data Source

[Journal Article] Thiopurine maintenance therapy for ulcerative colitis-the clinical significance of monitoring 6-thioguanine nucleotide.2010

Author(s)

Journal Title

Data Source

[Journal Article] 新規サプリメントと医薬品の相互作用を予見する2010

Author(s)

Journal Title

Data Source

[Journal Article] Novel CYP2C19 629c>a mutant gene detection in Japanese subjects and estimation of its effect on conformation.2010

Author(s)

Journal Title

Data Source

[Journal Article] Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohydrolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercaptopurine treatment.2009

Author(s)

Journal Title

Data Source

[Journal Article] Thiopurine S-methyltransferase and inosine triphosphate pyrophosphohy drolase genes in Japanese patients with inflammatory bowel disease in whom adverse drug reactions were induced by azathioprine/6-mercapto purine treatment.2009

Author(s)

Journal Title

Data Source

[Presentation] Utility of Fatty Acid Profile of Erythrocyte Membrane in Identifying Diagnostic Markers of Crohn's Disease.2015

Author(s)

Organizer

Place of Presentation

KUBOTA Takahiro 久保田隆廣