GOTO Hideo 五藤秀男

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GOTOH Hideo 五藤秀男

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Researcher Number	50323639
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2016 – 2017: 岐阜大学, 応用生物科学部, 研究員 2015: 和歌山県立医科大学, 医学部, 講師 2007 – 2011: 東京大学, 医科学研究所, 助教 2001 – 2006: The Institute of Medical Science, The University of Tokyo, Assitant Professor, 医科学研究所, 助手 2002: 東京大学, 医科学研究科, 助手
Review Section/Research Field	Principal Investigator Virology / Applied veterinary science / Applied veterinary science / Biological Sciences Except Principal Investigator Virology / Applied veterinary science / Applied veterinary science
Keywords	Principal Investigator リバース・ジェネティクス / インフルエンザウイルス / インフルエンザ / プラスミノーゲン / 病原性 / シアル酸 / 重感染 / センダイウイルス / 干渉現象 / 受容体破壊 … More / ウイルスの干渉 / ウイルス / attenuation / reverse genetics / live vaccine / equine influenza virus / 弱毒化 / 生ワクチン / ウマインフルエンザウイルス / 断片化ルシフェラーゼ / コンプリメンテーション / 断片化蛋白質 / 遺伝子再集合 / ノイラミニダーゼ / PCR / ワクチン … More Except Principal Investigator ワクチン / インフルエンザウイルス / reverse genetics / influenza virus / ベクター / インフルエンザ / リバース・ジェネティクス / リバースジェネティクス / live vaccine / 膜貫通領域 / M2蛋白質 / M2膜蛋白質 / A型インフルエンザウイルス / 生ワクチン / Vaccine / Glycoprotein / Capsid protein / DNA polymerase / Viral vector / Betaherpesvirus / Porcine cytomegalovirus / カプシッド蛋白 / 膜糖蛋白 / PCR / 糖蛋白質 / カプシッド蛋白質 / DNAポリメラーゼ / ウイルスベクター / ベータヘルペスウイルス / ブタサイトメガロウイルス / インフルンザ / プロテアーゼ / H5N1 / 高病原性鳥インフルエンザ / NS2 / 変異ウイルス Less

Study on a role of receptor destruction in homologous viral interference by Sendai virus using persistently infected cells.Principal Investigator
- Principal Investigator
  
  GOTO Hideo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Gifu University
  Wakayama Medical University
Exploration of factors that have an influence on reassortment of influenza A virusPrincipal Investigator
- Principal Investigator
  
  GOTO Hideo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
高病原性インフルエンザを制御する新規抗ウイルス薬の検索
- Principal Investigator
  
  堀本泰介
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
A novel therapeutic strategy for zoonotic emerging and reemerging infections
- Principal Investigator
  
  HORIMOTO Taisuke
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
ウイルス感染に起因する細胞外マトリックスの変化と病態発生の関連Principal Investigator
- Principal Investigator
  
  五藤秀男
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Analysis on cellular factors regulating influenza virus infection using "self-motivating" recombinant virus
- Principal Investigator
  
  HORIMOTO Taisuke
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
インフルエンザウイルス遺伝子の転写鋳型DNA断片化によるワクチン生産への応用Principal Investigator
- Principal Investigator
  
  五藤秀男
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
哺乳動物におけるインフルエンザウイルスの病原性獲得機構の解明Principal Investigator
- Principal Investigator
  
  五藤秀男
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
半生インフルエンザウイルスベクターの開発
- Principal Investigator
  
  KAWAOKA Yoshihiro
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Study on development of a live attenuated vaccine for equine influenza infection using reverse geneticsPrincipal Investigator
- Principal Investigator
  
  GOTO Hideo
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
Development of influenza live vaccine by reverse genetics
- Principal Investigator
  
  KAWAOKA Yoshihiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  The University of Tokyo
Development of a recombinant viral live vaccine for pigs
- Principal Investigator
  
  HORIMOTO Taisuke
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied veterinary science
- Research Institution
  The University of Tokyo
  Osaka Prefecture University

All 2017 2016 2015 2012 2011 2010 2009 2008 2006 2005

All Journal Article Presentation

[Journal Article] Molecular Function Analysis of Rabies Virus RNA Polymerase L Protein by Using an L Gene-Deficient Virus.2017
- Author(s)
  Nakagawa K, Kobayashi Y, Ito N, Suzuki Y, Okada K, Makino M, Goto H, Takahashi T, Sugiyama M.
- Journal Title
  
  J Virol.
  
  Volume: 91 Issue: 20
- DOI
  10.1128/jvi.00826-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08086, KAKENHI-PROJECT-15K08500
[Journal Article] Evidence that receptor destruction by the Sendai virus hemagglutinin-neuraminidase protein is responsible for homologous interference.2016
- Author(s)
  Goto, H., Ohta, K., Matsumoto, Y., Yumine, N. Nishio, M.
- Journal Title
  
  J. Virol.
  
  Volume: 90 Issue: 17 Pages: 7640-7646
- DOI
  10.1128/jvi.01087-16
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08500, KAKENHI-PROJECT-16K19143
[Journal Article] Parainfluenza virus chimeric minireplicons reveal a novel regulatory element in the leader promoter.2016
- Author(s)
  Matsumoto, Y., Ohta, K., Goto, H. Nishio, M.
- Journal Title
  
  J. Gen. Virol.
  
  Volume: 97 Issue: 7 Pages: 1520-1530
- DOI
  10.1099/jgv.0.000479
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08500, KAKENHI-PROJECT-16K19143
[Journal Article] Graf1 controls the growth of human parainfluenza virus type 2 through inactivation of RhoA signaling.2016
- Author(s)
  Ohta K, Goto H, Matsumoto Y, Yumine N, Tsurudome M, Nishio M
- Journal Title
  
  Journal of Virology
  
  Volume: 90 Issue: 20 Pages: 9394-9405
- DOI
  10.1128/jvi.01471-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460552, KAKENHI-PROJECT-15K08500, KAKENHI-PROJECT-16K19143
[Journal Article] Human parainfluenza virus type 2 V protein inhibits and antagonizes tetherin.2016
- Author(s)
  Ohta K, Goto H, Yumine N, Nishio M
- Journal Title
  
  J Gen Virol
  
  Volume: 97 Issue: 3 Pages: 561-570
- DOI
  10.1099/jgv.0.000373
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08500
[Journal Article] Enhanced growth of influenza A virus by coinfection with human parainfluenza virus type 22015
- Author(s)
  Goto H, Ihira H, Morishita K, Tsuchiya M, Ohta K, Yumine N, Tsurudome M, Nishio M
- Journal Title
  
  Med Microbiol Immunol
  
  Volume: - Issue: 3 Pages: 209-218
- DOI
  10.1007/s00430-015-0441-y
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08500, KAKENHI-PROJECT-26460552
[Journal Article] Identification of two essential aspartates for polymerase activity in parainfluenza virus L protein by a minireplicon system expressing secretory luciferase2015
- Author(s)
  Matsumoto Y, Ohta K, Yumine N, Goto H, Nishio M
- Journal Title
  
  Microbiol Immunol
  
  Volume: 59 Issue: 11 Pages: 678-683
- DOI
  10.1111/1348-0421.12329
- NAID
  40020674167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08500
[Journal Article] F1Fo-ATPase, F-type proton-translocating ATPase, at the plasma membrane is critical for efficient influenza virus budding2012
- Author(s)
  Gorai T, Goto H, Noda T, Watanabe T, Kozuka-Hata H, Oyama M, Takano R, Neumann G, Watanabe S, Kawaoka Y
- Journal Title
  
  Proceedings of National Academy of Sciences of the United States of America
  
  Volume: 109(12) Issue: 12 Pages: 4615-4620
- DOI
  10.1073/pnas.1114728109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J04699, KAKENHI-PROJECT-21580372, KAKENHI-PROJECT-23510254
[Journal Article] Strand-specific real-time RT-PCR for distinguishing influenza vRNA, cRNA, and mRNA2011
- Author(s)
  Kawakami E, Watanabe T, Fujii K, Goto H, Watanabe S, Noda T, Kawaoka Y
- Journal Title
  
  J Virol Methods
  
  Volume: 173 Issue: 1 Pages: 1-6
- DOI
  10.1016/j.jviromet.2010.12.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580372
[Journal Article] Reassortment between seasonal H1N1 and pandemic(H1N1) 2009 influenza viruses is restricted by limited compatibility among polymerase subunits2011
- Author(s)
  Octaviani CP, Goto H, Kawaoka Y
- Journal Title
  
  J Virol
  
  Volume: 85 Issue: 16 Pages: 8449-52
- DOI
  10.1128/jvi.05054-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580372
[Journal Article] A role for the C terminus of Mopeia virus nucleoprotein in its incorporation into Z protein-induced virus-like particles2010
- Author(s)
  Shtanko O, Imai M, Goto H, Lukashevich IS, Neumann G, Watanabe T, Kawaoka Y
- Journal Title
  
  J Virol
  
  Volume: 84 Issue: 10 Pages: 5415-22
- DOI
  10.1128/jvi.02417-09
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580372
[Journal Article] High level of genetic compatibility between swine-origin H1N1 and highly pathogenic avian H5N1 influenza viruses2010
- Author(s)
  Octaviani CP, Ozawa M, Yamada S, Goto H, Kawaoka Y
- Journal Title
  
  J Virol
  
  Volume: 84 Issue: 20 Pages: 10918-22
- DOI
  10.1128/jvi.01140-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580372
[Journal Article] Non-muscle myosin IIA is a functional entry receptor for herpes simplex virus-12010
- Author(s)
  Arii J, Goto H, Suenaga T, et al. 11名2番目
- Journal Title
  
  Nature
  
  Volume: 167 Issue: 7317 Pages: 859-62
- DOI
  10.1038/nature09420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580372
[Journal Article] Nucleotide sequence requirements at the 5' end of the influenza A virus M RNA segment for efficient virus replication2009
- Author(s)
  Ozawa M, Maeda J, Iwatsuki-Horimoto K, Watanabe S, Goto H, Horimoto T, Kawaoka Y
- Journal Title
  
  J Virol
  
  Volume: 83 Issue: 7 Pages: 3384-8
- DOI
  10.1128/jvi.02513-08
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580372
[Journal Article] RuvB-like protein 2 is a suppressor of influenza A virus polymerases2009
- Author(s)
  Kakugawa S, Shimojima M, Neumann G, Goto H, Kawaoka Y
- Journal Title
  
  J Virol
  
  Volume: 83 Issue: 13 Pages: 6429-34
- DOI
  10.1128/jvi.00293-09
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580372
[Journal Article] Establishment of canine RNA polymerase I-driven reverse genetics for influenza A virus : its application for H5N1 vaccine production2008
- Author(s)
  Murakami S, Horimoto T, Yamada S, Kakugawa S, Goto H, Kawaoka Y
- Journal Title
  
  J Virol 82
  
  Pages: 1605-1609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380179
[Journal Article] The development and characterization of H5 influenza virus vaccines derived from a 2003 human isolate2006
- Author(s)
  Horimoto T, Takada A, Fujii K, Goto H, Hatta M, Watanabe S, Iwatsuki-H K, Ito M, Tagawa-S Y, Yamada S, Ito H, Ito T, Imai M, Itamura S, Odagiri T, Tashiro M, Lim W, Guan Y, Peiris M, Kawaoka Y
- Journal Title
  
  Vaccine 24
  
  Pages: 3669-3676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380179
[Journal Article] A drug-resistant H5N1 flu virus2005
- Author(s)
  Le QM, Kiso M, Someya K, Sakai YT, Nguyen TH, Nguyen KH, Pham ND, Ngyen HH, Yamada S, Muramoto Y, Horimoto T, Takada A, Goto H, Suzuki T, Suzuki Y, Kawaoka Y
- Journal Title
  
  Nature 437
  
  Pages: 1108-1108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380179
[Journal Article] Avian Influenza? -the Contribution of Basic Research to Control of Influenza-2005
- Author(s)
  Goto H
- Journal Title
  
  J Jpn Soc Poult Dis 41 Supplement
  
  Pages: 9-16
- Data Source
  KAKENHI-PROJECT-16790270
[Journal Article] The importance of both the coding and segment-specific noncoding regions of the influenza A virus NS segment for its efficient incorporation into virions2005
- Author(s)
  Fujii K, Fujii Y, Noda T, Muramoto Y, Watanabe T, Takada A, Goto H, Horimoto T, Kawaoka Y
- Journal Title
  
  Virol 79
  
  Pages: 3766-3774
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17380179
[Presentation] Parainfluenza virus type 2 and 5 "chimeric" minireplicons reveal a regulatory element in the leader sequence for viral cytotoxity2015
- Author(s)
  Yusuke Matsumoto, Keisuke Ohta, Natsuko Yumine, Hideo Goto, Machiko Nishio
- Organizer
  第63回　日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08500
[Presentation] Are sialic acid molecules on the cell surface relevant to homologous interference by Sendai virus ?2015
- Author(s)
  Hideo Goto, Keisuke Ohta, Yusuke Matsumoto, Natsuko Yumine, Machiko Nishio
- Organizer
  第63回　日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08500
[Presentation] Role of a tight junction protein Claudin-1 in the interaction of human parainfluenza virus type 22015
- Author(s)
  Natsuko Yumine, Yusuke Matsumoto, Keisuke Ohta, Hideo Goto, Machiko Nishio
- Organizer
  第63回　日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08500
[Presentation] Graf1/ARHGAP26 negatively regulates the growth of human parainfluenza virus type 2 through the RhoA inactivation2015
- Author(s)
  Keisuke Ohta, Hideo Goto, Yusuke Matsumoto, Natsuko Yumine, Masato Tsurudome, Machiko Nishio
- Organizer
  第63回　日本ウイルス学会学術集会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-11-22
- Data Source
  KAKENHI-PROJECT-15K08500

1. HORIMOTO Taisuke (00222282)

# of Collaborated Projects: 7 results

# of Collaborated Products: 4 results
2. TAKADA Ayato (10292062)

# of Collaborated Projects: 6 results

# of Collaborated Products: 3 results
3. KAWAOKA Yoshihiro (70135838)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. YASUDA Jiro (10282518)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. SHIMOJIMA Masayuki (10422411)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MAEDA Ken (90284273)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KAWAGUCHI Yasushi (60292984)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUGII Shunji (70162865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TUCHIYA Kotaro (70207405)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 田島朋子 (90173145)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 伊藤直人 (20334922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 太田圭介 (90625071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
13. 松本祐介 (00735912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
14. KONDO Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. OSUMI Kunio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 鈴木由紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 鶴留雅人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

GOTO Hideo 五藤 秀男

GOTOH Hideo 五藤 秀男

Research Projects

Research Products

Co-Researchers

Study on a role of receptor destruction in homologous viral interference by Sendai virus using persistently infected cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploration of factors that have an influence on reassortment of influenza A virusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

高病原性インフルエンザを制御する新規抗ウイルス薬の検索

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel therapeutic strategy for zoonotic emerging and reemerging infections

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ウイルス感染に起因する細胞外マトリックスの変化と病態発生の関連Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis on cellular factors regulating influenza virus infection using "self-motivating" recombinant virus

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

インフルエンザウイルス遺伝子の転写鋳型DNA断片化によるワクチン生産への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

哺乳動物におけるインフルエンザウイルスの病原性獲得機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

半生インフルエンザウイルスベクターの開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study on development of a live attenuated vaccine for equine influenza infection using reverse geneticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of influenza live vaccine by reverse genetics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a recombinant viral live vaccine for pigs

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Molecular Function Analysis of Rabies Virus RNA Polymerase L Protein by Using an L Gene-Deficient Virus.2017

Author(s)

Journal Title

GOTO Hideo 五藤秀男

GOTOH Hideo 五藤秀男