TOKUNAGA Eriko 徳永えり子

Researcher Number	50325453
Affiliation *help	2016 – 2017 : 独立行政法人国立病院機構(九州がんセンター臨床研究センター), その他部局等, 乳腺科部長 2015 : 九州がんセンター, 臨床研究センター, 部長 2015 : 独立行政法人国立病院機構(九州がんセンター臨床研究センター), その他部局等, その他 2015 : 独立行政法人国立病院機構（九州がんセンター臨床研究センター）, その他部局等, 乳腺科部長 2012 – 2014 : 九州大学, 医学(系)研究科(研究院), 准教授 … More
Review Section/Research Field	Principal Investigator General surgery Except Principal Investigator Pathological medical chemistry / Digestive surgery / General surgery
Keywords	Principal Investigator 乳癌 / ホルモン受容体 / 染色体不安定性 / HER2 / 治療標的 / サブタイプ / Akt / BRCA1 / LOH / 癌抑制遺伝子 … More Except Principal Investigator micrometastasis / 遺伝子診断 / DNAミスマッチ修復 / genetic analysis / ファンコニ貧血 / 微小癌細胞 / 末梢血 / MLH1 / microsatellite instability / 分子腫瘍学 / 骨髄 / BRCA1 / 胃十二指腸外科学 / ミスマッチ修復 / リアルタイムPCR / HNPCC / 遺伝子ノックアウトマウス / peripheral blood / 微少転移 / ゲノム不安定性 / bone marrow / マイクロサテライト不安定性 / FANCJ / DNA修復系関連遺伝子 / 大腸癌 / 複製エラー / mismatch repair / 5-FU感受性 / Real-time PCR / 定量的RT-PCR Less

乳癌における癌幹細胞性、免疫チェックポイント機構関連分子発現の意義と新規治療戦略Principal InvestigatorOngoing
- Principal Investigator
  
  徳永えり子
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Hospital Organization, Kyushu Cancer Center
Gemonic alteration, molecular subtypes and drug sensitivity in breast cancerPrincipal Investigator
- Principal Investigator
  
  Tokunaga Eriko
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Hospital Organization, Kyushu Cancer Center
  Kyushu University
DNA mismatch repair gene analysis predicts the response to anticancer drug sensitivity in gastrointestinal cancers for tailored therapy.
- Principal Investigator
  
  Kakeji Yoshihiro
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kobe University
Molecular mechanisms of hormone sensitivity of hormone receptor-positive breast cancer and their application for individual treatmentPrincipal Investigator
- Principal Investigator
  
  TOKUNAGA Eriko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
Genomic instability in the absence of FANCJ and its possible contribution to tumorigenesis
- Principal Investigator
  
  KITAO Hiroyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kyushu University
Clarification of the molecular mechanism of Japanese triple negative breast cancers and the development of innovative therapy for themPrincipal Investigator
- Principal Investigator
  
  TOKUNAGA Eriko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
乳癌におけるHER2-PI3K-Akt経路の系統的解析と新しい治療標的の探索Principal Investigator
- Principal Investigator
  
  徳永えり子
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
HDAC阻害剤の抗腫瘍作用機序解明と新しい乳癌化学内分泌療法開発への応用Principal Investigator
- Principal Investigator
  
  徳永えり子
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General surgery
- Research Institution
  Kyushu University
New strategy for cancer therapy using Hi-resolution microsatellite instability analysis and Real-time quantitative reverse transcriptase polymerase reaction
- Principal Investigator
  
  MAEHARA Yoshihiko
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  KYUSHU UNIVERSITY

[Book] トリフルリジン・チピラシル塩酸塩（TAS-102: TFTD）の抗腫瘍効果における分子機序2016
- Author(s)
  北尾洋之、松岡和明、飯森真人、徳永えり子、佐伯浩司、沖英次、宮本裕士、馬場秀夫、前原喜彦
- Total Pages
  7
- Publisher
  癌と化学療法
- Data Source
  KAKENHI-PROJECT-24390321
[Journal Article] The relationship between the expression of FOXA1 and GATA3 and the efficacy of neoadjuvant endocrine therapy.2017
- Author(s)
  Tanaka K, Tokunaga E, Yamashita N, Sagara Y, Ohi Y, Taguchi K, Ohno S, Okano S, Oda Y, Maehara Y.
- Journal Title
  
  Breast Cancer
  
  Volume : 24 Pages : 384-392
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
[Journal Article] The impact of the expression of vimentin and Axl in breast cancer.2016
- Author(s)
  Tanaka K, Tokunaga E, Inoue Y, Yamashita N, Saeki H, Okano S, Kitao H, P Oki E, Oda Y, Maehara Y.
- Journal Title
  
  Clin Breast Cancer
  
  Volume : 16 Pages : 520-526
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
[Journal Article] Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women.2016
- Author(s)
  Tokunaga E, Yamashita N, Tanaka K, Inoue Y, Akiyoshi S, Saeki H, Oki E, Kitao H, Maehara Y.
- Journal Title
  
  PLoS One
  
  Volume : 11
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461949
[Journal Article] Biological and clinical significance of loss of heterozygosity at the INPP4B gene locus in Japanese breast cancer.2016
- Author(s)
  Tokunaga E, Yamashita N, Kitao H, Tanaka K, Taketani K, Inoue Y, Saeki H, Oki E, Oda Y, Maehara Y.
- Journal Title
  
  Breast
  
  Volume : 25 Pages : 62-68
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26461949, KAKENHI-PROJECT-16K19899
[Journal Article] Phase II Trial of S-1 and Oxaliplatin Plus Cetuximab for Colorectal Cancer Patients with Initially Unresectable or Not Optimally Resectable Liver Metastases (KSCC1002).2015
- Author(s)
  Oki E, Emi Y, Miyamoto Y, Kabashima A, Higashi H, Ogata Y, Ikebe M, Saeki H, Tokunaga S, Shirabe K, Beppu T, Uchida S, Takatsuki M, Sakoda M, Eguchi S, Akagi Y, Kakeji Y, Baba H, Natsugoe S, Maehara Y, Kyushu Study Group of Clinical C.
- Journal Title
  
  Ann Surg Oncol
  
  Volume : 22 Pages : 1067-74
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390321
[Journal Article] Clinical Significance of SIP1 and E-cadherin in Patients with Esophageal Squamous Cell Carcinoma.2015
- Author(s)
  Yoshida R, Morita M, Shoji F, Nakashima Y, Miura N, Yoshinaga K, Koga T, Tokunaga E, Saeki H, Oki E, Oda Y, Maehara Y
- Journal Title
  
  Ann Surg Oncol
  
  Volume : 22 Pages : 2608-2614
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10125, KAKENHI-PROJECT-24390321
[Journal Article] The 1,2-diaminocyclohexane carrier ligand in oxaliplatin induces p53-dependent transcriptional repression of factors involved in thymidylate biosynthesis.2015
- Author(s)
  Kiyonari S, Iimori M, Matsuoka K, Watanabe S, Morikawa-Ichinose T, Miura D, Niimi S, Saeki H, Tokunaga E, Oki E, Morita M, Kadomatsu K, Maehara Y, Kitao H
- Journal Title
  
  Mol Cancer Ther
  
  Volume : 14 Pages : 2332-42
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10125, KAKENHI-PROJECT-25460390, KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-26713020
[Journal Article] Trifluridine Induces p53-Dependent Sustained G2 Phase Arrest with Its Massive Misincorporation into DNA and Few DNA Strand Breaks.2015
- Author(s)
  Matsuoka K, Iimori M, Niimi S, Tsukihara H, Watanabe S, Kiyonari S, Kiniwa M, Ando K, Tokunaga E, Saeki H, Oki E, Maehara Y, Kitao H.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume : 14(4) Pages : 1004-13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460390, KAKENHI-PROJECT-24390321
[Journal Article] Epigenetic Inactivation of BRCA1 Through Promoter Hypermethylation and Its Clinical Importance in Triple-Negative Breast Cancer.2015
- Author(s)
  Yamashita N, Tokunaga E, Kitao H, Hitchins M, Inoue Y, Tanaka K, Hisamatsu Y, Taketani K, Akiyoshi S, Okada S, Oda Y, Saeki H, Oki E, Maehara Y.
- Journal Title
  
  Clin Breast Cancer
  
  Volume : 15 Pages : 498-504
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461949
[Journal Article] A luteinizing hormone-releasing hormone agonist plus an aromatase inhibitor as second-line endocrine therapy in premenopausal females with hormone receptor-positive metastatic breast cancer.2014
- Author(s)
  Tanaka K, Tokunaga E, Yamashita N, Taketani K, Akiyoshi S, Morita M, Maehara Y.
- Journal Title
  
  Surg Today
  
  Volume : in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] The early discontinuation of adjuvant hormone therapy is associated with a poor prognosis in Japanese breast cancer patients.2014
- Author(s)
  Taketani K, Tokunaga E, Yamashita N, Tanaka K, Akiyoshi S, Okada S, Ando K, Kimura Y, Saeki H, Oki E, Morita M, Kusumoto T, Maehara Y.
- Journal Title
  
  Surg Today.
  
  Volume : in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Impact of GATA-3 and FOXA1 expression in patients with hormone receptor-positive/HER2-negative breast cancer.2014
- Author(s)
  Hisamatsu Y, Tokunaga E, Yamashita N, Akiyoshi S, Okada S, Nakashima Y, Taketani K, Aishima S, Oda Y, Morita M, Maehara Y.
- Journal Title
  
  Breast Cancer
  
  Volume : なし
- Data Source
  KAKENHI-PROJECT-26461949
[Journal Article] Overexpression of metadherin/MTDH is associated with an aggressive phenotype and a poor prognosis in invasive breast cancer2014
- Author(s)
  Tokunaga E, Nakashima Y, Yamashita N, Hisamatsu Y, Okada S, Akiyoshi S, Aishima S, Kitao H, Morita M, Maehara Y
- Journal Title
  
  Breast Cancer
  
  Volume : 21 Pages : 341-9
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Molecular mechanisms regulating the hormone sensitivity of breast cancer.2014
- Author(s)
  Tokunaga E1, Hisamatsu Y, Tanaka K, Yamashita N, Saeki H, Oki E, Kitao H, Maehara Y.
- Journal Title
  
  Cancer Sci.
  
  Volume : 105(11) Pages : 1377-1377
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25861160, KAKENHI-PROJECT-26461949
[Journal Article] Impact of GATA-3 and FOXA1 expression in patients with hormone receptor-positive/HER2-negative breast cancer.2014
- Author(s)
  Hisamatsu Y, Tokunaga E, Yamashita N, Akiyoshi S, Okada S, Nakashima Y, Taketani K, Aishima S, Oda Y, Morita M, Maehara Y.
- Journal Title
  
  Breast Cancer
  
  Volume : in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Overexpression of metadherin/MTDH is associated with an aggressive phenotype and a poor prognosis in invasive breast cancer.2014
- Author(s)
  Tokunaga E, Nakashima Y, Yamashita N, Hisamatsu Y, Okada S, Akiyoshi S, Aishima S, Kitao H, Morita M, Maehara Y.
- Journal Title
  
  Breast Cancer
  
  Volume : 21 Pages : 341-349
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-23591896, KAKENHI-PROJECT-25861160
[Journal Article] Impact of second-line and later cetuximab-containing therapy and KRAS genotypes in patients with metastatic colorectal cancer: a multicenter study in Japan.2014
- Author(s)
  Saeki H, Emi Y, Kumashiro R, Otsu H, Kawano H, Ando K, Ida S, Kimura Y, Tokunaga E, Oki E, Morita M, Shimokawa M, Maehara Y
- Journal Title
  
  Surg Today.
  
  Volume : 44 Pages : 1457-1464
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390321, KAKENHI-PROJECT-24591966
[Journal Article] Differential impact of the expression of the androgen receptor by age in estrogen receptor-positive breast cancer.2013
- Author(s)
  Tokunaga E, Hisamatsu Y, Taketani K, Yamashita N, Akiyoshi S, Okada S, Tanaka K, Saeki H, Oki E, Aishima S, Oda Y, Morita M, Maehara Y.
- Journal Title
  
  Cancer Medicine
  
  Volume : 2 Pages : 763-773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Postgastrectomy prescription of mitomycin C and UFT for patients with stageIV gastric carcinoma.2013
- Author(s)
  Emi Y, Kakeji Y, Oki E, Saeki H, Ando K, Kitazono M, Sakaguchi Y, Morita M, Samura H, Ogata Y, Akagi Y, Natsugoe S, Shirouzu K, Tokunaga S, Sirzen F, Maehara Y
- Journal Title
  
  Am J Surg
  
  Volume : 18(2) Pages : 254-259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390321
[Journal Article] Luminalタイプ乳癌におけるFOXA1発現2013
- Author(s)
  徳永えり子、久松雄一、前原喜彦
- Journal Title
  
  日本臨床乳癌
  
  Volume : 70 Pages : 438-442
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Differential impact of the expression of the androgen receptor by age in estrogen receptor–positive breast cancer2013
- Author(s)
  Tokunaga E, Hisamatsu Y, Taketani K, Yamashita N, Akiyoshi S, Okada S, Tanaka K, Saeki H, Oki E, Aishima S, Oda Y, Morita M, Maehara Y
- Journal Title
  
  Cancer Med
  
  Volume : 2 Pages : 763-773
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Molecular hierarchy of heparin-binding EGF-like growth factor- regulated angiogenesis in triple-negative breast cancer2013
- Author(s)
  Yotsumoto F, Tokunaga E, Oki E, Maehara Y, Yamada H, Nakajima K, Nam SO, Miyata K, Koyanagi M, Doi K, Shirasawa S, Kuroki M, Miyamoto S
- Journal Title
  
  Mol Cancer Res
  
  Volume : 11 Pages : 506-17
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Vimentin as a poor prognostic factor for triple-negative breast cancer2013
- Author(s)
  Yamashita N, Tokunaga E, Kitao H, Hisamatsu Y, Taketani K, Akiyoshi S, Okada S, Aishima S, Morita M, Maehara Y
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume : 139 Pages : 739-46
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Phase II trial of alternatingmFOLFOX6 and FOLFIRI regimens in thefirst-line treatment for unresectableor metastatic colorectal cancer(KSCC0701).2013
- Author(s)
  Oki E, Emi Y, Akagi Y, Tokunaga S,Sadanaga N, Tanaka T, Ogata Y, SaekiH, Kakeji Y, Baba H, Nishimaki T,Natsugoe S, Shirouzu K, Maehara Y
- Journal Title
  
  Kyushu Study Group of Clinical Cancer.Oncology
  
  Volume : 84 Pages : 233-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659656, KAKENHI-PROJECT-24390321
[Journal Article] Vimentin as a poor prognostic factor for triple-negative breast cancer.2013
- Author(s)
  Yamashita N, Tokunaga E, Kitao H, Hisamatsu Y, Taketani K, Akiyoshi S, Okada S, Aishima S, Morita M, Maehara Y.
- Journal Title
  
  J Cancer Res Clin Oncol
  
  Volume : 139 Pages : 739-746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591896, KAKENHI-PROJECT-25861160
[Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple negative breast cancers2012
- Author(s)
  Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y
- Journal Title
  
  Breast Cancer
  
  Volume : 19 Pages : 161-9
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Impact of FOXA1 expression on the prognosis of patients with hormone receptor-positive breast cancer2012
- Author(s)
  Hisamatsu Y, Tokunaga E, Yamashita N, Akiyoshi S, Okada S, Nakashima Y, Aishima S, Morita M, Kakeji Y, Maehara Y
- Journal Title
  
  Ann Surg Oncol
  
  Volume : 19 Pages : 1145-52
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Loss of Heterozygosity at BRCA1 locus is significantly associated with aggressiveness and poor prognosis in breast cancer2012
- Author(s)
  Okada S, Tokunaga E, Kitao H, Akiyoshi S, Yamashita N, Saeki H, Oki E, Morita M, Kakeji Y, Maehara Y
- Journal Title
  
  Ann Surg Oncol
  
  Volume : 19 Pages : 1499-507
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Impact of FOXA1 Expression on the Prognosis of Patients with Hormone Receptor-Positive Breast Cancer.2012
- Author(s)
  Hisamatsu Y, Tokunaga E, Yamashita N, Akiyoshi S, Okada S, Nakashima Y, Aishima S, Morita M, Kakeji Y, Maehara Y.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume : 19 Pages : 1145-52
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Loss of Heterozygosity at BRCA1 Locus Is Significantly Associated with Aggressiveness and Poor Prognosis in Breast Cancer.2012
- Author(s)
  Okada S, Tokunaga E, Kitao H, Akiyoshi S, Yamashita N, Saeki H, Oki E, Morita M, Kakeji Y, Maehara Y.
- Journal Title
  
  Ann Surg Oncol.
  
  Volume : 19 Pages : 1499-507
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers.2012
- Author(s)
  Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y.
- Journal Title
  
  Breast Cancer.
  
  Volume : 19 Pages : 161-9
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Low incidence of methylation of the promoter region of the FANCF gene in Japanese primary breast cancer.2011
- Author(s)
  Tokunaga E, Okada S, Kitao H, Shiotani S, Saeki H, Endo K, Morita M, Kakeji Y, Maehara Y
- Journal Title
  
  Breast Cancer. 18(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers.2011
- Author(s)
  Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y.
- Journal Title
  
  Breast Cancer
  
  Volume : (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] 乳癌のintrinsic subtypeと治療感受性2010
- Author(s)
  徳永えり子、秋吉清百合、山下奈真、岡田敏子、前原喜彦
- Journal Title
  
  最新医学 65
  
  Pages : 1275-1289
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] Low incidence of methylation of the promoter region of the FANCF gene in Japanese primary breast cancer2010
- Author(s)
  Tokunaga E, Okada S, Kitao H, Shiotani S, Saeki H, Endo K, Morita M, Kakeji Y, Maehara Y.
- Journal Title
  
  Breast Cancer Epub
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers2010
- Author(s)
  Tokunaga E, Okada S, Yamashita N, Akiyoshi S, Kitao H, Morita M, Kakeji Y, Maehara Y
- Journal Title
  
  Breast Cancer
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] HB-EGF orchestrates the complex signals involved in triple-negative and trastuzumab-resistant breast cancer.2010
- Author(s)
  Yotsumoto F, Oki E, Tokunaga E, et al
- Journal Title
  
  Int J Cancer
  
  Volume : 127 Pages : 2707-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] Predictive factors for anthracycline-based chemotherapy for human breast cancer.2010
- Author(s)
  Miyoshi Y, Tokunaga E, et al
- Journal Title
  
  Breast Cancer
  
  Volume : 17 Pages : 103-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] 乳癌のintrinsic subtypeと治療感受性2010
- Author(s)
  徳永えり子, 他
- Journal Title
  
  最新医学
  
  Volume : 65 Pages : 1275-1289
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] Deregulation of the Akt pathway in human cancer.2008
- Author(s)
  Tokunaga E, Oki E, Egashira A, Sadanaga N, Morita M, Kakeji Y, Maehara Y
- Journal Title
  
  Curr Cancer Drug Targets. 8(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] ファンコニ貧血とゲノム不安定性2008
- Author(s)
  北尾洋之、藤中良彦、久保信英、中ノ子智徳、吉永敬士、徳永えり子、佐伯浩司、遠藤和也、森田勝、掛地吉弘、前原喜彦
- Journal Title
  
  福岡医学雑誌 99(6)
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] Deregulation of the Akt pathway in human cancer2008
- Author(s)
  Tokunaga, E・Oki, E・Kimura, A, et. al.
- Journal Title
  
  Current Cancer Drug Targets 8
  
  Pages : 27-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17790893
[Journal Article] Topoisomerase IIalpha-positive and BRCA1-negative phenotype : association with favorable response to epirubicin-based regimens for human breast cancers.2008
- Author(s)
  Miyoshi Y, Tokunaga E, et al
- Journal Title
  
  Cancer Lett 26
  
  Pages : 44-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] Low nuclear grade but not cell proliferation predictive of pathological complete response to docetaxel in human breast cancers.2008
- Author(s)
  Miyoshi Y, Tokunaga E, et al
- Journal Title
  
  J Cancer Res Clin Oncol 134
  
  Pages : 561-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] Deregulation of the Akt pathway in human cancer.2008
- Author(s)
  Tokunaga E, et al
- Journal Title
  
  Current Cancer Drug Targets 8
  
  Pages : 27-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] Coexistence of the loss of heterozygosity at the PTEN locus and HER2 overexpression enhances the Akt activity thus leading to a negative progesterone receptor expression in breast carcinoma2007
- Author(s)
  Tokunaga, E・Oki, E・Kimura, Y, et. al.
- Journal Title
  
  Breast Cancer Res Treat 101
  
  Pages : 249-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17790893
[Journal Article] Akt is frequently activated in HER2/neu-positive breast cancers and associated with poor prognosis among hormone treated patients.2006
- Author(s)
  Tokunaga E, et al.
- Journal Title
  
  Int J Cancer 118
  
  Pages : 284-289
- Data Source
  KAKENHI-PROJECT-17790893
[Journal Article] Granulomatous lobular mastitis misdiagnosed as breast carcinoma2004
- Author(s)
  Tokunaga E, Kimura Y, Maehara Y.
- Journal Title
  
  Breast J. 10
  
  Pages : 261-262
- Data Source
  KAKENHI-PROJECT-15790695
[Journal Article] No hypersensitive estrogen receptor-α mutation (K 303R) in Japanese breast carcinomas.2004
- Author(s)
  Tokunaga E, Kimura Y, Maehara Y.
- Journal Title
  
  Breast Cancer Res Treat 84
  
  Pages : 289-292
- Data Source
  KAKENHI-PROJECT-15790695
[Journal Article] Correlation with bone metastasis and high expression of CK 19 mRNA measured by quantitative RT-PCR in the bone marrow of breast cancer patients.2003
- Author(s)
  Tokunaga E, Ishida M, Kimura Y, Maehara Y.
- Journal Title
  
  Breast J. 9
  
  Pages : 440-442
- Data Source
  KAKENHI-PROJECT-15790695
[Journal Article] Impact of GATA-3 and FOXA1 expression in patients with hormone receptor-positive/ HER2-negative breast cancer
- Author(s)
  Hisamatsu Y, Tokunaga E, Yamashita N, Akiyoshi S, Okada S, Nakashima Y, Taketani K, Aishima S, Oda Y, Morita M, Maehara Y
- Journal Title
  
  Breast Cancer
  
  Volume : (in press)
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Luteinizing hormone-releasing hormone agonist plus aromatase inhibitor as second- line endocrine therapy in premenopausal women with hormone receptor-positive metastatic breast cancer
- Author(s)
  Tanaka K, Tokunaga E, Yamashita N, Taketani K, Akiyoshi S, Morita M, Maehara Y
- Journal Title
  
  Surg Today
  
  Volume : (in press)
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] The early discontinuation of adjuvant hormone therapy is associated with a poor prognosis in Japanese breast cancer
- Author(s)
  Taketani K, Tokunaga E, Yamashita N, Tanaka K, Akiyoshi S, Okada S, Ando K, Kimura Y, Saeki H, Oki E, Morita M, Kusumoto T, Maehara Y
- Journal Title
  
  Surg Today
  
  Volume : (in press)
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] Clinico- pathological features of young patients (<35 years of age) with breast cancer in a Japanese Breast Cancer Society supported study
- Author(s)
  Kataoka A, Tokunaga E, Masuda N, Shien T, Kawabata K, Miyashita M
- Journal Title
  
  Breast Cancer
  
  Volume : (in press)
- Data Source
  KAKENHI-PROJECT-23591896
[Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple-negative breast cancers.
- Author(s)
  徳永えり子, 岡田敏子, 山下奈真, 秋吉清百合, 北尾洋之, 森田勝, 掛地吉弘, 前原喜彦
- Journal Title
  
  Breast Cancer in press.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] BRCA変異乳癌
- Author(s)
  徳永えり子、北尾洋之、前原喜彦
- Journal Title
  
  Current Therapy 2011 29(5)
  
  Pages : 360-366
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] Low incidence of methylation of the promoter region of the FANCF gene in Japanese primary breast cancer
- Author(s)
  Tokunaga E, Okada S, Kitao H, Shiotani S, Saeki H, Endo K, Morita M, Kakeji Y, Maehara Y
- Journal Title
  
  Breast Cancer
  
  Volume : 18(2) Pages : 120-3
- Data Source
  KAKENHI-PROJECT-21590338
[Journal Article] The association between Akt activation and resistance to hormone therapy in metastatic breast cancer.
- Author(s)
  Tokunaga E, et al.
- Journal Title
  
  Eur J Cancer (in press)
- Data Source
  KAKENHI-PROJECT-17790893
[Journal Article] Activation of PI3K/Akt signaling and hormone resistance in breast cancer
- Author(s)
  Tokunaga E, et al.
- Journal Title
  
  Breast Cancer (in press)
- Data Source
  KAKENHI-PROJECT-17790893
[Journal Article] Aberrant hypermethylation of the promoter region or the CHFR gene is rare in primary breast cancer.
- Author(s)
  Tokunaga E, et al.
- Journal Title
  
  Breast Cancer Res Treat (in press)
- Data Source
  KAKENHI-PROJECT-17790893
[Journal Article] Predictive factors for anthracycline-based chemotherapy for human breast cancer
- Author(s)
  Miyoshi Y, Tokunaga E, et al
- Journal Title
  
  Breast Cancer (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] Low incidence of methylation of the promoter region of the FANCF gene in Japanese primary breast cancer
- Author(s)
  Tokunaga E, et al
- Journal Title
  
  Breast Cancer (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] Low incidence of methylation of the promoter region of the FANCF gene in Japanese primary breast cancer.
- Author(s)
  Tokunaga E, et al
- Journal Title
  
  Breast Cancer
  
  Volume : (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] High incidence and frequency of LOH are associated with aggressive features of high-grade HER2 and triple negative breast cancers.
- Author(s)
  Tokunaga E, et al
- Journal Title
  
  Breast Cancer
  
  Volume : (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591549
[Journal Article] Maehara Y. FANCJ expression predicts the response to 5-fluorouracil-based chemotherapy in MLH1-proficient colorectal cancer
- Author(s)
  Nakanishi R, Kitao H, Fujinaka Y, Yamashita N, Iimori M, Tokunaga E, Yamashita N, Morita M, Kakeji Y
- Journal Title
  
  Annals of Surgical Oncology(2012) in press.
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] Clinical impact of the expression of polymeraseθ in breast cancer2016
- Author(s)
  Eriko Tokunaga, Yuka Inoue, Nami Yamashita, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Yoshihiko Maehara
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461949
[Presentation] Clinical impact of the expression of APOBEC3B in breast cancer2015
- Author(s)
  Eriko Tokunaga, Nami Yamashita, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Yoshihiko Maehara
- Organizer
  日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-26461949
[Presentation] 乳癌におけるPI3K/Akt pathwayの活性化の分子機序と生物学的意義2013
- Author(s)
  徳永えり子、山下奈真、武谷憲二、田中仁寛、木村和恵、森田勝、前原喜彦
- Organizer
  第21回日本乳癌学会学術集会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] Subtype specific chromosomal aberrations in breast cancer2013
- Author(s)
  Eriko Tokunaga, Nami Yamashita, Kenji Taketani, Koji Ando, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Masaru Morita, Yoshihiko Maehara
- Organizer
  第72回　日本癌学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 乳癌におけるサブタイプと染色体異常の関連2013
- Author(s)
  徳永えり子, 山下　奈真, 武谷　憲二, 田中仁寛, 安藤幸滋, 佐伯浩司, 沖　英次, 森田勝, 前原喜彦
- Organizer
  第51回日本癌治療学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] Subtype specific chromosomal aberrations in breast cancer2013
- Author(s)
  Eriko Tokunaga, Nami Yamashita, Kimihiro Tanaka, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Masaru Morita, Yoshihiko Maehara
- Organizer
  San Antonio Breast Cancer Symposium 2013
- Place of Presentation
  San Antonio
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 乳癌におけるPI3K/Akt pathwayの活性化の生物学的意義とその分子機序2013
- Author(s)
  徳永えり子、山下奈真、武谷憲二、田中仁寛、秋吉清百合、岡田敏子、安藤幸滋、木村和恵、佐伯浩司、沖英次、森田勝、楠本哲也、前原喜彦
- Organizer
  第113回日本外科学会学術集会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] StageIII 結腸癌に対するカペシタビン術後補助化学療法の安全性確認試験KSCC0803―3年追跡結果報告―2013
- Author(s)
  江見　泰徳、徳永　章二、沖　　英次、藤田　文彦、佐村　博範、赤木　由人、澤井　照光、緒方　　裕、馬場　秀夫、夏越　祥次、前原　喜彦
- Organizer
  第51回日本癌治療学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] 乳癌におけるPI3K/Akt pathwayの活性化の生物学的意義とその分子機序2013
- Author(s)
  徳永えり子、山下　奈真、武谷　憲二、田中　仁寛、秋吉清百合、岡田　敏子、安藤　幸滋、木村　和恵、佐伯　浩司、沖　　英次、森田　　勝、楠本　哲也、前原　喜彦
- Organizer
  第113回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] 乳癌におけるサブタイプと染色体異常の関連2013
- Author(s)
  徳永えり子、山下　奈真、武谷　憲二、田中　仁寛、安藤　幸滋、佐伯　浩司、沖　　英次、森田　　勝、前原　喜彦
- Organizer
  第51回日本癌治療学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] Subtype specific chromosomal aberrations in breast cancer2013
- Author(s)
  Tokunaga E, Yamashita N, Taketani K, Ando K, Saeki H, Oki E, Kitao H, Morita M, Maehara Y
- Organizer
  第72回日本癌学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 乳癌におけるサブタイプと染色体異常の関連2013
- Author(s)
  徳永えり子,山下奈真,武谷憲二,田中仁寛,安藤幸滋,佐伯浩司,沖英次,森田勝,前原喜彦
- Organizer
  第51回日本癌治療学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] トリフルオロチミジンによるピリミジン代謝経路への影響とDNA損傷応答2013
- Author(s)
  松岡　和明、飯森　真人、月原　宏志、清成　信一、渡邊すぎ子、徳永えり子、沖　　英次、北尾　洋之、前原　喜彦
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24390321
[Presentation] Subtype specific chromosomal aberrations in breast cancer2013
- Author(s)
  Tokunaga E, Yamashita N, Tanaka K, Saeki H, Oki E, Kitao H, Morita M, Maehara Y
- Organizer
  San Antonio Breast Cancer Symposium 2013
- Place of Presentation
  サンアントニオ
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 乳癌におけるPI3K/Akt pathwayの活性化の分子機序と生物学的意義2013
- Author(s)
  徳永えり子、山下奈真、武谷憲二、田中仁寛、木村和恵、森田勝、前原喜彦
- Organizer
  第21回日本乳癌学会学術集会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 乳癌におけるPI3K/Akt pathwayの活性化の生物学的意義とその分子機序2013
- Author(s)
  徳永えり子、山下奈真、武谷憲二、田中仁寛、秋吉清百合、岡田敏子、安藤幸滋、木村和恵、佐伯浩司、沖英次、森田勝、楠本哲也、前原喜彦
- Organizer
  第113回日本外科学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 乳癌におけるPI3K/Akt pathwayの異常を標的とした治療の現状と展望2012
- Author(s)
  徳永えり子、山下奈真、秋吉清百合、武谷憲二、森田　勝、前原喜彦
- Organizer
  日本乳癌学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] BRCA1, TP53両遺伝子座にLOHのある乳癌は悪性度が高く、染色体不安定性が高度で予後不良である2012
- Author(s)
  徳永えり子、山下奈真、田中仁寛、武谷憲二、安藤幸滋、木村和恵、佐伯浩司、沖英次、森田勝、楠本哲也、前原喜彦
- Organizer
  日本癌治療学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] Different impact of the loss of heterozygosity at BRCA1 and BRCA2 loci on clinicopathological features of breast cancer2011
- Author(s)
  Tokunaga E, Okada S, Akiyoshi S, Yamashita N, Ando N, Saeki H, Oki E, Ohga T, Kitao H, Kakeji Y, Maehara Y
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 乳癌におけるAR発現とホルモン感受性の検討2011
- Author(s)
  久松雄一、徳永えり子、秋吉清百合、岡田敏子、山下奈真、森田勝、掛地吉弘、前原喜彦
- Organizer
  第19回日本乳癌学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 乳癌における転写因子GATA-3およびFOXA1の発現はホルモン受容体陽性乳癌のホルモン感受性予測因子となりうる2011
- Author(s)
  久松雄一、徳永えり子、秋吉清百合、岡田敏子、山下奈真、佐伯浩司、沖英次、掛地吉弘、前原喜彦
- Organizer
  第49回日本癌治療学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] ER陽性乳癌におけるandrogen receptor発現の意義2011
- Author(s)
  徳永えり子、久松雄一、秋吉清百合、山下奈真、安藤幸滋、佐伯浩司、沖英次、大賀丈史、掛地吉弘、前原喜
- Organizer
  第49回日本癌治療学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] The expression of GATA-3 and FOXA1 in breast cancer : the biomarkers of hormonal sensitivity in luminal type tumors2011
- Author(s)
  Hisamatsu Y, Tokunaga E, Akiyoshi S, Okada S, Yamashita N, Morita M, Kakeji Y, Maehara Y
- Organizer
  2011 ASCO Annual Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] Luminalタイプ乳癌に対する治療戦略:FOXA1, GATA-3発現の意義2011
- Author(s)
  徳永えり子、久松雄一、秋吉清百合、山下奈真、岡田敏子、森田勝、掛地吉弘、前原喜彦
- Organizer
  第19回日本乳癌学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] The expression of GATA-3 and FOXA1 in breast cancer : the biomarkers of hormonal sensitivity in luminal type tumors2011
- Author(s)
  Tokunaga E, Hisamatsu Y, Akiyoshi S, Okada S, Yamashita N, Morita M, Kakeji Y, Maehara Y
- Organizer
  第9回日本臨床腫瘍学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] Expression of Forkhead-box protein A1 (FOXA1) as a significant prognostic and predictive marker for ER-positive breast cancer.2010
- Author(s)
  Tokunaga E, Hisamatsu Y, et al
- Organizer
  Annual Meeting of American Society of Clinical Oncology (ASCO)
- Place of Presentation
  シカゴ
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] Cytoplasmic MTDH overexpression promotes metastasis and chemoresistance and leads to poor prognosis in breast cancer.2010
- Author(s)
  徳永えり子
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 5-FUによるファンコニ貧血経路活性化のメカニズム2010
- Author(s)
  北尾洋之、藤中良彦、飯森真人、ムンフボルド・トール、中西良太、山下奈真、久保信英、吉永敬士、徳永えり子、森田勝、掛地吉弘、前原喜彦
- Organizer
  第14回日本がん分子標的治療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] 5-FUによるファンコニ貧血経路活性化におけるChk1の役割2010
- Author(s)
  北尾洋之、飯森真人、ムンフボルド・トール、藤中良彦、久保信英、中西良太、山下奈真、吉永敬士、徳永えり子、森田勝、掛地吉弘、前原喜彦
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] MTDH過剰発現と遠隔転移、抗癌剤耐性との関連:新たな分子標的としての可能性2010
- Author(s)
  徳永えり子
- Organizer
  第48回日本癌治療学会学術総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] A novel role of FancJ in the cellular response to 5-FU-induced DNA damages2010
- Author(s)
  Kitao H, Iimori M, Fujinaka Y, Kubo N, Nakanishi R, Munkhbold T, Yoshinaga K, Tokunaga E, Saeki H, Morita M, Kakeji Y, Takata M, Maehara Y.
- Organizer
  8^<th> AACR/JCA Conference
- Place of Presentation
  Hilton Waikoloa Village, Waikoloa, Hawaii, USA
- Year and Date
  2010-02-09
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] Different impact of loss of heterozygosity at BRCA1 and BRCA2 loci on breast cancer prognosis by the subtype approximated by estrogen receptor, progesterone receptor and HER22010
- Author(s)
  岡田敏子, 徳永えり子, et al
- Organizer
  AACR/JCR joint conference
- Place of Presentation
  Hawaii
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] Luminalタイプ乳癌におけるGATA-3/FOXA1/ERネットワークとホルモン感受性2010
- Author(s)
  徳永えり子、久松雄一, 他
- Organizer
  第18回日本乳癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 乳癌におけるPI3K/Akt経路の活性化とホルモン治療抵抗性とその克服2010
- Author(s)
  徳永えり子, 他
- Organizer
  第14回がん分子標的治療学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 乳癌におけるFOXA1の発現とホルモン療法感受性の検討2010
- Author(s)
  久松雄一、徳永えり子, 他
- Organizer
  第18回日本乳癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 日本人乳癌症例におけるBRCA1、BRCA2のLOHに関する研究2010
- Author(s)
  岡田敏子、徳永えり子, 他
- Organizer
  第110回日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 乳癌の分子サブタイプluminal AにおけるKi67の発現と予後および化学療法の必要性に関する研究2010
- Author(s)
  久松雄一、徳永えり子, 他
- Organizer
  第110回日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 乳癌におけるFOXO3a発現の意義2010
- Author(s)
  藤中良彦、徳永えり子, 他
- Organizer
  第110回日本外科学会定期学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] Significance of the FANCJ/BRIP1 expression in Triple-Negative Breast Cancer.2010
- Author(s)
  Yamashita N, Tokunaga E, et al
- Organizer
  22nd Annual Fanconi Anemia Research Fund Scientific Symposium
- Place of Presentation
  ミネアポリス
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] Cytoplasmic MTDH overexpression promotes metastasis and chemoresistance and leads to poor prognosis in breast cancer.2010
- Author(s)
  Tokunaga E., Okada S., et al
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] triple negative乳癌とEMTの関連についての検討2010
- Author(s)
  山下奈真、徳永えり子, 他
- Organizer
  第48回日本癌治療学会学術総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] MTDH過剰発現と遠隔転移、抗癌剤耐性との関連:新たな分子標的としての可能性2010
- Author(s)
  徳永えり子, 他
- Organizer
  第48回日本癌治療学会学術総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 乳癌においてMTDHの活性化により遠隔転移が促進され、予後不良となる2009
- Author(s)
  徳永えり子
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 日本人若年者乳がんの生物学的特徴と予後規定因子の解明2009
- Author(s)
  徳永えり子
- Organizer
  第47回日本癌治療学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 乳癌においてMTDHの活性化により遠隔転移が促進され、予後不良となる2009
- Author(s)
  徳永えり子, 他
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 日本人乳癌におけるBRCA1, BRCA2のLOHと Molecular subtype との関連2009
- Author(s)
  岡田敏子, 徳永えり子, 他
- Organizer
  第47回日本癌治療学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 日本人乳癌症例におけるBRCA1, BRCA2のLOHに関する研究2009
- Author(s)
  岡田敏子, 徳永えり子, 他
- Organizer
  第109回日本外科学会定期学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 日本人乳癌症例におけるBRCA1, BRCA2のLOHに関する研究2009
- Author(s)
  岡田敏子, 徳永えり子, 他
- Organizer
  第17回日本乳癌学会学術総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 日本人若年者乳がんの生物学的特徴と予後基底因子の解明2009
- Author(s)
  徳永えり子, 他
- Organizer
  第47回日本癌治療学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] トリプルネガティブ及びand HER2過剰発現乳癌における高頻度LOHと高悪性度との関連2008
- Author(s)
  徳永えり子
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] トリプルネガティブ乳癌における染色体不安定性2008
- Author(s)
  徳永えり子
- Organizer
  第16回日本乳癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] トリプルネガティブ乳癌における染色体不安定性と抗癌剤の選択2008
- Author(s)
  徳永えり子
- Organizer
  第46回日本癌治療学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 固形癌におけるPI3K/Akt経路の活性化と薬剤感受性との関連2008
- Author(s)
  徳永えり子、沖英次、定永倫明、森田勝、掛地吉弘、前原喜彦
- Organizer
  九州がんフオーラム
- Place of Presentation
  福岡市
- Year and Date
  2008-02-08
- Data Source
  KAKENHI-PROJECT-17790893
[Presentation] トリプルネガティブ乳癌における染色体不安定性2008
- Author(s)
  徳永えり子, ほか
- Organizer
  第16回日本乳癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] Basal type breast cancers are most genetically unstable among breast cancer subtypes approximated by estrogen receptor, progesterone receptor and HER22008
- Author(s)
  Tokunaga E, et al
- Organizer
  The 26th Congress of the International Association for Breast Cancer Research
- Place of Presentation
  Kurashiki, Japan
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] Basal type breast cancers are most genetically unstable among breast cancer subtypes approximated by estrogen receptor, progesterone receptor and HER2.2008
- Author(s)
  徳永えり子, et al.
- Organizer
  The 26th Congress of the International Association for Breast Cancer Research.
- Place of Presentation
  Kurashiki, Japan
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] トリプルネガティブ乳癌における染色体不安定性と抗癌剤の選択2008
- Author(s)
  徳永えり子, ほか
- Organizer
  第46回日本癌治療学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] トリプルネガティブ及びand HER2過剰発現乳癌における高頻度LOHと高悪性度との関連2008
- Author(s)
  徳永えり子, ほか
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20591549
[Presentation] 乳癌におけるHER2過剰発現、PTEN LOHによるAkt経路の活性化とプロゲステロン受容体発現減弱に関する研究2007
- Author(s)
  徳永えり子、塩谷聡子、岡田敏子、沖英次、江頭明典、定永倫明、森田勝、掛地吉弘、前原喜彦
- Organizer
  第15回日本乳癌学会学術総会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-17790893
[Presentation] 乳癌の予後変遷とサブタイプとの関連
- Author(s)
  徳永えり子, 山下奈真, 田中仁寛, 上尾裕紀, 安藤幸滋, 佐伯浩司, 沖英次, 森田勝, 前原喜彦
- Organizer
  第52回　日本癌治療学会学術集会
- Place of Presentation
  横浜市
- Year and Date
  2014-08-28 – 2014-08-30
- Data Source
  KAKENHI-PROJECT-26461949
[Presentation] 術前薬物療法のトランスレーショナルリサーチ
- Author(s)
  徳永えり子、山下奈真、田中仁寛、森田　勝、前原喜彦
- Organizer
  第22回日本乳癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2014-07-10 – 2014-07-12
- Invited
- Data Source
  KAKENHI-PROJECT-26461949
[Presentation] 5-FU感受性規定因子としてのファンコニ貧血経路
- Author(s)
  北尾洋之、藤中良彦、久保信英、中ノ子智徳、茂地智子、吉永敬士、ムンフボルド・トール、佐伯浩司、徳永えり子、江見泰徳、森田勝、掛地吉弘、前原喜彦
- Organizer
  第13回日本がん分子標的治療学会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590338
[Presentation] ER陽性乳癌における転写因子FOXA1の発現とホルモン感受性および予後に関する研究
- Author(s)
  久松　雄一、徳永えり子、秋吉清百合、山下　奈真、岡田敏子、森田　　勝、掛地　吉弘、前原　喜彦
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  誌上発表
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] The expression of GATA-3 and FOXA1 in breast cancer: the biomarkers of hormonal sensitivity in luminal type tumors.
- Author(s)
  Hisamatsu Y, Tokunaga E, Akiyoshi S, Okada S, Yamashita N, Morita M, Kakeji Y, Maehara Y.
- Organizer
  2011 ASCO Annual Meeting
- Place of Presentation
  Chicago, USA
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] The expression of GATA-3 and FOXA1 in breast cancer: the biomarkers of hormonal sensitivity in luminal type tumors.
- Author(s)
  Tokunaga E, Hisamatsu Y, Akiyoshi S, Okada S, Yamashita N, Morita M, Kakeji Y, Maehara Y.
- Organizer
  第9回日本臨床腫瘍学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 乳癌における転写因子GATA-3およびFOXA1の発現はホルモン受容体陽性乳癌のホルモン感受性予測因子となりうる
- Author(s)
  久松　雄一、徳永えり子、秋吉清百合、岡田　敏子、山下奈真、佐伯　浩司、沖　　英次、掛地　吉弘、前原　喜彦
- Organizer
  第49回日本癌治療学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] 乳癌におけるAR発現とホルモン感受性の検討
- Author(s)
  久松　雄一、徳永えり子、秋吉清百合、岡田　敏子、山下奈真、森田　　勝、掛地　吉弘、前原　喜彦
- Organizer
  第19回日本乳癌学会学術総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] Luminalタイプ乳癌に対する治療戦略：FOXA1, GATA-3発現の意義
- Author(s)
  徳永えり子、久松　雄一、秋吉清百合、山下　奈真、岡田敏子、森田　　勝、掛地　吉弘、前原　喜彦
- Organizer
  第19回日本乳癌学会学術総会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] FOXA1 and GATA-3: New biomarkers for ER-positive breast cancer.
- Author(s)
  Tokunaga E, Hisamatsu Y, Okada S, Yamashita N, Akiyoshi S, Morita M, Kakeji Y, Maehara Y.
- Organizer
  第111回日本外科学会定期学術集会
- Place of Presentation
  誌上発表
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] FOXA1 and GATA-3: New biomarkers for ER-positive breast cancer
- Author(s)
  Tokunaga E, Hisamatsu Y, Okada S, YamashitaN, Akiyoshi S, Morita M, Kakeji Y, Maehara Y
- Organizer
  第111回日本外科学会学術集会
- Place of Presentation
  (誌上発表)
- Data Source
  KAKENHI-PROJECT-23591896
[Presentation] Coexistence of LOH at BRCA1 and TP53 loci is associated with aggressive phenotype and poor prognosis in breast cancer
- Author(s)
  Eriko Tokunaga, Nami Yamashita, Kenji Taketani, Koji Ando, Yasue Kimura, Hiroshi Saeki, Eiji Oki, Hiroyuki Kitao, Masaru Morita, Yoshihiko Maehara
- Organizer
  日本癌学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591896

1. KITAO Hiroyuki (30368617)

# of Collaborated Projects : 4results

# of Collaborated Products : 34results
2. KAKEJI Yoshihiro (80284488)

# of Collaborated Projects : 3results

# of Collaborated Products : 12results
3. OKI Eiji (70380392)

# of Collaborated Projects : 2results

# of Collaborated Products : 14results
4. AKIYOSHI Sayuri (50567360)

# of Collaborated Projects : 2results

# of Collaborated Products : 38results
5. MORITA Masaru (30294937)

# of Collaborated Projects : 2results

# of Collaborated Products : 15results
6. SAEKI Hiroshi (80325448)

# of Collaborated Projects : 2results

# of Collaborated Products : 18results
7. MAEHARA Yoshihiko (80165662)

# of Collaborated Projects : 2results

# of Collaborated Products : 12results
8. 山下奈真 (60608967)

# of Collaborated Projects : 2results

# of Collaborated Products : 13results
9. SHIOTANI Satoko (90419549)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
10. SADANAGA Noriaki (20304826)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
11. OKADA Satoko (50546562)

# of Collaborated Projects : 1results

# of Collaborated Products : 9results
12. IIMORI Makoto (20546460)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results
13. 安藤幸滋 (20608864)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
14. 岡野慎士 (10380429)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
15. 北村薫 (70234276)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
16. 高橋郁雄 (70325439)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
17. 池田陽一 (50311840)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
18. 田口健一 (40325527)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
19. 古賀聡

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
20. BABA Hideo

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
21. 三浦大典

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

TOKUNAGA Eriko 徳永 えり子

Research Projects

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Co-Researchers

乳癌における癌幹細胞性、免疫チェックポイント機構関連分子発現の意義と新規治療戦略Principal InvestigatorOngoing

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Gemonic alteration, molecular subtypes and drug sensitivity in breast cancerPrincipal Investigator

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DNA mismatch repair gene analysis predicts the response to anticancer drug sensitivity in gastrointestinal cancers for tailored therapy.

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Molecular mechanisms of hormone sensitivity of hormone receptor-positive breast cancer and their application for individual treatmentPrincipal Investigator

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Genomic instability in the absence of FANCJ and its possible contribution to tumorigenesis

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Clarification of the molecular mechanism of Japanese triple negative breast cancers and the development of innovative therapy for themPrincipal Investigator

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乳癌におけるHER2-PI3K-Akt経路の系統的解析と新しい治療標的の探索Principal Investigator

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HDAC阻害剤の抗腫瘍作用機序解明と新しい乳癌化学内分泌療法開発への応用Principal Investigator

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New strategy for cancer therapy using Hi-resolution microsatellite instability analysis and Real-time quantitative reverse transcriptase polymerase reaction

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[Book] トリフルリジン・チピラシル塩酸塩（TAS-102: TFTD）の抗腫瘍効果における分子機序2016

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[Journal Article] The relationship between the expression of FOXA1 and GATA3 and the efficacy of neoadjuvant endocrine therapy.2017

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[Journal Article] The impact of the expression of vimentin and Axl in breast cancer.2016

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[Journal Article] Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women.2016

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[Journal Article] Biological and clinical significance of loss of heterozygosity at the INPP4B gene locus in Japanese breast cancer.2016

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[Journal Article] Phase II Trial of S-1 and Oxaliplatin Plus Cetuximab for Colorectal Cancer Patients with Initially Unresectable or Not Optimally Resectable Liver Metastases (KSCC1002).2015

TOKUNAGA Eriko 徳永えり子