HIRAI Makoto 平井誠

Researcher Number	50326849
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2013 – 2025: 順天堂大学, 医学部, 准教授 2012 – 2013: 群馬大学, 医学(系)研究科(研究院), 講師 2011: 群馬大学, 大学院・医学系, 講師 2010 – 2011: Jichi Medical University, 大学院・医学系研究科, 講師 2010: 群馬大学, 医学部, 講師 2007 – 2009: Jichi Medical University, School of Medicine, School of Medicine Assistant Professor 2000 – 2006: 自治医科大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Parasitology (including Sanitary zoology) / Biological Sciences / Basic Section 49040:Parasitology-related / Transformative Research Areas, Section (III) / Parasitology (including sanitary zoology) / Biological Sciences Except Principal Investigator Parasitology (including sanitary zoology) / Parasitology (including Sanitary zoology) / 寄生虫学(含医用動物学) / Hematology … More / Hematology / Basic Section 54030:Infectious disease medicine-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Medium-sized Section 58:Society medicine, nursing, and related fields / Morphology/Structure Less
Keywords	Principal Investigator マラリア原虫 / 受精 / ネズミマラリア原虫 / オルガネラ / ミューテーター / GCS1 / 薬剤耐性 / マラリア / アピコプラスト / ミューテーターマラリア … More / 加速進化 / 宿主特異性 / 適応度 / オルガネラゲノム編集 / ミトコンドリア / cytochrome b / アトバコン / ゲノム編集 / 熱帯熱マラリア原虫 / mutator malaria / PbGCS1 / 比較ゲノム / 生殖母体分化 / マラリアライフサイクル / 逆遺伝学的手法 / 生殖母体 / 性分化 … More Except Principal Investigator マラリア / 薬剤耐性 / ハマダラカ / 分子疫学 / グルコース6リン酸脱水素酵素 / malaria / G6PD / アジア / マラリア原虫 / 人類遺伝学 / プリマキン / 先天性代謝異常症 / アルテミシニン / Asia / primaquine / human genetics / molecular epidemiology / 貧血 / 遺伝子導入 / 伝播阻止 / 唾液腺 / MALARIA / ネパール / 中国 / 媒介蚊 / 進化 / 東南アジア / 溶血性貧血 / K13 / 薬剤耐性進化 / 実験進化 / 実験室進化 / ミューテータ / 高度変異原虫 / インタラクトーム / 受精因子 / 膜融合 / 配偶子融合 / ネズミマラリア原虫 / GCS1 / 配偶子 / 細胞間相互作用 / 膜タンパク質 / 有性生殖 / 受精 / 種内競争 / 適応度 / マラリア伝播阻止 / Ｄ－アロース / ヘキソース・トランスポーター / D-アロース / 希少糖 / Africa / hemolytic anemia / アフリカ / green fluorescent protein / anopheline mosquito / luciverin / luciferase / life cycle / transgenic parasite / スポロゾイト / ルシフェラーゼ / GFP / ルシフェリン / ルシフェレーゼ / 生活史 / anemia / metabolic abnormality / ミャンマー / インドネシア / 韓国 / カンボジア / ベトナム / Transmission-blocking / single-chain antibody / Transgcnic / Genetic manipulation / Anopheles stephensi / Malaria / トランスミッション / 一本鎖抗体 / トランスジェニック / 遺伝子操作 / MOSQUITO / CULEX / AEDES / ANOPHELES / SALIVARY GLAND / EXFLAGELLATION / GAMETOCYTE / キサントウレイン酸 / アカイエカ / ヒトスジシマカ / ネッタイシマカ / 鞭毛放出 / 生殖母体 / ASIA / NEPAL / CHINA / MOLECULAR EPIDEMIOLOGY / GENOMIC DNA / NUCLEOTIDE CHANGE / GLUCOSE 6-PHOSPHATE DEHYDROGENASE / PCR / ゲノムDNA / 塩基置換 / 細胞培養 / オオシスト培養 / 蚊体内ステージ / 突然変異 / ゲノム / Plasmodium / ミューテーター / シエラレオネ / 新生児黄疸 / グルコニス6リン酸脱水素酵素 / 感染蚊対策 / 溶血発作マラリア Less

Organelle Genome Editing Unveils Drug Resistance Mechanisms in Malaria ParasitesPrincipal Investigator
- Principal Investigator
  
  平井誠
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Juntendo University
宿主内環境から迫る、熱帯熱マラリア原虫が急速に薬剤耐性化する機序の解明と治療応用
- Principal Investigator
  
  福田直到
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Juntendo University
マラリア原虫がアルテミシニンに高度耐性化する遺伝的要因を予測する研究Principal Investigator
- Principal Investigator
  
  平井誠
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Juntendo University
マラリア新薬開発と薬剤耐性出現のいたちごっごに終止符を打つ革新的耐性予測マーカー
- Principal Investigator
  
  美田敏宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Juntendo University
アフリカに初めて出現した第一選択薬アルテミシニンへの耐性マラリア：蔓延機序の解明
- Principal Investigator
  
  美田敏宏
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Juntendo University
Clarification of host adaptation mechanisms by using mutator malaria parasitePrincipal Investigator
- Principal Investigator
  
  Hirai Makoto
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Juntendo University
New interactome strategy elucidating the fertilization mechanism of malaria parasite
- Principal Investigator
  
  Mori Toshiyuki
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphology/Structure
- Research Institution
  Osaka University
  Juntendo University
Predicting the emergence of drug-resistant malaria: Development of a comprehensive laboratory evolution system with accelerated evolution system
- Principal Investigator
  
  Mita Toshihiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Juntendo University
Comprehensive elucidation of fitness cost in drug-resistant malaria parasites through while life cycle
- Principal Investigator
  
  Tachibana Shin-Ichiro
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Juntendo University
Method for mutation in organelle genome by CRISPR/CAS9Principal Investigator
- Principal Investigator
  
  HIRAI Makoto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Juntendo University
Development of a new transmission-blocking method against malaria, using rare sugar-containing sugar solution as food for vector mosquitoes
- Principal Investigator
  
  ARAI Meiji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Kagawa University
超加速進化型オルガネラゲノムを持つマラリア原虫の創成と予測進化学への応用Principal Investigator
- Principal Investigator
  
  平井誠
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
マラリア原虫ＧＣＳ１を基盤とした受精メカニズムの解明Principal Investigator
- Principal Investigator
  
  平井誠
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Juntendo University
  Gunma University
Generation of rodent malaria parasite with high mutation rate and confirmation of its usefulness for next generation of malariologyPrincipal Investigator
- Principal Investigator
  
  Makoto Hirai
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Juntendo University
  Gunma University
Identification of mosquito-specific factors which promote growth and differentiation of malaria parasite in the vector mosquito
- Principal Investigator
  
  ARAI Meiji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Kagawa University
Establishment of an experimental model system for a highly accelerated evolution using mutator malaria parasites generated by the disparity mutagenesis
- Principal Investigator
  
  TANABE Kazuyuki
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Osaka University
マラリア原虫配偶子認識・膜融合機構の解明とその普遍性の検証Principal Investigator
- Principal Investigator
  
  平井誠
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
受精決定因子pbgcs1を基軸としたマラリア原虫受精メカニズムの解明Principal Investigator
- Principal Investigator
  
  平井誠
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Gunma University
  Jichi Medical University
Molecular analyses of G6PD variants in malaria endemic areas in Asian and African countries
- Principal Investigator
  
  MATSUOKA Hiroyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
The mechanisms of sexual reproduction of malaria parasitesPrincipal Investigator
- Principal Investigator
  
  HIRAI Makoto
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Jichi Medical University
逆遺伝学的手法によるマラリア原虫生殖母体分化の分子機構解明Principal Investigator
- Principal Investigator
  
  平井誠
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Jichi Medical University
Molecular analysis of G6PD variants in malaria endemic areas
- Principal Investigator
  
  MASTSUOKA Hiroyuki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  Jichi Medical University
How malaria parasites move from the skin to the liver or other organs after injected by mosquitoes?
- Principal Investigator
  
  MATSUOKA Hiroyuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  JICHI MEDICAL SCHOOL
熱帯熱マラリア原虫生殖母体分化の分子機構の解明Principal Investigator
- Principal Investigator
  
  平井誠
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Jichi Medical University
Molecular analysis of G6PD variants in Asian Countries
- Principal Investigator
  
  MATSUOKA Hiroyuki
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  JICHI MEDICAL SCHOOL
Generation of transgenic anopheline mosquitoes refractory to malaria parasite by using gene manipulation
- Principal Investigator
  
  YOSHIDA Shigeto
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Jichi Medical School
MOLECULAR ANALYSIS OF G6PD VARIANTS IN ASIA
- Principal Investigator
  
  MATSUOKA Hiroyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hematology
- Research Institution
  JICHI MEDICAL SCHOOL
STUDIES ON GAMETOCYTA ACTIVATING FACTOR IN THE SALIVARY GRAND OF ANOPHELINE MOSQUITOES
- Principal Investigator
  
  MATSUOKA Hiroyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  寄生虫学(含医用動物学)
- Research Institution
  Jichi Medical School

[Book] Sexual Reproduction in Animals and Plants2014
- Author(s)
  HIRAI M
- Publisher
  Elsevier
- Data Source
  KAKENHI-PUBLICLY-24112705
[Book] [動植物の受精学]　共通機構と多様性2014
- Author(s)
  森稔幸、平井　誠
- Total Pages
  11
- Publisher
  化学同人
- Data Source
  KAKENHI-PUBLICLY-24112705
[Book] 生物の受精2014
- Author(s)
  森稔幸、平井　誠
- Publisher
  化学と生物
- Data Source
  KAKENHI-PROJECT-24590501
[Book] Sexual reproduction2014
- Author(s)
  Makoto Hirai
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-24590501
[Book] 医学のあゆみ第230巻2号(光るマラリア原虫)2009
- Author(s)
  松岡裕之、平井誠
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Isolation of Mutants With Reduced Susceptibility to Piperaquine From a Mutator of the Rodent Malaria Parasite Plasmodium berghei.2021
- Author(s)
  Ikeda M, Hirai M, Tachibana SI, Mori T, Mita T.
- Journal Title
  
  Front Cell Infect Microbiol.
  
  Volume: - Pages: 672691-672691
- DOI
  10.3389/fcimb.2021.672691
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04074, KAKENHI-PROJECT-19K22446, KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-21K06987, KAKENHI-PROJECT-19K16631, KAKENHI-PROJECT-18KK0231, KAKENHI-PROJECT-22KJ2743
[Journal Article] Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in Northern Uganda2021
- Author(s)
  Fukuda N, Tachibana S-I、Ikeda M、Sakurai-Yatsushiro M、Balikagala B、Katuro O、Yamauchi M、Emoto S、Hashimoto M、Yatsushiro S、Sekihara Makoto、et al
- Journal Title
  
  Parasitology International
  
  Volume: 81 Pages: 102277-102277
- DOI
  10.1016/j.parint.2020.102277
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-18KK0231, KAKENHI-PROJECT-17H03707, KAKENHI-PROJECT-17H04074, KAKENHI-PROJECT-19K22446, KAKENHI-PROJECT-21K06987, KAKENHI-PROJECT-20K16238, KAKENHI-PROJECT-21K20765
[Journal Article] Pb103 Regulates Zygote/Ookinete Development in Plasmodium berghei via Double Zinc Finger Domains.2021
- Author(s)
  Hirai M, Maeta A, Mori T and Mita T.
- Journal Title
  
  Pathogens
  
  Volume: 10(12) Issue: 12 Pages: 1536-1536
- DOI
  10.3390/pathogens10121536
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04074, KAKENHI-PROJECT-19K22446, KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-21K06987
[Journal Article] Derivatives of Dictyostelium differentiation-inducing factors suppress the growth of Plasmodium parasites in vitro and in vivo.2021
- Author(s)
  Mita T, Hirai M, Maki Y, Nahar S, Yoshida N, Oshima Y, Kikuchi H, Kubohara Y.
- Journal Title
  
  Biochem Pharmacol
  
  Volume: - Pages: 114834-114834
- DOI
  10.1016/j.bcp.2021.114834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04074, KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-19K07139, KAKENHI-PROJECT-20K07466
[Journal Article] Fitness of sulfadoxine-resistant Plasmodium berghei harboring a single mutation in dihydropteroate synthase (dhps).2021
- Author(s)
  Yamauchi M, Hirai M, Tachibana SI, Mori T, Mita T.
- Journal Title
  
  Acta Trop.
  
  Volume: - Pages: 106049-106049
- DOI
  10.1016/j.actatropica.2021.106049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04074, KAKENHI-PROJECT-19K22446, KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-21K06987, KAKENHI-PROJECT-18KK0231
[Journal Article] Recovery and stable persistence of chloroquine sensitivity in Plasmodium falciparum parasites after its discontinued use in Northern Uganda2020
- Author(s)
  Balikagala Betty、Sakurai-Yatsushiro Miki、Hirai Makoto　 et al
- Journal Title
  
  Malaria Journal
  
  Volume: 19 Issue: 1 Pages: 1-12
- DOI
  10.1186/s12936-020-03157-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-19K22446, KAKENHI-PROJECT-19K16631, KAKENHI-PROJECT-18KK0231, KAKENHI-PROJECT-17H03707, KAKENHI-PROJECT-16K08765, KAKENHI-PROJECT-20K16238, KAKENHI-PROJECT-19K22535, KAKENHI-PROJECT-17H04074
[Journal Article] Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations on the island of New Guinea2020
- Author(s)
  Miotto Olivo、Sekihara Makoto、Tachibana Shin-Ichiro、Yamauchi Masato et al
- Journal Title
  
  PLOS Pathogens
  
  Volume: 16 Issue: 12 Pages: e1009133-e1009133
- DOI
  10.1371/journal.ppat.1009133
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-19K22446, KAKENHI-PROJECT-19K16631, KAKENHI-PROJECT-18KK0231, KAKENHI-PROJECT-17H03707, KAKENHI-PROJECT-17H04074
[Journal Article] Postulated Process of Axoneme Organization in the Male Gametogenesis of Malaria Parasite Plasmodium berghei2020
- Author(s)
  Kubo-Irie Miyoko、Hirai Makoto、Irie Masaru、Mohri Hideo
- Journal Title
  
  Zoological Science
  
  Volume: 38 Issue: 2 Pages: 187-192
- DOI
  10.2108/zs200064
- NAID
  210000163224
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-17H04074
[Journal Article] See-through observation of malaria parasite behaviors in the mosquito vector2019
- Author(s)
  Mori Toshiyuki、Hirai Makoto、Mita Toshihiro
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 1768-1768
- DOI
  10.1038/s41598-019-38529-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-17H03707, KAKENHI-PROJECT-18KK0231, KAKENHI-PROJECT-17H04074
[Journal Article] Rapid selection of sulphadoxine-resistant Plasmodium falciparum and its effect on within-population genetic diversity in Papua New Guinea.2018
- Author(s)
  Mita T, Hombhanje F, Takahashi N, Sekihara M, Yamauchi M, Tsukahara T, Kaneko A, Endo H, Ohashi J. (Corresponding author)
- Journal Title
  
  Scientific reports.
  
  Volume: 8 Issue: 1 Pages: 5565-5565
- DOI
  10.1038/s41598-018-23811-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26305015, KAKENHI-PROJECT-26460515, KAKENHI-PROJECT-17H04074
[Journal Article] Artemisinin-Resistant Plasmodium falciparum with High Survival Rates, Uganda, 2014-20162018
- Author(s)
  Ikeda M, Kaneko M, Tachibana S-I, Balikagala B, Sakurai-Yatsushiro M, Yatsushiro S, Takahashi N, Yamauchi M, Sekihara M, Hashimoto M, Katuro OT, Olia A, Obwoya PS, Auma MA, Anywar DA, Odongo-Aginya EI, Okello-Onen J, Hirai M, Ohashi J, Palacpac NMQ, Kataoka M, Tsuboi T, Kimura E, Horii T, Mita T.
- Journal Title
  
  Emerging Infectious Diseases
  
  Volume: 24 Issue: 4 Pages: 718-726
- DOI
  10.3201/eid2404.170141
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08765, KAKENHI-PROJECT-15K08453, KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-26305015, KAKENHI-PROJECT-26460515
[Journal Article] Lack of significant recovery of chloroquine sensitivity in Plasmodium falciparum parasites following discontinuance of chloroquine use in Papua New Guinea2018
- Author(s)
  Sekihara M, Tachibana S-I, Yamauchi M, Yatsushiro S, Tiwara S, Fukuda N, Ikeda M, Mori T, Hirai M, Hombhanje F, Mita T
- Journal Title
  
  Malaria Journal
  
  Volume: 17 Issue: 1 Pages: 434-434
- DOI
  10.1186/s12936-018-2585-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08765, KAKENHI-PROJECT-18K07095, KAKENHI-PROJECT-17H03707, KAKENHI-PROJECT-26305015, KAKENHI-PROJECT-18KK0231, KAKENHI-PROJECT-17H04074
[Journal Article] Plasmodium Rab5b is secreted to the cytoplasmic face of the tubovesicular network in infected red blood cells together with N-acylated adenylate kinase 22016
- Author(s)
  Ebine K, Hirai M, Sakaguchi M, Yahata K, Kaneko O, Saito-Nakano Y.
- Journal Title
  
  Malar J.
  
  Volume: 15 Issue: 1 Pages: 1377-4
- DOI
  10.1186/s12936-016-1377-4
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26117706, KAKENHI-PROJECT-15K08444, KAKENHI-PROJECT-15K08448, KAKENHI-PROJECT-16K08768
[Journal Article] Mutation tendency of mutator Plasmodium berghei with proofreading-deficient DNA polymerase δ.2016
- Author(s)
  Honma H, Niikura M, Kobayashi F, Horii T, Mita T, Endo H, Hirai M
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 36971-36971
- DOI
  10.1038/srep36971
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-26117706, KAKENHI-PROJECT-15K08449, KAKENHI-PROJECT-15K08451, KAKENHI-PROJECT-15K19089
[Journal Article] Plasmodium falciparum kelch 13: a potential molecular marker for tackling artemisinin-resistant malaria parasites.2016
- Author(s)
  Mita T, Tachibana S, Hashimoto M, Hirai M.
- Journal Title
  
  Expert Rev Anti Infect Ther.
  
  Volume: 14 Issue: 1 Pages: 125-135
- DOI
  10.1586/14787210.2016.1106938
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08452, KAKENHI-PROJECT-15K08453, KAKENHI-PROJECT-24590501, KAKENHI-PUBLICLY-26117706
[Journal Article] Lactate retards the development of erythrocytic stages of the human malaria parasite Plasmodium falciparum.2015
- Author(s)
  Hikosaka K, Hirai M, Komatsuya K, Ono Y, Kita K.
- Journal Title
  
  Parasitol Int
  
  Volume: 64 Issue: 3 Pages: 301-303
- DOI
  10.1016/j.parint.2014.08.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-26860277, KAKENHI-PROJECT-24590501
[Journal Article] Visualization of Malaria Parasites in the Skin Using the Luciferase Transgenic Parasite,<i> Plasmodium berghei</i>2015
- Author(s)
  Matsuoka H, Tomita H, Hattori R, Arai M, Hirai M.
- Journal Title
  
  Trop.Med.Health
  
  Volume: 43 Issue: 1 Pages: 53-61
- DOI
  10.2149/tmh.2014-18
- NAID
  130004704899
- ISSN
  1348-8945, 1349-4147
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590501
[Journal Article] Direct evidence for the atovaquone action on the Plasmodium cytochrome bc1 complex.2015
- Author(s)
  Siregar JE, Kurisu G, Kobayashi T, Matsuzaki M, Sakamoto K, Mi-Ichi F, Watanabe Y, Hirai M, Matsuoka H, Syafruddin D, Marzuki S, Kita K.
- Journal Title
  
  Parasitol Int
  
  Volume: 64 Issue: 3 Pages: 295-300
- DOI
  10.1016/j.parint.2014.09.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24112705, KAKENHI-PUBLICLY-26117719, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-24590501
[Journal Article] Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis2015
- Author(s)
  Taniguchi T, Miyauchi E, Nakamura S, Hirai M, Suzue K, Imai T, Nomura T, Handa T, Okada H, Shimokawa C, Onishi R, Olia A, Hirata J, Tomita H, Ohno H, Horii T, Hisaeda H
- Journal Title
  
  Scientific Reports
  
  Volume: 5:15699 Issue: 1 Pages: 1-12
- DOI
  10.1038/srep15699
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08441, KAKENHI-PROJECT-15K08453, KAKENHI-PROJECT-15K08520, KAKENHI-PROJECT-26870094, KAKENHI-PROJECT-24249024, KAKENHI-PROJECT-15H05274, KAKENHI-PROJECT-13J05482, KAKENHI-PROJECT-24590501, KAKENHI-PROJECT-26850090, KAKENHI-PROJECT-26860276
[Journal Article] Generation of rodent malaria parasites with a high mutation rate by destructing proofreading activity of DNA polymerase δ.2014
- Author(s)
  Honma H, Hirai M, Nakamura S, Hakimi H, Kawazu S, Palacpac NM, Hisaeda H, Matsuoka H, Kawai S, Endo H, Yasunaga T, Ohashi J, Mita T, Horii T, Furusawa M, Tanabe K.
- Journal Title
  
  DNA Res
  
  Volume: 21 Issue: 4 Pages: 439-46
- DOI
  10.1093/dnares/dsu009
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-24590501, KAKENHI-PROJECT-25670226
[Journal Article] Evaluating experimental cerebral malaria using oxidative stress indicator OKD48 mice.2014
- Author(s)
  Imai T, Iwawaki T, Akai R, Suzue K, Hirai M, Taniguchi T, Okada H, Hisaeda H.
- Journal Title
  
  Int J Parasitol.
  
  Volume: 44 Issue: 10 Pages: 681-685
- DOI
  10.1016/j.ijpara.2014.06.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-24590501, KAKENHI-PROJECT-25670226, KAKENHI-PROJECT-26860276, KAKENHI-PROJECT-26870094
[Journal Article] Resistance to Malaria by Enhanced Phagocytosis of Erythrocytes in LMP7-deficient Mice.2013
- Author(s)
  Duan X, Imai T, Chou B, Tu L, Himeno K, Suzue K, Hirai M, Taniguchi T, Okada H, Shimokawa C, Hisaeda H.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 3 Pages: 1-9
- DOI
  10.1371/journal.pone.0059633
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-24590501, KAKENHI-PROJECT-24790399, KAKENHI-PUBLICLY-24117504
[Journal Article] Characterazation of burdock mottle virus, a novel member of the genus Benyvirus, and the presence of benyvirus-related sequences in the plant and insect genomes.2013
- Author(s)
  Kondo, H. , Hirano, S., Chiba, S., Andika, I.B., Hirai, M., Maeda, T. and Tamada, T.
- Journal Title
  
  Virus Research
  
  Volume: 177 Issue: 1 Pages: 75-86
- DOI
  10.1016/j.virusres.2013.07.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24580064, KAKENHI-PROJECT-24590501
[Journal Article] IL-23 protection against Plasmodium berghei infection in mice is partially dependent on IL-17 from macrophages2013
- Author(s)
  Ishida H, Imai T, Suzue K, Hirai M, Taniguchi T, Yoshimura A, Iwakura Y, Okada H, Suzuki T, Shimokawa C, and Hisaeda
- Journal Title
  
  Eur. J. Immunol.
  
  Volume: 43 Issue: 10 Pages: 2696-2706
- DOI
  10.1002/eji.201343493
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117504, KAKENHI-PROJECT-24220011, KAKENHI-PROJECT-24590501, KAKENHI-PROJECT-24790399, KAKENHI-PROJECT-25670226
[Journal Article] Species-specific immunity induced by infection with Entamoeba histolytica and Entamoeba moshkovskii in mice2013
- Author(s)
  Shimokawa, C., Culleton, R., Imai, T., Suzue, K., Hirai, M., Taniguchi, T., Kobayashi, S., Hisaeda, H., Hamano, S
- Journal Title
  
  PLoS One
  
  Volume: 8(11) Issue: 11 Pages: e82025-e82025
- DOI
  10.1371/journal.pone.0082025
- NAID
  120006986684
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23406009, KAKENHI-PUBLICLY-24117504, KAKENHI-PROJECT-24590501, KAKENHI-PROJECT-24590511, KAKENHI-PROJECT-24790399, KAKENHI-PROJECT-25670226
[Journal Article] CD8(+) T cell activation by murine erythroblasts infected with malaria parasites.2013
- Author(s)
  Imai T, Ishida H, Suzue K, Hirai M, Taniguchi T, Okada H, Suzuki T, Shimokawa C, Hisaeda H.
- Journal Title
  
  Sci Rep.
  
  Volume: 3 Issue: 1 Pages: 1572-1572
- DOI
  10.1038/srep01572
- NAID
  120006985954
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-24590501, KAKENHI-PROJECT-24790399, KAKENHI-PUBLICLY-24117504
[Journal Article] Toward understanding the role of mitochondrial complex II in the intraerythrocytic stages of Plasmodium falciparum: gene targeting of the Fp subunit.2012
- Author(s)
  Tanaka TQ, Hirai M, Watanabe Y, Kita K.
- Journal Title
  
  Parasitol Int
  
  Volume: 61 Issue: 4 Pages: 726-8
- DOI
  10.1016/j.parint.2012.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-24590501, KAKENHI-PUBLICLY-24117504
[Journal Article] One Injection of DsRed Followed by Bites from Transgenic Mosquitoes Producing DsRed in the Saliva Elicits a High Titer of Antibody in Mice2012
- Author(s)
  Matsuoka H, Sano G, Hattori R, Tomita H, Yamamoto DS, Hirai M.
- Journal Title
  
  Trop.Med.Health
  
  Volume: 40 Issue: 2 Pages: 47-53
- DOI
  10.2149/tmh.2011-10
- NAID
  10031123157
- ISSN
  1348-8945, 1349-4147
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-24590501
[Journal Article] Critical roles of the mitochondrial complex II in oocyst formation of rodent malaria parasite Plasmodium berghei.2012
- Author(s)
  Hino A, Hirai M, Tanaka TQ, Watanabe Y, Matsuoka H, Kita K.
- Journal Title
  
  J Biochem
  
  Volume: 152 Issue: 3 Pages: 259-68
- DOI
  10.1093/jb/mvs058
- NAID
  10031166137
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-24590501, KAKENHI-PUBLICLY-24117504
[Journal Article] A critical role for phagocytosis in resistance to malaria in iron-deficient mice2011
- Author(s)
  Matsuzaki-Moriya C, Tu L, Ishida H, Imai T, Suzue K, Hirai M, Tetsutani K, Hamano S, Shimokawa C, Hisaeda H
- Journal Title
  
  Eur J Immunol
  
  Volume: 41 Pages: 1365-75
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22112519
[Journal Article] A new glucose-6-phosphate dehydrogenase deficiency variant, G6PD Mizushima, showing increases in serum ferritin and cytosol leucine aminopeptidase levels.2011
- Author(s)
  Suga Y, Nagita A, Takesako R, Tanaka I, Kobayashi K, Hirai M, Matsuoka H
- Journal Title
  
  J Pediatr Hematol Oncol 33(1)
  
  Pages: 15-17
- Data Source
  KAKENHI-PROJECT-20406023
[Journal Article] Clues to Evolution of the SERA Multigene Family in 18 Plasmodium Species.2011
- Author(s)
  Arisue N, Kawai S, Hirai M, Palacpac NM, Jia M, Kaneko A, Tanabe K, Horii T.
- Journal Title
  
  PLoS One
  
  Volume: vol.6
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22112519
[Journal Article] Clues to Evolution of the SERA Multigene Family in 18 Plasmodium Species.2011
- Author(s)
  Arisue N, Kawai S, Hirai M, Palacpac NM, Jia M, Kaneko A , Tanabe K, Horii T.
- Journal Title
  
  PLoS One
  
  Volume: vol.6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Clues to Evolution of the SERA Multigene Family in 18 Plasmodium Species.2011
- Author(s)
  Arisue N, Kawai S, Hirai M, Palacpac NM, Jia M, Kaneko A, Tanabe K, Horii T.
- Journal Title
  
  PLoS One. vol.6,No3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Clues to Evolution of the SERA Multigene Family in 18 Plasmodium Species.2011
- Author(s)
  Arisue N, Kawai S, Hirai M, Palacpac NM, Jia M, Kaneko A, Tanabe K, Horii T.
- Journal Title
  
  PLoS One
  
  Volume: vol.6
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022044
[Journal Article] Fertilization is a novel attacking site for the transmission blocking of malaria parasites.2010
- Author(s)
  Hirai M, Mori T.
- Journal Title
  
  Acta Trop
  
  Volume: vol.114 Pages: 157-161
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022044
[Journal Article] Fertilization is a novel attacking site for the transmission blocking of malaria parasites.2010
- Author(s)
  Hirai M, Mori T.
- Journal Title
  
  Acta Trop
  
  Volume: vol.114 Pages: 157-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] The functional domain of GCS1-based gamete fusion resides in the amino terminus in plant and parasite species.2010
- Author(s)
  Mori T, Hirai M, Kuroiwa T, Miyagishima SY.
- Journal Title
  
  PLoS One
  
  Volume: vol.5
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22112519
[Journal Article] Evaluation of a loop-mediated isothermal amplification method as a tool for diagnosis of infection by the zoonotic simian malaria parasite Plasmodium knowlesi.2010
- Author(s)
  Iseki H, Kawai S, Takahashi N, Hirai M, Tanabe K, Yokoyama N, Igarashi I.
- Journal Title
  
  J Clin Microbiol.
  
  Volume: vol.48 Pages: 2509-14
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022044
[Journal Article] Development of experimental cerebral malaria is independent of IL-23 and IL-17.2010
- Author(s)
  Ishida H, Matsuzaki-Moriya C, Imai T, Yanagisawa K, Nojima Y, Suzue K, Hirai M, Iwakura Y, Yoshimura A, Hamano S, Shimokawa C, Hisaeda H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: Vol.402 Pages: 790-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] The functional domain of GCS1-based gamete fusion resides in the amino terminus in plant and parasite species.2010
- Author(s)
  Mori T, Hirai M, Kuroiwa T, Miyagishima SY.
- Journal Title
  
  PLoS One vol.5,No12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] The functional domain of GCS1-based gamete fusion resides in the amino terminus in plant and parasite species.2010
- Author(s)
  Mori T, Hirai M, Kuroiwa T, Miyagishima SY.
- Journal Title
  
  PLoS One
  
  Volume: vol.5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] The first case of a class I glucose-6-phosphate dehydrogenase deficiency, G6PD Santiago de Cuba (1339 G>A), in a Chinese population as found in a survey for G6PD deficiency in northeastern and central China.2010
- Author(s)
  Wang J, Matsuoka H, Hirai M, Mu L, Yang L, Luo E.
- Journal Title
  
  Acta Med Okayama
  
  Volume: vol.64 Pages: 49-54
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22112519
[Journal Article] The first case of a class I glucose-6-phosphate dehydrogenase deficiency, G6PD Santiago de Cuba (1339 G>A), in a Chinese population as found in a survey for G6PD deficiency in northeastern and central China.2010
- Author(s)
  Wang J, Matsuoka H, Hirai M, Mu L, Yang L, Luo E
- Journal Title
  
  Acta Med Okayama
  
  Volume: vol.64 Pages: 49-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Development of experimental cerebral malaria is independent of IL-23 and IL-17.2010
- Author(s)
  Ishida H, Matsuzaki-Moriya C, Imai T, Yanagisawa K, Nojima Y, Suzue K, Hirai M, Iwakura Y, Yoshimura A, Hamano S, Shimokawa C, Hisaeda H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: Vol.402 Pages: 790-795
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022044
[Journal Article] The first case of a class I glucose-6-phosphate dehydrogenase deficiency, G6PD Santiago de Cuba (1339 G>A), from Chinese population as found in a survey for G6PD deficiency in northeastern and central China.2010
- Author(s)
  Wang J, Matsuoka H, Hirai M, Mu L, Yang L, Luo E.
- Journal Title
  
  Acta Med Okayama 64(1)
  
  Pages: 49-54
- Data Source
  KAKENHI-PROJECT-20406023
[Journal Article] Development of experimental cerebral malaria is independent of IL-23 and IL-17.2010
- Author(s)
  Ishida H, Matsuzaki-Moriya C, Imai T, Yanagisawa K, Nojima Y, Suzue K, Hirai M, Iwakura Y, Yoshimura A, Hamano S, Shimokawa C, Hisaeda H.
- Journal Title
  
  Biochem Biophys Res Commun. Vol.402,No.4
  
  Pages: 790-795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Production of a transgenic mosquito expressing circumsporozoite protein, a malarial protein, in the salivary gland of Anopheles stenhensi (Dintera : Culicidae).2010
- Author(s)
  Matsuoka H, Ikezawa T, Hirai M.
- Journal Title
  
  Acta Med Okayama
  
  Volume: vol.64 Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Fertilization is a novel attacking site for the transmission blocking of malaria parasites.2010
- Author(s)
  Hirai M, Mori T.
- Journal Title
  
  Acta Trop
  
  Volume: vol.114 Pages: 157-161
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22112519
[Journal Article] Fertilization is a novel attacking site for the transmission blocking of malaria parasites.2010
- Author(s)
  Hirai M, Mori T.
- Journal Title
  
  Acta Trop vol.114,No.3
  
  Pages: 157-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] The first case of a class I glucose-6-phosphate dehydrogenase deficiency, G6PD Santiago de Cuba (1339 G>A), in a Chinese population as found in a survey for G6PD deficiency in northeastern and central China.2010
- Author(s)
  Wang J, Matsuoka H, Hirai M, Mu L, Yang L, Luo E.
- Journal Title
  
  Acta Med Okayama
  
  Volume: vol.64 Pages: 49-54
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022044
[Journal Article] The first case of a class I glucose-6-phosphate dehydrogenase deficiency, G6PD Santiago de Cuba (1339 G>A), in a Chinese population as found in a survey for G6PD deficiency in northeastern and central China.2010
- Author(s)
  Wang J, Matsuoka H, Hirai M, Mu L, Yang L, Luo E.
- Journal Title
  
  Acta Med Okayama vol.64,No.1
  
  Pages: 49-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Production of a transgenic mosquito expressing circumsporozoite protein, a malarial protein, in the salivary gland of Anopheles stephensi (Diptera : Culicidae).2010
- Author(s)
  Matsuoka H, Ikezawa T, Hirai M
- Journal Title
  
  Acta Med Okayama
  
  Volume: vol.64 Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22112519
[Journal Article] Development of experimental cerebral malaria is independent of IL-23 and IL-17.2010
- Author(s)
  Ishida H, Matsuzaki-Moriya C, Imai T, Yanagisawa K, Nojima Y, Suzue K, Hirai M, Iwakura Y, Yoshimura A, Hamano S, Shimokawa C, Hisaeda H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: Vol.402 Pages: 790-795
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22112519
[Journal Article] Fertilization is a novel attacking site for the transmission blocking of malaria parasites2010
- Author(s)
  Hirai M, Mori T
- Journal Title
  
  Acta Tropica 114
  
  Pages: 157-161
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022044
[Journal Article] The functional domain of GCS1-based gamete fusion resides in the amino terminus in plant and parasite species.2010
- Author(s)
  Mori T, Hirai M, Kuroiwa T, Miyagishima SY.
- Journal Title
  
  PLoS One
  
  Volume: vol.5
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022044
[Journal Article] Fertilization is a novel attacking site for the transmission blocking of malaria parasites2010
- Author(s)
  Hirai M, Mori T
- Journal Title
  
  Acta Tropica 114
  
  Pages: 157-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Production of a transgenic mosquito expressing circumsporozoite protein, a malarial protein, in the salivary gland of Anopheles stephensi (Diptera : Culicidae).2010
- Author(s)
  Matsuoka H, Ikezawa T, Hirai M
- Journal Title
  
  Acta Med Okayama
  
  Volume: vol.64 Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022044
[Journal Article] Production of a transgenic mosquito expressing circumsporozoite protein, a malarial protein, in the salivary gland of Anopheles stephensi (Diptera: Culicidae).2010
- Author(s)
  Matsuoka H, Ikezawa T, Hirai M
- Journal Title
  
  Acta Med Okayama. vol.64,No.4
  
  Pages: 233-241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Evaluation of a loop-mediated isothermal amplification method as a tool for diagnosis of infection by the zoonotic simian malaria parasite Plasmodium knowlesi.2010
- Author(s)
  Iseki H, Kawai S, Takahashi N, Hirai M, Tanabe K, Yokoyama N, IRarashi I.
- Journal Title
  
  J Clin Microbiol.
  
  Volume: vol.48 Pages: 2509-2514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Evaluation of a loop-mediated isothermal amplification method as a tool for diagnosis of infection by the zoonotic simian malaria parasite Plasmodium knowlesi.2010
- Author(s)
  Iseki H, Kawai S, Takahashi N, Hirai M, Tanabe K, Yokoyama N, Igarashi I.
- Journal Title
  
  J Clin Microbiol.
  
  Volume: vol.48 Pages: 2509-14
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22112519
[Journal Article] Evaluation of a loop-mediated isothermal amplification method as a tool for diagnosis of infection by the zoonotic simian malaria parasite Plasmodium knowlesi.2010
- Author(s)
  Iseki H, Kawai S, Takahashi N, Hirai M, Tanabe K, Yokoyama N, Igarashi I.
- Journal Title
  
  J Clin Microbiol. vol.48,No.7
  
  Pages: 2509-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Cross-reactivity in rapid diagnostic tests between human malaria and zoonotic simian malaria parasite Plasmodium knowlesi infections.2009
- Author(s)
  Kawai S, Hirai M, Haruki K, Tanabe K, Chigusa Y.
- Journal Title
  
  Parasitol Int. vol.58,No.3
  
  Pages: 300-2
- NAID
  10027669975
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] 光るマラリア原虫2009
- Author(s)
  松岡裕之、平井誠
- Journal Title
  
  医学のあゆみ 230
  
  Pages: 153-157
- Data Source
  KAKENHI-PUBLICLY-21022044
[Journal Article] The Plasmodium HU homolog, which binds the plastid DNA sequence-independently, is essential for the parasite's survival2009
- Author(s)
  Sasaki N, Hirai M, et al
- Journal Title
  
  FEBS Letters 583
  
  Pages: 1446-1450
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21022044
[Journal Article] 光るマラリア原虫2009
- Author(s)
  松岡裕之, 平井誠
- Journal Title
  
  医学のあゆみ 230
  
  Pages: 153-157
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] The Plasmodium HU homolog, which binds the plastid DNA sequence-independent manner, is essential for the parasite's survival.2009
- Author(s)
  Sasaki N, Hirai M, Maeda K, Yui R, Itoh K, Namiki S, Morita T, Hata M, Murakami-Murofushi K, Matsuoka H, Kita K, Sato S.
- Journal Title
  
  FEBS Lett. vol.583,No.9
  
  Pages: 1446-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] The Plasmodium HU homolog, which binds the plastid DNA sequence-independently, is essential for the parasite's survival2009
- Author(s)
  Sasaki N, Hirai M, et al
- Journal Title
  
  FEBS Letters 583
  
  Pages: 1446-1450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Nine different glucose-6-phosphate dehydrogenase (G6PD)variants in a Malaysian population with Malay, Chinese, Indian and Orang Asli (Aboriginal Malaysian)backgrounds2008
- Author(s)
  Wang J, Luo E, Hirai M, Arai M, Abdul-Manan EAS, Mohamed-Isa Z, Hidayah NI, Matsuoka H
- Journal Title
  
  Acta Medica Okayama 53
  
  Pages: 327-332
- NAID
  120002305207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20406023
[Journal Article] Male fertility of malaria parasite is determined by GCS, a plant-typereproduction factor2008
- Author(s)
  平井誠
- Journal Title
  
  Current Biology 18
  
  Pages: 607-613
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Nine different glucose-6-phosphate dehydrogenase (G6PD) variants in a Malaysian population with Malay, Chinese, Indian and Orang Asli (Aboriginal Malaysian) backgrounds.2008
- Author(s)
  Wang J, Luo E, Hirai M, Arai M, Abdul-Manan EAS, Mohamed-Isa Z, Hidayah NI, Matsuoka H
- Journal Title
  
  Acta Med Okayama 62(5)
  
  Pages: 327-332
- NAID
  120002305207
- Data Source
  KAKENHI-PROJECT-20406023
[Journal Article] Male fertility of malaria parasites is determined by GCS1, a plant-type reproduction factor.2008
- Author(s)
  Hirai M, Arai M, Mori T, Miyagishima SY, Kawai S, Kita K, Kuroiwa T, Terenius O, Matsuoka H.
- Journal Title
  
  Curr Biol. vol.18,No.8
  
  Pages: 607-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590426
[Journal Article] Seven Different glucose-6-phosphate dehydrogenase variants including a new variant Distributed in Lam Dong Province in Southern Vietnam2007
- Author(s)
  Matsuoka, H., Thuan, DT., van Thien, H., Kanbe, T., Jalloh, A., Hirai, M., Arai, M., Dung, NT., Kawamoto, F
- Journal Title
  
  Acta Medica Okayama 61
  
  Pages: 213-219
- NAID
  120002311541
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17406025
[Journal Article] Seven Different glucose-6-phosphate dehydrogenase variants including a new variant Distributed in Lam Dong Province in Southern Vietnam2007
- Author(s)
  Matsuoka H, Thuan DT, van Thien H, Kanbe T, Jalloh A, Hirai M, Arai M, Dung NT, Kawamoto F
- Journal Title
  
  Acta Medica Okayama 61
  
  Pages: 213-219
- NAID
  120002311541
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17406025
[Journal Article] Seven Different glucose-6-phosphate dehydrogenase variants including a new variant Distributed in Lam Dong Province in Southern Vietnam2007
- Author(s)
  Matsuoka H, Thuan DTV, van Thien H, Kanbe T, Jalloh A, Hirai M, Arai M, Dung NT, Kawamoto F
- Journal Title
  
  Acta Medica Okayama (In press)
- NAID
  120002311541
- Data Source
  KAKENHI-PROJECT-17406025
[Journal Article] PbGCbeta is essential for Plasmodium ookinete motility to invade midgut cell and for successful completion of parasite life cycle in mosquitoes2006
- Author(s)
  Hirai M, Arai M, Kawai S, Matsuoka H
- Journal Title
  
  Journal of Biochemistry 140・5
  
  Pages: 747-757
- Data Source
  KAKENHI-PROJECT-17790279
[Journal Article] Glucose-6-phosphate dehydrogenase(G6PD) mutations in Cambodia: G6PD Viangchan(871G>A) is the most common variant in the Cambodian population2005
- Author(s)
  Matsuoka H, Nguon C, Kanbe T, Jalloh A, Sato H, Yoshida S, Hirai H, Arai M, Socheat D, Kawamoto F
- Journal Title
  
  Journal of Human Genetics 50
  
  Pages: 469-472
- NAID
  40006922939
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17406025
[Journal Article] Glucose-6-phosphate dehydrogenase(G6PD) mutations in Cambodia : G6PD Viangchan(871G>A) is the most common variant in the Cambodian population.2005
- Author(s)
  Matsuoka H, Nguon C, Kanbe T, Jalloh A, Sato H, Yoshida S, Hirai H, Arai M, Socheat D, Kawamoto F.
- Journal Title
  
  Journal of Human Genetics 50(9)
  
  Pages: 468-472
- NAID
  40006922939
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590344
[Journal Article] Glucose-6-phosphate dehydrogenase (G6PD) mutations in Cambodia : G6PD Viangchan (871G>A) is the most common variant in the Cambodian population.2005
- Author(s)
  Matsuoka H, Nguon C, Kanbe T, Jalloh A, Sato H, Yoshida S, Hirai M, Arai M, Socheat D, Kawamoto F.
- Journal Title
  
  J Hum Genet. 50・9
  
  Pages: 468-472
- Data Source
  KAKENHI-PROJECT-17790279
[Journal Article] Glucose-6-phosphate dehydrogenase (G6PD) mutations in Cambodia : G6PD Viangchan (871G>A) is the most common variant in the Cambodian population2005
- Author(s)
  Matsuoka H, Nguon C, Kanbe T, Jalloh A, Sato H, Yoshida S, Hirai H, Arai M, Socheat D, Kawamoto F
- Journal Title
  
  Jounal of Human Geneics 50(9)
  
  Pages: 468-472
- NAID
  40006922939
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590344
[Journal Article] Glucose-6-phosphate dehydrogenase (G6PD) mutations in Cambodia : G6PD Viangchan (871G>A) is the most common variant in the Cambodian population2005
- Author(s)
  Matsuoka H, Nguon C, Kanbe T, Jalloh A, Sato H, Yoshida S, Hirai H, Arai M, Socheat D, Kawamoto F
- Journal Title
  
  Journal of Human Genetics 50(9)
  
  Pages: 469-472
- NAID
  40006922939
- Data Source
  KAKENHI-PROJECT-17406025
[Journal Article] Cloning, expression and phylogenetic analysis of Hemolin, from the Chinese oak silkmoth, Antheraea pernyi.2005
- Author(s)
  Li W, Terenius O, Hirai M, Nilsson AS, Faye I.
- Journal Title
  
  Dev Comp Immunol. 29・10
  
  Pages: 853-864
- Data Source
  KAKENHI-PROJECT-17790279
[Journal Article] Glucose-6-phosphate dehydrogenase(G6PD) mutations in Cambodia : G6PD Viangchan(871G>A) is the most common variant in the Cambodian population2005
- Author(s)
  Matsuoka, H., Nguon, C., Kanbe, T., Jalloh, A., Sato, H., Yoshida, S., Hirai, H., Arai, M., Socheat, D., Kawamoto, F
- Journal Title
  
  Journal of Human Genetics 50
  
  Pages: 469-472
- NAID
  40006922939
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17406025
[Journal Article] Glucose-6-phosphate dehydrogenase (G6PD) mutations in Myanmar : G6PD Mahidol (487G>A) is the most common variant in the Myanmar population.2004
- Author(s)
  Matsuoka H, Wang J, Hirai M, Arai M, Yoshida S, Kobayashi T, Jalloh A, Lin K, Kawamoto F.
- Journal Title
  
  J Hum Genet 49(10)
  
  Pages: 544-547
- NAID
  10013797666
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14406026
[Journal Article] Two cases of glucose-6-phophate dehydrogenase deficient Nepalese belonging to the G6PD Mediterranean-type, not India-Pakistan sub-type but Mediterranean-Middle East sub-type.2003
- Author(s)
  Matsuoka H, Jichun W, Hirai M, Yoshida S, Arai M, Ishii A, Baral MP.
- Journal Title
  
  J Hum Genet 48(5)
  
  Pages: 275-277
- NAID
  10011594852
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14406026
[Presentation] Characterization of the mutant with the reduced susceptibility to piperaquine from roden malaria parasite, Plasmodium berghei2023
- Author(s)
  Hayamichi Soki, Ayako Uchida, Meiji Arai, Rie Kubota, Naoaki Shinzawa, Toshihiro Mita and Makoto Hirai
- Organizer
  日本寄生虫学会
- Data Source
  KAKENHI-PROJECT-18K07095
[Presentation] マラリア原虫の適応度決定因子の探索2022
- Author(s)
  丹沢華子、美田敏宏、平井誠
- Organizer
  第91回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19658
[Presentation] 第2世代ネズミマラリアミューテーターから単離したピペラキン感受性低下変異体のSNPs解析2022
- Author(s)
  早道奏喜、内田絢子、美田敏宏、平井誠
- Organizer
  第81回日本寄生虫学会東日本支部大会・日本共生生物学会第6回大会合同大会
- Data Source
  KAKENHI-PROJECT-22K19658
[Presentation] 第2世代ネズミマラリアミューテーターから単離したピペラキン感受性低下変異体のSNPs解析2022
- Author(s)
  早道奏喜、内田絢子、美田敏宏、平井誠
- Organizer
  第91回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-22K19658
[Presentation] パプアニューギニアにおけるKelch 13 C580Y変異熱帯熱マラリア原虫の出現と現状2021
- Author(s)
  吉田菜穂子、山内祐人、森川瞭介、宋書馨、平井誠、美田敏宏
- Organizer
  第90回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] ネズミマラリア原虫Kelch13のインターラクトーム解析2021
- Author(s)
  平井誠、森稔幸、美田敏宏
- Organizer
  第90回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] アルテミシニン耐性マーカーKelch13 ネズミマラリア原虫オルソログの機能解析2020
- Author(s)
  平井誠、森稔幸、美田敏宏
- Organizer
  日本寄生虫学会
- Data Source
  KAKENHI-PROJECT-18K07095
[Presentation] アルテミシニン耐性マーカーKelch13 ネズミマラリア原虫オルソログの機能解析2020
- Author(s)
  平井誠、森稔幸、美田敏宏
- Organizer
  第89回日本寄生虫学会誌上大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] 赤痢アメーバミューテーターを利用したミルテフォシン耐性株の迅速単離と全ゲノム解析による耐性遺伝子変異の同定2020
- Author(s)
  中野由美子、泉山信司、平井誠、川野哲郎
- Organizer
  日本寄生虫学会
- Data Source
  KAKENHI-PROJECT-18K07095
[Presentation] ビオチン化によって同定された、マラリア原虫メス側受精因子2020
- Author(s)
  森稔幸、平井誠、美田敏宏
- Organizer
  第89回日本寄生虫学会誌上大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] パプアニューギニアに出現した K13 C580Y 変異熱帯熱マラリア原虫の集団ゲノム解析2020
- Author(s)
  美田敏宏、関原誠、橘真一郎、山内祐人、ロベルトアマト、ソムヤメーラ、池田美恵、森稔幸、平井誠、バリーアリサ、大橋順、フランシスホンバンジェ、ミオットーオリボ
- Organizer
  日本寄生虫学会
- Data Source
  KAKENHI-PROJECT-18K07095
[Presentation] 蚊-マウスモデルにおけるサルファドキシン耐性マラリア原虫の適応度に関する研究2019
- Author(s)
  山内祐人・平井誠・橘真一郎・森稔幸・美田敏宏
- Organizer
  第88回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-16K08765
[Presentation] 蚊-マウスモデルにおけるサルファドキシン耐性マラリア原虫の適応度に関する研究2019
- Author(s)
  山内祐人, 平井誠, 橘慎一郎, 森稔幸, 美田敏宏
- Organizer
  第88回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] Synthetic biotin ligase enables to label surface invasion factors of cultured human malaria parasite, Plasmodium falciparum2019
- Author(s)
  Ochiai S, Hirai M, Mita T, MOri T.
- Organizer
  Annual meeting of Americal Society of Tropical Medicine and Hygiene
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07095
[Presentation] Emergence of artemisinin-resistant P. falciparum with kelch13 C580Y mutations on the island of New Guinea.2019
- Author(s)
  Miotto O, Sekihara M, Tachibana S, Yamauchi M, Pearson R, Amato R, Goncalves S, Somya M, Noviyanti R, Marfurt J, Auburn S, Price R, Mueller I, Ikeda M, Mori T, Hirai M, Tavul L, Hetzel M, Laman M, Barry A, Ringwald P, Ohashi J, Hombhanje F, Kwiatkowski D, Mita T
- Organizer
  American Society of Tropical Medicine and Hygiene Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] ウガンダ北部マラリア原虫集団におけるアルテミシニン耐性レベルの推移2019
- Author(s)
  池田美恵 , 金子恵 , 橘真一郎 , 山内祐人 , バリカガラベティ, 江本桜子 , 福田直到 , 牧喜子, 森稔幸 , 平井誠 , 橋本宗明 , カツロオスベルト , アウママリー, アニワーデニス , バラクパックニリアン, 片岡正俊, アギニアエマニュエル, 木村英作, 堀井俊宏 , 美田敏宏
- Organizer
  第88回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] In-vivo artemisinin resistance may have emerged in Uganda2019
- Author(s)
  Betty Balikagala, 池田美恵, 橘真一郎, 山内祐人, 福田直到, 関原誠, 江本桜子, Osbert T. Katuro, Opio Walter・Mary Auma, Denis A. Anywar, 森稔幸, 平井誠, 片岡正俊, Nirianne M. Q. Palacpac, Emmanuel I. Odongo-Aginya, 木村英作, 堀井俊宏, 美田敏宏
- Organizer
  第88回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-16K08765
[Presentation] ビオチン化を用いた、新規マラリア原虫赤血球侵入関連因子の探索2019
- Author(s)
  落合紗雪、前田樹里、平井誠、美田敏宏、森稔幸
- Organizer
  第88回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] Synthetic biotin ligase enables to label surface invasion factors of cultured human malaria parasite, Plasmodium falciparum.2019
- Author(s)
  Ochiai S, Maeda J, Hirai M, Mita T, Mori T.
- Organizer
  68th Annual Meeting, Maryland USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] ビオチン化を利用した、マラリア原虫新規受精因子の探索2019
- Author(s)
  森稔幸、平井誠、美田敏宏
- Organizer
  第88回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H03707
[Presentation] Synthetic biotin ligase enables to label surface invasion factors of cultured human malaria parasite, Plasmodium falciparum2019
- Author(s)
  Ochiai S, Maeda J, Hirai M, Mita T, Mori T
- Organizer
  66th ASTMH
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03707
[Presentation] ウガンダ北部マラリア原虫集団におけるアルテミシニン耐性レベルの推移2019
- Author(s)
  池田美恵, 金子恵, 橘真一郎, 山内祐人, Betty Balikagala, 江本桜子, 福田直到, 牧喜子, 森稔幸, 平井誠, 橋本宗明, Osbert T. Katuro, Mary Auma, Denis A. Anywar, Nirianne M. Q. Palacpac, 片岡正俊, Emmanuel I. Odongo-Aginya, 木村英作, 堀井俊宏, 美田敏宏
- Organizer
  第88回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-16K08765
[Presentation] Emergence of artemisinin-resistant Plasmodium falciparum with kelch13 C580Y mutations in Papua New Guinea2019
- Author(s)
  Miotto O, Sekihara M, Tachibana S-I, Yamauchi M, Ikeda M, Mori T, Hirai M, Pearson R, Amato R, Goncalves S, Mueller I, Barry A, Noviyanti R, Ringwald P, Ohashi J, Hombhanje F, Kwiatkowski D, Mita T
- Organizer
  American Society of Tropical Medicine and Hygiene 68th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08765
[Presentation] ビオチン化を利用した、マラリア原虫新規受精因子の探索2019
- Author(s)
  森稔幸、平井誠、美田敏宏
- Organizer
  第88回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] In-vivo artemisinin resistance may have emerged in Uganda,2019
- Author(s)
  バリカガラベテイ , 池田美恵 , 橘真一郎 , 山内祐人 , 福田直到 , 関原誠 , 江本桜子 , Katuro Osbert T., Opio Walter, Auma Mary , Anywar Denis A. , 森稔幸 ,平井誠 , 片岡正俊 , Palacpac Nirianne M.Q. , Odongo-Aginya Emmanuel I., 木村英作 , 堀井俊宏 , 美田敏宏
- Organizer
  第88回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] Detection of Artemisinin-resistant Plasmodium falciparum with High Survival Rates in Uganda2018
- Author(s)
  Mita T. Ikeda M. Kaneko M. Tachibana S. Balikagala B. Sakurai-Yatsushiro M. Yatsushiro S. Takahashi N. Yamauchi M. Sekihara M. Hashimoto M. Obwoya PS. Auma MA. Anywar DA. Odongo-Aginya EI. Hirai M. Ohashi J. Palacpac NMQ. Kataoka M. Tsuboi T. Kimura E.andHorii T
- Organizer
  14th International congress of parastiology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] 希少糖含有シロップによるマラリア伝播阻止効果の検討2018
- Author(s)
  新井明治, 平井誠, 田中健Q, 徳田雅明, 何森健
- Organizer
  第87回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-15K15123
[Presentation] ウガンダにおけるin vivo薬剤耐性試験およびRSAを用いたアルテミシニン耐性疫学調査.2017
- Author(s)
  池田美恵, 橘真一郎, 山内祐人, Auma M, 関原誠, 森稔幸, 平井誠, Palacpac N, 木村英作, Aginya E, 堀井俊宏, 美田敏宏.
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] Prerequisite Emergence of Background Mutations For Kelch13-Related Artemisinin-Resistant Plasmodium Falciparum Isolates.2017
- Author(s)
  Tachibana S-I, Mori T, Hirai M, Mita T
- Organizer
  American Society of Tropical Medicine and Hygiene 66th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] Isolation of Piperaquine Resistant Rodent Malaria Parasite from Mutator Malaria.2017
- Author(s)
  Hirai M, Ikeda M, Tachibana S-I, Mita T
- Organizer
  American Society of Tropical Medicine and Hygiene 66th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] Isolation of piperaquine-resistant rodent malaria parasite from malaria mutator2017
- Author(s)
  Hirai M, Ikeda M, Tachibana S-I, Mita T
- Organizer
  American Society of Tropical Medicine and Hygiene 66th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08765
[Presentation] 宿主内競争による熱帯熱マラリア原虫のクロロキン感受性の回復.2017
- Author(s)
  橘真一郎, 池田美恵, Balikagala B, 櫻井美樹, 八代聖基, 関原誠, 山内祐人, Auma MA, 平井誠, 森稔幸, Palacpac N, 片岡正俊, 木村英作, 堀井俊宏, 美田敏宏.
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] 希少糖D-アロースはハマダラカ体内でマラリア原虫の発育分化を阻害する2017
- Author(s)
  新井明治, 平井誠, 田中健Q, 寺中正人, 徳田雅明
- Organizer
  第73回日本寄生虫学会西日本支部大会
- Data Source
  KAKENHI-PROJECT-15K15123
[Presentation] Development of See-Through Imaging Methods for Sexual Reproduction of Malaria Parasites.2017
- Author(s)
  Mori T, Hirai M, Mita T
- Organizer
  66th ASTMH
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03707
[Presentation] 原虫学・寄生虫学が現代のトップサイエンスにもたらす貢献マラリアミューテーター　マラリア原虫薬剤耐性進化解明の新たな研究ツール.2017
- Author(s)
  平井誠, 池田美恵, 橘真一郎, 美田敏宏.
- Organizer
  生命科学系学会合同年次大会.
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] ウガンダにおける熱帯熱マラリア原虫キニーネ感受性の実態.2017
- Author(s)
  山内祐人, 橘真一郎, 池田美恵, 関原誠, Balikagala B, 八代-櫻井美樹, 平井誠, Palacpac N, 木村英作, 堀井俊宏, 美田敏宏.
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] Detection of artemisinin-resistant Plasmodium falciparum isolates with ex-vivo ring-stage survival assay in Uganda.2017
- Author(s)
  Mita T, Ikeda M, Kaneko M, Balikagala B, Tachibana S-I, Sakurai-Yatsushiro M, Yatsushiro S, Takahashi N, Hashimoto M, Katuro O, Olia A, Obwoya P, Auma M, Anywar D, Odongo-Aginya E, Hirai M, Palacpac N, Kataoka M, Tsuboi T, Kimura E, Horii T.
- Organizer
  Keystone Symposia Conference: Malaria:
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] 希少糖D-アロースによるハマダラカ体内でのマラリア原虫発育阻止効果の検討2017
- Author(s)
  新井明治, 平井誠, 田中健Q, 寺中正人, 徳田雅明
- Organizer
  グローバルヘルス合同大会2017
- Data Source
  KAKENHI-PROJECT-15K15123
[Presentation] Development of See-Through Imaging Methods for Sexual Reproduction of Malaria Parasites.2017
- Author(s)
  Mori T, Hirai M, Mita T
- Organizer
  American Society of Tropical Medicine and Hygiene 66th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] 希少糖D-アロースはハマダラカ体内でマラリア原虫の発育分化を抑制する2017
- Author(s)
  新井明治, 平井誠, 田中健Q, 寺中正人, 徳田雅明
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-15K15123
[Presentation] マラリア原虫有性生殖の透視観察法の開発2017
- Author(s)
  森稔幸, 平井誠, 美田敏宏
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] マラリア原虫有性生殖の透視観察法の開発2017
- Author(s)
  森稔幸、平井誠、美田敏宏
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H03707
[Presentation] Prerequisite Emergence of Background Mutations for kelch13-related Artemisinin-Resistant Plasmodium falciparum isolates2017
- Author(s)
  Tachibana S-I, Hirai M, Mori T, Mita T
- Organizer
  American Society of Tropical Medicine and Hygiene 66th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08765
[Presentation] 「マラリアミューテーター：マラリア原虫薬剤耐性進化解明の新たな研究ツール」シンポジウム「原虫学・寄生虫学が現代のトップサイエンスにもたらす貢献」2017
- Author(s)
  平井誠
- Organizer
  2017年生命科学系学会合同次年会
- Invited
- Data Source
  KAKENHI-PROJECT-15K08453
[Presentation] Isolation of piperaquine resistant rodent malaria parasite from mutator malaria Malaria: Chemotherapy and Drug Resistance - Molecular Biology2017
- Author(s)
  Makoto Hirai, Mie Ikeda, Shin-Ichiro Tachibana, Toshihiro Mita
- Organizer
  Americal Society of Tropical Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08453
[Presentation] 「マラリア原虫の薬剤耐性機構解明に向けた取り組み」2017
- Author(s)
  平井誠
- Organizer
  第27回感染研シンポジウム－薬剤耐性菌の現状と対策－
- Invited
- Data Source
  KAKENHI-PROJECT-15K08453
[Presentation] Pb102, A Novel Gene Essential for Female Fertility or Ookinete Maturation of Murine Malaria Parasite, Plasmodium Berghei.2017
- Author(s)
  Maeta A, Hirai M, Mori T, Mita T
- Organizer
  American Society of Tropical Medicine and Hygiene 66th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] ネズミマラリア原虫の有性生殖関連分子の機能解析.2017
- Author(s)
  前多晟壮, 森稔幸, 平井誠, 美田敏宏.
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-17H04074
[Presentation] D-Allose inhibits growth and differentiation of the rodent malaria parasite, Plasmodium berghei in the vector mosquito2016
- Author(s)
  Arai M, Hirai M, Tanaka TQ, Teranaka M, Tokuda M
- Organizer
  The 6th Symposium of International Society of Rare Sugars
- Place of Presentation
  香川県高松市
- Year and Date
  2016-11-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15123
[Presentation] マラリア原虫の受精と薬剤耐性：マラリア制圧のための作用点2016
- Author(s)
  平井　誠
- Organizer
  第1073回生物科学セミナー
- Place of Presentation
  東京大学理学部
- Year and Date
  2016-06-15
- Invited
- Data Source
  KAKENHI-PUBLICLY-26117706
[Presentation] 高頻度突然変異マラリア原虫を用いた薬剤耐性機構解明への挑戦2016
- Author(s)
  平井誠・池田恵美・橘真一郎・美田敏宏
- Organizer
  日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PUBLICLY-26117706
[Presentation] 高頻度突然変異マラリア原虫を用いた薬剤耐性機構解明への挑戦2016
- Author(s)
  平井誠・池田美恵・橘真一郎・美田敏宏
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-16K08765
[Presentation] 比較トランスクリプトームによるマラリア原虫受精関連因子の探索2014
- Author(s)
  平井誠、新井明治、安彦真文、本間一、岡本龍史、鈴江一友、今井孝、谷口委代、堀井俊宏、田邉和裄、久枝一
- Organizer
  日本寄生虫学会
- Place of Presentation
  愛媛県松山市
- Data Source
  KAKENHI-PROJECT-24590501
[Presentation] 高頻度突然変異発生マラリア原虫(マラリアミューテーター)のゲノムワイド変異解析と薬剤耐性研究への応用2012
- Author(s)
  本間一、平井誠、中村昇太、後藤直久, 彦坂健児、美田敏宏、安永照雄、堀井俊宏、古澤満、田邉和裄(10人中1, 2, 10番目)
- Organizer
  第81回日本寄生虫学会大会
- Place of Presentation
  西宮
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-23659211
[Presentation] 比較トランスクリプトームによるマラリア原虫受精因子の探索2012
- Author(s)
  平井誠、安彦真文、岡本龍司、本間一、鈴江一友、今井孝、堀井俊宏、田邉和裄、久枝一
- Organizer
  第１０回分子寄生虫・マラリアフォーラム、第７２回日本寄生虫学会東日本支部会合同大会
- Place of Presentation
  群馬大学医学部
- Data Source
  KAKENHI-PUBLICLY-24112705
[Presentation] マラリア原虫をやっつける～その驚異、生態、新たな対策2012
- Author(s)
  平井　誠
- Organizer
  第2回　WIAS Top Runners’ Lecture Collection of Science
- Place of Presentation
  早稲田大学高等研究所
- Invited
- Data Source
  KAKENHI-PUBLICLY-24112705
[Presentation] 超加速変異型ネズミマラリア原虫の創出とその順遺伝学への応用2012
- Author(s)
  平井誠、本間一、中村昇太、後藤直久、美田敏宏、鈴江和友、今井孝、松岡裕之、安永照雄、古澤満、堀井俊宏、久枝一、田邉和裄(13人中1, 2, 13番目)
- Organizer
  第81回日本寄生虫学会大会
- Place of Presentation
  西宮(兵庫県)
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-23659211
[Presentation] 超加速変異型ネズミマラリテ原虫の創出とその順遺伝学くの応用2012
- Author(s)
  平井誠、本間一、中村昇太、後藤直久、美田敏宏、鈴江和友、今井孝、松岡裕之、安永照雄、古澤滿、堀井俊宏、久枝一、田邊和桁
- Organizer
  第81回日本寄生虫学会大会
- Place of Presentation
  兵庫医科大学(兵庫県)
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-23659211
[Presentation] 高頻度突然変異発生マラリア原虫(マラリアミューテーター)のゲノムワイド変異解析と薬剤耐性研究への応用2012
- Author(s)
  本間一、平井誠、中村昇太、後藤直久、彦坂健児、美田敏宏、安永照雄、堀井俊宏、古澤滿、田邊和桁
- Organizer
  第81回日本寄生虫学会大会
- Place of Presentation
  兵庫医科大学(兵庫県)
- Year and Date
  2012-03-23
- Data Source
  KAKENHI-PROJECT-23659211
[Presentation] 比較トランスクリプトームによるマラリア原虫受精因子の探索2012
- Author(s)
  平井誠、安彦真文、岡本龍司、本間一、鈴江一友、今井孝、堀井俊宏、田邉和裄、久枝一
- Organizer
  第１０回分子寄生虫・マラリアフォーラム、第７２回日本寄生虫学会東日本支部会合同大会
- Place of Presentation
  群馬大学医学部
- Data Source
  KAKENHI-PROJECT-24590501
[Presentation] 超加速変異(進化)型ネズミマラリア原虫の創出とその順遺伝学への応用2012
- Author(s)
  平井誠
- Organizer
  第81回日本寄生虫学会大会
- Place of Presentation
  兵庫医科大学
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PUBLICLY-22112519
[Presentation] マラリア原虫をやっつける～その驚異、生態、新たな対策2012
- Author(s)
  平井　誠
- Organizer
  第2回　WIAS Top Runners’ Lecture Collection of Science
- Place of Presentation
  早稲田大学
- Invited
- Data Source
  KAKENHI-PROJECT-24590501
[Presentation] Male fertility of malaria parasite is determined by GCS1, a plant-type reproduction factor2011
- Author(s)
  平井誠
- Organizer
  Malaria Mini-symposium
- Place of Presentation
  長崎大学熱帯医学研究所
- Year and Date
  2011-09-06
- Data Source
  KAKENHI-PUBLICLY-22112519
[Presentation] Male fertility of malaria parasite is determined by GCS1, a plant-type reproduction factor. Biology of Malaria2011
- Author(s)
  平井誠
- Organizer
  IUMS 2011
- Place of Presentation
  北海道札幌市
- Year and Date
  2011-09-08
- Data Source
  KAKENHI-PUBLICLY-22112519
[Presentation] GCS1を基軸としたマラリア原虫配偶子認識・膜融合機構の解明2011
- Author(s)
  平井誠
- Organizer
  第75回日本植物学会シンポジウム
- Place of Presentation
  東大駒場キャンパス
- Year and Date
  2011-09-18
- Data Source
  KAKENHI-PUBLICLY-22112519
[Presentation] Fertilization of malaria parasite is determined by GCS1, a definitive fertilization factor.2010
- Author(s)
  平井誠
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PUBLICLY-22112519
[Presentation] Fertilization of malaria parasite is determined by GCS1, a definitive fertilization factor.2010
- Author(s)
  平井誠
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20590426
[Presentation] Fertilization of malaria parasite is determined by GCS1, a definitive fertilization factor.2010
- Author(s)
  平井誠
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PUBLICLY-21022044
[Presentation] Fertilization of malaria parasite is determined by GCS1, a definitive fertilization factor.2010
- Author(s)
  平井誠
- Organizer
  第33回日本分子生物学会年会、「動植物に共通すアロ認証中核原理を探る」ワークショップ
- Place of Presentation
  神戸ポートピアホテル(兵庫県)
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-20590426
[Presentation] 北潔マラリア原虫コハク酸-ユビキノン還元酵素(複合体 II)の遺伝子破壊による表現型解析2009
- Author(s)
  日野明紀菜、平井誠、田中健、松岡裕之
- Organizer
  第78回日本寄生虫学会
- Place of Presentation
  法政大学(東京都)
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-20590426
[Presentation] Malaria parasites reproduce by similar manner to flowering plant2009
- Author(s)
  平井誠
- Organizer
  第9回あわじしま感染症・免疫フォーラム
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2009-09-08
- Data Source
  KAKENHI-PROJECT-20590426
[Presentation] Malaria parasites reproduce by similar manner to flowering plant.2009
- Author(s)
  平井誠
- Organizer
  第9回あわじしま感染症・免疫フォーラム
- Place of Presentation
  淡路夢舞台国際会議場(兵庫県)
- Year and Date
  2009-09-08
- Data Source
  KAKENHI-PROJECT-20590426
[Presentation] Malaria parasites reproduce by similar manner to flowering plant2009
- Author(s)
  平井誠
- Organizer
  第9回あわじしま感染症・免疫フォーラム
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2009-09-08
- Data Source
  KAKENHI-PUBLICLY-21022044
[Presentation] Mechanisms of malaria fertilization are highly conserved in various organisms.2008
- Author(s)
  平井誠
- Organizer
  JSPS presnts Sweden-Japan joint Seminar
- Place of Presentation
  カロリンスカ研究所(スウェーデン王国)
- Year and Date
  2008-06-11
- Data Source
  KAKENHI-PROJECT-20590426
[Presentation] アジア・アフリカにおけるG6PD変異症および日本国内におけるG6PD変異症の状況について2008
- Author(s)
  松岡裕之, 平井誠, Amadu Jalloh
- Organizer
  第7回分子寄生虫・マラリア研究フォーラム
- Place of Presentation
  愛媛県松山市
- Data Source
  KAKENHI-PROJECT-20406023
[Presentation] Introduction of rapid methods for malaria diagnosis and glucose-6-phosphate dehydrogenase activity test in malaria endemic areas in Asian and African countries.2008
- Author(s)
  Matsuoka H, Jalloh A, Hirai M, Kawamoto F
- Organizer
  XVIIth International Congress for TropicalMedicine and Malaria
- Place of Presentation
  韓国済州島
- Data Source
  KAKENHI-PROJECT-20406023
[Presentation] Introduction of rapid methods for malaria diagnosis and glucose-6-phosphate dehydrogenase activity test in malaria endemic areas in Asian and African countries.2008
- Author(s)
  Matsuoka H, Jalloh A, Hirai M, Kawamoto F
- Organizer
  XVIIth International Congress for Tropical Medicine and Malaria.(Abstract p422)
- Place of Presentation
  Korea
- Data Source
  KAKENHI-PROJECT-20406023
[Presentation] アジア・アフリカにおけるG6PD変異症および日本国内におけるG6PD変異症の状況について2008
- Author(s)
  松岡裕之, 平井誠, Amadu Jalloh
- Organizer
  第7回分子寄生虫・マラリア研究フォーラム(抄録集p20)
- Place of Presentation
  松山市
- Data Source
  KAKENHI-PROJECT-20406023
[Presentation] マラリア原虫オオシストスポロゾイト形成に必要なプロテアーゼ2008
- Author(s)
  平井誠、川合覚、新井明治、松岡裕之
- Organizer
  第77回日本寄生虫学会
- Place of Presentation
  長崎新聞文化ホール(長崎県)
- Year and Date
  2008-04-02
- Data Source
  KAKENHI-PROJECT-20590426
[Presentation] 東南アジア各国における熱帯熱マラリアの流行とglucose-6-phosphate dehydrogenase(G6PD)変異の.多様性について2006
- Author(s)
  松岡裕之, 新井明治, 平井誠
- Organizer
  第47回日本熱帯医学会大会
- Place of Presentation
  長崎市
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17406025

1. MATSUOKA Hiroyuki (10173816)

# of Collaborated Projects: 7 results

# of Collaborated Products: 19 results
2. ARAI Meiji (30294432)

# of Collaborated Projects: 7 results

# of Collaborated Products: 16 results
3. MITA Toshihiro (80318013)

# of Collaborated Projects: 5 results

# of Collaborated Products: 35 results
4. YOSHIDA Shigeto (10296121)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
5. KAWAMOTO Fumihiko (40115556)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
6. 大橋順 (80301141)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. MATSUDA Hajime (30114648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TANABE Kazuyuki (40047410)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. HONMA Hajime (10617468)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. HORII Toshihiro (80142305)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
11. NAKAMURA Shota (90432434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. TOKUDA Masaaki (10163974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
13. TERANAKA Masato (20294770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
14. Tachibana Shin-Ichiro (90414630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
15. Mori Toshiyuki (00462739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
16. 佐野元市郎 (30383730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 福田直到 (10913048)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Imai Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 近藤秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 久枝一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. 濱野真二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 橋本宗明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIRAI Makoto 平井 誠

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Organelle Genome Editing Unveils Drug Resistance Mechanisms in Malaria ParasitesPrincipal Investigator

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マラリア原虫がアルテミシニンに高度耐性化する遺伝的要因を予測する研究Principal Investigator

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Clarification of host adaptation mechanisms by using mutator malaria parasitePrincipal Investigator

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Method for mutation in organelle genome by CRISPR/CAS9Principal Investigator

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超加速進化型オルガネラゲノムを持つマラリア原虫の創成と予測進化学への応用Principal Investigator

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マラリア原虫ＧＣＳ１を基盤とした受精メカニズムの解明Principal Investigator

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Generation of rodent malaria parasite with high mutation rate and confirmation of its usefulness for next generation of malariologyPrincipal Investigator

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HIRAI Makoto 平井誠