Kashimoto Takashige 柏本孝茂

… Alternative Names

柏本孝茂カシモトタカシゲ

KASHIMOTO Takashigie 柏本孝茂

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Researcher Number	50327459
Other IDs	https://orcid.org/0000-0002-0888-909X
Affiliation (Current)	2025: 北里大学, 獣医学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2021: 北里大学, 獣医学部, 准教授 2014 – 2016: 北里大学, 獣医学部, 准教授 2004 – 2005: 北里大学, 獣医畜産学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related / Veterinary medical science / Bacteriology (including Mycology)
Keywords	Principal Investigator 敗血症 / バルニフィカス / 人食いバクテリア / 好中球 / ビブリオ / 人喰いバクテリア / 網羅的同定 / 好中球逃避機構 / 新規病原遺伝子同定法 / 感染モデル … More / リン脂質 / 新規治療法 / 生体内増殖 / 必須遺伝子 / 日和見感染 / 軟部組織壊死 / 病原性 / トランスポゾン / vulnificus / Vibrio / 増殖機構 / 壊死 / 免疫逃避 / 創傷感染 / LPS / 毒素 / イオンチャネル / アポトーシス / リンパ球減少 / 白血球減少 Less

Research Projects
(3 results)
Research Products
(20 results)

Analysis of evasion mechanisms of neutrophil killing by V. vulnificus.Principal Investigator
- Principal Investigator
  
  Kashimoto Takashige
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Kitasato University
Comprehensive identification of virlence genes of Vibrio vulnificusPrincipal Investigator
- Principal Investigator
  
  KASHIMOTO Takashigie
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Kitasato University
ビブリオ・バルニフィカス感染時に認められる白血球減少機構の解明Principal Investigator
- Principal Investigator
  
  柏本孝茂
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Kitasato University

All 2022 2020 2019 2018 2017 2016 2015 2005 Other

All Journal Article Presentation

[Journal Article] Increased Vascular Permeability Due to Spread and Invasion of Vibrio vulnificus in the Wound Infection Exacerbates Potentially Fatal Necrotizing Disease2022
- Author(s)
  Yamazaki Kohei、Kashimoto Takashige、Kado Takehiro、Yoshioka Kazuki、Ueno Shunji
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 13 Pages: 00-00
- DOI
  10.3389/fmicb.2022.849600
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02350
[Journal Article] Vibiro vulnificus hemolysin associates with gangliosides.2020
- Author(s)
  Kashimoto T, Sugiyama H, Kawamidori K, Yamazaki K, Kado T, Matsuda K, Kodama T, Mukai T, Ueno S.
- Journal Title
  
  BMC microbiology
  
  Volume: 30 Issue: 1 Pages: 1-9
- DOI
  10.1186/s12866-020-01755-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02350, KAKENHI-PROJECT-17K08829
[Journal Article] Chemotactic invasion in deep soft tissue by Vibrio vulnificus is essential for the progression of necrotic lesions2020
- Author(s)
  Yamazaki Kohei、Kashimoto Takashige、Kado Takehiro、Akeda Yukihiro、Yoshioka Kazuki、Kodama Toshio、Yamamoto Mai、Okamura Masashi、Kakuda Tsutomu、Ueno Shunji
- Journal Title
  
  Virulence
  
  Volume: 11 Issue: 1 Pages: 839-847
- DOI
  10.1080/21505594.2020.1782707
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02350
[Journal Article] Accurate prediction of anti‐phagocytic activity of Vibrio vulnificus by measurement of bacterial adherence to hydrocarbons. Prediction of Anti‐Phagocytic Activity2019
- Author(s)
  Takehiro Kado, Takashige Kashimoto*, Kohei Yamazaki, Kaho Matsuda, and Shunji Ueno
- Journal Title
  
  APMIS.
  
  Volume: 127 Issue: 2 Pages: 80-86
- DOI
  10.1111/apm.12910
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02350
[Journal Article] Identification of in vivo Essential Genes of Vibrio vulnificus for Establishment of Wound Infection by Signature-Tagged Mutagenesis2019
- Author(s)
  Kohei Yamazaki, Takashige Kashimoto*, Mio Morita, Takehiro Kado, Kaho Matsuda, Moeko Yamasaki, and Shunji Ueno
- Journal Title
  
  Front Microbiol.
  
  Volume: 10 Pages: 1-12
- DOI
  10.3389/fmicb.2019.00123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02350
[Journal Article] Importance of fumarate and nitrate reduction regulatory protein for intestinal proliferation of Vibrio vulnificus.2017
- Author(s)
  Kado T, Kashimoto T, Yamazaki K, Ueno S.
- Journal Title
  
  FEMS Microbiol Lett.
  
  Volume: 364 Issue: 1 Pages: fnw274-fnw274
- DOI
  10.1093/femsle/fnw274
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26450411
[Journal Article] Signature-tagged mutagenesis of Vibrio vulnificus2015
- Author(s)
  Mai YAMAMOTO, Takashige KASHIMOTO, Ping TONG, Jianbo XIAO, Michiko SUGIYAMA, Miyuki INOUE, Rie MATSUNAGA, Kohei HOSOHARA, Kazue NAKATA, Kenji YOKOTA, Keiji OGUMA, Koichiro YAMAMOTO
- Journal Title
  
  J Vet Med Sci.
  
  Volume: 未定
- NAID
  130005089947
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26450411
[Journal Article] Vibrio vulnificus detected in the spleen leads to fatal outcome in a mouse oral infection model.2015
- Author(s)
  Takashige Kashimoto , Chiemi Iwasaki , Masanori Gojo , Hiroyuki Sugiyama , Kazuki Yoshioka , Yuji Yamamoto , Masashi Okamura , Nobuyuki Susa , Shunji Ueno
- Journal Title
  
  FEMS Microbiol Lett.
  
  Volume: 362 Issue: 7
- DOI
  10.1093/femsle/fnv005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26450411
[Journal Article] Depletion of lymphocytes, but not neutrophils, via apoptosis in a murine model of Vibrio vulnificus infection.2005
- Author(s)
  Takashige Kashimoto
- Journal Title
  
  Journal of Medical Microbiology 54・1
  
  Pages: 15-22
- Data Source
  KAKENHI-PROJECT-16790259
[Presentation] 壊死筋肉組織はNSTI起因菌の生体内リザーバーとなる2019
- Author(s)
  柏本　孝茂、山﨑　浩平、上野　俊治
- Organizer
  令和元年度獣医学術東北地区学会
- Data Source
  KAKENHI-PROJECT-18H02350
[Presentation] Accurate prediction of anti‐phagocytic activity of Vibrio vulnificus by measurement of bacterial adherence to hydrocarbons.2019
- Author(s)
  Takashige Kashimoto, Takehiro Kado, Kohei Yamazaki, and Shunji Ueno
- Organizer
  8th Congress of European Microbiologists
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02350
[Presentation] 軟部組織壊死感染症における壊死性筋膜炎発症の意義2019
- Author(s)
  柏本　孝茂、山﨑　浩平、門　武宏、松田　果穂、上野　俊治
- Organizer
  第32回北里大学バイオサイエンスフォーラム
- Data Source
  KAKENHI-PROJECT-18H02350
[Presentation] Vibrio vulnificusの生体内における増殖・拡散に必須な因子の探索2019
- Author(s)
  大谷豪、柏本孝茂、山崎浩平、松田果穂、上野俊治
- Organizer
  第162回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02350
[Presentation] 壊死性軟部組織感染症において壊死した軟部組織は感染菌の生体内リザーバーとして機能する2019
- Author(s)
  Takashige KASHIMOTO, Kohei YAMAZAKI, Shunji UENO.
- Organizer
  日本細菌学会第93回総会
- Data Source
  KAKENHI-PROJECT-18H02350
[Presentation] Knock out of a putative transporter system in Vibrio vulnificus reduces lethality of mice.2018
- Author(s)
  Takehiro Kado, Takashige Kashimoto, Kohei Yamazaki, Yukihiro Akeda, Toshio Kodama, and Shunji Ueno
- Organizer
  The 17th Awaji International Forum on Infection and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02350
[Presentation] Chemotactic motility of V.vulnificus is required for lethality in mice2016
- Author(s)
  K. Yamazaki, T. Kashimoto, T, Kado, S. Ueno
- Organizer
  ASM microbe 2016
- Place of Presentation
  米国ボストン
- Year and Date
  2016-06-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450411
[Presentation] Mechanisms of V. vulnifcius wound infection. How does an opportunistic pathogen cause disease in healthy individuals?2016
- Author(s)
  Kashimoto T.
- Organizer
  Federation of Korean Microbiological Societies　2016
- Place of Presentation
  韓国ソウル
- Year and Date
  2016-11-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450411
[Presentation] Vibrio vulnificusの生体内生存因子の網羅的同定法の確立2015
- Author(s)
  柏本孝茂、山崎浩平、大沼孝詞、上野俊治
- Organizer
  獣医学術東北地区大会
- Place of Presentation
  ホテル東日本（岩手県盛岡市）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26450411
[Presentation] 鞭毛の回転方向は感染局所での菌の拡散と増殖に影響する2015
- Author(s)
  山﨑浩平、柏本孝茂、門武宏、後藤彩花、吉岡一機、上野俊治
- Organizer
  第158回日本獣医学会学術集会
- Place of Presentation
  北里大学獣医学部（青森県十和田市）
- Year and Date
  2015-09-07
- Data Source
  KAKENHI-PROJECT-26450411
[Presentation] Vibrio vulnificusの致死性に走化性制御因子cheYが及ぼす影響
- Author(s)
  山﨑浩平、柏本孝茂、門　武宏、後藤彩花、吉岡　一機、上野俊治
- Organizer
  第157回　日本獣医学会学術集会
- Place of Presentation
  北海道大学
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-26450411

Kashimoto Takashige 柏本 孝茂

柏本 孝茂 カシモト タカシゲ

KASHIMOTO Takashigie 柏本 孝茂

Research Projects

Research Products

Analysis of evasion mechanisms of neutrophil killing by V. vulnificus.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive identification of virlence genes of Vibrio vulnificusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ビブリオ・バルニフィカス感染時に認められる白血球減少機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Increased Vascular Permeability Due to Spread and Invasion of Vibrio vulnificus in the Wound Infection Exacerbates Potentially Fatal Necrotizing Disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vibiro vulnificus hemolysin associates with gangliosides.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemotactic invasion in deep soft tissue by Vibrio vulnificus is essential for the progression of necrotic lesions2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Accurate prediction of anti‐phagocytic activity of Vibrio vulnificus by measurement of bacterial adherence to hydrocarbons. Prediction of Anti‐Phagocytic Activity2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of in vivo Essential Genes of Vibrio vulnificus for Establishment of Wound Infection by Signature-Tagged Mutagenesis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Importance of fumarate and nitrate reduction regulatory protein for intestinal proliferation of Vibrio vulnificus.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Signature-tagged mutagenesis of Vibrio vulnificus2015

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Vibrio vulnificus detected in the spleen leads to fatal outcome in a mouse oral infection model.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Depletion of lymphocytes, but not neutrophils, via apoptosis in a murine model of Vibrio vulnificus infection.2005

Author(s)

Journal Title

Data Source

[Presentation] 壊死筋肉組織はNSTI起因菌の生体内リザーバーとなる2019

Author(s)

Organizer

Data Source

[Presentation] Accurate prediction of anti‐phagocytic activity of Vibrio vulnificus by measurement of bacterial adherence to hydrocarbons.2019

Author(s)

Organizer

Data Source

[Presentation] 軟部組織壊死感染症における壊死性筋膜炎発症の意義2019

Author(s)

Organizer

Data Source

[Presentation] Vibrio vulnificusの生体内における増殖・拡散に必須な因子の探索2019

Kashimoto Takashige 柏本孝茂

柏本孝茂カシモトタカシゲ

KASHIMOTO Takashigie 柏本孝茂