Tsujioka Takayuki 辻岡貴之

… Alternative Names

TSUJIOKA Takayuki 辻岡貴之

Less

Researcher Number	50330551
Other IDs
Affiliation (Current)	2025: 川崎医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 川崎医科大学, 医学部, 准教授 2021 – 2023: 川崎医科大学, 医学部, 准教授 2019: 川崎医科大学, 医学部, 准教授 2016 – 2018: 川崎医科大学, 医学部, 講師 2013: 川崎医科大学, 医学部, 講師 2009 – 2010: Kawasaki Medical School, 医学部, 講師 2008: 川崎医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Laboratory medicine / Basic Section 52010:General internal medicine-related Except Principal Investigator Laboratory medicine / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator CH25H / 25-オキシステロール / コレステロール-25-ハイドロキシラーゼ / DNAメチル化 / 白血病 / DNMTIs / MDS / 臨床検査医学 / ２５－OHC / 25-OHC … More / 増殖・分化 / 急性白血病 / G-CSFレセプター / 分化 / 好中球 / Syk … More Except Principal Investigator 抗体 / CD38 / 白血病移行 / 造血障害 / 腫瘍関連遺伝子 / 網羅的遺伝子解析 / 好中球機能 / 食細胞機能 / 血球異形成 / 遺伝子ノックダウン法 / 細胞分化 / プロテオーム / マイクロアレイ / 遺伝子 / 血液学 Less

Development of a new treatment strategy for hematological tumors targeting CD38 with reverse topology
- Principal Investigator
  
  北中明
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kawasaki Medical School
Stratification of patients with MDS for epigenetic agent from the viewpoint of cholesterol metabolic enzymePrincipal Investigator
- Principal Investigator
  
  Tsujioka Takayuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Kawasaki Medical School
Approach to mechanism of pathogenesis in MDS using DNA methylation analysisPrincipal Investigator
- Principal Investigator
  
  Tsujioka Takayuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kawasaki Medical School
Search for the molecules involved in leukemic transformation of myelodysplastic syndromes
- Principal Investigator
  
  TOHYAMA KAORU
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kawasaki Medical School
Approach to the molecular mechanisms of hematopoietic dysplasia aiming at elucidation of the pathogenesis of myelodysplastic syndromes
- Principal Investigator
  
  TOHYAMA Kaoru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kawasaki Medical School
The analysis of differentiative pathway in neutrophils using in vitro model and the pathogenic mechanisms of progression to leukemiaPrincipal Investigator
- Principal Investigator
  
  TSUJIOKA Takayuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kawasaki Medical School
Elucidation of the molecular mechanism leading to the dysplasia of blood cells in the myelodysplastic syndromes
- Principal Investigator
  
  TOHYAMA Kaoru
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Kawasaki Medical School

All 2016 2015 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] 病理形態学キーワード2010
- Author(s)
  辻岡貴之
- Total Pages
  2
- Publisher
  分光堂
- Data Source
  KAKENHI-PROJECT-21790546
[Book] 病理形態学キーワード2010
- Author(s)
  辻岡貴之, 他
- Publisher
  分光堂
- Data Source
  KAKENHI-PROJECT-21790546
[Book] 検査と技術2009
- Author(s)
  辻岡貴之
- Total Pages
  4
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21790546
[Book] 検査と技術2009
- Author(s)
  辻岡貴之, 他
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21790546
[Journal Article] Withaferin A suppresses the growth of myelodysplasia and leukemia cell lines by inhibiting cell cycle progression.2016
- Author(s)
  Okamoto S, Tsujioka T, Suemori SI, Kida JI, Kondo T, Tohyama Y, Tohyama K
- Journal Title
  
  Cancer Sci
  
  Volume: 107 Issue: 9 Pages: 1302-1314
- DOI
  10.1111/cas.12988
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460405, KAKENHI-PROJECT-26460691
[Journal Article] Five-aza-2'-deoxycytidine-induced hypomethylation of cholesterol 25-hydroxylase gene is responsible for cell death of myelodysplasia/leukemia cells.2015
- Author(s)
  Tsujioka T, Yokoi A, Itano Y, Takahashi K, Ouchida M, Okamoto S, Kondo T, Suemori S, Tohyama Y, Tohyama K
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 16709-16709
- DOI
  10.1038/srep16709
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460405, KAKENHI-PROJECT-26460691
[Journal Article] Rigosertib induces cell death of an MDS-derived cell line by DNA damage-induced G2/M arrest.2015
- Author(s)
  Hyoda T, Tsujioka T, Tohyama K, et al.
- Journal Title
  
  Cancer Science
  
  Volume: 106 Issue: 3 Pages: 287-293
- DOI
  10.1111/cas.12605
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460691
[Journal Article] Effects of DNA methyltransferase inhibitors (DNMTIs) on MDS-deribed cell lines.2013
- Author(s)
  Tsujioka T, Yokoi A, Kishimoto M, Kuyama A, Suemori S, Tohyama Y, Tohyama K
- Journal Title
  
  Exp Hematol
  
  Volume: 41 Issue: 2 Pages: 189-197
- DOI
  10.1016/j.exphem.2012.10.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590374, KAKENHI-PROJECT-23590696
[Journal Article] Rab27b regulates c-kit expression by controlling the secretion of stem cell factor.2012
- Author(s)
  Tanaka C
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 419 Issue: 2 Pages: 368-373
- DOI
  10.1016/j.bbrc.2012.02.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591127, KAKENHI-PROJECT-23590374, KAKENHI-PROJECT-23590696
[Journal Article] Approach to new therapeutics : Investigation by the use of MDS-derived cell lines2012
- Author(s)
  Tsujioka T, Matsuoka A, Tohyama Y, Tohyama K
- Journal Title
  
  Curr Pharm Design
  
  Volume: 18 Pages: 3204-3214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Approach to new therapeutics: Investigation by the use of MDS-derived cell lines.2012
- Author(s)
  Takayuki Tsujioka
- Journal Title
  
  Curr Pharm Design
  
  Volume: 18 Pages: 3204-3214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] 骨髄増殖性腫瘍におけるJAK2-V617F変異遺伝子比率と好中球アルカリホスファターゼスコアとの関連2011
- Author(s)
  奥野菜々子, 近藤敏範, 岸本光代, 辻岡貴之, 末盛晋一郎, 松岡亮仁, 久山亜紀, 田坂大象, 大倉貢, 野田幸代, 通山薫
- Journal Title
  
  日本検査血液学会雑誌
  
  Volume: 12 Pages: 170-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590696
[Journal Article] Application of laser scanning cytometry to clinical and laboratory hematology. (Pogorelov A eds.)2011
- Author(s)
  Tsujioka T, Tohyama K
- Journal Title
  
  Laser scanning, Theory and applications : INTECH, Vienna, Austria(依頼総説)
  
  Pages: 185-194
- Data Source
  KAKENHI-PROJECT-21790546
[Journal Article] 血液細胞における核膜蛋白lamin A/Cの発現とその局在2010
- Author(s)
  山本博美, 中原貴子, 久山亜紀 ,松岡亮仁, 辻岡貴之, 近藤敏範, 田坂大象, 通山薫
- Journal Title
  
  日本検査血液学会雑誌 11(2)
  
  Pages: 177-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790546
[Journal Article] フェリチン,血清鉄と鉄結合能2010
- Author(s)
  辻岡貴之
- Journal Title
  
  medicina
  
  Volume: 47 Pages: 281-284
- Data Source
  KAKENHI-PROJECT-21790546
[Journal Article] Lenalidomide induces cell death in an MDS-derived cell line with deletion of chromosome 5q by inhibition of cytokinesis.2010
- Author(s)
  Matsuoka A, Tochigi A, Kishimoto M, Nakahara T, Kondo T, Tsujioka T, Tasaka T, Tohyama Y, Tohyama K
- Journal Title
  
  Leukemia 24
  
  Pages: 748-755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790546
[Journal Article] Lenalidomide induces cell death in an MDS-derived cell line with deletion of chromosome 5q by inhibition of cytokinesis.2010
- Author(s)
  Matsuoka A, Tochigi A, Kishimoto M, Nakahara T, Kondo T, Tsujioka T, Tasaka T, Tohyama Y, Tohyama K
- Journal Title
  
  Leukemia 24
  
  Pages: 748-755
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590591
[Journal Article] 骨髄異形成症候群(MDS)のWHO分類20082010
- Author(s)
  辻岡貴之
- Journal Title
  
  Medical Technology
  
  Volume: 38 Pages: 443-444
- Data Source
  KAKENHI-PROJECT-21790546
[Journal Article] 造血器腫瘍における新WHO分類-骨髄系を中心に--2010
- Author(s)
  辻岡貴之
- Journal Title
  
  SRL宝函
  
  Volume: 31 Pages: 14-22
- Data Source
  KAKENHI-PROJECT-21790546
[Journal Article] 貧血の血液像2009
- Author(s)
  辻岡貴之
- Journal Title
  
  Medico 40(12)
  
  Pages: 475-478
- Data Source
  KAKENHI-PROJECT-21790546
[Journal Article] Impact of serum soluble interleukin-2 receptor levels on the diagnosis of malignant lymphoma.
- Author(s)
  Tsujioka T, Kisimoto M, Kondo T, Matsuoka A, Tasaka T, Sugihara T, Wada H, Tohyama K
- Journal Title
  
  Kawsaki Medical Journal in press
- NAID
  110008594177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790546
[Presentation] 骨髄異形成症候群の形態診断2010
- Author(s)
  辻岡貴之
- Organizer
  第57回日本臨床検査医学会2010シンポジウム12
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2010-09-12
- Data Source
  KAKENHI-PROJECT-21790546
[Presentation] Effect of a DNA methyltransferase inhibitor (decitabine) in an MDS-derived cell line.2010
- Author(s)
  Tsujioka T, Kishimot M, Matsuoka A, Kuyama A, Nakahara T, Mukae Y, Tasaka T, Tohyama K
- Organizer
  日本血液学会学術集会抄録集51(9)1112,2010
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21790546
[Presentation] 骨髄異形成症候群の形態診断2010
- Author(s)
  辻岡貴之, 通山薫
- Organizer
  日本臨床検査医学会学術集会抄録集58捕冊75, 2010
- Place of Presentation
  京王プラザホテル東京
- Year and Date
  2010-09-12
- Data Source
  KAKENHI-PROJECT-21790546
[Presentation] Effect of a DNA methyltransferase inhibitor (decitabine) in an MDS-derived cell line.2010
- Author(s)
  辻岡貴之
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21790546
[Presentation] 骨髄異形成症候群由来細胞株MDS-Lに対するlenalidomideの影響2008
- Author(s)
  松岡亮仁、近藤敏範、辻岡貴之、中原貴子、栃木亜紀、田坂大象、通山薫
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  国立京都国際会館(京都市)
- Year and Date
  2008-10-10
- Data Source
  KAKENHI-PROJECT-20590591

1. TOHYAMA Kaoru (80227561)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
2. TASAKA Taizo (80343309)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. SUEMORI Shin-ichiro (60330552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 北中明 (70343308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 今滝修 (60437697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 通山由美

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Tsujioka Takayuki 辻岡 貴之

TSUJIOKA Takayuki 辻岡 貴之

Research Projects

Research Products

Co-Researchers

Development of a new treatment strategy for hematological tumors targeting CD38 with reverse topology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Stratification of patients with MDS for epigenetic agent from the viewpoint of cholesterol metabolic enzymePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Approach to mechanism of pathogenesis in MDS using DNA methylation analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for the molecules involved in leukemic transformation of myelodysplastic syndromes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Approach to the molecular mechanisms of hematopoietic dysplasia aiming at elucidation of the pathogenesis of myelodysplastic syndromes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The analysis of differentiative pathway in neutrophils using in vitro model and the pathogenic mechanisms of progression to leukemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the molecular mechanism leading to the dysplasia of blood cells in the myelodysplastic syndromes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 病理形態学キーワード2010

Author(s)

Total Pages

Publisher

Data Source

[Book] 病理形態学キーワード2010

Author(s)

Publisher

Data Source

[Book] 検査と技術2009

Author(s)

Total Pages

Publisher

Data Source

[Book] 検査と技術2009

Author(s)

Publisher

Data Source

[Journal Article] Withaferin A suppresses the growth of myelodysplasia and leukemia cell lines by inhibiting cell cycle progression.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Five-aza-2'-deoxycytidine-induced hypomethylation of cholesterol 25-hydroxylase gene is responsible for cell death of myelodysplasia/leukemia cells.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rigosertib induces cell death of an MDS-derived cell line by DNA damage-induced G2/M arrest.2015

Author(s)

Journal Title

DOI

Data Source

Tsujioka Takayuki 辻岡貴之

TSUJIOKA Takayuki 辻岡貴之