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YAMAJI Toshiyuki  山地 俊之

ORCIDConnect your ORCID iD *help
Researcher Number 50332309
Other IDs
Affiliation (Current) 2022: 国立感染症研究所, 細胞化学部, 室長
Affiliation (based on the past Project Information) *help 2015 – 2021: 国立感染症研究所, 細胞化学部, 室長
2014: 国立感染症研究所, その他部局等, 主任研究官
2009 – 2014: National Institute of Infectious Diseases, 細胞化学部, 主任研究官
2008: National Institute of Infectious Diseases, 細胞化学部第二室, 研究員
Review Section/Research Field
Principal Investigator
Functional biochemistry / Basic Section 43030:Functional biochemistry-related
Except Principal Investigator
Environmental and hygienic pharmacy / Functional biochemistry / Basic Section 49060:Virology-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Keywords
Principal Investigator
スフィンゴ糖脂質 / 糖鎖 / ゲノムワイドスクリーニング / 志賀毒素 / 脂質 / 代謝 / スクリーニング / 糖脂質 / 遺伝子編集法 / 糖転移酵素 … More / トランスゴルジネットワーク / 細菌毒素 / TMBIMファミリー / FAIM2 / 膜タンパク / shRNA / ゲノム編集法 / ゴルジ体 / ゲノム編集 / 脂質輸送 / 膜輸送 / スフィンゴ脂質 / サルベージ経路 / リソソーム … More
Except Principal Investigator
ゲノム編集 / 脂質 / セラミド / 脂質輸送 / HeLa細胞 / クラミジア / 感染症 / Vero細胞 / 膜輸送 / 輸送タンパク質 / スフィンゴミエリン / リン酸化 / 小胞体 / ゴルジ体 / タンパク質リン酸化 / スフィンゴ脂質 / 生体膜 / 輸送 / プレクストリン相同ドメイン / ホスホイノシチド / 細胞内寄生 / ワクチン細胞基材 / ゲノム / 性感染症 / クラミジア菌 / プレスクトリン相同ドメイン / 細胞基材 / ベロ細胞 / 宿主細胞 / ウイルス / ワクチン / フラビウイルス / ウイルス感染症 / Huh細胞 / HPV / 細胞侵入 / CRISPR-Cas9 / sgRNAライブラリー / E2 / ヒトパピローマウイルス / 黄熱ウイルス / レプリコン / 宿主因子 / スクリーニング / 細胞改変 Less
  • Research Projects

    (10 results)
  • Research Products

    (130 results)
  • Co-Researchers

    (28 People)
  •  ゲノムワイド探索に基づくスフィンゴ脂質再利用経路の包括的な分子機構解明Principal Investigator

    • Principal Investigator
      山地 俊之
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      National Institute of Infectious Diseases
  •  A replicon-based screen of yellow fever virus host factors: Toward generation of highly productive virus-producer cell lines

    • Principal Investigator
      齊藤 恭子
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      National Institute of Infectious Diseases
  •  オミックス解析によるヒトパピローマウイルス細胞内侵入機構の解明

    • Principal Investigator
      石井 克幸
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      National Institute of Infectious Diseases
  •  CRISPRライブラリーを用いたグルコシルセラミドの脂質二重膜間輸送因子の探索Principal Investigator

    • Principal Investigator
      山地 俊之
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      National Institute of Infectious Diseases
  •  Genomics-based improvement of Vero cells for virus growth

    • Principal Investigator
      Hanada Kentaro
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental and hygienic pharmacy
    • Research Institution
      National Institute of Infectious Diseases
  •  Search for new factors involved in glycolipid metabolism and transport by a genome-wide shRNA screenPrincipal Investigator

    • Principal Investigator
      Yamaji Toshiyuki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional biochemistry
    • Research Institution
      National Institute of Infectious Diseases
  •  Molecular strategy for the prevention of Chlamydia hijacking of a host lipid transport system

    • Principal Investigator
      HANADA KENTARO
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental and hygienic pharmacy
    • Research Institution
      National Institute of Infectious Diseases
  •  Regulation of glycosphingolipids biosynthesis by multi-spanning transmembrane protein family TMBIMs and their molecular machineryPrincipal Investigator

    • Principal Investigator
      YAMAJI Toshiyuki
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      National Institute of Infectious Diseases
  •  Regulatory mechanism of intracellular trafficking of ceramide

    • Principal Investigator
      HANADA KENTARO
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      National Institute of Infectious Diseases
  •  A genetic biochemical search and analysis for factors involved in glycosphingolipid metabolism and trafficPrincipal Investigator

    • Principal Investigator
      YAMAJI Toshiyuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      National Institute of Infectious Diseases

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

  • [Journal Article] Poliovirus-nonsusceptible Vero cell line for the World Health Organization global action plan2021

    • Author(s)
      Okemoto-Nakamura Y, Someya K, Yamaji T, Saito K, Takeda M, Hanada K
    • Journal Title

      Sci Rep

      Volume: 11 Pages: 6746-6746

    • DOI

      10.1038/s41598-021-86050-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Journal Article] Galabiosylceramide is present in human cerebrospinal fluid2021

    • Author(s)
      Akiyama H, Ide M, Yamaji T, Mizutani Y, Niimi Y, Mutoh T, Kamiguchi H, Hirabayashi Y.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 536 Pages: 73-79

    • DOI

      10.1016/j.bbrc.2020.12.051

    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Journal Article] Golgi maturation-dependent glycoenzyme recycling controls glycosphingolipid biosynthesis and cell growth via GOLPH3.2021

    • Author(s)
      Rizzo R et al., (Yamaji T 22番目/31人)
    • Journal Title

      The EMBO Journal

      Volume: 40

    • DOI

      10.15252/embj.2020107238

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-20K06650, KAKENHI-PLANNED-17H06420, KAKENHI-PROJECT-18H05275
  • [Journal Article] Concise and Reliable Syntheses of Glycodendrimers via Self-Activating Click Chemistry: A Robust Strategy for Mimicking Multivalent Glycan-Pathogen Interactions2020

    • Author(s)
      Farabi K, Manabe Y, Ichikawa H, Miyake S, Tsutsui M, Kabayama K, Yamaji T, Tanaka K, Hung S-C, Fukase K.
    • Journal Title

      The Journal of Organic Chemistry

      Volume: 85 Pages: 16014-16023

    • DOI

      10.1021/acs.joc.0c01547

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-20K05727, KAKENHI-PLANNED-15H05836, KAKENHI-PROJECT-16H05924, KAKENHI-PUBLICLY-20H04709, KAKENHI-PROJECT-20H05675
  • [Journal Article] Identification of Characteristic Genomic Markers in Human Hepatoma HuH-7 and Huh7.5.1-8 Cell Lines2020

    • Author(s)
      Kawamoto M#, Yamaji T#, Saito K, Shirasago Y, Satomura K, Endo T, Fukasawa M, Hanada K, Osada N.
    • Journal Title

      Frontiers in Genetics

      Volume: 11 Pages: 546106-546106

    • DOI

      10.3389/fgene.2020.546106

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07357, KAKENHI-PLANNED-18H05511
  • [Journal Article] Blood group P1 antigen?bearing glycoproteins are functional but less efficient receptors of Shiga toxin than conventional glycolipid-based receptors2020

    • Author(s)
      Morimoto K, Suzuki N, Tanida I, Kakuta S, Furuta Y, Uchiyama Y, Hanada K, Suzuki Y, Yamaji T.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 295 Pages: 9490-9501

    • DOI

      10.1074/jbc.ra120.013926

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-20K06520, KAKENHI-PUBLICLY-20H05342
  • [Journal Article] Preparation of Fluorescent Recombinant Shiga Toxin B Subunit and Its Application to Flow Cytometry2020

    • Author(s)
      Yamaji T
    • Journal Title

      Methods Mol Biol,

      Volume: 2132 Pages: 463-474

    • DOI

      10.1007/978-1-0716-0430-4_45

    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Journal Article] Comparative characterization of flavivirus production in two cell lines: Human hepatoma-derived Huh7.5.1-8 and African green monkey kidney-derived Vero2020

    • Author(s)
      Kyoko Saito, Masayoshi Fukasawa, Yoshitaka Shirasago, Ryosuke Suzuki, Naoki Osada, Toshiyuki Yamaji, Takaji Wakita, Eiji Konishi, Kentaro Hanada
    • Journal Title

      PLOS ONE

      Volume: 15

    • DOI

      10.1371/journal.pone.0232274

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08362, KAKENHI-PROJECT-17K07357, KAKENHI-PLANNED-18H05511
  • [Journal Article] Sphingomyelin Is Essential for the Structure and Function of the Double-Membrane Vesicles in Hepatitis C Virus RNA Replication Factories2020

    • Author(s)
      Gewaid H, Aoyagi H, Arita M, Watashi K, Suzuki R, Sakai S, Kumagai K, Yamaji T, Fukasawa M, Kato F, Hishiki T, Mimata A, Sakamaki Y, Ichinose S, Hanada K, Muramatsu M, Wakita T, Aizaki H.
    • Journal Title

      Journal of Virology

      Volume: 94

    • DOI

      10.1128/jvi.01080-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-20K07532, KAKENHI-PROJECT-20K08369, KAKENHI-PROJECT-17K08870
  • [Journal Article] Chlamydia trachomatis-infected human cells convert ceramide to sphingomyelin without sphingomyelin synthases 1 and 22020

    • Author(s)
      Tachida Yuriko、Kumagai Keigo、Sakai Shota、Ando Shuji、Yamaji Toshiyuki、Hanada Kentaro
    • Journal Title

      FEBS Letters

      Volume: 594 Pages: 519-529

    • DOI

      10.1002/1873-3468.13632

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-18K06649, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06417
  • [Journal Article] A CRISPR screen identifies LAPTM4A and TM9SF proteins as glycolipid-regulating factors2019

    • Author(s)
      Yamaji T, Sekizuka T, Tachida Y, Sakuma C, Morimoto K, Kuroda M, Hanada K
    • Journal Title

      iScience

      Volume: 11 Pages: 409-424

    • DOI

      10.1016/j.isci.2018.12.039

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07357, KAKENHI-PLANNED-17H06417
  • [Journal Article] 哺乳動物のセラミド関連脂質生合成2019

    • Author(s)
      山地俊之
    • Journal Title

      セラミド研究の新展開~基礎から応用へ~

      Volume: 0 Pages: 22-31

    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Journal Article] A CRISPR Screen Using Subtilase Cytotoxin Identifies SLC39A9 as a Glycan-regulating Factor.2019

    • Author(s)
      Yamaji Toshiyuki、Hanamatsu Hisatoshi、Sekizuka Tsuyoshi、Kuroda Makoto、Iwasaki Norimasa、Ohnishi Makoto、Furukawa Jun-ichi、Yahiro Kinnosuke、Hanada Kentaro
    • Journal Title

      iScience

      Volume: 15 Pages: 407-420

    • DOI

      10.1016/j.isci.2019.05.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07357, KAKENHI-PROJECT-19K07534, KAKENHI-ORGANIZER-17H06413, KAKENHI-PLANNED-17H06417
  • [Journal Article] Nanotubes connecting B lymphocytes: High impact of differentiation-dependent lipid composition on their growth and mechanics2017

    • Author(s)
      Toth EA, Oszvald A, Peter M, Balogh G, Osteikoetxea- Molnar A, Bozo T, Szabo-Meleg E, Nyitrai M, Derenyi I, Yamaji T, Hanada K, Vigh L, Matko J
    • Journal Title

      Biochimica et Biophysica Acta

      Volume: 1862 Pages: 991-1000

    • DOI

      10.1016/j.bbalip.2017.06.011

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Journal Article] Role of Intracellular Lipid Logistics in the Preferential Usage of Very Long Chain-Ceramides in Glucosylceramide2016

    • Author(s)
      Yamaji T, Horie A, Tachida Y, Sakuma C, Suzuki Y, Kushi Y, Hanada K
    • Journal Title

      Int J Mol Sci

      Volume: 17

    • DOI

      10.3390/ijms17101761

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26440069
  • [Journal Article] Sphingolipid metabolism and interorganellar transport: localization of sphingolipid enzymes and lipid transfer proteins2015

    • Author(s)
      Toshiyuki Yamaji and Kentaro Hanada
    • Journal Title

      Traffic

      Volume: 16 Pages: 101-122

    • DOI

      10.1111/tra.12239

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460086, KAKENHI-PROJECT-25670065, KAKENHI-PROJECT-26440069
  • [Journal Article] Establishment of HeLa cell mutants deficient in sphingolipid- related genes using TALENs2014

    • Author(s)
      Yamaji T, Hanada K.
    • Journal Title

      PLoS One

      Volume: 9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Journal Article] Establishment of HeLa Cell Mutants Deficient in Sphingolipid-related Genes Using TALENs2014

    • Author(s)
      Yamaji T, and Hanada K
    • Journal Title

      PLoS One

      Volume: 9

    • DOI

      10.1371/journal.pone.0088124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22370054, KAKENHI-PROJECT-23770164, KAKENHI-PROJECT-25670065
  • [Journal Article] The genome landscape of the african green monkey kidney-derived vero cell line2014

    • Author(s)
      Osada N, Kohara A, Yamaji T, Hirayama N, Kasai F, Sekizuka T, Kuroda M, Hanada K
    • Journal Title

      DNA Research

      Volume: 21 Pages: 673-683

    • DOI

      10.1093/dnares/dsu029

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PLANNED-23113008, KAKENHI-PLANNED-23117005, KAKENHI-PROJECT-25670065, KAKENHI-PROJECT-26251040, KAKENHI-PROJECT-26440069
  • [Journal Article] Binding of a sialic acid-recognizing lectin Siglec-9 modulates adhesion dynamics of cancer cells via calpain-mediated protein degradation2013

    • Author(s)
      Sabit I, Hashimoto N, Matsumoto Y, Yamaji T, Furukawa K, Furukawa K.
    • Journal Title

      J Biol Chem

      Volume: 288 Pages: 35417-27

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Journal Article] Binding of a sialic acid-recognizing lectin Siglec-9 modulates adhesion dynamics of cancer cells via calpain-mediated protein degradation2013

    • Author(s)
      Sabit I.
    • Journal Title

      J. Biol. Chem.

      Volume: 288 Pages: 35417-27

    • DOI

      10.1074/jbc.m113.513192

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590371, KAKENHI-PROJECT-23770164, KAKENHI-PROJECT-24390078
  • [Journal Article] Genetic variation of human papillomavirus type 16 in individual clinical specimens revealed by deep sequencing2013

    • Author(s)
      Kukimoto I, Maehama T, Sekizuka T, Ogasawara Y, Kondo K, Kusumoto-Matsuo R, Mori S, Ishii Y, Takeuchi T, Yamaji T, Takeuchi F, Hanada K, Kuroda M.
    • Journal Title

      PLoS One

      Volume: 8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Journal Article] Colonic epithelial cells express specific ligands for mucosal macrophage immunosuppressive receptors, siglec-7 and -92012

    • Author(s)
      Miyazaki, K., Sakuma, K., Kawamura, Y. I., Izawa, M., Ohmori, K., Mitsuki, M., Yamaji, T., Hashimoto, Y., Suzuki, A., Saito, Y., Dohi, T., and Kannagi, R.
    • Journal Title

      Journal of Immunology

      Volume: 188 Pages: 4690-4700

    • DOI

      10.4049/jimmunol.1100605

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590324, KAKENHI-PROJECT-22590712, KAKENHI-PROJECT-22790774, KAKENHI-PUBLICLY-23112520, KAKENHI-PROJECT-23590955, KAKENHI-PROJECT-23770164
  • [Journal Article] Structural basis for the Golgi-association by the pleckstrin homology domain of the ceramide trafficking protein CERT2012

    • Author(s)
      Sugiki T, Takeuchi K, Yamaji T, Takano T, Tokunaga Y, Kumagai K, Hanada K, Takahashi H, and Shimada I
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 287 Pages: 33706-3371

    • DOI

      10.1074/jbc.m112.367730

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22370054, KAKENHI-PROJECT-23770164, KAKENHI-PROJECT-23790064, KAKENHI-PROJECT-23790118, KAKENHI-PROJECT-24370048, KAKENHI-PROJECT-24890263, KAKENHI-PUBLICLY-23107735, KAKENHI-PUBLICLY-24102524
  • [Journal Article] "3D Modeling of a Natural Killer Receptor, Siglec-7 : Critical Amino Acids for Glycan-Binding and Cell Death-Inducing Activity"「Modeling and Simulation in Engineering」2012

    • Author(s)
      Yamaji T., Yamaguchi Y., Mitsuki M., Takashima S., Waguri S., Hashimoto Y., Nara K.
    • Journal Title

      INTECH

      Volume: (ISBN : 978-953-307- 959-2, 103-116)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Journal Article] Structural basis for the Golgi association by the pleckstrin homology domain of the ceramide trafficking protein (CERT)2012

    • Author(s)
      Sugiki T, Takeuchi K, Yamaji T, Takano T, Tokunaga Y, Kumagai K, Hanada K, Takahashi H, Shimada I.
    • Journal Title

      J Biol Chem

      Volume: 287 Pages: 33706-18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Journal Article] Colonic epithelial cells express specific ligands for mucosal macrophage immunosuppressive receptors siglec-7 and -92012

    • Author(s)
      Miyazaki K, Sakuma K, Kawamura YI, Izawa M, Ohmori K, Mitsuki M, Yamaji T, Hashimoto Y, Suzuki A, Saito Y, Dohi T, Kannagi R.
    • Journal Title

      J Immunol

      Volume: 188 Pages: 4690-700

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Journal Article] 3D Modeling of a Natural Killer Receptor, Siglec-7: Critical Amino Acids for Glycan-Binding and Cell Death-Inducing Activity2011

    • Author(s)
      Yamaji T., Yamaguchi Y., Mitsuki M., Takashima S., Waguri S., Hashimoto Y., and Nara K.
    • Journal Title

      「Modeling and Simulation in Engineering, INTECH

      Volume: ISBN: 978-953-307-959-2 Pages: 103-116

    • DOI

      10.5772/31157

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Journal Article] Siglec-7 mediates nonapoptotic cell death independently of its immunoreceptor tyrosine-based inhibitory motifs in monocytic cell line U9372010

    • Author(s)
      Mitsuki, M., Nara, K., Yamaji, T., Enomoto, A., Kanno, M., Yamaguchi, Y., Yamada, A., Waguri, S., Hashimoto, Y.
    • Journal Title

      Glycobiology 20(3)

      Pages: 395-402

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Journal Article] Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturb a trans-Golgi network enzyme, Gb3 synthase, and reduce Gb3 biosynthesis.2010

    • Author(s)
      Yamaji, T., Nishikawa, K., Hanada, K.
    • Journal Title

      J.Biol.Chem. 285

      Pages: 35505-35518

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Journal Article] Siglec-7 mediates non-apoptotic cell death independently of its immunoreceptor tyrosine-based inhibitory motifs in monocytic cell line U937.2010

    • Author(s)
      Mitsuki, M., Nara, K., Yamaji, T., Enomoto A., Kanno, M., Yamaguchi, Y., Yamada, A., Waguri, S., Hashimoto, Y. (equal contribution)
    • Journal Title

      Glycobiology 20

      Pages: 395-402

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Journal Article] Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturb a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesis2010

    • Author(s)
      Yamaji T, Nishikawa K, and Hanada K
    • Journal Title

      J Biol Chem

      Volume: 285 Pages: 35505-35518

    • DOI

      10.1074/jbc.m110.154229

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Journal Article] Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturbs a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesis2010

    • Author(s)
      Toshiyuki Yamaji
    • Journal Title

      The Journal of Biological Chemistry

      Volume: 285 Pages: 35505-35518

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Journal Article] Transmembrane BAX inhibitor motif containing (TMBIM) family proteins perturbs a trans-Golgi network enzyme, Gb3 synthase, and reduces Gb3 biosynthesis2010

    • Author(s)
      Yamaji, T., Nishikawa, K., Hanada, K.
    • Journal Title

      Journal of Biological Chemistry

      Volume: 285 Pages: 35505-35518

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Journal Article] CERT-mediated trafficking of ceramide.2009

    • Author(s)
      Hanada, K., Kumagai, K., Tomishige, N., Yamaji, T.
    • Journal Title

      Biochim. Biophys.A cta 1791

      Pages: 684-691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Journal Article] CERT-mediated trafficking of ceramide2009

    • Author(s)
      Hanada, K., Kumagai, K., Tomishige, N., Yamaji, T.
    • Journal Title

      Biochim Biophys Acta. 1791(7)

      Pages: 684-691

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Journal Article] CERT-mediated trafficking of ceramide2009

    • Author(s)
      Hanada, K., Kumagai, K., Tomishige, N., and Yamaji, T.
    • Journal Title

      Biochim Biophys Acta. (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Journal Article] Two sphingolipid transfer proteins, CERT and FAPP2 : Their roles in sphingolipid metabolism.2008

    • Author(s)
      Yamaji, T., Kumagai, K., Tomishige, N., Hanada, K.
    • Journal Title

      IUBMB Life 60

      Pages: 511-518

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Journal Article] Two sphingolipid transfer proteins, CERT and FAPP2 : Their roles in sphingolimd metabolism2008

    • Author(s)
      Yamaji, T., Kumagai, K., Tomishige, N., and Hanada, K.
    • Journal Title

      IUBMB Life. 60(8)

      Pages: 511-518

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] ゲノム編集法を用いた生体膜脂質や糖鎖の代謝及び感染症研究2021

    • Author(s)
      山地俊之
    • Organizer
      東京医科歯科大学大学院特別セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] Application of genome editing technologies to studies on sphingolipid biology2021

    • Author(s)
      山地俊之
    • Organizer
      第141回日本薬学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] 8.Modulation of Zika virus replication via glucosylceramide 1 synthase and glycosphingolipids2021

    • Author(s)
      Brown M, Cerone J, Ogbamikael S, Yager E, Yamaji T, Barroso M, Hanada K, Konan K
    • Organizer
      Eastern Society for Pediatric Research Annual Meeting ESPR2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] P1糖鎖エピトープを有する糖タンパク質の志賀毒素受容体としての機能解析2020

    • Author(s)
      森本貫太、鈴木詔子、谷田以誠、角田宗一郎、古田陽子、内山安男、花田賢太郎、鈴木佑典、山地俊之
    • Organizer
      第39回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] ヒト脳脊髄液にはガラビオシルセラミド(Gb2)が存在する2020

    • Author(s)
      秋山央子、井出三津子、山地俊之、植田晃広、新美芳樹、武藤多津郎、上口裕之、平林義雄
    • Organizer
      第62回脂質生化学会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] 小胞体-ゴルジ体連携ゾーンにおけるCERTの機能制御に関する因子の探索2020

    • Author(s)
      水池彩、酒井祥太、山地俊之、花田賢太郎
    • Organizer
      第62回脂質生化学会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] スフィンゴ脂質のC型肝炎ウイルス複製における役割の解析2020

    • Author(s)
      相崎英樹、青柳東代、若江亨祥、有田峰太郎、渡士幸一、鈴木亮介、熊谷圭悟、山地俊之、深澤征義、村松正道、脇田隆字、花田賢太郎
    • Organizer
      第62回脂質生化学会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] ヒトマクロファージの免疫応答における極長鎖脂肪酸鎖を含むスフィンゴ脂質の役割2020

    • Author(s)
      花房慶、中山仁志、山地俊之、岩渕和久
    • Organizer
      第39回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] CRISPRライブラリーを用いたSubtilase cytotoxinによる致死に耐性を示す細胞の樹立と受容体認識機構の解明2019

    • Author(s)
      八尋錦之助、大西真、花田賢太郎、山地俊之
    • Organizer
      第23回腸管出血性大腸菌研究会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] 糖鎖結合性細菌毒素を用いたゲノムワイドCRISPRスクリーニング2019

    • Author(s)
      山地俊之
    • Organizer
      第93回日本細菌学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] P1糖鎖エピトープを有した糖タンパク質の志賀毒素受容体としての機能解析2019

    • Author(s)
      森本貫太、鈴木詔子、花田賢太郎、鈴木佑典、山地俊之
    • Organizer
      第92回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] Application of genome editing technologies to studies on sphingolipid and glycan metabolisms2019

    • Author(s)
      Toshiyuki Yamaji
    • Organizer
      1st Japan-Europe Workshop on Glycosphingolipids and Membrane homeostatsis
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] ゲノムワイドCRISPR/Cas9スクリーニングシステムのin silico解析webアプリケーション2019

    • Author(s)
      関塚剛史、佐久間智理、糸川健太郎、花田賢太郎、黒田誠、山地俊之
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] ゲノムワイドスクリーニングによって同定された糖鎖発現制御因子の解析2019

    • Author(s)
      山地俊之、 関塚剛史、花松久寿、黒田誠、古川潤一、八尋錦之助、花田賢太郎
    • Organizer
      第38回日本糖質学会年会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] Genome-wide CRISPR screens identify novel glycan regulators2019

    • Author(s)
      Toshiyuki Yamaji, Tsuyoshi Sekizuka, Hisatoshi Hanamatsu, Makoto Kuroda, Jun-ichi Furukawa, Kinnosuke Yahiro, Kentaro Hanada
    • Organizer
      25th International Symposium on Glycoconjugates
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] Chlamydia trachomatisは細胞内寄生に宿主のスフィンゴミエリン生合成を必要としない2018

    • Author(s)
      立田由里子, 熊谷圭悟, 酒井祥太, 山地俊之, 花田賢太郎
    • Organizer
      第60回日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] Genome-Wide CRISPR Screening for Identifying Genes Involved in Glycolipid Metabolism2018

    • Author(s)
      Yamaji T, Hanada K
    • Organizer
      Gordon Research Conference on Glycolipid and Sphingolipid Biology
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] 遺伝子編集法を用いた宿主細胞因子の探索及び糖鎖生合成研究への応用2018

    • Author(s)
      山地俊之
    • Organizer
      第16回糖鎖科学コンソーシアムシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] Chlamydia trachomatisは細胞内寄生に宿主のスフィンゴミエリン生合成を必要としない2018

    • Author(s)
      立田由里子, 熊谷圭悟, 酒井祥太, 山地俊之, 花田賢太郎
    • Organizer
      第11回セラミド研究会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] ゲノム編集法を用いた糖鎖・脂質代謝関連因子の探索2018

    • Author(s)
      山地俊之
    • Organizer
      第2回オルガネラゾーン研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] CRISPRライブラリーを用いた糖脂質生合成に影響を及ぼす因子の探索2017

    • Author(s)
      山地俊之、関塚剛史、佐久間智理、立田由里子、黒田誠、花田賢太郎
    • Organizer
      2017年度生命科学系学会合同年次大会 第40回日本分子生物学会年会・第90回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] CRISPRライブラリーを用いた志賀毒素の細胞障害作用に対するゲノムワイドスクリーニング2017

    • Author(s)
      山地俊之、立田由里子、佐久間智理、関塚剛史、黒田誠、花田賢太郎
    • Organizer
      第59回日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-17K07357
  • [Presentation] HaloTagテクノロジーを用いた細胞表面へのGb3糖鎖提示システムの構築と評価2016

    • Author(s)
      三宅秀斗,樺山一哉,真鍋良幸,Siyu Chen,山地俊之,花田賢太郎,深瀬浩一
    • Organizer
      日本化学会第96春季年会
    • Place of Presentation
      京田辺
    • Year and Date
      2016-03-24
    • Data Source
      KAKENHI-PROJECT-26440069
  • [Presentation] Application of genome editing technologies for studies on sphingolipid and glycan metabolisms2016

    • Author(s)
      Toshiyuki Yamaji, Tsuyoshi Sekizuka, Kinnosuke Yahiro, Yuriko Tachida, Chisato Sakuma, Makoto Kuroda, Kentaro Hanada
    • Organizer
      EMBO Workshop “Glycosylation in the Golgi complex”
    • Place of Presentation
      Vico Equense, Italy
    • Year and Date
      2016-10-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26440069
  • [Presentation] ゲノム編集技術を用いたスフィンゴ脂質・糖鎖の代謝研究2016

    • Author(s)
      山地 俊之、関塚 剛史、八尋 錦之助、鈴木 佑典、櫛 泰典、黒田 誠、花田賢太郎
    • Organizer
      第35回日本糖質学会年会
    • Place of Presentation
      高知
    • Year and Date
      2016-09-01
    • Data Source
      KAKENHI-PROJECT-26440069
  • [Presentation] Chlamydia hijacking of the host cell CERT2015

    • Author(s)
      Kentaro Hanada, Toshiyuki Yamaji, Keigo Kumagai
    • Organizer
      第10回スフィンゴテラピィ研究会
    • Place of Presentation
      金沢
    • Year and Date
      2015-06-16
    • Data Source
      KAKENHI-PROJECT-26440069
  • [Presentation] 慢性骨髄性白血病細胞株K562細胞の膜脂質組成によるγ-グロビン発現制御機構2015

    • Author(s)
      田村 恭祐、鈴木 佑典、山地 俊之、長谷川 拓馬、稲岡 夏希、野崎 真李果、櫛 泰典
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26440069
  • [Presentation] クラミジア・トラコマティスによってハイジャックされる宿主セラミド輸送機構2015

    • Author(s)
      熊谷 圭悟、山地 俊之、山本 章嗣、花田 賢太郎
    • Organizer
      第38回日本分子生物学会年会、第88回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26440069
  • [Presentation] 志賀毒素の細胞障害作用を指標としたゲノムワイドshRNAスクリーニング2015

    • Author(s)
      山地 俊之、堀江 亜矢、関塚 剛史、竹内 史比古、黒田 誠、花田 賢太郎
    • Organizer
      第57回脂質生化学会
    • Place of Presentation
      東京
    • Year and Date
      2015-05-28
    • Data Source
      KAKENHI-PROJECT-26440069
  • [Presentation] 志賀毒素の細胞傷害作用に対するゲノムワイドshRNAスクリーニング2014

    • Author(s)
      堀江亜矢、関塚剛史、竹内史比古、黒田誠、花田賢太郎、山地俊之
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-18
    • Data Source
      KAKENHI-PROJECT-26440069
  • [Presentation] TALEN-mediated disruption of several sphingolipid-related genes in a HeLa cell line2014

    • Author(s)
      Yamaji T, and Hanada K
    • Organizer
      Gordon Research Conference on Glycolipid and Sphingolipid Biology
    • Place of Presentation
      Ventura, CA, USA
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] Genetic approaches for studying sphingolipid metabolism: Construction of sphingolipid gene disruptants in HeLa cells by genome editing2014

    • Author(s)
      Yamaji T, Hanada K
    • Organizer
      6th Asian Community of Glycoscience and Glycotechnology
    • Place of Presentation
      Hyderabad, India
    • Year and Date
      2014-12-10
    • Data Source
      KAKENHI-PROJECT-26440069
  • [Presentation] TALEN-Mediated Disruption of Several Sphingolipid-Related Genes in a HeLa cell line2014

    • Author(s)
      Toshiyuki Yamaji and Kentaro Hanada
    • Organizer
      Gordon Research Conference on Glycolipid and Sphingolipid Biology
    • Place of Presentation
      Ventura, California, USA
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line."2014

    • Author(s)
      Yamaji T, Hanada K.
    • Organizer
      Gordon Research Conference on Glycolipid and Sphingolipid Biology
    • Place of Presentation
      Ventura, USA
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line2014

    • Author(s)
      Yamaji T, Hanada K
    • Organizer
      Gordon Research Conference on Glycolipid and Sphingolipid Biology
    • Place of Presentation
      Ventura, USA
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] アフリカミドリザル腎由来Vero細胞のゲノム構造決定2014

    • Author(s)
      花田賢太郎、山地俊之、黒田誠、関塚剛史、小原有弘、笠井文生、平山知子、長田直樹
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2014-10-17
    • Data Source
      KAKENHI-PROJECT-26440069
  • [Presentation] TALEN-Mediated Disruption of Several Sphingolipid-Related Genes in a HeLa cell line2014

    • Author(s)
      Toshiyuki Yamaji and Kentaro Hanada
    • Organizer
      Gordon Research Conference on Glycolipid and Sphingolipid Biology
    • Place of Presentation
      Ventura, CA, USA
    • Data Source
      KAKENHI-PROJECT-25670065
  • [Presentation] 人工ヌクレアーゼTALENを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第32回日本糖質学会大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-25670065
  • [Presentation] "人工ヌクレアーゼを利用したゲノム編集技術によるスフィンゴ脂質関連遺伝子破壊HeLa細胞変異株パネル作成の試み"2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第8回スフィンゴテラピィ研究会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 人工ヌクレアーゼを利用したゲノム編集技術によるスフィンゴ脂質関連遺伝子破壊HeLa細胞変異株パネル作成の試み2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第8回スフィンゴテラピー研究会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-25670065
  • [Presentation] 遺伝生化学的手法を用いたスフィンゴ糖脂質研究2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 遺伝生化学的手法を用いたスフィンゴ糖脂質研究2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line2013

    • Author(s)
      Yamaji, Y., Hanada, K.
    • Organizer
      54th International Conference on the Bioscience of Lipids
    • Place of Presentation
      Bari, Italy
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] "人工ヌクレアーゼTALENを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製"2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第32回日本糖質学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line2013

    • Author(s)
      Toshiyuki Yamaji and Kentaro Hanada
    • Organizer
      54th International Conference on the Bioscience of Lipids: Linking Transcription to Physiology in Lipidomics
    • Place of Presentation
      Bari, Italy
    • Data Source
      KAKENHI-PROJECT-25670065
  • [Presentation] 遺伝生化学的手法を用いたスフィンゴ糖脂質研究2013

    • Author(s)
      山地俊之, 花田賢太郎
    • Organizer
      第86回日生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] TALEN- Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line."2013

    • Author(s)
      Yamaji Y, Hanada K.
    • Organizer
      54^<th> International Conference on the Bioscience of Lipids
    • Place of Presentation
      Bari, Italy
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line2013

    • Author(s)
      Yamaji T, and Hanada K
    • Organizer
      54th International Conference on the Bioscience of Lipids : Linking Transcription to Physiology in Lipidomics
    • Place of Presentation
      Bari, Italy
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] 人工ヌクレアーゼTALENを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第32回日本糖質学会大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] Biding of Siglec-9 to the counter-receptors on cancer cells regulates adhesion dynamics via protease-mediated degradation of focal adhesion kinase (FAK)2013

    • Author(s)
      Yilihamujiang, S., Hashimoto, N., Matsumoto, Y., Hashimoto, Y., Yamaji, T., Furukawa, K., Furukawa, K.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] TALEN-Mediated Disruption of Sphingolipid-Related Genes in a HeLa Cell Line2013

    • Author(s)
      Toshiyuki Yamaji and Kentaro Hanada
    • Organizer
      54th International Conference on the Bioscience of Lipids: Linking Transcription to Physiology in Lipidomics
    • Place of Presentation
      Bari, Italy
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] "遺伝生化学的手法を用いたスフィンゴ糖脂質研究"2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 人工ヌクレアーゼを利用したゲノム編集技術によるスフィンゴ脂質関連遺伝子破壊HeLa細胞変異株パネル作成の試み2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第8回スフィンゴテラピー研究会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] "人工ヌクレアーゼを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製"2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第55回日本脂質生化学会
    • Place of Presentation
      松島
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 人工ヌクレアーゼを利用したゲノム編集技術によるスフィンゴ脂質関連遺伝子破壊:HeLa細胞変異株パネル作成の試み2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第8回スフィンゴテラピィ研究会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 人工ヌクレアーゼを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013

    • Author(s)
      山地俊之, 花田賢太郎
    • Organizer
      第55回日本脂質生化学会大会
    • Place of Presentation
      松島
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] 人工ヌクレアーゼを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第55回日本脂質生化学会
    • Place of Presentation
      松島
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] Biding of Siglec-9 to the counter-receptors on cancer cells regulates adhesion dynamics via protease-mediated degradation of focal adhesion kinase (FAK)."2013

    • Author(s)
      Yilihamujiang S, Hashimoto N, Matsumoto Y, Hashimoto Y, Yamaji T, Furukawa K, Furukawa K.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 人工ヌクレアーゼTALEN を用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013

    • Author(s)
      山地俊之, 花田賢太郎
    • Organizer
      第32回日本糖質学会大会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] 人工ヌクレアーゼTALENを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第32回日本糖質学会年会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 人工ヌクレアーゼを用いた種々のスフィンゴ脂質関連遺伝子の変異株作製2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第55回日本脂質生化学会大会
    • Place of Presentation
      松島
    • Data Source
      KAKENHI-PROJECT-25670065
  • [Presentation] 人工ヌクレアーゼを利用したゲノム編集技術によるスフィンゴ脂質関連遺伝子破壊HeLa 細胞変異株パネル作成の試み2013

    • Author(s)
      山地俊之,花田賢太郎
    • Organizer
      第8回スフィンゴテラピー研究会
    • Place of Presentation
      加賀
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] 遺伝生化学的手法を用いたスフィンゴ糖脂質研究2013

    • Author(s)
      山地俊之、花田賢太郎
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25670065
  • [Presentation] "podocalyxin上のO-glycanは癌の免疫逃避を促進する"2012

    • Author(s)
      南部今日子、橋本登、伊藤静香、山地俊之、橋本康弘、古川圭子、古川鋼一
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] Structural basis for the preferential recognition of phosphatidylinositol 4-monophosphate by the pleckstrin homology domain of the ceramide trafficking protein CERT2012

    • Author(s)
      Hanada K, Sugiki T, Takeuchi K, Tokunaga, Y, Terasawa, H, Kumagai, K, Yamaji, T, Takahashi, H, Shimada, I
    • Organizer
      2012 ASBMB Special Symposium, Frontiers in Lipid Biology
    • Place of Presentation
      Banff, Canada
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] podocalyxin上のO-glycanは癌の免疫逃避を促進する2012

    • Author(s)
      南部今日子、橋本登、伊藤静香、山地俊之、橋本康弘、古川圭子、古川鋼一
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] Structural basis for the recognition of phosphatidylinositol 4-monophosphate by the pleckstrin homology domain of the ceramide trafficking protein CERT2012

    • Author(s)
      Kentaro Hanada, Toshihiko Sugiki, Koh Takeuchi, Yuji Tokunaga, Hiroaki Terasawa, Keigo Kumagai, Toshiyuki Yamaji, Hideo Takahashi, and Ichio Shimada
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] セラミド輸送タンパク質CERTのプレクストリン相同ドメインによるホスファチジルイノシトール4ーリン酸認識の構造基盤2012

    • Author(s)
      花田賢太郎、杉木俊彦、竹内恒、山地俊之、高野等覚、徳永祐二、熊谷圭吾、高橋栄夫、嶋田一夫
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 糖脂質再構成細胞における膜流動性と成長因子受容体の関連2012

    • Author(s)
      櫻井祐介、山地俊之、花田賢太郎、樺山一哉
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] "セラミド輸送タンパク質CERTのプレクストリン相同ドメインによるホスファチジルイノシトール4ーリン酸認識の構造基盤"2012

    • Author(s)
      花田賢太郎、杉木俊彦、竹内恒、山地俊之、高野等覚、徳永祐二、熊谷圭吾、高橋栄夫、嶋田一夫
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 糖脂質再構成細胞における膜流動性と成長因子受容体の関連2012

    • Author(s)
      櫻井祐介、山地俊之、花田賢太郎、樺山一哉
    • Organizer
      第85回日本生化学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] TMBIMファミリーの糖脂質生合成への影響とその制御機構2011

    • Author(s)
      山地俊之、西川喜代孝、花田賢太郎
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 糖鎖受容体Siglec-7を介する細胞死の分子機構の解明2011

    • Author(s)
      奈良清光、三ツ木元章、榎本綾子、菅野真由美、山口芳樹、二川了次、城谷圭朗、山地俊之、山田茜、和栗聡
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] Siglec-7 induces non-apoptotic cell death of U9372011

    • Author(s)
      Nara K, Mitsuki M, Yamaji T, Enomoto A, Kanno M, Yamaguchi Y, Yamada Y, Waguri S, Hashimoto Y.
    • Organizer
      The 31^<th> Naito Conference on Glycan expression and Regulation [II]
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 糖脂質再構成細胞における受容体活性と膜流動性の関連性の解析2011

    • Author(s)
      櫻井祐介、山地俊之、花田賢太郎、樺山一哉
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] TMBIMファミリーの糖脂質生合成への影響とその制御機構2011

    • Author(s)
      山地俊之、西川喜代孝、花田賢太郎
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23770164
  • [Presentation] 糖鎖受容体Siglec-7を解する細胞死の分子機構の解明2010

    • Author(s)
      奈良清光、三ツ木元章、榎本綾子、菅野真由美、山口芳樹、二川了次、城谷圭朗、山地俊之、山田茜、和栗聡
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010

    • Author(s)
      Yamaji, T., Nishikawa, K., Hanada, K.
    • Organizer
      The 28^<th> Naito Conference on Glycan Expression and Regulation [I]
    • Place of Presentation
      湘南国際村センター(神奈川県)
    • Year and Date
      2010-07-29
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010

    • Author(s)
      Yamaji, T., Nishikawa, K., Hanada, K.
    • Organizer
      The 28^<th> Naito Conference on Glycan Expression and Regulation[I]
    • Place of Presentation
      湘南
    • Year and Date
      2010-07-29
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010

    • Author(s)
      Yamaji T, Nishikawa T, and Hanada K
    • Organizer
      The 27th Naito Conference on Membrane Dynamics and Lipid Biology [I]
    • Place of Presentation
      Sapporo
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] Siglec-7を介したU937細胞の細胞死に必要な細胞外領域の同定" 日本生化学会東北支部2010

    • Author(s)
      奈良清光、菅野真由美、三ツ木元章、山地俊之、山口芳樹、和栗聡、橋本康弘
    • Organizer
      第76回例会・シンポジウム
    • Place of Presentation
      福島
    • Year and Date
      2010-05-08
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010

    • Author(s)
      Yamaji, T., Nishikawa, K., Hanada, K.
    • Organizer
      The 27^<th> Naito Conference on Membrane Dynamics and Lipid Biology [I]
    • Place of Presentation
      シャトレーゼガトーキンクダムサッポロ(北海道)
    • Year and Date
      2010-07-01
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] Siglec-7を介したU937細胞の細胞死に必要な細胞外領域の同定2010

    • Author(s)
      奈良清光、菅野真由美、三ツ木元章、山地俊之、山口芳樹、和栗聡、橋本康弘
    • Organizer
      日本生化学会東北支部 第76回例会・シンポジウム
    • Place of Presentation
      コラッセ福島(福島県)
    • Year and Date
      2010-05-08
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010

    • Author(s)
      Toshiyuki Yamaji
    • Organizer
      The 27^<th> Naito Conference on Membrane Dynamics and Lipid Biology [I]
    • Place of Presentation
      Sapporo, Hokkaido, Japan
    • Year and Date
      2010-07-01
    • Data Source
      KAKENHI-PROJECT-22370054
  • [Presentation] 糖鎖受容体Siglec-7を解する細胞死の分子機構の解明2010

    • Author(s)
      奈良清光、三ツ木元章、榎本綾子、菅野真由美、山口芳樹、二川了次、城谷圭朗、山地俊之、山田茜、和栗聡
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会
    • Place of Presentation
      神戸ポートアイランド(兵庫県)
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] Globotriaosylceramide (Gb3) is reduced by the expression of hydrophobic polypeptides including TMBIM family : Isolation of Shiga toxin-resistant genes2010

    • Author(s)
      Yamaji, T., Nishikawa, K., Hanada, K.
    • Organizer
      The 27^<th> Naito Conference on Membrane Dynamics and Lipid Biology [I]
    • Place of Presentation
      札幌
    • Year and Date
      2010-07-01
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] 志賀毒素耐性遺伝子の単離2009

    • Author(s)
      山地俊之、西川喜代孝、花田賢太郎
    • Organizer
      第29回日本糖質学会年会
    • Place of Presentation
      高山
    • Year and Date
      2009-09-11
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] 志賀毒素耐性遺伝子の単離2009

    • Author(s)
      山地俊之、西川喜代孝、花田賢太郎
    • Organizer
      第82回日本生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] Binding specificity of siglec-7 prepared from various animal cell lines2009

    • Author(s)
      Ito, S., Ito, N., Tsuchida, A., Tokuda, N., Yagi, H., Kato, K., Mitsuki, M., Yamaji, T., Hashimoto, Y., Crocker, P.R., Furukawa K.
    • Organizer
      第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-12-10
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] Binding specificity of siglec-7 prepared from various animal cell lines2008

    • Author(s)
      Ito, S., Ito, N., Tsuchida, A., Tokuda, N., Yagi, H., Kato, K., Mitsuki, M., Yamaji, T., Hashimoto, Y., Crocker, P. R., and Furukawa K.
    • Organizer
      日本分子生物学会年会・日本生化学会大会合同大会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20770114
  • [Presentation] アフリカミドリザル腎由来Vero細胞のゲノム構造決定

    • Author(s)
      花田賢太郎、山地俊之、黒田誠、関塚剛史、小原有弘、笠井文生、平山知子、長田直樹
    • Organizer
      第87回日本生化学会大会
    • Place of Presentation
      京都市
    • Year and Date
      2014-10-15 – 2014-10-18
    • Data Source
      KAKENHI-PROJECT-25670065
  • 1.  HANADA KENTARO (30192701)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 29 results
  • 2.  SAITO Kyoko (70235034)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  KUMAGAI Keigo (40443105)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  SUGIKI Toshihiko (70635698)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  FUKASAWA Masayoshi (20291130)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  SAKUMA Chisato (80782888)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  石井 克幸 (90342899)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  関塚 剛史 (40462775)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  谷田 以誠 (30296868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  KABAYAMA Kazuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  SAKUMA Keiichiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  OSADA Naoki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 13.  SUZUKI Noriko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  HISHIKI Takayuki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  真鍋 良幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  深瀬 浩一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  神奈木 玲児
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  河村 由紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  土肥 多恵子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  竹内 恒
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  八尋 錦之助
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  黒田 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  齋藤 恭子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  脇田 隆字
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 25.  古川 圭子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  古川 鋼一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  黒川 量雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  中野 明彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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