OHSHIRO Kazufumi 大城和文

Researcher Number	50332648
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2004: 新潟大, 医歯(薬)学総合研究科, 助手 2001 – 2004: NIIGATA UNIVERSITY, Graduate School of Medical and Dental Sciences, Assistant, 大学院・医歯学総合研究科, 助手 2001: 新潟大学, 大学院・医歯学総合研究科, 助教授
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Morphological basic dentistry Except Principal Investigator Morphological basic dentistry / Morphological basic dentistry / 病態科学系歯学(含放射線系歯学) / Pathobiological dentistry/Dental radiology / Biological Sciences
Keywords	Principal Investigator 免疫染色 / ペプチド抗体 / 毛細血管 / 口腔腫瘍 / 選択的スプライシング / ヘパラン硫酸プロテオグリカン / パールカン / in-situハイブリダイゼーション / アンチセンス法 / RT-PCR / 培養細胞 … More Except Principal Investigator … More RT-PCR / 細胞外基質 / PCR / 細胞培養 / in-situハイブリダイゼーション / salivary gland tumor / EBV / 口腔癌 / リンパ球 / 噛みたばこ / 歯科補綴物 / 病理疫学 / 前癌病変 / 表在型扁平上皮癌 / アジア民族 / SSCP / DNA / p53 / cell culture / 唾液腺腫瘍 / extracellular matrix / ヘパラン硫酸プロテオグリカン / 口腔粘膜癌 / DNAチップ / 免疫組織化学 / oral cancer / マイクロディセクション / 噛みタバコ / 異型上皮 / microdissection / squamous cell carcinoma / マイクロディセクション法 / 扁平上皮癌 / gene mutation / cancer suppressor gene / 遺伝子変異 / LMP1 gene / lymphoepithelial carcinoma / 中国 / DNAシークエンス / リンパ上皮腫 / integrin / スラミン / 抗腫瘍効果 / ACC3 / 細胞接着 / インテグリン / パールカン / がん遺伝子 / capsular invasion / DNA sequencing / DNA tip / mutation of oncogene / karyotyping analyses / melanotic neuroectodermal tumor / pleomorphic adenoma / がん関連遺伝子 / 顎骨石灰化歯原性曩胞 / VEGF / 低酸素 / 染色体転座 / 脈管侵襲 / 唾液腺多形性腺腫 / 被膜浸潤 / がん遺伝子変異 / 染色体解析 / 黒色プロゴノーマ / 多形性腺腫 / benign lymphoepithelial lesion / lymphoepithelial cyst / cloning / salivary gland / NF-kB / 塩基配列決定 / 遺伝子導入 / リンパ上皮性癌 / 良性リンパ上皮性病変 / リンパ上皮性嚢胞 / 株化 / LMP1遺伝子 / 唾液腺 / transgenic mouse / lymphocyte / intraepithelial stroma / perlecan / oral mucosa / tooth germ / skin / epithelium / ヘパラン硫酸鎖 / 口腔粘膜疾患 / 正常口腔粘膜上皮 / トランスジェニックマウス / 創傷治癒 / 歯胚 / 皮膚 / 口腔粘膜上皮 / pathological epidemiology / chewing tobacco / extracellu matrix / submucosal fibrosis / epithelial dysplasia / carcinoma in-situ / Asia / OSF / 口腔がん / 口腔粘膜下線維症 / 上皮内癌 / sequencing / 細胞外基質分子 / 細胞外基質分解酵素MMP / 転移形質 / in-situ hybridization / interstitial cells / co-culture / tumor stroma / リアルタイムPCR / 癌細胞 / 線様嚢胞癌 / In-situハイブリダイゼーション / in-situハイブリダイゼー / 間質細胞 / 細胞共培養 / 腫瘍間質 / pathologic epidemiology / chew tobacco / orthoprosthesis / dysplasia / pre-cancer / superficial squamous cell carcinoma / Asia nation / 南アジア / 東アジア / 表在癌 / 癌関連遺伝子 / アポトーシス / DNA chip analysis / suramin / DNAチップ法 / ライソゾーム / ノパラン硝酸プロテオグルカン / マイクロダイセクション / DNAチップ解析 / sequecing / 血管分布 / 塩基配列解析 / 癌抑制遺伝子 / carcinogenetic mutations / gene polymorphism / ロシア / 30bp欠損 / LMP-1 / 発癌性変異 / 遺伝子多様性 / LMP-1遺伝子 / anti-cancer strategy / focal adhesion kinase / cell adhesion / fibronectin / heparan sulfate proteoglycan / RGDペプチド / 焦点接触キナーゼ / ファイブロネクチン / 活性化試験 / リンパ球培養 / 口腔粘膜異型上皮 / 基質合成 / 細胞遊走 / リンパ球活性化 / マクロファージ / 正常人末梢血 / エナメル上皮腫 / 上皮内基質 / テネイシン / 口腔粘膜 Less

Molecular biologic and pathologic analysis of Epstein-Barr virus infection related salivary lymphoepithelial carcinoma
- Principal Investigator
  
  CHENG Jun
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Niigata University
Molecular pathological study of mechanism in malignant changes of oral benign tumors
- Principal Investigator
  
  CHENG Jun
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Niigata University
免疫担当細胞による細胞外基質分子の生合成とその意義-リンパ球・マクロファージの遊走機構基盤と間質改造現象への貢献-
- Principal Investigator
  
  朔敬
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Niigata University
口腔腫瘍におけるパールカン遺伝子スプライシング様式の意義Principal Investigator
- Principal Investigator
  
  大城和文
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Niigata University
Molecular pathological analysis of oral carcinoma caused by chewing habits in Asia
- Principal Investigator
  
  SAKU Takashi
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Niigata University
Molecular pathological analysis of intraepithelial distribution of extracellular matrix molecules
- Principal Investigator
  
  SUZUKI Makoto
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Niigata University
アジア民族の表在型口腔粘膜癌の発生に関する病理疫学的研究
- Principal Investigator
  
  程クン
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Niigata University
A new anti-cancer strategy by control ling crosstalk of oral carcinoma cells with extracellular matrix molecules
- Principal Investigator
  
  SAKU Takashi
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Niigata University
Metastasis-associated genes in salivary adenoid cystic carcinoma and oral squamous cell carcinoma : a differential DNA chip analysis between metastatic and non-metastatic cell systems
- Principal Investigator
  
  CHENG Jun
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  NIIGATA UNIVERSITY
口腔領域腫瘍の形成・増殖における基底膜型ヘパラン硫酸プロテオグリカンの役割Principal Investigator
- Principal Investigator
  
  大城和文
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Niigata University
口腔粘膜上皮層内に細胞外基質は存在するか
- Principal Investigator
  
  SAKU Takashi
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Niigata University
A new anti-cancer strategy by control ling cross talk of oral carcinoma cells with extra cellular matrix molecules
- Principal Investigator
  
  SAKU Takashi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Niigata University
Polymorphism in cancer-related genes among oral cancers from the eastern Asian area
- Principal Investigator
  
  CHENG Jun
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Niigata University
Molecular biologic and pathologic study of Epstein-Barr virus infected lymphepithalial carcinomas in salivary gland
- Principal Investigator
  
  SAKU Takashi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  NIIGATA UNIVERSITY
Mutational events of p53 gene in salivary gland tumors
- Principal Investigator
  
  CHENG Jun
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Niigata University
Anti-oral cancer strategy by means of inhibition of cellular adhesion to extracellula matrices
- Principal Investigator
  
  SAKU Takashi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  NIIGATA UNIVERSITY

All 2005 2004 2003 2002

All Journal Article

[Journal Article] Extracellular matrix remodeling in oral submiicous fibrosis : its stage-specific modes revealed by immunohistochemistry and in-situ hybridization2005
- Author(s)
  Utsunomiya H, Tilakaratne WM, Ohshiro K, Ida-Yonemochi H, Cheng J, Saku T
- Journal Title
  
  Journal of Oral Pathology & Medicine 2005 (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13576025
[Journal Article] Perlecan, a basement membrane type heparan sulfate proteoglycan, in the enamel organ : its intraepithelial localization in the stellate reticulum2005
- Author(s)
  Ida-Yonemochi H, Ohshiro K, Swelam W, Metwaly H, Saku T
- Journal Title
  
  Journal of Histochemistry & Cytochemistry 52(in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557157
[Journal Article] Vascular endothelial growth factor in salivary pleomorphic adenomas : one of the reasons for their poorly vascularized stroma.2005
- Author(s)
  Swelam W, Ida-Yonemochi H, Maruyama S, Ohshiro K, Cheng J, Saku T
- Journal Title
  
  Virshows Arch 446(6)
  
  Pages: 653-662
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370581
[Journal Article] Perlecan, a basement membrane type heparan sulfate proteoglycan, in the enamel organ : its intraepithelial localization in the stellate reticulum2005
- Author(s)
  Ida-Yonemochi H, Ohshiro K, Swelam W, Metwaly H, Saku T
- Journal Title
  
  Journal of Histochemistry & Cytochemistry 53(6)
  
  Pages: 763-772
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370581
[Journal Article] Perlecan, a basement membrane type heparan sulfate proteoglycan, in the enamel organ : its intraepithelial localization in the stellate reticulum2005
- Author(s)
  Ida-Yonemochi H, Ohshiro K, Swelam W, Metwaly H, Saku T
- Journal Title
  
  Journal of Histochemistry & Cytochemistry 52(in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591993
[Journal Article] Establishment and characterization of new cell lines derived from melanotic neuroectodermal tumor of infancy arising in the mandible.2005
- Author(s)
  Metwaly H, Cheng J, Maruyama S, Ohshiro K, Suzuki I, Hoshina Y, Saku T
- Journal Title
  
  Pathology International 55(6)
  
  Pages: 331-342
- NAID
  10019345357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591821
[Journal Article] Vascular endothelial growth factor in salivary pleomorphic adenomas : one of the reasons for their poorly vascularized stroma.2005
- Author(s)
  Swelam W, Ida-Yonemochi H, Maruyama S, Ohshiro K, Cheng J, Saku T
- Journal Title
  
  Virshows Arch 446(6)
  
  Pages: 653-662
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591821
[Journal Article] Establishment and characterization of new cell lines derived from melanotic neuroectodermal tumor of infancy arising in the mandible.2005
- Author(s)
  Metwaly H, Cheng J, Maruyama S, Ohshiro K, Suzuki I, Hoshina Y, Saku T
- Journal Title
  
  Patholgy International 55(6)
  
  Pages: 331-342
- NAID
  10019345357
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370581
[Journal Article] Extracellular matrix remodeling in oral submucous fibrosis : its stage-specific modes revealed by immunohistochemistry and in-situ hybridization2005
- Author(s)
  Utsunomiya H, Tilakaratne WM, Ohshiro K, Ida-Yonemochi H, Cheng J, Saku T
- Journal Title
  
  Journal of Oral Pathology & Medicine 34(8)
  
  Pages: 498-507
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370581
[Journal Article] Extracellular matrix remodeling in oral submucous fibrosis : its stage-specific modes revealed by immunohistochemistry and in-situ hybridization2005
- Author(s)
  Utsunomiya H, Tilakaratne WM, Ohshiro K, Ida-Yonemochi H, Cheng J, Saku T
- Journal Title
  
  Journal of Oral Pathology & Medicine 34(in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557157
[Journal Article] Intraepithelial expression of perlecan, a basement membrane-type heparan sulfate proteoglycan reflects dysplastic changes of the oral mucosal epithelium2004
- Author(s)
  Ikarashi T, Ida-Yonemochi H, Ohshiro K, Cheng J, Saku T
- Journal Title
  
  Journal of Oral pathology & Medicine 33(2)
  
  Pages: 87-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557157
[Journal Article] Intraepithelial expression of perlecan, a basement membrane-type heparan sulfate proteoglycan reflects dysplastic changes of the oral mucosal epithelium2004
- Author(s)
  Ikarashi T, Ida-Yonemochi H, Ohshiro K, Cheng J, Saku T
- Journal Title
  
  Journal of Oral pathology & Medicine 33(2)
  
  Pages: 87-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370581
[Journal Article] Intraepithelial expression of perlecan, a basement membrane-type heparan sulfate proteoglycan reflects dysplastic changes of the oral mucosal epithelium2004
- Author(s)
  Ikarashi T, Ida-Yonemochi H, Ohshiro K, Cheng J, Saku T
- Journal Title
  
  Journal of Oral Pathology & Medicine 33(2)
  
  Pages: 87-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591993
[Journal Article] The basement membrane type heparan sulfate proteoglycan, perlecan, produced by lymphocyte2004
- Author(s)
  Yamazaki M, Ohshiro K, Cheng J, Ida H, Kawamura H, Saku T
- Journal Title
  
  Proceedings of The Japanese Society of Pathology 93(1)
  
  Pages: 339-339
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591993
[Journal Article] Intraepithelial expression of perlecan, a basement membrane-type heparan sulfate proteoglycan reflects dysplastic changes of the oral mucosal epithelium2004
- Author(s)
  Ikarashi T, Ida-Yonemochi H, Ohshiro K, Cheng J, Saku T
- Journal Title
  
  Journal of Oral Pathology & Medicine 33(2)
  
  Pages: 87-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15256005
[Journal Article] Intraepithelial expression of perlecan, a basement membrane-type heparan sulfate proteoglycan reflects dysplastic changes of the oral mucosal epithelium2004
- Author(s)
  Ikarashi T, Ida-Yonemochi H, Ohshiro K, Cheng J, Saku
- Journal Title
  
  Journal of Oral Pathology & Medicine 33(2)
  
  Pages: 87-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13576025
[Journal Article] Vascular endothelial cell participation in formation of lymphoepithelial lesions (epi-myoepithelial islands) in lymphoepithelial sialadenitis (benign lymphoepithelial lesion)2003
- Author(s)
  Metwaly H, Cheng J, Ida-Yonemochi H, Ohshiro K, Jen KY, Liu AR, Saku T
- Journal Title
  
  Virchows Arch 443(1)
  
  Pages: 17-27
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557157
[Journal Article] Characterization for ECM molecules of two distinct types of the neoplastic stroma in oral SCC2003
- Author(s)
  Jen KY, Cheng J, Ohshiro K, Ida H, Ikarashi T, Saku T
- Journal Title
  
  Proceedings of The Japanese Society of Pathology 92(1)
  
  Pages: 361-361
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13576025
[Journal Article] Alternative splicing variants of perlecan, a basement membrane type heparan sulfate proteoglycan : their pathophysiological modes of expression in human oral cancer2003
- Author(s)
  Ohshiro K, Ohnuki N, Saku T
- Journal Title
  
  Proceedings of The Japanese Society of Pathology 92(1)
  
  Pages: 360-360
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13557157
[Journal Article] パールカン遺伝子の選択的スプライシング様式 -口腔がんにおける発現制御の検討-2003
- Author(s)
  大城和文
- Journal Title
  
  日本病理学会会誌 92(1)
  
  Pages: 360-360
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13557157
[Journal Article] Extracellular matrix remodeling in oral submucous fibrosis : its stage-specific modes revealed by immunohistochemistry and in-situ hybridization2002
- Author(s)
  Utsunomiya H, Tilakaratne WM, Ohshiro K, Ida-Yonemochi H, Cheng J, Saku T
- Journal Title
  
  Journal of Oral Pathology & Medicine 34(in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591993
[Journal Article] Extracellular matrix molecules in oral submucous fibrosis2002
- Author(s)
  Utsunomiya H, Cheng J, Ohshiro K, Tilakaratne WM, Saku T
- Journal Title
  
  Journal of Oral Biosciences 44(5)
  
  Pages: 167-167
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13576025

1. IDA Hiroko (60293213)

# of Collaborated Projects: 14 results

# of Collaborated Products: 0 results
2. SAKU Takashi (40145264)

# of Collaborated Projects: 14 results

# of Collaborated Products: 21 results
3. CHENG Jun (40207460)

# of Collaborated Projects: 14 results

# of Collaborated Products: 17 results
4. SUZUKI Makoto (50107778)

# of Collaborated Projects: 9 results

# of Collaborated Products: 1 results
5. MARUYAMA Satoshi (30397161)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. MIYAZAKI Hideo (00157629)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. NAKAJIMA Motowo

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. NAGAO Toru (90261007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 木村信 (80251825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 浅川義範 (50033874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 米持浩子

# of Collaborated Projects: 0 results

# of Collaborated Products: 17 results

OHSHIRO Kazufumi 大城 和文

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口腔領域腫瘍の形成・増殖における基底膜型ヘパラン硫酸プロテオグリカンの役割Principal Investigator

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OHSHIRO Kazufumi 大城和文