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NISHII Kazuhiro  西井 一浩

ORCIDConnect your ORCID iD *help
Researcher Number 50332713
Affiliation (based on the past Project Information) *help 2005 – 2006: 三重大学, 医学部附属病院, 助手
2002 – 2004: 三重大学, 医学部, 助手
2002: Mie University, Faculty of Medicine, Research Associate, 医学部附属病院, 助手
2001: 三重大学, 医学部・附属病院, 助手
Review Section/Research Field
Principal Investigator
Hematology / Hematology
Keywords
Principal Investigator
acute myeloid leukemia / mutation / tyrosine kinase / t(8;21) / c-kit / KIT / 予後因子 / 急性骨髄性白血病 / 遺伝子異常 / Ikaros … More / inv(16) / t(8;21) AML / point mutation / 骨髄異形性症候群 / inv(16) AML / t(8;21)AML / tyrosien kinase / abnormal chromosome / prognostic factor / inhibitor / 難治性白血病 / 染色体異常 / cancer / molecular biology / childhood / adult / acute lymphoblastic leukemia / transcription factor / acute leukemia / 分子生分学 / リンパ性白血病 / 発癌機構 / 白血病 / 発がん機構 / 分子生物学 / 小児 / 成人 / 急性リンパ性白血病 / 転写因子 / 急性白血病 Less
  • Research Projects

    (3 results)
  • Research Products

    (42 results)
  •  Characteristics of the leukemia with KIT mutationPrincipal Investigator

    • Principal Investigator
      NISHII Kazuhiro
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Mie University
  •  Active mutation of c-kit gene in acute myeloid leukemiaPrincipal Investigator

    • Principal Investigator
      NISHII Kazuhiro
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Mie University
  •  Expression of Ikaros isoforms in adult and childhood pre-B acute lymphoblastic leukemias.Principal Investigator

    • Principal Investigator
      NISHII Kazuhiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Mie University

All 2007 2006 2004 2003 Other

All Journal Article

  • [Journal Article] Successful treatment of imatinib combined with less intensive chemotherapy (vincristine and dexamethasone) as induction therapy in a very elderly patient with Philadelphia chromosome-positive acute lymphoblastic leukienmia.2007

    • Author(s)
      Nishii K, Sakakura M, Tsukada T, Ryuu H, Katayama N
    • Journal Title

      International Journal of Hematology 85

      Pages: 273-274

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Detection of CBFB/MYH11 fusion gene in acute myeloid leukemia (AML) without inv(16); incidence in 218 Japanese AML cases.2007

    • Author(s)
      Monma F, Nishii K, Shiga J, Sugahara H, Watanabe Y, Kawakami K, Hosokai N, Yamamori S, Shiku H, Katayama N
    • Journal Title

      Leukemia Research 31

      Pages: 471-476

    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Expression of the JAK2 V617F mutation is not found in de novo AML and MDS but is detected in MDS-derived leukemia of megakaryoblastic nature.2007

    • Author(s)
      Nishii K, Nanbu R, Lorenzo F 5^<th>, Monma F, et al.
    • Journal Title

      Leukemia 21

      Pages: 1337-1338

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Detection of CBFB/MYH11 fusion gene in acute myeloid leukemia (AML) without inv(16); incidence in 218 Japanese AML cases.2007

    • Author(s)
      Monma F, Nishii K., Shiga J, Sugahara H, Watanabe Y, et al.
    • Journal Title

      Leukemia Research 31

      Pages: 471-476

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Expression of the JAK2 V617F mutation is not found in de novo AML and MDS but is detected in MDS-derived leukemia of megakaryoblastic nature.2007

    • Author(s)
      Nishii K, Nanbu R, Lorenzo F 5th, Monma F, Kato K, Ryuu H, Katayama N
    • Journal Title

      Leukemia 21

      Pages: 1337-1338

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Successful treatment of imatinib combined with less intensive chemotherapy (vincristine and dexamethasone) as induction therapy in a very elderly patient with Philadelphia chromosome-positive acute lymphoblastic leukemia.2007

    • Author(s)
      Nishii K, Sakakura M, tsukada T, Hyuu R, Katayama N
    • Journal Title

      Int J Hematol 85

      Pages: 273-274

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Detection of CBFB/MYH11 fusion gene in acute myeloid leukemia (AML) without inv(16); incidence in 218 Japanese AML cases.2007

    • Author(s)
      Monma F, Nishii K, Shiga J, Sugahara H, Watanabe y Kawakami K, Hosokai N, Yamamori S, Shiku H, Katayama N
    • Journal Title

      Leuk Res 31

      Pages: 471-476

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Molecular and phenatypic analysis of Philadelphia chromosome-positive bilineage leukemia : possibility of a lineage switch from T-lymphoid leukemic progenitor to myeloid cells.2006

    • Author(s)
      Monma F, Nishii K, Ezuki S, Miyazaki T, Yamamori S, Usui E, Sugimoto Y, et al.
    • Journal Title

      Cancer genetics and Cytogenetics 164

      Pages: 118-121

    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Granulocytic sarcoma of mesentery in acute myeloid leukemia with CBFB/MYH11 fusion gene but not inv(16) chromosome : case report and review of literature.2006

    • Author(s)
      Fujieda A, Nishii K, Tamaru T, Otsuki S, Kobayasi K, Monma F, Ohishi K, Nakase K, Katayama N, Shiku H
    • Journal Title

      Leuk Res 30

      Pages: 1053-1057

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Mutational analysis of the KIT gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia.2006

    • Author(s)
      Lorenzo F 5^<th>, Nishii K, Monma F, Kuwagata S, Usui E, Shiku H
    • Journal Title

      Leukemia Research 30

      Pages: 1235-1239

    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Molecular analysis of PDGFRA/B genes in core binding factor leukemia with eosinophilia.2006

    • Author(s)
      Monma F, Nishii K, Lorenzo F 5th, Usui E, Ueda Y, Katayama N, et al.
    • Journal Title

      European Journal of Hematology 76

      Pages: 18-22

    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Granulocytic sarcoma of mesentery in acute myeloid leukemia with CBFB/MYH11 fusion gene but not inv(16) chromosome : case report and review of literature.2006

    • Author(s)
      Fujieda A, Nishii K, Tamaru T, Otsuki S, Kobayasi K, Monma F, Ohishi K, NakaseK, Katayama N, Shiku H
    • Journal Title

      Leukemia Research 30

      Pages: 1053-1057

    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Granulocytic sarcoma of mesentery in acute myeloid leukemia with CBFB/MYH11 fusion gene but not inv(16) chromosome : case report and review of literature.2006

    • Author(s)
      Fujieda A, Nishii K., Tamaru T, Otsuki S, Kobayasi K, et al.
    • Journal Title

      Leukemia Research 30

      Pages: 1053-1057

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Low p53 expression of acute myelocytic leukemia cells with t(8;21) chromosome abnormality : Association with low p14(ARF) expression.2006

    • Author(s)
      Shikami M, Miwa H, Nishii K, Kyo T, Tanaka I, Shiku H, Kita K, Nitta M
    • Journal Title

      Leukemia Research 30

      Pages: 379-383

    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Molecular analysis of PDGFRα/β genes in core binding factor leukemia with eosinophilia.2006

    • Author(s)
      Monma F, Nishii K, Lorenzo F 5th, Usui E, Ueda Y, Katayama N, Watanabe Y, Kawakami k, Oka K, Mitani H, Sekine T, Tamaki S, Mizutani M, Yagasaki F, Doki N, Miyawaki S, Shiku H
    • Journal Title

      Eur J Haematol 76

      Pages: 18-22

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Mutational analysis of the KIT gene in myelodysplastic syndrome (MDS) and MDS-derived leukemia.2006

    • Author(s)
      Lorenzo F 5th, Nishii K, Monma F, Kuwagata S, Usui E, Shiku H
    • Journal Title

      Leuk Res 30

      Pages: 1235-1239

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Molecular analysis of PDGFRα/β genes in core binding factor leukemia with eosinophilia.2006

    • Author(s)
      Monma F, Nishii K, Lorenzo F 5th, Usui E, Ueda Y, Katayama N, et al.
    • Journal Title

      European Journal of Haematology 76

      Pages: 18-22

    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Molecular analysis of PDGFRA/B genes in core binding factor leukemia with eosinophilia.2006

    • Author(s)
      Monma F, Nishii K, Lorenzo F 5th, Usui E, Ueda Y, et al.
    • Journal Title

      European Journal of Hematology 76

      Pages: 18-22

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Up-regulated production of IL-6, but not IL-10, by Interferon-□□□induces SOCS3 expression and attenuates STAT1 phosphorylation in myeloma cells.2004

    • Author(s)
      Usui E, Nishii K, Katayama N, et al.
    • Journal Title

      Hematology J 5

      Pages: 505-512

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Up-regulated production of IL-6, but not IL-10, by Interferon- □induces SOCS3 expression and attenuates STAT1 phosohorylation in mveloma cells.2004

    • Author(s)
      Usui E, Nishii K, et al.
    • Journal Title

      Haematologica / Hematology J 5

      Pages: 505-512

    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Activities of granulocyte-macrophage colony-stimulating factor and interleukein-3 on monocytes2004

    • Author(s)
      Suzuki H, Katayama N, Ikuta Y, Mukai K, Fujita A, Mitani H, Araki H, Miyashita H, Hoshino N, Nishikawa H, Nishii K, et al.
    • Journal Title

      Am J Hematol 75

      Pages: 179-189

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Reprogramming of human post-mitotic neutrophils into macrophages by growth factors.2004

    • Author(s)
      Araki H, Katayama N, Yamashita Y, Mano H, Fujieda A, Usui E, Mitani H, Ohishi K, Nishii K, et al.
    • Journal Title

      Blood 103

      Pages: 2973-2980

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Case of chronic-phase chronic myelogenous leukemia with an abdominal hematopoietic tumor of leukemic clone origin.2004

    • Author(s)
      Sakakura M, OhishiK, Nomura K, Katayama N, Nishii K, et al.
    • Journal Title

      Am J Hematol 77

      Pages: 157-170

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Hemostatic abnormalities and changes following bone marrow transplantation.2004

    • Author(s)
      Matsumoto T, Wada H, Nishiyama H, Hirano T, Sakakura M, Nishii K, et al.
    • Journal Title

      Clin Appl Thromb Hemost 10

      Pages: 341-350

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Acute myeloid leukemia with t(8;21)(q22;q22) manifesting as granulocytic sarcomas in the rhinopharynx at relapse after high-dose cytarabine consolidation : case report and review of the literature.2004

    • Author(s)
      Sugimoto Y, Nishii K, Sakakura M, et al.
    • Journal Title

      Hematology J 5

      Pages: 84-89

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] CD21S antigen expression in tumor cells of diffuse large B-cell lymphomas is an independent prognostic factor indicating better overall survival.2004

    • Author(s)
      Ogawa S, Yamaguchi M, Oka K, Taniguchi M, Ito M, Nishii K, et al.
    • Journal Title

      Br J Haematol 125

      Pages: 180-186

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Up-regulated production of IL-6, but not IL-10, by Interferon-a induces SOCS3 expression and attenuates STAT1 phosphorylation in myeloma cells.2004

    • Author(s)
      Usui E, Nishii K, Katayama N, et al.
    • Journal Title

      Hematology J 5

      Pages: 505-512

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Acute myeloid leukemia with t(8;21)(q22;q22) manifesting as granulocytic sarcomas in the rhinopharynx at relapse after high-dose cytarabine consolidation ; case report and review of the literature.2004

    • Author(s)
      Sugimoto Y, Nishii K, et al.
    • Journal Title

      Haematologica / Hematology J 5

      Pages: 84-89

    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] AML with t(8;21) and trisomy 4 : possible involvement of c-kit?/Reply to SE Langabeer et al.2003

    • Author(s)
      Lorenzo F V, Nishii K, et al.
    • Journal Title

      Leukemia 17

      Pages: 1915-1916

    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Identification of signature genes by microarray for acute myeloid leukemia without maturation and acute promyelocytic leukemia with t(15;17)(q22;q12)(PML/RARA□).2003

    • Author(s)
      Morikawa J, Li H, Kim S, Nishii K, et al.
    • Journal Title

      Int J Oncol 23

      Pages: 617-625

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Characteristics of t(8;21) acute myeloid leukemia(AML) with additional chromosomal abnormality : Concomitant trisomy 4 may constitute a distinctive subtype of t(8;21) AML.2003

    • Author(s)
      Nishii K, Usui E, Katayama N, et al.
    • Journal Title

      Leukemia 17

      Pages: 731-737

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Characteristics of t(8;21) acute myeloid leukemia (AML) with additional chromosomal or abnormality : Concomitant trisomy 4 may constitute a distinctive subtype of t(8;21;21) AML2003

    • Author(s)
      Nishii K, Usui E, et al.
    • Journal Title

      Leukemia 17

      Pages: 731-737

    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Dual mutations in the AML1 and FLT3 genes are associated with leukemogenesis in acute myeloblastic leukemia for the M0 subtype.2003

    • Author(s)
      Matsuno N, Osato M, Yamashita N, Yanagida M, Nanri T, Fukushima T, Motoji T, Kusumoto S, Towatari M, Suzuki R, Naoe T, Nishii K, et al.
    • Journal Title

      Leukemia 17

      Pages: 2492-2499

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Hypermethylation of death-associated protein (DAP) kinase CpG island is frequent not only in B-cell but also in T-cell and natural killer (NK)/T-cell malignancies.2003

    • Author(s)
      Nakatsuka S-I, Takakuwa T, Tomita Y, Hoshida Y, Nishiu M, Yamaguchi M, Nishii K, Yang W-I, Aozasa K
    • Journal Title

      Cancer Sci 94

      Pages: 87-91

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] AML with t(8;21) and trisomy 4 : possible involvement of c-kit? / Reply to SE Langabeer et al.2003

    • Author(s)
      Lorenzo F V, Nishii K. Usui E, et al.
    • Journal Title

      Leukemia 17

      Pages: 1915-1916

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] AML with t(8;21) and trisomy 4 : possible involvement of c-kit?2003

    • Author(s)
      Lorenzo FV, Nishii K, Usui E, et al.
    • Journal Title

      Leukemia(Reply to SE Langabeer et al.) 17

      Pages: 1915-1916

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Characteristics of t(8;21) acute myeloid leukemia (AML) with additional chromosomal abnormality : Concomitant trisomy 4 may constitute a distinctive subtype of t(8;21) AML.2003

    • Author(s)
      Nishii K, Usui E, Katayama N, et al.
    • Journal Title

      Leukemia 17

      Pages: 731-737

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591002
  • [Journal Article] Mutational analysis of the KIT gene in myelodysplastic syndrome(MDS) and MDS-derived leukemia.

    • Author(s)
      Lorenzo F 5^<th>, Nishii K, Monma F, Kuwagata S, Usui E, Shiku H
    • Journal Title

      Leukemia Research (in press)

    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Granulocytic sarcoma of mesentery in acute myeloid leukemia with CBFB/MYH11 fusion gene but not inv(16) chromosome : case report and review of literature.

    • Author(s)
      Fujieda A, Nishii K, Tamaru T, Otsuki S, Kobayasi K, Monma F, Ohishi K, Nakase K, Katayama N, Shiku H
    • Journal Title

      Leukemia Research (in press)

    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Successful treatment of imatinib combined with less intensive chemotherapy (vincristine and dexamethasone) as induction therapy in a very elderly patient with Philadelphia chromosome-positive acute Iymphoblastic leukemia.

    • Author(s)
      Nishii K, Sakakura M, tsukada T, Ryuu H, Katayama N
    • Journal Title

      International Journal of Hematology (in press)

    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Bilateral osteonecrosis of the head of the femur in a young patient with acute promyelocytic leukemia during treatment with retinoic acid.

    • Author(s)
      Sakakura M, Nishii K, Usui E, Monma F, Tsukada T, Shiku H
    • Journal Title

      Internal Journal Hematology (in press)

    • Data Source
      KAKENHI-PROJECT-17590992
  • [Journal Article] Expression of the JAK2 V617F mutation is not found in de novo AML and MDS but is detected in MDS-derived leukemia of megakaryoblastic nature.

    • Author(s)
      Nishii K, Nanbu R, Lorenzo F 5^<th>, Monma F, Kato K, Ryuu H, Katayama N
    • Journal Title

      Leukemia (in press)

    • Data Source
      KAKENHI-PROJECT-17590992

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