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Iwawaki Takao  岩脇 隆夫

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IWAWAKI Takao  岩脇 隆夫

岩脇 隆夫  イワワキ タカオ

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Researcher Number 50342754
Other IDs
Affiliation (Current) 2022: 金沢医科大学, 総合医学研究所, 教授
Affiliation (based on the past Project Information) *help 2018 – 2021: 金沢医科大学, 総合医学研究所, 教授
2016: 金沢医科大学, 総合医学研究所, 教授
2015: 群馬大学, 医学(系)研究科(研究院), 講師
2011 – 2014: 群馬大学, 先端科学研究指導者育成ユニット, 講師
2010: The Institute of Physical and Chemical Research, 中野生体膜研究室, 客員主管研究員 … More
2009: The Institute of Physical and Chemical Research, 岩脇独立主幹研究ユニット, ユニットリーダー(独立主幹研究員)
2003: 理研, 研究員
2002: 理化学研究所, 細胞修復機構研究チーム, 基礎科学特別研究員 Less
Review Section/Research Field
Principal Investigator
General physiology / Biological Sciences / Neurochemistry/Neuropharmacology / Environmental physiology(including physical medicine and nutritional physiology) / Basic Section 42040:Laboratory animal science-related / Basic Section 59020:Sports sciences-related
Keywords
Principal Investigator
小胞体ストレス / タンパク質品質管理 / IRE1 / 炎症 / GFP / XBP1 / トランスジェニックマウス / 血管新生 / 胎盤 / 膵臓 … More / 糖尿病 / 唾液腺 / 小胞体ストレス応答 / インスリン / 抗体産生 / 動脈硬化 / RNA / 妊娠 / 小胞体シャペロン / RNase / 異常タンパク質 / IRE1 / PERK / 分子シャペロン / 天然変性タンパク質 / 酸化ストレス / 脂質代謝 / ガン / 炎症性腸疾患 / 癌 / ムチン / ATF4 / エリスロポエチン / 過食 / 細胞ストレス / 生体イメージング / 疾患モデル / 老化モデル / 疲労 / ストレス / 睡眠 / 運動 Less
  • Research Projects

    (8 results)
  • Research Products

    (119 results)
  • Co-Researchers

    (30 People)
  •  細胞ストレスと炎症の発展的研究から迫る「疲労」メカニズムの分子細胞生物学的な解明Principal Investigator

    • Principal Investigator
      岩脇 隆夫
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Kanazawa Medical University
  •  Transgenic mice for imaging of cellular stress associated with diseases and agingPrincipal Investigator

    • Principal Investigator
      IWAWAKI Takao
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 42040:Laboratory animal science-related
    • Research Institution
      Kanazawa Medical University
  •  Molecular mechanism of overeating regulated by cellular stress responsePrincipal Investigator

    • Principal Investigator
      IWAWAKI Takao
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Environmental physiology(including physical medicine and nutritional physiology)
    • Research Institution
      Kanazawa Medical University
      Gunma University
  •  異常タンパク質インターフェイスとしての天然変性領域の機能解析Principal Investigator

    • Principal Investigator
      岩脇 隆夫
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  Physiological and Pathological Function of Cellular Stress ResponsesPrincipal Investigator

    • Principal Investigator
      IWAWAKI Takao
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General physiology
    • Research Institution
      Gunma University
  •  「天然」変性タンパク質による「非天然」変性タンパク質の感知・認識機構の解析Principal Investigator

    • Principal Investigator
      岩脇 隆夫
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
      The Institute of Physical and Chemical Research
  •  Identification of novel ER stress responsive pathways that function in intercellular interactionPrincipal Investigator

    • Principal Investigator
      IWAWAKI Takao
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General physiology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  小胞体ストレス細胞死における分子制御機構の解明Principal Investigator

    • Principal Investigator
      岩脇 隆夫
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      The Institute of Physical and Chemical Research

All 2020 2019 2018 2017 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Patent

  • [Journal Article] IRE1α regulates macrophage polarization, PD-L1 expression, and tumor survival2020

    • Author(s)
      Batista Alyssa、Rodvold Jeffrey J.、Xian Su、Searles Stephen C.、Lew Alyssa、Iwawaki Takao、Almanza Gonzalo、Waller T. Cameron、Lin Jonathan、Jepsen Kristen、Carter Hannah、Zanetti Maurizio
    • Journal Title

      PLOS Biology

      Volume: 18

    • DOI

      10.1371/journal.pbio.3000687

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] AAV-mediated ERdj5 overexpression protects against P23H rhodopsin toxicity2020

    • Author(s)
      Aguila Monica、Bellingham James、Athanasiou Dimitra、Bevilacqua Dalila、Duran Yanai、Maswood Ryea、Parfitt David A、Iwawaki Takao、Spyrou Giannis、Smith Alexander J、Ali Robin R、Cheetham Michael E
    • Journal Title

      Human Molecular Genetics

      Volume: 29 Pages: 1310-1318

    • DOI

      10.1093/hmg/ddaa049

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Transgenic mouse model exhibiting weak red fluorescence before and strong green fluorescence after Cre/loxP-mediated recombination2020

    • Author(s)
      Akai Ryoko、Saito Michiko、Kohno Kenji、Iwawaki Takao
    • Journal Title

      Experimental Animals

      Volume: 69 Pages: 306-318

    • DOI

      10.1538/expanim.19-0085

    • NAID

      130007884759

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] IRE1α Promotes Zika Virus Infection via XBP12020

    • Author(s)
      Kolpikova Elena P.、Tronco Ana R.、Den Hartigh Andreas B.、Jackson Konner J.、Iwawaki Takao、Fink Susan L.
    • Journal Title

      Viruses

      Volume: 12 Pages: 278-278

    • DOI

      10.3390/v12030278

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Protective effect of dimethyl fumarate for the development of pressure ulcers after cutaneous ischemia‐reperfusion injury2020

    • Author(s)
      Inoue Yuta、Uchiyama Akihiko、Sekiguchi Akiko、Yamazaki Sahori、Fujiwara Chisako、Yokoyama Yoko、Ogino Sachiko、Torii Ryoko、Hosoi Mari、Akai Ryoko、Iwawaki Takao、Ishikawa Osamu、Motegi Sei‐ichiro
    • Journal Title

      Wound Repair and Regeneration

      Volume: 28 Pages: 600-608

    • DOI

      10.1111/wrr.12824

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Protein quality control through endoplasmic reticulum-associated degradation maintains haematopoietic stem cell identity and niche interactions2020

    • Author(s)
      Xu Longyong、Iwawaki Takao、Chen Xi et al
    • Journal Title

      Nature Cell Biology

      Volume: 22 Pages: 1162-1169

    • DOI

      10.1038/s41556-020-00581-x

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Apelin/APJ signaling suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model2020

    • Author(s)
      Yamazaki Sahori、Sekiguchi Akiko、Uchiyama Akihiko、Fujiwara Chisako、Inoue Yuta、Yokoyama Yoko、Ogino Sachiko、Torii Ryoko、Hosoi Mari、Akai Ryoko、Iwawaki Takao、Ishikawa Osamu、Motegi Sei-ichiro
    • Journal Title

      Scientific Reports

      Volume: 10 Pages: 1349-1349

    • DOI

      10.1038/s41598-020-58452-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Role of IRE1α in podocyte proteostasis and mitochondrial health2020

    • Author(s)
      Navarro-Betancourt Jos? R.、Papillon Joan、Guillemette Julie、Iwawaki Takao、Chung Chen-Fang、Cybulsky Andrey V.
    • Journal Title

      Cell Death Discovery

      Volume: 6 Pages: 128-128

    • DOI

      10.1038/s41420-020-00361-4

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] ERdj5 in Innate Immune Cells Is a Crucial Factor for the Mucosal Adjuvanticity of Cholera Toxin2019

    • Author(s)
      Kim MS, Yi EJ, Kim YI, Kim SH, Jung YS, Kim SR, Iwawaki T, Ko HJ, Chang SY
    • Journal Title

      Front Immunol

      Volume: 10 Pages: 1249-1249

    • DOI

      10.3389/fimmu.2019.01249

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Zinc deficiency exacerbates pressure ulcers by increasing oxidative stress and ATP in the skin2019

    • Author(s)
      Nakamura H, Sekiguchi A, Ogawa Y, Kawamura T, Akai R, Iwawaki T, Makiguchi T, Yokoo S, Ishikawa O, Motegi SI
    • Journal Title

      J Dermatol Sci

      Volume: 95 Pages: 62-69

    • DOI

      10.1016/j.jdermsci.2019.07.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-19K21517
  • [Journal Article] Adaptive endoplasmic reticulum stress signalling via IRE1α-XBP1 preserves self-renewal of haematopoietic and pre-leukaemic stem cells2019

    • Author(s)
      Liu L, Zhao M, Jin X, Ney G, Yang KB, Peng F, Cao J, Iwawaki T, Del Valle J, Chen X, Li Q
    • Journal Title

      Nat Cell Biol

      Volume: 21 Pages: 328-337

    • DOI

      10.1038/s41556-019-0285-6

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Salmonella exploits HLA-B27 and host unfolded protein responses to promote intracellular replication2019

    • Author(s)
      Antoniou AN, Lenart I, Kriston-Vizi J, Iwawaki T, Turmaine M, McHugh K, Ali S, Blake N, Bowness P, Bajaj-Elliott M, Gould K, Nesbeth D, Powis SJ
    • Journal Title

      Ann Rheum Dis

      Volume: 78 Pages: 74-82

    • DOI

      10.1136/annrheumdis-2018-213532

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] IRE1α-XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain2019

    • Author(s)
      Chopra S, Giovanelli P, Alvarado-Vazquez PA, Alonso S, Song M, Sandoval TA, Chae CS, Tan C, Fonseca MM, Gutierrez S, Jimenez L, Subbaramaiah K, Iwawaki T, Kingsley PJ, Marnett LJ, Kossenkov AV, Crespo MS, Dannenberg AJ, Glimcher LH, Romero-Sandoval EA, Cubillos-Ruiz JR
    • Journal Title

      Science

      Volume: 365

    • DOI

      10.1126/science.aau6499

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] IRE1α Activation in Bone Marrow-Derived Dendritic Cells Modulates Innate Recognition of Melanoma Cells and Favors CD8+ T Cell Priming2019

    • Author(s)
      Medel B, Costoya C, Fernandez D, Pereda C, Lladser A, Sauma D, Pacheco R, Iwawaki T, Salazar-Onfray F, Osorio F
    • Journal Title

      Front Immunol

      Volume: 9 Pages: 3050-3050

    • DOI

      10.3389/fimmu.2018.03050

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Danger-associated extracellular ATP counters MDSC therapeutic efficacy in acute GVHD2019

    • Author(s)
      Koehn BH, Saha A, McDonald-Hyman C, Loschi M, Thangavelu G, Ma L, Zaiken M, Dysthe J, Krepps W, Panthera J, Hippen K, Jameson SC, Miller JS, Cooper MA, Farady CJ, Iwawaki T, Ting JP, Serody JS, Murphy WJ, Hill GR, Murray PJ, Bronte V, Munn DH, Zeiser R, Blazar BR
    • Journal Title

      Blood

      Volume: 134 Pages: 1670-1682

    • DOI

      10.1182/blood.2019001950

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] MITOL prevents ER stress-induced apoptosis by IRE1α ubiquitylation at ER-mitochondria contact sites.2019

    • Author(s)
      Takeda, K., Nagashima, S., Shiiba, I., Uda, A., Tokuyama, T., Ito, N., Fukuda, T., Matsushita, N., Ishido, S., Iwawaki, T., Uehara, T., Inatome, R., and Yanagi, S.
    • Journal Title

      The EMBO Journal

      Volume: 38

    • DOI

      10.15252/embj.2018100999

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22498, KAKENHI-PUBLICLY-18H04869, KAKENHI-PROJECT-17H04053, KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-18H02579, KAKENHI-PROJECT-17K08793, KAKENHI-PROJECT-19K16527
  • [Journal Article] Ablation of the Chaperone Protein ERdj5 Results in a Sjogren's Syndrome-Like Phenotype in Mice, Consistent With an Upregulated Unfolded Protein Response in Human Patients2019

    • Author(s)
      Apostolou E, Moustardas P, Iwawaki T, Tzioufas AG, Spyrou G
    • Journal Title

      Front Immunol

      Volume: 10 Pages: 506-506

    • DOI

      10.3389/fimmu.2019.00506

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Molecular Mechanism of Cellular Oxidative Stress Sensing by Keap12019

    • Author(s)
      Suzuki Takafumi、Muramatsu Aki、Saito Ryota、Iso Tatsuro、Shibata Takahiro、Kuwata Keiko、Kawaguchi Shin-ichi、Iwawaki Takao、Adachi Saki、Suda Hiromi、Morita Masanobu、Uchida Koji、Baird Liam、Yamamoto Masayuki
    • Journal Title

      Cell Rep

      Volume: 28 Pages: 746-758

    • DOI

      10.1016/j.celrep.2019.06.047

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07340, KAKENHI-PROJECT-19K07341, KAKENHI-PROJECT-17KK0183, KAKENHI-PUBLICLY-18H04963, KAKENHI-PROJECT-19H05649, KAKENHI-PROJECT-19H00990, KAKENHI-PROJECT-19H01019, KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-18K19417, KAKENHI-ORGANIZER-15H05935
  • [Journal Article] Inhibitory effect of kaempferol on skin fibrosis in systemic sclerosis by the suppression of oxidative stress2019

    • Author(s)
      Sekiguchi A, Motegi SI, Fujiwara C, Yamazaki S, Inoue Y, Uchiyama A, Akai R, Iwawaki T, Ishikawa O
    • Journal Title

      J Dermatol Sci

      Volume: 96 Pages: 8-17

    • DOI

      10.1016/j.jdermsci.2019.08.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-19K21517
  • [Journal Article] IRE1-XBP1 pathway regulates oxidative proinsulin folding in pancreatic β cells2018

    • Author(s)
      Yuichi Tsuchiya, Michiko Saito, Hiroshi Kadokura, Jun-ichi Miyazaki, Fumi Tashiro, Yusuke Imagawa, Takao Iwawaki, Kenji Kohno
    • Journal Title

      The Journal of Cell Biology

      Volume: 217 Pages: 1287-1301

    • DOI

      10.1083/jcb.201707143

    • NAID

      120006457754

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07381, KAKENHI-PROJECT-24228002, KAKENHI-PLANNED-26116006, KAKENHI-PUBLICLY-18H05047, KAKENHI-PROJECT-17H01468, KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-17K15134, KAKENHI-PLANNED-26116005
  • [Journal Article] タンパク質恒常性と糖代謝異常に関わる小胞体ストレス応答の役割2018

    • Author(s)
      岩脇隆夫
    • Journal Title

      金沢医科大学雑誌

      Volume: 43 Pages: 15-22

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] 小胞体ストレスの生体イメージング2018

    • Author(s)
      岩脇隆夫, 赤井良子
    • Journal Title

      THE BONE

      Volume: 32 Pages: 171-177

    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response2018

    • Author(s)
      Chapple RH, Hu T, Tseng YJ, Liu L, Kitano A, Luu V, Hoegenauer KA, Iwawaki T, Li Q, Nakada D
    • Journal Title

      eLife

      Volume: 7

    • DOI

      10.7554/elife.31159

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A2018

    • Author(s)
      Urra H, Henriquez DR, Canovas J, Villarroel-Campos D, Carreras-Sureda A, Pulgar E, Molina E, Hazari YM, Limia CM, Alvarez-Rojas S, Figueroa R, Vidal RL, Rodriguez DA, Rivera CA, Court FA, Couve A, Qi L, Chevet E, Akai R, Iwawaki T, Concha ML, Glavic A, Gonzalez-Billault C, Hetz C
    • Journal Title

      Nature Cell Biology

      Volume: 20 Pages: 942-953

    • DOI

      10.1038/s41556-018-0141-0

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-19K21517
  • [Journal Article] Botulinum toxin B suppresses the pressure ulcer formation in cutaneous ischemia-reperfusion injury mouse model: Possible regulation of oxidative and endoplasmic reticulum stress2018

    • Author(s)
      Sekiguchi A, Motegi SI, Uchiyama A, Uehara A, Fujiwara C, Yamazaki S, Perera B, Nakamura H, Ogino S, Yokoyama Y, Akai R, Iwawaki T, Ishikawa O
    • Journal Title

      Journal of Dermatological Science

      Volume: 90 Pages: 144-153

    • DOI

      10.1016/j.jdermsci.2018.01.006

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366, KAKENHI-PROJECT-19K21517
  • [Journal Article] Activation of Host IRE1α-Dependent Signaling Axis Contributes the Intracellular Parasitism of Brucella melitensis2018

    • Author(s)
      Pandey A, Lin F, Cabello AL, da Costa LF, Feng X, Feng HQ, Zhang MZ, Iwawaki T, Rice-Ficht A, Ficht TA, de Figueiredo P, Qin QM
    • Journal Title

      Frontiers in Cellular and Infection Microbiology

      Volume: 8 Pages: 103-103

    • DOI

      10.3389/fcimb.2018.00103

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Stabilization of cytokine mRNAs in iNKT cells requires the serine-threonine?kinase IRE1alpha2018

    • Author(s)
      Govindarajan S, Gaublomme D, Van der Cruyssen R, Verheugen E, Van Gassen S, Saeys Y, Tavernier S, Iwawaki T, Bloch Y, Savvides SN, Lambrecht BN, Janssens S, Elewaut D, Drennan MB
    • Journal Title

      Nature Communications

      Volume: 9 Pages: 5340-5340

    • DOI

      10.1038/s41467-018-07758-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Journal Article] Correlation between attenuation of protein disulfide isomerase activity through S-mercuration and neurotoxicity induced by methylmercury2015

    • Author(s)
      Makino K, Okuda K, Sugino E, Nishiya T, Toyama T, Iwawaki T, Fujimura M, Kumagai Y, Uehara T.
    • Journal Title

      Neurotoxicity Research

      Volume: 27 Pages: 99-105

    • DOI

      10.1007/s12640-014-9494-8

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-12J03394, KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25670029, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-26460068
  • [Journal Article] Protection afforded by pre- or post-treatment with 4-phenylbutyrate against liver injury induced by acetaminophen overdose in mice.2014

    • Author(s)
      Daisuke Shimizua, Yoichi Ishitsuka, Keishi Miyata, Yoshiro Tomishima, Yuki Kondo, Mitsuru Irikura, Takao Iwawaki, Yuichi Oike, Tetsumi Irie
    • Journal Title

      Pharmacol Res.

      Volume: 87 Pages: 26-41

    • DOI

      10.1016/j.phrs.2014.06.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-25461114, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
  • [Journal Article] Evaluating experimental cerebral malaria using oxidative stress indicator OKD48 mice2014

    • Author(s)
      Imai T, Iwawaki T, Akai R, Suzue K, Hirai M, Taniguchi T, Okada H, Hisaeda H.
    • Journal Title

      Int J Parasitol

      Volume: 44 Pages: 681-5

    • DOI

      10.1016/j.ijpara.2014.06.002

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-24112705, KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-24590501, KAKENHI-PROJECT-25670226, KAKENHI-PROJECT-26860276, KAKENHI-PROJECT-26870094
  • [Journal Article] Temporal activation of Nrf2 in the penumbra and Nrf2 activator-mediated neuroprotection in ischemia-reperfusion injury.2014

    • Author(s)
      Toshinori Takagi, Akira Kitashoji, Takao Iwawaki, Kazuhiro Tsuruma, Masamitsu Shimazawa, Shinichi Yoshimura, Toru Iwama, Hideaki Hara
    • Journal Title

      Free Radic Biol Med

      Volume: 72 Pages: 124-133

    • DOI

      10.1016/j.freeradbiomed.2014.04.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-25861266
  • [Journal Article] The co-chaperone and reductase ERdj5 facilitates rod opsin biogenesis and quality control2014

    • Author(s)
      Dimitra Athanasiou, Dalila Bevilacqua, Monica Aguila, Caroline McCulley, Naheed Kanuga, Takao Iwawaki, J. Paul Chapple, Michael E. Cheetham
    • Journal Title

      Hum. Mol. Genet.

      Volume: 23 Pages: 6594-6606

    • DOI

      10.1093/hmg/ddu385

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] A role for regulated IRE-1 dependent decay in curtailing immunoglobulin secretion from plasma cells2014

    • Author(s)
      Sandrine Benhamron, Takao Iwawaki, Jae-Seon So, Ann-Hwee Lee, Boaz Tirosh
    • Journal Title

      Eur. J. Immunol.

      Volume: 44 Pages: 867-876

    • DOI

      10.1002/eji.201343953

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] Inositol-requiring enzyme 1-α regulates CD8α+ dendritic cell function via regulated mRNA decay2014

    • Author(s)
      Fabiola Osorio, Simon Tavernier, Eik Hoffmann, Yvan Saeys, Liesbet Martens, Jessica Vetters, Iris Delrue, Riet De Rycke, Eef Parthoens, Philippe Poulliot, Takao Iwawaki, Sophie Janssens, Bart N. Lambrecht
    • Journal Title

      Nat. Immunol.

      Volume: 15 Pages: 248-257

    • DOI

      10.1038/ni.2808

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] Comparative analysis of ER stress response into HIV protease inhibitors : Lopinavir but not darunavir induces potent ER stress responsevia ROS/JNK pathway2013

    • Author(s)
      Taura M, Kariya R, Kudo E, Goto H, Iwawaki T, Amano M, Suico MA, Kai H, Mitsuya H, Okada S.
    • Journal Title

      Free Radic. Biol. Med.

      Volume: 65 Pages: 778-788

    • DOI

      10.1016/j.freeradbiomed.2013.08.161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J08328, KAKENHI-PROJECT-23390265, KAKENHI-PROJECT-24390049
  • [Journal Article] Membrane lipid saturation activates IRE1α without inducing clustering.2013

    • Author(s)
      Yuto Kitai, Hiroyuki Ariyama, Nozomu Kono, Daisuke Oikawa, Takao Iwawaki, Hiroyuki Arai
    • Journal Title

      Genes Cells.

      Volume: 18 Pages: 798-809

    • DOI

      10.1111/gtc.12074

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24113702, KAKENHI-PROJECT-25460060
  • [Journal Article] Paneth cells as a site of origin for intestinal inflammation2013

    • Author(s)
      Adolph,T.E.,Tomczak,M.F.,Niederreiter,L.,Ko,H.J.,Bock,J.,Martinez-Naves,E.,Glickman,J.N.,Tschurtschenthaler,M.,Hartwig,J.,Hosomi,S.,Flak,M.B.,Cusick,J.L.,Kohno,K.,Iwawaki,T.,Billmann-Born,S.,Raine,T.,Bharti,R.,Lucius,R.,Kweon,M.N.,Marciniak,S.J.,Choi,A.,Hagen,S.J.,Schreiber,S.,Rosenstiel,P.,Kaser,A.,Blumberg,RS.
    • Journal Title

      Nature

      Volume: 503 Pages: 272-276

    • DOI

      10.1038/nature12599

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24228002, KAKENHI-PROJECT-24390049
  • [Journal Article] 小胞体ストレスシグナルの感知・生体防御機構2013

    • Author(s)
      岩脇隆夫
    • Journal Title

      細胞

      Volume: 45 Pages: 168-171

    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] 小胞体ストレスシグナルの感知・生体防御機構2013

    • Author(s)
      岩脇 隆夫
    • Journal Title

      細胞

      Volume: 45 Pages: 168-171

    • Data Source
      KAKENHI-PUBLICLY-24113702
  • [Journal Article] 生きているマウスで酸化ストレスを見えるように2013

    • Author(s)
      及川大輔、岩脇隆夫
    • Journal Title

      化学と生物

      Volume: 51 Pages: 361-363

    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] CHOP is a critical regulator of acetaminophen-induced hepatotoxicity2013

    • Author(s)
      Dotan Uzi, Liran Barda, Viviana Scaiewicz, Maya Mills, Tobias Mueller, Agueda Gonzalez-Rodriguez, Angela M. Valverde, Takao Iwawaki, Yaakov Nahmias, Ramnik J. Xavier, Raymond T. Chung, Boaz Tirosh, Oren Shibolet
    • Journal Title

      J. Hepatol.

      Volume: 59 Pages: 495-503

    • DOI

      10.1016/j.jhep.2013.04.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells2013

    • Author(s)
      Niederreiter, L., Fritz, T. M. J., Adolph, T.E., Krismer, A. M., Offner, F. A., Tschurtschenthaler, M., Flak, M. B., Hosomi, S., Tomczak, M. F., Kaneider, N. C., Sarcevic, E., Kempster, S. L., Raine, T., Esser, D., Rosenstiel, P., Kohno, K., Iwawaki, T., Tilg, H., Blumberg, R. S., and Kaser, A.
    • Journal Title

      J. Exp. Med.

      Volume: 210(10) Pages: 2041-2056

    • DOI

      10.1084/jem.20122341

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24228002, KAKENHI-PROJECT-24390049
  • [Journal Article] Identification of the redox partners of ERdj5 /JPDI, a PDI family member, from an animal tissue2013

    • Author(s)
      Kadokura, H., Saito, M., Tsuru, A., Hosoda, A., Iwawaki, T., Inaba, K., & Kohno, K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 440 Pages: 245-250

    • DOI

      10.1016/j.bbrc.2013.09.063

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500496, KAKENHI-PUBLICLY-24113702, KAKENHI-PROJECT-24228002, KAKENHI-PROJECT-24580141
  • [Journal Article] Microsomal Triglyceride Transfer Protein Inhibition Induces Endoplasmic Reticulum Stress and Increases Gene Transcription via Ire1α/cJun to Enhance Plasma ALT/AST2013

    • Author(s)
      Josekutty, J., Iqbal, J., Iwawaki, T., Kohno, K., and Hussain, M.
    • Journal Title

      J. Biol. Chem.

      Volume: 288(20) Pages: 14372-14383

    • DOI

      10.1074/jbc.m113.459602

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24228002, KAKENHI-PROJECT-24390049
  • [Journal Article] The role of the unfolded protein response in diabetes mellitus2013

    • Author(s)
      Takao Iwawaki, Daisuke Oikawa
    • Journal Title

      Semin. Immunopathol.

      Volume: 35 Pages: 333-350

    • DOI

      10.1007/s00281-013-0369-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] Positive contribution of IRE1α-XBP1 pathway to the expression of placental cathepsins2013

    • Author(s)
      Daisuke Oikawa, Takao Iwawaki
    • Journal Title

      Biochem. Biophys. Res. Commun.

      Volume: 433 Pages: 426-431

    • DOI

      10.1016/j.bbrc.2013.02.119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] 小胞体ストレスの可視化2012

    • Author(s)
      岩脇 隆夫
    • Journal Title

      生体の科学

      Volume: 65 Pages: 388-389

    • Data Source
      KAKENHI-PUBLICLY-24113702
  • [Journal Article] 小胞体ストレスの可視化2012

    • Author(s)
      岩脇隆夫
    • Journal Title

      生体の科学

      Volume: 65 Pages: 388-389

    • Data Source
      KAKENHI-PROJECT-24390049
  • [Journal Article] Function of yeast and amphioxus tRNA ligase in IRE1alpha-dependent XBP1 mRNA splicing2011

    • Author(s)
      Takao Iwawaki
    • Journal Title

      Biochem.Biophys.Res.Commun.

      Volume: 413 Pages: 527-531

    • DOI

      10.1016/j.bbrc.2011.08.129

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Journal Article] Positive contribution of the IRE1alpha-XBP1 pathway to placental expression of CEA family genes.2010

    • Author(s)
      Daisuke Oikawa, Ryoko Akai, Takao Iwawaki
    • Journal Title

      FEBS Lett. vol.584

      Pages: 1066-1070

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] Positive contribution of Erdj5/JPDI to endoplasmic reticulum protein quality control in the salivary gland.2010

    • Author(s)
      Akira Hosoda, Mio Tokuda, Ryoko Akai, Kenji Kohno, Takao Iwawaki
    • Journal Title

      Biochem. J. vol.425

      Pages: 117-125

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] IRE1alpha disruption causes histological abnormality of exocrine tissues, increase of blood glucose level, and decrease of serum immunoglobulin level.2010

    • Author(s)
      Takao Iwawaki
    • Journal Title

      PLoS ONE

      Volume: 5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] The endoplasmic reticulum stress-CHOP pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques.2010

    • Author(s)
      Hirato Tsukano, Tomomi Gotoh, Motoyoshi Endo, Miyata Keishi, Hirokazu Tazume, Tsuyoshi Kadomatsu, Masato Yano, Takao Iwawaki, Kenji Kohno, Kimi Araki, Hiroshi Mizuta, Yuichi Oike
    • Journal Title

      Arterioscler. Thromb. Vasc.Biol. vol.30

      Pages: 1925-1932

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] IRE1alpha disruption causes histological abnormality of exocrine tissues, increase of blood glucose level, and decrease of serum immunoglobulin level.2010

    • Author(s)
      Takao Iwawaki, Ryoko Akai, Kenji Kohno
    • Journal Title

      PLoS ONE vol.5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] Identication of a consensus element recognized and cleaved by IRE1alpha.2010

    • Author(s)
      Daisuke Oikawa, Mio Tokuda, Akira Hosoda, Takao Iwawaki
    • Journal Title

      Nucleic Acid Res. vol.38

      Pages: 6265-6273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability.2009

    • Author(s)
      Takao Iwawaki, Ryoko Akai, Shinya Yamanaka, Kenji Kohno
    • Journal Title

      Proc.Natl.Acad.Sci.USA vol.106

      Pages: 16657-16662

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Journal Article] Function of IRE1 Alpha in the Placenta is Essential for Placental Development and Embryonic Viability2009

    • Author(s)
      Takao Iwawaki
    • Journal Title

      Proc.Natl.Acad.Sci.USA 106

      Pages: 16657-16662

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Patent] 炎症レポーターシステム2014

    • Inventor(s)
      岩脇隆夫、及川大輔、石川智夫、山村研一
    • Industrial Property Rights Holder
      群馬大学、熊本大学、株式会社トランスジェニック
    • Industrial Property Rights Type
      特許
    • Filing Date
      2014-07-31
    • Overseas
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Patent] 酸化ストレスインジケーター発現用核酸構築物とその使用2012

    • Inventor(s)
      岩脇隆夫, 及川大輔
    • Industrial Property Rights Holder
      独立行政法人理化学研究所
    • Filing Date
      2012-01-20
    • Overseas
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] ストレス可視化モデルマウスの開発と疲労研究への応用2020

    • Author(s)
      岩脇隆夫、赤井良子
    • Organizer
      第16回日本疲労学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] IRE1α Is Essential for Podocyte Proteostasis and Mitochondrial Health2020

    • Author(s)
      Jose R. Navarro-Betancourt, Joan Papillon, Julie Guillemette, Takao Iwawaki, Andrey V. Cybulsky
    • Organizer
      KIDNEY WEEK 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] Role of IRE1α in Podocyte Proteostasis2019

    • Author(s)
      Jose R Navarro-Betancourt, Joan Papillon, Julie Guillemette, Takao Iwawaki, Andrey V Cybulsky
    • Organizer
      KIDNEY WEEK 2019
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] Comparison between endoscopic and histopathological findings in patients with ulcerative colitis2019

    • Author(s)
      Tetsuo Nakayama, Shiko Kuribayashi, Junko Hirato, Takao Iwawaki, Ko Nakata, Hirohito Tanaka, Taku Tomizawa, Hiroko Hosaka, Yasuyuki Shimoyama, Osamu Kawamura, Motoyasu Kusano, Toshio Uraoka
    • Organizer
      Digestive Disease Week 2019
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 睡眠不足モデルマウスにおける細胞ストレス応答と炎症反応の生体イメージング2019

    • Author(s)
      赤井良子、岩脇隆夫
    • Organizer
      第66回日本実験動物学会
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 小胞体ストレス応答分子により制御される過食行動の分子メカニズム2019

    • Author(s)
      岩脇隆夫、赤井良子
    • Organizer
      第14回臨床ストレス応答学会大会
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] ATF4の翻訳活性化機構を利用した統合ストレス可視化モデルマウスの開発2018

    • Author(s)
      赤井良子, 岩脇隆夫
    • Organizer
      住商ファーマインターナショナル株式会社in vivoイメージングフォーラム2018
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 細菌によって利用される宿主細胞の生体防御反応~小胞体ストレス応答~2018

    • Author(s)
      岩脇隆夫
    • Organizer
      第55回日本細菌学会中部支部学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 細胞ストレスおよび炎症可視化モデルマウスの開発とその性能2018

    • Author(s)
      岩脇隆夫
    • Organizer
      第342回熊本大学・発生研セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] ATF4の翻訳活性化機構を利用した統合ストレス可視化モデルマウスの開発と疲労研究への応用2018

    • Author(s)
      岩脇隆夫, 赤井良子
    • Organizer
      第14回日本疲労学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 細胞ストレスおよび炎症可視化モデルマウスの開発とその性能2018

    • Author(s)
      岩脇隆夫
    • Organizer
      第16回京都薬科大学・実験動物セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 『見えない』を『見える』にするマウス2018

    • Author(s)
      岩脇隆夫
    • Organizer
      第20回KMU研究推進セミナー
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] ATF4の翻訳活性化機構を利用した統合ストレス可視化モデルマウスの開発2018

    • Author(s)
      赤井良子, 岩脇隆夫
    • Organizer
      第65回日本実験動物学会
    • Data Source
      KAKENHI-PROJECT-18H02366
  • [Presentation] 異常行動およびエイジングにまで拡がる小胞体ストレス研究の新展開2017

    • Author(s)
      岩脇隆夫
    • Organizer
      東京大学大学院薬学系研究科遺伝学教室主催研究集会2017
    • Place of Presentation
      和光純薬湯河原研修所(静岡県熱海市)
    • Year and Date
      2017-03-12
    • Data Source
      KAKENHI-PROJECT-15K15038
  • [Presentation] 酸化ストレス可視化マウスを用いた脳マラリアの新しい評価法2014

    • Author(s)
      今井孝、岩脇隆夫、赤井良子、鈴江一友、平井誠、谷口委代、岡田紘子、久枝一
    • Organizer
      第83回日本寄生虫学会大会
    • Place of Presentation
      愛媛大学
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] The role of ER stress responses in the control of blood glucose and the biosynthesis of insulin2014

    • Author(s)
      Ryoko Akai, Takao Iwawaki
    • Organizer
      7th APOCB Congress and ASCB Workshops
    • Place of Presentation
      Biopolis(シンガポール)
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] Positive contribution of IRE1α-XBP1 pathway to the expression of placental cathepsins2014

    • Author(s)
      Takao Iwawaki, Daisuke Oikawa
    • Organizer
      7th APOCB Congress and ASCB Workshops
    • Place of Presentation
      Biopolis(シンガポール)
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 胎盤でのCathepsin遺伝子発現制御におけるIRE1αおよびXBP1の役割2013

    • Author(s)
      岩脇隆夫、及川大輔
    • Organizer
      第60回北関東医学会総会
    • Place of Presentation
      群馬大学
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] Fatty acid flux regulates IRE1α activity to control the NLRP3 inflammasome in myeloid cells2013

    • Author(s)
      Megan Robblee, Jess P. Abate, Alex Samocha, Takao Iwawaki, Suneil K. Koliwad
    • Organizer
      The 2013 Meeting on Metabolic Signaling & Disease
    • Place of Presentation
      Cold Spring Harbor(米国)
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] Intrinsically disordered regions in handling of misfolded/unfolded proteins in the ER2013

    • Author(s)
      Takao Iwawaki
    • Organizer
      The 2nd ISIDP International Symposium
    • Place of Presentation
      RIKEN, Yokohama
    • Year and Date
      2013-01-23
    • Data Source
      KAKENHI-PUBLICLY-24113702
  • [Presentation] 細胞ストレス可視化モデルマウスの開発とその性能2013

    • Author(s)
      岩脇隆夫
    • Organizer
      第86回日本生化学会バイオインダストリーセミナー
    • Place of Presentation
      パシフィコ横浜
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 細胞内異常タンパク質代謝における天然変性領域の役割2012

    • Author(s)
      岩脇隆夫
    • Organizer
      新学術領域研究「天然変性タンパク質の分子認識機構と機能発現」第2回公開シンポジウム
    • Place of Presentation
      千里ラィフサイェンスセンター(招待講演)
    • Year and Date
      2012-01-25
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] 小胞体ストレスを『より簡便』に検出する方法2012

    • Author(s)
      岩脇隆夫
    • Organizer
      日本薬学会第132年会
    • Place of Presentation
      北海道大学(招待講演)
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] 細胞ストレス可視化モデルマウスの開発とその性能2012

    • Author(s)
      岩脇隆夫
    • Organizer
      細胞センサーの分子機構・相互作用・ネットワーク研究会
    • Place of Presentation
      生理学研究所
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 酸化ストレス可視化モデルマウスの開発2012

    • Author(s)
      岩脇隆夫
    • Organizer
      第8回日本疲労学会総会・学術集会
    • Place of Presentation
      国立スポーツ科学センター
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] IRE1αとIRE1βによる小胞体ストレス感知機構の違い2012

    • Author(s)
      岩脇 隆夫
    • Organizer
      第7回小胞体ストレス研究会
    • Place of Presentation
      広島大学
    • Year and Date
      2012-11-09
    • Data Source
      KAKENHI-PUBLICLY-24113702
  • [Presentation] 胎盤における小胞体ストレス応答分子の機能2012

    • Author(s)
      岩脇隆夫
    • Organizer
      第4回群馬分子医学研究会
    • Place of Presentation
      群馬大学
    • Year and Date
      2012-10-20
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 動物個体における小胞体ストレスと酸化ストレスのイメージング技術の開発2011

    • Author(s)
      岩脇隆夫
    • Organizer
      第10回国際バイオEXPO
    • Place of Presentation
      東京ビッグサイト
    • Year and Date
      2011-06-30
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] Screening for XBP1 splicing-associated RNA ligase2011

    • Author(s)
      岩脇隆夫
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] Transgenic mouse models for monitoring cellular stress2011

    • Author(s)
      Iwawaki Takao
    • Organizer
      奈良先端未来開拓コロキウム"Protein and Organelle Dynamics under Cellular Stress Conditions"
    • Place of Presentation
      奈良先端科学技術大学院大学(招待講演)
    • Year and Date
      2011-05-31
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] 酸化ストレス可視化モデルマウスの開発2011

    • Author(s)
      岩脇隆夫
    • Organizer
      第6回IVISユーザー会
    • Place of Presentation
      パシフィコ横浜(招待講演)
    • Year and Date
      2011-11-04
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] XBP1のスプライシングに関わるRNAリガーゼのスクリーニング2011

    • Author(s)
      岩脇隆夫
    • Organizer
      第63回日本細胞生物学会
    • Place of Presentation
      北海道大学
    • Year and Date
      2011-06-27
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] マウス個体における酸化ストレスイメージングシステムの開発2011

    • Author(s)
      岩脇隆夫
    • Organizer
      第6回臨床ストレス応答学会
    • Place of Presentation
      名古屋大学医学部
    • Year and Date
      2011-11-05
    • Data Source
      KAKENHI-PUBLICLY-22113524
  • [Presentation] 膵臓β細胞でのインスリン産生におけるIRE1とATF6の役割2010

    • Author(s)
      藤岡洋美、土屋雄一、斉藤美知子、岩脇隆夫、森和俊、河野憲二
    • Organizer
      第33回日本分子生物学会・第83回日本生化学会合同年会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] The role of ER stress responses in the control of blood glucose levels and the biosynthesis of insulin2010

    • Author(s)
      Takao Iwawaki
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      Nara
    • Year and Date
      2010-09-13
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] The role of ER stress responses in the control of blood glucose levels and the biosynthesis of insulin2010

    • Author(s)
      Takao Iwawaki, Akira Hosoda, Ryoko Akai, Mio Tokuda
    • Organizer
      The 3rd International Symposium on Protein Community
    • Place of Presentation
      in Nara
    • Year and Date
      2010-09-13
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 血糖値調節およびインスリン生合成における小胞体ストレス応答の役割2010

    • Author(s)
      岩脇隆夫
    • Organizer
      第5回臨床ストレス応答学会
    • Place of Presentation
      徳島
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 血糖値調節およびインスリン生合成における小胞体ストレス応答の役割2010

    • Author(s)
      岩脇隆夫、細田章、赤井良子、徳田美緒
    • Organizer
      第33回日本分子生物学会・第83回日本生化学会合同年会
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 血糖値調節およびインスリン生合成における小胞体ストレス応答の役割2010

    • Author(s)
      岩脇隆夫、細田章、赤井良子、徳田美緒
    • Organizer
      第5回臨床ストレス応答学会
    • Place of Presentation
      徳島大
    • Year and Date
      2010-11-19
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 胎盤形成における小胞体ストレスセンサーとビタミンEの役割2009

    • Author(s)
      岩脇隆夫
    • Organizer
      エーザイ株式会社第12回Vitamin E Update Forum
    • Place of Presentation
      如水会館、東京
    • Year and Date
      2009-08-31
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Contribution of IRE1 signaling to placental angiogenesis and functuion for embryogenesis2009

    • Author(s)
      岩脇隆夫
    • Organizer
      The 4th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      Sapporo
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Genome-wide screening method for the cleavage target of IRE1alpha2009

    • Author(s)
      Daisuke Oikawa, Mio Tokuda, Akira Hosoda, Takao Iwawaki
    • Organizer
      The 32nd Annual Meeting of the Molecular Biology Society of Japan
    • Place of Presentation
      in Yokohama
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Positive contribution of ERdj5/JPDI to endoplasmic reticulum protein quality control in the salivary gland2009

    • Author(s)
      Akira Hosoda, Mio Tokuda, Ryoko Akai, Kenji Kohno, Takao Iwawaki
    • Organizer
      The 4th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      in Sapporo
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Phenotype analysis of IRE1 alpha conditional knockout mice2009

    • Author(s)
      Ryoko Akai, Kenji Kohno, Takao Iwawaki
    • Organizer
      The 4th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      in Sapporo
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 胎盤形成における小胞体ストレスセンサーとビタミンEの役割2009

    • Author(s)
      岩脇隆夫
    • Organizer
      エーザイ株式会社 第12回 Vitamin E Update Forum
    • Place of Presentation
      東京
    • Year and Date
      2009-08-31
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] PSG遺伝子群の胎盤発現に対するIRE1a-XBP1経路の貢献2009

    • Author(s)
      及川大輔、赤井良子、岩脇隆夫
    • Organizer
      第61回日本細胞生物学会
    • Place of Presentation
      名古屋
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Positive contribution of ERdj5/JPDI to endoplasmic reticulum protein quality control in the salivary gland2009

    • Author(s)
      Akira Hosoda, Mio Tokuda, Ryoko Akai, Kenji Kohno, Takao Iwawaki
    • Organizer
      The 32nd Annual Meeting of the Molecular Biology Society of Japan
    • Place of Presentation
      in Yokohama
    • Year and Date
      2009-12-12
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Contribution of IRE1alpha-XBP1 pathway to the placental expression of PSG genes2009

    • Author(s)
      Daisuke Oikawa, Ryoko Akai, Takao Iwawaki
    • Organizer
      The 4th International Congress on Stress Responses in Biology and Medicine, Poster Presentation
    • Place of Presentation
      in Sapporo
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] Contribution of IRE1 signaling to placental angiogenesis and function for embryogenesis2009

    • Author(s)
      Takao Iwawaki, Ryoko Akai, Shinya Yamanaka, Kenji Kohno
    • Organizer
      The 4th International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      in Sapporo
    • Year and Date
      2009-10-08
    • Data Source
      KAKENHI-PROJECT-21790218
  • [Presentation] 群馬大学で名付けられた遺伝子、IRE1

    • Author(s)
      岩脇隆夫
    • Organizer
      第61回北関東医学会総会
    • Place of Presentation
      群馬大(群馬県前橋市)
    • Year and Date
      2014-09-25 – 2014-09-26
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 細胞ストレス可視化モデルマウスの開発とその性能

    • Author(s)
      岩脇隆夫
    • Organizer
      岡山大&理研ジョイントシンポジウム「最先端計測技術のトレンド2013」
    • Place of Presentation
      岡山大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 動物個体レベルでみる小胞体ストレス応答分子IRE1αの役割

    • Author(s)
      岩脇隆夫
    • Organizer
      第122回東京大学生命環境科学セミナー
    • Place of Presentation
      東京大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 小胞体ストレス応答不全による糖尿病発症機構の解明

    • Author(s)
      斉藤美知子、土屋雄一、岩脇隆夫、森和俊、宮崎純一、河野憲二
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] Unfolded protein response is differently activated by membrane lipid saturation and unfolded proteins in the endoplasmic reticulum

    • Author(s)
      Nozomu Kono, Yuto Kitai, Hiroyuki Ariyama, Daisuke Oikawa, Takao Iwawaki, Hiroyuki Arai
    • Organizer
      FASEB SRC: Phospholipid Cell Signaling and Metabolism in Inflammation and Cancer
    • Place of Presentation
      Niagara Falls (USA)
    • Year and Date
      2014-06-01 – 2014-06-06
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] メチル水銀誘発性神経細胞死における小胞体ストレスの関与

    • Author(s)
      奥田洸作、牧野堅人、外山喬士、西屋禎、岩脇隆夫、熊谷嘉人、上原孝
    • Organizer
      第123回日本薬理学会近畿部会
    • Place of Presentation
      ウインクあいち
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 細胞ストレス可視化モデルマウスの開発とその性能

    • Author(s)
      岩脇隆夫
    • Organizer
      第5回実験動物センター・テクニカルセミナー
    • Place of Presentation
      東京医科歯科大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 細胞ストレス可視化モデルマウスの開発とその性能

    • Author(s)
      岩脇隆夫
    • Organizer
      第8回医工連携グループミーティング
    • Place of Presentation
      群馬大学
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] インスリン生合成に必要な膵臓ベータ細胞におけるeIF2αキナーゼとホスファターゼのバランス機構

    • Author(s)
      岩脇 隆夫、赤井 良子、細田 章、徳田 美緒
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-25 – 2014-11-27
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] 小胞体ストレスセンサーIRE1αによる細胞質スプライシングに必要なmRNAの構造及び配列の解析

    • Author(s)
      池端悠介、今川佑介、柳谷耕太、田丸良子、金谷重彦、岩脇隆夫、河野憲二
    • Organizer
      第66回日本細胞生物学会
    • Place of Presentation
      東大寺総合文化センター(奈良県奈良市)
    • Year and Date
      2014-06-11 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-24390049
  • [Presentation] インスリン産生細胞における小胞体ストレスセンサーIRE1alphaの生理的役割

    • Author(s)
      土屋雄一、斉藤美知子、岩脇隆夫、宮崎純一、河野憲二
    • Organizer
      第66回日本細胞生物学会
    • Place of Presentation
      東大寺総合文化センター(奈良県奈良市)
    • Year and Date
      2014-06-11 – 2014-06-13
    • Data Source
      KAKENHI-PROJECT-24390049
  • 1.  OIKAWA Daisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 2.  TAKAHASHI Yayoi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  ASAI Chiaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  YOSHINO Mayuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  AKAI Ryoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  SAITO Michiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  IMAGAWA Yusuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  KONO Nozomu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  NISHIYA Tadashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  SUZUKI Takafumi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  MORITA Masanobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  MORITA Hironobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  満屋 裕明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  門倉 広
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 15.  河野 憲二
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 16.  宮田 敬士
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  尾池 雄一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  平井 誠
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  久枝 一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  今井 孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  谷口 委代
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  都留 秋雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  高木 俊範
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  上原 孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 25.  柳 茂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  伊藤 昭博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 27.  福田 敏史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  熊谷 嘉人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 29.  山本 雅之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 30.  望田 啓子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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