SEKI Kenjiro 関健二郎

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Researcher Number	50342803
Other IDs
Affiliation *help	2015 – 2018 : 奥羽大学, 薬学部, 准教授 2013 – 2015 : 奥羽大学, 薬学部, 講師 2007 : 循環器病センター, 研究員 2003 : 独立行政法人理化学研究所, 行動遺伝学技術開発チーム, 研究員 2002 : 理化学研究所, 行動遺伝学技術開発チーム, 研究員
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Neuroscience in general / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator 海馬 / シナプス可塑性 / AMPA-GluR2 / ピロカルピン / 月経随伴性てんかん発作 / マウス / 細胞内トラフィッキング / 精神疾患 / HCNチャネル / 老齢 … More

Research Projects
(3results)
Research Products
(3results)

The role of 17beta-estradiol on pilocarpine-induced epilepsy and the downregulation of hippocampal membrane GluR2 and HCN1 channel protein levels in ovariectomized micePrincipal Investigator
- Principal Investigator
  
  SEKI Kenjiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Ohu University
迷走神経刺激による慢性心不全治療効果の細胞内シグナル伝達機序の解明Principal Investigator
- Principal Investigator
  
  関健二郎
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  National Cardiovascular Center Research Institute
アミロイド前駆体蛋白質APPThr668リン酸化によるシナプス可塑性制御機能解析Principal Investigator
- Principal Investigator
  
  関健二郎
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  The Institute of Physical and Chemical Research

All Journal Article Presentation

[Journal Article] Exendin-4 promotes the membrane trafficking of the AMPA receptor GluR1 subunit and ADAM10 in the mouse neocortex.2014
- Author(s)
  Nobuaki Ohtake, Mieko Saito, Masaaki Eto, Kenjiro Seki
- Journal Title
  
  Regulatory Peptides
  
  Volume : 190-191C Pages : 1-11
- DOI
  10.1016/j.regpep.2014.04.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25430070
[Journal Article] Lipopolysaccharide-induced depressive-like behavior is associated with α1-adrenoceptor dependent downregulation of the membrane GluR1 subunit in the mouse medial prefrontal cortex and ventral tegmental area.2014
- Author(s)
  Miyu Sekio, Kenjiro Seki
- Journal Title
  
  International Journal of Neuropsychopharmacology
  
  Volume : 18(1) Pages : 1-12
- DOI
  10.1093/ijnp/pyu005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25430070
[Presentation] 17β-estradiolによるマウス海馬 GluR2 サブユニットのセリン残基（S880）のリン酸化阻害及び internalization 阻害作用とてんかん重積発作後の生存率上昇効果に関する研究2014
- Author(s)
  関健二郎、大竹伸知、飯塚有紀
- Organizer
  日本薬理学会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-25430070