ARIMURA Takuro 有村卓朗

… Alternative Names

ARIMURA TAKURO 有村卓朗

有村卓朗アリムラタクロウ

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Researcher Number	50342887
Other IDs	https://orcid.org/0000-0002-0929-3140
Affiliation (Current)	2025: 鹿児島大学, 農水産獣医学域獣医学系, 教授
Affiliation (based on the past Project Information) *help	2015: 東京医科歯科大学, 難治疾患研究所, 助教 2012: 東京医科歯科大学, 難治疾患研究所, 准教授 2012: 鹿児島大学, 獣医学部, 准教授 2007 – 2009: Tokyo Medical and Dental University, 難治疾患研究所, 助教 2006: 東京医科歯科大学, 難治疾患研究所, 助手
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Human genetics Except Principal Investigator Circulatory organs internal medicine
Keywords	Principal Investigator 特発性心筋症 / テストステロン / 拡張型心筋症 / 肥大型心筋症 / C / ラミンA / CARP / 遺伝子変異 / 心不全 / ラミンA/C … More / 国際研究者交流（ドイツ） / EHTｓ / ANKRD1 / 細胞ストレス / 心筋Z帯 / Cypher / ZASP / PGM1 / フクチン / ミオシン軽鎖 / リン酸化 / 遺伝子発現 / hHS-M21 … More Except Principal Investigator メダカ / 小型魚類変異体 / タイチン / メダカ変異体 / 拡張不全 / 家族性心筋症 Less

Diastolic dysfunction caused by titin mutation
- Principal Investigator
  
  Makino Shinji
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Keio University
体系的遺伝子変異解析に立脚した心不全病態の包括的解明Principal Investigator
- Principal Investigator
  
  有村卓朗
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human genetics
- Research Institution
  Tokyo Medical and Dental University
Molecular pathogenetic mechanism of idiopathic cardiomyopathyPrincipal Investigator
- Principal Investigator
  
  ARIMURA Takuro
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University
心不全病態形成機構の解明と心筋ミオシン軽鎖リン酸化制御に基づく新規治療法の開発Principal Investigator
- Principal Investigator
  
  有村卓朗
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Tokyo Medical and Dental University

All 2014 2013 2012 2010 2009 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] ET-1 induces myofibrillar disarray and contractile vector in hypertrophic cardiomyopathy-iPS cell-derived cardiomyocytes2014
- Author(s)
  Tanaka A, Yuasa S, Mearini G, Egashira T, Seki T, Kodaira M, Kusumoto D, Kuroda Y, Okata S, Suzuki T, Arimura T, Makino S, Kimura K, Kimura A, Furukawa T, Carrier L, Nobe K, Fukuda K
- Journal Title
  
  J Am Heart Assoc
  
  Volume: 3 Issue: 6 Pages: 1-25
- DOI
  10.1161/jaha.114.001263
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293181, KAKENHI-PROJECT-25670126, KAKENHI-PROJECT-25670397, KAKENHI-PROJECT-26670408, KAKENHI-PROJECT-24390201
[Journal Article] Nuclear accumulation of androgen receptor in gender difference of dilated cardiomyopathy due to lamin A/C mutations2013
- Author(s)
  Arimura T
- Journal Title
  
  Cardiovasc. Res.
  
  Volume: In Press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790335
[Journal Article] A novel protein found in the I bands of myofibrils is produced by alternative splicing of the DLST gene.2010
- Author(s)
  Matuda S, Arimura T, Kimura A, Takekura H, Ohta S, Nakano K
- Journal Title
  
  Biochim. Biophys. Acta 1800(1)
  
  Pages: 31-9
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene.2009
- Author(s)
  Moulik M, Vatta M, Witt SH, Arola AM, Murphy RT, McKenna WJ, Boriek A, Oka K, Labeit S, Bowles NE, Arimura T, Kimura A, Towbin JA
- Journal Title
  
  J. Am. Coll. Cardiol 54(4)
  
  Pages: 325-33
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Cardiac ankyrin repeat protein gene (ANKRD1) mutations in hypertrophic cardiomyopathy.2009
- Author(s)
  Arimura T, Bos JM, Sato A, Kubo T, Okamoto H, Nishi H, Harada H, Koga Y, Moulik M, Doi YL, Towbin JA, Ackerman MJ, Kimura A
- Journal Title
  
  J. Am. Coll. Cardiol 54(4)
  
  Pages: 334-42
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Mutational analysis of fukutin gene in dilated cardiomyopathy and hypertrophic cardiomyopathy.2009
- Author(s)
  Arimura T, Hayashi YK, Murakami T, Oya Y, Funabe S, Arikawa EH, Hattori N, Nishino I, Kimura A
- Journal Title
  
  Circ. J. 73(1)
  
  Pages: 158-61
- NAID
  110007007967
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy2009
- Author(s)
  Arimura T, et al.
- Journal Title
  
  Cardiovasc.Res. 83(1)
  
  Pages: 80-88
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Autophagic degradation of nuclear components in mammalian cells.2009
- Author(s)
  Park YE, Hayashi YK, Bonne G, Arimura T, Noguchi S, Nonaka I, Nishino I
- Journal Title
  
  Autophagy 5(6)
  
  Pages: 795-804
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy.2009
- Author(s)
  Arimura T, Inagaki N, Hayashi T, Shichi D, Sato A, Hinohara K, Vatta M, Towbin JA, Chikamori T, Yamashina A, Kimura A
- Journal Title
  
  Cardiovasc. Res. 83(1)
  
  Pages: 80-8
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Megakaryoblastic leukemia factor-1gene in the susceptibility to coronary artery disease.2009
- Author(s)
  Hinohara K, Nakajima T, Yasunami M, Houda S, Sasaoka T, Yamamoto K, Lee BS, Shibata H, Takahashi TY, Arimura T, Sato A, Naruse T, Ban J, Inoko H, Yamada Y, Sawabe M, Park JE, Izumi T, Kimura A
- Journal Title
  
  Hum. Genet. 126(4)
  
  Pages: 539-47
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Novel mechanisms of trafficking defect caused by KCNQ1 mutations found in long QT syndrome.2009
- Author(s)
  Sato A, Arimura T, Makita N, Ishikawa T, Aizawa Y, Ushinohama H, Aizawa Y, Kimura A
- Journal Title
  
  J. Biol. Chem. 284(50)
  
  Pages: 35122-33
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Cardiac ankyrin repeat protein gene(ANKRD1)mutations in hypertrophic cardiomyopathy2009
- Author(s)
  Arimura T, et al.
- Journal Title
  
  J.Am.Coll.Cardiol. 54(4)
  
  Pages: 334-342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Replication of the association between a chromosome 9p21 polymorphism and coronary artery disease in Japanese and Korean populations.2008
- Author(s)
  Hinohara K, Nakajima T, Takahashi M, Hohda S, Sasaoka T, Nakahara K, Chida K, Sawabe M, Arimura T, Sato A, Lee BS, Ban JM, Yasunami M, Park JE, Izumi T, Kimura A
- Journal Title
  
  J. Hum. Genet 53(4)
  
  Pages: 357-9
- NAID
  10021248678
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Mutational analysis of fukutin gene in dilated cardiomyopathy and hypertrophic cardiomyopathy2008
- Author(s)
  Arimura T, et.al.
- Journal Title
  
  Circ. J. 73
  
  Pages: 158-61
- NAID
  110007007967
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy.2007
- Author(s)
  Arimura T, et. al.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 357
  
  Pages: 162-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790492
[Journal Article] Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy2007
- Author(s)
  Muchir A, Pavlidis P, Decostre V, Herron AJ, Arimura T, et. al.
- Journal Title
  
  J. Clin. Invest. 117
  
  Pages: 1282-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790492
[Journal Article] Structural analysis of obscurin gene in hypertrophic cardiomyopathy.2007
- Author(s)
  Arimura T, et. al.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 362
  
  Pages: 281-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790492
[Journal Article] AlphaB-crystallin mutation in dilated cardiomyopathy2006
- Author(s)
  Inagaki N, Hayashi T, Arimura T, et al.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 342(2)
  
  Pages: 379-386
- Data Source
  KAKENHI-PROJECT-18790492
[Journal Article] Cardiac ankyrin repeat protein gene (ANKRDI) mutations in hypertrophic cardiomyopathy
- Author(s)
  Arimura T, et.al.
- Journal Title
  
  J. Am. Coll. Cardiol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Improvement of left ventricular dysfunction and survival prognosis of dilated cardiomyopathy by administration of calcium sensitizer SCH00013 in a mouse model
- Author(s)
  Arimura T, et al.
- Journal Title
  
  J.Am.Coll.Cardiol. (In Press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790520
[Journal Article] Multi-tissular involvement in a family with LMNA and EMD mutations : Role of digenic mechanism?
- Author(s)
  Ben Yaou H, Toutain A, Arimura T, et al.
- Journal Title
  
  Neurology (In press)
- Data Source
  KAKENHI-PROJECT-18790492
[Journal Article] Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy
- Author(s)
  Arimura T, et al.
- Journal Title
  
  Biochem. Biophys. Res. Commun. (In press)
- Data Source
  KAKENHI-PROJECT-18790492
[Journal Article] Activation of MAPK pathways links LMNA mutations to cardiomyopathy in Emery-Dreifuss muscular dystrophy
- Author(s)
  Muchir A, Pavlidis P, Decostre V, Herron AJ, Arimura T, et al.
- Journal Title
  
  J. Clin. Invest. (In press)
- Data Source
  KAKENHI-PROJECT-18790492
[Presentation] Impact of testosterone on progression of dilated cardiomyopathy in a Lmna-mutation knock-in mouse model2013
- Author(s)
  Arimura T
- Organizer
  The 77th Annual Meeting of the Japanese Circulation Society
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790335
[Presentation] Impact of testosterone on progression of dilated cardiomyopathy in a Lmna-mutation knock-in mouse model2012
- Author(s)
  Arimura T
- Organizer
  The 9th Japanese-French Symposium for “Muscular Dystrophy”
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24790335
[Presentation] 肥大型心筋症および拡張型心筋症におけるタイチンA/M帯変異の意義2012
- Author(s)
  有村卓朗
- Organizer
  第57回日本人類遺伝学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790335
[Presentation] Improvement of Left Ventricular Dysfunction and Survival Prognosis of Dilated Cardiomyopathy by Administration of a Novel Calcium Sensitizer in a Mouse Model2009
- Author(s)
  有村卓朗, et al.
- Organizer
  The 12^<th> Cardiovascular Genomics and Atherosclerosis Symposium Satellite Meeting
- Place of Presentation
  韓国・サムソンメディカルセンター
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] テストステロンはラミンA/C遺伝子変異LmnaH222P/H222Pマウスにおける拡張型心筋症を増悪させる2009
- Author(s)
  有村卓朗、木村彰方
- Organizer
  第54回日本人類遺伝学会
- Place of Presentation
  東京
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] Identification of a novel gene for hypertrophic cardiomyopathy2009
- Author(s)
  Arimura T, et.al.
- Organizer
  The 73^<th> Annual Meeting of the Japanese Circulation Society
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] Identification of Novel Disease Genes for Hypertrophic Cardiomyopathy.2009
- Author(s)
  Arimura T
- Organizer
  The 8th Japanese-French Muscular Dystrophy Workshop "Physiopathology to Biotherapy"
- Place of Presentation
  Paris, France
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] Identification of Novel Disease Genes for Hypertrophic Cardiomyopathy2009
- Author(s)
  有村卓朗, et al.
- Organizer
  The 8^<th> Japanese-French Muscular Dystrophy Workshop
- Place of Presentation
  フランス・ピティエサルペトリエール病院
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] テストステロンはラミンA/C遺伝子変異 Lmna^<H222P/H222P>マウスにおける拡張型心筋症を増悪させる2009
- Author(s)
  有村卓朗, et al.
- Organizer
  第54回日本人類遺伝学会
- Place of Presentation
  グランドプリンスホテル高輪
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] Improvement of Left Ventricular Dysfunction and Survival Prognosis of Dilated Cardiomyopathy by Administration of a Novel Calcium Sensitizer in a Mouse Model.2009
- Author(s)
  Arimura T
- Organizer
  The 12th Cardiovascular Genomics and Atherosclerosis Symposium Satellite Meeting
- Place of Presentation
  Seoul, Korea
- Year and Date
  2009-10-17
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] Identification of a novel gene for hypertrophic cardiomyopathy.2009
- Author(s)
  Arimura T, Bos JM, Sato A, Kubo T, Okamoto H, Nishi H, Harada H, Koga Y, Doi YL, Ackerman MJ, Kimura A
- Organizer
  The 73th Annual Meeting of the Japanese Circulation Society
- Place of Presentation
  Osaka, Japan
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] CARPおよびタイチンN2A領域内変異は肥大型心筋症を引き起こす2008
- Author(s)
  有村卓朗、佐藤光希、久保亨、岡本洋、西宏文、原田晴仁、古賀義則、土居義典、木村彰方
- Organizer
  第53回日本人類遺伝学会
- Place of Presentation
  横浜
- Year and Date
  2008-09-28
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] Testicular hormone accelerates the development and progress of dilated cardiomyopathy in an animal model.2008
- Author(s)
  Arimura T, et. al.
- Organizer
  The 72th Annual Meeting of the Japanese Circulation Society
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-18790492
[Presentation] CARPおよびタイチンN2A領域内変異は肥大型心筋症を引き起こす2008
- Author(s)
  有村卓朗, et.al.
- Organizer
  第53回日本人類遺伝学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-09-28
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] 特発性心筋症モデルマウスの作製とその病態解析-ヒトからマウスへ、マウスからヒトへ-2008
- Author(s)
  有村卓朗,et.al.
- Organizer
  第30回心筋生検研究会ミニシンポジウム
- Place of Presentation
  三重大学
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] Identification of Novel Disease Genes for Hereditary Cardiomyopathy.2008
- Author(s)
  Arimura T
- Organizer
  The 11th Cardiovascular Genomics and Atherosclerosis Symposium Satellite Meeting
- Place of Presentation
  Seoul, Korea
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] 特発性心筋症モデルマウスの作製とその病態解析-ヒトからマウスへ、マウスからヒトへ-2008
- Author(s)
  有村卓朗
- Organizer
  第30回心筋生検研究会ミニシンポジウム
- Place of Presentation
  津
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20790520
[Presentation] Identification of Novel Disease Genes for Hereditary Cardiomyopathy2008
- Author(s)
  Arimura T, et.al.
- Organizer
  The 11^<th> Cardiovascular Genomics and Atherosclerosis Symposium Satellite Meeting
- Place of Presentation
  韓国・サムソンメディカルセンター
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-20790520

1. Makino Shinji (20306707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. YAMAGISHI TAKAYUKI (40255500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 木村彰方

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ARIMURA Takuro 有村 卓朗

ARIMURA TAKURO 有村 卓朗

有村 卓朗 アリムラ タクロウ

Research Projects

Research Products

Co-Researchers

Diastolic dysfunction caused by titin mutation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

体系的遺伝子変異解析に立脚した心不全病態の包括的解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular pathogenetic mechanism of idiopathic cardiomyopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

心不全病態形成機構の解明と心筋ミオシン軽鎖リン酸化制御に基づく新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] ET-1 induces myofibrillar disarray and contractile vector in hypertrophic cardiomyopathy-iPS cell-derived cardiomyocytes2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nuclear accumulation of androgen receptor in gender difference of dilated cardiomyopathy due to lamin A/C mutations2013

Author(s)

Journal Title

Data Source

[Journal Article] A novel protein found in the I bands of myofibrils is produced by alternative splicing of the DLST gene.2010

Author(s)

Journal Title

Data Source

[Journal Article] ANKRD1, the gene encoding cardiac ankyrin repeat protein, is a novel dilated cardiomyopathy gene.2009

Author(s)

Journal Title

Data Source

[Journal Article] Cardiac ankyrin repeat protein gene (ANKRD1) mutations in hypertrophic cardiomyopathy.2009

Author(s)

Journal Title

Data Source

[Journal Article] Mutational analysis of fukutin gene in dilated cardiomyopathy and hypertrophic cardiomyopathy.2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy2009

Author(s)

Journal Title

Data Source

[Journal Article] Autophagic degradation of nuclear components in mammalian cells.2009

Author(s)

Journal Title

Data Source

[Journal Article] Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy.2009

Author(s)

Journal Title

Data Source

[Journal Article] Megakaryoblastic leukemia factor-1gene in the susceptibility to coronary artery disease.2009

Author(s)

Journal Title

Data Source

[Journal Article] Novel mechanisms of trafficking defect caused by KCNQ1 mutations found in long QT syndrome.2009

Author(s)

Journal Title

Data Source

[Journal Article] Cardiac ankyrin repeat protein gene(ANKRD1)mutations in hypertrophic cardiomyopathy2009

Author(s)

Journal Title

Data Source

ARIMURA Takuro 有村卓朗

ARIMURA TAKURO 有村卓朗

有村卓朗アリムラタクロウ