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Doi Motomichi  戸井 基道

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戸井 基道  ドイ モトミチ

DOI Motomichi  戸井 基道

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Researcher Number 50344213
Affiliation (Current) 2023: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究グループ付
Affiliation (based on the past Project Information) *help 2021: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究グループ付
2020: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究グループ長
2015: 国立研究開発法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員
2010 – 2014: 独立行政法人産業技術総合研究所, バイオメディカル研究部門, 研究グループ長
2009: National Institute of Advanced Industrial Science and Technology, 脳神経情報研究部門, 研究員
2005 – 2006: 独立行政法人産業技術総合研究所, 脳神経情報研究部門, 研究員
Review Section/Research Field
Principal Investigator
Biological Sciences / Cell biology / Neuroscience in general
Except Principal Investigator
Neurophysiology / General neuroscience / Basic Section 43030:Functional biochemistry-related
Keywords
Principal Investigator
線虫 / 神経回路網 / シナプス形成 / 細胞移動 / 低分子量Gタンパク質 / シナプス / 神経回路 / イメージング / シナプス伝達 / ラミニン … More / シナプス接続 / シナプス小胞放出 / 可視化 / 神経軸索誘導 / 神経軸策伸長 / アクチン / 低分子量Gタンパク質 / 軸索伸長 / 細胞骨格 / 神経軸索伸長 / 細胞極性 … More
Except Principal Investigator
アルツハイマー病 / アミロイドβタンパク質 / シナプス / オリゴマー / トランスジェニックマウス / GFP / 行動解析 / 長期増強 / 凝集体 / 液液相分離 / 線虫C. elegans / 疎水性相互作用 / 核内凝集タンパク質 / 神経細胞 Less
  • Research Projects

    (7 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (6 People)
  •  核内凝集体の除去機構-核内凝集体はウイルスと同一機構によって核外へと運ばれるか?

    • Principal Investigator
      新海 陽一
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Development of new amyloid beta-GFP fusion protein which is a useful tool for the analysis of the synaptic function of amyloid beta monomers and oligomers

    • Principal Investigator
      OCHIISHI TOMOYO
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurophysiology / General neuroscience
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Regulation of cross-talk among small GTPases in cell migration and neuronal axon pathfindingPrincipal Investigator

    • Principal Investigator
      DOI Motomichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  低分子量Gタンパク質群のクロストークによる神経軸索伸張制御Principal Investigator

    • Principal Investigator
      戸井 基道
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Cell biology
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  シナプス接続とシナプス小胞放出の可視化による機能的神経回路網の解明Principal Investigator

    • Principal Investigator
      戸井 基道
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  逆行性シナプス伝達制御因子による機能的神経回路網形成の分子生物学的研究Principal Investigator

    • Principal Investigator
      戸井 基道
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  ターゲット特異的シナプス形成を制御する分子群の探索とカルシウム動態の可視化解析Principal Investigator

    • Principal Investigator
      戸井 基道
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neuroscience in general
    • Research Institution
      National Institute of Advanced Industrial Science and Technology

All 2022 2021 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

  • [Journal Article] The molecular and neural regulation of ultraviolet light phototaxis and its food-associated learning behavioral plasticity in C. elegans2022

    • Author(s)
      Ozawa Kazuki、Shinkai Yoichi、Kako Koichiro、Fukamizu Akiyoshi、Doi Motomichi
    • Journal Title

      Neuroscience Letters

      Volume: 770 Pages: 136384-136384

    • DOI

      10.1016/j.neulet.2021.136384

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06569
  • [Journal Article] Retrogradely transmitted α-synuclein is taken up by the endophilin-independent endocytosis in the C.?elegans neural circuit2021

    • Author(s)
      Wang Xuan、Shinkai Yoichi、Doi Motomichi
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 552 Pages: 176-182

    • DOI

      10.1016/j.bbrc.2021.03.029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K06569
  • [Journal Article] Development of new fusion proteins for visualizing amyloid-β oligomers in vivo2016

    • Author(s)
      Tomoyo Ochiishi, Motomichi Doi, Kazuhiko Yamasaki, Keiko Hirose, Akira Kitamura, Takao Urabe, Nobutaka Hattori, Masataka Kinjo, Tatsuhiko Ebihara & Hideki Shimura
    • Journal Title

      Sci Rep

      Volume: 6 Pages: 22712-22712

    • DOI

      10.1038/srep22712

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26440090, KAKENHI-PROJECT-15K14499, KAKENHI-PROJECT-26640023, KAKENHI-PROJECT-15K14338
  • [Journal Article] The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans.2013

    • Author(s)
      Doi M, Minematsu H, Kubota Y, Nishiwaki K, Miyamoto M.
    • Journal Title

      Development

      Volume: 140 Pages: 3435-3444

    • DOI

      10.1242/dev.089722

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-22111001, KAKENHI-PLANNED-22111005, KAKENHI-PROJECT-24570226
  • [Presentation] Physiological and behavioral roles of intracellular amyloid β oligomer in a novel amyloid β protein transgenic mouse.2015

    • Author(s)
      Tomoyo Ochiishi, Masami Kaku, Kazuhiko Yamasaki, Motomichi Doi, Tatsuhiko Ebihara
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-26640023
  • [Presentation] Development of new animal model of Alzheimer’s disease visualizing the intracellular dynamics of the amyloid-β protein.2015

    • Author(s)
      Tomoyo Ochiishi, Motomichi Doi, Kazuhiko Yamasaki, Akira Kitamura, Takao Urabe, Nobutaka Hattori, Masataka Kinjo, Tatsuhiko Ebihara, Hideki Shimura
    • Organizer
      Neuroscience 2015
    • Place of Presentation
      Chicago, IL, USA
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26640023
  • [Presentation] Development of new animal models of Alzheimer’s disease visualizing intracellular dynamics of the amyloid β protein.2014

    • Author(s)
      Tomoy Ochiishi, Motomichi Doi, Hideki Shimura, Takao Urabe, Nobutaka, Hattori and Tatsuhiko Ebihara
    • Organizer
      International Symposium on Translational Neuroscience and XXXII Annual Conference of Indian Academy of Neuroscience
    • Place of Presentation
      NIMHANS Convention center (Bengaluru, India)
    • Year and Date
      2014-11-01
    • Invited
    • Data Source
      KAKENHI-PROJECT-26640023
  • [Presentation] Molecular and cellular analysis of functional crosstalk among the small GTPases through interaction with a VPS9-domain protein Rin1.2014

    • Author(s)
      戸井基道、塚越紗椰、佐藤優花里、千田俊哉
    • Organizer
      PIM国際シンポジウム2014
    • Place of Presentation
      愛媛大学(愛媛)
    • Year and Date
      2014-09-15
    • Data Source
      KAKENHI-PROJECT-24570226
  • [Presentation] Visualization and functional analysis of intracellular Amyloid β protein in pre and postsynaptic regions2014

    • Author(s)
      Tomoyo Ochiishi, Motomichi Doi, Hideki Shimura, Takao Urabe, Nobutaka Hattori, Tatsuhiko Ebihara
    • Organizer
      第37回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2014-11-27
    • Data Source
      KAKENHI-PROJECT-26640023
  • [Presentation] VPS9ドメインを有するRIN-1タンパク質は線虫の細胞移動や軸索伸長を制御する新規のRacエフェクターである2012

    • Author(s)
      戸井基道、峯松英樹、久保田幸彦、西脇清二、宮本昌明
    • Organizer
      第35回日本分子生物学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24570226
  • [Presentation] 新規のRacエフェクターRIN-1による線虫生体内の神経細胞の移動と軸索伸長制御2011

    • Author(s)
      戸井基道
    • Organizer
      第84回日本生化学会大会
    • Place of Presentation
      京都府京都国際会館
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-22570196
  • [Presentation] Ras-interacting protein RIN-1 is a novel effector for Rac that regulate the neuronal cell migration and axon guidance.2010

    • Author(s)
      戸井基道
    • Organizer
      4th East Asia Worm Meeting
    • Place of Presentation
      東京
    • Year and Date
      2010-07-11
    • Data Source
      KAKENHI-PROJECT-22570196
  • [Presentation] Ras-interacting protein RIN-1 is a novel effector for Rac that regulate the neuronal cell migration and axon guidance.2010

    • Author(s)
      戸井基道
    • Organizer
      BMB2010
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-08
    • Data Source
      KAKENHI-PROJECT-22570196
  • [Presentation] Caenorhabditis elegans Ras-interacting protein 1 homologue RIN-1 is a novel effector protein of CED-10/Rac that regulates neuronal cell and axon growth cone migration2009

    • Author(s)
      戸井基道
    • Organizer
      第32回日本神経科学学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-09-16
    • Data Source
      KAKENHI-PUBLICLY-21115522
  • [Presentation] The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans.

    • Author(s)
      Motomichi Doi, Hideki Minematsu, Yukihiko Kubota, Kiyoji Nishiwaki, Masaaki Miyamoto
    • Organizer
      ASCB2013
    • Place of Presentation
      New Orleans
    • Data Source
      KAKENHI-PROJECT-24570226
  • [Presentation] Molecular and cellular analysis of neuronal circuit formation and function in C. elegans

    • Author(s)
      戸井基道
    • Organizer
      International Symposium on Translational Neuroscience and 32th Annual Conference of Indian Academy of Neuroscience Meeting
    • Place of Presentation
      バンガロール(インド)
    • Year and Date
      2014-11-01 – 2014-11-03
    • Invited
    • Data Source
      KAKENHI-PROJECT-24570226
  • 1.  OCHIISHI TOMOYO (30356729)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 2.  KAKU Masami (30646261)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  EBIHARA Tatsuhiko (00344119)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 4.  新海 陽一 (00758378)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  NISHIWAKI Kiyoji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  北村 朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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