DOI Motomichi 戸井基道

Researcher Number	50344213
Other IDs
Affiliation *help	2018 : 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究グループ長 2016 – 2018 : 筑波大学, 生命環境系, 連携大学院(准教授) 2016 – 2017 : 国立研究開発法人産業技術総合研究所, その他部局等, 研究員 2015 : 国立研究開発法人産業技術総合研究所, バイオメディカル研究部門, 主任研究員 2010 – 2014 : 独立行政法人産業技術総合研究所, バイオメディカル研究部門, 研究グループ長 2009 : National Institute of Advanced Industrial Science and Technology, 脳神経情報研究部門, 研究員 2005 – 2006 : 独立行政法人産業技術総合研究所, 脳神経情報研究部門, 研究員
Review Section/Research Field	Principal Investigator Cell biology / Biological Sciences / Neuroscience in general Except Principal Investigator Neurophysiology / General neuroscience
Keywords	Principal Investigator 線虫 / シナプス形成 / 神経回路網 / 低分子量Gタンパク質 / 細胞移動 / 神経軸策伸長 / ラミニン / 可視化 / 神経軸索伸長 / シナプス小胞放出 … More Except Principal Investigator 行動解析 / アミロイドβタンパク質 / オリゴマー / 長期増強 / シナプス / アルツハイマー病 / トランスジェニックマウス / GFP Less

Development of new amyloid beta-GFP fusion protein which is a useful tool for the analysis of the synaptic function of amyloid beta monomers and oligomers
- Principal Investigator
  
  OCHIISHI TOMOYO
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Regulation of cross-talk among small GTPases in cell migration and neuronal axon pathfindingPrincipal Investigator
- Principal Investigator
  
  DOI Motomichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  National Institute of Advanced Industrial Science and Technology
低分子量Gタンパク質群のクロストークによる神経軸索伸張制御Principal Investigator
- Principal Investigator
  
  戸井基道
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  National Institute of Advanced Industrial Science and Technology
シナプス接続とシナプス小胞放出の可視化による機能的神経回路網の解明Principal Investigator
- Principal Investigator
  
  戸井基道
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Advanced Industrial Science and Technology
逆行性シナプス伝達制御因子による機能的神経回路網形成の分子生物学的研究Principal Investigator
- Principal Investigator
  
  戸井基道
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Advanced Industrial Science and Technology
ターゲット特異的シナプス形成を制御する分子群の探索とカルシウム動態の可視化解析Principal Investigator
- Principal Investigator
  
  戸井基道
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  National Institute of Advanced Industrial Science and Technology

All 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Development of new fusion proteins for visualizing amyloid-β oligomers in vivo2016
- Author(s)
  Tomoyo Ochiishi, Motomichi Doi, Kazuhiko Yamasaki, Keiko Hirose, Akira Kitamura, Takao Urabe, Nobutaka Hattori, Masataka Kinjo, Tatsuhiko Ebihara & Hideki Shimura
- Journal Title
  
  Sci Rep
  
  Volume : 6 Pages : 22712-22712
- DOI
  10.1038/srep22712
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26440090, KAKENHI-PROJECT-15K14499, KAKENHI-PROJECT-26640023, KAKENHI-PROJECT-15K14338
[Journal Article] The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans.2013
- Author(s)
  Doi M, Minematsu H, Kubota Y, Nishiwaki K, Miyamoto M.
- Journal Title
  
  Development
  
  Volume : 140 Pages : 3435-3444
- DOI
  10.1242/dev.089722
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22111001, KAKENHI-PLANNED-22111005, KAKENHI-PROJECT-24570226
[Presentation] Development of new animal model of Alzheimer’s disease visualizing the intracellular dynamics of the amyloid-β protein.2015
- Author(s)
  Tomoyo Ochiishi, Motomichi Doi, Kazuhiko Yamasaki, Akira Kitamura, Takao Urabe, Nobutaka Hattori, Masataka Kinjo, Tatsuhiko Ebihara, Hideki Shimura
- Organizer
  Neuroscience 2015
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640023
[Presentation] Physiological and behavioral roles of intracellular amyloid β oligomer in a novel amyloid β protein transgenic mouse.2015
- Author(s)
  Tomoyo Ochiishi, Masami Kaku, Kazuhiko Yamasaki, Motomichi Doi, Tatsuhiko Ebihara
- Organizer
  第38回日本神経科学大会
- Place of Presentation
  神戸国際会議場（兵庫県）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-26640023
[Presentation] Development of new animal models of Alzheimer’s disease visualizing intracellular dynamics of the amyloid β protein.2014
- Author(s)
  Tomoy Ochiishi, Motomichi Doi, Hideki Shimura, Takao Urabe, Nobutaka, Hattori and Tatsuhiko Ebihara
- Organizer
  International Symposium on Translational Neuroscience and XXXII Annual Conference of Indian Academy of Neuroscience
- Place of Presentation
  NIMHANS Convention center (Bengaluru, India)
- Year and Date
  2014-11-01
- Invited
- Data Source
  KAKENHI-PROJECT-26640023
[Presentation] Visualization and functional analysis of intracellular Amyloid β protein in pre and postsynaptic regions2014
- Author(s)
  Tomoyo Ochiishi, Motomichi Doi, Hideki Shimura, Takao Urabe, Nobutaka Hattori, Tatsuhiko Ebihara
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PROJECT-26640023
[Presentation] Molecular and cellular analysis of functional crosstalk among the small GTPases through interaction with a VPS9-domain protein Rin1.2014
- Author(s)
  戸井基道、塚越紗椰、佐藤優花里、千田俊哉
- Organizer
  PIM国際シンポジウム２０１４
- Place of Presentation
  愛媛大学（愛媛）
- Year and Date
  2014-09-15
- Data Source
  KAKENHI-PROJECT-24570226
[Presentation] VPS9ドメインを有するRIN-1タンパク質は線虫の細胞移動や軸索伸長を制御する新規のRacエフェクターである2012
- Author(s)
  戸井基道、峯松英樹、久保田幸彦、西脇清二、宮本昌明
- Organizer
  第35回日本分子生物学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-24570226
[Presentation] 新規のRacエフェクターRIN-1による線虫生体内の神経細胞の移動と軸索伸長制御2011
- Author(s)
  戸井基道
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  京都府京都国際会館
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22570196
[Presentation] Ras-interacting protein RIN-1 is a novel effector for Rac that regulate the neuronal cell migration and axon guidance.2010
- Author(s)
  戸井基道
- Organizer
  BMB2010
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22570196
[Presentation] Ras-interacting protein RIN-1 is a novel effector for Rac that regulate the neuronal cell migration and axon guidance.2010
- Author(s)
  戸井基道
- Organizer
  4th East Asia Worm Meeting
- Place of Presentation
  東京
- Year and Date
  2010-07-11
- Data Source
  KAKENHI-PROJECT-22570196
[Presentation] Caenorhabditis elegans Ras-interacting protein 1 homologue RIN-1 is a novel effector protein of CED-10/Rac that regulates neuronal cell and axon growth cone migration2009
- Author(s)
  戸井基道
- Organizer
  第32回日本神経科学学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PUBLICLY-21115522
[Presentation] The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans.
- Author(s)
  Motomichi Doi, Hideki Minematsu, Yukihiko Kubota, Kiyoji Nishiwaki, Masaaki Miyamoto
- Organizer
  ASCB2013
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-24570226
[Presentation] Molecular and cellular analysis of neuronal circuit formation and function in C. elegans
- Author(s)
  戸井基道
- Organizer
  International Symposium on Translational Neuroscience and 32th Annual Conference of Indian Academy of Neuroscience Meeting
- Place of Presentation
  バンガロール（インド）
- Year and Date
  2014-11-01 – 2014-11-03
- Invited
- Data Source
  KAKENHI-PROJECT-24570226

1. OCHIISHI TOMOYO (30356729)

# of Collaborated Projects : 1results

# of Collaborated Products : 5results
2. KAKU Masami (30646261)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
3. EBIHARA Tatsuhiko (00344119)

# of Collaborated Projects : 1results

# of Collaborated Products : 5results
4. 北村朗

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
5. 西脇清二

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

DOI Motomichi 戸井 基道

Research Projects

Research Products

Co-Researchers

Development of new amyloid beta-GFP fusion protein which is a useful tool for the analysis of the synaptic function of amyloid beta monomers and oligomers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of cross-talk among small GTPases in cell migration and neuronal axon pathfindingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

低分子量Gタンパク質群のクロストークによる神経軸索伸張制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

シナプス接続とシナプス小胞放出の可視化による機能的神経回路網の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

逆行性シナプス伝達制御因子による機能的神経回路網形成の分子生物学的研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ターゲット特異的シナプス形成を制御する分子群の探索とカルシウム動態の可視化解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Development of new fusion proteins for visualizing amyloid-β oligomers in vivo2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Development of new animal model of Alzheimer’s disease visualizing the intracellular dynamics of the amyloid-β protein.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Physiological and behavioral roles of intracellular amyloid β oligomer in a novel amyloid β protein transgenic mouse.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Development of new animal models of Alzheimer’s disease visualizing intracellular dynamics of the amyloid β protein.2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Visualization and functional analysis of intracellular Amyloid β protein in pre and postsynaptic regions2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Molecular and cellular analysis of functional crosstalk among the small GTPases through interaction with a VPS9-domain protein Rin1.2014

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

DOI Motomichi 戸井基道