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Ito Tsukasa  伊藤 吏

… Alternative Names

ITO Tsukasa  伊藤 吏

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Researcher Number 50344809
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-4237-3564
External Links
Affiliation (Current) 2025: 山形大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 山形大学, 医学部, 教授
2016 – 2023: 山形大学, 医学部, 准教授
2014 – 2016: 山形大学, 医学部, 講師
2014: 山形大学, 医学部, 助教
2013: 山形大学, 医学部, 非常勤講師 … More
2012: 山形大学, 医学部, 助教
2009 – 2010: Yamagata University, 医学部, 助教
2002 – 2006: 山形大学, 医学部, 助手 Less
Review Section/Research Field
Principal Investigator
Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related
Except Principal Investigator
Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related / Surgery related to the biological and sensory functions and related fields / Otorhinolaryngology
Keywords
Principal Investigator
モルモット / 中耳真珠腫 / 真珠腫性中耳炎 / 中耳粘膜再生 / レチノイド / 経外耳道的内視鏡下耳科手術 / 再生医療 / 線毛上皮 / 中耳粘膜 / 内視鏡下耳科手術 … More / 小児難聴 / 他覚的聴力検査 / 聴性定常反応 / 線毛円柱上皮 / 分化誘導 / 再形成性再発 / 遺残性再発 / 低侵襲手術 / 慢性中耳炎 / 間葉系幹細胞 / 真珠製中耳炎 / HMGB1 / 睡眠深度 / 聴性定常反応(ASSR) / 精密聴力検査 / 新生児聴覚スクリーニング / 睡眠 / 受精因子 / 頭頚部癌 / mRNA / 酵素活性 / 頭頸部癌 / Thymidylate Synthase / Orotate Phosphoribosyl Transferase / DihydroPyrimidine Dehydrogenase / 5-FU … More
Except Principal Investigator
内耳 / 感音難聴 / シナプス再生 / ROCK阻害薬 / 再生 / 有毛細胞 / 聴神経 / 難聴 / 再生医学 / 神経 / シナプス / 幹細胞 / 音響暴露 / 内耳再生 / 内耳障害 / RT-PCR / DGK inhibitor / ジアシルグリセロールキナーゼ / EarFlow / 蝸牛シナプス障害 / 内視鏡下耳科手術 / ドラッグデリバリーシステム / 蝸牛シナプス / 側頭骨病理 / 小胞体 / 血管条 / グルココルチコイド / 耳硬化症 / グルココルチコイドレセプター / ヒト側頭骨病理 / 副腎皮質ホルモン / コルチ器 / Cochlear synaptopathy / cochlear synaptopathy / 蝸牛神経 / 内有毛細胞 / Cochlear Synaptopathy / 聴覚再生 / LISW / 蝸牛 / 耳科学 / 内耳3次元器官培養 / 多能性幹細胞 / 再生医療 / 外有毛細胞 / 聴覚 / 幹細胞移植 / cell growth / specific antibody / human malignant tumor cells / diacylglycerol kinase / protein kinase C / diacylglycerol / 扇平上皮癌 / 甲状腺癌 / 扁平上皮癌 / 頭頚部癌 / 細胞増殖 / 特異抗体 / プロテインキナーゼC / 頭頸部悪性腫瘍 / multiple amplitude-modulated tones / amplitude-modulation following response / steady-state response / 他覚的聴力検査 / 他覚的聴力検査装置 / 複合振幅変調音 / 変調周波数追随反応 / 聴性定常反応 / Matrigel / 神経再生 / ヒト皮膚繊維芽細胞 / 顔面神経損傷モデル / ラット / 機能再生 / ヒト皮膚線維芽細胞 / 顔面神経麻痺 / 聴覚医学 Less
  • Research Projects

    (17 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (20 People)
  •  EarFlowを用いた蝸牛シナプス障害に対する新規治療の確立

    • Principal Investigator
      欠畑 誠治
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Yamagata University
  •  Development of a Fundamental Therapeutic Approach for the Treatment of Middle Ear Cholesteatoma Using Technology of Regeneration and Induction of Differentiation of Middle Ear MucosaPrincipal Investigator

    • Principal Investigator
      伊藤 吏
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Yamagata University
  •  聴神経・シナプス再生の細胞内メカニズムの解明

    • Principal Investigator
      天野 彰子
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Yamagata University
  •  難聴治療の挑戦 -内耳における小胞体・リン脂質代謝酵素および再生因子の解析-

    • Principal Investigator
      松井 祐興
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Yamagata University
  •  Development of a minimally invasive technique to regenerate the middle ear mucosa in the treatment of middle ear cholesteatoma.Principal Investigator

    • Principal Investigator
      Ito Tsukasa
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Yamagata University
  •  Development of regenerative therapy targeting synapses between inner hair cells and cochlear nerves

    • Principal Investigator
      Kakehata Seiji
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      Yamagata University
  •  Study for the curative treatment of middle ear cholesteatoma by regeneration of middle ear mucosa using autologous stem cell inductionPrincipal Investigator

    • Principal Investigator
      Ito Tsukasa
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamagata University
  •  Challenge to development of new regenerative therapy targeting synapses between hair cells and auditory nerve fibers

    • Principal Investigator
      Kakehata Seiji
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Yamagata University
  •  永続型耳鳴治療(埋込型岬角電気刺激装置)をめざして

    • Principal Investigator
      WATANABE Tomoo
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamagata University
  •  Multifaceted analysis of inner ear regeneration using Muse cells

    • Principal Investigator
      kakehata seiji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamagata University
  •  Challenges for effective delivery of stem cells to the organ of Corti

    • Principal Investigator
      Kakehata Seiji
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamagata University
  •  Effect of transplanting normal human dermal fibroblasts (NHDF) in the rat facial nerve palsy model

    • Principal Investigator
      KAKEHATA Seiji
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamagata University
  •  Development of Novel Objective Audiometry Based on Auditory Steady State Response and Sleep Stage AnalysisPrincipal Investigator

    • Principal Investigator
      ITO Tsukasa
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamagata University
  •  The research and development of the new objective audiometry technique using an auditory steady-state response (ASSR) in sleeping subjectsPrincipal Investigator

    • Principal Investigator
      ITO Tsukasa
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamagata University
  •  頭頚部癌における5-FU感受性因子の新しい定量法の開発とその有用性に関する検討Principal Investigator

    • Principal Investigator
      伊藤 吏
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamagata University
  •  Immunohistochemical and molecular biological study on expression of diacylglycrol kinase in human origined malignant tumor cells from head and neck

    • Principal Investigator
      KOIKE Shuji
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamagata University School of Medicine
  •  Clinical Application of Auditory Steady-State Response evoked by multiple simultaneous amplitude-modulated stimuli (amplitude-modulation following response : AMFR) for Assessment of hearing in infants and young children

    • Principal Investigator
      WATANABE Tomoo, SUZUKI Yutaka
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Yamagata-uniersity

All 2023 2022 2021 2020 2019 2018 2011 2010 2005 2004 2003 Other

All Journal Article Presentation

  • [Journal Article] 【内視鏡所見カラーアトラス】「外耳道・鼓膜」(特集)2023

    • Author(s)
      松井祐興,伊藤吏
    • Journal Title

      医学書院「耳鼻咽喉科・頭頸部外科」

      Volume: 95(3) Pages: 198-203

    • Data Source
      KAKENHI-PROJECT-21K09649
  • [Journal Article] Consistent removal of hair cells in vestibular end organs by time-dependent transtympanic administration of gentamicin in guinea pigs2021

    • Author(s)
      Chiba Makoto、Ito Tsukasa、Shinkawa Chikako、Koizumi Yutaka、Hull Melinda、Kakehata Seiji
    • Journal Title

      Journal of Neuroscience Methods

      Volume: 351 Pages: 109049-109049

    • DOI

      10.1016/j.jneumeth.2020.109049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16887, KAKENHI-PROJECT-20H03833
  • [Journal Article] Regenerative Effect of a ROCK Inhibitor, Y-27632, on Excitotoxic Trauma in an Organotypic Culture of the Cochlea2020

    • Author(s)
      Koizumi Y, Ito T, Mizutari K, Kakehata S.
    • Journal Title

      Front. Cell. Neurosci.

      Volume: 14 Pages: 572434-572434

    • DOI

      10.3389/fncel.2020.572434

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09335, KAKENHI-PROJECT-20KK0204, KAKENHI-PROJECT-17K19713, KAKENHI-PROJECT-17K16887, KAKENHI-PROJECT-20H03833
  • [Journal Article] Expression and localization of diacylglycerol kinase ζ in guinea pig cochlea and its functional implication under noise-exposure stress conditions2019

    • Author(s)
      Shinkawa C, Ito T, Hozumi Y, Chiba M, Matsui H, Goto K, Kakehata S
    • Journal Title

      Histochem Cell Biol.

      Volume: epub Issue: 6 Pages: 461-474

    • DOI

      10.1007/s00418-019-01781-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05479, KAKENHI-PROJECT-17K08507
  • [Journal Article] 聴力正常者におけるASSRの刺激音圧とパワー・潜時・CSMの関係2010

    • Author(s)
      窪田俊憲, 伊藤 吏, 渡辺知緒, 阿部靖弘, 千葉寛之, 井川信子, 鈴木豊, 青柳優
    • Journal Title

      ASSRを用いた補充現象解析へむけて.Audiology Japan 53

      Pages: 266-273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21791591
  • [Journal Article] Gene expression, cellular localization, and enzymatic activity of diacylglycerol kinase isozymes in rat ovary and placenta.2005

    • Author(s)
      Toya M, Hozumi Y, Ito T, Takeda M, Sakane F, Kanoh H, Saito H, Hiroi M, Kurachi H, Kondo H, Goto K.
    • Journal Title

      Cell Tissue Res. Jun;320(3)

      Pages: 525-533

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591795
  • [Journal Article] Expression and localization of diacylglycerol kinase isozymes and enzymatic features in rat lung.2005

    • Author(s)
      Katagiri Y, Ito T, Saino-Saito S, Hozumi Y, Suwabe A, Otake K, Sata M, Kondo H, Sakane F, Kanoh H, Kubota I, Goto K.
    • Journal Title

      Am J Physiol Lung Cell Mol Physiol. Jun;288(6)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591795
  • [Journal Article] Cloning and characterization of DGKι splice variants in rat brain.2004

    • Author(s)
      Ito T, Hozumi Y, et al.
    • Journal Title

      J Biol Chem. 279(22)

      Pages: 23317-23326

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591795
  • [Journal Article] Cloning and characterization of diacylglycerol kinase iota splice variants in rat brain.2004

    • Author(s)
      Ito T, Hozumi Y, Sakane F, Saino-Saito S, Kanoh H, Aoyagi M, Kondo H, Goto K.
    • Journal Title

      J Biol Chem. May 28;279(22)

      Pages: 23317-23326

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591795
  • [Journal Article] Nuclear localization of diacylglycerol kinase zeta in neurons.2003

    • Author(s)
      Hozumi Y, Ito T, et al.
    • Journal Title

      Eur J Neurosci 18(6)

      Pages: 1448-1457

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591795
  • [Journal Article] Nuclear localization of diacylglycerol kinase zeta in neurons.2003

    • Author(s)
      Hozumi Y, Ito T, Nakano T, Nakagawa T, Aoyagi M, Kondo H, Goto K.
    • Journal Title

      Eur J Neurosci. Sep;18(6)

      Pages: 1448-1457

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591795
  • [Presentation] 外耳道骨腫摘出における電動式骨手術器械「ZAOSONiC」の使用経験2023

    • Author(s)
      松井祐興, 伊藤吏, 後藤崇成, 新川智佳子, 欠畑誠治
    • Organizer
      第32回日本頭頸部外科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-21K09649
  • [Presentation] レチノイドを用いた中耳粘膜再生治療について2022

    • Author(s)
      寺田小百合,伊藤 吏,小泉 優,天野 彰子,新川智佳子,欠畑 誠治
    • Organizer
      第70回日本耳鼻咽喉科学会東北地方部会連合学術講演会
    • Data Source
      KAKENHI-PROJECT-20K09725
  • [Presentation] 耳管および前鼓室・耳管上陥凹病変への進展を伴う後天性真珠腫の検討.2022

    • Author(s)
      松井祐興, 伊藤吏, 二井一則, 窪田俊憲, 古川孝俊, 後藤崇成, 新川智佳子, 杉山元康, 天野彰子, 天野真太郎, 欠畑誠治.
    • Organizer
      第32回日本耳科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-21K09649
  • [Presentation] TEESによるレチノイド局所投与により再生した中耳粘膜の機能評価2022

    • Author(s)
      寺田小百合,伊藤 吏,小泉 優,天野 彰子,新川智佳子,欠畑 誠治
    • Organizer
      第32回日本耳科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-20K09725
  • [Presentation] ヒト内耳におけるグルココルチコイドレセプターとミネラルコルチコイドレセプターの免疫組織学的検討.2022

    • Author(s)
      松井祐興, 伊藤吏, 窪田俊憲, 新川智佳子, 天野彰子, 欠畑誠治.
    • Organizer
      第67回日本聴覚医学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-21K09649
  • [Presentation] 内耳瘻孔症例の検討2022

    • Author(s)
      松井祐興, 伊藤吏.
    • Organizer
      第7回東北耳科研究会
    • Data Source
      KAKENHI-PROJECT-21K09649
  • [Presentation] Surgical evaluation of secondary acquired cholesteatoma2022

    • Author(s)
      Hirooki Matsui, Tsukasa Ito, Toshinori Kubota, Takatoshi Furukawa, Takanari Goto, Chikako Shinkawa, Kazunori Futai, Shintaro Amano, Seiji Kakehata.
    • Organizer
      World Congress on Endoscopic Surgery 4.0, Kyoto, Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09649
  • [Presentation] COVID-19感染予防対策における音の遮蔽と語音聴取に対する影響についての検討2021

    • Author(s)
      松井祐興、伊藤吏、窪田俊憲、新川智佳子、天野彰子、千葉寛之、石山弘将、綿貫敬介、不破大介、欠畑誠治
    • Organizer
      第66回 日本聴覚医学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-21K09649
  • [Presentation] Laser-induced shock waveによるcochlear synaptopathyモデルに対するROCK阻害薬の効果の検討2021

    • Author(s)
      小泉 優, 水足 邦雄, 伊藤 吏, 塩谷 彰浩, 欠畑 誠治
    • Organizer
      第31回日本耳科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-20H03833
  • [Presentation] Cochlear synaptopathy をターゲットとした治療法開発への試み ~当科での内耳基礎研究について~2021

    • Author(s)
      小泉 優 , 伊藤 , 吏 , 窪田俊憲 , 松井祐興 , 新川智佳子 , 寺田小百合 , 天野彰子 , 欠畑誠治
    • Organizer
      第6回耳鳴・難聴研究会
    • Data Source
      KAKENHI-PROJECT-20H03833
  • [Presentation] 実験動物モデルにおける ABR を用いた伝音難聴と感音難聴の鑑別について2021

    • Author(s)
      寺田小百合 , 伊藤 吏 , 新川智佳子 , 小泉 優 , 天野彰子 , 松井祐興 , 窪田俊憲 , 欠畑誠治
    • Organizer
      第1回 ERA・ERP 研究会
    • Data Source
      KAKENHI-PROJECT-20H03833
  • [Presentation] レチノイドを用いた中耳粘膜上皮の創傷治癒効果について2021

    • Author(s)
      寺田 小百合, 伊藤 吏, 小泉 優, 天野 彰子, 新川 智佳子, 欠畑 誠治
    • Organizer
      第31回日本耳科学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-20H03833
  • [Presentation] レチノイドを用いた中耳粘膜上皮の創傷治癒効果について2021

    • Author(s)
      寺田小百合,伊藤 吏,小泉 優,天野 彰子,新川智佳子,欠畑 誠治
    • Organizer
      第 31 回日本耳科学会 総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-20K09725
  • [Presentation] ROCK inhibitor Y-27632 accelerates auditory nerve fiber growth and synapse formation after excitotoxic trauma in organotypic culture of cochlea2019

    • Author(s)
      Yutaka Koizumi, Tsukasa Ito, Seiji Kakehata
    • Organizer
      Association for Research in Otolaryngology 42nd Annual MidWinter Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05479
  • [Presentation] 蝸牛器官培養聴神経障害モデルにおけるROCK阻害薬の効果の検討2019

    • Author(s)
      小泉優, 伊藤吏, 欠畑誠治
    • Organizer
      日本耳科学会
    • Data Source
      KAKENHI-PROJECT-17K19713
  • [Presentation] 蝸牛器官培養聴神経障害モデルを用いた聴神経の再生2019

    • Author(s)
      小泉優, 伊藤吏, 欠畑誠治
    • Organizer
      日本耳鼻咽喉科学会東北地方連合学術講演会
    • Data Source
      KAKENHI-PROJECT-17K19713
  • [Presentation] 蝸牛器官培養聴神経障害モデルを用いた聴神経の再生2018

    • Author(s)
      小泉優, 伊藤吏, 欠畑誠治
    • Organizer
      日本耳科学会
    • Data Source
      KAKENHI-PROJECT-16H05479
  • [Presentation] The Influence of Sleep Stage on Auditory Steady-State Response2011

    • Author(s)
      ITO Tsukasa
    • Organizer
      The Association for Research in Otolaryngology 34th MidWinter Meeting
    • Place of Presentation
      Baltimore, Maryland, USA
    • Year and Date
      2011-02-21
    • Data Source
      KAKENHI-PROJECT-21791591
  • [Presentation] The Influence of Sleep Stage on Auditory Steady-State Response, The Association for Research in Otolaryngology2011

    • Author(s)
      ITO Tsukasa
    • Organizer
      34th MidWinter Meeting
    • Place of Presentation
      Baltimore, Maryland, USA
    • Year and Date
      2011-02-21
    • Data Source
      KAKENHI-PROJECT-21791591
  • [Presentation] 聴性定常反応ASSRに対する睡眠深度の影響2010

    • Author(s)
      伊藤吏
    • Organizer
      第55回 日本聴覚医学会
    • Place of Presentation
      奈良県 新公会堂
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-21791591
  • [Presentation] 聴性定常反応ASSRに対する睡眠深度の影響2010

    • Author(s)
      伊藤吏
    • Organizer
      第55回日本聴覚医学会
    • Place of Presentation
      奈良市
    • Year and Date
      2010-11-11
    • Data Source
      KAKENHI-PROJECT-21791591
  • [Presentation] Chirp 音を用いたASSR の有用性

    • Author(s)
      千葉寛之,伊藤吏,渡辺知緒,窪田俊憲,欠畑誠治
    • Organizer
      第59回 日本聴覚医学会
    • Place of Presentation
      山口県下関市 海峡メッセ下関
    • Year and Date
      2014-11-27 – 2014-11-28
    • Data Source
      KAKENHI-PROJECT-24592540
  • 1.  KUBOTA Toshinori (80536954)
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