Ito (Tsukasa 伊藤吏

… Alternative Names

ITO Tsukasa 伊藤吏

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Researcher Number	50344809
Other IDs	https://orcid.org/0000-0002-4237-3564
External Links
Affiliation (Current)	2023: 山形大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 山形大学, 医学部, 准教授 2014 – 2016: 山形大学, 医学部, 講師 2014: 山形大学, 医学部, 助教 2013: 山形大学, 医学部, 非常勤講師 2012: 山形大学, 医学部, 助教 2009 – 2010: Yamagata University, 医学部, 助教 2002 – 2006: 山形大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related / Surgery related to the biological and sensory functions and related fields / Otorhinolaryngology
Keywords	Principal Investigator 中耳真珠腫 / 中耳粘膜再生 / 経外耳道的内視鏡下耳科手術 / 再生医療 / モルモット / 線毛上皮 / 中耳粘膜 / 真珠腫性中耳炎 / 内視鏡下耳科手術 / 小児難聴 … More / 他覚的聴力検査 / 聴性定常反応 / 線毛円柱上皮 / レチノイド / 低侵襲手術 / 慢性中耳炎 / 間葉系幹細胞 / 真珠製中耳炎 / HMGB1 / 睡眠深度 / 聴性定常反応(ASSR) / 精密聴力検査 / 新生児聴覚スクリーニング / 睡眠 / 受精因子 / 頭頚部癌 / mRNA / 酵素活性 / 頭頸部癌 / Thymidylate Synthase / Orotate Phosphoribosyl Transferase / DihydroPyrimidine Dehydrogenase / 5-FU … More Except Principal Investigator 内耳 / シナプス再生 / ROCK阻害薬 / 再生 / 有毛細胞 / 聴神経 / 感音難聴 / 再生医学 / 神経 / シナプス / 幹細胞 / 音響暴露 / 内耳再生 / 難聴 / 内耳障害 / RT-PCR / DGK inhibitor / ジアシルグリセロールキナーゼ / EarFlow / 蝸牛シナプス障害 / 側頭骨病理 / 小胞体 / 血管条 / コルチ器 / 副腎皮質ホルモン / Cochlear synaptopathy / cochlear synaptopathy / 蝸牛神経 / 内有毛細胞 / 聴覚再生 / 耳科学 / 内耳3次元器官培養 / 多能性幹細胞 / 再生医療 / 外有毛細胞 / 聴覚 / 幹細胞移植 / cell growth / specific antibody / human malignant tumor cells / diacylglycerol kinase / protein kinase C / diacylglycerol / 扇平上皮癌 / 甲状腺癌 / 扁平上皮癌 / 頭頚部癌 / 細胞増殖 / 特異抗体 / プロテインキナーゼC / 頭頸部悪性腫瘍 / multiple amplitude-modulated tones / amplitude-modulation following response / steady-state response / 他覚的聴力検査 / 他覚的聴力検査装置 / 複合振幅変調音 / 変調周波数追随反応 / 聴性定常反応 / Matrigel / 神経再生 / ヒト皮膚繊維芽細胞 / 顔面神経損傷モデル / ラット / 機能再生 / ヒト皮膚線維芽細胞 / 顔面神経麻痺 / 聴覚医学 Less

EarFlowを用いた蝸牛シナプス障害に対する新規治療の確立
- Principal Investigator
  
  欠畑誠治
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yamagata University
Development of a Fundamental Therapeutic Approach for the Treatment of Middle Ear Cholesteatoma Using Technology of Regeneration and Induction of Differentiation of Middle Ear MucosaPrincipal Investigator
- Principal Investigator
  
  伊藤吏
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yamagata University
聴神経・シナプス再生の細胞内メカニズムの解明
- Principal Investigator
  
  天野彰子
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yamagata University
難聴治療の挑戦 -内耳における小胞体・リン脂質代謝酵素および再生因子の解析-
- Principal Investigator
  
  松井祐興
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yamagata University
低侵襲な中耳粘膜再生技術による中耳真珠腫根治へ向けての研究Principal Investigator
- Principal Investigator
  
  伊藤吏
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yamagata University
内有毛細胞・蝸牛神経間シナプスをターゲットとした聴覚再生治療の新規開発
- Principal Investigator
  
  欠畑誠治
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yamagata University
Study for the curative treatment of middle ear cholesteatoma by regeneration of middle ear mucosa using autologous stem cell inductionPrincipal Investigator
- Principal Investigator
  
  Ito Tsukasa
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamagata University
Challenge to development of new regenerative therapy targeting synapses between hair cells and auditory nerve fibers
- Principal Investigator
  
  Kakehata Seiji
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  Yamagata University
永続型耳鳴治療（埋込型岬角電気刺激装置）をめざして
- Principal Investigator
  
  WATANABE Tomoo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamagata University
Multifaceted analysis of inner ear regeneration using Muse cells
- Principal Investigator
  
  kakehata seiji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamagata University
Challenges for effective delivery of stem cells to the organ of Corti
- Principal Investigator
  
  Kakehata Seiji
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamagata University
Effect of transplanting normal human dermal fibroblasts (NHDF) in the rat facial nerve palsy model
- Principal Investigator
  
  KAKEHATA Seiji
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamagata University
Development of Novel Objective Audiometry Based on Auditory Steady State Response and Sleep Stage AnalysisPrincipal Investigator
- Principal Investigator
  
  ITO Tsukasa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamagata University
The research and development of the new objective audiometry technique using an auditory steady-state response (ASSR) in sleeping subjectsPrincipal Investigator
- Principal Investigator
  
  ITO Tsukasa
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamagata University
頭頚部癌における5-FU感受性因子の新しい定量法の開発とその有用性に関する検討Principal Investigator
- Principal Investigator
  
  伊藤吏
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamagata University
Immunohistochemical and molecular biological study on expression of diacylglycrol kinase in human origined malignant tumor cells from head and neck
- Principal Investigator
  
  KOIKE Shuji
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamagata University School of Medicine
Clinical Application of Auditory Steady-State Response evoked by multiple simultaneous amplitude-modulated stimuli (amplitude-modulation following response : AMFR) for Assessment of hearing in infants and young children
- Principal Investigator
  
  WATANABE Tomoo, SUZUKI Yutaka
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamagata-uniersity

All 2021 2020 2019 2018 2011 2010 2005 2004 2003 Other

All Journal Article Presentation

[Journal Article] Consistent removal of hair cells in vestibular end organs by time-dependent transtympanic administration of gentamicin in guinea pigs2021
- Author(s)
  Chiba Makoto、Ito Tsukasa、Shinkawa Chikako、Koizumi Yutaka、Hull Melinda、Kakehata Seiji
- Journal Title
  
  Journal of Neuroscience Methods
  
  Volume: 351 Pages: 109049-109049
- DOI
  10.1016/j.jneumeth.2020.109049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16887, KAKENHI-PROJECT-20H03833
[Journal Article] Regenerative Effect of a ROCK Inhibitor, Y-27632, on Excitotoxic Trauma in an Organotypic Culture of the Cochlea2020
- Author(s)
  Koizumi Y, Ito T, Mizutari K, Kakehata S.
- Journal Title
  
  Front. Cell. Neurosci.
  
  Volume: 14 Pages: 572434-572434
- DOI
  10.3389/fncel.2020.572434
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09335, KAKENHI-PROJECT-20KK0204, KAKENHI-PROJECT-17K19713, KAKENHI-PROJECT-17K16887, KAKENHI-PROJECT-20H03833
[Journal Article] Expression and localization of diacylglycerol kinase ζ in guinea pig cochlea and its functional implication under noise-exposure stress conditions2019
- Author(s)
  Shinkawa C, Ito T, Hozumi Y, Chiba M, Matsui H, Goto K, Kakehata S
- Journal Title
  
  Histochem Cell Biol.
  
  Volume: epub Issue: 6 Pages: 461-474
- DOI
  10.1007/s00418-019-01781-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05479, KAKENHI-PROJECT-17K08507
[Journal Article] 聴力正常者におけるASSRの刺激音圧とパワー・潜時・CSMの関係2010
- Author(s)
  窪田俊憲, 伊藤吏, 渡辺知緒, 阿部靖弘, 千葉寛之, 井川信子, 鈴木豊, 青柳優
- Journal Title
  
  ASSRを用いた補充現象解析へむけて.Audiology Japan 53
  
  Pages: 266-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791591
[Journal Article] Gene expression, cellular localization, and enzymatic activity of diacylglycerol kinase isozymes in rat ovary and placenta.2005
- Author(s)
  Toya M, Hozumi Y, Ito T, Takeda M, Sakane F, Kanoh H, Saito H, Hiroi M, Kurachi H, Kondo H, Goto K.
- Journal Title
  
  Cell Tissue Res. Jun;320(3)
  
  Pages: 525-533
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591795
[Journal Article] Expression and localization of diacylglycerol kinase isozymes and enzymatic features in rat lung.2005
- Author(s)
  Katagiri Y, Ito T, Saino-Saito S, Hozumi Y, Suwabe A, Otake K, Sata M, Kondo H, Sakane F, Kanoh H, Kubota I, Goto K.
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol. Jun;288(6)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591795
[Journal Article] Cloning and characterization of DGKι splice variants in rat brain.2004
- Author(s)
  Ito T, Hozumi Y, et al.
- Journal Title
  
  J Biol Chem. 279(22)
  
  Pages: 23317-23326
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591795
[Journal Article] Cloning and characterization of diacylglycerol kinase iota splice variants in rat brain.2004
- Author(s)
  Ito T, Hozumi Y, Sakane F, Saino-Saito S, Kanoh H, Aoyagi M, Kondo H, Goto K.
- Journal Title
  
  J Biol Chem. May 28;279(22)
  
  Pages: 23317-23326
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591795
[Journal Article] Nuclear localization of diacylglycerol kinase zeta in neurons.2003
- Author(s)
  Hozumi Y, Ito T, et al.
- Journal Title
  
  Eur J Neurosci 18(6)
  
  Pages: 1448-1457
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591795
[Journal Article] Nuclear localization of diacylglycerol kinase zeta in neurons.2003
- Author(s)
  Hozumi Y, Ito T, Nakano T, Nakagawa T, Aoyagi M, Kondo H, Goto K.
- Journal Title
  
  Eur J Neurosci. Sep;18(6)
  
  Pages: 1448-1457
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591795
[Presentation] COVID-19感染予防対策における音の遮蔽と語音聴取に対する影響についての検討2021
- Author(s)
  松井祐興、伊藤吏、窪田俊憲、新川智佳子、天野彰子、千葉寛之、石山弘将、綿貫敬介、不破大介、欠畑誠治
- Organizer
  第66回　日本聴覚医学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-21K09649
[Presentation] Laser-induced shock waveによるcochlear synaptopathyモデルに対するROCK阻害薬の効果の検討2021
- Author(s)
  小泉優, 水足邦雄, 伊藤吏, 塩谷彰浩, 欠畑誠治
- Organizer
  第31回日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20H03833
[Presentation] Cochlear synaptopathy をターゲットとした治療法開発への試み～当科での内耳基礎研究について～2021
- Author(s)
  小泉優 , 伊藤 , 吏 , 窪田俊憲 , 松井祐興 , 新川智佳子 , 寺田小百合 , 天野彰子 , 欠畑誠治
- Organizer
  第６回耳鳴・難聴研究会
- Data Source
  KAKENHI-PROJECT-20H03833
[Presentation] 実験動物モデルにおける ABR を用いた伝音難聴と感音難聴の鑑別について2021
- Author(s)
  寺田小百合 , 伊藤吏 , 新川智佳子 , 小泉優 , 天野彰子 , 松井祐興 , 窪田俊憲 , 欠畑誠治
- Organizer
  第１回 ERA・ERP 研究会
- Data Source
  KAKENHI-PROJECT-20H03833
[Presentation] レチノイドを用いた中耳粘膜上皮の創傷治癒効果について2021
- Author(s)
  寺田小百合, 伊藤吏, 小泉優, 天野彰子, 新川智佳子, 欠畑誠治
- Organizer
  第31回日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20H03833
[Presentation] レチノイドを用いた中耳粘膜上皮の創傷治癒効果について2021
- Author(s)
  寺田小百合，伊藤吏，小泉優，天野彰子，新川智佳子，欠畑誠治
- Organizer
  第 31 回日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20K09725
[Presentation] ROCK inhibitor Y-27632 accelerates auditory nerve fiber growth and synapse formation after excitotoxic trauma in organotypic culture of cochlea2019
- Author(s)
  Yutaka Koizumi, Tsukasa Ito, Seiji Kakehata
- Organizer
  Association for Research in Otolaryngology 42nd Annual MidWinter Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05479
[Presentation] 蝸牛器官培養聴神経障害モデルにおけるROCK阻害薬の効果の検討2019
- Author(s)
  小泉優, 伊藤吏, 欠畑誠治
- Organizer
  日本耳科学会
- Data Source
  KAKENHI-PROJECT-17K19713
[Presentation] 蝸牛器官培養聴神経障害モデルを用いた聴神経の再生2019
- Author(s)
  小泉優, 伊藤吏, 欠畑誠治
- Organizer
  日本耳鼻咽喉科学会東北地方連合学術講演会
- Data Source
  KAKENHI-PROJECT-17K19713
[Presentation] 蝸牛器官培養聴神経障害モデルを用いた聴神経の再生2018
- Author(s)
  小泉優, 伊藤吏, 欠畑誠治
- Organizer
  日本耳科学会
- Data Source
  KAKENHI-PROJECT-16H05479
[Presentation] The Influence of Sleep Stage on Auditory Steady-State Response2011
- Author(s)
  ITO Tsukasa
- Organizer
  The Association for Research in Otolaryngology 34th MidWinter Meeting
- Place of Presentation
  Baltimore, Maryland, USA
- Year and Date
  2011-02-21
- Data Source
  KAKENHI-PROJECT-21791591
[Presentation] The Influence of Sleep Stage on Auditory Steady-State Response, The Association for Research in Otolaryngology2011
- Author(s)
  ITO Tsukasa
- Organizer
  34th MidWinter Meeting
- Place of Presentation
  Baltimore, Maryland, USA
- Year and Date
  2011-02-21
- Data Source
  KAKENHI-PROJECT-21791591
[Presentation] 聴性定常反応ASSRに対する睡眠深度の影響2010
- Author(s)
  伊藤吏
- Organizer
  第55回日本聴覚医学会
- Place of Presentation
  奈良県新公会堂
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21791591
[Presentation] 聴性定常反応ASSRに対する睡眠深度の影響2010
- Author(s)
  伊藤吏
- Organizer
  第55回日本聴覚医学会
- Place of Presentation
  奈良市
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21791591
[Presentation] Chirp 音を用いたASSR の有用性
- Author(s)
  千葉寛之，伊藤吏，渡辺知緒，窪田俊憲，欠畑誠治
- Organizer
  第59回　日本聴覚医学会
- Place of Presentation
  山口県下関市海峡メッセ下関
- Year and Date
  2014-11-27 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-24592540

1. KUBOTA Toshinori (80536954)

# of Collaborated Projects: 9 results

# of Collaborated Products: 5 results
2. KAKEHATA Seiji (90261619)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
3. WATANABE Tomoo (60344793)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. 天野彰子 (50787249)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
5. FURUKAWA Takatoshi (80466630)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. 小泉優 (80723585)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
7. 寺田小百合 (40795697)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
8. SUZUKI Yutaka (70250925)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 杉山元康 (60637255)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 松井祐興 (60594322)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. 新川智佳子 (00571647)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. AOYAGI Masaru (40107181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOIKE Shuji (10205297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. GOTO Kaoru (30234975)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
15. HOZUMI Yasukazu (00372334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
16. 伊藤智史 (80332542)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 布施健生 (00167628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 水足邦雄 (40338140)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 後藤崇成 (50571642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ito (Tsukasa 伊藤 吏

ITO Tsukasa 伊藤 吏

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Development of a Fundamental Therapeutic Approach for the Treatment of Middle Ear Cholesteatoma Using Technology of Regeneration and Induction of Differentiation of Middle Ear MucosaPrincipal Investigator

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低侵襲な中耳粘膜再生技術による中耳真珠腫根治へ向けての研究Principal Investigator

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Study for the curative treatment of middle ear cholesteatoma by regeneration of middle ear mucosa using autologous stem cell inductionPrincipal Investigator

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Development of Novel Objective Audiometry Based on Auditory Steady State Response and Sleep Stage AnalysisPrincipal Investigator

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The research and development of the new objective audiometry technique using an auditory steady-state response (ASSR) in sleeping subjectsPrincipal Investigator

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Ito (Tsukasa 伊藤吏

ITO Tsukasa 伊藤吏