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Kanouchi Tadashi  叶内 匡

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KANOUCHI Tadashi  叶内 匡

叶内 匡  カノウチ タダシ

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Researcher Number 50345287
Other IDs
Affiliation (Current) 2022: 東京医科歯科大学, 東京医科歯科大学病院, 講師
Affiliation (based on the past Project Information) *help 2016 – 2019: 東京医科歯科大学, 医学部附属病院, 講師
2012: 東京医科歯科大学, 医学部附属病院, 助教
2007 – 2008: 東京医科歯科大学, 医学部附属病院, 助教
2007: Tokyo Medical and Dental University, 医学部付属病院, 助教
2006: 東京医科歯科大学, 医学部附属病院, 助手
2002: TOKYO MEDICAL AND DENTAL UNIVERSITY, DEPARTMENT OF NEUROLOGY AND NEUROLOGICAL SCIENCE, ASSISTANT LECTURER, 医学部附属病院, 助手
Review Section/Research Field
Principal Investigator
Neurology / Neurochemistry/Neuropharmacology / Laboratory animal science
Except Principal Investigator
Community health/Gerontological nurisng / Neurology
Keywords
Principal Investigator
RNAi / ビタミンE / 遺伝子治療 / siRNA / トランスジェニックマウス / shRNA / SOD1 / モデルマウス / shRNA毒性 / ALS … More / ラット / TDP-43 / 伝播 / 筋委縮性側索硬化症 / プリオン様伝播仮説 / 病変進展 / 定量的疾患進行パターン / Local progression / Regional spread / 電気生理学的検査 / 筋萎縮性側索硬化症 / 局所進行 / 領域進展 / 複合筋活動電位 / 針筋電図 / 経頭蓋磁気刺激(三重刺激法) / プリオン様伝搬仮説 / 疾患進行パターン / 電気生理 / local progression / regional spread / 脳神経疾患 / 進行パターン / 臨床電気生理学的手法 … More
Except Principal Investigator
SCA6 / CACNA1A / αTTP / 摂食・嚥下障害 / トレーニング / 予防 / 介入 / 効果 / 測定 / トレーニングプログラム / 基準作成 / 非侵襲検査 / 脊髄小脳変性症 / CAGリピート / Caチャンネル / プルキンエ細胞 / 動物モデル / CAGピート / ノックインマウス / CACN1A / 脊髄小脳変形症 / ES細胞 / CACNAIA / SPINOCEREBELLAR DEGENERATION / CAG REPEAT / CA CHANNEL / PURKINJE CELL / ANIMAL MODEL Less
  • Research Projects

    (6 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (10 People)
  •  A novel analysis of the disease progression patterns in ALS using electrophysiological dataPrincipal Investigator

    • Principal Investigator
      Kanouchi Tadashi
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tokyo Medical and Dental University
  •  Development of rat model of TDP-43 propagationPrincipal Investigator

    • Principal Investigator
      KANOUCHI Tadashi
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Tokyo Medical and Dental University
  •  あらゆる遺伝子を標的にできるsiRNAトランスジェニックマウスの新規作製方法Principal Investigator

    • Principal Investigator
      叶内 匡
    • Project Period (FY)
      2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Medical and Dental University
  •  ビタミンEを用いたsiRNAの脳への新しいデリバリー法の開発Principal Investigator

    • Principal Investigator
      叶内 匡
    • Project Period (FY)
      2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tokyo Medical and Dental University
  •  摂食・嚥下障害予防のためのトレーニングプログラム開発・介入基準作成および効果測定

    • Principal Investigator
      千葉 由美
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Community health/Gerontological nurisng
    • Research Institution
      Tokyo Medical and Dental University
  •  STUDIES ON MOLECULAR AND CLINICAL PATHOMECHANISM OF SPINOCEREBELLAR DEGENERATION

    • Principal Investigator
      MIZUSAWA Hidehiro
    • Project Period (FY)
      2000 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurology
    • Research Institution
      Tokyo Medical and Dental University

All 2017 2016 2012 2008

All Journal Article Presentation

  • [Journal Article] Can regional spreading of amyotrophic lateral sclerosis motor symptoms be explained by prion-like propagation?2012

    • Author(s)
      Kanouchi T, Ohkubo T, Yokota T
    • Journal Title

      J Neurol Neurosurg Psychiatry.

      Volume: vol. 83, No. 7 Pages: 739-45

    • DOI

      10.1136/jnnp-2011-301826

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22240039, KAKENHI-PROJECT-24659425, KAKENHI-PROJECT-24689039
  • [Journal Article] Can regional spreading of amyotrophic lateral sclerosis motor symptoms be explained by prion-like propagation?2012

    • Author(s)
      Kanouchi T, Ohkubo T, Yokota T
    • Journal Title

      J Neurol Neurosurg Psychiatry

      Volume: 83 Pages: 739-45

    • Data Source
      KAKENHI-PROJECT-24659425
  • [Journal Article] Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol2008

    • Author(s)
      Kazutaka Nishina, Toshinori Unno, Yoshitaka Uno, Takayuki Kubodera, Tadashi Kanouchi, Hidehiro Mizusawa Takanori Yokota
    • Journal Title

      Molecular Therapy 16

      Pages: 734-740

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19650103
  • [Presentation] Temporal relation between local disease progression in the onset site and regional spread of motor symptoms in amyotrophic lateral sclerosis.2017

    • Author(s)
      Kanouchi T, Sekiguchi T, Iida S, Akaza M, Yokota T.
    • Organizer
      The XXIII World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09710
  • [Presentation] 新たな視点による筋萎縮性側索硬化症(ALS)の進行様式に関する定量解 析の試み2016

    • Author(s)
      叶内 匡,関口輝彦,横田隆徳
    • Organizer
      第57 回日本神経学会学術大会
    • Place of Presentation
      神戸コンペンションセンター・神戸ポートピアホテル(兵庫県神戸市)
    • Data Source
      KAKENHI-PROJECT-16K09710
  • [Presentation] 筋萎縮性側索硬化症(ALS)における下位運動神経の障害速度 に上位運動神経障害は影響するか2016

    • Author(s)
      叶内 匡,関口輝彦,東田修二,横田隆徳
    • Organizer
      第46 回日本臨床神経生理学会学術大会
    • Place of Presentation
      ホテルハマツ(福島県郡山市)
    • Data Source
      KAKENHI-PROJECT-16K09710
  • 1.  YOKOTA Takanori (90231688)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 2.  OHKUBO Takuya (90587461)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 3.  MIZUSAWA Hidehiro (30144091)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  ISHIKAWA Kinya (30313240)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  千葉 由美 (10313256)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  戸原 玄 (00396954)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  森田 定雄 (20202426)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  植松 宏 (80100957)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  山脇 正永 (30302855)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  大和田 潔 (40313241)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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