KANOUCHI Tadashi 叶内匡

Researcher Number	50345287
Other IDs
Affiliation *help	2016 – 2018 : 東京医科歯科大学, 医学部附属病院, 講師 2012 : 東京医科歯科大学, 医学部附属病院, 助教 2007 – 2008 : 東京医科歯科大学, 医学部附属病院, 助教 2007 : Tokyo Medical and Dental University, 医学部付属病院, 助教 2006 : 東京医科歯科大学, 医学部附属病院, 助手 2002 : TOKYO MEDICAL AND DENTAL UNIVERSITY, DEPARTMENT OF NEUROLOGY AND NEUROLOGICAL SCIENCE, ASSISTANT LECTURER, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Neurology / Neurochemistry/Neuropharmacology / Laboratory animal science Except Principal Investigator Community health/Gerontological nurisng / Neurology
Keywords	Principal Investigator shRNA毒性 / 筋萎縮性側索硬化症 / 電気生理 / RNAi / regional spread / siRNA / プリオン様伝播仮説 / 遺伝子治療 / モデルマウス / 病変進展 … More Except Principal Investigator αTTP / CACNA1A / SCA6 / CACN1A / 脊髄小脳変性症 / PURKINJE CELL / 基準作成 / SPINOCEREBELLAR DEGENERATION / CA CHANNEL / 動物モデル / 測定 / 非侵襲検査 / 予防 / ノックインマウス / ES細胞 / CAGピート / CAGリピート / プルキンエ細胞 / 介入 / Caチャンネル / トレーニングプログラム / CACNAIA / 摂食・嚥下障害 / CAG REPEAT / トレーニング / ANIMAL MODEL / 効果 / 脊髄小脳変形症 Less

新たな視点によるALSの進行パターンの電気生理学的探索Principal InvestigatorOngoing
- Principal Investigator
  
  叶内匡
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Medical and Dental University
Development of rat model of TDP-43 propagationPrincipal Investigator
- Principal Investigator
  
  KANOUCHI Tadashi
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Tokyo Medical and Dental University
あらゆる遺伝子を標的にできるsiRNAトランスジェニックマウスの新規作製方法Principal Investigator
- Principal Investigator
  
  叶内匡
- Project Period (FY)
  2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Tokyo Medical and Dental University
ビタミンEを用いたsiRNAの脳への新しいデリバリー法の開発Principal Investigator
- Principal Investigator
  
  叶内匡
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Tokyo Medical and Dental University
摂食・嚥下障害予防のためのトレーニングプログラム開発・介入基準作成および効果測定
- Principal Investigator
  
  千葉由美
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Community health/Gerontological nurisng
- Research Institution
  Tokyo Medical and Dental University
STUDIES ON MOLECULAR AND CLINICAL PATHOMECHANISM OF SPINOCEREBELLAR DEGENERATION
- Principal Investigator
  
  MIZUSAWA Hidehiro
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Neurology
- Research Institution
  Tokyo Medical and Dental University

All 2017 2016 2012 2008

All Journal Article Presentation

[Journal Article] Can regional spreading of amyotrophic lateral sclerosis motor symptoms beexplained by prion-like propagation?2012
- Author(s)
  Kanouchi T
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume : 83 Pages : 739-745
- DOI
  10.1136/jnnp-2011-301826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22240039, KAKENHI-PROJECT-24659425, KAKENHI-PROJECT-24689039
[Journal Article] Can regional spreading of amyotrophic lateral sclerosis motor symptoms be explained by prion-like propagation?2012
- Author(s)
  Kanouchi T, Ohkubo T, Yokota T
- Journal Title
  
  J Neurol Neurosurg Psychiatry
  
  Volume : 83 Pages : 739-45
- Data Source
  KAKENHI-PROJECT-24659425
[Journal Article] Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol2008
- Author(s)
  Kazutaka Nishina, Toshinori Unno, Yoshitaka Uno, Takayuki Kubodera, Tadashi Kanouchi, Hidehiro Mizusawa Takanori Yokota
- Journal Title
  
  Molecular Therapy 16
  
  Pages : 734-740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19650103
[Presentation] Temporal relation between local disease progression in the onset site and regional spread of motor symptoms in amyotrophic lateral sclerosis.2017
- Author(s)
  Kanouchi T, Sekiguchi T, Iida S, Akaza M, Yokota T.
- Organizer
  The XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09710
[Presentation] 新たな視点による筋萎縮性側索硬化症（ALS）の進行様式に関する定量解析の試み2016
- Author(s)
  叶内　匡，関口輝彦，横田隆徳
- Organizer
  第57 回日本神経学会学術大会
- Place of Presentation
  神戸コンペンションセンター・神戸ポートピアホテル（兵庫県神戸市）
- Data Source
  KAKENHI-PROJECT-16K09710
[Presentation] 筋萎縮性側索硬化症（ALS）における下位運動神経の障害速度に上位運動神経障害は影響するか2016
- Author(s)
  叶内　匡，関口輝彦，東田修二，横田隆徳
- Organizer
  第46 回日本臨床神経生理学会学術大会
- Place of Presentation
  ホテルハマツ（福島県郡山市）
- Data Source
  KAKENHI-PROJECT-16K09710

1. YOKOTA Takanori (90231688)

# of Collaborated Projects : 4results

# of Collaborated Products : 2results
2. OHKUBO Takuya (90587461)

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
3. MIZUSAWA Hidehiro (30144091)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
4. ISHIKAWA Kinya (30313240)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. 千葉由美 (10313256)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
6. 戸原玄 (00396954)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. 森田定雄 (20202426)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. 植松宏 (80100957)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
9. 山脇正永 (30302855)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. 大和田潔 (40313241)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results

KANOUCHI Tadashi 叶内 匡

Research Projects

Research Products

Co-Researchers

新たな視点によるALSの進行パターンの電気生理学的探索Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of rat model of TDP-43 propagationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

あらゆる遺伝子を標的にできるsiRNAトランスジェニックマウスの新規作製方法Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ビタミンEを用いたsiRNAの脳への新しいデリバリー法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

摂食・嚥下障害予防のためのトレーニングプログラム開発・介入基準作成および効果測定

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

STUDIES ON MOLECULAR AND CLINICAL PATHOMECHANISM OF SPINOCEREBELLAR DEGENERATION

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Can regional spreading of amyotrophic lateral sclerosis motor symptoms beexplained by prion-like propagation?2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Can regional spreading of amyotrophic lateral sclerosis motor symptoms be explained by prion-like propagation?2012

Author(s)

Journal Title

Data Source

[Journal Article] Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol2008

Author(s)

Journal Title

Data Source

[Presentation] Temporal relation between local disease progression in the onset site and regional spread of motor symptoms in amyotrophic lateral sclerosis.2017

Author(s)

Organizer

Data Source

[Presentation] 新たな視点による筋萎縮性側索硬化症（ALS）の進行様式に関する定量解 析の試み2016

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 筋萎縮性側索硬化症（ALS）における下位運動神経の障害速度 に上位運動神経障害は影響するか2016

Author(s)

Organizer

Place of Presentation

Data Source

KANOUCHI Tadashi 叶内匡

[Presentation] 新たな視点による筋萎縮性側索硬化症（ALS）の進行様式に関する定量解析の試み2016

[Presentation] 筋萎縮性側索硬化症（ALS）における下位運動神経の障害速度に上位運動神経障害は影響するか2016