Yamaguchi Yuuki 山口雄輝

… Alternative Names

YAMAGUCHI Yuki 山口雄輝

山口雄輝ヤマグチユウキ

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Researcher Number	50345360
Other IDs
Affiliation (Current)	2025: 東京科学大学, 生命理工学院, 教授
Affiliation (based on the past Project Information) *help	2024: 東京工業大学, 生命理工学院, 教授 2015 – 2022: 東京工業大学, 生命理工学院, 教授 2013 – 2014: 東京工業大学, 生命理工学研究科, 教授 2012 – 2013: 東京工業大学, 生命理工学研究科, 准教授 2009: 東京工業大学, 生命理工学部, 助教授 … More 2008: 東京工業大学, 大学院・生命理工学研究科, 准教授 2007: Tokyo Institute of Technology, 大学院・生命理工学研究科, 助教 2006: 東京工業大学, 大学院生命理工学研究科, 助手 2003 – 2005: 東京工業大学, 大学院・生命理工学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Biological Sciences / Molecular biology / Basic Section 43050:Genome biology-related / Basic Section 43010:Molecular biology-related Except Principal Investigator Biological Sciences / Basic Section 52050:Embryonic medicine and pediatrics-related / Biomolecular chemistry
Keywords	Principal Investigator 生体生命情報学 / 発現制御 / 遺伝子 / プロテオーム解析 / proximity labeling / 転写複合体 / ポリA付加 / 遺伝学的スクリーニング / ポリ(A)付加 / 転写終結 … More / 分子間相互作用 / クロマチン / RNAプロセシング / 転写 / 核内構造 / 選択的RNAプロセシング / 転写伸長 / RNAポリメラーゼII / 酵素 / 発生・分化 / １分子計測 / 分子認識 / 転写サイクル / ケミカルバイオロジー / 生体高分子構造・機能 / ブロテオーム解析 / タンパク質間相互作用 / クロスリンカー / ケミカルパイオロジー / 生体高分子構造・磯能 / 胎性致死 / ノックアウトマウス / NELF / 転写伸長因子 … More Except Principal Investigator ゼブラフィッシュ / 転写 / フェロトーシス / 細胞死 / 酸化ストレス / MELAS / Leigh脳症 / ミトコンドリア / 非アルコール性脂肪性肝疾患 / アルツハイマー病 / パーキンソン病 / ミトコンドリア病 / アポモルフィン / 薬学 / 生体分子 / 再生医学 / 発生・分化 / 脳・神経 / 活性発現の分子構造 / 活性発現の分子機構 / ヒト型ゼブラフィッシュ / 脳発達 / ヒトiPS細胞 / サリドマイド誘導体 / セレブロン / CRBN / 神経幹細胞 / iPS細胞 / 脳発生 / CRBN作動薬 / サリドマイド / セレブロン(CRBN) / RNAポリメラーゼ / RNA / ヘテロクロマチン / 転写伸長 / RNAプロセシング / クロマチン / RNAポリメラーゼII / 生体生命情報学 / 蛋白質 / マイクロアレイ / サイトカイン / 生化学 / 構造 / 遺伝子 / ゼブラフイッシュ / マイクロアイレ / 分化 / 発現抑制 / ノックアウトマウス / タンパク質 / 遺電子 Less

Structure-function analysis of transcription elongation/termination complexes using a new method capable of analyzing multifactor complexesPrincipal Investigator
- Principal Investigator
  
  山口雄輝
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Tokyo Institute of Technology
Elucidation of the selection mechanism of transcription termination and polyadenylation sites by using novel proteomic approachPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Yuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Tokyo Institute of Technology
Elucidation of the mechanism of mitochondrial disease cell death inhibition and drug discovery
- Principal Investigator
  
  Osaka Hitoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Jichi Medical University
Search for novel modulators of cereblon, the target of thalidomide that regulates neural stem cell proliferation and deifferentiation
- Principal Investigator
  
  HANDA Hiroshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Tokyo Medical University
Promotion of the Transcription Cycle AreaPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Yuki
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Institute of Technology
Elucidation of control mechanisms of transcriptional checkpoint during Pol II elongation, termination, and recyclePrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Yuki
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Institute of Technology
Integral understanding of the mechanism of transcription cycle through quantitative, high-resolution approachesArea Organizer
- Area Organizer
  
  山口雄輝
- Project Period (FY)
  2012 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
Regulation of fate-determination of RNA and role of transcriptional machinery in heterochromatin formatin
- Principal Investigator
  
  MURAKAMI Yota
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
生細胞内(insitu)でタンパク質間の相互作用を解析・同定する新規な方法の開発Principal Investigator
- Principal Investigator
  
  山口雄輝
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Institute of Technology
遺伝情報発現を転写伸長段階で制御するDECODE複合体の機能・構造解析
- Principal Investigator
  
  和田忠士
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Institute of Technology
ノックアウトマウスを用いた基本転写伸長因子の生理機能の解明Principal Investigator
- Principal Investigator
  
  山口雄輝
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Institute of Technology

[Book] 遺伝子発現制御機構クロマチン，転写制御，エピジェネティクス2017
- Author(s)
  田村隆明、浦清恵、山口雄輝ほか
- Total Pages
  264
- Publisher
  東京化学同人
- Data Source
  KAKENHI-ORGANIZER-24118001
[Book] 遺伝子発現制御機構クロマチン，転写制御，エピジェネティクス2017
- Author(s)
  田村隆明、浦清恵、山口雄輝ほか
- Total Pages
  264
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PLANNED-24118002
[Book] 基礎からしっかり学ぶ生化学2014
- Author(s)
  山口雄輝、成田央
- Total Pages
  245
- Publisher
  羊土社
- Data Source
  KAKENHI-PLANNED-24118002
[Book] 基礎からしっかり学ぶ生化学2014
- Author(s)
  山口雄輝、成田央
- Total Pages
  245
- Publisher
  羊土社
- Data Source
  KAKENHI-ORGANIZER-24118001
[Book] Hepstitis Delta Virus2006
- Author(s)
  Handa, H., Yamaguchi, Y.(Ed.)
- Total Pages
  94
- Publisher
  Landes Bioscience, Texas, USA
- Data Source
  KAKENHI-PROJECT-18770148
[Book] キーワードで理解する転写イラストマップ2004
- Author(s)
  山口雄輝(分担)
- Total Pages
  204
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15770107
[Journal Article] Integrator complex subunit 15 controls mRNA splicing and is critical for eye development2023
- Author(s)
  Noriyuki Azuma, Tadashi Yokoi, Taku Tanaka, Emiko Matsuzaka, Yuki Saida, Sachiko Nishina, Miho Terao, Shuji Takada, Maki Fukami, Kohji Okamura, Kayoko Maehara, Tokiwa Yamasaki, Jun Hirayama, Hiroshi Nishina, Hiroshi Handa, and Yuki Yamaguchi
- Journal Title
  
  Hum. Mol. Genet.
  
  Volume: ddad034 Issue: 12 Pages: 2032-2045
- DOI
  10.1093/hmg/ddad034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03182, KAKENHI-PROJECT-20H04565, KAKENHI-PROJECT-22K19606, KAKENHI-PROJECT-22K09848, KAKENHI-PROJECT-20H03845
[Journal Article] The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies2022
- Author(s)
  Suzuki Hidefumi、Abe Ryota、Shimada Miho、Hirose Tomonori、Hirose Hiroko、Noguchi Keisuke、Ike Yoko、Yasui Nanami、Furugori Kazuki、Yamaguchi Yuki、Toyoda Atsushi、Suzuki Yutaka、Yamamoto Tatsuro、Saitoh Noriko、Sato Shigeo、Tomomori-Sato Chieri、Conaway Ronald C.、Conaway Joan W.、Takahashi Hidehisa
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 2905-2905
- DOI
  10.1038/s41467-022-30632-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06482, KAKENHI-PROJECT-22K19466, KAKENHI-ORGANIZER-21H05158, KAKENHI-PLANNED-21H05159, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H03182, KAKENHI-PROJECT-20H03520, KAKENHI-PROJECT-21H02405, KAKENHI-PROJECT-20K06893, KAKENHI-PROJECT-21K19356, KAKENHI-PLANNED-18H05531
[Journal Article] Discovery of CRBN as a target of thalidomide: a breakthrough for progress in the development of protein degraders2022
- Author(s)
  Junichi Yamamoto, Takumi Ito, Yuki Yamaguchi, Hiroshi Handa
- Journal Title
  
  Chem. Soc. Rev.
  
  Volume: 51 Issue: 15 Pages: 6234-6250
- DOI
  10.1039/d2cs00116k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03182, KAKENHI-PROJECT-21H02955, KAKENHI-PLANNED-18H05502
[Journal Article] Three human RNA polymerases interact with TFIIH via a common RPB6 subunit2022
- Author(s)
  Okuda Masahiko、Suwa Tetsufumi、Suzuki Hidefumi、Yamaguchi Yuki、Nishimura Yoshifumi
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 50 Issue: 1 Pages: 1-16
- DOI
  10.1093/nar/gkab612
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15718, KAKENHI-PROJECT-20H03182
[Journal Article] PLZF and its fusion proteins are pomalidomide-dependent CRBN neosubstrates2021
- Author(s)
  Shimizu Nobuyuki、Asatsuma-Okumura Tomoko、Yamamoto Junichi、Yamaguchi Yuki、Handa Hiroshi、Ito Takumi
- Journal Title
  
  Communications Biology
  
  Volume: 4 Issue: 1 Pages: 1277-1277
- DOI
  10.1038/s42003-021-02801-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16314, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-20H03182, KAKENHI-PROJECT-21H02955
[Journal Article] Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology2021
- Author(s)
  Ito Takumi、Yamaguchi Yuki、Handa Hiroshi
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 28 Issue: 7 Pages: 987-999
- DOI
  10.1016/j.chembiol.2021.04.012
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-20H03182
[Journal Article] The role of Mediator and Little Elongation Complex in transcription termination2020
- Author(s)
  Takahashi H, Ranjan A, Chen S, Suzuki H, Shibata M, Hirose T, Hirose H, Sasaki K, Abe R, Chen K, He Y, Zhang Y, Takigawa I, Tsukiyama T, Watanabe M, Fujii S, Iida M, Yamamoto J, Yamaguchi Y, Suzuki Y, Matsumoto M, Nakayama KI, Washburn P, Saraf A, Florens L, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW, Hatakeyama S
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-20
- DOI
  10.1038/s41467-020-14849-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633, KAKENHI-PROJECT-19K22408, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-16K07105, KAKENHI-PROJECT-16H06279, KAKENHI-PUBLICLY-19H05280, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-20H03182, KAKENHI-PROJECT-19K22401
[Journal Article] ARID2 is a pomalidomide-dependent CRL4 CRBN substrate in multiple myeloma cells2020
- Author(s)
  Yamamoto J, Suwa T, Murase Y, Tateno S, Mizutome H, Asatsuma-Okumura T, Shimizu N, Kishi T, Momose S, Kizaki M, Ito T, Yamaguchi Y, Handa H.
- Journal Title
  
  Nat Chem Biol
  
  Volume: 16 Issue: 11 Pages: 1208-1217
- DOI
  10.1038/s41589-020-0645-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07396, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-20H03182, KAKENHI-PROJECT-19K16378
[Journal Article] Genome-wide screening reveals a role for subcellular localization of CRBN in the anti-myeloma activity of pomalidomide2020
- Author(s)
  Tateno Shumpei、Iida Midori、Fujii Satoshi、Suwa Tetsufumi、Katayama Miki、Tokuyama Haruka、Yamamoto Junichi、Ito Takumi、Sakamoto Satoshi、Handa Hiroshi、Yamaguchi Yuki
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 4012-4012
- DOI
  10.1038/s41598-020-61027-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-17H04213, KAKENHI-PROJECT-20H03182
[Journal Article] Application of high-performance magnetic nanobeads to biological sensing devices2019
- Author(s)
  Kabe Yasuaki、Sakamoto Satoshi、Hatakeyama Mamoru、Yamaguchi Yuki、Suematsu Makoto、Itonaga Makoto、Handa Hiroshi
- Journal Title
  
  Analytical and Bioanalytical Chemistry
  
  Volume: 411 Issue: 9 Pages: 1825-1837
- DOI
  10.1007/s00216-018-1548-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-18K06921
[Journal Article] p63 is a cereblon substrate involved in thalidomide teratogenicity2019
- Author(s)
  Asatsuma-Okumura Tomoko、Ando Hideki、De Simone Marco、Yamamoto Junichi、Sato Tomomi、Shimizu Nobuyuki、Asakawa Kazuhide、Yamaguchi Yuki、Ito Takumi、Guerrini Luisa、Handa Hiroshi
- Journal Title
  
  Nature Chemical Biology
  
  Volume: 15 Issue: 11 Pages: 1077-1084
- DOI
  10.1038/s41589-019-0366-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-18H05497, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-15H04288, KAKENHI-PROJECT-17H04213
[Journal Article] Cereblon Control of Zebrafish Brain Size by Regulation of Neural Stem Cell Proliferation2019
- Author(s)
  Hideki Ando, Tomomi Sato, Takumi Ito, Junichi Yamamoto, Satoshi Sakamoto, Nobuhiro Nitta, Tomoko Asatsuma-Okumura, Nobuyuki Shimizu, Ryota Mizushima, Ichio Aoki, Takeshi Imai, Yuki Yamaguchi, Arnold J Berk, and Hiroshi Handa
- Journal Title
  
  iScience
  
  Volume: 15 Pages: 95-108
- DOI
  10.1016/j.isci.2019.04.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09271, KAKENHI-PROJECT-17H06112, KAKENHI-PLANNED-18H05502, KAKENHI-PROJECT-17H04213
[Journal Article] TLP-mediated global transcriptional repression after double-strand DNA breaks slows down DNA repair and induces apoptosis.2019
- Author(s)
  Suzuki H, Okamoto-Katsuyama M, Suwa T, Maeda R, Tamura TA, Yamaguchi Y
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 4868-4868
- DOI
  10.1038/s41598-019-41057-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06112
[Journal Article] Structural basis of thalidomide enantiomer binding to cereblon.2018
- Author(s)
  Mori, T., Itoh, T., Liu, S., Ando, H., Sakamoto, S., Yamaguchi, Y., Tokunaga, E., Shibata, N., Handa, H. and Hakoshima, T.
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 1294-1294
- DOI
  10.1038/s41598-018-19202-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26251006, KAKENHI-PROJECT-15H04288, KAKENHI-PROJECT-17H04213, KAKENHI-PROJECT-17H06112
[Journal Article] 転写反応の生化学2017
- Author(s)
  山口雄輝
- Journal Title
  
  生体の科学
  
  Volume: 68(3)
- Data Source
  KAKENHI-ORGANIZER-24118001
[Journal Article] 転写反応の生化学2017
- Author(s)
  山口雄輝
- Journal Title
  
  生体の科学
  
  Volume: 68(3)
- Data Source
  KAKENHI-PLANNED-24118002
[Journal Article] Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.2016
- Author(s)
  Kabe Y, Nakane T, Koike I, Yamamoto T, Sugiura Y, Harada E, Sugase K, Shimamura T, Ohmura M, Muraoka K, Yamamoto A, Uchida T, Iwata S, Yamaguchi Y, Krayukhina E, Noda M, Handa H, Ishimori K, Uchiyama S, Kobayashi T, Suematsu M.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 11030-11030
- DOI
  10.1038/ncomms11030
- NAID
  130007529314
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07011, KAKENHI-PLANNED-23102002, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002, KAKENHI-PUBLICLY-26102725, KAKENHI-PROJECT-15H04338, KAKENHI-PROJECT-16H06145
[Journal Article] Characterization of the Human Transcription Elongation Factor Rtf1: Evidence for Non-overlapping Functions of Rtf1 and the Paf1 Complex.2015
- Author(s)
  Cao, Q. F., C., Yamamoto, J., Isobe, T., Tateno, S., Murase, Y., Chen, Y., Handa, H. and Yamaguchi, Y.
- Journal Title
  
  Mol Cell. Biol.
  
  Volume: 35 Issue: 20 Pages: 3459-3470
- DOI
  10.1128/mcb.00601-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23102002, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-26860318
[Journal Article] Binding of GID1 to DELLAs Promotes Dissociation of GAF1 from DELLA in GA Dependent Manner2015
- Author(s)
  Fukazawa, J., Ito, T., Yoshida, M., Kamiya, Y., Yamaguchi, S., and Takahashi, Y.
- Journal Title
  
  Plant Signaling and Behavior
  
  Volume: 10 Issue: 10 Pages: e1052923-e1052923
- DOI
  10.1080/15592324.2015.1052923
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26440148, KAKENHI-PROJECT-26650101, KAKENHI-PROJECT-15K18555, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118004, KAKENHI-PROJECT-15H04392
[Journal Article] CTCF regulates NELF, DSIF and P-TEFb recruitment during transcription.2015
- Author(s)
  Laitem, C., Zaborowska, J., Tellier, M., Yamaguchi, Y., Cao. Q.-F., Egloff, S., Handa, H., and Murphy, S.
- Journal Title
  
  Transcription
  
  Volume: 6 Pages: 79-90
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24118001
[Journal Article] SV40 VP1 major capsid protein in its self-assembled form allows VP1 pentamers to coat various types of artificial beads in vitro regardless of their sizes and shapes2015
- Author(s)
  M.-A. Kawano, K. Doi, H. Fukuda, Y. Kita, K. Imai, T. Inoue, T. Enomoto, M. Matsui, M. Hatakeyama, Y. Yamaguchi, H. Handa
- Journal Title
  
  Biotechnol. Rep.
  
  Volume: 5 Pages: 105-111
- DOI
  10.1016/j.btre.2014.12.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23102002, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-24241043, KAKENHI-PROJECT-26860112
[Journal Article] CTCF regulates NELF, DSIF and P-TEFb recruitment during transcription2015
- Author(s)
  Laitem, C., Zaborowska, J., Tellier, M., Yamaguchi, Y., Cao. Q.-F., Egloff, S., Handa, H., and Murphy, S.
- Journal Title
  
  Transcription
  
  Volume: 6 Pages: 79-90
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24118002
[Journal Article] Molecular role of RNF43 in canonical and noncanonical Wnt signaling2015
- Author(s)
  T. Tsukiyama,et al.
- Journal Title
  
  Mol. Cell. Biol.
  
  Volume: in press Issue: 11 Pages: 2007-2023
- DOI
  10.1128/mcb.00159-15
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25670184, KAKENHI-PUBLICLY-26115701, KAKENHI-PROJECT-26293041, KAKENHI-PROJECT-26860254, KAKENHI-PROJECT-15K15023, KAKENHI-PUBLICLY-15H01248, KAKENHI-PLANNED-24112006, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-25430102, KAKENHI-PROJECT-26670130
[Journal Article] An Aberrant Splice Acceptor Site Due to a Novel Intronic Nucleotide Substitution in MSX1 Gene Is the Cause of Congenital Tooth Agenesis in a Japanese Family2015
- Author(s)
  Tatematsu T, Kimura M, Nakashima M, Machida J, Yamaguchi S, Shibata A, Goto H, Nakayama A, Higashi Y, Miyachi H, Shimozato K, Matsumoto N, Tokita Y
- Journal Title
  
  Plos One
  
  Volume: 10(6) Issue: 6 Pages: e0128227-e0128227
- DOI
  10.1371/journal.pone.0128227
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118007
[Journal Article] DELLAs function as coactivators of GAI ASSOCIATED FACTOR1 in regulation of GA homeostasis and signaling in Arabidopsis2014
- Author(s)
  Fukazawa J, Teramura H, Murakoshi S, Nasuno K, Nishida N, Ito T, Yoshida M, Kamiya Y, Yamaguchi S, Takahashi Y.
- Journal Title
  
  Plant Cell
  
  Volume: 26 Issue: 7 Pages: 2920-2938
- DOI
  10.1105/tpc.114.125690
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-24118001, KAKENHI-PROJECT-26440148, KAKENHI-PROJECT-26650101, KAKENHI-PLANNED-24118004
[Journal Article] Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata2014
- Author(s)
  M. Takemoto, Y. Kawamura, M. Hirohama, Y. Yamaguchi, H. Handa, H. Saitoh, Y. Nakao, M. Kawada, K. Khalid, H. Koshino, K. Kimura, A. Ito, M. Yoshida
- Journal Title
  
  J. Antibiot. (Tokyo)
  
  Volume: 67 Issue: 4 Pages: 335-338
- DOI
  10.1038/ja.2013.142
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23102002, KAKENHI-PROJECT-23510288, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002
[Journal Article] DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes2014
- Author(s)
  J. Yamamoto, Y. Hagiwara, K. Chiba, T. Isobe, T. Narita, H. Handa, Y. Yamaguchi
- Journal Title
  
  Nat. Commun.
  
  Volume: 5 Issue: 1 Pages: 4263-4263
- DOI
  10.1038/ncomms5263
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23102002, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-24570156, KAKENHI-PROJECT-26860318
[Journal Article] Salicylic acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity2013
- Author(s)
  V. Gupta, S. Liu, H. Ando, R. Ishii, S. Tateno, Y. Kaneko, M. Yugami, S. Sakamoto, Y. Yamaguchi, O. Nureki, H. Handa
- Journal Title
  
  Mol. Pharmacol.
  
  Volume: 84 Issue: 6 Pages: 824-833
- DOI
  10.1124/mol.113.087940
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102002, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002
[Journal Article] Viral protein-coating of magnetic nanoparticles using simian virus 40 VP12013
- Author(s)
  T. Enomoto, M.-A. Kawano, H. Fukuda, W. Sawada, T. Inoue, K. C. Haw, Y. Kita, S. Sakamoto, Y. Yamaguchi, T. Imai, M. Hatakeyama, S. Saito, A. Sandhu, M. Matsui, I. Aoki, H. Handa
- Journal Title
  
  J. Biotechnol.
  
  Volume: 167 Issue: 1 Pages: 8-15
- DOI
  10.1016/j.jbiotec.2013.06.005
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23102002, KAKENHI-PROJECT-23590550, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-24241043, KAKENHI-PROJECT-24790169
[Journal Article] Vesnarinone Suppresses TNF α mRNA Expression by Inhibiting Valosin-containing Protein2013
- Author(s)
  Hotta K, Nashimoto A, Yasumura E, Suzuki M, Azuma M, Iizumi Y, Shima D, Nabeshima R, Hiramoto M, Okada A, Sakata-Sogawa K, Tokunaga M, Ito T, Ando H, Sakamoto S, Kabe Y, Aizawa S, Imai T, Yamaguchi Y, Watanabe H, Handa H
- Journal Title
  
  Mol Pharmacol
  
  Volume: Vol.83 Issue: 5 Pages: 930-938
- DOI
  10.1124/mol.112.081935
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20114004, KAKENHI-PLANNED-23102004, KAKENHI-PROJECT-23570172, KAKENHI-PROJECT-23689036, KAKENHI-PROJECT-23710267, KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-24650231, KAKENHI-PLANNED-23102002, KAKENHI-PLANNED-24118006
[Journal Article] Activation-induced cytidine deaminase auto-activates and triggers aberrant gene expression2013
- Author(s)
  Isobe, T., Song, S.-N. J., Tiwari, P., Ito, H., Yamaguchi, Y., and Yoshizaki, K.
- Journal Title
  
  FEBS Letters
  
  Volume: 587 Issue: 16 Pages: 2487-2492
- DOI
  10.1016/j.febslet.2013.06.028
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002
[Journal Article] Transcription elongation factors DSIF and NELF: promoter-proximal pausing and beyond2012
- Author(s)
  Yamaguchi, Y.
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1829 Issue: 1 Pages: 98-104
- DOI
  10.1016/j.bbagrm.2012.11.007
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24118001, KAKENHI-PLANNED-24118002
[Journal Article] ole of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway.2009
- Author(s)
  Kume K., Iizumi Y., Shimada M., Ito Y., Kishi T., Yamaguchi Y., Handa H.
- Journal Title
  
  Genes Cells 15
  
  Pages: 339-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052013
[Journal Article] Cellular dynamics of the negative transcription elongation factor NELF.2009
- Author(s)
  Yung T., Narita T., Komori T., Yamaguchi Y., Handa H.
- Journal Title
  
  Exp. Cell. Res. 315
  
  Pages: 1693-705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052013
[Journal Article] The role of human transcription elongation factor DSIF in the suppression of senescence and apoptosis.2009
- Author(s)
  Komori T., Inukai N., Yamada T., Yamaguchi Y., Handa H.
- Journal Title
  
  Genes Cells 14
  
  Pages: 343-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052013
[Journal Article] the Paf1 complex, and Tat-SF1 have non-redundant, cooperative roles in RNA polymerase II elongation.2009
- Author(s)
  Chen Y., Yamaguchi Y., Tsugeno Y, Yamamoto J., Yamada T, Nakamura M, Hisatake K., Handa H. DSIF
- Journal Title
  
  Genes & Dev. 23
  
  Pages: 2765-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052013
[Journal Article] Atrazine binds to FIF0-ATP synthase and inhibits mitochondrial function in sperm2008
- Author(s)
  Hase, Y., Tatsuno, M., Nishi, T., Kataoka, K., Kabe, Y., Yamaguchi, Y., Ozawa, N., Natori, M., Handa, H., Watanabe, H.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 366・1
  
  Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770148
[Journal Article] A new APE1/Ref-1-dependent pathway leading to reduction of NF-kB and AP-1, and activation of their DNA-binding activity.2008
- Author(s)
  Ando K. Hirao S., Kabe Y., Ogura Y. Sato I., Yamaguchi Y., Handa H.
- Journal Title
  
  Nucleic Acids Res. 36
  
  Pages: 4327-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20052013
[Journal Article] Evidence that SV40 VP1-DNA interactions contribute to the assembly of 40-nm spherical viral particles2007
- Author(s)
  Tsukamoto, H., Kawano, M., lnoue, T., Enomoto, T., Takahashi, R., Yokoyama, N., Yamamoto, N., Imai, T., Kataoka, K., Yamaguchi, Y., Handa, H.
- Journal Title
  
  Genes to Cells 12・11
  
  Pages: 1267-1279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770148
[Journal Article] DSIF contributes to transcriptional activation by DNA-binding activators by preventing pausing during transcription elongation2007
- Author(s)
  Zhu, W., Wada, T., Okabe, S., Taneda, T., Yamaguchi, Y., Handa, H.
- Journal Title
  
  Nucleic Acid Research 35・12
  
  Pages: 4064-4075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770148
[Journal Article] NELF interacts with CBC and participates in 3'-end processing of replication-dependent histone mRNAs2007
- Author(s)
  Narita, T., Yung, T.M.C., Yamamoto, J., Tsuboi, Y., Tanabe, H., Tanaka, K., Yamaguchi, Y., Handa, H.
- Journal Title
  
  Molecular Cell 26・3
  
  Pages: 349-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770148
[Journal Article] Hepatitis delta antigen binds to the clamp of RNA polymerase IIand affects transcriptional fidelity2007
- Author(s)
  Yamaguchi, Y., Mura, T., Chanarat, T., Okamoto, S., Handa, H.
- Journal Title
  
  Genes to Cells 12・7
  
  Pages: 863-875
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770148
[Journal Article] Hepatitis delta antigen binds to the clamp of RNA polymerase II and affect ranscriptional fidelity2007
- Author(s)
  Yamaguchi, Y., Mura, T., Chanarat, T., Okamoto, S., Handa, H.
- Journal Title
  
  Genes to Cells (in press)
- Data Source
  KAKENHI-PROJECT-18770148
[Journal Article] Differential regulation of NF-kB by elongation factors is determined by core promoter type2007
- Author(s)
  Amir-Zilberstein, L., Ainbinedr, E., Taube, L., Yamaguchi, Y., Handa, H., Dikstein, R.
- Journal Title
  
  Molecular and Cellular Biology 27・14
  
  Pages: 5246-5259
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18770148
[Journal Article] NELF interacts with CBC and participates in 3'-end processing of replication-dependent histone mRNAs2007
- Author(s)
  Narita, T., Yung, T.M.C., Yamamoto, J., Tsuboi, Y., Tanabe, H., Tanaka, K., Yamaguchi, Y., Hand, H.
- Journal Title
  
  Molecular Cell (in press)
- Data Source
  KAKENHI-PROJECT-18770148
[Journal Article] Knock-down of 25-kDa subunit of cleavage factor Im in HeLa cells alter alternative polyadenylation within 3' UTRs2006
- Author(s)
  Kubo, T., Wada, T., Yamaguchi, Y., Shimizu, A., Handa, H.
- Journal Title
  
  Nucleic Acid Research 34・21
  
  Pages: 6264-6271
- Data Source
  KAKENHI-PROJECT-18770148
[Journal Article] Transcriptional pausing caused by NELF plays a dual role in regulating immediate-early expression of the junB gene2006
- Author(s)
  Aida, M., Chen, Y., Nakajima, K., Yamaguchi Y., Wada, T., Handa, H.
- Journal Title
  
  Molecular and Cellular Biology 26・16
  
  Pages: 6094-6104
- Data Source
  KAKENHI-PROJECT-18770148
[Journal Article] TFII-I down-regulates a subset of estrogen-responsive genes through its interaction with an initiator element and estrogen receptor α2006
- Author(s)
  Ogura, Y., Azuma, M., Tsuboi, Y., Kabe, Y., Yamaguchi.Y., Wada, T., Watanabe, H., Handa, H.
- Journal Title
  
  Genes to Cells 11・4
  
  Pages: 373-381
- Data Source
  KAKENHI-PROJECT-18770148
[Patent] フェロトーシス抑制タンパク質1(FSP1)活性向上剤及びその用途、並びにFSP1活性向上剤をスクリーニングする方法2021
- Inventor(s)
  小坂仁、宮内彰彦、神保恵理子、小林瑞、山口雄輝
- Industrial Property Rights Holder
  小坂仁、宮内彰彦、神保恵理子、小林瑞、山口雄輝
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-185356
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20H03182
[Patent] 抗骨髄腫剤および抗骨髄腫剤のスクリーニング方法2020
- Inventor(s)
  半田宏、伊藤拓水、山口雄輝、日置(山本)淳一
- Industrial Property Rights Holder
  半田宏、伊藤拓水、山口雄輝、日置(山本)淳一
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-141689
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-20H03182
[Patent] p63スプライシングバリアントの分解剤およびその用途2019
- Inventor(s)
  半田宏、伊藤拓水、朝妻知子、ルイーザゲリーニ、山口雄輝
- Industrial Property Rights Holder
  東京医科大学、ミラノ大学、東京工業大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2019-139820
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17H06112
[Patent] CRBNモジュレーターの薬効を高める補助薬のスクリーニング方法2018
- Inventor(s)
  山口雄輝、舘野峻平、片山美樹、半田宏
- Industrial Property Rights Holder
  東京工業大学、東京医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-093652
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] Pol IIの一時停止および核体凝集体の制御におけるメディエーター複合体の役割2022
- Author(s)
  高橋秀尚, 鈴木秀文, 阿部竜太, 嶋田美穂, 廣瀬智威, 廣瀬博子, 野口慶介, 池陽子, 安井七海, 古郡華月, 山口雄輝, 豊田敦, 鈴木穣, 山本達郎, 斉藤典子, Sato Shigeo, Tomomori-Sato Chieri, Conaway Joan, Canaway Ronald
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] メディエーター複合体による新規の転写スピード調節機構の解明2022
- Author(s)
  鈴木秀文, 阿部竜太, 嶋田美穂, 廣瀬智威, 廣瀬博子, 野口慶介, 池陽子, 安井七海, 古郡華月, 山口雄輝, 豊田敦, 鈴木穣, 山本達郎, 斉藤典子, Sato Shigeo, Tomomori-Sato Chieri, Conaway Ronald, Conaway Joan, 高橋秀尚
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] レナリドマイド耐性多発性骨髄腫細胞の生存に重要なポマリドマイド依存性CRL4CRBNのネオ基質ARID2の解析2022
- Author(s)
  山本淳一, 山口雄輝, 半田宏
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] 二次元的スクリーニング解析を駆使した既存抗がん剤の新規作用機序の解明を目指した研究2022
- Author(s)
  原口大和, 坂本聡, 山口雄輝
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] 新規ビオチン標識法を用いたマルチオミクス解析によるCajal body構成因子の網羅的解析とCajal body形成メカニズムの解明2022
- Author(s)
  野口慶介, 鈴木秀文, 阿部竜太, 池陽子, 井野洋子, 木村弥生, 梁明秀, 土井宏, 田中章景, 山口雄輝, 高橋秀尚
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] ヒトRNAポリメラーゼと基本転写/修復因子TFIIHの新たな相互作用の構造生物学的研究2022
- Author(s)
  奥田昌彦, 諏訪哲史, 鈴木秀文, 山口雄輝, 西村善文
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] 新規ビオチン標識法を用いたマルチオミックス解析によるCajal body形成メカニズムの解明2021
- Author(s)
  野口慶介，鈴木秀文，阿部竜太，池陽子，井野洋子，木村弥生，梁明秀，土井宏，田中章景，山口雄輝，高橋秀尚
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] ナノ磁性ビーズ精製とCRISPRライブラリースクリーニングによる薬剤標的分子の網羅的同定を目指した研究2021
- Author(s)
  原口大和，坂本聡，山口雄輝
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] ポマリドミド依存的なCRBNのネオ基質ARID2の解析2021
- Author(s)
  山本淳一，山口雄輝，半田宏
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] メディエーター複合体による新規の3' Pol IIポージング制御機構の解明2021
- Author(s)
  鈴木秀文，阿部竜太，嶋田美穂，廣瀬智威，廣瀬博子，野口慶介，古郡華月，池陽子，安井七海，豊田敦，鈴木穣，山本達郎，斉藤典子，Ronald Conaway，Joan Conaway，山口雄輝，高橋秀尚
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] In situビオチン化によるコヒーシン近傍因子の探索2021
- Author(s)
  古屋智基，山口雄輝
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] 共通サブユニットRPB6を介したヒトRNAポリメラーゼIIと基本転写因子TFIIHの相互作用2021
- Author(s)
  諏訪哲史，奥田昌彦，鈴木秀文，西村善文，山口雄輝
- Organizer
  第44回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] RNAポリメラーゼと基本転写/修復因子TFIIHの新たな相互作用2021
- Author(s)
  奥田昌彦，諏訪哲史，山口雄輝，西村善文
- Organizer
  第39回染色体ワークショップ・第20回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] RNAポリメラーゼとTFIIHの相互作用部位の細胞機能解析2021
- Author(s)
  山口雄輝
- Organizer
  BINDS-NMR報告会
- Data Source
  KAKENHI-PROJECT-20H03182
[Presentation] E3ユビキチンリガーゼを標的とした創薬の新展開2019
- Author(s)
  山口雄輝
- Organizer
  東京工業大学　創薬ゲノムシンポジウム
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] 抗がん作用を有するカンナビノイドの作用機序の解析2019
- Author(s)
  小泉純玲、坂本聡、山口雄輝
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] In situでのビオチン化反応を利用したタンパク質間相互作用の解析2018
- Author(s)
  水止洋孝、新垣貴之、山口雄輝
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] Molecular mechanisms controlling pathways and sites for Pol Ⅱ transcription termination2018
- Author(s)
  Yuki Yamaguchi
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] TFIIH の多機能性を司るPleckstrin homology ドメインと新規標的因子の機能構造解析2018
- Author(s)
  諏訪哲史、鈴木秀文、奥田昌彦、西村善文、山口雄輝
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] Transcription silencing by TLP contributes to etoposide-induced apoptosis2017
- Author(s)
  Hidefumi Suzuki, Ryo Maeda, Hiroshi Kimura, Kiyoe Ura, Taka-aki Tamura, Yuki Yamaguchi
- Organizer
  Mechanisms of Eukaryotic Transcription 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] DNA損傷時に誘導される転写制御の生理的意義とTLPの役割2017
- Author(s)
  鈴木　秀文、前田　亮、木村　宏、浦　聖恵、山口　雄輝、田村　隆明
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] 多発性骨髄腫における Pomalidomide 標的因子の網羅的探索2017
- Author(s)
  舘野峻平、飯田緑、藤井聡、佐倉絵里、山口雄輝
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] E3ユビキチンリガーゼCRBNの細胞内局在が免疫調整薬IMiDsの薬効に及ぼす影響2017
- Author(s)
  徳山遥香、片山　美樹、山口　雄輝
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] メディエーター複合体による転写終結制御機構2017
- Author(s)
  高橋秀尚、柴田美音、瀧川一学、渡部昌、築山忠維、山本淳一、山口雄輝、藤井聡、飯田緑、Amol Ranjan、Shigeo Sato、Chieri Tomomori-Sato、Joan Conaway、Ronald Conaway、畠山鎮次
- Organizer
  ２０１７年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] 多発性骨髄腫における Pomalidomide 標的因子の網羅的探索2017
- Author(s)
  舘野峻平、飯田緑、藤井聡、佐倉絵里、山口雄輝
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] Mechanisms that affect post-transcriptional fate of RNA polymerase II-transcribed genes2017
- Author(s)
  Fajar Muhamad、Ari Zukeran、Shumpei Tateno、Junichi Yamamoto、Hiroshi Handa、Yuki Yamaguchi
- Organizer
  ２０１７年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] DNA損傷応答における転写抑制メカニズムとその生理的意義の解析2017
- Author(s)
  鈴木秀文、前田亮、木村宏、浦聖恵、田村隆明、山口雄輝
- Organizer
  ２０１７年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] NELFを中心としたポリ（A)付加部位の選択機構の解析2017
- Author(s)
  山本淳一、Fajar Muhamad、瑞慶覧安里、舘野俊平、半田宏、山口雄輝
- Organizer
  ConBio2017(生命科学系学会合同年次大会)
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] ターゲット因子の解析を基盤とする生物活性物質が示す作用機構の解明2017
- Author(s)
  坂本　聡、山口　雄輝、半田　宏
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] マウスES細胞における2細胞期特異的な遺伝子の発現制御メカニズムの解析2017
- Author(s)
  鈴木翔子、柴田紘孝、山口雄輝
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] E3ユビキチンリガーゼCRBNの細胞内局在が免疫調整薬IMiDsの薬効に及ぼす影響2017
- Author(s)
  徳山遥香、片山　美樹、山口　雄輝
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] Molecular mechanisms for polyadenylation site selection by NELF and related factors2017
- Author(s)
  Shumpei Tateno, Ari Zukeran, Junichi Yamamoto, Yuki Yamaguchi
- Organizer
  Mechanisms of Eukaryotic Transcription 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] DNA損傷時に誘導される転写制御の生理的意義とTLPの役割2017
- Author(s)
  鈴木　秀文、前田　亮、木村　宏、浦　聖恵、山口　雄輝、田村　隆明
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 遺伝情報の維持と制御の多層的理解に向けて2017
- Author(s)
  山口雄輝、林眞理
- Organizer
  ２０１７年度生命科学系学会合同年次大会（シンポジウムオーガナイザー）
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] ＲＮＡポリメラーゼⅡ転写産物の長さを決める３’末端プロセシングの制御メカニズムの解明2017
- Author(s)
  瑞慶覧安里、舘野　峻平、山本淳一、山口雄輝
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 抗炎症薬サリチル酸が示す生体内作用メカニズムの解析2017
- Author(s)
  坂本聡、Gupta Vipul、劉舒捷、安藤秀樹、舘野峻平、金子裕生、湯上真人、石井亮平、濡木理、山口雄輝、半田宏
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應義塾大学（神奈川県横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 抗炎症薬サリチル酸が示す生体内作用メカニズムの解析2017
- Author(s)
  坂本聡、Gupta Vipul、劉舒捷、安藤秀樹、舘野峻平、金子裕生、湯上真人、石井亮平、濡木理、山口雄輝、半田宏
- Organizer
  日本化学会第97春季年会
- Place of Presentation
  慶應義塾大学（神奈川県横浜市）
- Year and Date
  2017-03-16
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] マウスES細胞における2細胞期特異的な遺伝子の発現制御メカニズムの解析2017
- Author(s)
  鈴木翔子、柴田紘孝、山口雄輝
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] snRNAプロセシング因子Integrator複合体の分子構造解析2017
- Author(s)
  舘野峻平、Thiengtrong Benjarat、山口雄輝
- Organizer
  ２０１７年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] ターゲット因子の解析を基盤とする生物活性物質が示す作用機構の解明2017
- Author(s)
  坂本　聡、山口　雄輝、半田　宏
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] マウスES細胞における2細胞期特異的遺伝子Zscan4の転写制御機構の解明2017
- Author(s)
  鈴木翔子、柴田紘孝、山口雄輝
- Organizer
  ２０１７年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17H06112
[Presentation] ＲＮＡポリメラーゼⅡ転写産物の長さを決める３’末端プロセシングの制御メカニズムの解明2017
- Author(s)
  瑞慶覧安里、舘野　峻平、山本淳一、山口雄輝
- Organizer
  新学術領域研究「転写サイクル」冬の若手ワークショップ2017
- Place of Presentation
  一宮シーサイドオーツカ(千葉県一宮町)
- Year and Date
  2017-01-30
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] How Pol II termination and 3' processing sites are precisely determined in higher eukaryotes.高等真核生物においてPol IIの転写終結と3'プロセシングの部位はいかにして正確に決定されるのか2016
- Author(s)
  Ari Zukeran, Junichi Yamamoto, and Yuki Yamaguchi
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] マウスES細胞における2細胞期特異的な遺伝子の発現制御メカニズムの解析2016
- Author(s)
  鈴木翔子、柴田紘孝、山口雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] CRBNに対するサリドマイド光学異性体の結合基盤解析2016
- Author(s)
  坂本聡、伊藤拓水、森智行、安藤秀樹、山口雄輝、箱嶋敏雄、半田宏
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] サリドマイドの多様な薬理作用の分子メカニズム2016
- Author(s)
  山口雄輝、伊藤巧水、山本淳一、半田宏
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] PolⅡ複合体をモデルとしたタンパク質間相互作用の実験系の評価2016
- Author(s)
  新垣貴之、徳山遥香、山口雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] CRBNに対するサリドマイド光学異性体の結合基盤解析2016
- Author(s)
  坂本聡、伊藤拓水、森智行、安藤秀樹、山口雄輝、箱嶋敏雄、半田宏
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] NELFを中心としたポリ(A)付加部位選択のメカニズム2016
- Author(s)
  瑞慶覧安里、館野峻平、山本淳一、山口雄輝
- Organizer
  新学術領域研究「転写サイクル」班会議2016
- Place of Presentation
  松島一の坊（宮城県宮城郡）
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] 新規抗がん剤の作用機構の解明2016
- Author(s)
  佐倉絵里、舘野峻平、山口雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] PolⅡ複合体をモデルとしたタンパク質間相互作用の実験系の評価2016
- Author(s)
  新垣貴之、徳山遥香、山口雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] 高等真核生物においてPOL Ⅱの転写終結と3'プロセシングの部位はいかにして正確に決定されるのか2016
- Author(s)
  瑞慶覧安里、長谷川　冴妃子、館野　峻平、山本淳一、山口雄輝
- Organizer
  新学術領域研究「転写サイクル」班会議2016
- Place of Presentation
  松島一の坊（宮城県宮城郡）
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 転写産物とPolIIエンリッチメントプロファイリングによるDecapping exoribonuclease (Dom3z) の機能解析2016
- Author(s)
  飯田緑、磯部智康、山口雄輝、藤井聡
- Organizer
  転写サイクル合同班会議2016
- Place of Presentation
  松島一の坊(宮城県宮城郡)
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 高等真核生物においてPOL Ⅱの転写終結と3'プロセシングの部位はいかにして正確に決定されるのか2016
- Author(s)
  瑞慶覧安里、長谷川　冴妃子、館野　峻平、山本淳一、山口雄輝
- Organizer
  新学術領域研究「転写サイクル」班会議2016
- Place of Presentation
  松島一の坊（宮城県宮城郡）
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] リガンド依存的ユビキチンリガーゼＣＲＢＮの制御機構2016
- Author(s)
  伊藤拓水、朝妻知子、山本淳一　安藤秀樹、佐藤智美、山口雄輝、半田宏
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] snRNA3'末端プロセシング因子インテグレーターの構造・機能解析2016
- Author(s)
  外山　黛、荻原　裕里、Thiengtrong, Benjarat、山口　雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] ＴＢＰ類似因子ＴＬＰによるＤＮＡ損傷応答時の転写抑制と細胞死誘導機構の解析2016
- Author(s)
  鈴木秀文、前田亮、浦聖恵、木村宏、山口雄輝、田村隆明
- Organizer
  新学術領域研究「転写サイクル」班会議2016
- Place of Presentation
  松島一の坊（宮城県宮城郡）
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] リガンド依存的ユビキチンリガーゼＣＲＢＮの制御機構2016
- Author(s)
  伊藤拓水、朝妻知子、山本淳一　安藤秀樹、佐藤智美、山口雄輝、半田宏
- Organizer
  日本ケミカルバイオロジー学会第11回年会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] 新規抗がん剤の作用機構の解明2016
- Author(s)
  佐倉　絵里、舘野　峻平、山口　雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] Decapping exoribonuclease(DOX:Dom3z)の転写制御における機能解析2016
- Author(s)
  飯田緑、磯部智康、山口雄輝、藤井聡
- Organizer
  冬の若手ワークショップ2015
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-04
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 多発性骨髄腫におけるPomalidomide標的因子の網羅的探索2016
- Author(s)
  舘野峻平、飯田緑、藤井聡、山口雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] NELFを中心としたポリ(A)付加部位選択のメカニズム2016
- Author(s)
  瑞慶覧安里、山本淳一、山口雄輝
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] How Pol II termination and 3' processing sites are precisely determined in higher eukaryotes.高等真核生物においてPol IIの転写終結と3'プロセシングの部位はいかにして正確に決定されるのか2016
- Author(s)
  Ari Zukeran, Junichi Yamamoto, and Yuki Yamaguchi
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] サリドマイドの多様な薬理作用の分子メカニズム2016
- Author(s)
  山口雄輝、伊藤巧水、山本淳一、半田宏
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] ＴＢＰ類似因子ＴＬＰによるＤＮＡ損傷応答時の転写抑制と細胞死誘導機構の解析2016
- Author(s)
  鈴木秀文、前田亮、浦聖恵、木村宏、山口雄輝、田村隆明
- Organizer
  新学術領域研究「転写サイクル」班会議2016
- Place of Presentation
  松島一の坊（宮城県宮城郡）
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 多発性骨髄腫におけるPomalidomide標的因子の網羅的探索2016
- Author(s)
  舘野　峻平、飯田　緑、藤井　聡、山口　雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] サリドマイド標的タンパク質CRBNの相互作用因子の探索2016
- Author(s)
  徳山遥香、新垣貴之、山口雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] NELFを中心としたポリ(A)付加部位選択のメカニズム2016
- Author(s)
  瑞慶覧安里、館野峻平、山本淳一、山口雄輝
- Organizer
  新学術領域研究「転写サイクル」班会議2016
- Place of Presentation
  松島一の坊（宮城県宮城郡）
- Year and Date
  2016-09-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] NELFを中心としたポリ(A)付加部位選択のメカニズム2016
- Author(s)
  瑞慶覧安里、山本淳一、山口雄輝
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] Quantitative image analysis of dynamics of promoter-proximal pausing related proteins2016
- Author(s)
  國見慎之介, 伊藤由馬, 山口雄輝, 十川久美子, 徳永万喜洋
- Organizer
  第54回日本生物物理学会年会
- Place of Presentation
  つくば国際会議場（茨城県つくば市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] マウスES細胞における2細胞期特異的な遺伝子の発現制御メカニズムの解析2016
- Author(s)
  鈴木翔子、柴田紘孝、山口雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] snRNA3'末端プロセシング因子インテグレーターの構造・機能解析2016
- Author(s)
  外山黛、荻原裕里、Thiengtrong, Benjarat、山口雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] NELFを中心としたRNAの品質管理のメカニズム2016
- Author(s)
  瑞慶覧安里、山本淳一、磯部智康、山口雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] NELFを中心としたRNAの品質管理のメカニズム2016
- Author(s)
  瑞慶覧安里、山本淳一、磯部智康、山口雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] サリドマイド標的タンパク質CRBNの相互作用因子の探索2016
- Author(s)
  徳山遥香、新垣貴之、山口雄輝
- Organizer
  冬の若手ワークショップ2016
- Place of Presentation
  ホテル清渓（山梨県南都留郡）
- Year and Date
  2016-02-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] RNA polymerase IIのプロファイル解析2015
- Author(s)
  飯田緑、磯部智康、山口雄輝、藤井聡
- Organizer
  転写サイクル合同班会議2015
- Place of Presentation
  ホテル暖香園（静岡県伊東市）
- Year and Date
  2015-08-03
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 転写伸張因子DSIFのCTRを介した転写制御機構の解析2015
- Author(s)
  磯部智康、山口雄輝
- Organizer
  転写サイクル班会議2015
- Place of Presentation
  ホテル暖香園（静岡県伊東市）
- Year and Date
  2015-08-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] IMiDs標的タンパク質CRBNの生化学的解析2015
- Author(s)
  坂本聡、伊藤拓水、安藤秀樹、山口雄輝、半田宏
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 転写伸長段階の制御メカニズム：新たな制御因子の探索2015
- Author(s)
  山口雄輝、磯部智康、曹青福、山本淳一
- Organizer
  転写サイクル班会議2015
- Place of Presentation
  ホテル暖香園（静岡県伊東市）
- Year and Date
  2015-08-04
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] Regulatory Mechanisms for Pol II Termination Sites and 3' Processing Pathways in Higher Eukaryotes2015
- Author(s)
  Yuki Yamaguchi and Junichi Yamamoto
- Organizer
  MECHANISM OF EUKARYOTIC TRANSCRIPTION
- Place of Presentation
  Cold Spring Harbor(アメリカ）
- Year and Date
  2015-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] 転写伸張因子DSIFのCTRを介した転写制御機構の解析2015
- Author(s)
  磯部智康、山口雄輝
- Organizer
  転写サイクル班会議2015
- Place of Presentation
  ホテル暖香園（静岡県伊東市）ホテル暖香園
- Year and Date
  2015-08-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] IMiDs標的タンパク質CRBNの生化学的解析2015
- Author(s)
  坂本聡、伊藤拓水、安藤秀樹、山口雄輝、半田宏
- Organizer
  日本ケミカルバイオロジー学会第10回年会
- Place of Presentation
  東北大学（宮城県仙台市）
- Year and Date
  2015-06-10
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] Pol IIの転写伸長と運命決定制御のメカニズム2015
- Author(s)
  山口雄輝
- Organizer
  第２回北陸エピジェネティクス研究会
- Place of Presentation
  富山大学（富山県富山市）
- Year and Date
  2015-11-10
- Invited
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 多発性骨髄腫に対するポマリドマイドの標的因子の網羅的探索2015
- Author(s)
  館野俊平、飯田緑、藤井聡、山口雄輝
- Organizer
  第３８回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] ＰｏｌⅡの転写伸長と運命決定制御のメカニズム2015
- Author(s)
  山口雄輝
- Organizer
  第２回北陸エピジェネティクス研究会
- Place of Presentation
  富山大学（富山県富山市）
- Year and Date
  2015-11-10
- Invited
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] Elucidation of the molecular mechanisms of action of bioactive natural products using high performance affinity beads2015
- Author(s)
  Satoshi Sakamoto, Yuki Yamaguchi, Takumi Ito, Hiroshi Handa
- Organizer
  PACIFCHEM2015
- Place of Presentation
  ホノルル（アメリカ）
- Year and Date
  2015-12-17
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] NELFを中心としたmRNAの品質管理のメカニズム2015
- Author(s)
  瑞慶覧安里、山本淳一、磯部智康、山口雄輝
- Organizer
  転写サイクル班会議2015
- Place of Presentation
  ホテル暖香園（静岡県伊東市）
- Year and Date
  2015-08-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] Regulatory Mechanisms for Pol II Termination Sites and 3' Processing Pathways in Higher Eukaryotes2015
- Author(s)
  Yuki Yamaguchi and Junichi Yamamoto
- Organizer
  MECHANISM OF EUKARYOTIC TRANSCRIPTION
- Place of Presentation
  Cold Spring Harbor（アメリカ）
- Year and Date
  2015-08-27
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] アフィニティビーズを利用した生物活性物質標的タンパク質の単離・同定・評価2015
- Author(s)
  坂本　聡、山口雄輝、半田　宏
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（兵庫県神戸市）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 転写伸長因子DSIFのリン酸化の転写伸長反応への寄与の解析2015
- Author(s)
  磯部智康、千葉国俊、山口雄輝
- Organizer
  冬の若手ワークショップ2015
- Place of Presentation
  ホテル松本楼（群馬県渋川市）
- Year and Date
  2015-02-06
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] Biochemical analyses of CRBN, the target protein for immunomodulatory drugs (IMiDs)2015
- Author(s)
  Satoshi Sakamoto, ,Takumi Ito, Yuki Yamaguchi, Hideki Ando, Hiroshi Handa
- Organizer
  PACIFCHEM2015
- Place of Presentation
  ホノルル（アメリカ）
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] NELFを中心としたmRNAの品質管理のメカニズム2015
- Author(s)
  瑞慶覧安里、山本淳一、磯部智康、山口雄輝
- Organizer
  転写サイクル班会議2015
- Place of Presentation
  ホテル暖香園（静岡県伊東市）
- Year and Date
  2015-08-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes2015
- Author(s)
  山本　淳一、半田　宏、山口　雄輝
- Organizer
  冬の若手ワークショップ2015
- Place of Presentation
  ホテル松本楼（群馬県渋川市）
- Year and Date
  2015-02-06
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] Biochemical analyses of CRBN, the target protein for immunomodulatory drugs (IMiDs)2015
- Author(s)
  Satoshi Sakamoto, Takumi Ito, Yuki Yamaguchi, Hideki Ando, Hiroshi Handa
- Organizer
  PACIFCHEM2015
- Place of Presentation
  ホノルル（アメリカ）
- Year and Date
  2015-12-16
- Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] Elucidation of the molecular mechanisms of action of bioactive natural products using high performance affinity beads2015
- Author(s)
  Satoshi Sakamoto, Yuki Yamaguchi, Takumi Ito, Hiroshi Handa
- Organizer
  PACIFCHEM2015
- Place of Presentation
  ホノルル（アメリカ）
- Year and Date
  2015-12-17
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] 多発性骨髄腫に対するポマリドマイドの標的因子の網羅的探索2015
- Author(s)
  館野俊平、飯田緑、藤井聡、山口雄輝
- Organizer
  第３８回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] アフィニティビーズを利用した生物活性物質標的タンパク質の単離・同定・評価2015
- Author(s)
  坂本　聡、山口雄輝、半田　宏
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学（兵庫県神戸市）
- Year and Date
  2015-03-28
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] 転写伸長因子DSIFのリン酸化の転写伸長反応への寄与の解析2015
- Author(s)
  磯部智康、千葉国俊、山口雄輝
- Organizer
  冬の若手ワークショップ2015
- Place of Presentation
  ホテル松本楼（群馬県渋川市）
- Year and Date
  2015-02-06
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes2015
- Author(s)
  山本淳一、半田宏、山口雄輝
- Organizer
  冬の若手ワークショップ2015
- Place of Presentation
  ホテル松本楼（群馬県渋川市）
- Year and Date
  2015-02-06
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 転写伸長段階の制御メカニズム：新たな制御因子の探索2015
- Author(s)
  山口雄輝、磯部智康、曹青福、山本淳一
- Organizer
  転写サイクル班会議2015
- Place of Presentation
  ホテル暖香園（静岡県伊東市）
- Year and Date
  2015-08-04
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes2014
- Author(s)
  山本　淳一、半田　宏、山口　雄輝
- Organizer
  転写サイクル班会議2014
- Place of Presentation
  慶山（山梨県笛吹市）
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] 新規転写伸長因子ヒトRtf1が関与する転写制御の分子機構2014
- Author(s)
  曹　青福、陳　業熹、半田　宏、山口　雄輝
- Organizer
  転写サイクル班会議2014
- Place of Presentation
  慶山（山梨県笛吹市）
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] E3ユビキチンリガーゼの基質認識レセプター CRBNとポマリドマイド依存的な基質Aiolosの生化学的解析2014
- Author(s)
  片山美樹,伊藤拓水,安藤秀樹,山口雄輝,半田宏
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] 転写伸長因子DSIFおよびNELFがES細胞の多分化能維持に果たす役割2014
- Author(s)
  柴田　紘孝、半田　宏、山口　雄輝
- Organizer
  転写サイクル班会議2014
- Place of Presentation
  慶山（山梨県笛吹市）
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] Regulatory Mechanisms for Pol II Termination Sites and 3' Processing Pathways in Higher Eukaryotes2014
- Author(s)
  山口雄輝、山本淳一
- Organizer
  転写サイクル国際シンポジウム2014
- Place of Presentation
  東工大蔵前会館（東京都目黒区）
- Year and Date
  2014-11-24
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] 転写伸長因子DSIFにリン酸化依存的に相互作用する因子の機能解析2014
- Author(s)
  磯部智康、千葉国俊、山口雄輝
- Organizer
  転写サイクル班会議2014
- Place of Presentation
  慶山（山梨県笛吹市）
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] 抗炎症薬サリチル酸の生体内作用機構の解析2014
- Author(s)
  坂本聡、Vipul Gupta、劉舒捷、安藤秀樹、舘野峻平、金子裕生、湯上真人、石井亮平、濡木理、山口雄輝、半田宏
- Organizer
  日本ケミカルバイオロジー学会第９回年会
- Place of Presentation
  大阪大学（大阪府豊中市）
- Year and Date
  2014-06-11
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] p53非存在下でのATF3の機能2014
- Author(s)
  内田洋平, 川内潤也, 福本悟史, Paul Sheridan, 山口類, 井元清哉, 宮野悟, 北嶋繁孝
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-27
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] ヒトRNA ポリメラーゼII 転写産物のプロセシング経路の選択機構2014
- Author(s)
  山口雄輝、山本淳一、半田宏
- Organizer
  転写サイクル班会議2014
- Place of Presentation
  慶山（山梨県笛吹市）
- Year and Date
  2014-08-04
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] E3ユビキチンリガーゼの基質認識レセプター CRBNとポマリドマイド依存的な基質Aiolosの生化学的解析2014
- Author(s)
  片山美樹,伊藤拓水,安藤秀樹,山口雄輝,半田宏
- Organizer
  第３７回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] ヒトRNA ポリメラーゼII 転写産物のプロセシング経路の選択機構2014
- Author(s)
  山口雄輝、山本淳一、半田宏
- Organizer
  転写サイクル班会議2014
- Place of Presentation
  慶山（山梨県笛吹市）
- Year and Date
  2014-08-04
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] DSIF and NELF interact with Integrator to specify the correct post-transcriptional fate of snRNA genes2014
- Author(s)
  山本淳一、半田宏、山口雄輝
- Organizer
  転写サイクル班会議2014
- Place of Presentation
  慶山（山梨県笛吹市）
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] Regulatory Mechanisms for Pol II Termination Sites and 3' Processing Pathways in Higher Eukaryotes2014
- Author(s)
  山口雄輝、山本淳一
- Organizer
  転写サイクル国際シンポジウム2014
- Place of Presentation
  東工大蔵前会館（東京都目黒区）
- Year and Date
  2014-11-24
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 転写伸長因子DSIFおよびNELFがES細胞の多分化能維持に果たす役割2014
- Author(s)
  柴田　紘孝、半田　宏、山口　雄輝
- Organizer
  転写サイクル班会議2014
- Place of Presentation
  慶山（山梨県笛吹市）
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 転写伸長因子DSIFにリン酸化依存的に相互作用する因子の機能解析2014
- Author(s)
  磯部智康、千葉国俊、山口雄輝
- Organizer
  転写サイクル班会議2014
- Place of Presentation
  慶山（山梨県笛吹市）
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 抗炎症薬サリチル酸の生体内作用機構の解析2014
- Author(s)
  坂本聡、Vipul Gupta、劉舒捷、安藤秀樹、舘野峻平、金子裕生、湯上真人、石井亮平、濡木理、山口雄輝、半田宏
- Organizer
  日本ケミカルバイオロジー学会第9回年会
- Place of Presentation
  大阪大学（大阪市豊中市）
- Year and Date
  2014-06-11
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] Cellecta社製プール型レンチウイルスshRNAライブラリーを用いたスクリーニングデータ解析法の検討2014
- Author(s)
  飯田緑, 舘野峻平, 山口雄輝, 藤井聡
- Organizer
  冬の若手ワークショップ2014
- Place of Presentation
  舌切雀のお宿磯部ガーデン（群馬県）
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] 新規転写伸長因子ヒトRtf1が関与する転写制御の分子機構2014
- Author(s)
  曹　青福、陳　業熹、半田　宏、山口　雄輝
- Organizer
  転写サイクル班会議2014
- Place of Presentation
  慶山（山梨県笛吹市）
- Year and Date
  2014-08-05
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] DSIF and NELF interact with Integrator and participate in 3’ processing of snRNA genes: A possible mechanism controlling the fate of Pol II2013
- Author(s)
  Yamaguchi, Y., Yamamoto, J., and Handa, H.
- Organizer
  CSHL Meeting on Mechanisms of Eukaryotic Transcription
- Place of Presentation
  Cold Spring Harbor Laboratory（米国ニューヨーク州）
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] The mechanism of action of thalidomide, a drug with two faces2013
- Author(s)
  Yamaguchi, Y.
- Organizer
  International Marine Biotechnology Symposium 2013
- Place of Presentation
  沖縄産業支援センター（沖縄）
- Year and Date
  2013-03-18
- Invited
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] DSIF and NELF interact with Integrator and participate in 3’ processing of snRNA genes: A possible mechanism controlling the fate of Pol II2013
- Author(s)
  Yamaguchi, Y., Yamamoto, J., and Handa, H.
- Organizer
  CSHL Meeting on Mechanisms of Eukaryotic Transcription
- Place of Presentation
  Cold Spring Harbor Laboratory（米国ニューヨーク州）
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] The mechanism of action of thalidomide, a drug with two faces2013
- Author(s)
  Yamaguchi, Y.
- Organizer
  International Marine Biotechnology Symposium 2013
- Place of Presentation
  沖縄産業支援センター（沖縄）
- Year and Date
  2013-03-18
- Invited
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] The diverse pharmacological effects of thalidomide2013
- Author(s)
  Yamaguchi, Y.
- Organizer
  BioJapan 2013 World Business Forum
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Invited
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] The diverse pharmacological effects of thalidomide2013
- Author(s)
  Yamaguchi, Y.
- Organizer
  BioJapan 2013 World Business Forum
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Data Source
  KAKENHI-PLANNED-24118002
[Presentation] GAF1, a DELLA interacting protein, regulates gibberellin signaling in Arabidopsis2013
- Author(s)
  Fukazawa J, Fujiki T, Mori M, Miyamoto C, Kamiya Y, Yamaguchi S, Takahashi Y.
- Organizer
  21th International Plant Growth Substances Association Conference
- Place of Presentation
  中国・上海
- Data Source
  KAKENHI-ORGANIZER-24118001
[Presentation] Potential role of transcription elongation factors and elongation control in differentiation and maintenance of ES cells.2010
- Author(s)
  Yamaguchi Y.
- Organizer
  Japan-Israel Workshop on Stem Cells
- Place of Presentation
  Jerusalem, Israel
- Year and Date
  2010-02-25
- Data Source
  KAKENHI-PROJECT-20052013
[Presentation] Potential role of transcription elongation factors and elongation control in differentiation and maintenance of ES cells2010
- Author(s)
  Yuki Yamaguchi
- Organizer
  Japan-Israel Workshop on Stem Cells
- Place of Presentation
  Jerusalem, Israel
- Year and Date
  2010-02-25
- Data Source
  KAKENHI-PROJECT-20052013
[Presentation] DSIF, the Paf1 complex, and Tat-SF1 have non-redundant, cooperative roles in RNA polymerase II elongation.2009
- Author(s)
  Yamaguchi Y.
- Organizer
  CSHL Meeting on Mechanisms of Eukaryotic Transcription
- Place of Presentation
  New York, USA
- Year and Date
  2009-08-27
- Data Source
  KAKENHI-PROJECT-20052013
[Presentation] Mechanism of phosphorylation-dependent elongation activation by DSIF.2009
- Author(s)
  Yamaguchi Y
- Organizer
  EMBO Workshop on Messenger RNA 3' Ends & Gene Expression
- Place of Presentation
  Oxford, UK
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20052013
[Presentation] DSIF, the Paf1 complex, and Tat-SF1 have non-redundant, cooperative roles in RNA polymerase II elongation2009
- Author(s)
  Yuki Yamaguchi
- Organizer
  CSHL Meeting on Mechanisms of Eukaryotic Transcription
- Place of Presentation
  New York, USA
- Year and Date
  2009-08-27
- Data Source
  KAKENHI-PROJECT-20052013
[Presentation] Mechanism of phosphorylation-dependent elongation activation by DSIF2009
- Author(s)
  Yuki Yamaguchi
- Organizer
  EMBO Workshop on Messenger RNA 3' Ends & Gene Expression
- Place of Presentation
  Oxford, UK
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20052013
[Presentation] Multifaceted gene regulation by transcription elongation factors2008
- Author(s)
  Yamaguchi, Y.
- Organizer
  The 21st Naito Conference on Nuclear Dynamics〓d RNA [I]
- Place of Presentation
  Yamanashi, Japan
- Data Source
  KAKENHI-PROJECT-20052013
[Presentation] DSIF, the Paf1 complex, and Tat-SF1 have non-redundant, cooperative roles in RNA polymerase II elongation2008
- Author(s)
  Yamaguchi, Y., Chen, Y., Tsugeno, Y., Handa, H
- Organizer
  The 8th EMBL Transcription Meeting
- Place of Presentation
  Heidelberg, Germany
- Data Source
  KAKENHI-PROJECT-20052013
[Presentation] 転写伸長反応制御のメカニズム2008
- Author(s)
  山口雄輝
- Organizer
  第31回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20052013
[Presentation] DSIF, the Pafl complex, and Tat-SF1 have non-redundant, cooperative roles in RNA polymerase II elongation2008
- Author(s)
  Yamaguchi, Y., Chen, Y. Tsugeno, Y., and Handa, H.
- Organizer
  The 8th EMBL Transcription Meeting
- Place of Presentation
  Heidelberg, Germany
- Data Source
  KAKENHI-PROJECT-20052013
[Presentation] Multifaceted gene regulation by transcription elongation factors2008
- Author(s)
  Yamaguchi Y.
- Organizer
  The 21st Naito Conference on Nuclear Dynamics and RNA [I]
- Place of Presentation
  山梨
- Data Source
  KAKENHI-PROJECT-20052013
[]

1. HANDA Hiroshi (80107432)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. MURAKAMI Yota (20260622)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. NISHIYAMA Akira (80589664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAKABAYASHI Jun (80322733)

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5. Osaka Hitoshi (90426320)

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6. 和田忠士 (60262309)

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7. 濡木理 (10272460)

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8. 十川久美子 (20291073)

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9. 中村春木 (80134485)

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10. 松本直通 (80325638)

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11. 高橋陽介 (90183855)

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12. 緒方一博 (90260330)

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13. 伊藤敬 (90306275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
14. 田村智彦 (50285144)

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15. 高橋秀尚 (30423544)

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16. 川内潤也 (20544498)

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17. 柴田哲男 (40293302)

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# of Collaborated Products: 2 results
18. 北泰行 (00028862)

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19. 林由起子 (50238135)

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20. 秋山泰 (30243091)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. ISHI Shunsuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. TANAKA Kiyoji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. HIROSE Susumu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SHIOMI Haruhiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. SATO Fumitoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
26. ISOBE Tomoyasu

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
27. YAMAMOTO Junichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
28. KATO Junko

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. SUZUKI Hidefumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
30. SOU Seifuku

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
31. SHIBATA Hirotaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
32. TATENO Shumpei

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
33. HASEGAWA Sakiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
34. ARAKAKI Takayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
35. ZUKERAN Ari

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
36. KUROTAKI Daisuke

# of Collaborated Projects: 1 results

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37. BAN Tatsuma

# of Collaborated Projects: 1 results

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38. FUSHIMI Kentaro

# of Collaborated Projects: 1 results

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39. 嶋田美穂

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40. 朝妻知子

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41. 深澤壽太郎

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42. 徳永万喜洋

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43. 佐藤智美

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48. 加部泰明

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49. 百瀬修二

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Yamaguchi Yuuki 山口 雄輝

YAMAGUCHI Yuki 山口 雄輝

山口 雄輝 ヤマグチ ユウキ

Research Projects

Research Products

Co-Researchers

Structure-function analysis of transcription elongation/termination complexes using a new method capable of analyzing multifactor complexesPrincipal Investigator

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Elucidation of the selection mechanism of transcription termination and polyadenylation sites by using novel proteomic approachPrincipal Investigator

Principal Investigator

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Elucidation of the mechanism of mitochondrial disease cell death inhibition and drug discovery

Principal Investigator

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Review Section

Research Institution

Search for novel modulators of cereblon, the target of thalidomide that regulates neural stem cell proliferation and deifferentiation

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Promotion of the Transcription Cycle AreaPrincipal Investigator

Principal Investigator

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Elucidation of control mechanisms of transcriptional checkpoint during Pol II elongation, termination, and recyclePrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

Integral understanding of the mechanism of transcription cycle through quantitative, high-resolution approachesArea Organizer

Area Organizer

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Regulation of fate-determination of RNA and role of transcriptional machinery in heterochromatin formatin

Principal Investigator

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生細胞内(insitu)でタンパク質間の相互作用を解析・同定する新規な方法の開発Principal Investigator

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遺伝情報発現を転写伸長段階で制御するDECODE複合体の機能・構造解析

Principal Investigator

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ノックアウトマウスを用いた基本転写伸長因子の生理機能の解明Principal Investigator

Principal Investigator

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[Book] 遺伝子発現制御機構 クロマチン，転写制御，エピジェネティクス2017

Author(s)

Total Pages

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Data Source

[Book] 遺伝子発現制御機構 クロマチン，転写制御，エピジェネティクス2017

Author(s)

Total Pages

Publisher

Data Source

Yamaguchi Yuuki 山口雄輝

YAMAGUCHI Yuki 山口雄輝

山口雄輝ヤマグチユウキ

[Book] 遺伝子発現制御機構クロマチン，転写制御，エピジェネティクス2017

[Book] 遺伝子発現制御機構クロマチン，転写制御，エピジェネティクス2017