Masaki Okamoto 岡元昌樹

… Alternative Names

岡元昌樹オカモトマサキ

MASAKI Okamoto 岡元昌樹

OKAMOTO Masaki 岡元昌樹

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Researcher Number	50352133
Affiliation (Current)	2025: 久留米大学, 医学部, 准教授 2025: 独立行政法人国立病院機構九州医療センター(臨床研究センター), その他部局等, 呼吸器内科医長
Affiliation (based on the past Project Information) *help	2020 – 2023: 独立行政法人国立病院機構九州医療センター(臨床研究センター), その他部局等, 呼吸器内科医長 2016 – 2018: 久留米大学, 医学部, 講師 2013 – 2014: 久留米大学, 医学部, 講師 2007 – 2008: Kurume University, 医学部, 助教
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related / 膠原病・アレルギー・感染症内科学 Except Principal Investigator Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
Keywords	Principal Investigator ペリオスチン / 特発性肺線維症 / バイオマーカー / 間質性肺炎 / サンガーシークエンス / 遺伝子変異 / MDA5 / 急速進行性間質性肺疾患 / 皮膚筋炎 / コンパニオン診断薬 … More / 血清バイオマーカー / 特発性間質性肺炎 / ぺリオスチン / マウスモデル / 炎症 / サイトカイン … More Except Principal Investigator インジウム曝露 / 呼吸器症状 / KL-6 / 血清インジウム濃度 / 曝露 / 健康調査 / 歯科合金 / 健康影響 / 肺障害 / 歯科技工士 / インジウム Less

Analysis of MDA5 variant for predicting onset of rapid progressive interstitial lung disease with dermatomyositisPrincipal Investigator
- Principal Investigator
  
  岡元昌樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  National Hospital Organization, Kyushu Medical Center (Clinical Institute)
Health effects in dental technicians exposed dental indium alloy
- Principal Investigator
  
  Hirata Miyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  Kyushu University
The study of periositin, a new biomarker of idiopathic pulmonary fibrosisPrincipal Investigator
- Principal Investigator
  
  Masaki Okamoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kurume University
Development of new biomarker of interstitial pneumonia and drug-induced lung diseasePrincipal Investigator
- Principal Investigator
  
  MASAKI Okamoto
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kurume University
Roles of proinflammatory cytokine (IL-18) in idiopathic pulmonary fibrosisPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Masaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kurume University

All 2020 2019 2018 2017 2015 2014 2013 2009 2008 2007 Other

All Journal Article Presentation Book

[Book] バイオマーカー; ペリオスチンの可能性2017
- Author(s)
  岡元　昌樹
- Total Pages
  7
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-16K09567
[Journal Article] Indium kinetics in an indium exposed worker before and after bilateral lung transplantation2020
- Author(s)
  Nakano Makiko、Hirata Miyuki、Hamasaki Makoto、Tanaka Akiyo、Nagata Asahi、Kumazoe Hiroyuki、Wakamatsu Kentaro、Shiraishi Takeshi、Omae Kazuyuki
- Journal Title
  
  Journal of Occupational Health
  
  Volume: 62 Issue: 1 Pages: n/a
- DOI
  10.1002/1348-9585.12165
- NAID
  130007942414
- ISSN
  1341-9145, 1348-9585
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10663, KAKENHI-PROJECT-19H03906
[Journal Article] Ability of Periostin as a New Biomarker of Idiopathic Pulmonary Fibrosis.2019
- Author(s)
  Okamoto M, Izuhara K, Ohta S, Ono J, Hoshino T.
- Journal Title
  
  Adv Exp Med Biol
  
  Volume: 1132 Pages: 79-87
- DOI
  10.1007/978-981-13-6657-4_9
- ISBN
  9789811366567, 9789811366574
- Data Source
  KAKENHI-PROJECT-16K09567
[Journal Article] Low positive titer of anti-melanoma differentiation-associated gene 5 antibody is not associated with a poor long-term outcome of interstitial lung disease in patients with dermatomyositis.2018
- Author(s)
  Sakamoto S, Okamoto M, Kaieda S, Fujimoto K, Nagata S, Tominaga M, Nakamura M, Zaizen Y, Nouno T, Koga T, Kawayama T, Kuwana M, Ida H, Hoshino T.
- Journal Title
  
  Respir Investig
  
  Volume: 56 Issue: 6 Pages: 464-472
- DOI
  10.1016/j.resinv.2018.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09567, KAKENHI-PROJECT-16K09912
[Journal Article] The usefulness of monomeric periostin as a biomarker for idiopathic pulmonary fibrosis2017
- Author(s)
  Ohta S, Okamoto M, Fujimoto K, Sakamoto N, Takahashi K, Yamamoto H, Kushima H, Ishii H, Akasaka K, Ono J, Kamei A, Azuma Y, Matsumoto H, Yamaguchi Y, Aihara M, Johkoh T, Kawaguchi A, Ichiki M, Sagara H, Kadota JI, Hanaoka M, Hayashi SI, Kohno S, Hoshino T, Izuhara K
- Journal Title
  
  PloS one
  
  Volume: 12 Issue: 3 Pages: e0174547-e0174547
- DOI
  10.1371/journal.pone.0174547
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09595, KAKENHI-PROJECT-16K10168, KAKENHI-PROJECT-15K09553, KAKENHI-PROJECT-16K09535, KAKENHI-PROJECT-16K09567, KAKENHI-PROJECT-17K09618
[Journal Article] Serum level of periostin can predict long-term outcome of idiopathic pulmonary fibrosis.2015
- Author(s)
  Tajiri M, Okamoto M, et al.
- Journal Title
  
  The Respiratory Investigation
  
  Volume: 53 Pages: 73-81
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860663
[Journal Article] 特集「間質性肺炎とアレルギー」　各論　特発性間質性肺炎とサイトカイン2014
- Author(s)
  岡元　昌樹、星野　友昭
- Journal Title
  
  アレルギーの臨床
  
  Volume: 33 Pages: 17-22
- Data Source
  KAKENHI-PROJECT-25860663
[Journal Article] The progression of comorbidity in IL-18 transgenic chronic obstructive pulmonary disease mice model.2014
- Author(s)
  Takenaka S, Kawayama T, Imaoka H, Sakazakia Y, Oda H, Kaku Y, MatsuokaM, Okamoto M, Kato S, Yamada K, Hoshino T.
- Journal Title
  
  BBRC
  
  Volume: 445 Pages: 597-601
- Data Source
  KAKENHI-PROJECT-25860663
[Journal Article] Interleukin-18 expression, CD8+ T cells, and eosinophils in lungs of nonsmokers with fatal asthma.2014
- Author(s)
  Oda H, Kawayama T, Imaoka H, Sakazaki Y, Kaku Y, Okamoto M, Kitasato Y, Edakuni N, Takenaka S, Yoshida M, Iwanaga T, Kato S, O'Byrne PM, Hoshino T.
- Journal Title
  
  Asthma Immunol
  
  Volume: 112 Pages: 23-28
- Data Source
  KAKENHI-PROJECT-25860663
[Journal Article] IL-18 induces airway hyperresponsiveness and pulmonary inflammation via CD4+ T cell and IL-13.2013
- Author(s)
  Sawada M, Kawayama T, Imaoka H, Sakazaki Y, Oda H, Takenaka S, Kaku Y, Azuma K, Tajiri, M, Edakuni N, Okamoto M, Kato S, Hoshino T.
- Journal Title
  
  PLos One
  
  Volume: 8
- Data Source
  KAKENHI-PROJECT-25860663
[Journal Article] Role of Proinflammatory Cytokine IL-18 and IL-1{beta} in Bleomycin-induced Luna Injury in Humans and Mice2009
- Author(s)
  Hoshino T, Okamoto M, 他
- Journal Title
  
  Am J Respir Cell Mol Biol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] Role of proinflammatory cytokine il-18 and il-1{beta} in bleomycin-induced lung injury in humans and mice.2009
- Author(s)
  Hoshino T, Okamoto M, Sakazaki Y, Kato S, Young HA, Aizawa H.
- Journal Title
  
  Am J Respir Cell Mol Biol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] 特発性間質性肺炎における細胞外マトリクス分子periostin発現解析の意義.2008
- Author(s)
  太田昭一郎,岡元昌樹,内田賢,星野友昭,白石裕士,大島孝一,相澤久道,出原賢治.
- Journal Title
  
  臨床病理 56(補冊)
  
  Pages: 151-151
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] Interleukin-18 production and pulmonary function in copd.2008
- Author(s)
  Imaoka H, Hoshino T, Takei S, Kinoshita T, Okamoto M, Kawayama T, Kato S, Iwasaki H, Watanabe K, Aizawa H.
- Journal Title
  
  Eur Respir J 31(2)
  
  Pages: 287-297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] High levels of serum IL-18 promote cartilage loss through suppression of aaarecan synthesis2008
- Author(s)
  Inoue H, Okamoto M, 他
- Journal Title
  
  Bone 42
  
  Pages: 1102-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] High levels of serum il-18 promote cartilage loss through suppression of aggrecan synthesis.2008
- Author(s)
  Inoue H, Hiraoka K, Hoshino T, Okamoto M, Iwanaga T, Zenmyo M, Shoda T, Aizawa H, Nagata K.
- Journal Title
  
  Bone 42(6)
  
  Pages: 1102-1110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] 当院における間質性肺炎合併肺癌における予後と治療についての検討.2008
- Author(s)
  木下隆,東公一,岡元昌樹,今村陽平,池田二郎,藤本公則,相澤久道.
- Journal Title
  
  肺癌 48(5)
  
  Pages: 635-635
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] 血清il-18値は、進行性非小細胞癌における予後予測因子である.2008
- Author(s)
  岡元昌樹,東公一,星野友昭,池田二郎,戸田玲子,今岡治樹,木下隆,岩永知秋,相澤久道.
- Journal Title
  
  日本呼吸器学会雑誌 46(増刊)
  
  Pages: 299-299
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] 喘息死患者の肺病変部におけるil-18の発現.2008
- Author(s)
  坂崎優樹,星野友昭,武井仁子,今岡治樹,木下隆,岡元昌樹,川山智隆,岩永知秋,相澤久道.
- Journal Title
  
  日本呼吸器学会雑誌 46(増刊)
  
  Pages: 145-145
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] 特発性肺線維症と非特異性間質性肺炎におけるレドックス活性蛋白thioredoxin 1の発現の検討.2008
- Author(s)
  岩田安弘,岡元昌樹,星野友昭,北里裕彦,岩永知秋,相澤久道.
- Journal Title
  
  日本呼吸器学会雑誌 46(増刊)
  
  Pages: 274-274
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] シスプラチン、ドセタキセル、放射線同時併用療法を行った局所進行非小細胞肺癌患者におけるercc1, tubulinの発現と無増悪および全生存期間の検討.2008
- Author(s)
  東公一,岡元昌樹,木下隆,池田二郎,相澤久道.
- Journal Title
  
  日本呼吸器学会雑誌 46(増刊)
  
  Pages: 292-292
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] 当院における間質性肺炎合併肺癌の予後と治療についての検討.2008
- Author(s)
  木下隆,東公一,岡元昌樹,池田二郎,星野友昭,岩永知秋,相澤久道.
- Journal Title
  
  日本呼吸器学会雑誌 46(増刊)
  
  Pages: 208-208
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] Interleukin-18 production and pulmonary function in COPD2008
- Author(s)
  lmaoka H, Okamoto M, 他
- Journal Title
  
  Eur Respir J 31
  
  Pages: 287-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] Interleukin-18 production and pulmonary function in COPD2008
- Author(s)
  Imaoka H, Okamoto M, 他
- Journal Title
  
  Eur Respir J 31
  
  Pages: 287-297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] 喘息死患者の肺病変部におけるt細胞サブセットとサイトカイン発現の解析.2008
- Author(s)
  坂崎優樹,星野友昭,武井仁子,今岡治樹,木下隆,岡元昌樹,川山智隆,岩永知秋,相澤久道.
- Journal Title
  
  アレルギー 57(3-4)
  
  Pages: 443-443
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] Redox-regulated mechanisms in asthma.2008
- Author(s)
  Hoshino T, Okamoto M, Takei S, Sakazaki Y, Iwanaga T, Aizawa H.
- Journal Title
  
  Antioxid Redox Signal 10(4)
  
  Pages: 769-783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] Effects of thioredoxin on established airway remodeling in a chronic antigen exposure asthma model.2007
- Author(s)
  Imaoka H, Hoshino T, Takei S, Sakazaki Y, Kinoshita T, Okamoto M, Kawayama T, Yodoi J, Kato S, Iwanaga T, et al.
- Journal Title
  
  Biochem Biophys Res Commun 360(3)
  
  Pages: 525-530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] Thioredoxin prevents the development and progression of elastase-induced emphysema.2007
- Author(s)
  Kinoshita T, Hoshino T, Imaoka H, Ichiki H, Okamoto M, Kawayama T, Yodoi J, Kato S, Aizawa H.
- Journal Title
  
  Biochem Biophys Res Commun 354(3)
  
  Pages: 712-719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790700
[Journal Article] Adult t-cell lymphoma/leukemia with angioimmunoblastic t-cell lymphomalike features: Report of 11 cases.2007
- Author(s)
  Karube K, Suzumiya J, Okamoto M, Takeshita M, Maeda K, Sakaguchi M, Inada T, Tsushima H, Kikuchi M, Ohshima K.
- Journal Title
  
  Am J Surg Pathol 31(2)
  
  Pages: 216-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790700
[Presentation] 先端医学研究シンポジウム「間質性肺炎急性増悪の病態および新規治療」　IPF急性増悪、抗MDA5抗体陽性ILDの病態2019
- Author(s)
  岡元　昌樹
- Organizer
  第59回日本呼吸器学会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09567
[Presentation] シンポジウム「診断UP TO DATE～より的確な治療にむけて～」びまん性肺疾患のバイオマーカー2018
- Author(s)
  岡元　昌樹
- Organizer
  第81回日本呼吸器学会九州地方会秋季学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09567
[Presentation] 新規Periostin ELISAシステムを用いた肺線維症特異的バイオマーカーの探索研究2017
- Author(s)
  岡元　昌樹
- Organizer
  第57回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K09567
[Presentation] 新規Periostin ELISAシステムを用いた肺線維症特異的バイオマーカーの探索研究2017
- Author(s)
  岡元　昌樹, 他
- Organizer
  第57回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-16K09567
[Presentation] 血清ペリオスチン値は、IPFの長期予後因子である2014
- Author(s)
  岡元　昌樹，藤本　公則, 上甲　　剛，田尻　守拡, 小野　純也, 太田　昭一郎，出原　賢治，星野　友昭
- Organizer
  第54回日本呼吸器学会学術講演会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-25860663
[Presentation] 特発性肺線維症の新規血清バイオマーカーの解析2014
- Author(s)
  岡元　昌樹、藤本　公則、上甲　剛、田尻　守拡、小野　純也、太田　昭一郎、出原　賢治、星野　友昭
- Organizer
  第111回日本内科学会講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25860663
[Presentation] 特発性肺線維症の新規血清バイオマーカーの解析
- Author(s)
  岡元　昌樹, 他
- Organizer
  日本内科学会講演会
- Place of Presentation
  東京
- Year and Date
  2014-04-11 – 2014-04-13
- Data Source
  KAKENHI-PROJECT-25860663
[Presentation] 細胞外マトリックス蛋白；ペリオスチンの特発性肺線維症のバイオマーカーとしての解析
- Author(s)
  岡元　　昌樹, 他
- Organizer
  日本呼吸器学会学術講演会
- Place of Presentation
  大阪
- Year and Date
  2014-04-25 – 2014-04-27
- Data Source
  KAKENHI-PROJECT-25860663
[Presentation] Serum level of periostin can predict long-term outcome of idiopathic pulmonary fibrosis.
- Author(s)
  Tajiri M, Okamoto M, et al.
- Organizer
  European Respiratory Society Annual Congress
- Place of Presentation
  Munich, Germany
- Year and Date
  2014-09-06 – 2014-09-10
- Data Source
  KAKENHI-PROJECT-25860663

1. HOSHINO Tomoaki (00261066)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
2. Hirata Miyuki (30156674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 中野真規子 (70384906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 宮内博幸 (90784025)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山下喜久 (20192403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 田中昭代 (10136484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Masaki Okamoto 岡元 昌樹

岡元 昌樹 オカモト マサキ

MASAKI Okamoto 岡元 昌樹

OKAMOTO Masaki 岡元 昌樹

Research Projects

Research Products

Co-Researchers

Analysis of MDA5 variant for predicting onset of rapid progressive interstitial lung disease with dermatomyositisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Health effects in dental technicians exposed dental indium alloy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of periositin, a new biomarker of idiopathic pulmonary fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new biomarker of interstitial pneumonia and drug-induced lung diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of proinflammatory cytokine (IL-18) in idiopathic pulmonary fibrosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] バイオマーカー; ペリオスチンの可能性2017

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Indium kinetics in an indium exposed worker before and after bilateral lung transplantation2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Ability of Periostin as a New Biomarker of Idiopathic Pulmonary Fibrosis.2019

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Low positive titer of anti-melanoma differentiation-associated gene 5 antibody is not associated with a poor long-term outcome of interstitial lung disease in patients with dermatomyositis.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The usefulness of monomeric periostin as a biomarker for idiopathic pulmonary fibrosis2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serum level of periostin can predict long-term outcome of idiopathic pulmonary fibrosis.2015

Author(s)

Journal Title

Data Source

[Journal Article] 特集「間質性肺炎とアレルギー」 各論 特発性間質性肺炎とサイトカイン2014

Author(s)

Journal Title

Data Source

[Journal Article] The progression of comorbidity in IL-18 transgenic chronic obstructive pulmonary disease mice model.2014

Author(s)

Journal Title

Data Source

[Journal Article] Interleukin-18 expression, CD8+ T cells, and eosinophils in lungs of nonsmokers with fatal asthma.2014

Author(s)

Masaki Okamoto 岡元昌樹

岡元昌樹オカモトマサキ

MASAKI Okamoto 岡元昌樹

OKAMOTO Masaki 岡元昌樹

[Journal Article] 特集「間質性肺炎とアレルギー」　各論　特発性間質性肺炎とサイトカイン2014