KOBAYASHI Yasuhiko 小林泰彦

Researcher Number	50354957
External Links
Affiliation (based on the past Project Information) *help	2017: 国立研究開発法人量子科学技術研究開発機構, 放射線生物応用研究部, 部長 2012: 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, 研究主席 2007: Japan Atomic Energy Agency, TIARA, Group Leader 2007: Japan Atomic Enemy Agency, Quantum Beam Science Directorate TAKASAKI, Group Leader 2007: 日本原子力研究開発機構, 高碕量子応用研究所, グループリーダー … More 2005 – 2007: 日本原子力研究開発機構, 量子ビーム応用研究部門・バイオ応用技術研究ユニット, マイクロビーム細胞照射研究グループリーダー 2006: 日本原子力研究開発機構, 量子ビーム応用研究部門, グループリーダー 2006: 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, グループリーダー 2005 – 2006: 独立行政法人日本原子力研究開発機構, 量子ビーム応用研究部門, 研究主幹 2005: 日本原子力研究開発機構, 量子ビーム応用研究部門, マイクロビーム細胞照射研究グループリーダー 2004: 特殊法人日本原子力研究所, 高崎研究所・イオンビーム生物応用研究部, バイオ技術研究グループリーダー Less
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals Except Principal Investigator Radiation science / Applied entomology / Risk sciences of radiation/Chemicals / Nuclear engineering
Keywords	Principal Investigator Ku / non-homologous end joining / track structure / DNA damage / bystander effect / apoptosis / high-LET radiation / heavy-ion microbeam / 非相同末端結合 / トラック構造 … More / DNA損傷 / バイスタンダー効果 / アポトーシス / 高LET放射線 / 重イオンマイクロビーム … More Except Principal Investigator バイスタンダー効果 / 放射線 / イメージング / DNA二本鎖切断 / エピジェネティック制御 / 感受性 / 増感剤 / 併用効果 / 増感 / HDACi / HDAC阻害剤 / ヒストン脱アセチル化酵素阻害剤 / エピジェネティック / 重粒子線治療 / 重粒子線 / wound healing / Knobbed mutant / epidermis / regeneration / hemopoietic organ / hemocytes / hemopoietic microbeam / Bombyx mori / 傷害修復 / 昆虫 / 障害修復 / 放射線障害 / Sf9細胞 / eIF2αキナーゼ / 創傷修復 / コブ突然変異 / 真皮細胞 / 再生 / 造血器官 / 血球 / 重イオンマイクロビーム / カイコ / strong magnetic field / bystander effect / ionizing radiation / DNA damage / checkpoint / mitochondria / cell cycle / apoptosis / マイクロビーム / 重イオン線 / 減数分裂 / 生殖 / G1停止 / 強磁場 / DNA損傷 / チェックポイント / ミトコンドリア / 細胞周期 / アポトーシス / OHラジカル / モンテカルロシミュレーション / 水酸化ラジカル / 初期活性種 / 過渡吸収 / 時間分解分光測定 / 水中化学反応 / トラック構造 / 重イオン Less

Epigenetic Modifier as a Potential Radiosensitizer for Heavy-ion Therapy on Malignancy
- Principal Investigator
  
  SAITO KATSUYO
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Takasaki University of Health and Welfare
Space and time-resolved analyses of radical reactions densely produced by heavy ion irradiation
- Principal Investigator
  
  TAGUCHI Mitsumasa
- Project Period (FY)
  2009 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nuclear engineering
- Research Institution
  Japan Atomic Energy Agency
Studies on cell damage, healing and regeneration mechanism in insects using heavy-ion microbeams
- Principal Investigator
  
  KIGUCHI Kenji
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Applied entomology
- Research Institution
  Shinshu University
Analysis of local DNA-damage induced by high-LET heavy ions and cellular radiation response using heavyion microbeamsPrincipal Investigator
- Principal Investigator
  
  KOBAYASHI Yasuhiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Japan Atomic Energy Agency
Study of effect of ionizing radiation on germline cells
- Principal Investigator
  
  HIGASHITANI Atsushi
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Tohoku University

All 2017 2016 2015 2012 2011 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Epigenetic Modifier as a Potential Radiosensitizer for Heavy-ion Therapy on Malignancy (IV)2017
- Author(s)
  K. Saito, T. Funayama, Y. Kobayashi, T. Murakami
- Journal Title
  
  QST Takasaki Annual Report 2015
  
  Volume: QST-M-2 Pages: 115-115
- Open Access
- Data Source
  KAKENHI-PROJECT-26670566
[Journal Article] Histone Deacetylase Inhibitors Sensitize Murine B16F10 Melanoma Cells to Carbon Ion Irradiation by Inducing G1 Phase Arrest2017
- Author(s)
  Saito Katsuyo、Funayama Tomoo、Yokota Yuichiro、Murakami Takashi、Kobayashi Yasuhiko
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 6 Pages: 844-851
- DOI
  10.1248/bpb.b16-01025
- NAID
  130005688082
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00552, KAKENHI-PROJECT-26670566
[Journal Article] Epigenetic Modifier as a Potential Radiosensitizer for Heavy-ion Therapy on Malignancy (III)2016
- Author(s)
  K. Saito, T. Funayama, Y. Kobayashi, T. Murakami
- Journal Title
  
  JAEA Takasaki Annu. Rep. 2014
  
  Volume: JAEA-Review 2015-022 Pages: 75-75
- Open Access
- Data Source
  KAKENHI-PROJECT-26670566
[Journal Article] 1）Epigenetic Modifier as a Potential Radiosensitizer for Heavy-ion Therapy on Malignancy (II)2015
- Author(s)
  K. Saito, T. Funayama, Y. Kobayashi, T. Murakami
- Journal Title
  
  JAEA Takasaki Annu. Rep. 2013
  
  Volume: JAEA-Review 2014-050 Pages: 83-83
- Data Source
  KAKENHI-PROJECT-26670566
[Journal Article] Micro-/nanofabrication of crosslinked poly (L-lactic acid) using electron beam nanoimprint lithography2012
- Author(s)
  S.Okubo, N.Nagasawa, A.Kobayashi, T.Gowa Oyama, M.Taguchi, A.Oshima, S.Tagawa, M.Washio
- Journal Title
  
  Applied Physics Express
  
  Volume: 5 Issue: 2 Pages: 027303-027303
- DOI
  10.1143/apex.5.027303
- NAID
  10030156072
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360470
[Journal Article] Monte Carlo simulation of radial distribution of DNA strand breaks induced by C and Ne ions2011
- Author(s)
  R.Watanabe, S.Wada, T.Funayama, Y.Kobayashi, K.Saito, Y.Furusawa
- Journal Title
  
  Radiation Protection Dosimetry
  
  Volume: 143 Pages: 186-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21360470
[Journal Article] Effect of energetic heavy-ion irradiation on gene expression in Caenorha bditis elegans2008
- Author(s)
  Higashitani A, Mori C, Kimura T, Ikenaga T, Takanami T, Sakashita T, Wada S, Hamada N, Kobayashi Y.
- Journal Title
  
  JAEA-Review 2007-60 060
  
  Pages: 112-112
- Data Source
  KAKENHI-PROJECT-16310033
[Journal Article] Heavy-ion microbeam system at JAEA-Takasaki for microbeam biology2008
- Author(s)
  Funayama, T., S., Wada, Y., Yokota, K., Fukamoto, T., Sakashita, M., Taguchi, T., Kanzaki, N., Hamada, M., Suzuki, Y., Furusawa, H., Watanabe, K., Kiguchi, K., Kobayashi
- Journal Title
  
  Journal of Radiation Research 49
  
  Pages: 71-82
- NAID
  110006570530
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380036
[Journal Article] Role of DNA-PKcs in the bystander effect after low- or high-LET irradiation2007
- Author(s)
  Yuichi Kanasugi, Nobuyuki Hamada, Seiichi Wada, Tomoo Funayama, Tetsuya Sakashita, Takehiko Kakizaki, Yasuhiko Kobayashi, Kaoru Takakura
- Journal Title
  
  International Journal of Radiation Biology 83(2)
  
  Pages: 73-80
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Effect on energetic heavy-ion irradiation on gene expression in Caenorhabdtis elegans.2007
- Author(s)
  Higashitani A, Mori C, Kimura T, Ikenaga T, Takanami T, Sakashita T, Wada S, Hamada N, Kobayashi Y.
- Journal Title
  
  JAEA-Reviews.
  
  Pages: 60-60
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310033
[Journal Article] Role of DNA-PKcs in the bystander effect after low- or high-LET irraciation2007
- Author(s)
  Yuichi Kanasugi, Nobuyuki Hamada, Seiichi Wada, Tomoo Funayama, Tetsuya Sakashita, Takehiko Kakizaki, Yasuhiko Kobayashi, Kaoru Takakura
- Journal Title
  
  International Journal of Radiation Biology 83(2)
  
  Pages: 73-80
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Development of the irradiation method for the first instar silkworm larvae using locally targeted heavy-ion microbeam2007
- Author(s)
  Fukamoto, K., K., Shirai, T., Sakata, T., Sakashita, T., Funayama, N., Hamada, S., Wada, T., Kakizaki, S., Shimura, Y., Kobayashi, K., Kiguchi
- Journal Title
  
  Journal of Radiation Research 48
  
  Pages: 247-253
- NAID
  110006278200
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380036
[Journal Article] Role of DNA-PKcs in the bystander effect after low-or high-LET irradiation.2007
- Author(s)
  Yuichi Kanasugi, Nobuyuki Hamada, Seiichi Wada, Tomoo Funayama, Tetsuya Sakashita, Takehiko Kakizaki, Yasuhiko Kobayashi, Kaoru Takakura
- Journal Title
  
  International Journal of Radiation Biology 83
  
  Pages: 73-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Killing of feline T-lymphocytes by gamma-rays and energetic carbon ions.2006
- Author(s)
  Takehiko Kakizaki, Nobuyuki Hamada, Tomoo Funayama, Tetsuya Sakashita, Seiichi Wada, Tsutomu Hohdatsu, Masahiro Natsuhori, Tadashi Sano, Yasuhiko Kobayashi, Nobuhiko Ito
- Journal Title
  
  The Journal of Veterinary Medical Science 68
  
  Pages: 1269-1273
- NAID
  110005716367
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Method for detecting DNA strand breaks in mammalian cells using the Deinococcus radiodurans PprA protein2006
- Author(s)
  Katsuya Satoh, Seiichi Wada, Masahiro Kikuchi, Tomoo Funayama, Issay Narumi, Yasuhiko Kobayashi
- Journal Title
  
  Mutation Research : Fundamental and Molecular Mechanisms of Mutagenesis (印刷中)
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Effects of Heavy-ion irradiation on the differentiatin of epidermal cells in the silkworm, bombys mori2006
- Author(s)
  Fukamoto K., K.Shirai, R.Kanekatsu, K.Kiguchi, Y.Kobayashi
- Journal Title
  
  J. Insect Biotechnol. Sericol. 75
  
  Pages: 107-114
- Data Source
  KAKENHI-PROJECT-17380036
[Journal Article] Cell cycle arrest and apoptosis in Caenorhabditis elegans germline cells following heavy-ion microbeam irradiation.2006
- Author(s)
  Sugimoto T, Dazai K, Sakashita T, Funayama T, Wada S, Hamada N, Kakizaki T, Kobayashi Y, Higashitani A.
- Journal Title
  
  International Journal of Radiation Biology 82
  
  Pages: 31-38
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16310033
[Journal Article] Distinct modes of cell death by ionizing radiation observed in two lines of feline T-lymphocytes.2006
- Author(s)
  Takehiko Kakizaki, Nobuyuki Hamada, Seiichi Wada, Tomoo Funayama, Tetsuya Sakashita, Tsutomu Hohdatsu, Tadashi Sano, Masahiro Natsuhori, Yasuhiko Kobayashi, Nobuhiko Ito
- Journal Title
  
  Journal of Radiation Research 47
  
  Pages: 237-243
- NAID
  110004850770
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Analysis of Cellular Effects and Local Damage Induced by High LET Heavy Ions.2006
- Author(s)
  Seiichi Wada, Nobuyuki Hamada, Tomoo Funayama, Tetsuya Sakashita, Takehiko Kakizaki, Yuichiro Yokota, Yoshihiro Hase, Yasuhiko Kobayashi
- Journal Title
  
  JAEA-Review 2006-042
  
  Pages: 99-99
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Contribution of circulating hemocytes to the regeneration of heavy ion beams (^<12>C^<5+>) irradiated hematopoietic organs in the silkworm, Bombyx mori, through the way of phagocytosis of injured cells after invasion2006
- Author(s)
  Ling E, Shirai K, Kanekatsu R, Kiguchi K, Kobayashi Y, Funayama T, Watanabe H
- Journal Title
  
  Dev.Comp.Immunol In press
- Data Source
  KAKENHI-PROJECT-17380036
[Journal Article] LET-Dependent Survival of Irradiated Normal Human Fibroblasts and Their Descendents2006
- Author(s)
  Nobuyuki Hamada, Tomoo Funayama, Seiichi Wada, Testuya Sakashita, Takehiko Kakizaki, Meinan Ni, Yasuhiko Kobayashi
- Journal Title
  
  Radiation Research 166
  
  Pages: 24-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Analysis of Cellular Effects and Local Damage Induced by High LET Heavy Ions2006
- Author(s)
  Seiichi Wada, Nobuyuki Hamada, Tomoo Funayama, Tetsuya Sakashita, Takehiko Kakizaki, Yuichiro Yokota, Yoshihiro Hase, Yasuhiko Kobayashi
- Journal Title
  
  JAEA-Review 2006-042
  
  Pages: 99-99
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Process of In Vitro Cyst Formation from the Implanted Larval integument in the Sweet Potato Homworm, Agrius convolvuli : A Simple Model for Studying Wound Healing2006
- Author(s)
  Fukamoto, K. K. Shirai, S. Sato, R. Kanekatsu, K. Kiguchi, Y. Kobayashi
- Journal Title
  
  Journal of Insect Biotechnology and Sericology 75
  
  Pages: 99-106
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380036
[Journal Article] Method for detecting DNA strand breaks in mammalian cells using the Deinococcus radiodurans PprA protein2006
- Author(s)
  Katsuya Satoh, Seiichi Wada, Masahiro Kikuchi, Tomoo Funayama, Issay Narumi, Yasuhiko Kobayashi
- Journal Title
  
  Mutation Research : Fundamental and Molecular Mechanisms of Mutagenesis 596
  
  Pages: 36-42
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Killing of Feline T-Lymphocytes by Gamma-Rays and Energetic Carbon Ions2006
- Author(s)
  Takehiko Kakizaki, Nobuyuki Hamada, Tomoo Funayama, Tetsuya Sakashita, Seiichi Wada, Tsutomu Hohdatsu, Masahiro Natsuhori, Tadashi Sano, Yasuhiko Kobayashi, Nobuhiko Ito
- Journal Title
  
  The Journal of Veterinary Medical Science 68(12)
  
  Pages: 1269-1273
- NAID
  110005716367
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Distinct Modes of Cell Death by Ionizing Radiation Observed in Two Lines of Feline T-Lymphocytes2006
- Author(s)
  Takehiko Kakizaki, Nobuyuki Hamada, Seiichi Wada, Tomoo Funayama, Tetsuya Sakashita, Tsutomu Hohdatsu, Tadashi Sano, Masahiro Natsuhori, Yasuhiko Kobayashi, Nobuhiko Ito
- Journal Title
  
  Journal of Radiation Research 47(3-4)
  
  Pages: 237-243
- NAID
  110004850770
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Method for detecting DNA strand breaks in mammalian cells using the Deinococcus radiodurans PprA protein.2006
- Author(s)
  Katsuya Satoh, Seiichi Wada, Masahiro Kikuchi, Tomoo Funayama, Issay Narumi, Yasuhiko Kobayashi
- Journal Title
  
  Mutation Research /Fundamental and MolecularMechanisms of Mutagenesis 596
  
  Pages: 36-42
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Cell cycle arrest and apoptosis in Caenorhabditis elegans germline cells following heavy-ion microbeam irradiation.2006
- Author(s)
  Sugimoto T, Dazai K, Sakashita T, Funayama T, Wada S, Hamada N, Kakizaki T, Kobayashi Y, Higashitani A
- Journal Title
  
  International J. Radiation Biology 82
  
  Pages: 31-38
- Data Source
  KAKENHI-PROJECT-16310033
[Journal Article] Cell cycle arrest and apoptosis in Caenorhabditis elegans germline cells following heavy-ion microbeam irradiation2006
- Author(s)
  Sugimoto T, Dazai K, Sakashita T, Funayama T, Wada S, Hamada N, Kakizaki T, Kobayashi Y, Higashitani A.
- Journal Title
  
  Intl. J. Radiat. Biol 82(1)
  
  Pages: 31-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16310033
[Journal Article] Effects of heavy-ion irradiation on the differentiation of epidermal cells in the silkworm, Bombyx mori2006
- Author(s)
  Fukamoto, K. S. Shimura, K. Shirai, R. Kanekatsu, K. Kiguchi, T. Sakashita, T. Funayama, Y. Kobayashi
- Journal Title
  
  Journal of Insect Biotechnology and Sericology 75
  
  Pages: 107-114
- NAID
  10020516340
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380036
[Journal Article] Construction of monitoring system for biological effects of local ionizing radiation using the nematode C. elegans.2006
- Author(s)
  Higashitani A, Sugimoto T, Mori C, Suzuki Y, Saito R, Ichiishi E, Sakashita T, Hamada N, Wada S, Kakizaki T, Funayama T, Kobayashi Y.
- Journal Title
  
  JAEA-Reviews.
  
  Pages: 42-42
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310033
[Journal Article] 細胞局部照射実験の歴史と粒子線マイクロビームのマイクロサージャリへの応用2006
- Author(s)
  小林泰彦
- Journal Title
  
  RADIOISOTOPES 55
  
  Pages: 281-292
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] LET Dependent Survival of Irradiated Normal Human Fibroblasts and Their Descendents2006
- Author(s)
  Nobuyuki Hamada, Tomoo Funayama, Seiichi Wada, Testuya Sakashita, Takehiko Kakizaki, Meinan Ni, Yasuhiko Kobayashi
- Journal Title
  
  Radiation Research (印刷中)
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Contribution of circulating hemocytes to the regeneration of heavy ion beams (12C5+) irradiated hematopoietic organs in the silkworm, Bombyx mori, through the way of phagocytosis of injured cells after invasion2006
- Author(s)
  Ling, E. K. Shirai, R. Kanekatsu, K. Kiguchi, Y. Kobayashi, T. Funayama, H. Watanabe
- Journal Title
  
  Developmental & Comparative Immunology 30
  
  Pages: 531-543
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380036
[Journal Article] Process of in vivo cyst formation from the implanted larval integumen in the sweet potato hornworm, Agrius convolvuli : a simple model for studying wound healing.2006
- Author(s)
  Fukamoto K., K.Shirai, R.Kanekatsu, K.Kiguchi, Y.Kobayashi
- Journal Title
  
  J. Insect Biotechnol Sericol. 75
  
  Pages: 99-106
- Data Source
  KAKENHI-PROJECT-17380036
[Journal Article] Cell cycle arrest and apoptosis in Caenorhabditis elegans germline cells following heavy-ion microbeam irradiation.2006
- Author(s)
  Sugimoto T, Dazai K, Sakashita T, Funayama T, Wada S, Hamada N, Kakizaki T, Kobayashi Y, Higashitani A.
- Journal Title
  
  International J.Radiation Biology 82
  
  Pages: 31-38
- Data Source
  KAKENHI-PROJECT-16310033
[Journal Article] LET dependent survival of irradiated normal human fibroblasts and their descendents.2006
- Author(s)
  Nobuyuki Hamada, Tomoo Funayama, Seiichi Wada, Testuya Sakashita, Takehiko Kakizaki, Meinan Ni, Yasuhiko Kobayashi
- Journal Title
  
  Radiation Research 166
  
  Pages: 24-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Prediction of Cellular Radiosensitivity from DNA Damage Induced by γ-Rays and Carbon Ion Irradiation in Canine Tumor Cells2005
- Author(s)
  Seiichi Wada, Tran Van Khoa, Yasuhiko Kobayashi, Tomoo Funayama, Kikumi Ogihara, Shunji Ueno, Nobuhiko Ito
- Journal Title
  
  Journal of Veterinary Medical Science 67(11)
  
  Pages: 1089-1095
- NAID
  110004049148
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Cellular Radiation Response and Local Damage Induced by High LET Heavy Ions2005
- Author(s)
  Seiichi Wada, Tomoo Funayama, Tetsuya Sakashita, Yuichiro Yokota, Nobuyuki Hamada, Takehiko Kakizaki, Yoshihiro Hase, Yasuhiko Kobayashi
- Journal Title
  
  JAEA-Review 2005-001
  
  Pages: 102-103
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Exploration of 'Over Kill Effect' of High-LET Ar- and Fe-ions by Evaluating the Fraction of Non-hit Cell and Interphase Death2005
- Author(s)
  Parinaz Mehnati, Shigeko Morimoto, Fumio Yatagai, Yoshiya Furusawa, Yasuhiko Kobayashi, Seiichi Wada, Tatsuaki Kanai, Fumio Hanaoka Hiroshi Sasaki
- Journal Title
  
  Journal of Radiation Research 46(3)
  
  Pages: 343-350
- NAID
  110004041134
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] マイクロビームによる細胞のピンポイント照射2005
- Author(s)
  小林泰彦
- Journal Title
  
  放射線と産業 181
  
  Pages: 21-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Prediction of Cellular Radiosensitivity from DNA Damage Induced by γ-Rays and Carbon Ion Irradiation in Canine Tumor Cells2005
- Author(s)
  Seiichi Wada, Tran Van Khoa, Yasuhiko Kobayashi, Tomoo Funayama, Kikumi Ogihara, Shunji Ueno, Nobuhiko Ito
- Journal Title
  
  Journal of Veterinary medical Science 67(11)
  
  Pages: 1089-1095
- NAID
  110004049148
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Prediction of cellular radiosensitivity from DNA damage induced by γ-rays and carbon ion irradiation in canine tumor cells.2005
- Author(s)
  Seiichi Wada, Tran Van Khoa, Yasuhiko Kobayashi, Tomoo Funayama, Kikumi Ogihara, Shunji Ueno, Nobuhiko Ito
- Journal Title
  
  Journal of Veterinary Medical Science 67
  
  Pages: 1089-1095
- NAID
  110004049148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Analysis of Cellular Radiation Response and Local Damage Induced by High LET Heavy Ions.2005
- Author(s)
  Seiichi Wada, Tomoo Funayama, Tetsuya Sakashita, Yuichiro Yokota, Nobuyuki Hamada, Takehiko Kakizaki, Yoshihiro Hase, Yasuhiko Kobayashi
- Journal Title
  
  JAEA-Review 2005-001
  
  Pages: 102-103
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Irradiation of mammalian cultured cells with collimated heavy ion microbeam.2005
- Author(s)
  Tomoo Funayama, Seiichi Wada, Yasuhiko Kobayashi, Hiroshi Watanabe
- Journal Title
  
  Radiation Research 163
  
  Pages: 241-256
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Journal Article] Effects of microbeam irradiation on G1 arrest and apoptosis in germ cells of Caenorhabditis elegans.2005
- Author(s)
  Higashitani A, Sugimoto T, Dazai K, Sakashita T, Funayama T, Wada S, Hamada N, Kakizaki T, Kobayashi Y.
- Journal Title
  
  JAEA-Reviews.
  
  Pages: 1-1
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310033
[Journal Article] Irradiation of mammalian cultured cells with collimated heavy ion microbeam2005
- Author(s)
  Tomoo Funayama, Seiichi Wada, Yasuhiko Kobayashi, Hiroshi Watanabe
- Journal Title
  
  Radiation Research 163(2)
  
  Pages: 241-246
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17510055
[Presentation] ヒストン脱アセチル化酵素阻害剤による重粒子線感受性の増強は、H2AXのリン酸化の増加に起因しない2017
- Author(s)
  斎藤克代、舟山知夫、横田裕一郎、小林泰彦、村上孝
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター等（宮城県）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-26670566
[Presentation] 難治性がんに対するエピジェネティック制御と重粒子線感受性の増強（IV）2017
- Author(s)
  斎藤克代、舟山知夫、横田裕一郎、小林泰彦、村上孝
- Organizer
  第1回QST高崎研シンポジウム
- Place of Presentation
  高崎量子応用研究所（群馬県）
- Year and Date
  2017-01-26
- Data Source
  KAKENHI-PROJECT-26670566
[Presentation] ヒストン脱アセチル化酵素阻害剤は重粒子線誘発G2/M期停止に影響を及ぼす2016
- Author(s)
  斎藤克代、舟山和夫、小林泰彦、村上孝
- Organizer
  日本薬学会136年会
- Place of Presentation
  パシフィコ横浜（神奈川県）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-26670566
[Presentation] 難治性がんに対するエピジェネティック制御と重粒子線感受性の増強（III）2015
- Author(s)
  斎藤克代、舟山知夫、小林泰彦、村上孝
- Organizer
  第10回高崎量子応用研究シンポジウム
- Place of Presentation
  高崎シティギャラリー（群馬県）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26670566
[Presentation] Epigenetic modification potentially sensitizes heavy-ion therapy for malignancy2015
- Author(s)
  Katsuyo Saito, Tomoo Funayama, Yasuhiko Kobayashi, Takashi Murakami
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  京都国際会館
- Year and Date
  2015-05-25
- Data Source
  KAKENHI-PROJECT-26670566
[Presentation] Histone deacetylase inhibitors potentially sensitize murine B16 melanoma cells to heavy-ion irradiation2015
- Author(s)
  Katsuyo Saito, Tomoo Funayama, Yasuhiko Kobayashi, Takashi Murakami
- Organizer
  日本放射線腫瘍学会第28回学術大会
- Place of Presentation
  ベイシア文化ホール（群馬県）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-26670566
[Presentation] Regeneration mechanism of hemopoietic organs in the silkworm, Bombyx mori, after heavy-ion irradiation : Analysis by transplantation of the irradiated organs using a transgenic silkworm strain2008
- Author(s)
  Shirai, K., Kiguchi, K., Sakata, T., Fukamoto, K., Sakashita, T., Funayama, T., Hamada, N., Kobayashi, Y
- Organizer
  Asia-Pacific Congress of Sericulture and Insect Biotechnology
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17380036
[Presentation] 重イオン照射造血器官の崩壊・再生機構-時期特異的マーカーの探索2007
- Author(s)
  小林智史, 他
- Organizer
  日本蚕糸学会中部支部・東海支部合同大会
- Place of Presentation
  ジョイントプラザマリオ
- Year and Date
  2007-11-28
- Data Source
  KAKENHI-PROJECT-17380036
[Presentation] 重イオン照射造血器官の崩壊・再生機構-時期特異的な分子マーカーの探索2007
- Author(s)
  小林智史, 他
- Organizer
  日本蚕糸学会中部支部
- Place of Presentation
  岡谷市
- Year and Date
  2007-11-29
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17380036
[Presentation] 重イオンマイクロビームを用いた線虫Cエレガンスの放射線応答の研究2006
- Author(s)
  東谷篤志、森ちひろ、杉本朋子、太斎久美子、坂下哲哉、舟山知夫、柿崎竹彦、浜田信行、和田成一、小林泰彦
- Organizer
  第49回日本放射線影響学会大会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310033
[Presentation] モデル生物線虫Cエレガンスの生殖細胞における放射線応答の研究2006
- Author(s)
  森ちひろ、池永敬彦、杉本朋子、太斎久美子、坂下哲哉、舟山知夫、柿崎竹彦、浜田信行、和田成一、小林泰彦、一石英一郎、斎藤るみ子、東谷篤志
- Organizer
  第49回日本放射線影響学会大会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310033
[Presentation] 重イオンマイクロビームによる放射線影響とバイスタンダー効果の研究2005
- Author(s)
  東谷篤志、杉本朋子、太斎久美子、坂下哲哉、舟山知夫、和田成一、柿崎竹彦、小林泰彦
- Organizer
  第14回 TIARA研究発表会
- Place of Presentation
  高崎市群馬県
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16310033
[Presentation] 1）エピジェネティック修飾を介した難治性がんに対する重粒子線感受性の増強
- Author(s)
  斎藤克代、舟山知夫、小林泰彦、村上孝
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸学院大学他（兵庫県）
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26670566
[Presentation] 難治性がんに対するエピジェネティック制御と重粒子線感受性の増強（Ⅱ）
- Author(s)
  斎藤克代、舟山知夫、小林泰彦、村上孝
- Organizer
  第9回高崎量子応用研究シンポジウム
- Place of Presentation
  高崎シティギャラリー（群馬県）
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-26670566

1. TAGUCHI Mitsumasa (60343943)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. KATSUMURA Yosuke (70111466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. WATANABE Ritsuko (10360439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. SUGO Yumi (90354836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KURASHIMA Satoshi (50370391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HIGASHITANI Atsushi (40212162)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. KIGUCHI Kenji (50262697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
8. SHIRAI Koji (00293499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
9. SHIDA Toshio (40162599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SATO Shigeru (10125073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. SAITO KATSUYO (90455288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
12. FUNAYAMA Tomoo (40354956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
13. YOKOTA Yuichiro (30391288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 村上孝 (00326852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results

KOBAYASHI Yasuhiko 小林 泰彦

Research Projects

Research Products

Co-Researchers

Epigenetic Modifier as a Potential Radiosensitizer for Heavy-ion Therapy on Malignancy

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Space and time-resolved analyses of radical reactions densely produced by heavy ion irradiation

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Studies on cell damage, healing and regeneration mechanism in insects using heavy-ion microbeams

Principal Investigator

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Analysis of local DNA-damage induced by high-LET heavy ions and cellular radiation response using heavyion microbeamsPrincipal Investigator

Principal Investigator

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Study of effect of ionizing radiation on germline cells

Principal Investigator

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Research Institution

[Journal Article] Epigenetic Modifier as a Potential Radiosensitizer for Heavy-ion Therapy on Malignancy (IV)2017

Author(s)

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Data Source

[Journal Article] Histone Deacetylase Inhibitors Sensitize Murine B16F10 Melanoma Cells to Carbon Ion Irradiation by Inducing G1 Phase Arrest2017

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[Journal Article] Epigenetic Modifier as a Potential Radiosensitizer for Heavy-ion Therapy on Malignancy (III)2016

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[Journal Article] 1）Epigenetic Modifier as a Potential Radiosensitizer for Heavy-ion Therapy on Malignancy (II)2015

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[Journal Article] Micro-/nanofabrication of crosslinked poly (L-lactic acid) using electron beam nanoimprint lithography2012

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[Journal Article] Monte Carlo simulation of radial distribution of DNA strand breaks induced by C and Ne ions2011

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[Journal Article] Effect of energetic heavy-ion irradiation on gene expression in Caenorha bditis elegans2008

Author(s)

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[Journal Article] Heavy-ion microbeam system at JAEA-Takasaki for microbeam biology2008

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[Journal Article] Role of DNA-PKcs in the bystander effect after low- or high-LET irradiation2007

Author(s)

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Data Source

[Journal Article] Effect on energetic heavy-ion irradiation on gene expression in Caenorhabdtis elegans.2007

KOBAYASHI Yasuhiko 小林泰彦