Kiyosue Kazuyuki 清末和之

… Alternative Names

清末和之キヨスエカズユキ

KIYOSUE Kazuyuki 清末和之

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Researcher Number	50356903
Other IDs	https://orcid.org/0000-0001-9439-3295
Affiliation (Current)	2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 特定技術担当主幹
Affiliation (based on the past Project Information) *help	2023: 国立研究開発法人産業技術総合研究所, 生命工学領域, 特定技術担当主幹 2019 – 2022: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究グループ長 2014: 独立行政法人産業技術総合研究所, バイオメディカル研究部門, グループリーダー 2012 – 2013: 独立行政法人産業技術総合研究所, 健康工学研究部門, 主任研究員 2010: National Institute of Advanced Industrial Science and Technology, バイオメディカル研究部門, 研究グループ付 … More 2010: 産業技術総合研究所, 脳神経情報部門, 主任研究員 2008 – 2009: National Institute of Advanced Industrial Science and Technology, 脳神経情報研究部門, 主任研究員 2008: 独立行政法人産業技術総合研究所, 脳神経情報研究部門, 主任研究員 2007: 産業技術総合研究所, 脳神経情報研究部門, 主任研究員 2006: 独立行政法人産業技術総合研究所, 脳神経情報研究部門, 主任研究員 Less
Review Section/Research Field	Principal Investigator Neuroscience in general / Neuroscience in general Except Principal Investigator Basic Section 59010:Rehabilitation science-related / Biological Sciences / Neurophysiology and muscle physiology
Keywords	Principal Investigator 活動利敵 / メタ可塑性 / 受容体輸送 / 活動履歴 / 受容体 / シナプス可塑性 / 膜輸送 / 2光子吸収 / 脳・神経 / 可視化 / 光スイッチ / 脳・神経科学 / 神経科学 … More Except Principal Investigator … More シナプス / 行動解析 / 習慣的運動 / オリゴマー / トランスジェニックマウス / アミロイドβタンパク質 / アルツハイマー病 / 神経科学 / 細胞・組織 / 蛋白質 / 脳神経 / ドーパミン受容体 / GFP / 認知機能 / 運動 / 歩行 / 脊髄 / 生理学 / 神経回路 / ニューロン / 神経 / 遺伝子 / 脳・神経 / 遣伝子 Less

アルツハイマー病による認知機能障害に対する習慣的運動とドーパミン受容体の役割
- Principal Investigator
  
  落石知世
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Analysis of the mechanism of effects of habitual exercise on cognitive dysfunction induced by amyloid beta oligomers
- Principal Investigator
  
  OCHIISHI TOMOYO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
The role of Rab effector protein in the AMPA receptor trafficking associated with neural activity historyPrincipal Investigator
- Principal Investigator
  
  KIYOSUE Kazuyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  National Institute of Advanced Industrial Science and Technology
前駆体BDNFによる神経回路の形成と機能に対する負の制御とその生理的役割
- Principal Investigator
  
  小島正己
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Analysis of synaptic molecules trafficking by using 2-photon activation of photo-activatable moleculePrincipal Investigator
- Principal Investigator
  
  KIYOSUE Kazuyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Electrophysiological characterization of locomotor-related inhibitory neurons in the spinal cord
- Principal Investigator
  
  NISHIMARU Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  University of Tsukuba
PrecursorBDNFによるシナプス退縮のメカニズムとその生理的役割
- Principal Investigator
  
  小島正己
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute of Advanced Industrial Science and Technology

All 2022 2019 2013 2012 2010 2009 2007 Other

All Journal Article Presentation

[Journal Article] New Alzheimer’s disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid β oligomers2019
- Author(s)
  Ochiishi Tomoyo、Kaku Masami、Kiyosue Kazuyuki、Doi Motomichi、Urabe Takao、Hattori Nobutaka、Shimura Hideki、Ebihara Tatsuhiko
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 17368-17368
- DOI
  10.1038/s41598-019-53415-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K11362, KAKENHI-PROJECT-16K16434
[Journal Article] 受容体の膜輸送によるシナプス機能制御2010
- Author(s)
  清末和之
- Journal Title
  
  生体の科学特集シナプスをめぐるシグナリング
  
  Volume: Vol61,No5 Pages: 534-536
- Data Source
  KAKENHI-PROJECT-20500304
[Journal Article] 受容体の膜輸送によるシナプス機能制御2010
- Author(s)
  清末和之
- Journal Title
  
  生体の科学特集シナプスをめぐるシグナリング Vol61, No5
  
  Pages: 534-536
- Data Source
  KAKENHI-PROJECT-20500304
[Journal Article] Multiple functions of precursor BDNF to CNS neurons : negative regulation of neurite growth, spine formation and cell survival2009
- Author(s)
  Koshimizu, H., Kiyosue, K., Hara, T., Hazama, S., Suzuki, S., Uegaki, K., Nagappan, G., Zaitsev, E., Hirokawa, T., Tatsu, Y., Ogura, A., Lu, B., Kojima M
- Journal Title
  
  Mol.Brain 2
  
  Pages: 1-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20021035
[Journal Article] Brain-derived neurotrophic factor(BDNF)stimulates cholesterol biosynthesis and accumulates presynaptic proteins in lipid rafts A novel role for BDNF in synapse development2007
- Author(s)
  Suzuki S., Kiyosue. K, Hazama, S, Ogura A, Kashihara M, Hara T, Koshizu H, Kojima M
- Journal Title
  
  J Neurosci 27
  
  Pages: 6417-6427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18021042
[Presentation] A new mouse model of Alzheimer's disease to analyze the toxicity of amyloid β oligomers2022
- Author(s)
  Tomoyo Ochiishi, Masami Kaku, Kazuyuki Kiyosue, Motomichi Doi, Hideki Shimura, Tatsuhiko Ebihara
- Organizer
  20th Biennial Conference of Association of Gerontology (India)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11305
[Presentation] Cognitive impairment caused by intracellular amyloid β oligomers is ameliorated by voluntary exercise with a running wheel2022
- Author(s)
  Tomoyo Ochiishi, Masami Kaku, Kazuyuki Kiyosue
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-22K11305
[Presentation] Characteristic feature of new Alzheimer’s disease model mouse that expressing amyloid β oligomer intraneuronally2019
- Author(s)
  Tomoyo Ochiishi, Masami Kaku, Kazuyuki Kiyosue, Motomichi Doi, Tatsuhiko Ebihara.
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K11362
[Presentation] 神経活動依存的Rabaptin-5の制御がLTP発現時のAMPA受容体の表面発現を調整する2013
- Author(s)
  清末和之、亀山仁彦
- Organizer
  日本神経科学学会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-24500400
[Presentation] Inactivity up-regulates the levels of rabaptin-5 leading to enhancement of synaptic delivery of GluA12012
- Author(s)
  kazuyuki KIYOSUE and Kimihiko Kameyama
- Organizer
  American society of cell biology
- Place of Presentation
  San Francisco
- Data Source
  KAKENHI-PROJECT-24500400
[Presentation] 神経活動依存的Rabaptin-5の制御がグルタミン酸受容体サブユニット依存したシナプス輸送を制御する。2012
- Author(s)
  清末和之、亀山仁彦
- Organizer
  日本神経科学学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24500400
[Presentation] Synaptic activity controls the levels of rabaptin-5 leading to the alteration of glutamate receptor delivery to the synapse2012
- Author(s)
  kazuyuki KIYOSUE and Kimihiko KAMEYAMA
- Organizer
  Society for Neuroscience
- Place of Presentation
  New Orleans
- Data Source
  KAKENHI-PROJECT-24500400
[Presentation] Tracking of synaptic proteins at synapse by photoactivatable GFP in hippocampal neurons2009
- Author(s)
  清末和之
- Organizer
  日本生物物理学会
- Place of Presentation
  アスティ徳島(徳島県)
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-20500304
[Presentation] 膜輸送関連Rabエフェクター蛋白質のスプライスバリアントによるAMPA受容体輸送
- Author(s)
  清末和之、亀山仁彦
- Organizer
  日本神経科学学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-11 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24500400
[Presentation] Epstein Barrウイルス由来の発現ベクターは神経細胞での長期安定発現に有効である。
- Author(s)
  大西恵　清末和之
- Organizer
  日本神経科学学会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-07-28 – 2015-07-31
- Data Source
  KAKENHI-PROJECT-24500400

1. OCHIISHI TOMOYO (30356729)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. 小島正己 (40344171)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. KAMEYAMA Kimihiko (50224697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NISHIMARU Hiroshi (20302408)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 武井延之 (70221372)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kiyosue Kazuyuki 清末 和之

清末 和之 キヨスエ カズユキ

KIYOSUE Kazuyuki 清末 和之

Research Projects

Research Products

Co-Researchers

アルツハイマー病による認知機能障害に対する習慣的運動とドーパミン受容体の役割

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the mechanism of effects of habitual exercise on cognitive dysfunction induced by amyloid beta oligomers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of Rab effector protein in the AMPA receptor trafficking associated with neural activity historyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

前駆体BDNFによる神経回路の形成と機能に対する負の制御とその生理的役割

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of synaptic molecules trafficking by using 2-photon activation of photo-activatable moleculePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Electrophysiological characterization of locomotor-related inhibitory neurons in the spinal cord

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PrecursorBDNFによるシナプス退縮のメカニズムとその生理的役割

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] New Alzheimer’s disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid β oligomers2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 受容体の膜輸送によるシナプス機能制御2010

Author(s)

Journal Title

Data Source

[Journal Article] 受容体の膜輸送によるシナプス機能制御2010

Author(s)

Journal Title

Data Source

[Journal Article] Multiple functions of precursor BDNF to CNS neurons : negative regulation of neurite growth, spine formation and cell survival2009

Author(s)

Journal Title

Data Source

[Journal Article] Brain-derived neurotrophic factor(BDNF)stimulates cholesterol biosynthesis and accumulates presynaptic proteins in lipid rafts A novel role for BDNF in synapse development2007

Author(s)

Journal Title

Data Source

[Presentation] A new mouse model of Alzheimer's disease to analyze the toxicity of amyloid β oligomers2022

Author(s)

Organizer

Data Source

[Presentation] Cognitive impairment caused by intracellular amyloid β oligomers is ameliorated by voluntary exercise with a running wheel2022

Author(s)

Organizer

Data Source

[Presentation] Characteristic feature of new Alzheimer’s disease model mouse that expressing amyloid β oligomer intraneuronally2019

Author(s)

Organizer

Kiyosue Kazuyuki 清末和之

清末和之キヨスエカズユキ

KIYOSUE Kazuyuki 清末和之