• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Yatsuhashi Hiroshi  八橋 弘

… Alternative Names

YATSUHASHI Hiroshi  八橋 弘

Less
Researcher Number 50360855
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-5487-3403
External Links
Affiliation (Current) 2025: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 肝臓内科, 名誉院長
Affiliation (based on the past Project Information) *help 2006: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 治療研究部, 部長
2006: Nagasaki Medical Center, Clinical Research Center, Director of the Department of Therapeutic Research, 臨床研究センター・治療研究部, 部長
2005: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 治療研究部, 治療研究部長
2005: National Hospital Organization, Nagasaki Medical Center, Clinical Research Center, Department of Therapeutic Research, Director, 臨床研究センター, 治療研究部長
2004: National Hospital Organization Nagasaki Medical Center, Clinical Research Center, Department of Therapeutic Research, Director, 長崎医療センター・臨床研究センター, 治療研究部長 … More
2004: National Hospital Organization Nagasaki Medical Center, Clinical Research Center, Department of Therapeutic Research, 長崎医療センター・臨床研究センター, 治療研究部長
2004: 独立行政法人国立病院機構長崎医療センター, 臨床研究センター, 治療研究部長
2003: 国立病院, 長崎医療センター・臨床研究センター, 治療研究部長
2003: 国立病院長崎医療センター(臨床研究センター), 治療研究部長
2003: 国立病院長崎医療センター, 臨床研究センター, 治療研究部長 Less
Review Section/Research Field
Principal Investigator
Gastroenterology
Except Principal Investigator
Gastroenterology / General surgery / 膠原病・アレルギー・感染症内科学
Keywords
Principal Investigator
IFN Receptor / IFN Management / IFN Signal / Chronic Hepatitis C / IFNレセプター / IFN治療 / IFNシグナル / C型慢性肝炎
Except Principal Investigator
NHOSLJ / primary biliary cirrhosis … More / laser microdissection / 抗gp210抗体 / 原発性胆汁性肝硬変 / anti-nuclear antibodies / anti-mitochondrial antibodies / predictive autoantibodies / anti-centromere antibodies / anti-gp210 antibodies / 自然免疫 / 胆管上皮細胞 / TLR3 / centromere / gp210 / 分子標的 / 抗核抗体 / 抗ミトコンドリア抗体 / 予後予測抗体 / 抗セントロメア抗体 / Gene transfer / Hepatocyte transplantation / Bioartificial liver / Bank of hepatocytes / Human hepatocyte / 肝不全 / ヒト肝細胞化マウス / 凍結保存 / 人畜共通感染症 / キメラマウス / 遺伝子導入 / 肝細胞移植 / 人工肝臓 / 肝細胞バンク / ヒト肝細胞 / gene expression / anti-gp210 antibody / prognostic marker / etiology-associated antigen / chronic hepatitis C / autoimmune hepatitis / 遺伝子発現 / 予後予測因子 / 病因関連抗原 / 慢性C型肝炎 / 自己免疫性肝炎 / 肝細胞癌 / 哺乳類細胞発現ベクター / DNA修復機構関連蛋白 / 肝発癌機構 / 遺伝子クローニング / DNA修復酵素 / HCVコア蛋白 / C型肝炎ウイルス Less
  • Research Projects

    (5 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (6 People)
  •  Identification of new molecular targets and the study for the mechanism of bile ducts-and hepatocyte-destruction in primary biliary cirrhosis

    • Principal Investigator
      NAKAMURA Minoru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      National Hospital Organization(NHO) Nagasaki Medical Center
  •  C型肝炎ウイルスコア蛋白と結合するDNA修復酵素の遺伝子クローニング

    • Principal Investigator
      ISHIBASHI Hiromi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Single nucleotide polymorphisms in interferon signaling pathway and immuno system response to interferon treatment in hepatitis C patientsPrincipal Investigator

    • Principal Investigator
      YATSUHASHI Hiroshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      National Hospital Organization Nagasaki Medical Center, Clinical Research Center
  •  Construction of antibody-library to identify etiology-associated-antigen

    • Principal Investigator
      NAKAMURA Minoru
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      膠原病・アレルギー・感染症内科学
    • Research Institution
      National Hospital Organization Nagasaki Medical Center, Clinical Research Center
  •  Clinical application of bioartifical liver support and heopatocyte transplantation using human hepatocytes

    • Principal Investigator
      FUJIOKA Hikaru
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      National Hospital Organization Nagasaki Medical Center Clinical Research Center

All 2006 2005 2004 2003 2002

All Journal Article Book

  • [Book] IFN Receptor and IFN Signals : In Therapy for Viral Hepatitis and Prevent ion of Hepatocellular Carcinoma(M.Omata, K.Okita (Eds.))2004

    • Author(s)
      H.Yatsuhashi
    • Publisher
      Springer-Verlag
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Book] IFN Receptor and IFN Signals : In Therapy for Viral Hepatitis and Prevention of Hepatocellular Carcinoma(M.Omata, K.Okita(Eds.))2004

    • Author(s)
      H.Yatsuhashi
    • Publisher
      Springer-Verlag
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] Immunosuppressive FK506 inhibits matrix metalloproteinase-9 induction in TNF-alpha-stimulated human hepatic stellate cells.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Yokoyama T, Takii Y, Mod T, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      Life Sci. 78(21)

      Pages: 2510-2515

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Serum cytokine and soluble cytokine receptor levels in patients with non-alcoholic steatohepatitis.2006

    • Author(s)
      Abiru S, Migita K, Maeda Y, Daikoku M, Ito M, Ohata K, Nakamura M, Komori A, Yano K, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      Liver Int. 26(1)

      Pages: 39-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Serum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infection.2006

    • Author(s)
      Migita K, Abiru S, Maeda Y, Daikoku M, Ohata K, Nakamura M, Komori A, Yano K, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      Human Immunol. 67(1-2)

      Pages: 27-32

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y, Koyabu M, Matsuyama M, Mori T, Kamihira T, Daikoku M, Migita K, Yatsuhashi H, Nozaki N, Shimoda S, Ishibashi H
    • Journal Title

      J.Autoimmunity 26(2)

      Pages: 138-145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] IgA class antibodies to 2-oxo-acid dehydrogenase complex are not predictive markers of histopathological progression in primary biliary cirrhosis.2006

    • Author(s)
      Omagari K, Kadokawa Y, Nakamura M, Akazawa S, Ohba K, Ohnita K, Mizuta Y, Daikoku M, Yatsuhashi H, Ishibashi H, Kohno S.
    • Journal Title

      Autoimmunity 39(2)

      Pages: 107-112

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Polymorhisms of interleukin-1beta in Japanese patients with hepatitis B virus infection.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Miyazoe S, Nakao K, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      J Hepatol. (Epub ahead of print)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Relationship between serum resistin concentrations and inflammatory markers in patients with type 2 diabetes mellitus.2006

    • Author(s)
      Hui-Bing H, Migita K, Miyashita T, Maeda Y, Nakamura M, Yatsuhashi H, Ishibashi H, Eguchi K, Kimura H.
    • Journal Title

      Metabolism. 55

      Pages: 1670-1673

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] HLA-DRB1^*04 alleles in Japanese rheumatoid arthritis patients with AA amyloidosis.2006

    • Author(s)
      Migita K, Nakamura T, Maeda Y, Miyashita T, Origuchi T, Yatsuhashi Y, Nakamura M, Ishibashi H, Eguchi K.
    • Journal Title

      J Rheumatol. 33

      Pages: 2120-2123

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y, Koyabu M, Matsuyama M, Mori T, Kamihira T, Daikoku M, Migita K, Yatsuhashi H, Nozaki N, Shimoda S, Ishibashi H.
    • Journal Title

      J.Autoimmunity 26(2)

      Pages: 138-145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Immunosuppressant FK506 inhibits matrix metalloproteinase-9 induction in TNF-alpha-stimulated human hepatic stellate cells.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Yokoyama T, Takii Y, Mori T, Yatsuhashi H, Eguchi K, Ishibashi H
    • Journal Title

      Life Sci. 78(21)

      Pages: 2510-2515

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M, Takii Y, Kamihira T, Shimoda S, Mori T, Fujiwara S, Koyabu M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Ishibashi H
    • Journal Title

      Liver Int. 26(4)

      Pages: 467-476

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M, Ito M, Yokoyama T, Komori A, Shimizu-Yoshida Y, Nakao R, Kusumoto K, Nagaoka S, Yano K, Abiru S, Ueki T, Matsumoto T, Daikoku M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Nakashima M, Harada M, Ishibashi H
    • Journal Title

      Lab Invest. 85(7)

      Pages: 908-920

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis.2005

    • Author(s)
      Nakamura M, Shimizu-Yoshida Y, Takii Y, Komori A, Yokoyama T, Ueki T, Daikoku M, Yano K, Matsumoto T, Migita K, Yatsuhashi H, Ito M, Masaki N, Adachi H, Watanabe Y, Nakamura Y, Saoshiro T, Sodeyama T, Koga M, Shimoda S, Ishibashi H
    • Journal Title

      J.Hepatol. 42(3)

      Pages: 386-392

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591371
  • [Journal Article] Natural interferon α treatment and interferon α receptor 2 levels in a cute hepatitis C2004

    • Author(s)
      Ohata K, Yano K, Yatsuhashi H, Daikoku M, Koga M, Eguchi K, Yano M
    • Journal Title

      Dig Dis Sci 49・2

      Pages: 289-294

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] Natural interferon α treatment and interferon α receptor 2 levels in acute hepatitis C2004

    • Author(s)
      Ohata K, Yano K, Yatsuhashi H, Daikoku M, Koga M, Eguchi K, Yano M
    • Journal Title

      Dig Dis.Sci 49・2

      Pages: 289-294

    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] A low-density cDNA microarray with a unique reference RNA : pattern recognition analysis for IFN efficacy prediction to HCV as a model.2004

    • Author(s)
      Daiba A, Inaba N, Ando S, Kajiyama N, Yatsuhashi H, Terasaki H, Ito A, Ogasawara M, Abe A, Yoshioka J, Hayashida K, Kaneko S, Kohara M, Ito S.
    • Journal Title

      Biochem Biophys Res Commun 315(4)

      Pages: 1088-1096

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] B型肝炎可燃ウイルス(HBV) B型肝炎ウイルスのゲノム疫学2004

    • Author(s)
      八橋 弘
    • Journal Title

      日本臨牀 ウイルス性肝炎(下)-基礎・臨床研究の進歩 62・増刊号8

      Pages: 186-189

    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] B型肝炎ウイルス(HBV) B型肝炎ウイルスのゲノム疫学2004

    • Author(s)
      八橋 弘
    • Journal Title

      日本臨牀 ウイルス性肝炎(下) -基礎・臨床研究の進歩 62・増刊号8

      Pages: 186-189

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] IFN Receptor and IFN Signals2004

    • Author(s)
      H.Yatsuhashi
    • Journal Title

      Therapy for Viral Hepatitis and Prevention of Hepatocellular Carcinoma, (M.Omata, K.Okita (Eds.))(Springer-Verlag)

      Pages: 176-185

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] わが国のC型肝炎の現状,日本の肝癌は,なぜ多いのか2004

    • Author(s)
      八橋 弘
    • Journal Title

      日本消化器学会雑誌 101(6)

      Pages: 578-584

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] B型肝炎ウイルス(HBV),B型肝炎ウイルスのゲノム疫学2004

    • Author(s)
      八橋 弘
    • Journal Title

      日本臨牀ウイルス性肝炎(下)-基礎・臨床研究の進歩 62(増刊号8)

      Pages: 186-189

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] 特集/B型肝炎診療の進歩 IFN治療の滴応と問題点2004

    • Author(s)
      八橋 弘
    • Journal Title

      肝胆膵 49・4

      Pages: 471-477

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] 特集/B型肝炎診療の進歩,IFN治療の適応と問題点2004

    • Author(s)
      八橋 弘
    • Journal Title

      肝胆膵 49(4)

      Pages: 471-477

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] Natural interferon atreatment and interferon areceptor 2 levels in acute hepatitis C.2004

    • Author(s)
      Ohata K, Yano K, Yatsuhashi H, Daikoku M, Koga M, Eguchi K, Yano M.
    • Journal Title

      Dig Dis Sci 49(2)

      Pages: 289-294

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] 特集/B型肝炎診療の進歩 IFN治療の適応と問題点2004

    • Author(s)
      八橋 弘
    • Journal Title

      肝胆膵 49・4

      Pages: 471-477

    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] A low-density cDNA microarray with a unique reference RNA : pattern recognition analysis for IFN efficacy prediction to HCV as a model2004

    • Author(s)
      Daiba A, Inaba N, Ando S, Kajiyama N, Yatsuhashi H, Terasaki H, Ito A, Ogasawara M, Abe A, Yoshioka J, Hayashida K, Kaneko S, Kohara M, Ito S
    • Journal Title

      Biochem Biophys Res Commun 315・4

      Pages: 1088-1096

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] わが国のC型肝炎の現状 日本の肝癌は,なぜ多いのか2004

    • Author(s)
      八橋 弘
    • Journal Title

      日本消化器病学会雑誌 101・6

      Pages: 578-584

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] Interleukin-10 promoter polymorphisms and liver fibrosis progression in patients with chronic hepatitis C in Japan2003

    • Author(s)
      H.Hamada, H.Yatsuhashi, K.Yao, K.Arisawa, K.Nakao, M.Yano
    • Journal Title

      Journal of Hepatology 39・3

      Pages: 457-458

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] Interleukin-10 promoter polymorphisms and liver fibrosis progression in patients with chronic hepatitis C in Japan.2003

    • Author(s)
      H.Hamada, H.Yatsuhashi, K.Yano, K.Arisawa, K.Nakao, M.Yano
    • Journal Title

      Journal of Hepatology 39(3)

      Pages: 457-458

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] Influence of Interleukin-10 Gene Promoter Polymorphisms on Disease Progression in Patients Chronically Infected With Hepatitis B Virus.2002

    • Author(s)
      S.Miyazoe, K.Hamasaki, K.Nakata, Y.Kajiya, K.Kitajima, K.Nakao, M.Daikoku, H.Yatsuhashi, M.Koga, M.Yano, K.Eguchi
    • Journal Title

      Am J Gastroentero 197(8)

      Pages: 2086-2092

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • [Journal Article] Influence of Interleukin-10 Gene Promoter Polymorphisms on Disease Progression in Patients Chronically Infected With Hepatitis B Virus2002

    • Author(s)
      S.Miyazoe, K.Hamasaki, K.Nakata, Y.Kajiya, K.Kitajima, K.Nakao, M.Daikoku, H.Yatsuhashi, M.Koga, M.Yano, K.Eguchi
    • Journal Title

      Am J Gastroenterol 97・8

      Pages: 2086-2092

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15590710
  • 1.  ISHIBASHI Hiromi (80127969)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 13 results
  • 2.  NAKAMURA Minoru (40217906)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 13 results
  • 3.  FUJIOKA Hikaru (00264226)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 4.  YANO Koji (60360856)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 5.  KOMORI Atsumasa (50234901)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 6.  MIGITA Kiyoshi (60264214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results

URL: 

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi