FUJIWARA Naruyoshi 藤原成芳

Researcher Number	50365425
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2022: 聖マリアンナ医科大学, 医学部, 講師 2011 – 2016: 聖マリアンナ医科大学, 医学部, 助教 2009: Tokyo University of Science, 東京理科大学・薬学部, 助教 2008 – 2009: Tokyo University of Science, 薬学部, 助教 2007: The Research Institute, International Medical Center of Japan, Department of Intractable Diseases, Division of Clinical Immunnology, Fellow 2006: 国立国際医療センター(研究所), 流動研究員
Review Section/Research Field	Principal Investigator Medical pharmacy / Biomedical engineering/Biomaterial science and engineering / Regenerative medicine Except Principal Investigator Basic Section 90110:Biomedical engineering-related / Collagenous pathology/Allergology / Immunology / Regenerative medicine / Biological Sciences
Keywords	Principal Investigator ヒトiPS細胞 / 認知症 / 遺伝子製剤 / 医療薬剤学 / 神経科学 / 移植 / 脳神経疾患 / 再生医学 / 認知機能 / 神経移植 … More / 神経再生 / ブローカの対角帯垂直部 / 内側中隔核 / コリン作動性神経 / EphrinB / Disabled1 / シナプス / reelin / 神経幹細胞 / 神経分化 / 神経細胞移植 / 神経分化誘導 / 再生医療 / リポソーム / デコイ型遺伝子製剤 / IRF-1 / デコイ型遺伝子 / ナノドラッグ / ドラッグデリバリーシステム / マクロファージ / 結核 … More Except Principal Investigator NKG2D / 認知症 / 再生医療 / 転写制御 / NK細胞 / コリン神経 / 神経移植 / 認知機能 / ブローカの対角帯垂直部 / 内側中隔 / ヒト核蛋白陽性神経細胞 / コリン作動性神経 / 神経細胞移植 / 神経再生 / 全身性エリテマトーデス / 再発性多発軟骨炎 / 炎症性腸疾患 / Th17細胞 / 腸内細菌メタゲノミクス / Tリンパ球 / ベーチェット病 / T細胞 / 腸内細菌叢メタゲノミクス / Diabetes / autoimmunity / RAE-1 / NODマウス / 糖尿病 / 自己免疫疾患 / ヒトiPS細胞 / 記憶 / iPS / 遺伝子発現 / 移植 / 発がん / NKG2D リガンド / 免疫監視 Less

The effect of neural cell transplantation on the regeneration of cholinergic neurons
- Principal Investigator
  
  Okada Yoko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  St. Marianna University School of Medicine
Transplantation of Human iPS cell derived neurons to Dementia model micePrincipal Investigator
- Principal Investigator
  
  Fujiwara Naruyoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  St. Marianna University School of Medicine
Molecular mechanisms of the restoration of human APP transgenic mouse cognitive dysfunction after transplant of human iPS cell-derived neural cells
- Principal Investigator
  
  Arimitsu Nagisa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Regenerative medicine
- Research Institution
  St. Marianna University School of Medicine
eural stem/precursor derived from hiPS cells improved spatial memory learning of dementia model micePrincipal Investigator
- Principal Investigator
  
  Fujiwara Naruyoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Regenerative medicine
- Research Institution
  St. Marianna University School of Medicine
Establishment of an immune regulation of T cell function through gut microbiota modulation
- Principal Investigator
  
  Shimizu Jun
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  St. Marianna University School of Medicine
Development of shield-arms typed oligonucleotides for cancer therapyPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Naruyoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  St. Marianna University School of Medicine
The development of anti-tuberculosis gene drug inducing autophagy and activation of macrophagesPrincipal Investigator
- Principal Investigator
  
  FUJIWARA Naruyoshi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Tokyo University of Science
発がんによるNKG2Dリガンドの発現機構の解明(特定領域がん(発がん))
- Principal Investigator
  
  OGASAWARA Kouetsu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Research Institute, International Medical Center of Japan
Contribution of NK cells and NK related molecules in autoimmunity
- Principal Investigator
  
  OGASAWARA Kouetsu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Research Institute, International Medical Center of Japan

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2006 Other

All Journal Article Presentation Patent

[Journal Article] Roles of Reelin/Disabled1 pathway on functional recovery of hemiplegic mice after neural cell transplantation; Reelin promotes migration toward motor cortex and maturation to motoneurons of neural grafts.2019
- Author(s)
  Arimitsu N, Takai K, Fujiwara N, Shimizu J, Ueda Y, Wakisaka S, Hirotsu C, Murayama M A, Suzuki T, Suzuki N
- Journal Title
  
  Exp Neurol
  
  Volume: 320 Pages: 112970-112970
- DOI
  10.1016/j.expneurol.2019.112970
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09009, KAKENHI-PROJECT-19K20681, KAKENHI-PROJECT-17K01378, KAKENHI-PROJECT-17K10852, KAKENHI-PROJECT-17K11494, KAKENHI-PROJECT-17K14978
[Journal Article] Relative abundance of Megamonas hypermegale and Butyrivibrio species decreased in the intestine and its possible association with the T cell aberration by metabolite alteration in patients with Behcet's disease.2019
- Author(s)
  Shimizu J, Kubota T, Suzuki N et al.
- Journal Title
  
  Clinical Rheumatology
  
  Volume: 9 Issue: 5 Pages: 1-9
- DOI
  10.1007/s10067-018-04419-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09463, KAKENHI-PROJECT-18K09009, KAKENHI-PROJECT-17K01378, KAKENHI-PROJECT-17K10009, KAKENHI-PROJECT-17K11494
[Journal Article] Cellular and Molecular Mechanisms Governing Functional Recovery of Dementia Mice after Neuronal cell Transplantation.2018
- Author(s)
  Suzuki N, Shimizu J, Takai K, Arimitsu N, Suzuki T, Fujiwara N.
- Journal Title
  
  Journal of Neuroscience and Neurosurgery.
  
  Volume: 1(2) Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01378
[Journal Article] Propionate-producing bacteria in the intestine may associate with skewed responses of IL10-producing regulatory T cells in patients with relapsing polychondritis.2018
- Author(s)
  Shimizu J, Kubota T, Takada E, Takai K, Fujiwara N, Arimitsu N, Murayama MA, Ueda Y, Wakisaka S, Suzuki T, Suzuki N
- Journal Title
  
  PLoS One
  
  Volume: 20 Issue: 9 Pages: e0203657-e0203657
- DOI
  10.1371/journal.pone.0203657
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K01378, KAKENHI-PROJECT-17K10009, KAKENHI-PROJECT-17K10852, KAKENHI-PROJECT-17K14978
[Journal Article] Cellular and Molecular Mechanisms Governing Functional Recovery of Dementia Mice after Neuronal cell Transplantation.2018
- Author(s)
  Suzuki N, Shimizu J, Takai K, Arimitsu N, Suzuki T, Fujiwara N.
- Journal Title
  
  Journal of Neuroscience and Neurosurgery
  
  Volume: 1 Pages: 1-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K01378
[Journal Article] Neuronal cell sheets of cortical motor neuron phenotype derived from human iPS cells.2017
- Author(s)
  Suzuki N, Arimitsu N, Shimizu J, Takai K, Hirotsu C, Ueda Y, Wakisaka S, Fujiwara N, Suzuki T.
- Journal Title
  
  Cell Transplant.
  
  Volume: 26 Issue: 8 Pages: 1355-1364
- DOI
  10.1177/0963689717720280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10743, KAKENHI-PROJECT-16K10744, KAKENHI-PROJECT-16K11334, KAKENHI-PROJECT-17K01378, KAKENHI-PROJECT-17K10009, KAKENHI-PROJECT-17K10852, KAKENHI-PROJECT-17K11494, KAKENHI-PROJECT-26462172
[Journal Article] Human iPS cell derived neural cell sheets exhibit mature neural and extendable scaffold functions and promote recovery in injured mouse spinal cords.2016
- Author(s)
  Arimitsu N, Shimizu J, Iinuma M, Umehara T, Fujiwara N, Takai K, Wakisaka S, Hirotsu C, Suzuki T, Beppu M, Niki H, Suzuki N.
- Journal Title
  
  J Stem Cell Res Med.
  
  Volume: 1 Issue: 2 Pages: 41-47
- DOI
  10.15761/jscrm.1000106
- Open Access
- Data Source
  KAKENHI-PROJECT-26501005, KAKENHI-PROJECT-16K10743
[Journal Article] Bifidobacteria Abundance-Featured Gut Microbiota Compositional Change in Patients with Behcet’s Disease2016
- Author(s)
  1.Shimizu J, Kubota T, Takada E, Takai K, Fujiwara N, Arimitsu N, Ueda Y, Wakisaka S, Suzuki T, Suzuki N.
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 4 Pages: e0153746-e0153746
- DOI
  10.1371/journal.pone.0153746
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461488
[Journal Article] Sonic Hedgehog Supplementation Rapidly induces Myogenesis in Human Induced Pluripotent Stem Cells.2015
- Author(s)
  Shiratsuchi T, Misawa H, Fujiwara N, et al.
- Journal Title
  
  St. Marianna Medical J
  
  Volume: 6 Pages: 123-131
- NAID
  130005114674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25505006
[Journal Article] Generation of Retinal Progenitor Cell Sheets which Differentiate into Rhodopsin Positive Photoreceptors from Mouse iPS Cell Derived Retinal Progenitor Cell Clones2015
- Author(s)
  Noboru Suzuki, Jun Shimizu, Chieko Hirotsu, Erika Takada, Nagisa Arimitsu, Yuji Ueda, Naruyoshi Fujiwara, Tomoko Suzuki and Kenji Takai
- Journal Title
  
  International Journal of Ophthalmology and Clinical Research
  
  Volume: 2 Pages: 1-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25505006
[Journal Article] Generation of Retinal Progenitor Cell Sheets which Differentiate into Rhodopsin Positive Photoreceptors from Mouse iPS Cell Derived Retinal Progenitor Cell Clones.2015
- Author(s)
  1.Suzuki N, Shimizu J, Hirotsu C, Takada E, Arimitsu N, Ueda Y, Fujiwara N, SuzukiT, Takai K.
- Journal Title
  
  International Journal of Ophthalmology and Clinical Research
  
  Volume: 2 Pages: 1-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25505006
[Journal Article] Cellular and molecular mechanisms of the restoration of human APP transgenic mouse cognitive dysfunction after transplant of human iPS cell-derived neural cells.2015
- Author(s)
  4.Fujiwara N, Shimizu J, Takai K, Arimitsu N, Ueda Y, Wakisaka S, Suzuki T, Suzuki N.
- Journal Title
  
  Exp Neurol.
  
  Volume: 2 Pages: 423-431
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25505006
[Journal Article] Possible association of proinflammatory cytokines including IL1β and TNFα with enhanced Th17 cell differentiation in patients with Behcet's disease.2015
- Author(s)
  7.Shimizu J, Takai K, Takada E, Fujiwara N, Arimitsu N, Ueda Y, Wakisaka S, Suzuki T, Suzuki N.
- Journal Title
  
  Clin Rheumatol.
  
  Volume: 34 Issue: 7 Pages: 1-7
- DOI
  10.1007/s10067-015-2966-2
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461488
[Journal Article] Cellular and molecular mechanisms of the restoration of human APP transgenic mouse cognitive dysfunction after transplant of human iPS cell-derived neural cells.2015
- Author(s)
  ・Naruyoshi Fujiwara, Jun Shimizu, Kenji Takai, Nagisa Arimitsu, Yuji Ueda, Sueshige Wakisaka, Tomoko Suzuki, Noboru Suzuki.
- Journal Title
  
  Experimental Neurology
  
  Volume: 271 Pages: 423-431
- DOI
  10.1016/j.expneurol.2015.07.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25505007, KAKENHI-PROJECT-26501005, KAKENHI-PROJECT-25462237
[Journal Article] Induction of neural cells with spinal motoneuron phenotype from human iPS cells and the transplantation to totally transected spinal cords in mice.2015
- Author(s)
  3.Iinuma M, Umehara T, Arimitsu N, Shimizu J, Misawa H, Takai K, Fujiwara N, Fujii A, UedaY, Wakisaka S, Suzuki T, Hirotsu C, Beppu M, Suzuki N.
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 35 Pages: 154-163
- NAID
  130005078573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25505006
[Journal Article] Pax7 Gene Induction Rapidly Regulates Myocyte Homeostasis in Human Induced Pluripotent Stem (iPS) Cells.2014
- Author(s)
  Misawa H, Saito A, Shimizu J, Iinuma M, Shiratsuchi T, Fujiwara N, Takai K, Arimitsu N, Ueda Y, Wakisaka S, Suzuki T, Beppu M, Suzuki N.
- Journal Title
  
  St. Marianna Medical Journal.
  
  Volume: 5 Pages: 59-67
- NAID
  40020336414
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461488
[Journal Article] Pax7 Gene Induction Rapidly Regulates Myocyte Homeostasis in Human Induced Pluripotent Stem (iPS) Cells.2014
- Author(s)
  Hiroko Misawa, Asako Saito, Jun Shimizu, Masahiro IInuma, Takaki Shiratssuchi, Naruyoshi Fujiwara, Kenji Takai, Nagisa Arimitsu, Yuji Ueda, Dueshige Wakisaka, Tomoko Suzuki, Moroe Beppu, and Noboru Suzuki.
- Journal Title
  
  St. Marianna Medical Journal
  
  Volume: 5 Pages: 59-67
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25505006
[Journal Article] Human iPS Cell Derived Neurons with Cortical Motor Neuron Phenotype are Relevant for Functional Recovery of Hemiplegic Mice with Injured Motor Cortex.2013
- Author(s)
  T, Arimitsu N, Shimizu J, Takai K, Fujiwara N, Umehara T, Saito A, Ueda Y, Wakisaka S, Suzuki T, Hashimoto T, Tanaka Y, Suzuki N.
- Journal Title
  
  St. Marianna Medical J
  
  Volume: 4 Pages: 31-40
- NAID
  40019942503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461488
[Journal Article] Restoration of spatial memory dysfunction of human APP transgenic mice by transplantation of neuronal precursors derived from human iPS cells.2013
- Author(s)
  Fujiwara N, Shimizu J, Takai K, Arimitsu N, Saito A, Kono T, Umehara T, Ueda Y, Wakisaka S, Suzuki T, Suzuki N.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 13 Pages: 947-6
- DOI
  10.1016/j.neulet.2013.10.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461488, KAKENHI-PROJECT-25505006
[Journal Article] IGFII/Akt Signaling Regulates Myocyte Homeostasis in Human Induced Pluripotent Stem (iPS) Cells.2013
- Author(s)
  Asako Saito, Jun Shimizu, Naruyoshi Fujiwara, Kenji Takai, Nagisa Arimitsu, Tasuku Umehara, Takao Kono, Hiroko Misawa, Yuji Ueda, Sueshige Wakisaka, Tomoko Suzuki, Moroe Beppu, Noboru Suzuki.
- Journal Title
  
  St. Marianna Medical J
  
  Volume: 4 Pages: 41-48
- NAID
  40019942512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25505006
[Journal Article] Transplantation of Motor Neurons Derived from Human iPS Cells into Total Transection Model of Spinal Cord Injury in Mice.2013
- Author(s)
  Umehara T, Arimitsu N, Iinuma M, Shimizu J, Takai K, Fujiwara N, Saito A, Kono T, Ueda Y, Wakisaka S, Suzuki T, Beppu M, Suzuki N.
- Journal Title
  
  St. Marianna Medical J
  
  Volume: 4 Pages: 21-30
- NAID
  40019942497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461488
[Journal Article] Human iPS Cell Derived Neurons with Cortical Motor Neuron Phenotype are Relevant for Functional Recovery of Hemiplegic Mice with Injured Motor Cortex.2013
- Author(s)
  3. Takao Kono, Nagisa Arimitsu, Jun Shimizu, Kenji Takai, Naruyoshi Fujiwara, Tasuku Umehara, Asako Saito, Yuji Ueda, Sueshige Wakisaka, Tomoko Suzuki, Takuo Hashimoto, Yuichiro Tanaka, Noboru Suzuki.
- Journal Title
  
  St. Marianna Medical J
  
  Volume: 4 Pages: 31-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25505006
[Journal Article] Transplantation of Motor Neurons Derived from Human iPS Cells into Total Transection Model of Spinal Cord Injury in Mice.2013
- Author(s)
  4. Tasuku Umehara, Nagisa Arimitsu, Masahiro Iinuma, Jun Shimizu, Kenji Takai, Naruyoshi Fujiwara, Asako Saito, Takao Kono, Yuji Ueda, Sueshige Wakisaka, Tomoko Suzuki, Moroe Beppu, Noboru Suzuki.
- Journal Title
  
  St. Marianna Medical J
  
  Volume: 4 Pages: 21-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25505006
[Journal Article] IGFII/Akt Signaling Regulates Myocyte Homeostasis in Human Induced Pluripotent Stem (iPS) Cells.2013
- Author(s)
  Saito A, Shimizu J, Fujiwara N, Takai K, Arimitsu N, Umehara T, Kono T, Misawa H, Ueda Y, Wakisaka S, Suzuki T, Beppu M, Suzuki N.
- Journal Title
  
  St. Marianna Medical J
  
  Volume: 4 Pages: 41-48
- NAID
  40019942512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461488
[Journal Article] Colloids and Surface B2010
- Author(s)
  T. Onoshita, N. Fujiwara, et al.
- Journal Title
  
  Biointerfaces 76
  
  Pages: 151-157
- Data Source
  KAKENHI-PROJECT-20790145
[Journal Article] The behavior of PLGA microspheres containing rifampicin in alveolar macrophages2010
- Author(s)
  T.Onishita, N.Fujiwara, et. al.
- Journal Title
  
  Colloids and Surface B : Biointerfaces 76
  
  Pages: 151-157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790145
[Journal Article] 自己免疫性糖尿病におけるNK活性化レセプターNKG2D2006
- Author(s)
  小笠原康悦, 藤原成芳
- Journal Title
  
  感染炎症免疫 36・2
  
  Pages: 60-62
- Data Source
  KAKENHI-PROJECT-18590484
[Journal Article] A novel avian homologue of CD72, chB1r, down modulates BCR-mediated activation signals.2006
- Author(s)
  Fujiwara N, Hidano S, Mamada H, Ogasawara K, Kitamura D, Cooper MD, Hozumi N, Chen CL, Goitsuka R
- Journal Title
  
  Int Immunol 18(5)
  
  Pages: 775-83
- NAID
  10020619940
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590484
[Journal Article] A novel avian homologue of CD72, chBlr, down modulates BCR-mediated activation signals2006
- Author(s)
  Fujiwara N, Hidano S, Mamada H, Ogasawara K, Kitamura D, Cooper MD, Hozumi N, Chen CL, Goitsuka R.
- Journal Title
  
  Int Immunol 18(5)
  
  Pages: 775-783
- Data Source
  KAKENHI-PROJECT-18590484
[Journal Article] A novel avian homologue of CD72, chB1r, down modulates BCR-mediated activation signals2006
- Author(s)
  Fujiwara N, Hidano S, Mamada H, Ogasawara K, Kitamura D, Cooper MD, Hozumi N, Chen CL, Goitsuka R.
- Journal Title
  
  Int Immunol 18(5)
  
  Pages: 775-783
- NAID
  10020619940
- Data Source
  KAKENHI-PROJECT-18012054
[Journal Article] 自己免疫性糖尿病におけるNK活性化レセプターNKG2D2006
- Author(s)
  小笠原康悦, 藤原成芳
- Journal Title
  
  感染炎症免疫 36・2
  
  Pages: 60-62
- Data Source
  KAKENHI-PROJECT-18012054
[Patent] Method of delivering agent into target cell2011
- Inventor(s)
  HAGA, Makoto; (JP).FUJIWARA, Naruyoshi; (JP).NISHI, Akihiro; (JP).KUBO, Satoru; (JP).KUSHIBIKI, Takanori; (JP)
- Industrial Property Rights Holder
  HAGA, Makoto [JP/JP]; (JP) (For US Only).FUJIWARA, Naruyoshi [JP/JP]; (JP) (For US Only).NISHI, Akihiro [JP/JP]; (JP) (For US Only).KUBO, Satoru [JP/JP]; (JP) (For US Only).KUSHIBIKI, Takanori[JP/JP]; (JP) (For US Only)
- Filing Date
  2011
- Overseas
- Data Source
  KAKENHI-PROJECT-23790202
[Presentation] 認知症モデルマウスを用いたヒトiPS由来神経細胞移植による認知機能改善における心理症状の評価と関連2019
- Author(s)
  村山正承, 藤原成芳, 高井憲治, 清水潤, 鈴木登
- Organizer
  第66回日本実験動物学会総会
- Data Source
  KAKENHI-PROJECT-17K01378
[Presentation] ヒトiPS由来神経細胞移植による認知機能改善メカニズムについての検討2019
- Author(s)
  藤原成芳, 高井憲治, 清水潤，鈴木登.
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17K01378
[Presentation] 神経移植による認知機能回復における神経再生及び回復メカニズムの解明2019
- Author(s)
  藤原成芳, 村山正承, 岡田容子, 高井憲治, 廣津千恵子, 高田えりか, 有光なぎさ, 清水潤, 鈴木登
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-17K01378
[Presentation] ヒトiPS由来神経細胞移植による認知機能改善における改善メカニズムの解明2018
- Author(s)
  藤原成芳、岡田容子、高井憲治、廣津千恵子、有光なぎさ、高田えりか、清水潤、鈴木登
- Organizer
  日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-17K01378
[Presentation] A STUDY ON THE IMPORTANCE OF REGENERATION OF GABAERGIC NEURONS IN RESTORING COGNITIVE FUNCTION BY HIPS DERIVED NEURAL CELL TRANSPLANTATION TO DEMENTIA MODEL MICE.2018
- Author(s)
  Fujiwara Naruyoshi, Takai Kenji, Shimizu Jun and Suzuki Noboru
- Organizer
  International society for stem cell research 14th annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01378
[Presentation] 幹細胞由来神経細胞移植による脳損傷マウスにおける神経再生.2017
- Author(s)
  有光なぎさ, 廣津千恵子, 高井憲治, 藤原成芳, 岡田容子、清水潤, 鈴木登.
- Organizer
  第１６回日本再生医療学会総会
- Place of Presentation
  宮城県仙台市(仙台国際センター)
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-26501005
[Presentation] ヒトiPS由来神経細胞移植による認知機能改善と改善メカニズムについての検討2017
- Author(s)
  藤原成芳、岡田容子、高井憲治、廣津千恵子、有光なぎさ、高田えりか、清水潤、鈴木登.
- Organizer
  第１６回日本再生医療学会総会
- Place of Presentation
  宮城県仙台市(仙台国際センター)
- Year and Date
  2017-03-09
- Data Source
  KAKENHI-PROJECT-26501005
[Presentation] RESTORATION OF REELIN/APOER2 INTERACTION RESTORE COGNITIVE DYSFUNCTION OF DEMENTIA MODER MICE AFTER TRANSPLANTATIOB OF HUMAN IPS CELL-DERIVED NEURAL STEM/PRECURSOR CELLS.2017
- Author(s)
  Fujiwara Naruyoshi, Takai Kenji, Shimizu Jun and Suzuki Noboru.
- Organizer
  International society for stem cell research 13th annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01378
[Presentation] Restoration of human APP transgenic mouse cognitive dysfunction after transplant of human iPS cell-derived neural stem/precursor cells.2016
- Author(s)
  Naruyoshi Fujiwara, Kenji Takai, Erika Takada, Chieko Hirotsu, Nagisa Arimitsu, Jun Shimizu and Noboru Suzuki
- Organizer
  INTERNATIONAL SOCIETY FOR STEM CELL RESERCH 14th ANNUAL MEETING
- Place of Presentation
  SAN FRANCISCO CALIFORNIA (USA)
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25505006
[Presentation] 脳損傷マウスに対する幹細胞由来神経細胞移植による神経再生.2016
- Author(s)
  有光なぎさ, 廣津千恵子, 高井憲治, 藤原成芳, 清水潤, 鈴木登.
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  神奈川県横浜市(パシフィコ横浜)
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26501005
[Presentation] RESTORATION OF HUMAN APP TRANSGENIC MOUSE COGNITIVE DYSFUNCTION AFTER TRANSPLANT OF HUMAN IPS CELL-DERIVED NEURAL STEM/PRECURSOR CELLS.2016
- Author(s)
  Fujiwara Naruyoshi, Kenji Takai, Chieko Hirotsu, Erika Takada, Nagisa Arimitsu, Jun Shimizu and Noboru Suzuki.
- Organizer
  International society for stem cell research 12th annual meeting
- Place of Presentation
  CALIFORNIA USA
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26501005
[Presentation] Human iPS derived neural stem/precursor improved spatial memory learning of dementia model mice.2015
- Author(s)
  Naruyoshi Fujiwara, Chika Suzuki, Kenji Takai, Erika Takada, Chieko Hirotsu, Nagisa Arimitsu, Jun Shimizu and Noboru Suzuki
- Organizer
  INTERNATIONAL SOCIETY FOR STEM CELL RESERCH 13th ANNUAL MEETING
- Place of Presentation
  STOCKHOLM (SWEDEN)
- Year and Date
  2015-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25505006
[Presentation] DIFFERENTIATION OF CHOLINERGIC NEURONS FROM HIPS CELLS AND RESTORATION OF COGNITIVE FUNCTION BY THEIR TRANSPLANTATION IN MICE WITH DEMENTIA2013
- Author(s)
  Naruyoshi Fujiwara, Kenji Takai, Erika Takada, Chieko Hirotsu, Nagisa Arimitsu, Asako Saito, Jun Shimizu, Noboru Suzuki.
- Organizer
  INTERNATIONAL SOCIETY FOR STEM CELL RESERCH 11TH ANNUAL MEETING
- Place of Presentation
  BOSTON, MA USA
- Data Source
  KAKENHI-PROJECT-25505006
[Presentation] ヒトiPS細胞から誘導した神経細胞移植によるヒトAPPトランスジェニックマウスにおける空間記憶能の改善の検討2013
- Author(s)
  藤原成芳、高井憲司、高田えりか、廣津千恵子、斉藤亜沙子、有光なぎさ、梅原亮、神野崇、清水潤、鈴木登
- Organizer
  第34回　日本炎症・再生医学会
- Place of Presentation
  京都国際会館
- Data Source
  KAKENHI-PROJECT-25505006
[Presentation] ヒトiPS細胞から誘導した神経細胞移植による認知機能改善効果の検討2013
- Author(s)
  藤原成芳、高井憲司、高田えりか、廣津千恵子、斉藤亜沙子、有光なぎさ、神野崇生、清水潤、鈴木登
- Organizer
  第109回　日本精神神経学会学術総会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-25505006
[Presentation] Effect of shield-arms typed oligonucleotides on regulation of tumor-associated macrophage function.2012
- Author(s)
  Fujiwara N, et, al.
- Organizer
  日本薬学会
- Place of Presentation
  札幌（北海道大学）
- Data Source
  KAKENHI-PROJECT-23790202
[Presentation] 癌治療を目的としたシールドアームズ型遺伝子製剤の開発2012
- Author(s)
  藤原成芳
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23790202
[Presentation] The development of anti-tuberculosis gene drug inducing autophagy and activating of macrophage2009
- Author(s)
  藤原成芳
- Organizer
  日本薬物動態学会
- Place of Presentation
  京都・国立京都国際会館
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-20790145
[Presentation] The development of anti-tuberculosis gene drug inducing autophagy and activating of macriphage2009
- Author(s)
  Naruyoshi Fujiwara, et al.
- Organizer
  日本薬物動態学会第2 4回年会
- Place of Presentation
  (ポスター)
- Data Source
  KAKENHI-PROJECT-20790145
[Presentation] ヒトiPS細胞から誘導した神経細胞移植による認知機能の改善とそのメカニズムについての検討
- Author(s)
  藤原成芳、高井憲司、鈴木千佳、広津千恵子、高田えりか、有光なぎさ、白土崇輝、清水潤、鈴木登
- Organizer
  第111回日本精神神経学会
- Place of Presentation
  大阪国際会議場　（大阪）
- Year and Date
  2015-06-04 – 2015-06-06
- Data Source
  KAKENHI-PROJECT-25505006
[Presentation] ヒトiPS由来神経細胞移植による空間記憶能の改善と改善メカニズムについての検討
- Author(s)
  藤原成芳、高井憲司、鈴木千佳、広津千恵子、高田えりか、有光なぎさ、白土崇輝、清水潤、鈴木登
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜　（横浜）
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25505006
[Presentation] Human iPS derived neural stem/precursor improved spatial memory learning of dementia model mice.
- Author(s)
  Fujiwara, Naruyoshi, Takai, Kenji, Suzuki, Chika, Hirotsu, Chieko, Takada, Erika, Arimitsu, Nagisa, Shimizu, Jun, Suzuki, Noboru
- Organizer
  ERNATIONAL SOCIETY FOR STEM CELL RESERCH 13th ANNUAL MEETING
- Place of Presentation
  STOCKHOLM SWEDEN
- Year and Date
  2015-06-24 – 2015-06-27
- Data Source
  KAKENHI-PROJECT-25505006
[Presentation] Restoration of spatial memory dysfunction of human APP transgenic mice by transplantation of neuronal precursors derived from human iPS cells
- Author(s)
  Naruyoshi Fujiwara, Kenji Takai, Erika Takada, Chieko Hirotsu, Nagisa Arimitsu, Jun Shimizu, Noboru Suzuki.
- Organizer
  INTERNATIONAL SOCIETY FOR STEM CELL RESERCH 12th ANNUAL MEETING
- Place of Presentation
  VANCOUVER CANADA
- Year and Date
  2014-06-18 – 2014-06-21
- Data Source
  KAKENHI-PROJECT-25505006

1. OGASAWARA Kouetsu (30323603)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. Takai Kenji (60121167)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
3. Arimitsu Nagisa (40408688)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
4. Shimizu Jun (30509964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. Takada Erika (90398959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. Hirotsu Chieko (90647174)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Okada Yoko (20793219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 村山正承 (60737675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TANAKA Kazusa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 鈴木登

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
11. 鈴木知子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

FUJIWARA Naruyoshi 藤原 成芳

Research Projects

Research Products

Co-Researchers

The effect of neural cell transplantation on the regeneration of cholinergic neurons

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Transplantation of Human iPS cell derived neurons to Dementia model micePrincipal Investigator

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Molecular mechanisms of the restoration of human APP transgenic mouse cognitive dysfunction after transplant of human iPS cell-derived neural cells

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eural stem/precursor derived from hiPS cells improved spatial memory learning of dementia model micePrincipal Investigator

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Establishment of an immune regulation of T cell function through gut microbiota modulation

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Development of shield-arms typed oligonucleotides for cancer therapyPrincipal Investigator

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The development of anti-tuberculosis gene drug inducing autophagy and activation of macrophagesPrincipal Investigator

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発がんによるNKG2Dリガンドの発現機構の解明(特定領域がん(発がん))

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Review Section

Research Institution

Contribution of NK cells and NK related molecules in autoimmunity

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[Journal Article] Roles of Reelin/Disabled1 pathway on functional recovery of hemiplegic mice after neural cell transplantation; Reelin promotes migration toward motor cortex and maturation to motoneurons of neural grafts.2019

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[Journal Article] Relative abundance of Megamonas hypermegale and Butyrivibrio species decreased in the intestine and its possible association with the T cell aberration by metabolite alteration in patients with Behcet's disease.2019

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[Journal Article] Cellular and Molecular Mechanisms Governing Functional Recovery of Dementia Mice after Neuronal cell Transplantation.2018

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[Journal Article] Propionate-producing bacteria in the intestine may associate with skewed responses of IL10-producing regulatory T cells in patients with relapsing polychondritis.2018

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[Journal Article] Cellular and Molecular Mechanisms Governing Functional Recovery of Dementia Mice after Neuronal cell Transplantation.2018

Author(s)

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FUJIWARA Naruyoshi 藤原成芳