HIROYAMA Takashi 寛山隆

… Alternative Names

寛山隆ヒロヤマタカシ

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Researcher Number	50373361
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, バイオリソース研究センター, 専任研究員
Affiliation (based on the past Project Information) *help	2011 – 2012: 独立行政法人理化学研究所, 細胞材料開発室, 専任研究員 2009: The Institute of Physical and Chemical Research, 細胞材料開発室, 専任研究員 2008: The Institute of Physical and Chemical Research, 細胞材料開発室, 研究員 2004 – 2006: 独立行政法人理化学研究所, 細胞材料開発室, 研究員
Review Section/Research Field	Principal Investigator General physiology / General medical chemistry / Hematology Except Principal Investigator Hematology
Keywords	Principal Investigator iPS / ES / 臍帯血 / 赤血球 / ｉＰＳ / ＥＳ / 赤血球分化 / 赤血球前駆細胞株 / iPS分化 / 前駆細胞株 … More / 分化 / ips / ROCK / Rac / WAVE2 / MEDEP / 細胞株 / NaB / PMA / K562 / Musashi2 / 肥満細胞 / ES細胞 / HoxA9 / Musashi … More Except Principal Investigator Hematopoietic stem cell / Bone marrow transplantation / Hematopoiesis / Nuclear transfer / Embryonic stem cell / 造血幹細胞 / 骨髄移植 / 血液 / 核移植 / 胚性幹細胞 Less

Analysis into terminal erythroid differentiation and trial for establishing human erythroid progenitor cell lines.Principal Investigator
- Principal Investigator
  
  HIROYAMA Takashi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  The Institute of Physical and Chemical Research
Mass production of enucleated erythrocyte from erythroid progenitor cell lines.Principal Investigator
- Principal Investigator
  
  HIROYAMA Takashi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The Institute of Physical and Chemical Research
Application of nuclear transferred embryonic stem cells for reconstitution of hematopoiesis
- Principal Investigator
  
  NAKAMURA Yukio
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Cell Engineering Division, RIKEN BioResource Center (RIKEN BRC)
血液細胞分化におけるMUSASHI遺伝子群の機能解析Principal Investigator
- Principal Investigator
  
  寛山隆
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  The Institute of Physical and Chemical Research

All 2013 2012 2011 2010 2009 2008 2006 2005 Other

All Journal Article Presentation Book

[Book] 目的別で選べる細胞培養プロトコール2012
- Author(s)
  中村幸夫、西條薫、寛山隆、他
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23790263
[Book] es細胞からの赤血球誘導2008
- Author(s)
  寛山隆、中村幸夫
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20790240
[Book] 改訂・培養細胞実験ハンドブック : ES細胞からの赤血球誘導2008
- Author(s)
  寛山隆, 他
- Total Pages
  6
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-20790240
[Book] 化学と生物 : 万能細胞からの赤血球前駆細胞株の樹立2008
- Author(s)
  寛山隆, 他
- Total Pages
  2
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-20790240
[Book] 万能細胞からの赤血球前駆細胞株の樹立2008
- Author(s)
  寛山隆、中村幸夫
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-20790240
[Journal Article] Establishment of immortalized human erythroid progenitor cell lines able to produce enucleated red blood cells.2013
- Author(s)
  Kurita R, Suda N, Sudo K, Miharada K, Hiroyama T, Miyoshi H, Tani K, Nakamura Y.
- Journal Title
  
  PLoS One.
  
  Volume: 8(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790263
[Journal Article] Plasticity of Cells and Ex Vivo Production of Red Blood Cells2011
- Author(s)
  Hiroyama T, Miharada K, Kurita R, Nakamura Y
- Journal Title
  
  Stem Cells International
  
  Volume: 2011 Pages: 1-8
- DOI
  10.4061/2011/195780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790263
[Journal Article] Plasticity of Cells and Ex Vivo Production of Red Blood Cells.2011
- Author(s)
  Hiroyama T, Miharada K, Kurita R, Nakamura Y.
- Journal Title
  
  Stem Cells Int.
  
  Volume: 2011 Pages: 195780-195780
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790263
[Journal Article] Human Hematopoietic Stem Cells Can Survive In Vitro for Several Months.2009
- Author(s)
  Taro Ishigaki, Kazuhiro Sudo, Takashi Hiroyama, Kenichi Miharada, Haruhiko Ninomiya, Shigeru Chiba, Toshiro Nagasawa, Yukio Nakamura
- Journal Title
  
  Adv in Hematol 2009
- Data Source
  KAKENHI-PROJECT-20790240
[Journal Article] Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors.2008
- Author(s)
  Naoya Takayama, Hidekazu Nishikii, Joichi Usui, Hiroko Tsukui, Akira Sawaguchi, Takashi Hiroyama, Koji Eto, Hiromitsu Nakauchi
- Journal Title
  
  Blood 111
  
  Pages: 5298-5306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790240
[Journal Article] Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells.2008
- Author(s)
  Kenichi Miharada, Takashi Hiroyama, Kazuhiro Sudo, Inaho Danjo, Toshiro Nagasawa, Yukio Nakamura
- Journal Title
  
  J Cell Physiol. 215
  
  Pages: 526-537
- Data Source
  KAKENHI-PROJECT-20790240
[Journal Article] Long lasting in vitro hematopoiesis derived from primate embryonic stem cells.2006
- Author(s)
  Hiroyama, T., Miharada, K., Aoki, N., Fujioka, T., Sudo, K., Danjo, I., Nagasawa, T., Nakamura, Y.
- Journal Title
  
  Exp. Hematol. 34
  
  Pages: 760-769
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591020
[Journal Article] Mesenchymal progenitors able to differentiate into osteogenic, chondrogenic, and/or adipogenic cells in vitro are present in most primary fibroblast-like cell populations.2006
- Author(s)
  Sudo, K., Kanno, M., Miharada, K., Ogawa, S., Hiroyama, T., Saijo, K., Nakamura, Y.
- Journal Title
  
  Stem Cells (In press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591020
[Journal Article] Efficient enucleation of erythroblasts differentiated in vitro from hematopoietic stem and progenitor cells.2006
- Author(s)
  Miharada, K., Hiroyama, T., Sudo, K., Nagasawa, T., Nakamura, Y.
- Journal Title
  
  Nature Biotechnology 24
  
  Pages: 1255-1256
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591020
[Journal Article] Long lasting in vitro hematopoiesis derived from primate embryonic stem cells.2006
- Author(s)
  Hiroyama, T., Miharada, K., Aoki, N., Fujioka, T., Sudo, K., Danjo, I., Nagasawa, T., Nakamura, Y.
- Journal Title
  
  Experimental Hematology 34
  
  Pages: 760-769
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591020
[Journal Article] Long-lasting in vitro hematopoiesis derived from primate embryonic stem cells2006
- Author(s)
  Takashi Hiroyama, et al.
- Journal Title
  
  Experimental Hematology 34
  
  Pages: 760-769
- Data Source
  KAKENHI-PROJECT-16790550
[Journal Article] Refinement of cytokine use in the in vitro expansion of erythroid cells.2006
- Author(s)
  Miharada, K., Hiroyama, T., Sudo, K., Nagasawa, T., Nakamura, Y.
- Journal Title
  
  Human Cell 19
  
  Pages: 30-37
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591020
[Journal Article] Efficient enucleation of erythroblasts differentiated in vitro from hematopoietic stem and progenitor cells.2006
- Author(s)
  Miharada, K., Hiroyama, T., Sudo, K., Nagasawa, T., Nakamura, Y.
- Journal Title
  
  Nat. Biotechnol. 24
  
  Pages: 1255-1256
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17591020
[Journal Article] Lipocalin 2 functions as a negative regulator of red blood cell production in an autocrine fashion.2005
- Author(s)
  Miharada, K., Hiroyama, T., Sudo, K., Nagasawa, T., Nakamura, Y.
- Journal Title
  
  FASEB J. 19
  
  Pages: 1881-1883
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591020
[Journal Article] Refinement of cytokine use in the in vitro expansion of erythroid cells.
- Author(s)
  Miharada, K., Hiroyama, T., Sudo, K., Nagasawa, T., Nakamura, Y.
- Journal Title
  
  Human Cell (In press)
- Data Source
  KAKENHI-PROJECT-17591020
[Journal Article] Mesenchymal progenitors able to differentiate into osteogenic, chondrogenic, and/or adipogenic cells in vitro are present in most primary fibroblast-like cell populations.
- Author(s)
  Sudo, K., Kanno, M., Miharada, K., Ogawa, S., Hiroyama, T., Saijo, K., Nakamura, Y.
- Journal Title
  
  Stem Cells (doi : 10.1634/stemcells.2006-0504) (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591020
[Presentation] A USEFUL METHOD ABLE TO IDENTIFY THE GENES REQUIRED FOR TERMINAL ERYTHROID DIFFERENTIATION2012
- Author(s)
  Hiroyama T
- Organizer
  41st Annual Scientific Meeting of the ISEH
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-23790263
[Presentation] A useful method able to identify the genes required for terminal erythroid differentiation2012
- Author(s)
  Hiroyama T, Okada N, Kurita R, Nakamura Y.
- Organizer
  41st Annual Scientific Meeting of the ISEH.
- Place of Presentation
  Amsterdam
- Data Source
  KAKENHI-PROJECT-23790263
[Presentation] Enhanced Production of Hematopoietic Cells from Embryonic Stem Cells by Rho-kinase inhibitor2010
- Author(s)
  寛山隆
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20790240
[Presentation] Enhanced Production of Hematopoietic Cells from Embryonic Stem Cells by Rho-kinase inhibitor.2010
- Author(s)
  寛山隆、栗田良、岡田奈緒子、中村幸夫
- Organizer
  第9回日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20790240
[Presentation] 万能細胞による骨髄再構築、輸血医療は可能か?2009
- Author(s)
  寛山隆、中村幸夫
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2009-03-06
- Data Source
  KAKENHI-PROJECT-20790240
[Presentation] A Rho-kinase inhibitor Accelerates Production of Hematopoietic Cells from Embryonic Stem Cells.2009
- Author(s)
  Takashi Hiroyama, Ryo Kurita, Naoko Okada, Naoko Aoki, Yukio Nakamura
- Organizer
  ISEH 38th AnnualScientific Meeting
- Place of Presentation
  Athens
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-20790240
[Presentation] A Rho-kinase inhibitor Accelerates Production of Hematopoietic Cells from Embryonic Stem Cells2009
- Author(s)
  寛山隆
- Organizer
  ISEH 38th Annual Scientific Meeting
- Place of Presentation
  Athens
- Year and Date
  2009-09-10
- Data Source
  KAKENHI-PROJECT-20790240
[Presentation] Establishment of mouseembryonic stem cell-derived erythroid cell lines able to ameliorate acute anemia.2008
- Author(s)
  Takashi Hiroyama, Kenichi Miharada, Kazuhiro Sudo, Inaho Danjo, Naoko Aoki, Yukio Nakamura
- Organizer
  ISEH 37th Annual Scientific Meeting
- Place of Presentation
  Boston
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-20790240
[Presentation] Establishment of mouse embryonic stem cell-derived erythroid cell lines able to ameliorate acute anemia2008
- Author(s)
  Hiroyama, T., et al
- Organizer
  ISEH 37th Annual Scientific Meeting
- Place of Presentation
  Boston
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-20790240
[Presentation] マウス胚性幹細胞から樹立した赤血球系前駆細胞株(medeps)の性状の比較2008
- Author(s)
  寛山隆、三原田賢一、青木尚子、須藤和寛、檀上稲穂、中村幸夫
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-20790240
[Presentation] マウス胚性幹細胞から樹立した赤血球系前駆細胞株(MEDEPs)の性状の比較2008
- Author(s)
  寛山隆, 他
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  京都
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-20790240

1. NAKAMURA Yukio (60231479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. SUDO Kazuhiro (10392002)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results

HIROYAMA Takashi 寛山 隆

寛山 隆 ヒロヤマ タカシ

Research Projects

Research Products

Co-Researchers

Analysis into terminal erythroid differentiation and trial for establishing human erythroid progenitor cell lines.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mass production of enucleated erythrocyte from erythroid progenitor cell lines.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of nuclear transferred embryonic stem cells for reconstitution of hematopoiesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

血液細胞分化におけるMUSASHI遺伝子群の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 目的別で選べる細胞培養プロトコール2012

Author(s)

Publisher

Data Source

[Book] es細胞からの赤血球誘導2008

Author(s)

Publisher

Data Source

[Book] 改訂・培養細胞実験ハンドブック : ES細胞からの赤血球誘導2008

Author(s)

Total Pages

Publisher

Data Source

[Book] 化学と生物 : 万能細胞からの赤血球前駆細胞株の樹立2008

Author(s)

Total Pages

Publisher

Data Source

[Book] 万能細胞からの赤血球前駆細胞株の樹立2008

Author(s)

Publisher

Data Source

[Journal Article] Establishment of immortalized human erythroid progenitor cell lines able to produce enucleated red blood cells.2013

Author(s)

Journal Title

Data Source

[Journal Article] Plasticity of Cells and Ex Vivo Production of Red Blood Cells2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plasticity of Cells and Ex Vivo Production of Red Blood Cells.2011

Author(s)

Journal Title

Data Source

[Journal Article] Human Hematopoietic Stem Cells Can Survive In Vitro for Several Months.2009

Author(s)

Journal Title

Data Source

[Journal Article] Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors.2008

Author(s)

Journal Title

Data Source

[Journal Article] Lipocalin 2-mediated growth suppression is evident in human erythroid and monocyte/macrophage lineage cells.2008

Author(s)

Journal Title

Data Source

[Journal Article] Long lasting in vitro hematopoiesis derived from primate embryonic stem cells.2006

Author(s)

Journal Title

Description

HIROYAMA Takashi 寛山隆

寛山隆ヒロヤマタカシ