OGURA Keiji 小椋啓司

Researcher Number	50376456
Affiliation (based on the past Project Information) *help	2010: 東京大学, 医学部附属病院・消化器内科, 特任講師 2009: 東京大学, 医学部附属病院, 特任講師 2007: 東京大学, 医学部附属院, 助教 2005 – 2006: 東京大学, 医学部附属病院, 助手
Review Section/Research Field	Except Principal Investigator Gastroenterology
Keywords	Except Principal Investigator Ku70 / Runx3 / 癌 / Transcriptional Regulation / Suppression of Expression / Biotechnology / Protein / Cancer / Gene / 転写調節 … More / 発現抑制 / バイオテクノロジー / 蛋白質 / 遺伝子 / JNK / 動物モデル / 消化管 / 発がん / NF-κB / 炎症 / 癌・動物 Less

Mechanism of inflammation-associated gastro-intestinal carcinogenesis
- Principal Investigator
  
  MAEDA Shin
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Yokohama City University
  The Institute for Adult Diseases, Asahi Life Foundation
Genesis of gastric cancer caused by RUNX3 aberration
- Principal Investigator
  
  YAMAJI Yutaka
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo

All 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Apoptosis Signal-Regulating Kinase 1 regulates colitis and colitis-associated tumorigenesis via the innate immune responses.2010
- Author(s)
  Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Otsuka M, Ijichi H, Ikenoue T, Tateishi K, Akanuma M, Ogura K, Yoshida H, Ichijo H, Omata M, Maeda S.
- Journal Title
  
  Gastroenterology
  
  Volume: 138 Pages: 1055-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] IkappaB kinase beta regulates gastric carcinogenesis via IL-1α expression.2010
- Author(s)
  Sakamoto K, Hikiba Y, Nakagawa H, Hayakawa Y, Yanai A, Akanuma M, Ogura K, Yoshida H, Hirata Y, Kaestner KH, Omata M, Maeda S.
- Journal Title
  
  Gastroenterology 139
  
  Pages: 226-38
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Apoptosis Signal-Regulating Kinase 1 regulates colitis and colitis-associated tumorigenesis via the innate immune responses.2010
- Author(s)
  Hayakawa Y, Hirata Y, Nakagawa H, Sakamoto K, Hikiba Y, Otsuka M, Ijichi H, Ikenoue T, Tateishi K, Akanuma M, Ogura K, Yoshida H, Ichijo H, Omata M, Maeda S.
- Journal Title
  
  Gastroenterology 138
  
  Pages: 1055-1067
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth.2009
- Author(s)
  Sakamoto K, Maeda S, Hikiba Y, Nakagawa H, Hayakawa Y, Shibata W, Yanai A, Ogura K, Omata M.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 2248-2258
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009
- Author(s)
  Hayakawa Y, Maeda S, Nakagawa H, Hikiba Y, Shibata W, Sakamoto K, Yanai A, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
- Journal Title
  
  J Gastroenterol 44
  
  Pages: 935-943
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] IKKβ/NF-κB Activation Controls the Development of Liver Metastasis via IL-6 Expression.2009
- Author(s)
  Maeda S, Hikiba Y, Sakamoto K, Nakagawa H, Hirata Y, Hayakawa Y, Yanai A, Ogura K, Karin M, Omata M.
- Journal Title
  
  Hepatology 50
  
  Pages: 1851-1860
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] IKKβ/NF-κB Activation Controls the Development of Liver Metastasis via IL-6 Expression.2009
- Author(s)
  Maeda S, Hikiba Y, Sakamoto K, Nakagawa H, Hirata Y, Hayakawa Y, Yanai A, Ogura K, Karin M, Omata M.
- Journal Title
  
  Hepatology
  
  Volume: 50 Pages: 1851-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009
- Author(s)
  Hayakawa Y, Maeda S, Nakagawa H, Hikiba Y, Shibata W, Sakamoto K, Yanai A, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
- Journal Title
  
  J Gastroenterol
  
  Volume: 44 Pages: 935-943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth2009
- Author(s)
  Sakamoto K, Maeda S, Hikiba Y, Nakagawa H, Hayakawa Y, Shibata Y, Yanai A, Ogura K, Omata M.
- Journal Title
  
  Clinical Cancer Research 15
  
  Pages: 2248-58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice.2008
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Sakamoto K, Nakagawa H, Ogura K, Karin M, Omata M.
- Journal Title
  
  Cancer Res 68
  
  Pages: 5031-5039
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Activation of IkappaB kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils.2008
- Author(s)
  Yanai A, Maeda S, Shibata W, Hikiba Y, Sakamoto K, Nakagawa H, Ohmae T, Hirata Y, Ogura K, Muto S, Itai A, Omata M.
- Journal Title
  
  Infect Immun 76
  
  Pages: 781-787
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice2008
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Sakamoto K, Nakagawa H, Ogura K, Karin M, Omata M.
- Journal Title
  
  Cancer Research 68
  
  Pages: 5031-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Activation of Ikappa B kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils2008
- Author(s)
  Yanai A, Maeda S, Shibata W, Hikiba Y, Sakamoto K, Nakagawa H, ohmae T, Hirata Y, Ogura K, Muto S, Itai A, Omata M
- Journal Title
  
  Infect Immun 76
  
  Pages: 781-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Deletion of ASK1 attenuates acetaminophen-induced liver injury by inhibiting JNK activation2008
- Author(s)
  Nakagawa H, Maeda S, Hikiba Y, Ohmae T, Shibata W, Yanai A, Sakamoto K, Ogura K, Noguchi T, Karin M, Ichijo H, Omata M.
- Journal Title
  
  Gastroenterology 135
  
  Pages: 1311-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Cutting edge:The IkappaB kinase(IKK)inhibitor, NEMO-binding domain peptide, bloks inflammatory injury in murine colitis2007
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, Nakagawa H, Ogura K, Omata M
- Journal Title
  
  J Immunol 179
  
  Pages: 2681-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Cutting Edge : The I{kappa}B Kinase (IKK) Inhibitor, NEMO-Binding Domain Peptide, Blocks Inflammatory Injury in Murine Colitis.2007
- Author(s)
  Shibata W, Maeda S, Hikiba Y, Yanai A, Ohmae T, Sakamoto K, Nakagawa H, Ogura K, Omata M.
- Journal Title
  
  J Immunol 179
  
  Pages: 2681-2685
- Data Source
  KAKENHI-PROJECT-19390205
[Journal Article] Essential roles of high mobility group box 1 in the development of marine colitis and colitis-associated cancer2007
- Author(s)
  Maeda S, Hikiba Y, Shibata W, Ohmae T, Yanai A, Ogura K, Yamada S, Omata M
- Journal Title
  
  Siochem Biophys Res Commun 360
  
  Pages: 394-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] Colon cancer-derived factors activate NF-κB in myeloid cells via TLR2 to link inflammation and tumorigenesis2009
- Author(s)
  Shin Maeda, Yohko Hikiba, Kei Sakamoto, Hayato Nakagawa, Yoku Hayakawa, Yoshihiro Hirata, Keiji Ogura, Masao Omata
- Organizer
  Digestive Disease Week
- Place of Presentation
  Chicago
- Year and Date
  2009-05-05
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] Masao Omata Colon cancer-derived factors activate NF-κB in myeloid cells via TLR2 to link inflammation and tumorigenesis2009
- Author(s)
  Shin Maeda, Yohko Hikiba, Kei Sakamoto, Hayato Nakagawa, Yoku Hayakawa, Yoshihiro Hirata, Keiji Ogura
- Organizer
  Digestive Disease Week
- Place of Presentation
  Chicago
- Year and Date
  2009-05-05
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] c-Jun NH2-terminal kinase 1 is a criticalregulator for the development of chemical-induced gastric cancer in mice2008
- Author(s)
  Maeda S, Shibata W, Hikiba Y, Yanai A, Sakamoto 1 K, Nakagawa H, Ogura K, Karin M, Omata M.
- Organizer
  Digestive Disease Week
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-19390205
[Presentation] c-Jun NH2-terminal kinase 1 is a criticalregulator for the development of chemical-induced gastric cancer in mice.2008
- Author(s)
  Maeda S, Shibata W, Hikiba Y, Yanai A, Sakamotol K, Nakagawa H, Ogura K, Karin M, Omata M.
- Organizer
  Digestive Disease Week
- Data Source
  KAKENHI-PROJECT-19390205

1. MAEDA Shin (40415956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
2. SHIBATA Wataru (00435819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
3. YANAI Ayako (10415961)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
4. YAMAJI Yutaka (40376455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KANAI Fumihiko (70334399)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OGURA Keiji 小椋 啓司

Research Projects

Research Products

Co-Researchers

Mechanism of inflammation-associated gastro-intestinal carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genesis of gastric cancer caused by RUNX3 aberration

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Apoptosis Signal-Regulating Kinase 1 regulates colitis and colitis-associated tumorigenesis via the innate immune responses.2010

Author(s)

Journal Title

Data Source

[Journal Article] IkappaB kinase beta regulates gastric carcinogenesis via IL-1α expression.2010

Author(s)

Journal Title

Data Source

[Journal Article] Apoptosis Signal-Regulating Kinase 1 regulates colitis and colitis-associated tumorigenesis via the innate immune responses.2010

Author(s)

Journal Title

Data Source

[Journal Article] Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth.2009

Author(s)

Journal Title

Data Source

[Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009

Author(s)

Journal Title

Data Source

[Journal Article] IKKβ/NF-κB Activation Controls the Development of Liver Metastasis via IL-6 Expression.2009

Author(s)

Journal Title

Data Source

[Journal Article] IKKβ/NF-κB Activation Controls the Development of Liver Metastasis via IL-6 Expression.2009

Author(s)

Journal Title

Data Source

[Journal Article] Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.2009

Author(s)

Journal Title

Data Source

[Journal Article] Constitutive NF-κB activation in colorectal carcinoma plays a key role in angiogenesis, promoting tumor growth2009

Author(s)

Journal Title

Data Source

[Journal Article] c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice.2008

Author(s)

Journal Title

Data Source

[Journal Article] Activation of IkappaB kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils.2008

Author(s)

Journal Title

Data Source

[Journal Article] c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice2008

Author(s)

Journal Title

Data Source

[Journal Article] Activation of Ikappa B kinase and NF-kappaB is essential for Helicobacter pylori-induced chronic gastritis in Mongolian gerbils2008

Author(s)

Journal Title

Data Source

[Journal Article] Deletion of ASK1 attenuates acetaminophen-induced liver injury by inhibiting JNK activation2008

Author(s)

Journal Title

Data Source

[Journal Article] Cutting edge:The IkappaB kinase(IKK)inhibitor, NEMO-binding domain peptide, bloks inflammatory injury in murine colitis2007

Author(s)

Journal Title

Data Source

[Journal Article] Cutting Edge : The I{kappa}B Kinase (IKK) Inhibitor, NEMO-Binding Domain Peptide, Blocks Inflammatory Injury in Murine Colitis.2007

Author(s)

Journal Title

Data Source

OGURA Keiji 小椋啓司