KAMIJO YUJI 上條祐司

… Alternative Names

KAMIJO Yuji 上條祐司

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Researcher Number	50377636
Other IDs	https://orcid.org/0000-0001-8077-891X
Affiliation (Current)	2025: 信州大学, 学術研究院医学系(医学部附属病院), 准教授
Affiliation (based on the past Project Information) *help	2017 – 2025: 信州大学, 学術研究院医学系(医学部附属病院), 准教授 2014 – 2015: 信州大学, 学術研究院医学系(医学部附属病院), 准教授 2012 – 2013: 信州大学, 医学部附属病院, 講師 2011: 信州大学, 医学部附属病院, 助教 2010: 信州大学, 医学部・附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / General pharmacology Except Principal Investigator Basic Section 58060:Clinical nursing-related / General medical chemistry
Keywords	Principal Investigator 酸化ストレス / 脂肪酸代謝 / PPARα / 慢性腎臓病 / 不飽和脂肪酸 / 腎臓病 / 炎症 / 虚血再灌流 / 飢餓 / autophagy … More / 複合糖脂質 / 高脂血症 / ANCA関連腎炎 / オートファジー / 心臓血管病 / スルファチド / 血管炎症候群 / 脂質異常 / バイオマーカー / 糸球体活動性病変 / 尿毒素 / 脂質代謝 / 高血圧 / sulfatide / 蛋白尿 / 尿細管 / イルベサルタン / ＡＲＢ / ＰＰＡＲα / アンギオテンシンⅡレセプター拮抗薬 / ペルオキシソーム増殖剤活性化受容体 / 脂肪酸 / 腎保護 / アポトーシス / 尿細管障害 / 炎症反応 / 尿細管間質障害 / 糸球体腎炎 / 腎臓 … More Except Principal Investigator 看護教育プログラム / 意思決定支援 / 腎代替療法選択 / 慢性腎臓病 / Shared Decision Making / PPARα / 生体分子 / 酸化ストレス / スルファチド Less

腎のPPARα機能・脂肪酸代謝の低下が腎臓病と全身臓器に及ぼす影響の解析Principal Investigator
- Principal Investigator
  
  上條祐司
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Shinshu University
腎代替療法選択におけるSDM（共同意思決定）を実践するための看護教育プログラム開発
- Principal Investigator
  
  飯田美沙
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Nagoya City University
Analyses of the effects of autophagy-fatty acid metabolism crosstalk on kidney dysfunctionPrincipal Investigator
- Principal Investigator
  
  上條祐司
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Shinshu University
Clinical significance and mechanism of serum sulfatide abnormalities in chronic kidney diseasePrincipal Investigator
- Principal Investigator
  
  Kamijo Yuji
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Shinshu University
Studies on a novel oxidative stress-reducing effect resulting from generation/excretion of sulfated glycolipids
- Principal Investigator
  
  Nakajima Takero
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Shinshu University
Development of a new CKD therapy aimed for renoprotection by renal PPARalpha activationPrincipal Investigator
- Principal Investigator
  
  KAMIJO Yuji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Shinshu University
Development of the novel therapy against chronic kidney disease that utilizes PPAR α agonistPrincipal Investigator
- Principal Investigator
  
  KAMIJO Yuji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Shinshu University

All 2023 2022 2020 2019 2018 2017 2016 2015 2012 2011 Other

All Journal Article Presentation Book

[Book] 疾患モデルの作成と利用　脂質代謝異常と関連疾患（上巻）2015
- Author(s)
  中嶌岳郎、上條祐司、田中直樹、青山俊文　ほか
- Total Pages
  477
- Publisher
  株式会社　エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-25460329
[Journal Article] Serum Sulfatide Levels as a Biomarker of Active Glomerular Lesion in Patients with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: A Single Center Pilot Study2022
- Author(s)
  Harada Makoto、Nakajima Takero、Yamada Yosuke、Aomura Daiki、Yamaguchi Akinori、Sonoda Kosuke、Tanaka Naoki、Hashimoto Koji、Kamijo Yuji
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 3 Pages: 762-762
- DOI
  10.3390/jcm11030762
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17736, KAKENHI-PROJECT-18K08204, KAKENHI-PROJECT-21K11618
[Journal Article] Polyunsaturated fatty acid deficiency affects sulfatides and other sulfated glycans in lysosomes through autophagy-mediated degradation2020
- Author(s)
  Wang Y, Nakajima T, Diao P, Yamada Y, Nakamura K, Nakayama J, Tanaka N, Aoyama T, Kamijo Y
- Journal Title
  
  FASEB J .
  
  Volume: 34 Issue: 7 Pages: 9594-9614
- DOI
  10.1096/fj.202000030rr
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08204
[Journal Article] Effects of hypertension and antihypertensive treatments on sulfatide levels in serum and its metabolism2019
- Author(s)
  Guo Ran、Hu Xiao、Yamada Yosuke、Harada Makoto、Nakajima Takero、Kashihara Toshihide、Yamada Mitsuhiko、Aoyama Toshifumi、Kamijo Yuji
- Journal Title
  
  Hypertension Research
  
  Volume: 42 Issue: 5 Pages: 598-609
- DOI
  10.1038/s41440-018-0160-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06870, KAKENHI-PROJECT-18K08204, KAKENHI-PROJECT-19K17736
[Journal Article] Peroxisome proliferator-activated receptor α attenuates high-cholesterol diet-induced toxicity and pro-thrombotic effects in mice.2019
- Author(s)
  Lu Y, Harada M, Kamijo Y, Nakajima T, Tanaka N, Sugiyama E, Kyogashima M, Gonzalez FJ, Aoyama T.
- Journal Title
  
  Arch Toxicol.
  
  Volume: 93 Issue: 1 Pages: 149-161
- DOI
  10.1007/s00204-018-2335-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08204
[Journal Article] Impact of chronic kidney dysfunction on serum Sulfatides and its metabolic pathway in mice2018
- Author(s)
  Yamada Yosuke、Harada Makoto、Hashimoto Koji、Guo Ran、Nakajima Takero、Kashihara Toshihide、Yamada Mitsuhiko、Aoyama Toshifumi、Kamijo Yuji
- Journal Title
  
  Glycoconjugate Journal
  
  Volume: 36 Issue: 1 Pages: 1-11
- DOI
  10.1007/s10719-018-9850-7
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06870, KAKENHI-PROJECT-18K08204, KAKENHI-PROJECT-19K17736
[Journal Article] Decreased Fatty Acid <i>β</i>-Oxidation Is the Main Cause of Fatty Liver Induced by Polyunsaturated Fatty Acid Deficiency in Mice2017
- Author(s)
  Nakajima T, Yang Y, Lu Y, Kamijo Y, Yamada Y, Nakamura K, Koyama M, Yamaguchi S, Sugiyama E, Tanaka N, Aoyama T
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 242 Issue: 3 Pages: 229-239
- DOI
  10.1620/tjem.242.229
- NAID
  130005808367
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08264
[Journal Article] Age-dependent PPARα activation induces hepatic sulfatide accumulation in transgenic mice carrying the hepatitis C virus core gene.2016
- Author(s)
  Tian Y, Yang Y, Zhang X, Nakajima T, Tanaka N, Sugiyama E, Kamijo Y, Lu Y, Moriya K, Koike K, Gonzalez FJ, Aoyama T.
- Journal Title
  
  Glycoconj J
  
  Volume: 33 Issue: 6 Pages: 927-936
- DOI
  10.1007/s10719-016-9703-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08264, KAKENHI-PROJECT-16K08616
[Journal Article] Activation of PPARα by Fatty Acid Accumulation Enhances Fatty Acid Degradation and Sulfatide Synthesis.2016
- Author(s)
  Yang Y, Feng Y, Zhang X, Nakajima T, Tanaka N, Sugiyama E, Kamijo Y, Aoyama T.
- Journal Title
  
  Tohoku J Exp Med
  
  Volume: 240 Issue: 2 Pages: 113-22
- DOI
  10.1620/tjem.240.113
- NAID
  130005245903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08264
[Journal Article] Pharmacological and toxicological advances in PPAR-Related medicines2012
- Author(s)
  Kamijo Y et al
- Journal Title
  
  PPAR Res
  
  Volume: 1 Pages: 1-2
- DOI
  10.1155/2012/940964
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590238
[Journal Article] PPARα activation protects against anti-Thy1 nephritis by suppressing glomerular NF-κB signaling2012
- Author(s)
  Hashimoto K, Kamijo Y, Nakajima T, Harada M, Higuchi M, Ehara T, Shigematsu H, Aoyama T
- Journal Title
  
  PPAR Res
  
  Volume: 2012 Pages: 976089-976089
- DOI
  10.1155/2012/976089
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390060, KAKENHI-PROJECT-22590238
[Journal Article] Pretreatment by low-dose fibrates protects against acute free fatty acid-induced renal tubule toxicity by counteracting PPARα deterioration.2011
- Author(s)
  Takahashi K, Kamijo Y et al.
- Journal Title
  
  Toxicol Appl Pharmacol
  
  Volume: 252 Issue: 3 Pages: 237-49
- DOI
  10.1016/j.taap.2011.02.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590238
[Journal Article] Pretreatment by low-dose fibrates protects against acute free fatty acid-induced renal tubule toxicity by counteracting PPARa deterioration2011
- Author(s)
  高橋京子、上條祐司, 他
- Journal Title
  
  Toxicol Appl Pharmacol
  
  Volume: 252 Pages: 237-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590238
[Journal Article] PPARα activation protects against anti-Thy1 nephritis by suppressing glomerular NF-kB signaling
- Author(s)
  橋本幸始、上條祐司, 他
- Journal Title
  
  PPAR Research
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590238
[Presentation] 虚血性急性腎障害の重症化阻止に腎臓のPPARαは重要な役割を果たす2023
- Author(s)
  二村駿行、青村大輝、山家公輔、山田洋輔、原田真、橋本幸始、柳田素子、上條祐司
- Organizer
  第66回日本腎臓学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08306
[Presentation] PPARα in proximal tubule maintains serum glucose level against starvation2022
- Author(s)
  Aomura D, Nimura T, Yamada Y, Harada M, Hashimoto K, Yanagita M, Kamijo Y
- Organizer
  ASN Kidney Week 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08306
[Presentation] Serum sulfatide level as a marker for differentiation and activity assessment of sever renal vasculitis diseases.2022
- Author(s)
  Aomura D, Nimura T, Yamada Y, Harada M, Hashimoto K, Kamijo Y
- Organizer
  ASN 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08204
[Presentation] ANCA関連血管炎患者における血清Sulfatides値の意義の検討2022
- Author(s)
  原田真、中嶌岳郎、山田洋輔、山口晃典、園田光佑、山田愛子、岩渕良平、橋本幸始、上條祐司
- Organizer
  第65回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08204
[Presentation] PPARα in proximal tubules attenuates ischemic acute kidney injury2022
- Author(s)
  Nimura T, Aomura D, Yamada Y, Harada M, Hashimoto K, Yanagita M, Kamijo Y
- Organizer
  ASN Kidney Week 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08306
[Presentation] EFFECTS OF HYPERTENSION AND ANTIHYPERTENSIVE TREATMENTS ON SULFATIDE LEVELS IN SERUM AND ITS METABOLISM2019
- Author(s)
  Y. Kamijo, R. Guo, Y. Yamada, M. Harada, T. Nakajima, K. Hashimoto, T. Kashihara, Y. Mitsuhiko, T. Aoyama
- Organizer
  国際腎臓学会（WCN 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08204
[Presentation] 内因性抗凝固因子：スルファチド代謝に与える高血圧の影響について2019
- Author(s)
  上條祐司、山田洋輔、青村大輝、原田真、園田光佑、山口晃典、橋本幸始
- Organizer
  第62回日本腎臓学会
- Data Source
  KAKENHI-PROJECT-18K08204
[Presentation] IMPACT OF CHRONIC KIDNEY DYSFUNCTION ON SERUM SULFATIDES AND ITS METABOLIC PATHWAY IN MICE2019
- Author(s)
  Y. YAMADA, Y. Kamijo, A. Daiki.
- Organizer
  国際腎臓学会（WCN 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08204
[Presentation] DYSFUNCTION ON SERUM SULFATIDES AND ITS METABOLIC PATHWAY IN MICE.2019
- Author(s)
  Y. Yamada, Y. Kamijo, A. Daiki.
- Organizer
  国際腎臓学会（WCN 2019)（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08204
[Presentation] マウスにおける慢性腎機能障害が血清スルファチドとその代謝経路に与える影響.2019
- Author(s)
  山田洋輔、上條祐司.
- Organizer
  第62回日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08204
[Presentation] PPARαがコレステロール過剰摂取による血管内凝固作用を軽減する2018
- Author(s)
  上條祐司、山田洋輔、山口晃典、園田光佑、山田愛子、藤井一聡、原悠太、増田知恵、藤田識志、小川洋平、橋本幸始、中嶌岳郎、青山俊文
- Organizer
  第61回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-18K08204
[Presentation] Peroxisome proliferator-actitvated receptor α attenuates hypercholesterolemia-induced serum sulfatide abnormalities2018
- Author(s)
  Yuji Kamijo, Daiki Aomura, Shigekazu Kurihara, Takayuki Nimura, Makoto Harada
- Organizer
  アメリカ腎臓学会　（ASN Kidney Week 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08204
[Presentation] 5/6腎摘慢性腎臓病モデルマウスにおける血清スルファチド低下メカニズムの解明2018
- Author(s)
  山田洋輔、橋本幸始、上條祐司、中嶌岳郎、青山俊文
- Organizer
  第61回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-18K08204
[Presentation] イルベサルタンはマウス腎においてペルオキシソーム増殖剤活性化受容体alphaを介した腎保護作用を有する2016
- Author(s)
  原田真、橋本幸始、山田洋輔、中嶌岳郎、青山俊文、上條祐司
- Organizer
  第59回日本腎臓学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-06-19
- Data Source
  KAKENHI-PROJECT-25460329
[Presentation] PPARα活性化はNF-κB系を抑制し腎炎における糸球体障害を軽減する2012
- Author(s)
  橋本幸始、上條祐司　他
- Organizer
  第５５回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-22590238
[Presentation] PPARα活性化はNF-κB 系を抑制し腎炎における糸球体障害を軽減する2012
- Author(s)
  橋本幸始、上條祐司
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-03
- Data Source
  KAKENHI-PROJECT-22590238
[Presentation] PPAR αactivation improves glomerular injury caused by anti-Thy1 nephritis through suppression of NF- κ B signaling.2012
- Author(s)
  Hashimoto K, Kamijo Y et al
- Organizer
  ASN Kidney Week
- Place of Presentation
  San Diego, CA.
- Year and Date
  2012-11-02
- Data Source
  KAKENHI-PROJECT-22590238
[Presentation] PPARα Activation Improves Glomerular Injury Caused by Anti-Thy1 Nephritis through Suppression of NF-κB Signaling2012
- Author(s)
  Hashimoto K, Kamijo Y et al.
- Organizer
  ASN Kidney Week 2012
- Place of Presentation
  San Diego, CA
- Data Source
  KAKENHI-PROJECT-22590238
[Presentation] PPARα 活性化による2011
- Author(s)
  橋本幸始、上條祐司
- Organizer
  Thy1腎炎の組織障害軽減効果
- Place of Presentation
  横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-22590238
[Presentation] PPARα活性化によるThy1腎炎の組織障害軽減効果2011
- Author(s)
  橋本幸始、上條祐司, 他
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-22590238

1. AOYAMA Toshifumi (50231105)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
2. 田中直樹 (80419374)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. Nakajima Takero (30581011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. NAKAMURA Kozo (20345763)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 菅野祐幸 (40252663)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 飯田美沙 (70991181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 安東由佳子 (50314745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 金子さゆり (50463774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 原厚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 山田充彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 山田洋輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAMIJO YUJI 上條 祐司

KAMIJO Yuji 上條 祐司

Research Projects

Research Products

Co-Researchers

腎のPPARα機能・脂肪酸代謝の低下が腎臓病と全身臓器に及ぼす影響の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

腎代替療法選択におけるSDM（共同意思決定）を実践するための看護教育プログラム開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of the effects of autophagy-fatty acid metabolism crosstalk on kidney dysfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clinical significance and mechanism of serum sulfatide abnormalities in chronic kidney diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Studies on a novel oxidative stress-reducing effect resulting from generation/excretion of sulfated glycolipids

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new CKD therapy aimed for renoprotection by renal PPARalpha activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the novel therapy against chronic kidney disease that utilizes PPAR α agonistPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 疾患モデルの作成と利用 脂質代謝異常と関連疾患（上巻）2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Serum Sulfatide Levels as a Biomarker of Active Glomerular Lesion in Patients with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis: A Single Center Pilot Study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Polyunsaturated fatty acid deficiency affects sulfatides and other sulfated glycans in lysosomes through autophagy-mediated degradation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of hypertension and antihypertensive treatments on sulfatide levels in serum and its metabolism2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Peroxisome proliferator-activated receptor α attenuates high-cholesterol diet-induced toxicity and pro-thrombotic effects in mice.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of chronic kidney dysfunction on serum Sulfatides and its metabolic pathway in mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Decreased Fatty Acid <i>β</i>-Oxidation Is the Main Cause of Fatty Liver Induced by Polyunsaturated Fatty Acid Deficiency in Mice2017

Author(s)

Journal Title

KAMIJO YUJI 上條祐司

KAMIJO Yuji 上條祐司

[Book] 疾患モデルの作成と利用　脂質代謝異常と関連疾患（上巻）2015