Ariyasu Hiroyuki 有安宏之

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ARIYASU Hiroyuki 有安宏之

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Researcher Number	50378650
Affiliation (Current)	2025: 地方独立行政法人静岡県立病院機構静岡県立総合病院(救急診療部、循環器病診療部、がん診療部、臨床診療部, 臨床診療部, 部長
Affiliation (based on the past Project Information) *help	2013 – 2018: 和歌山県立医科大学, 医学部, 講師 2012: 京都大学, 医学研究科, 助教 2011 – 2012: 京都大学, 医学(系)研究科(研究院), 助教 2007 – 2010: Kyoto University, 医学研究科, 助教 2008: Kyoto University, 大学院医学研究科, 助教 2005 – 2006: 京都大学, 医学研究科, 助手
Review Section/Research Field	Principal Investigator Endocrinology Except Principal Investigator Endocrinology
Keywords	Principal Investigator グレリン / 成長ホルモン / 内分泌学 / 消化管ホルモン / 内分泌代謝学 / エネルギー代謝 / 摂食 / 遺伝子改変動物 / GH(成長ホルモン) / トランスジェニックマウス / ジフテリアトキシン受容体 … More Except Principal Investigator … More 糖尿病 / グレリン / 応用動物 / 遺伝子改変動物 / 消化管ホルモン / 糖代謝 / トランスジェニックマウス / Insulin / Pancreatic beta cell / Diabetes / Ghrelin / 膵臓β細胞 / インスリン / 肝臓β細胞 Less

Investigation of ghrelin effects on gut hormones and glucose metabolism using transgenic mice
- Principal Investigator
  
  AKAMIZU TAKASHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Wakayama Medical University
Physiological roles of free fatty acids in the regulation of food intakePrincipal Investigator
- Principal Investigator
  
  Ariyasu Hiroyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Wakayama Medical University
Physiological Roles of circulating ghrelin on food intake and energy homeostasisPrincipal Investigator
- Principal Investigator
  
  ARIYASU Hiroyuki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Kyoto University
The Analysis of Physiological Roles of circulating ghrelinPrincipal Investigator
- Principal Investigator
  
  ARIYASU Hiroyuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Kyoto University
Generation of a transgenic mouse that expressing human diphtheria toxin receptor cDNA under the control of the transcription regulatory regions of ghrelinPrincipal Investigator
- Principal Investigator
  
  ARIYASU Hiroyuki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  Kyoto University
Effect of ghrelin on pancreas beta cells and diabetic animal models
- Principal Investigator
  
  AKAMIZU Takashi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  Kyoto University

All 2018 2016 2015 2014 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] Differential role of GPR142 in tryptophan-mediated enhancement of insulin secretion in obese and lean mice2018
- Author(s)
  Ueda Yoko、Iwakura Hiroshi、Bando Mika、Doi Asako、Ariyasu Hiroyuki、Inaba Hidefumi、Morita Shuhei、Akamizu Takashi
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 6 Pages: 198762-198762
- DOI
  10.1371/journal.pone.0198762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09888, KAKENHI-PROJECT-16K09807
[Journal Article] Thyrotoxicosis and Adrenocortical Hormone Deficiency During Immune-checkpoint Inhibitor Treatment for Malignant Melanoma.2018
- Author(s)
  Ariyasu H, Inaba H, Ota T, Yamaoka H, Furukawa Y, Iwakura H, Doi N, Yamamoto Y, Akamizu T
- Journal Title
  
  In Vivo
  
  Volume: 32 Pages: 345-351
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09807
[Journal Article] Imbalanced Expression of IGF2 and PCSK4 Is Associated With Overproduction of Big IGF2 in SFT With NICTH: A Pilot Study2018
- Author(s)
  Kawai Shintaro、Ariyasu Hiroyuki、Uraki Shinsuke、Takeshima Ken、Morita Shuhei、Inaba Hidefumi、Iwakura Hiroshi、Doi Asako、Ohashi Takuya、Kawago Mitsumasa、Matsuoka Naoki、Okamura Shintaro、Tsujii Satoru、Akamizu Takashi
- Journal Title
  
  The Journal of Clinical Endocrinology & Metabolism
  
  Volume: 103 Issue: 7 Pages: 2728-2734
- DOI
  10.1210/jc.2018-00593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09888, KAKENHI-PROJECT-16K09807
[Journal Article] Reduced Expression of Mismatch Repair Genes MSH6/MSH2 Directly Promotes Pituitary Tumor Growth via the ATR-Chk1 Pathway2018
- Author(s)
  Uraki S, Ariyasu H, Doi A, Kawai S, Takeshima K, Morita S, Fukai J, Fujita K, Furuta H, Nishi M, Sugano K, Inoshita N, Nakao N, Yamada S, Akamizu T
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 103 Issue: 3 Pages: 1171-1179
- DOI
  10.1210/jc.2017-02332
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09807
[Journal Article] Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report2018
- Author(s)
  Takeshima Ken、Ariyasu Hiroyuki、Iwakura Hiroshi、Kawai Shintaro、Uraki Shinsuke、Inaba Hidefumi、Furuta Machi、Warigaya Kenji、Murata Shin-ichi、Akamizu Takashi
- Journal Title
  
  Diabetes Therapy
  
  Volume: 9 Issue: 3 Pages: 1385-1395
- DOI
  10.1007/s13300-018-0434-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09888, KAKENHI-PROJECT-16K09807
[Journal Article] Fulminant Type 1 Diabetes Mellitus Accompanied by Positive Conversion of Anti-insulin Antibody after the Administration of Anti-CTLA-4 Antibody Following the Discontinuation of Anti-PD-1 Antibody2018
- Author(s)
  Shiba Michiru、Inaba Hidefumi、Ariyasu Hiroyuki、Kawai Shintaro、Inagaki Yuko、Matsuno Shohei、Iwakura Hiroshi、Yamamoto Yuki、Nishi Masahiro、Akamizu Takashi
- Journal Title
  
  Intern. Med.
  
  Volume: 57 Issue: 14 Pages: 2029-2034
- DOI
  10.2169/internalmedicine.9518-17
- NAID
  130007404918
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2018-07-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09888, KAKENHI-PROJECT-16K09807
[Journal Article] High incorporation of long-chain fatty acids contributes to the efficient production of acylated ghrelin in ghrelin-producing cells.2016
- Author(s)
  Bando M, Iwakura H, Koyama H, Hosoda H, Shigematsu Y, Ariyasu H, Akamizu T, Kangawa K, Nakao K:
- Journal Title
  
  FEBS Lett
  
  Volume: 590 Pages: 992-1001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09807
[Journal Article] Comprehensive Profiling of GPCR Expression in Ghrelin-producing Cells.2016
- Author(s)
  Koyama H, Iwakura H, Dote K, Bando M, Hosoda H, Ariyasu H, Kusakabe T, Son C, Hosoda K, Akamizu T, Kangawa K, Nakao K.
- Journal Title
  
  Endocrinology
  
  Volume: 157 Issue: 2 Pages: 692-704
- DOI
  10.1210/en.2015-1784
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461331, KAKENHI-PROJECT-15K19532, KAKENHI-PROJECT-25461385
[Journal Article] High incorporation of long-chain fatty acids contributes to the efficient production of acylated ghrelin in ghrelin-producing cells.2016
- Author(s)
  Bando M, Iwakura H, Koyama H, Hosoda H, Shigematsu Y, Ariyasu H, Akamizu T, Kangawa K, Nakao K.
- Journal Title
  
  FEBS Lett.
  
  Volume: 590 Issue: 7 Pages: 992-1001
- DOI
  10.1002/1873-3468.12132
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19532, KAKENHI-PROJECT-25461385, KAKENHI-PROJECT-26461331, KAKENHI-PROJECT-16K15495
[Journal Article] Physiological significance of ghrelin revealed by studies using genetically engineered mouse models with modifications in the ghrelin system [Review]2015
- Author(s)
  Ariyasu H, Akamizu T.
- Journal Title
  
  Endocr J
  
  Volume: 62 Issue: 11 Pages: 953-963
- DOI
  10.1507/endocrj.EJ15-0361
- NAID
  130005109821
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461385
[Journal Article] Des-acyl ghrelin protects microvascular endothelial cells from oxidative stress-induced apoptosis through sirtuin 1 signaling pathway2014
- Author(s)
  Shimada T, Furuta H, Doi A, Ariyasu H, Kawashima H, Wakasaki H, Nishi M, Sasaki H, Akamizu T
- Journal Title
  
  Metabolism
  
  Volume: 63 Issue: 4 Pages: 469-474
- DOI
  10.1016/j.metabol.2013.12.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390204, KAKENHI-PROJECT-25461385
[Journal Article] Clinical effects of ghrelin on gastrointestinal involvement in patients with systemic sclerosis.2014
- Author(s)
  Ariyasu H, Iwakura H, Yukawa N, Murayama T, Yokode M, Tada H, Yoshimura K, Teramukai S, Ito T, Shimizu A, Yonezawa A, Kangawa K, Mimori T, Akamizu T.
- Journal Title
  
  Endocrine Journal
  
  Volume: 61 Pages: 735-742
- NAID
  130004443975
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461385
[Journal Article] Reduction in circulating ghrelin concentration after maturation does not affect food intake.2014
- Author(s)
  Ariyasu H, Yamada G, Iwakura H, Matsumura S, Inoue K, Kangawa K, Nakao K, Akamizu T.
- Journal Title
  
  Endocrine Journal
  
  Volume: 61 Pages: 1041-1052
- NAID
  130004704359
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461385
[Journal Article] Analysis of plasma ghrelin in patients with medium-chain acyl-CoA dehydrogenase deficiency and glutaric aciduria type II.2012
- Author(s)
  Akamizu T
- Journal Title
  
  Eur J Endocrinol
  
  Volume: 166 Issue: 2 Pages: 235-240
- DOI
  10.1530/eje-11-0785
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22126002, KAKENHI-PUBLICLY-23126510, KAKENHI-PROJECT-23791052, KAKENHI-PROJECT-23791055
[Journal Article] Transgenic mice overexpressing ghrelin or ghrelin analog2012
- Author(s)
  Ariyasu H, Nakao K, et al
- Journal Title
  
  Methods Enzymol.
  
  Volume: 514 Pages: 371-377
- DOI
  10.1016/b978-0-12-381272-8.00023-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229013, KAKENHI-PROJECT-23791055, KAKENHI-PROJECT-24390204, KAKENHI-PLANNED-22126002, KAKENHI-PUBLICLY-23126510
[Journal Article] Am Jtransgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo2012
- Author(s)
  Bando M, Iwakura H, Ariyasu H, Hosoda H,Yamada G, Hosoda K, Adachi S, Nakao K,Kangawa K, Akamizu T
- Journal Title
  
  Physiol Endocrinol Metab
  
  Volume: 302 Pages: 403-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791055
[Journal Article] Transgenic mice overexpressing ghrelin or ghrelin analog.2012
- Author(s)
  Ariyasu H, Yamada G, Iwakura H, Akamizu T, Kangawa K, Nakao K.
- Journal Title
  
  Methods Enzymol
  
  Volume: 514 Pages: 371-377
- Data Source
  KAKENHI-PROJECT-23791055
[Journal Article] Transgenic overexpression of intraislet ghrelin does not affect insulin secretion or glucose metabolism in vivo2012
- Author(s)
  Bando M, Nakao K, et al
- Journal Title
  
  Am. J. Physiol. Endocrinol. Metab.
  
  Volume: 302 Issue: 4 Pages: 403-408
- DOI
  10.1152/ajpendo.00341.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229013, KAKENHI-PROJECT-21390252, KAKENHI-PROJECT-21591190, KAKENHI-PLANNED-22126012, KAKENHI-PUBLICLY-23126510, KAKENHI-PROJECT-23791052, KAKENHI-PROJECT-23791055, KAKENHI-PROJECT-24659444
[Journal Article] Oxytocin and dopamine stimulate ghrelin secretion by theghrelin-producing cell line, MGN3-1 invitro.2011
- Author(s)
  Iwakura H, Ariyasu H, Hosoda H, Yamada G, Hosoda K, Nakao K, Kangawa K, Akamizu T.
- Journal Title
  
  Endocrinology
  
  Volume: 152 Pages: 2619-2625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791055
[Journal Article] Oxytocin and Dopamine Stimulate Ghrelin Secretion by the Ghrelin-Producing Cell Line, MGN3-1 in Vitro2011
- Author(s)
  H. Iwakura, K. Hosoda, et al
- Journal Title
  
  Endocrinology
  
  Volume: 152 (7) Issue: 7 Pages: 2619-2625
- DOI
  10.1210/en.2010-1455
- NAID
  120004397870
- URL
  http://repository.kulib.kyoto-u.ac.jp/dspace/handle/2433/158372
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22126012, KAKENHI-PUBLICLY-23126510, KAKENHI-PROJECT-23791052, KAKENHI-PROJECT-23791055
[Journal Article] A postweaning reduction in circulating ghrelin temporarily alters growth hormone (GH) responsiveness to GH-releasing hormone in male mice but does not affect somatic growth.2010
- Author(s)
  Ariyasu H
- Journal Title
  
  Endocrinology 151
  
  Pages: 1743-1750
- NAID
  120002949719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790893
[Journal Article] Generation of Transgenic Mice Over-expressing a Ghrelin Analog.2010
- Author(s)
  Yamada G, Ariyasu H , Iwakura H, Hosoda H, Akamizu T, Nakao K, Kangawa K
- Journal Title
  
  Endocrinology. 151
  
  Pages: 5935-5940
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790893
[Journal Article] Generation of transgenic mice overexpressing a ghrelin analog.2010
- Author(s)
  Yamada G, Ariyasu H, Iwakura H, Hosoda H, Akamizu T, Nakao K, Kangawa K.
- Journal Title
  
  Endocrinology
  
  Volume: 151 Pages: 5935-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790893
[Journal Article] A postweaning reduction in circulating ghrelin temporarily alters growth hormone (GH) responsiveness to GH-releasing hormone in male mice but does not affect somatic growth.2010
- Author(s)
  Ariyasu H, Iwakura H, Yamada G, Kanamoto N, Bando M, Kohno K, Sato T, Kojima M, Nakao K, Kangawa K, Akamizu T.
- Journal Title
  
  Endocrinology. 151
  
  Pages: 1743-1750
- NAID
  120002949719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790893
[Journal Article] A postweaning reduction in circulating ghrelin temporarily alters growth hormone (GH) responsiveness to GH-releasing hormone in male mice but does not affect somatic growth.2010
- Author(s)
  Ariyasu H, Iwakura H, Yamada G, Kanamoto N, Bando M, Kohno K, Sato T, Kojima M, Nakao K, Kangawa K, Akamizu T.
- Journal Title
  
  Endocrinology
  
  Volume: 151 Pages: 1743-50
- NAID
  120002949719
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790893
[Journal Article] Establishment of a novel ghrelin-producing cell line.2010
- Author(s)
  Iwakura H, Li Y, Ariyasu H, Hosoda H, Kanamoto N, Bando M, Yamada G, Hosoda K, Nakao K, Kangawa K, Akamizu T.
- Journal Title
  
  Endocrinology
  
  Volume: 151 Pages: 2940-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790893
[Journal Article] Establishment of a novel ghrelin-producing cell line.2010
- Author(s)
  Iwakura H, Li Y, Ariyasu H, Hosoda H, Kanamoto N, Bando M, Yamada G, Hosoda K, Nakao K, Kangawa K, Akamizu T.
- Journal Title
  
  Endocrinology. 151
  
  Pages: 2940-2945
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790893
[Journal Article] Ghrelin and functional dyspepsia.2010
- Author(s)
  Akamizu T, Iwakura H, Ariyasu H, Kangawa K.
- Journal Title
  
  International Journal of Peptides
  
  Volume: (電子媒体による発表)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790893
[Journal Article] A mouse model of ghrelinoma exhibited activated growth hormone-insulin-like growth factor I axis and glucose intolerance.2009
- Author(s)
  Iwakura H, Ariyasu H, Li Y, Kanamoto N, Bando M, Yamada G, Hosoda H, Hosoda K, Shimatsu A, Nakao K, Kangawa K, Akamizu T.
- Journal Title
  
  Am J Physiol Endocrinol Metab. 297
  
  Pages: 802-811
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790893
[Journal Article] Efficacy of ghrelin as a therapeutic approach for age-related physiological changes2008
- Author(s)
  Ariyasu H
- Journal Title
  
  Endocrinology 149
  
  Pages: 3722-3728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790648
[Journal Article] Repeated administration of ghrelin to patients with functional dyspepsia: its effects on food intake and appetite.2008
- Author(s)
  Akamizu T, Iwakura H, Ariyasu H, Hosoda H, Murayama T, Yokode M, Teramukai S, Seno H, Chiba T, Noma S, Nakai Y, Fukunaga M, Nakai Y, Kangawa K, FD Clinical Study Team.
- Journal Title
  
  Eur J Endocrinol 158
  
  Pages: 491-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790648
[Journal Article] the OA-THR Clinical Study Team. Effects of ghrelin treatment in patients undergoing total hip replacement for osteoarthritis: Different outcomes from studies in patients with cardiac and pulmonary cachexia.2008
- Author(s)
  Akamizu T, Iwakura H, Ariyasu H, Murayama T, Sumi E, Teramukai S, Goto K, Ohnishi E, Akiyama H, Kawanabe K, Nankaku M, Ichihashi N, Tsuboyama T, Tamai K, Kataoka M, Nakamura T, Kangawa K
- Journal Title
  
  J Am Geriatr 56
  
  Pages: 2363-2365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790648
[Journal Article] Establishment of a novel neuroblastoma mouse model.2008
- Author(s)
  Iwakura H, Ariyasu H, Kanamoto N, Hosoda K, Nakao K, Kangawa K, Akamizu T.
- Journal Title
  
  Int J Oncol. 33
  
  Pages: 1195-1199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790648
[Journal Article] Efficacy of ghrelin as a therapeutic approach for age-related physiological changes.2008
- Author(s)
  Ariyasu H, Iwakura H, Yamada G, Nakao K, Kangawa K, Akamizu T.
- Journal Title
  
  Endocrinology 149
  
  Pages: 3722-3728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790648
[Journal Article] Effects of ghrelin administration on decreased growth hormone status in obese animals.2007
- Author(s)
  Iwakura H, Akamizu T, Ariyasu H, Irako T, Hosoda K, Nakao K, Kangawa K.
- Journal Title
  
  Am J Physiol Endocrinol Metab. 293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790648
[Journal Article] Ghrelin prevents development of diabetes at adult age in streptozotocin- treated newborn rats.2006
- Author(s)
  Irako T, Akamizu T, Hosoda H, Iwakura H, Ariyasu H, Tojo K, Tajima N, Kangawa K.
- Journal Title
  
  Diabetologia. 49 (6)
  
  Pages: 1264-1273
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390269
[Journal Article] Plasma ghrelin levels in healthy elderly volunteers : the levels of acylated ghrelin in elderly females correlate positively with serum IGF-1 levels and bowel movement frequency and negatively with systolic blood pressure.2006
- Author(s)
  Akamizu T, Murayama T, Teramukai S, Miura K, Bando I, Irako T, Iwakura H, Ariyasu H, Hosoda H, Tada H, Matsuyama A, Kojima S, Wada T, Wakatsuki Y, Matsubayashi K, Kawakita T, Shimizu A, Fukushima M Yokode M, Kangawa K.
- Journal Title
  
  J Endoclinol. 188 (2)
  
  Pages: 333-344
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390269
[Journal Article] Transgenic Mice Overexpressing Des-Acyl Ghrelin Show Small Phenotype2005
- Author(s)
  Ariyasu H
- Journal Title
  
  Endocrinology 146・1
  
  Pages: 355-364
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390269
[Journal Article] Analysis of rat insulin II promoter-ghrelin transgenic mice and rat glucagons promoter-ghrelin transgenic mice.2005
- Author(s)
  Iwakura H, Hosoda K, Son C, Fujikura J, Tomita T, Noguchi M, Ariyasu H, Takaya K, Masuzaki H, Ogawa Y, Hayashi T, Inoue G, Akamizu T, Hosoda H, Kojima M, Itoh H, Toyokuni S, Kangawa K, Nakao K.
- Journal Title
  
  J Biol Chem. 280 (15)
  
  Pages: 15247-15256
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390269
[Journal Article] Transgenic Mice Overexpressing Des-Acyl Ghrelin Show Small Phenotype.2005
- Author(s)
  Ariyasu H, Takaya K, Iwakura H, Hosoda H, Akamizu T, Arai Y, Kangawa K, Nakao K.
- Journal Title
  
  Endocrinology 146 (1)
  
  Pages: 355-364
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390269
[Presentation] マウスでのグルコース刺激インスリン分泌における芳香族アミノ酸受容体GPR142とCaSRシグナルの果たす役割の検討．2018
- Author(s)
  上田陽子、岩倉浩、坂東美佳、土井麻子、有安宏之、稲葉秀文、森田修平、古田浩人、西理宏、赤水尚史
- Organizer
  第91回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K09807
[Presentation] トリプトファンによるグルコース刺激性インスリン分泌における芳香族アミノ酸受容体GPR142とCaSRシグナルの役割についての検討2018
- Author(s)
  上田陽子、岩倉浩、坂東美佳、土井麻子、有安宏之、稲葉秀文、森田修平、古田浩人、西理宏、赤水尚史
- Organizer
  第61回日本糖尿病学会年次学術
- Data Source
  KAKENHI-PROJECT-16K09807
[Presentation] Signaling　on　Terminal-Unfolded　Protein　Response　under　Endoplasmic　Reticulum　Stress in　lNS1　Cells.2018
- Author(s)
  Ishibashi　T, Morita　S, Doi　A,lwakura H, Ariyasu H, Nishi M, Furuta H, Akamizu T
- Organizer
  ADA 78th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09807
[Presentation] 1型糖尿病モデルマウス(NODマウス）におけるIRE1aを新規標的とした治療についての検討2018
- Author(s)
  森田修平、石橋達也、松野正平、岩倉浩、有安宏之、古田浩人、西理宏、赤水尚史
- Organizer
  第61回日本糖尿病学会年次学術
- Data Source
  KAKENHI-PROJECT-16K09807
[Presentation] グレグレリン過剰分泌Tgマウスの解析を通じた、中鎖脂肪酸の摂食に与える影響の解析2015
- Author(s)
  有安宏之　他8名
- Organizer
  第88回　日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ東京
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-25461385
[Presentation] グレリンの生理的及び病態生理学的意義の検討とそれに基づいたトランスレーショナルリサーチ2015
- Author(s)
  有安宏之
- Organizer
  第88回　日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ東京
- Year and Date
  2015-04-23
- Invited
- Data Source
  KAKENHI-PROJECT-25461385
[Presentation] 摂食・エネルギー代謝におけるグレリン/GHS-R系の役割の検討2012
- Author(s)
  有安宏之
- Organizer
  アディポサイエンス研究会シンポジウム
- Place of Presentation
  千里阪急ホテル
- Invited
- Data Source
  KAKENHI-PROJECT-23791055
[Presentation] 摂食・エネルギー代謝におけるグレリン/GHS-R系の役割の検討2012
- Author(s)
  有安宏之
- Organizer
  アディポサイエンス研究会シンポジウム
- Place of Presentation
  千里阪急ホテル(招待講演)
- Year and Date
  2012-08-25
- Data Source
  KAKENHI-PROJECT-23791055
[Presentation] 後天的グレリン分泌低下マウスを用いたグレリン生理的役割の検討2011
- Author(s)
  有安宏之、岩倉浩、赤水尚史、山田豪、中尾一和、寒川賢治
- Organizer
  第84回日本内分泌学会学術集会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-23791055
[Presentation] グレリン分泌低下マウスの絶食・再摂食およびストレス状況下における摂食調節についての検討2011
- Author(s)
  有安宏之、岩倉浩、勝浦五郎、後藤伸子、越智ゆかり、山下唯、赤水尚史、寒川賢治、中尾一和
- Organizer
  第38回日本神経内分泌学会
- Place of Presentation
  都道府県会館（東京都）
- Data Source
  KAKENHI-PROJECT-23791055
[Presentation] 後天的グレリン分泌低下マウスを用いたグレリン生理的役割の検討2011
- Author(s)
  有安宏之、岩倉浩、赤水尚史、山田豪、中尾一和、寒川賢治
- Organizer
  第32回日本肥満学会学術集会
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23791055
[Presentation] グレリン分泌低下マウスの絶食・再摂食およびストレス状況下における摂食調節についての検討2011
- Author(s)
  有安宏之、岩倉浩、勝浦五郎、後藤伸子、越智ゆかり、山下唯、赤水尚史、寒川賢治、中尾一和
- Organizer
  第38回日本神経内分泌学会
- Place of Presentation
  都道府県会館(東京都)
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-23791055
[Presentation] A reduction in circulating ghrelin after maturation improves diet-induced-obese phenotype2011
- Author(s)
  Hiroyuki Ariyasu, Hiroshi Iwakura,Go Yamada, Takashi Akamizu, Kenji Kangawa and Kazuwa Nakao
- Organizer
  The 29th Annual Scientific Meeting of The Obesity Society
- Place of Presentation
  The World Center Marriott in Orlando (USA)
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-23791055
[Presentation] 後天的グレリン分泌低下マウスを用いたグレリン生理的役割の検討2011
- Author(s)
  有安宏之、岩倉浩、赤水尚史、山田豪、中尾一和、寒川賢治
- Organizer
  第32回日本肥満学会学術集会
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県）
- Data Source
  KAKENHI-PROJECT-23791055
[Presentation] ヒトの糖代謝に対するグレリン投与の影響2010
- Author(s)
  有安宏之
- Organizer
  第83回日本内分泌学会学術総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-03-26
- Data Source
  KAKENHI-PROJECT-21790893
[Presentation] ヒトの糖代謝に対するグレリン投与の影響2010
- Author(s)
  有安宏之
- Organizer
  第83回日本内分泌学会学術総会
- Place of Presentation
  京都国際会議場
- Year and Date
  2010-03-26
- Data Source
  KAKENHI-PROJECT-21790893
[Presentation] 後天的グレリン分泌低下マウスにおける成長ホルモン分泌の検討2010
- Author(s)
  有安宏之, 岩倉浩, 赤水尚史, 山田豪, 中尾一和, 寒川賢治
- Organizer
  第37回日本神経内分泌学会
- Place of Presentation
  京都京都大学医学部紫蘭会館
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-21790893
[Presentation] 後天的グレリン分泌低下マウスにおける成長ホルモン分泌の検討2010
- Author(s)
  有安宏之, 岩倉浩, 赤水尚史, 山田豪, 中尾一和, 寒川賢治
- Organizer
  第37回日本神経内分泌学会
- Place of Presentation
  京都大学医学部紫蘭会館
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-21790893
[Presentation] グレリンの分泌調節と作用に関する研究2009
- Author(s)
  有安宏之
- Organizer
  第36回日本神経内分泌学会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-21790893
[Presentation] 人工股関節置換術を受けた高齢者患者の機能回復に対するグレリンの臨床効果と安全性についての検討2009
- Author(s)
  有安宏之
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  前橋文化会館
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21790893
[Presentation] 人工股関節置換術を受けた高齢者患者の機能回復に対するグレリンの臨床効果と安全性についての検討2009
- Author(s)
  有安宏之
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  前橋文化会館
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21790893
[Presentation] グレリンの分泌調節と作用に関する研究2009
- Author(s)
  有安宏之
- Organizer
  第36回日本神経内分泌学会
- Place of Presentation
  北九州国際会議場
- Year and Date
  2009-09-05
- Data Source
  KAKENHI-PROJECT-21790893
[Presentation] 加齢に伴うソマトポーズ及び食欲低下に対するグレリン有用性の研究2008
- Author(s)
  有安宏之
- Organizer
  第81回日本内分泌学会学術総会
- Place of Presentation
  青森市文化会館
- Year and Date
  2008-05-18
- Data Source
  KAKENHI-PROJECT-19790648
[Presentation] 加齢に伴うソマトポーズ及び食欲低下に対するグレリン有用性の研究2007
- Author(s)
  有安宏之
- Organizer
  第34回日本神経内分泌学会
- Place of Presentation
  群馬県前橋市
- Year and Date
  2007-08-04
- Data Source
  KAKENHI-PROJECT-19790648
[Presentation] 加齢に伴うソマトポーズ及び食欲低下に対するグレリン有用性の研究2007
- Author(s)
  有安宏之
- Organizer
  第34回日本神経内分泌学会
- Place of Presentation
  群馬県前橋市
- Data Source
  KAKENHI-PROJECT-19790648
[Presentation] グレリンの生理的及び病態生理学的意義の検討とそれに基づいたトランスレーショナルリサーチ
- Author(s)
  有安宏之
- Organizer
  第88回日本内分泌学会
- Place of Presentation
  ホテルニューオータニ東京
- Year and Date
  2014-04-23 – 2014-04-25
- Invited
- Data Source
  KAKENHI-PROJECT-25461385
[Presentation] グレリン過剰分泌Tgマウスの解析を通じた、中鎖脂肪酸の摂食に与える影響の解析
- Author(s)
  有安宏之、竹島健、浦木進丞、川嶋弘道、古田浩人、西理宏、中尾一和、寒川賢治、赤水尚史
- Organizer
  第88回日本内分泌学会
- Place of Presentation
  ホテルニューオータニ東京
- Year and Date
  2014-04-23 – 2014-04-25
- Data Source
  KAKENHI-PROJECT-25461385

1. AKAMIZU Takashi (20231813)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. IWAKURA Hiroshi (20378615)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
3. IRAKO Taiga (40402870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. KANGAWA Kenji (00112417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 稲葉秀文

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 細田公則

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中尾一和

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 坂東美佳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ariyasu Hiroyuki 有安 宏之

ARIYASU Hiroyuki 有安 宏之

Research Projects

Research Products

Co-Researchers

Investigation of ghrelin effects on gut hormones and glucose metabolism using transgenic mice

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Physiological roles of free fatty acids in the regulation of food intakePrincipal Investigator

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Physiological Roles of circulating ghrelin on food intake and energy homeostasisPrincipal Investigator

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The Analysis of Physiological Roles of circulating ghrelinPrincipal Investigator

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Generation of a transgenic mouse that expressing human diphtheria toxin receptor cDNA under the control of the transcription regulatory regions of ghrelinPrincipal Investigator

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Effect of ghrelin on pancreas beta cells and diabetic animal models

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[Journal Article] Differential role of GPR142 in tryptophan-mediated enhancement of insulin secretion in obese and lean mice2018

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[Journal Article] Thyrotoxicosis and Adrenocortical Hormone Deficiency During Immune-checkpoint Inhibitor Treatment for Malignant Melanoma.2018

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[Journal Article] Imbalanced Expression of IGF2 and PCSK4 Is Associated With Overproduction of Big IGF2 in SFT With NICTH: A Pilot Study2018

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[Journal Article] Reduced Expression of Mismatch Repair Genes MSH6/MSH2 Directly Promotes Pituitary Tumor Growth via the ATR-Chk1 Pathway2018

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[Journal Article] Predominant Improvement of Alpha Cell Function after Steroid Therapy in a Patient with Autoimmune Pancreatitis: Case Report2018

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[Journal Article] Fulminant Type 1 Diabetes Mellitus Accompanied by Positive Conversion of Anti-insulin Antibody after the Administration of Anti-CTLA-4 Antibody Following the Discontinuation of Anti-PD-1 Antibody2018

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[Journal Article] High incorporation of long-chain fatty acids contributes to the efficient production of acylated ghrelin in ghrelin-producing cells.2016

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[Journal Article] Comprehensive Profiling of GPCR Expression in Ghrelin-producing Cells.2016

Author(s)

Ariyasu Hiroyuki 有安宏之

ARIYASU Hiroyuki 有安宏之