TAMURA Hiroshi 田村博史

Researcher Number	50379947
Other IDs
Affiliation *help	2015 – 2018 : 山口大学, 医学(系)研究科(研究院), 准教授 2016 – 2018 : 山口大学, 大学院医学系研究科, 准教授 2013 : 山口大学, 医学(系)研究科(研究院), 准教授 2010 – 2011 : 山口大学, 医学部附属病院, 准教授 2010 : 山口大学, 医学部付属病院, 准教授 2008 – 2009 : 山口大学, 医学部附属病院, 講師 2005 – 2006 : 山口大学, 医学部附属病院, 講師
Review Section/Research Field	Principal Investigator Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator 活性酸素 / メラトニン / 卵子 / 加齢 / 卵胞 / 体外受精胚移植 / アポトーシス / 酸化ストレス / 卵胞閉鎖 / 卵細胞 … More Except Principal Investigator PGF2α / プロゲステロン / 活性酸素 / 生殖医学 / 黄体 / 黄体退縮 Less

メラトニンは卵胞閉鎖を抑制して発育卵胞数、排卵数を増加させるPrincipal InvestigatorOngoing
- Principal Investigator
  
  田村博史
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University
Long-term melatonin treatment for the prevention of ovarian aging.Principal Investigator
- Principal Investigator
  
  TAMURA Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University
Melatonin protects oocyte and granulosa cellsfrom reactive oxygen species during ovulation process within the folliclePrincipal Investigator
- Principal Investigator
  
  TAMURA Hiroshi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University
The role of reactive oxygen species as bioactive substances in the regulation of luteal function
- Principal Investigator
  
  SUGINO Norihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University
卵の質の低下に関与する因子の解明Principal Investigator
- Principal Investigator
  
  田村博史
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamaguchi University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008

All Journal Article Presentation Book

[Book] 産科と婦人科生殖機能調節の新しい視点メラトニンの卵巣機能調節2010
- Author(s)
  田村博史
- Total Pages
  7
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-21592099
[Book] Characterization of "thin" endometrium and treatment with vitamin E.(Maruo T, Mardon H, Stewart C, eds.)2008
- Author(s)
  Sugino N, Miwa I, Tamura H, 他2名
- Publisher
  In : Translational research in uterine biology.
- Data Source
  KAKENHI-PROJECT-20591918
[Journal Article] Long term melatonin treatment delays ovarian aging2017
- Author(s)
  Tamura H, Kawamoto M, Sato S, Tamura I, Maekawa R, Taketani T, Aasada H, Takaki E, Nakai A, Reiter RJ, Sugino N.
- Journal Title
  
  J Pineal Res.
  
  Volume : 印刷中
- DOI
  10.1111/jpi.12381
- Peer Reviewed / Open Access / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04706, KAKENHI-PROJECT-15K10720, KAKENHI-PROJECT-16K11091
[Journal Article] Melatonin protects the integrity of granulosa cells by reducing oxidative stress in nuclei, mitochondria, and plasma membranes in mice.2015
- Author(s)
  Tanabe M, Tamura H, Taketani T, Okada M, Lee L, Tamura I, Maekawa R, Asada H, Yamagata Y, Sugino N.
- Journal Title
  
  J Reprod Dev.
  
  Volume : 61 Pages : 35-41
- DOI
  10.1262/jrd.2014-105
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462559
[Journal Article] Melatonin and female reproduction2014
- Author(s)
  Tamura H, Takasaki A, Taketani T, Tanabe M, Lee L, Tamura I, Maekawa R, Aasada H, Yamagata Y, Sugino N.
- Journal Title
  
  J Obstet Gynaecol Res
  
  Volume : 40 Pages : 1-11
- DOI
  10.1111/jog.12177
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462559
[Journal Article] The role of melatonin as an antioxidant in the follicle2012
- Author(s)
  Hiroshi Tamura
- Journal Title
  
  Journal of Ovarian Research
  
  Volume : (In press)
- DOI
  10.1186/1757-2215-5-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592099
[Journal Article] The role of melatonin as an antioxidant in the fbllicle2012
- Author(s)
  Tamura H, Takasaki A, Taketani T, Tanabe M, Kizuka F, Lee L, Tamura I, Maekawa R, Asada H, Yamagata Y, Sugino
- Journal Title
  
  N. J Ov Res
  
  Volume : (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592099
[Journal Article] Luteal blood flow in patients undergoing GnRH agonist long protocol2011
- Author(s)
  Takasaki A, Tamura I, Kizuka F, Lee L, Maekawa R, Asada H, Taketani T, Tamura H, Shimamura K, Morioka H, Sugino N
- Journal Title
  
  J Ovarian Res
  
  Volume : 4 Pages : 2-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592099
[Journal Article] Protective role ofmelatonin in progesterone production by human luteal cells2011
- Author(s)
  Taketani T, Tamura H, Takasaki A, Lee L, Kizuka F, Tamura I, Taniguchi K, Maekawa R, Asada H, Shimamura K, Reiter RJ
- Journal Title
  
  Sugino N. J Pineal Res
  
  Volume : 51 Pages : 207-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592099
[Journal Article] Luteal blood flow in patients undergoing GnRH agonist long protocol.2011
- Author(s)
  Takasaki A, Tamura H, Sugino N, 他8名
- Journal Title
  
  Journal of Ovarian Research 4:2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591918
[Journal Article] Protective role of melatonin in progesterone production by human luteal cells.2011
- Author(s)
  Taketani T, Tamura H, Sugino N, 他9名
- Journal Title
  
  Journal of Pineal Research in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591918
[Journal Article] Differential effects of progesterone on COX-2 and Mn-SOD expressions are associated with histone acetylation status ofthe promoter region in human endometrial stromal cells2011
- Author(s)
  Tamura I, Taketani T, Lee L, Kizuka F, Taniguchi K, Maekawa R, Asada H, Tamura H
- Journal Title
  
  Sugino N. J Clin Endocrinol Metab
  
  Volume : 96 Pages : 1073-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592099
[Journal Article] Progesterone increases manganese superoxide dismutase expression via a cAMP-dependent signaling mediated by non-canonical Wnt5a pathway in human endometrial stromal cells.2010
- Author(s)
  Matsuoka A, Tamura H, Sugino N, 他7名
- Journal Title
  
  The Journal of Clinical Endocrinology and Metabolism 95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591918
[Journal Article] Prostaglandin F2α (PGF2α) stimulates PTGS2 expression and PGF2α synthesis through NFKB activation via reactive oxygen species in the corpus luteum of pseudopregnant rats.2010
- Author(s)
  Taniguchi K, Tamura H, Sugino N, 他7名
- Journal Title
  
  Reproduction 140
  
  Pages : 885-892
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591918
[Journal Article] 生殖機能調節の新しい視点10.メラトニンの卵巣機能調節2010
- Author(s)
  田村博史、杉野法広
- Journal Title
  
  産科と婦人科
  
  Volume : 第77巻3号 Pages : 310-316
- Data Source
  KAKENHI-PROJECT-21592099
[Journal Article] Progesterone increases manganese superoxide dismutase expression via a cAMP-dependent signaling mediated by noncanonical Wnt5a pathway in human endometrial stromal cells2010
- Author(s)
  Matsuoka A, Kizuka F, Lee L, Tamura I, Taniguchi K, Asada H, Taketani T, Tamura H
- Journal Title
  
  Sugino N. J Clin Endocrinol Metab
  
  Volume : 95 Pages : 291-299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592099
[Journal Article] Melatonin and the ovary ; physiological and pathophysiological implications.2009
- Author(s)
  Tamura H, Sugino N, (他5名)
- Journal Title
  
  Fertility and sterility 92
  
  Pages : 328-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591918
[Journal Article] Melatonin and the ovary ; physiological and pathophysiological implications.2009
- Author(s)
  HIROSHI TAMURA
- Journal Title
  
  Fertil Steril 92
  
  Pages : 328-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592099
[Journal Article] 卵過程におけるメラトニンの防御的役割-メラトニンは卵胞内で卵と顆粒膜細胞を酸化ストレスから護る-2009
- Author(s)
  田村博史
- Journal Title
  
  日本産科婦人科学会誌
  
  Volume : 第61巻第10号 Pages : 1925-1934
- Data Source
  KAKENHI-PROJECT-21592099
[Journal Article] Combination of melatonin and a peroxisome proliferator-activated receptor-gamma agonist induces apoptosis in a breast cancer cell line2009
- Author(s)
  Korkmaz A, Tamura H, Manchester LC, Ogden GB, Tan DX
- Journal Title
  
  Reiter RJ. J Pineal Res
  
  Volume : 46 Pages : 115-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592099
[Journal Article] Melatonin and the ovary ; physiological and pathophysiological implications.[ Review article]2009
- Author(s)
  Tamura H, Nakamura Y, Korkmaz A, Manchester LC, Tan DX, Norihiro S
- Journal Title
  
  Reiter RJ. Fertil Steril
  
  Volume : 92 Pages : 328-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592099
[Journal Article] Different changes in resistance index between uterine artery and uterineradial artery during pregnancy.2008
- Author(s)
  Tamura H, Sugino N, (他8名)
- Journal Title
  
  Human Reproduction 23
  
  Pages : 285-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591918
[Journal Article] Melatonin treatment in peri-and postmenopausal women elevates serum high-dendity lipoprotein cholesterol levels without influencing total cholesterol levels.2008
- Author(s)
  Tamura H, Sugino N, (他5名)
- Journal Title
  
  Journal of Pineal Research 45
  
  Pages : 101-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591918
[Journal Article] Changes in blood flow impedance of the human corpus luteum throughout the luteal phase and during early pregnancy.2008
- Author(s)
  Tamura H, Sugino N, (他4名)
- Journal Title
  
  Fertility and sterility 90
  
  Pages : 2334-2339
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591918
[Presentation] Long-term melatonin treatment for the prevention of ovarian aging.2016
- Author(s)
  Hiroshi Tamura, Toshiaki Taketani, Hiromi Asada, Norihiro Sugino
- Organizer
  European Society of Human Reproduction and Embryology
- Place of Presentation
  HELSINKI, Finland
- Year and Date
  2016-07-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11091
[Presentation] Potential mechanism by which glucose regulates decidualization in human endometrial stromal cells2016
- Author(s)
  Hiroshi Tamura, Norihiro Sugino
- Organizer
  American Society for Reproduction Medicine Scientific Congress
- Place of Presentation
  Salt Lake City, Utah, USA
- Year and Date
  2016-10-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11091
[Presentation] メラトニンの卵巣加齢に対する予防効果2016
- Author(s)
  河本舞、田村博史、品川征大、杉野法広
- Organizer
  第57回日本卵子学会
- Place of Presentation
  朱鷺メッセ新潟コンベンションセンター、新潟県新潟市
- Year and Date
  2016-05-14
- Data Source
  KAKENHI-PROJECT-16K11091
[Presentation] メラトニン長期投与によるマウス卵巣加齢の予防効果2015
- Author(s)
  田村博史、河本　舞、品川征大、岡田真紀、澁谷文恵、竹谷俊明、浅田裕美、杉野法広
- Organizer
  第15回日本抗加齢医学会学術総会
- Place of Presentation
  福岡国際会議場（福岡県福岡市）
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] メラトニン長期投与によるマウス卵巣加齢の予防効果2015
- Author(s)
  田村博史、河本　舞、品川征大、岡田真紀、澁谷文恵、竹谷俊明、浅田裕美、杉野法広
- Organizer
  第33回日本受精着床学会学術総会
- Place of Presentation
  TFTホール（東京都江東区）
- Year and Date
  2015-11-26
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] Changes in histone modification,DNA methylation and C/EBPb binding of the Cyp11a1 promoter region in rat granulosa cells undergoing luteinization during ovulation.2015
- Author(s)
  M.Okada, R.Maekawa, H.Tamura, N.Sugino
- Organizer
  48th Annual Meeting of the Society for the Study of Reproduction
- Place of Presentation
  Puerto Rico Convention Center（プエルトリコ　サンファン）
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] Tissue-Specific expression of estrogen receptor 1　IS regulated by DNA methylation in A T-DMR （tissuedep endent and differentially methylated region）.2015
- Author(s)
  H. Asada, M.Okada, H.Tamura, N.Sugino
- Organizer
  The Annual Meeting of the American Sciety for Reproductive Medicine, ASRM2015
- Place of Presentation
  Baltimore Convention Center（USA）
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] メラトニン長期投与によるマウス卵巣加齢の予防効果2014
- Author(s)
  田村博史，田邊学，岡田真紀、田村功，浅田裕美，山縣芳明，杉野法広
- Organizer
  第66回日本産科婦人科学会学術講演会
- Place of Presentation
  東京国際フォーラム（東京都）
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] メラトニン長期投与によるマウス卵巣加齢の予防効果2014
- Author(s)
  田村博史，田邊学，岡田真紀、田村功，浅田裕美，山縣芳明，杉野法広
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場（福岡県）
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] メラトニン長期投与によるマウス卵巣加齢の予防効果2013
- Author(s)
  田村博史，田邊学，岡田真紀、田村功，浅田裕美，山縣芳明，杉野法広
- Organizer
  第31回日本受精着床学会総会学術講演会
- Place of Presentation
  別府国際コンベンションセンター（大分県）
- Data Source
  KAKENHI-PROJECT-25462559
[Presentation] 松果体ホルモンであるメラトニンは卵胞内で卵や顆粒膜細胞を護る2011
- Author(s)
  田村博史
- Organizer
  第84回日本内分泌学会学術総会シンポジウム9
- Place of Presentation
  神戸国際会議場(神戸市)
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-21592099
[Presentation] 松果体ホルモンであるメラトニンは卵胞内で卵や穎粒膜細胞を護るシンポジウム9「生殖機能の中枢性調節:最近の知見」2011
- Author(s)
  田村博史
- Organizer
  第84回日本内分泌学会学術総会
- Place of Presentation
  神戸市神戸国際会議場
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-21592099
[Presentation] -メラトニン研究の最近の進歩と医療への応用-パネルディスカッション『私のメラトニン使用経験から』2011
- Author(s)
  田村博史
- Organizer
  第3回抗加齢内分泌研究会学術集会
- Place of Presentation
  横浜市鶴見大学会館
- Year and Date
  2011-09-04
- Data Source
  KAKENHI-PROJECT-21592099
[Presentation] ヒト子宮内膜間質細胞(ESC)の脱落膜化によって誘導されるIGFBP-1, prolactin (PRL)遺伝子発現におけるepigenetic調節機構2010
- Author(s)
  田村功、田村博史、杉野法広, 他7名
- Organizer
  第15回日本生殖内分泌学会学術総会
- Place of Presentation
  千里ライフサイエンスセンター
- Data Source
  KAKENHI-PROJECT-20591918
[Presentation] ラット顆粒膜細胞の黄体化におけるSteroidogenic Acute Regulatory (StAR) 遺伝子発現のepigenetic制御の関与2010
- Author(s)
  李理華、田村博史、杉野法広, 他7名
- Organizer
  第15回日本生殖内分泌学会学術総会
- Place of Presentation
  千里ライフサイエンスセンター
- Year and Date
  2010-11-21
- Data Source
  KAKENHI-PROJECT-20591918
[Presentation] Influence of oxidative stress on oocyte quality and protective role of melatonin as an antioxidant2010
- Author(s)
  Hiroshi Tamura
- Organizer
  IFFS 2010 20^<th> World Congress on Fertility and Sterility
- Place of Presentation
  Munich, Germany
- Data Source
  KAKENHI-PROJECT-21592099
[Presentation] DNA methylation and histone acethylation status in the promoter region of insulin-like growth factor-binding protein in human endometrial stromal cells.2010
- Author(s)
  R.Maekawa, I.Tamura, N.Sugino
- Organizer
  57th Annual meeting of Society for Gynecologic Investigation
- Place of Presentation
  Orlando, Florida, USA
- Data Source
  KAKENHI-PROJECT-20591918
[Presentation] Influence of oxidative stress on oocyte quality and protective role of melatonin as an antioxidant2010
- Author(s)
  Hiroshi Tamura, Toshiaki Taketani, Akihisa Takasaki, Norihiro Sugino
- Organizer
  IFFS 2010 20^<th> World Congress on Fertility and Sterility
- Place of Presentation
  Munich, Germany
- Data Source
  KAKENHI-PROJECT-21592099
[Presentation] Differential modification of progesterone in TNFa-induced COX-2 and Mn-SOD expression in human endometrial stromal cells.2009
- Author(s)
  H.Tamura, N.Sugino
- Organizer
  The 25th Annual Meeting of the European Society of Human Reproduction and Embryology
- Place of Presentation
  Netherlands
- Data Source
  KAKENHI-PROJECT-20591918
[Presentation] Differential modification of progesterone in TNFa-induced COX-2 and Mn-SOD expression in human endometrial stromal cells.2009
- Author(s)
  I.Tamura, N.Sugino, (他3名)
- Organizer
  42th Annual Meting of the Society for the Study on Reproduction
- Place of Presentation
  Pittsburgh, USA
- Data Source
  KAKENHI-PROJECT-20591918
[Presentation] 松果体ホルモンメラトニンと生殖2009
- Author(s)
  田村博史
- Organizer
  第27回内分泌代謝学サマーセミナー
- Place of Presentation
  福井県三国観光ホテル
- Year and Date
  2009-07-16
- Data Source
  KAKENHI-PROJECT-21592099
[Presentation] 松果体ホルモンメラトニンと生殖2009
- Author(s)
  田村博史
- Organizer
  第82回日本内分泌学会研究奨励賞受賞講演
- Place of Presentation
  前橋市群馬県民会館
- Year and Date
  2009-04-25
- Data Source
  KAKENHI-PROJECT-21592099
[Presentation] 排卵過程におけるメラトニンの防御的役割-メラトニンは卵胞内で卵と顆粒膜細胞を酸化ストレスから護る-2009
- Author(s)
  田村博史
- Organizer
  第61回日本産科婦人科学会学術講演会シンポジウム2『中枢神経関連生理活性物質の生殖機能へのかかわり』
- Place of Presentation
  京都市国立京都国際会館
- Year and Date
  2009-04-04
- Data Source
  KAKENHI-PROJECT-21592099
[Presentation] Melatonin protects oocyte and granulosa cells from reactive oxygen species(ROS) during the ovulatory process2009
- Author(s)
  Hiroshi Tamura, Toshiaki Taketani, Norihiro Sugino
- Organizer
  XI Congress of the European Biological Rhythms Society
- Place of Presentation
  Strasbourg, France
- Data Source
  KAKENHI-PROJECT-21592099
[Presentation] Melatonin protects oocyte and granulosa cells from reactive oxygen species during the ovulatory process.2009
- Author(s)
  H Tamura, T.Taketani, N.Sugino
- Organizer
  11th Congress of the European Biological Rhythms Society
- Place of Presentation
  Strasbourg, France
- Data Source
  KAKENHI-PROJECT-20591918

1. TAKETANI Toshiaki (70464328)

# of Collaborated Projects : 2results

# of Collaborated Products : 9results
2. SUGINO Norihiro (10263782)

# of Collaborated Projects : 1results

# of Collaborated Products : 15results
3. ASADA Hiromi (90526906)

# of Collaborated Projects : 1results

# of Collaborated Products : 8results
4. 中井彰

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
5. 佐藤俊

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

TAMURA Hiroshi 田村 博史

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メラトニンは卵胞閉鎖を抑制して発育卵胞数、排卵数を増加させるPrincipal InvestigatorOngoing

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Long-term melatonin treatment for the prevention of ovarian aging.Principal Investigator

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Melatonin protects oocyte and granulosa cellsfrom reactive oxygen species during ovulation process within the folliclePrincipal Investigator

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The role of reactive oxygen species as bioactive substances in the regulation of luteal function

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卵の質の低下に関与する因子の解明Principal Investigator

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[Book] 産科と婦人科 生殖機能調節の新しい視点 メラトニンの卵巣機能調節2010

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[Book] Characterization of "thin" endometrium and treatment with vitamin E.(Maruo T, Mardon H, Stewart C, eds.)2008

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[Journal Article] Long term melatonin treatment delays ovarian aging2017

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[Journal Article] Melatonin protects the integrity of granulosa cells by reducing oxidative stress in nuclei, mitochondria, and plasma membranes in mice.2015

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[Journal Article] Melatonin and female reproduction2014

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[Journal Article] The role of melatonin as an antioxidant in the follicle2012

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[Journal Article] The role of melatonin as an antioxidant in the fbllicle2012

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[Journal Article] Luteal blood flow in patients undergoing GnRH agonist long protocol2011

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[Journal Article] Protective role ofmelatonin in progesterone production by human luteal cells2011

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[Journal Article] Luteal blood flow in patients undergoing GnRH agonist long protocol.2011

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[Journal Article] Protective role of melatonin in progesterone production by human luteal cells.2011

TAMURA Hiroshi 田村博史

[Book] 産科と婦人科生殖機能調節の新しい視点メラトニンの卵巣機能調節2010