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Shimada Miho  嶋田 美穂

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嶋田 美穂  シマダ ミホ

SHIMADA Miho  嶋田 美穂

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Researcher Number 50383287
Other IDs
Affiliation (Current) 2025: 横浜市立大学, 医学研究科, 客員講師
Affiliation (based on the past Project Information) *help 2020 – 2023: 横浜市立大学, 医学研究科, 客員講師
2019: 横浜市立大学, 医学研究科, 特任講師
2006 – 2007: 埼玉医科大学, 医学部, 助教
2005 – 2006: 埼玉医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Basic Section 43010:Molecular biology-related / Molecular biology
Except Principal Investigator
Molecular biology / Biological Sciences
Keywords
Principal Investigator
核内局在 / クロマチン / 遺伝子発現制御 / TAD形成 / インシュレーター / CTCF結合 / クロマチン構造変換 / カラムクロマトグラフィー / 組換え体たんぱく質 / インスレーター … More / メディエーター / 遺伝子発現 / クロマチン構造 / 二本鎖RNA / クロマチン構造変化 / in vitro転写実験系 / c-fos遺伝子 / 転写制御 / コアクチベーター … More
Except Principal Investigator
expression regulation / transcription / phosphorylation / chromatin / キナーゼ / 遺伝子 / 発現制御 / 転写 / リン酸化 / クロマチン / 一本鎖RNA / 基本転写因子 / バキュロウイルス / ガン遺伝子 / 転写調節 Less
  • Research Projects

    (4 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (2 People)
  •  転写と共役した遺伝子座の核内局在ダイナミクスの解析Principal Investigator

    • Principal Investigator
      嶋田 美穂
    • Project Period (FY)
      2018 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43010:Molecular biology-related
    • Research Institution
      Yokohama City University
  •  Analysis of regulatory mechanisms of chromatin phosphorylation by kinases

    • Principal Investigator
      HISATAKE Koji
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      University of Tsukuba
  •  NF複合体によるc-fos遺伝子のクロマチン修飾と発現制御

    • Principal Investigator
      HISATAKE Koji
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      University of Tsukuba
  •  新規コアクチベーターによるmRNA生成での多段階調節機構の解明Principal Investigator

    • Principal Investigator
      嶋田 美穂
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Molecular biology
    • Research Institution
      Saitama Medical University

All 2024 2023 2022 2021 2020 2019 2007 2006 2005

All Journal Article Presentation

  • [Journal Article] Hyposecretion of cervical MUC5B is related to preterm birth in pregnant women after cervical excisional surgery2024

    • Author(s)
      Ueda Yusuke、Mogami Haruta、Chigusa Yoshitsugu、Kawamura Yosuke、Inohaya Asako、Takakura Masahito、Yasuda Eriko、Matsuzaka Yu、Shimada Miho、Ito Shinji、Morita Satoshi、Mandai Masaki、Kondoh Eiji
    • Journal Title

      American Journal of Reproductive Immunology

      Volume: 91 Issue: 3

    • DOI

      10.1111/aji.13832

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06482, KAKENHI-PROJECT-21K09540
  • [Journal Article] 2種類の子宮内細菌叢検査による臨床的有用性の後方視的比較検討2024

    • Author(s)
      土山史佳, 大見健二, 黒田雅子, 曽根弥栄子, 渡邉芳明, 範田正輝, 瀬川将史, 田中克, 荒井渉, 嶋田美穂, 大久保毅, 瀬川智也
    • Journal Title

      日本受精着床学会雑誌

      Volume: 41

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06482
  • [Journal Article] Vaginal Microbiota and Pregnancy Outcomes of Patients with Conization Histories2023

    • Author(s)
      Hashiramoto Shin、Kinjo Tadatsugu、Tanaka Suguru E.、Arai Wataru、Shimada Miho、Ashikawa Kyota、Sakuraba Yoshiyuki、Yuji Oki、Yara Nana、Kinjyo Yoshino、Chinen Yukiko、Nagai Yutaka、Mekaru Keiko、Aoki Yoichi
    • Journal Title

      Journal of Women's Health

      Volume: 32 Issue: 3 Pages: 375-384

    • DOI

      10.1089/jwh.2022.0440

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06482
  • [Journal Article] The KAT-Score is a useful indicator for predicting ongoing pregnancy in mosaic risk assessment in PGT-A: a prospective study with single vitrified-warmed blastocyst transfer2023

    • Author(s)
      Harada Y、Fukunaga E、Maeda T、Ikeda M、Shiba R、Okano S、Kinutani M、Tanaka S、Shimada M、Sakuraba Y
    • Journal Title

      Human Reproduction

      Volume: 38 Issue: Supplement_1

    • DOI

      10.1093/humrep/dead093.490

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06482
  • [Journal Article] Two target gene activation pathways for orphan ERR nuclear receptors2023

    • Author(s)
      Nakadai Tomoyoshi、Shimada Miho、Ito Keiichi、Cevher Murat Alper、Chu Chi-Shuen、Kumegawa Kohei、Maruyama Reo、Malik Sohail、Roeder Robert G
    • Journal Title

      Cell Research

      Volume: 33 Issue: 2 Pages: 165-183

    • DOI

      10.1038/s41422-022-00774-z

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06482, KAKENHI-PROJECT-22K07161
  • [Journal Article] The 3′ Pol II pausing at replication-dependent histone genes is regulated by Mediator through Cajal bodies’ association with histone locus bodies2022

    • Author(s)
      Suzuki Hidefumi、Abe Ryota、Shimada Miho、Hirose Tomonori、Hirose Hiroko、Noguchi Keisuke、Ike Yoko、Yasui Nanami、Furugori Kazuki、Yamaguchi Yuki、Toyoda Atsushi、Suzuki Yutaka、Yamamoto Tatsuro、Saitoh Noriko、Sato Shigeo、Tomomori-Sato Chieri、Conaway Ronald C.、Conaway Joan W.、Takahashi Hidehisa
    • Journal Title

      Nature Communications

      Volume: 13 Issue: 1 Pages: 2905-2905

    • DOI

      10.1038/s41467-022-30632-w

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06482, KAKENHI-PROJECT-22K19466, KAKENHI-ORGANIZER-21H05158, KAKENHI-PLANNED-21H05159, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H03182, KAKENHI-PROJECT-20H03520, KAKENHI-PROJECT-21H02405, KAKENHI-PROJECT-20K06893, KAKENHI-PROJECT-21K19356, KAKENHI-PLANNED-18H05531
  • [Journal Article] Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts2021

    • Author(s)
      Calvin Jon A Leonen, Miho Shimada, Caroline E Weller, Tomoyoshi Nakadai, Peter L Hsu, Elizabeth L Tyson, Arpit Mishra, Patrick Mm Shelton, Martin Sadilek, R David Hawkins, Ning Zheng, Robert G Roeder, Champak Chatterjee
    • Journal Title

      eLife

      Volume: 8

    • DOI

      10.7554/elife.67952

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07651, KAKENHI-PROJECT-19K06482
  • [Journal Article] Shank2 Binds to aPKC and Controls Tight Junction Formation with Rap1 Signaling during Establishment of Epithelial Cell Polarity2020

    • Author(s)
      Sasaki Kazunori、Kojitani Noriko、Hirose Hiroko、Yoshihama Yohei、Suzuki Hidefumi、Shimada Miho、Takayanagi Ayumi、Yamashita Akio、Nakaya Masa-aki、Hirano Hisashi、Takahashi Hidehisa、Ohno Shigeo
    • Journal Title

      Cell Reports

      Volume: 31 Issue: 1 Pages: 107407-107407

    • DOI

      10.1016/j.celrep.2020.02.088

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K06482, KAKENHI-PROJECT-19K22601, KAKENHI-PROJECT-20K15718, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-19K22401, KAKENHI-PROJECT-20H03438
  • [Journal Article] Gene-Specific H1 Eviction through a Transcriptional Activator→p300→NAP1→H1 Pathway2019

    • Author(s)
      Shimada Miho、Chen Wei-Yi、Nakadai Tomoyoshi、Onikubo Takashi、Guermah Mohamed、Rhodes Daniela、Roeder Robert G.
    • Journal Title

      Molecular Cell

      Volume: 74 Issue: 2 Pages: 268-283.e5

    • DOI

      10.1016/j.molcel.2019.02.016

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K06482
  • [Journal Article] c-fos遺伝子の転写誘導時に起こるヒストンH3リン酸化の誘導機構2007

    • Author(s)
      嶋田美穂、中太智義、福田綾、久武幸司
    • Journal Title

      実験医学 25

      Pages: 85-89

    • Data Source
      KAKENHI-PROJECT-18570164
  • [Journal Article] Regulatory mechanism of histone H3 phosphorylation upon c-fos gene induction2007

    • Author(s)
      Miho Shimada, Tomoyoshi Nakadai, Aya Fukuda, Koji Hisatake
    • Journal Title

      Jikkennigaku 25

      Pages: 85-89

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570164
  • [Journal Article] The fission yeast protein, kerlp, is an ortholog of RNA polymerase I subunit A14 in Saccharomyces cerevisiae, and is required for stable association of Rrn3p and RPA21 in Pol I.2005

    • Author(s)
      Imazawa Y, Hisatake K, Mitsuzawa H, Matsumoto M, Tsukui T, Nakagawa K, Nakadai T, Shimada M, Ishihama A, Nogi Y
    • Journal Title

      J.Biol.Chem 280・12

      Pages: 11467-11474

    • Data Source
      KAKENHI-PROJECT-17770146
  • [Journal Article] The fission yeast protein, Ker1p, is an ortholog of RNA polymerase I subunit A14 in Saccharomyces cerevisiae, and is required for stable association of Rrn3p and RPA21 in Pol I.2005

    • Author(s)
      Imazawa Y, Hisatake K, Mitsuzawa H, Matsumoto M, Tsukui T, Nakagawa K, Nakadai T, Shimada M, Ishihama A, Nogi Y
    • Journal Title

      J.Biol.Chem. 280・12

      Pages: 11467-11474

    • Data Source
      KAKENHI-PROJECT-17054037
  • [Presentation] ART妊娠後の流産と子宮内フローラの関連性について2023

    • Author(s)
      坂井和貴、長谷川麻理、野手健造、杉野明香、田中克、荒井渉、芦川享大、嶋田美穂、伊木朱有美、鍋田基生
    • Organizer
      第26回日本IVF学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K06482
  • [Presentation] ゲノム配列解析による子宮頸がん再発モニタリングのためのリキッドバイオプシー2023

    • Author(s)
      今西規、鈴木優、三上幹雄、嶋田美穂
    • Organizer
      日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K06482
  • [Presentation] 不妊症治療における漢方薬内服の膣内フローラ(細菌叢)改善効果の検討2023

    • Author(s)
      岡村 麻子、嶋田 美穂
    • Organizer
      産婦人科漢方研究会学術集会
    • Data Source
      KAKENHI-PROJECT-19K06482
  • [Presentation] 周産期予後と子宮内フローラの関連性について2023

    • Author(s)
      野手健造、長谷川麻理、河知美佳、坂井和貴、杉野明香、田中克、荒井渉、芦川享大、嶋田美穂、伊木朱有美、鍋田基生
    • Organizer
      第68回日本生殖医学会学術講演会・総会
    • Data Source
      KAKENHI-PROJECT-19K06482
  • [Presentation] 子宮内細菌叢と流産率の関連性の検討2023

    • Author(s)
      長谷川麻理、河知美佳、野手健造、坂井和貴、杉野明香、田中克、荒井渉、芦川享大、嶋田美穂、伊木朱有美、鍋田基生
    • Organizer
      第41回日本受精学会総会・学術講演会
    • Data Source
      KAKENHI-PROJECT-19K06482
  • [Presentation] クロマチン構造変換を伴った遺伝子発現制御機構2019

    • Author(s)
      嶋田美穂
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-19K06482
  • [Presentation] c-fos遺伝子の転写調節機構の解析2007

    • Author(s)
      福田綾、中太智義、嶋田美穂、久武幸司
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-12
    • Data Source
      KAKENHI-PROJECT-18570164
  • [Presentation] Mechanisms of histone H3 phosphorylation on the c-fos promoter2007

    • Author(s)
      Shimada M, Nakadai T, Fukuda A, Nogi Y, Hisatake K
    • Organizer
      Mechanisms of Eukaryotic Transcription, Cold Spring Harbor
    • Place of Presentation
      New York
    • Year and Date
      2007-08-31
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570164
  • [Presentation] Tranascriptional activation of c-fos gene by the NF complex2007

    • Author(s)
      Nakadai T, Shimada M, Fukuda A, Nogi Y, Hisatake K
    • Organizer
      Mechanisms of Eukaryotic Transcription, Cold Spring Harbor
    • Place of Presentation
      New York
    • Year and Date
      2007-08-31
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570164
  • [Presentation] Transcription : From Chromatin to mRNA, Transcription of c-fos gene via chromatin modification2006

    • Author(s)
      Shimada M, Nakadai T, Fukuda A, Nogi Y, Hisatake K
    • Organizer
      eystone Symposia, Regulation of Eukaryotic Taos
    • Place of Presentation
      New Mexico, USA
    • Year and Date
      2006-03-23
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18570164
  • 1.  HISATAKE Koji (70271236)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 2.  中太 智義 (10364770)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

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