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HASEGAWA Masanori  長谷川 政徳

ORCIDConnect your ORCID iD *help
Researcher Number 50383823
Other IDs
Affiliation (based on the past Project Information) *help 2023 – 2024: 東海大学, 医学部, 准教授
2018 – 2022: 東海大学, 医学部, 講師
2017: 慶應義塾大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 56030:Urology-related / Urology
Except Principal Investigator
Basic Section 56030:Urology-related
Keywords
Principal Investigator
フェロトーシス / 腎細胞癌 / 脂質 / 尿路上皮癌 / 前立腺癌 / アンドロゲン受容体 / 抗癌剤 / 抗癌剤耐性 / 泌尿器科学 / フェロプトーシス … More / 去勢抵抗性前立腺癌 / MUC1C蛋白 / ferroptosis / ドセタキセル / GPX4 / MUC1 / 去勢抵抗性 … More
Except Principal Investigator
診断 / OPLS-DA / 前立腺癌 / 糖ペプチド / CSGSA Less
  • Research Projects

    (5 results)
  • Research Products

    (6 results)
  • Co-Researchers

    (5 People)
  •  Investigation of the ferroptosis inhibition by sex hormones in urinary cancer and development of novel lipid-targeted therapyPrincipal Investigator

    • Principal Investigator
      長谷川 政徳
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Tokai University
  •  Comprehensive Serum Glycopeptide Spectra Analysis (CSGSA): A novel tool for detecting prostate cancer

    • Principal Investigator
      宮嶋 哲
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Keio University
  •  Establishment of a novel therapy for renal cell carcinoma by induction of ferroptosis via lipo-quality modulationPrincipal Investigator

    • Principal Investigator
      HASEGAWA Masanori
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Tokai University
  •  Establishment of a novel therapy for urothelial carcinoma by ferroptosisPrincipal Investigator

    • Principal Investigator
      HASEGAWA Masanori
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Tokai University
  •  Targeting MUC1 improve the docetaxel resistance and increase the sensitivity for ferroptosis in castration resistant prostate cancerPrincipal Investigator

    • Principal Investigator
      HASEGAWA Masanori
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Urology
    • Research Institution
      Tokai University
      Keio University

All 2023 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] IDH2 stabilizes HIF‐1α‐induced metabolic reprogramming and promotes chemoresistance in urothelial cancer2023

    • Author(s)
      Shigeta Keisuke、Hasegawa Masanori、Hishiki Takako、Naito Yoshiko、Baba Yuto、Mikami Shuji、Matsumoto Kazuhiro、Mizuno Ryuichi、Miyajima Akira、Kikuchi Eiji、Saya Hideyuki、Kosaka Takeo、Oya Mototsugu
    • Journal Title

      The EMBO Journal

      Volume: 42 Issue: 4 Pages: 1-27

    • DOI

      10.15252/embj.2022110620

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03817, KAKENHI-PROJECT-19K07468, KAKENHI-PROJECT-21K19579, KAKENHI-PROJECT-21K20811, KAKENHI-PROJECT-21K09381
  • [Journal Article] Role of the MUC1‐C oncoprotein in the acquisition of cisplatin resistance by urothelial carcinoma2020

    • Author(s)
      Shigeta Keisuke、Hasegawa Masanori、Kikuchi Eiji、Yasumizu Yota、Kosaka Takeo、Mizuno Ryuichi、Mikami Shuji、Miyajima Akira、Kufe Donald、Oya Mototsugu
    • Journal Title

      Cancer Science

      Volume: 111 Issue: 10 Pages: 3639-3652

    • DOI

      10.1111/cas.14574

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07468, KAKENHI-PROJECT-18H02939, KAKENHI-PROJECT-19K18599
  • [Presentation] de novo脂肪酸合成によるリポクオリティ調節は腎細胞癌におけるフェロトーシス感受性を変化させる2021

    • Author(s)
      長谷川政徳、山田鴻一郎、杠総一郎、金伯士、日暮太朗、 中野まゆら、川上正能、新田正広、河村好章、小路直、宮嶋哲
    • Organizer
      第109回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-21K09381
  • [Presentation] リポクオリティに着目したフェロトーシス誘導による泌尿器がんに対する新規治療法の確立2021

    • Author(s)
      長谷川政徳
    • Organizer
      第109回日本泌尿器科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-21K09381
  • [Presentation] 去勢抵抗性前立腺癌における膜結合型ムチンタンパク1(MUC1)を標的とした新規治療戦略2019

    • Author(s)
      長谷川政徳 茂田啓介 菊地栄次 大家基嗣 宮嶋哲
    • Organizer
      第28回泌尿器科分子・細胞研究会
    • Data Source
      KAKENHI-PROJECT-17K16814
  • [Presentation] 難治性前立腺癌におけるMUC1を中心とした分子ネットワーク制御による新規治療戦略2018

    • Author(s)
      長谷川政徳 小坂威雄 茂田啓介 宮嶋哲 大家基嗣
    • Organizer
      第34回前立腺シンポジウム
    • Data Source
      KAKENHI-PROJECT-17K16814
  • 1.  宮嶋 哲 (90245572)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  三上 修治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 3.  小坂 威雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  大家 基嗣
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  水野 隆一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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