Morimoto Tatuya 森本達也

… Alternative Names

Morimoto Tatsuya 森本達也

MORIMOTO Tatsuya 森本達也

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Researcher Number	50390779
Other IDs
External Links
Affiliation (Current)	2023: 静岡県立大学, 薬学部, 教授 2023: 独立行政法人国立病院機構(京都医療センター臨床研究センター), その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2023: 静岡県立大学, 薬学部, 教授 2014 – 2021: 静岡県立大学, 薬学部, 教授 2009 – 2011: University of Shizuoka, 薬学部, 教授 2008: Department of Clinical Research, National Hospital Organization Kyoto Medical Center, 展開医療研究部, 主任研究員 2007: Department of Clinical Research, National Hospital Organization Kyoto Medical Center, 展開医療研究部, 主任研究員 … More 2006: (財)生産開発科学研究所, 心血管分子細胞生物学・研究室, 主任研究員 2005 – 2006: Research Institute for Production Development, Laboratory of Cardiovascular Molecular Cellular Biology, Chief, 心血管分子細胞生物学研究室, 主任研究員 2004: 財団法人・生産開発科学研究所, 主任研究員 Less
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Biological pharmacy / Basic Section 47040:Pharmacology-related Except Principal Investigator Circulatory organs internal medicine / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Keywords	Principal Investigator 心筋細胞肥大 / p300 / GATA4 / プロテオミクス / 転写因子 / 心不全 / GATA-4 / ヒストンアセチルトランスフェラーゼ / Cdk9 / ｐ３００ … More / 治療薬 / トランスジェニックマウス / クロマチンリモデリング因子 / Ini1 / ＧＡＴＡ４ / 新規細胞肥大 / ES細胞 / 心筋分化 / embryonic stem (ES) cells / Proteomics / Cardiac myocytes differentiation / Transcription factor / エピジェネティック / ヒストン / ドラッグリポジショニング / ω３系脂肪酸 / ヒストンアセチル化酵素 / 結合タンパク / 心臓リモデリング / 心臓線維化 / ヒストンアセチル化 / 心肥大 / 多量体形成 … More Except Principal Investigator p300 / heart failure / cardiac myocyte / transcription / 心筋細胞 / 転写 / 心不全 / GATA-4 / hypertrophy / 性差 / 心臓 / 血管 / 性決定遺伝子 / iPS細胞 / 2卵性双生児 / 性染色体 / cardiac hypertrophy / fibrosis / p300 binding proteins Less

The studyon of p300 complex on cardiac hypertrophy and fibrosis during the development of heart failure
- Principal Investigator
  
  砂川陽一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  University of Shizuoka
ノックインマウスを用いた心不全によるGATA4多量体形成の変化並びに治療薬の探索研究Principal Investigator
- Principal Investigator
  
  森本達也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  University of Shizuoka
Identification and functional analysis of p300 regulatory factors involved in the development of heart failure using medical proteomicsPrincipal Investigator
- Principal Investigator
  
  森本達也
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  University of Shizuoka
Roles of sex chromosomes in pathophysiological sex difference formation in the heart
- Principal Investigator
  
  Kurokawa Junko
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  University of Shizuoka
Investigation of novel heart failure therapy targeting transcription complexPrincipal Investigator
- Principal Investigator
  
  Morimoto Tatsuya
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Identifying the novel therapeutic targets by investigating the regulatory mechanism of transcription complex during the development of heart failurePrincipal Investigator
- Principal Investigator
  
  Morimoto Tatsuya
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka
Analysis of activation mechanism of cardiac p300/GATA4 pathway during heart failurePrincipal Investigator
- Principal Investigator
  
  MORIMOTO Tatsuya
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  University of Shizuoka
Purification and analysis of a transoription factor, GATA4 complex from adult mouse heart during developing heart failurePrincipal Investigator
- Principal Investigator
  
  MORIMOTO Tatsuya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Department of Clinical Research, National Hospital Organization Kyoto Medical Center
Analysis of cardiac specific transcription factor GATA-4 complex during differentiation of mouse embryonic stem cells into cardiac myocytesPrincipal Investigator
- Principal Investigator
  
  MORIMOTO Tatsuya
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Research Institute for Production Development
Identification of intracellular signaling molecules that bind to cardiac p300 during the development of heart failure and its application to pharmacological therapy
- Principal Investigator
  
  HASEGAWA Koji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Clinical Research Institute, Kyoto Medical Center, National Hospital Organization

[Book] 転写因子のアセチル化と心臓リモデリング細胞工学Vol. 26 No 42007
- Author(s)
  森本達也, 長谷川浩二
- Total Pages
  5
- Publisher
  秀潤社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590770
[Journal Article] Cardiomyocyte Sirt (Sirtuin) 7 Ameliorates Stress-Induced Cardiac Hypertrophy by Interacting With and Deacetylating GATA42020
- Author(s)
  Yamamura Satoru、Izumiya Yasuhiro、Araki Satoshi、Nakamura Taishi、et al.
- Journal Title
  
  Hypertension
  
  Volume: 75 Issue: 1 Pages: 98-108
- DOI
  10.1161/hypertensionaha.119.13357
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08110, KAKENHI-PROJECT-19K22639, KAKENHI-PROJECT-19H03711, KAKENHI-PROJECT-17K08279, KAKENHI-PROJECT-16H06276
[Journal Article] The Synthetic Curcumin Analogue GO-Y030 Effectively Suppresses the Development of Pressure Overload-induced Heart Failure in Mice.2020
- Author(s)
  Shimizu K, Sunagawa Y, Funamoto M, Wakabayashi H, Genpei M, Miyazaki Y, Katanasaka Y, Sari N, Shimizu S, Katayama A, Shibata H, Iwabuchi Y, Kakeya H, Wada H, Hasegawa K, Morimoto T.
- Journal Title
  
  Sci Rep.
  
  Volume: 10(1) Issue: 1 Pages: 7172-7172
- DOI
  10.1038/s41598-020-64207-w
- NAID
  120006888478
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08279, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-18K08121
[Journal Article] Role of SIRT1 in Modulating Acetylation of the Sarco-Endoplasmic Reticulum Ca2+-ATPase in Heart Failure.2019
- Author(s)
  Gorski PA, Jang SP, Jeong D, Lee A, Lee P, Oh JG, Chepurko V, Yang DK, Kwak TH, Eom SH, Park ZY, Yoo YJ, Kim DH, Kook H, Sunagawa Y, Morimoto T, Hasegawa K, Sadoshima J, Hajjar RJ, Park WJ, Kho C.
- Journal Title
  
  Circ Res.
  
  Volume: 124(9) Issue: 9 Pages: 63-80
- DOI
  10.1161/circresaha.118.313865
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08279
[Journal Article] Regulation of Cardiac Transcription Factor GATA4 by Post-Translational Modification in Cardiomyocyte Hypertrophy and Heart Failure.2016
- Author(s)
  Katanasaka Y, Suzuki H, Sunagawa Y, Hasegawa K, Morimoto T.
- Journal Title
  
  International Heart Journal
  
  Volume: 6 Pages: 672-675
- NAID
  130005172007
- Data Source
  KAKENHI-PROJECT-26460071
[Journal Article] Functional Analysis of GATA4 Complex, a Cardiac Hypertrophy-response Transcriptional Factor, Using a Proteomics Approach.2016
- Author(s)
  1.Sunagawa Y, Katanasaka Y, Wada H, Hasegawa K, Morimoto T
- Journal Title
  
  Yakugaku Zasshi.
  
  Volume: 136 Pages: 151-6
- NAID
  130005121459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460071
[Journal Article] Tyrosine phosphorylation of RACK1 triggers cardiomyocyte hypertrophy by regulating the interaction between p300 and GATA4.2016
- Author(s)
  Suzuki H, Katanasaka Y, Sunagawa Y, Miyazaki Y, Funamoto M, Wada H, Hasegawa K, Morimoto T.
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 9 Issue: 9 Pages: 1544-1557
- DOI
  10.1016/j.bbadis.2016.05.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460071, KAKENHI-PROJECT-16K18876
[Journal Article] Functional Analysis of GATA4 Complex, a Cardiac Hypertrophy-response Transcriptional Factor, Using a Proteomics Approach2016
- Author(s)
  Sunagawa Y, Katanasaka Y, Wada H, Hasegawa K, Morimoto T.
- Journal Title
  
  YAKUGAKU ZASSHI
  
  Volume: 136 Issue: 2 Pages: 151-156
- DOI
  10.1248/yakushi.15-00226-2
- NAID
  130005121459
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2016-02-01
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860052, KAKENHI-PROJECT-26460071
[Journal Article] 心不全発症時における細胞内情報伝達機構2014
- Author(s)
  砂川陽一、刀坂泰史、森本達也、長谷川浩二
- Journal Title
  
  臨床心不全のいちばん大事なところ60
  
  Volume: 1 Pages: 14-18
- Data Source
  KAKENHI-PROJECT-26460071
[Journal Article] Optimal Dose-Setting Study of Curcumin for Improvement of Left Ventricular Systolic Function After Myocardial Infarction in Rats2014
- Author(s)
  Sunagawa y, Sono S, Katanasaka Y, Funamoto M, Hirano S, Miyazaki Y, Hojo Y,Suzuki H, Morimoto E, Marui A, Sataka R, Ueno M, Wada H, Hasegawa K, Morimoto t
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 126 Issue: 4 Pages: 329-336
- DOI
  10.1254/jphs.14151FP
- NAID
  130004704286
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460071
[Journal Article] α1-Antitrypsin Low-Density-Lipoprotein Serves as a Marker of Smoking-Specific Oxidative Stress2012
- Author(s)
  Hiromichi Wada
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 19 Issue: 1 Pages: 47-58
- DOI
  10.5551/jat.9035
- NAID
  130004721902
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590918, KAKENHI-PROJECT-21590944
[Journal Article] Innovative Preparation of Curcumin for Improved Oral Bioavailability2011
- Author(s)
  Sasaki H, Sunagawa Y, Takahashi K, Imaizumi A, Fukuda H, Hashimoto T, Wada H, atanasaka Y, Kakeya H, Fujita M, Hasegawa K, Morimoto T
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 34 Issue: 5 Pages: 660-665
- DOI
  10.1248/bpb.34.660
- NAID
  130000657776
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] Distinct characteristics of circulating vascular endothelial growth factor-A and C levels in human subjects2011
- Author(s)
  Wada H, Ura S, Kitaoka S, Satoh-Asahara N, Horie T, Ono K, Takaya T, Takanabe-Mori R, Akao M, Abe M, Morimoto T, Murayama T, Yokode M, Fujita M, Shimatsu A, Hasegawa K.
- Journal Title
  
  Pros ONE
  
  Volume: 6 Issue: 12 Pages: 29351-29351
- DOI
  10.1371/journal.pone.0029351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590592, KAKENHI-PROJECT-21590646, KAKENHI-PROJECT-21590918, KAKENHI-PROJECT-21590944, KAKENHI-PROJECT-22790703
[Journal Article] Cyclin-dependent kinase 9 forms a complex with GATA4 and is involved in the differentiation of mouse ES cells into cardiomyocytes2011
- Author(s)
  Kaichi S, Takaya T, Morimoto T, Sunagawa Y, Kawamura T, Ono K, Shimatsu A, Baba S, Heike T, Nakahata T, Hasegawa K
- Journal Title
  
  Journal of Cellular Physiology
  
  Volume: 226 Issue: 1 Pages: 248-254
- DOI
  10.1002/jcp.22336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] A Natural p300-Specific Histone Acetyltransferase Inhibitor, Curcumin, in Addition to Angiotensin-Converting Enzyme Inhibitor, Exerts Beneficial Effects on Left Ventricular Systolic Function After Myocardial Infarction in Rats2011
- Author(s)
  Yoichi sunagawa
- Journal Title
  
  Circ J
  
  Volume: 75 Issue: 9 Pages: 2151-2159
- DOI
  10.1253/circj.CJ-10-1072
- NAID
  10029339526
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J03435, KAKENHI-PROJECT-21590944
[Journal Article] Cyclin-dependent kinase 9 forms a complex with GATA4 and is involved in the differentiation of mouse ES cells into cardiomyocytes2011
- Author(s)
  Kaichi S, Takaya T, Morimoto T, Sunagawa Y, Kawamura T, Ono K, Shimatsu A, Baba S, Heike T, Nakahata T, Hasegawa K
- Journal Title
  
  J Cell Physiol
  
  Volume: 226(1) Pages: 248-54
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] Innovative preparation of curcumin for Improved oral bioavailability2011
- Author(s)
  Sasaki H, Sunagawa Y, Takahashi K, Imaizumi A, Fukuda H, Hashimoto T, Wada H, Katanasaka Y, Kakeya K, Fujita M, Hasegawa K, Morimoto T
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 34(5) Pages: 660-5
- NAID
  130000657776
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] A natural p300-specific histone acetyltransferase inhibitor, curcumin, in addition to angiotensin converting enzyme inhibitor exerts beneficial effects on left ventricular systolic function after myocardial infarction in rats2011
- Author(s)
  Sunagawa Y, Morimoto T, Wada H, Takaya T, Katanasaka Y, Kawamura T, Yanagi S, Marui A, Sakata R, Shimatsu A, Kimura T, Kakeya H, Fujita M, Hasegawa K
- Journal Title
  
  Circ J
  
  Volume: 75(9) Pages: 2151-9
- NAID
  10029339526
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] カレーに含まれるクルクミンの作用とその機序2010
- Author(s)
  森本達也
- Journal Title
  
  循環器科 Vol.67 No.2
  
  Pages: 208-215
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] クルクミンによる心機能改善効果の研究2010
- Author(s)
  森本達也
- Journal Title
  
  Anti-aging Science
  
  Volume: Vol.2, No.1 Pages: 67-71
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] Novel heart failure therapy targeting transcriptional pathway in cardiomyocytes by a natural compound, curcumin.2010
- Author(s)
  Tatsuya Morimoto
- Journal Title
  
  Circulation Journal
  
  Volume: 74 Pages: 1059-1066
- NAID
  10026474264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] Left Ventricular Expression of Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 in Failing Rat Hearts2010
- Author(s)
  Takaya T, Wada H, Morimoto T, Sunagawa Y, Kawamura T, Takanabe-Mori R, Shimatsu A, Fujita Y, Sato Y, Fujita M, Kimura T, Sawamura T, Hasegawa K
- Journal Title
  
  Circ J
  
  Volume: 74(4) Pages: 723-9
- NAID
  10026472482
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] Cyclin-dependent kinsase-9 is a component of p300/GATA4 complex required for phenylephrine-induced hypertrophy in cardiomyocytes2010
- Author(s)
  Sunagawa Y, Morimoto T, Takaya T, Wada H, Kawamura T, Fujita M, Shimatsu A, Kita T, Hasegawa K
- Journal Title
  
  J Biol Chem
  
  Volume: 285(13) Pages: 9556-68
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] カレーに含まれるクルクミンの作用とその機序2010
- Author(s)
  森本達也
- Journal Title
  
  循環器科
  
  Volume: Vol.67, No.2 Pages: 208-215
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] クルクミンによる心機能改善効果の研究2010
- Author(s)
  森本達也
- Journal Title
  
  Anti-aging Science Vol.2 No1
  
  Pages: 67-71
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] 天然成分クルクミンによる新規心不全治療2010
- Author(s)
  森本達也
- Journal Title
  
  BIO Clinica
  
  Volume: 25(3) Pages: 78-53
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] Hasegawa K Novel heart failure therapy targeting transcriptional pathway in cardiomyocytes by a natural compound, curcumin2010
- Author(s)
  Morimoto T, Sunagawa Y, Fujita M
- Journal Title
  
  Circ J
  
  Volume: 74(6) Pages: 1059-66
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] Aldosterone Signaling Associates with p300/GATA4 Transcriptional Pathway during Hypertrophic Responses in Cardiomyocytes2010
- Author(s)
  Yoshida Y, Morimoto T, Takaya T, Kawamura T, Sunagawa Y, Wada H, Fujita M, Shimatsu A, Kita T, Hasegawa K
- Journal Title
  
  Circ J
  
  Volume: 74(1) Pages: 156-62
- NAID
  10025941604
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] Excessive apoptosis as a downstream molecular event during the development of congenital heart diseases2010
- Author(s)
  Kaichi S, Hasegawa K, Morimoto T
- Journal Title
  
  Circ J
  
  Volume: 74(11) Pages: 2297-8
- NAID
  10026972554
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice2010
- Author(s)
  Kaichi S, Hasegawa K, Takaya T, Yokoo N, Mima T, Kawamura T, Morimoto T, Ono K, Baba S, Yamanaka S, Nakahata T, Heike T
- Journal Title
  
  Cardiovasc Res
  
  Volume: 88(2) Pages: 314-23
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] 心不全の分子標的療法の開発2009
- Author(s)
  森本達也
- Journal Title
  
  News letter(日本心不全学会) Vol.13 No2
  
  Pages: 10-11
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] 甲状腺機能異常症と循環器疾患―不整脈・心不全2009
- Author(s)
  森本達也
- Journal Title
  
  綜合臨床(特集甲状腺疾患をマスターすう) Vol.58 No7
  
  Pages: 1577-1582
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] カレーの成分の一つクルクミンの心臓に対する新しい作用2009
- Author(s)
  森本達也
- Journal Title
  
  Medical View Point Vol.30 No.4
  
  Pages: 2-2
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] MicroRNA-1 and MicroRNA-133 in spontaneous myocardial differentiation of mouse embryonic stem cells2009
- Author(s)
  Takaya T, Ono K, Kawamura T, Takanabe R, Kaichi S, Morimoto T, Wada H, Kita T, Shimatsu A, Hasegawa K
- Journal Title
  
  Circ J
  
  Volume: 73(8) Pages: 1397-8
- NAID
  10025933876
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] クルクミンによる新しい心不全治療2009
- Author(s)
  森本達也
- Journal Title
  
  医学のあゆみ 229 No8
  
  Pages: 646-647
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] 天然成分クルクミンによる新規心不全治療2009
- Author(s)
  森本達也
- Journal Title
  
  BIO Clinica 25(3)
  
  Pages: 81-87
- Data Source
  KAKENHI-PROJECT-21590944
[Journal Article] Statins activate GATA-6 and induce differentiatedvascular smooth muscle cells2008
- Author(s)
  Wada H, Abe M, Ono K, Morimoto T, Kawamura T, Takaya T, Satoh N, Fujita M, Kita T, Shimatsu A, Hasegawa K
- Journal Title
  
  Biochem Biophys Res Commun. 374(4)
  
  Pages: 731-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] Myocardial regulation of p300 and p53 by doxorubicin involves ubiquitin pathways2008
- Author(s)
  Morimoto T, Fujita M, Kawamura T, Sunagawa Y, Takaya T, Wada H, Shimatsu A, Kita T, Hasegawa K
- Journal Title
  
  Circ J 72
  
  Pages: 1506-11
- NAID
  110006894390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] Knowledge and interest regarding smoking-related health risks in smokers and non-smokers. Self-rating depression scale score is a strong independent predictor of smoking cessation outcomes2008
- Author(s)
  Wada H, Hasegawa K, Terashima S, Satoh N, Inoue M, lida Y, Yamakage H, Kitaoka S, Morimoto T. Fujita M, Shimatsu A, Takahashi Y
- Journal Title
  
  Smoking Control Science 4
  
  Pages: 4-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats2008
- Author(s)
  Morimoto T, Sunagawa Y, Kawamura T, Takaya T, Wada H, Nagasawa A, Komeda M, Fujita M, Shimatsu A, Kita T, Hasegawa K
- Journal Title
  
  J Clin Invest 118
  
  Pages: 868-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] 天然物クルクミンによる心筋細胞核をターゲットとした新しい心不全治療2008
- Author(s)
  森本達也、藤田正俊、長谷川浩
- Journal Title
  
  循環器専門医 16
  
  Pages: 253-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] Knowledge and interest regarding smoking-related health risks in smokers and nonsmokers. Self-rating depression scale score is a strong independent predictor of smoking cessation outcomes2008
- Author(s)
  Wada H, Hasegawa K, Terashima S, Satoh N, Inoue M, Iida Y, Yamakage H, Kitaoka S, Morimoto T, Fujita M, Shimatsu A, Takahashi Y.
- Journal Title
  
  Smoking Control Science 4
  
  Pages: 4-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats2008
- Author(s)
  Morimoto T. Sunagawa Y, Kawamura T, Takaya T, Wada H, Nagasawa A, Komeda M, Fujita M, Shimatsu A, Kita T, Hasegawa K
- Journal Title
  
  J Clin Invest. 18
  
  Pages: 868-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] Identification of p300-targeted acetylated residues in GATA-4 during hypertrophic responses in cardiac myocytes2008
- Author(s)
  Takaya T, Kawamura T, Morimoto T, Ono K, Kita T, Shimatsu A, Hasegawa K
- Journal Title
  
  J Biol Chem 283
  
  Pages: 9828-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] Myocardial Regulation of p300 and p53 by Doxorubicin Involves Ubiquitin Pathways2008
- Author(s)
  Morimoto T. Fujita M, Kawamura K, Sunagawa Y, Takaya T, Wada H, Shimatsu A, Kita T, Hasegawa K
- Journal Title
  
  Cire J. 72(9)
  
  Pages: 1506-11
- NAID
  110006894390
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] オルメサルタン服薬時刻の起床時血圧に及ぼす影響2008
- Author(s)
  藤田正俊, 猪飼亜希子, 森本達也, 中江出
- Journal Title
  
  Therapeutic Research Vol.29 No4
  
  Pages: 565-568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] The dietary compound curcumin inhibits p300 histone acetyltransferase activity and prevents heart failure in rats.2008
- Author(s)
  Tatsuya Morimoto
- Journal Title
  
  The Journal of Clinical Investigation 118
  
  Pages: 868-878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] Statins activate GATA-6 and induce differentiated vascular smooth muscle cells2008
- Author(s)
  Wada H, Abe M, Ono K, Morimoto T, Kawamura T, Takaya T, Satoh N, Fujita M, Kita T, Shimatsu A, Hasegawa K
- Journal Title
  
  Biochem Biophys Res Commun 374
  
  Pages: 731-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] Identification of p300-targeted acetylated residues in GATA-4 during hypertrophic responses in cardiac myocytes2008
- Author(s)
  Takaya T, Kawamura T, Morimoto T. Ono K, Kita T, Shimatsu A, Hasegawa K
- Journal Title
  
  J Bioi Chem. 283(15)
  
  Pages: 9828-35
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] 天然物クルクミンによる心筋細胞核をターゲットとした新しい心不全治療2008
- Author(s)
  森本達也, 藤田正俊, 長谷川浩二
- Journal Title
  
  循環器専門医 16巻2号
  
  Pages: 253-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] 心筋細胞核をターゲットとした新しい心不全治療の可能性2007
- Author(s)
  森本達也, 砂川陽一, 川村晃久, 高谷智英, 和田啓道, 宮本昌一, 長澤淳, 米田正始, 藤田正俊, 島津章, 北徹, 長谷川浩二
- Journal Title
  
  適応医学誌 Vol.1l.No.2
  
  Pages: 19-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] Trichostatin A induces myocardial differentiation of monkey ES cells2007
- Author(s)
  Hosseinkhani M, Hasegawa K, Ono K, Kawamura T, Takaya T, Morimoto T, Wada H, Shimatsu A, Prat SG, Suemori H, Nakatsuji N, Kita T.
- Journal Title
  
  Biochem Biophys Res Commun. 356(2)
  
  Pages: 386-91
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590770
[Journal Article] Dose-dependency in pleiotropic effects of atorvastatin2007
- Author(s)
  Fujita M, Morimoto T, Ikemoto M, Takeda M, Ikai A, Miwa K
- Journal Title
  
  Int J Angiol. 16(3)
  
  Pages: 89-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] 転写因子のアセチル化と心臓リモデリング2007
- Author(s)
  森本達也
- Journal Title
  
  細胞工学 Vol.26 No4
  
  Pages: 396-400
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] Trichostatin A induces myocardial differentiation of monkey ES cells2007
- Author(s)
  Hosseinkhani M, Hasegawa K, Ono K, Kawamura T, Takaya T. Morimoto T. Wada H, Shimatsu A, Prat SG, Suemori H, Nakatsuji N, Kita T
- Journal Title
  
  Biochem Biophys Res Commun. 356(2)
  
  Pages: 386-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] 転写因子のアセチル化と心臓リモデリング2007
- Author(s)
  森本達也, 長谷川浩二
- Journal Title
  
  細胞工学 Vol.26 No4
  
  Pages: 396-400
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] 心筋細胞核をターゲットとした新しい心不全治療の可能性2007
- Author(s)
  森本達也
- Journal Title
  
  適応医学誌 Vol.11. No.2
  
  Pages: 19-26
- Data Source
  KAKENHI-PROJECT-19590842
[Journal Article] Histone acetyltransferase activity of p300 is required for the promotion of left ventricular remodeling following myocardial infarction in adult mice in vivo2006
- Author(s)
  Miyamoto S, Kawamura T, Morimoto T, Ono K, Kawase Y, Kita T, Hasegawa K
- Journal Title
  
  Circulation. 113(5)
  
  Pages: 679-90
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590770
[Journal Article] Histone acetyltranferase activity of p300 is required for the promotion of left ventricular remodeling following myocardial infarction in adult mice in vivo.2006
- Author(s)
  Miyamoto S, Kawamura T, Morimoto T, Ono K, Wada H, Kawase Y, Matsumori A, Nishio R, Kita T, Hasegawa K.
- Journal Title
  
  Circulation 113
  
  Pages: 679-690
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390230
[Journal Article] Histone acetyltransferase activity of p300 is required for the promotion of left ventricular remodeling following myocardial infarction in adult mice in vivo2006
- Author(s)
  Miyamoto S, Kawamura T, Morimoto T et al.
- Journal Title
  
  Circulation 113(5)
  
  Pages: 679-690
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590770
[Journal Article] Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes.2005
- Author(s)
  Kawamura T, Ono K, Morimoto T, Wada H, Hirai M, Hidaka K, Morisaki T, Heike T, Nakahata T, Kita T, Hasegawa K.
- Journal Title
  
  J Biol Chem 280
  
  Pages: 19682-19688
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390230
[Journal Article] Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes.2005
- Author(s)
  Kawamura T, Ono K, Morimoto T, Wada H, Hirai M, Hidaka K, Morisaki T, Heike T, Nakahata T, Kita T, Hasegawa K.
- Journal Title
  
  J Biol Chem. 280(20)
  
  Pages: 19682-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590770
[Journal Article] Acetylation of GATA-4 is involved in the differentiation of embryonic stem cells into cardiac myocytes.2005
- Author(s)
  Kawamura T, Ono K, Morimoto T et al.
- Journal Title
  
  Journal of Biological Chemistry 280(20)
  
  Pages: 19682-19688
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590770
[Journal Article] Endothelin-1-dependent nuclear factor of activated T lymphocyte signaling associates with transcriptional coactivator p300 in the activation of the B cell leukemia-2 promoter in cardiac myocytes.2004
- Author(s)
  Kawamura T, Ono K, Morimoto T, Akao M, Iwai-Kanai E, Wada H, Sowa N, Kita T, Hasegawa K.
- Journal Title
  
  Circ Res. 94
  
  Pages: 1492-1499
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390230
[Journal Article] FOG-2 competes with GATA-4 for a transcriptional coactivator p300 and represses hypertrophic responses in cardiac myocytes.2004
- Author(s)
  Hirai M, Ono K, Morimoto T, Kawamura T, Wada H, Kita T, Hasegawa K.
- Journal Title
  
  J Biol Chem 279
  
  Pages: 37640-37650
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390230
[Journal Article] FOG-2 competes with GATA-4 for a transcriptional coactivator p300 and represses hypertrophic responses in cardiac myocytes.2004
- Author(s)
  Hirai M, Ono K, Morimoto T, et al.
- Journal Title
  
  Journal of Biological Chemistry 279
  
  Pages: 37640-37650
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390230
[Journal Article] Endothelin-l-dependent nuclear factor of activated T lymphocyte signaling associates with transcriptional coactivator p300 in the activation of the B cell leukemia-2 promoter in cardiac myocytes.2004
- Author(s)
  Kawamura T, Ono K, Morimoto T et al.
- Journal Title
  
  Circulation Research 94
  
  Pages: 1492-1499
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390230
[Patent] 心血管予防治療剤2014
- Inventor(s)
  森本達也、長谷川浩二、村上明、福田宏之、高橋健治
- Industrial Property Rights Holder
  静岡県公立大学法人、長谷川浩二、他
- Industrial Property Rights Type
  特許
- Filing Date
  2014-04-18
- Acquisition Date
  2014-08-15
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] p300結合タンパク質であるSTK39のノックダウンは心筋細胞の肥大を誘発する2020
- Author(s)
  海野瑞紀、松下優作、砂川陽一、船本雅文、清水果奈、Nurmila Sari、清水聡史、宮﨑雄輔、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2020
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] A novel p300 binding protein regulates cardiomyocyte hypertrophy2020
- Author(s)
  Yusaku Matsushita, Yoichi Sunagawa, Mizuki Unno, Masafumi Funamoto, Kana Smizu, Satoshi Shimizu, Nurmila Sari, Yasufumi Kataka, Yusuke Miyazaki, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第25回静岡健康・長寿学術フォーラム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] BPK1, a novel p300-binding protein, regulated p300-mediated hypertrophic response in cultured cardiomyocytes2020
- Author(s)
  Mizuki Unno, Yusaku Matsushita, Yoichi Sunagawa , Masafumi Funamoto , Kana Shimizu , Satoshi Shimizu , Nurmila Sari , Yasufumi Katanasaka , Yusuke Miyazaki , Hiromichi Wada , Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第25回静岡健康・長寿学術フォーラム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] p300結合因子のSTK39はノックダウンにより培養心筋細胞の肥大反応を誘発した2020
- Author(s)
  海野瑞紀、松下優作、砂川陽一、船本雅文、清水果奈、Nurmila Sari、清水聡史、宮﨑雄輔、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  第143回　日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] 遺伝子改変マウスを用いた心臓特異的なp300結合タンパク質の同定及び機能解析2020
- Author(s)
  松下優作、砂川陽一、海野瑞紀、船本雅文、清水果奈、清水聡史、サリヌーミラ、刀坂泰史、宮崎雄輔、和田啓道、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2020
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] Analysis of a novel p300 binding protein in the regulation of cardiomyocyte hypertrophy2020
- Author(s)
  Yusaku Matsushita, Yoichi Sunagawa, Mizuki Unno, Masafumi Funamoto, Kana Smizu, Satoshi Shimizu, Nurmila Sari, Yasufumi Kataka, Yusuke Miyazaki, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第4回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] 5-HT2A受容体拮抗薬サルポグレラートは心筋細胞肥大を抑制した2020
- Author(s)
  川上由揮、清水果奈、砂川陽一、船本雅文、刀坂泰史、宮崎雄輔、本多大樹、サリヌーミラ、清水聡史、和田啓道、長谷川浩二、森本達也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 新規p300結合タンパク質であるBP1は心筋細胞肥大を促進した2020
- Author(s)
  松下優作、砂川陽一、海野瑞紀、船本雅文、清水果奈、清水聡史、サリヌーミラ、刀坂泰史、宮崎雄輔、和田啓道、長谷川浩二、森本達也
- Organizer
  第143回　日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] 5-HT2A受容体アンタゴニストであるサルポグレラートの心不全抑制効果についての検討2020
- Author(s)
  清水果奈、砂川陽一、船本雅文、刀坂泰史、宮崎雄輔、本多大樹、川上由輝、サリヌーミラ、清水聡史、和田啓道、長谷川浩二、森本達也
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 新規p300結合タンパク質であるp300-binding protein 1は培養心筋細胞において肥大反応を促進した2020
- Author(s)
  海野瑞紀、砂川陽一、松下優作、船本雅文、清水果奈、清水聡史、刀坂泰史、宮崎雄輔、長谷川浩二、森本達也
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] Identification of Novel p300 Binding Proteins, which Are Involved in Cardiomyocyte Hypertrophy2020
- Author(s)
  Yoichi Sunagawa, Yusaku, Matsushita, Mizuki Unno, Sho Uehara, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Sari Nurmila, Yusuke Miyazaki, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第85回日本循環器学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] 心不全発症に関与する新規p300結合タンパク質の同定及び機能解析2020
- Author(s)
  松下優作、砂川陽一、海野瑞紀、船本雅文、清水果奈、清水聡史、サリヌーミラ、刀坂泰史、宮崎雄輔、和田啓道、長谷川浩二、森本達也
- Organizer
  第20回抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] 心筋細胞肥大抑制作用を有する天然化合物の探索2019
- Author(s)
  前川健也、砂川陽一、船本雅文、清水果奈、刀坂泰史、宮崎雄輔、清水聡史、Nurmila Sari、和田啓道、長谷川浩二、森本達也
- Organizer
  第21回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] Metforminはp300-HAT活性を直接阻害することで心筋細胞の肥大を抑制する2019
- Author(s)
  清水圭貴、片山歩実、砂川陽一、船本雅文、清水果奈、Nurmila Sari、清水聡史、宮崎雄輔、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  第65回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 糖尿病治療薬 Metformin はp300-HAT活性を阻害することにより心筋細胞の肥大反応を抑制した2019
- Author(s)
  清水圭貴、片山歩実、砂川陽一、船本雅文、清水果奈、清水聡史、Nurmila Sari、宮崎雄輔、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  第21回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] Zerumbone Inhibits Cardiac Remodering and Dysfunction in Pressure Overload-induced Heart Failure Model Mice2019
- Author(s)
  Yuga Sugiyama, Nurmila Sari, Yasufumi Katanasaka, Yoichi Sunagawa, Yusuke Miyazaki, Masafumi Funamoto, Satoshi Shimizu, Kana Shimizu, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第24回静岡健康・長寿フォーラム
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] An Anti-Hypertrophic Effect On An Active Edible Ginger Components, Zerumbone In Heart Failure Model Mice2019
- Author(s)
  Nurmila Sari, Yasufumi Katanasaka, Hikaru Sato, Yuga Sugiyama, Yusuke Miyazaki, Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  Bandung International Conference on Food and Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] Metformin suppresses cardiomyocyte hypertrophy and p300 histone acetyltransferase activity2019
- Author(s)
  Kiyotaka Shimizu, Ayumi Katayama, Yoichi Sunagawa, Masafumi Funamoto, Yusuke Miyazaki, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第24回静岡健康・長寿フォーラム
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] Metforminは直接p300を阻害することで、心筋細胞肥大反応を抑制した2019
- Author(s)
  清水圭貴、片山歩実、砂川陽一、船本雅文、Nurmila Sari、清水果奈、清水聡史、宮崎雄輔、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  第23回日本心不全学会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 抗心筋細胞肥大作用を有する天然物化合物の探索2019
- Author(s)
  前川健也、砂川陽一、船本雅文、清水果奈、刀坂泰史、宮崎雄輔、清水聡史、Nurmila Sari、和田啓道、長谷川浩二、森本達也
- Organizer
  第4回J-ISCP年次学術集会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] ω -3 系多価不飽和脂肪酸である EPA および DHA は心筋細胞肥大および心筋梗塞後心不全の進展を同程度に抑制した2019
- Author(s)
  片山歩実、砂川陽一、船本雅文、清水果奈、源平麻衣、宮崎雄輔、刀坂泰史、Nurmila Sari、清水聡史、和田啓道、長谷川浩二、森本達也
- Organizer
  第19回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 心肥大に重要であるp300のヒストンアセチル化酵素活性を指標としたクルクミンの構造活性相関の検討2019
- Author(s)
  清水果奈、船本雅文、砂川陽一、刀坂泰史、宮崎雄輔、Nurmira Sari、清水聡史、柴田浩行、和田啓道、長谷川浩二、森本達也
- Organizer
  第19回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] EPAとDHAの心不全に対する効果の比較検討2019
- Author(s)
  片山歩実、砂川陽一、船本雅文、清水果奈、清水圭貴、前川健也、宮崎雄輔、刀坂泰史、Nurmila Sari、清水聡史、和田啓道、長谷川浩二、森本達也
- Organizer
  第21回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] ハナショウガ成分Zerumboneによる心筋細胞肥大及び心臓線維化抑制効果の検討2019
- Author(s)
  杉山優雅、Nurmila Sari、刀坂泰史、砂川陽一、宮崎雄輔、船本雅文、清水聡史、清水果奈、和田啓道、長谷川浩二、森本達也
- Organizer
  第4回J-ISCP年次学術集会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 天然物クルクミンを用いた新規心不全治療の可能性2019
- Author(s)
  森本達也、砂川陽一、宮崎雄輔、刀坂泰史、長谷川浩二
- Organizer
  第4回J-ISCP年次学術集会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] ハナショウガ成分Zerumboneによる心不全抑制効果の検討2019
- Author(s)
  "杉山優雅、刀坂泰史、Nurmila Sari、船本雅文、清水果奈、清水聡史、宮崎雄輔、砂川陽一、和田啓道、長谷川浩二、森本達也 "
- Organizer
  第65回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] EPA、DHAは同レベルに心筋梗塞モデルラットの心不全を抑制した2019
- Author(s)
  片山歩実、砂川陽一、船本雅文、清水果奈、源平麻衣、清水圭貴、前川健也、Nurmila Sari、清水聡史、宮崎雄輔、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  第4回J-ISCP年次学術集会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] クルクミン類似体GO-Y030のp300-ヒストンアセチル化酵素活性阻害作用の増強には芳香環3,5位のアルコキシ基が重要であった2019
- Author(s)
  清水果奈、船本雅文、砂川陽一、刀坂泰史、宮崎雄輔、Nurmila Sari、清水聡史、柴田浩行、和田啓道、長谷川浩二、森本達也
- Organizer
  第73回日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] The 5-HT2A Receptor Antagonist Sarpogrelate Suppresses Pressure Overload-Induced Development of Heart Failure in Mice2019
- Author(s)
  Kana Shimizu, Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Yusuke Miyazaki, Noriyuki Murai, Hiroki Honda, Satoshi Shimizu, Nurmila Sari, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  AHA 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] EPAとDHAは心筋細胞肥大反応および心筋梗塞モデルラットの心不全進展を抑制した2019
- Author(s)
  片山歩実、砂川陽一、船本雅文、清水果奈、源平麻衣、清水圭貴、前川健也、宮崎雄輔、刀坂泰史、Nurmila Sari、清水聡史、和田啓道、長谷川浩二、森本達也
- Organizer
  第65回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] EPAとDHAはp300-HAT活性を直接阻害し、同レベルに心筋梗塞モデルラットの心不全進展を抑制した2019
- Author(s)
  片山歩実、砂川陽一、船本雅文、清水果奈、源平麻衣、清水圭貴、前川健也、宮崎雄輔、刀坂泰史、Nurmila Sari、清水聡史、和田啓道、長谷川浩二、森本達也
- Organizer
  第23回日本心不全学会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] The effect of natural extracts on cardiomyocyte hypertrophy2019
- Author(s)
  Tatsuya Makawa, yoichi Sunagawa, Masafumi Funamoto, Yasufumi Katanasaka, Yusuke Miyazaki, Kana Shimizu, Nurmila Sari, Satoshi Shimizu, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第24回静岡健康・長寿フォーラム
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 心不全治療薬探索を目的とした心筋細胞面積測定ハイスループットスクリーニング系の確立2019
- Author(s)
  茂木光、清水聡史、砂川陽一、船本雅文、Nurmila Sari、清水果奈、宮崎雄輔、刀坂泰史、小郷尚久、浅井章良、和田啓道、長谷川浩二、森本達也
- Organizer
  第19回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 天然物抽出ライブラリーを用いた抗心筋細胞肥大作用を有する化合物の探索2019
- Author(s)
  前川健也、砂川陽一、船本雅文、清水果奈、刀坂泰史、宮崎雄輔、清水聡史、Nurmila Sari、和田啓道、長谷川浩二、森本達也
- Organizer
  第65回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 構造活性相関により同定したクルクミン類似体GO-Y030は心不全の進行を効果的に抑制した2019
- Author(s)
  清水果奈、船本雅文、砂川陽一、刀坂泰史、宮崎雄輔、Nurmila Sari、清水聡史、柴田浩行、和田啓道、長谷川浩二、森本達也
- Organizer
  第65回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] クルクミン類似体GO-Y030は強力にp300のヒストンアセチル化酵素活性、心筋細胞肥大及び心不全の進行を抑制した2019
- Author(s)
  清水果奈、船本雅文、砂川陽一、刀坂泰史、宮崎雄輔、Nurmira Sari、清水聡史、柴田浩行、和田啓道、長谷川浩二、森本達也
- Organizer
  第4回J-ISCP年次学術集会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 柑橘類由来の天然物Nobiletinは心筋細胞肥大抑制作用を持つ2019
- Author(s)
  江部綾華、砂川陽一、刀坂泰史、宮崎雄輔、船本雅文、清水果奈、Nurmila Sari、清水聡史、村上明、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第73回日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 糖尿病治療薬メトホルミンはp300-HAT活性阻害により心筋細胞肥大を抑制した2019
- Author(s)
  清水圭貴、片山歩実、砂川陽一、船本雅文、清水果奈、清水聡史、Nurmila Sari、宮崎雄輔、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  第4回J-ISCP年次学術集会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] Natural products derived from Jamu, prevent the development f cardiomyocyte hypertrophy and fibrosis phenotype in primary cultured cells2019
- Author(s)
  Nurmila Sari, Yasufumi Katanasaka, Yuga Sugiyama, Yusuke Miyazaki, Yoichi Sunagawa, Masafumi Funamoto, Satoshi Shimizu, Kana Shimizu, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第4回J-ISCP年次学術集会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] Omega-3 fatty acids, EPA and DHA, Repress p300-HAT-induced Hypertrophic Responses and Prevent MI-induced Development of Heart Failure2019
- Author(s)
  Ayumi Katayama, Yoichi Sunagawa, Masafumi Funamoto, Kana Shimizu, Mai Genpei, Yusuke Miyazaki, Yasufumi Katanasaka, Nurmila Sari, Satshi Shimizu, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第24回静岡健康・長寿フォーラム
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] Effects of Jamu component on cardiomyocyte hypertrophy and fibrotic pheotype in primary cultured cells2019
- Author(s)
  Nurmila Sari, Yasufumi Katanasaka, Yuga Sugiyama, Yusuke Miyazaki, Yoichi Sunagawa, Masafumi Funamoto, Satoshi Shimizu, Kana Shimizu, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第24回静岡健康・長寿フォーラム
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 心不全予防食品であるクルクミンの基礎及び臨床研究2019
- Author(s)
  森本達也
- Organizer
  第73回日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 心筋細胞肥大抑制効果を持つ機能性成分の探索2019
- Author(s)
  前川健也、砂川陽一、船本雅文、清水果奈、刀坂泰史、宮崎雄輔、清水聡史、Nurmila Sari、和田啓道、長谷川浩二、森本達也
- Organizer
  第73回日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 初代培養心筋細胞肥大を指標とした心不全治療薬候補探索ハイスループットスクリーニングの確立2019
- Author(s)
  茂木光、清水聡史、砂川陽一、船本雅文、Nurmila Sari、清水果奈、宮崎雄輔、刀坂泰史、小郷尚久、浅井章良、和田啓道、長谷川浩二、森本達也
- Organizer
  第73回日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] ハナショウガ成分Zerumboneによる心筋細胞肥大および心臓線維化抑制効果の検討2019
- Author(s)
  "杉山優雅、刀坂泰史、村田謄行、Nurmila Sari、船本雅文、清水果奈、清水聡史、宮崎雄輔、砂川陽一、和田啓道、長谷川浩二、森本達也 "
- Organizer
  第73回日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] ハナショウガ成分Zerumboneによる心不全抑制効果の検討2019
- Author(s)
  杉山優雅、刀坂泰史、Nurmila Sari、船本雅文、清水果奈、清水聡史、宮崎雄輔、砂川陽一、和田啓道、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2019
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] カカオポリフェノールの圧負荷心不全モデルマウスに対する改善効果の検討2019
- Author(s)
  曾布川実里、刀坂泰史、本多大樹、宮崎雄輔、船本雅文、Nurmila Sari、清水果奈、清水聡史、砂川陽一、和田啓道、長谷川浩二、森本達也
- Organizer
  第73回日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] EPAおよびDHAは同程度にp300のHAT活性を直接阻害し、心筋梗塞後心不全の進展を抑制した2019
- Author(s)
  片山歩実、砂川陽一、船本雅文、清水果奈、源平麻衣、宮崎雄輔、刀坂泰史、Nurmila Sari、清水聡史、和田啓道、長谷川浩二、森本達也
- Organizer
  第73回日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] A Jamu component, α-mangostine, prevented cardiomyocyte hypertrophy and fibrosis responses2019
- Author(s)
  Nurmila Sari、刀坂泰史、本多大樹、船本雅文、清水果奈、清水聡史、宮崎雄輔、砂川陽一、和田啓道、長谷川浩二、森本達也
- Organizer
  第65回日本薬学会東海支部総会・大会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 圧負荷応答性心不全に対するZerumboneの薬理作用の検討2019
- Author(s)
  杉山優雅、刀坂泰史、Nurmila Sari、船本雅文、清水果奈、清水聡史、宮崎雄輔、砂川陽一、和田啓道、長谷川浩二、森本達也
- Organizer
  第21回応用薬理シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 糖尿病治療薬メトホルミンは肥大した心筋細胞に対してp300-HAT活性を抑制することで肥大を抑制した2019
- Author(s)
  清水圭貴、片山歩実、、砂川陽一、源平麻衣、船本雅文、清水果奈、清水聡史、Nurmila Sari、宮崎雄輔、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  第73回日本栄養・食糧学会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 糖尿病治療薬 Metformin は心筋細胞肥大に関わる p300-HAT 活性を直接抑制した2019
- Author(s)
  清水圭貴、片山歩実、砂川陽一、源平麻衣、船本雅文、清水果奈、清水聡史、Nurmila Sari、宮崎雄輔、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  第19回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] カカオポリフェノールによる心不全改善効果2018
- Author(s)
  森本達也
- Organizer
  第23回チョコレート・ココア国際栄養シンポジウム
- Data Source
  KAKENHI-PROJECT-17K08279
[Presentation] 心筋特異的転写因子GATA4の二量体形成にはC末のZFドメインが重要である2017
- Author(s)
  清水聡史、依光奈津美、砂川陽一、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  宮城
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心不全に関わる転写因子GATA4 C-terminal Zinc Fingerの結晶構造解析2017
- Author(s)
  清水聡史、原幸大、依光奈津美、砂川陽一、刀坂泰史、和田啓道、長谷川浩二、橋本博、森本達也
- Organizer
  2016年度量子ビームサイエンスフェスタ
- Place of Presentation
  茨木
- Year and Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] The dimerization domain of GATA4 is involved in the activation of hypertrophic responses2017
- Author(s)
  Satoshi Shimizu, Natsumi Yorimitsu, Yoichi Sunagawa, Masafumi Funamoto, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  石川
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] p300/GATA4 依存的心肥大反応における WDR5/MLL1 メチル化酵素複合体の機能解析2017
- Author(s)
  村田謄行、天野七菜、刀坂泰史、永井陽介、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  宮城
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 生体内における新規GATA4 結合因子であるRACK1 のチロシンリン酸化を介した心肥大反応制御機構の解明2017
- Author(s)
  船本雅文、鈴木秀敏、刀坂泰史、砂川陽一、宮崎雄輔、和田啓道、長谷川浩二、森本達也
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  宮城
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] RACK1のチロシン脱リン酸化は心筋細胞肥大反応を抑制した2017
- Author(s)
  宮崎雄輔、鈴木秀敏、刀坂泰史、砂川陽一、船本雅文、和田啓道、長谷川浩二、森本達也
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  宮城
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心筋特異的転写因子 GATA4 の二量体形成には C 末の ZF ドメインが重要である2017
- Author(s)
  清水聡史, 依光奈津美, 砂川陽一, 刀坂泰史, 和田啓道, 長谷川浩二, 森本達也
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  宮城
- Year and Date
  2017-03-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Homo-dimarization domain of GATA4 involved in p300/GATA4-dependent hypertrophic gene activations2016
- Author(s)
  Natsumi Yorimitsu, Yoichi Sunagawa,Satoshi Shimizu, Yasufumi Katanasaka,Hiromichi Wada, Koji Hasegawa,Tatsuya Morimoto
- Organizer
  第11回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] アルギニンメチル化酵素PRMT5は加齢に伴う心肥大を促進する2016
- Author(s)
  刀坂泰史、若林弘樹、櫻井涼賀、宮崎雄輔、砂川陽一、和田啓道、長谷川浩二、森本達也
- Organizer
  第16回日本抗加齢医学会総会
- Place of Presentation
  神奈川
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] PRMT5 methylates p300 and induce cardiac hyper2016
- Author(s)
  Yusuke Miyazaki, Yasufumi Katanasaka, Yoichi Sunagawa, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto
- Organizer
  ISCP2016
- Place of Presentation
  中国
- Year and Date
  2016-10-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] PRMT5はp300をメチル化し心肥大を誘発する2016
- Author(s)
  宮﨑雄輔、刀坂泰史、北條祐也、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第2回J-ISCP学術集会
- Place of Presentation
  徳島
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心肥大応答を司る転写因子GATA4のホモ二量体化形成はZincフィンガードメインを介して行われる2016
- Author(s)
  清水聡史、依光奈津美、砂川陽一、刀坂泰史、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本薬学会第136年回
- Place of Presentation
  神奈川
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Acetylation of GATA4 is required for the formation of GATA4 Homo-dimerization.2016
- Author(s)
  Satoshi Shimizu, Natsumi Yorimitsu, Yoichi Sunagawa, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 3rd International Conference on Pharma-Food
- Place of Presentation
  静岡
- Year and Date
  2016-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Overexpression of GATA4 dimerization domain inhibited p300/GATA4-dependent hypertrophic genes transcription.2016
- Author(s)
  Natsumi Yorimitsu, Yoichi Sunagawa, Satoshi Shimizu, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 3rd International Conference on Pharma-Food
- Place of Presentation
  静岡
- Year and Date
  2016-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] ARBはRACK1のリン酸化を抑制して心肥大を制御する2016
- Author(s)
  船本雅文、刀坂泰史、砂川陽一、宮崎雄輔、和田啓道、長谷川浩二、森本達也
- Organizer
  日本薬学会東海支部大会合同学術大会2016
- Place of Presentation
  岐阜
- Year and Date
  2016-10-30
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心筋細胞肥大時におけるGATA4のアセチル化とリン酸化のクロストークについて2016
- Author(s)
  砂川陽一、船本雅文、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  第６２回日本薬学会東海支部総会・大会
- Place of Presentation
  愛知
- Year and Date
  2016-07-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] PRMT5/MEP50 complex regulates p300/GATA4-induced cardiac hypertrophy2016
- Author(s)
  Yusuke Miyazaki, Yasufumi Katanasaka, Yoichi Sunagawa, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto
- Organizer
  第80回日本循環器学会学術集会
- Place of Presentation
  宮城
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] WDR5によるｐ300/ＧＡＴＡ4誘導性心肥大反応の抑制機構の検討2016
- Author(s)
  天野七菜、刀坂泰史、永井陽介、砂川陽一、和田弘道、長谷川浩二、森本達也
- Organizer
  日本薬学会東海支部大会合同学術大会2016
- Place of Presentation
  岐阜
- Year and Date
  2016-10-30
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心肥大反応を司る転写因子GATA4の二量体はC末のZFドメインで形成される2016
- Author(s)
  依光奈津美、清水聡史、砂川陽一、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  日本薬学会東海支部大会合同学術大会2016
- Place of Presentation
  岐阜
- Year and Date
  2016-10-30
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 新規ＧＡＴＡ4結合タンパク質ＷＤＲ5は心筋細胞肥大を抑制する2016
- Author(s)
  天野七菜、刀坂泰史、永井陽介、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本薬学会第136年回
- Place of Presentation
  神奈川
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] アルギニンメチル化酵素PRMT5は老化における心機能低下を促進する2016
- Author(s)
  若林弘樹、刀坂泰史、櫻井涼賀、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第2回J-ISCP学術集会
- Place of Presentation
  徳島
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心肥大期から心不全期にかけてp300によるヒストンアセチル化修飾部位は変化する2016
- Author(s)
  船本雅文、砂川陽一、清水果奈、刀坂泰史、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本薬学会第136年回
- Place of Presentation
  神奈川
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] PRMT5心臓特異的過剰発現マウスにおける左心室収縮能への影響2016
- Author(s)
  若林弘樹、刀坂泰史、櫻井涼賀、砂川陽一、和田啓道、長谷川浩二、森本達也
- Organizer
  第26回日本循環薬理学会
- Place of Presentation
  長野
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Acetylated form of GATA4 is required for GATA4 homo-dimerization2016
- Author(s)
  Satoshi Shimizu, Natsumi Yorimitsu, Yoichi Sunagawa, Masafumi Funamoto, Yasufumi Katanasaka, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第11回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Homo-dimarization domain of GATA4 is Formed through C-terminal Zinc Fingur Domain2016
- Author(s)
  Satoshi Shimizu, Natsumi Yorimitsu, Yoichi Sunagawa, Yasufumi Katanasaka, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  International Society of Cardiomyopathies and Heart Failure Congress 2016
- Place of Presentation
  京都
- Year and Date
  2016-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心臓特異的ＰＲＭＴ5過剰発現マウスは加齢に伴い心機能が低下した2016
- Author(s)
  若林弘樹、刀坂泰史、櫻井涼賀、砂川陽一、和田弘道、長谷川浩二、森本達也
- Organizer
  日本薬学会東海支部大会合同学術大会2016
- Place of Presentation
  岐阜
- Year and Date
  2016-10-30
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] WD repeat-containing protein 5 inhibits p300/GATA4-induced hypertrophic response2016
- Author(s)
  Nana Amano, Yasufumi Katanasaka, Yoichi sunagawa, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 3rd International Conference on Pharma-Food
- Place of Presentation
  静岡
- Year and Date
  2016-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Epigenetic Modifications via Histone Acetylation by p300 are Changed during the Transition from Cardiac Hypertrophy to Heart Failure2016
- Author(s)
  Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第80回日本循環器学会学術集会
- Place of Presentation
  宮城
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] トランスジェニックマウスを用いた圧負荷心不全におけるPRMT5の機能解析2016
- Author(s)
  筒井優介、櫻井涼賀、刀坂泰史、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第2回J-ISCP学術集会
- Place of Presentation
  徳島
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] PRMT5/MEP50 Regulates Cardiomyocyte Hypertrophy by　Inhibiting p300-Induced Acetylation of GATA42016
- Author(s)
  Yusuke Tsutsui, Yusuke Miyazaki,　Yasufumi Katanasaka, Yoichi Sunagawa, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  European Society of Cardiology Congress 2016
- Place of Presentation
  Roma
- Year and Date
  2016-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] アルギニンメチル化酵素PRMT5はp300をメチル化する2016
- Author(s)
  本多大樹、刀坂泰史、北條祐也、宮崎雄輔、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第2回J-ISCP学術集会
- Place of Presentation
  徳島
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心筋細胞肥大に関与する転写因子GATA4はZincフィンガードメインで直接結合し、ホモ二量体を形成する2016
- Author(s)
  清水聡史、依光奈津美、砂川陽一、刀坂泰史、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第2回J-ISCP学術集会
- Place of Presentation
  徳島
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 新規GATA4結合タンパク質WDR5による心筋細胞肥大反応抑制機構の解析2016
- Author(s)
  天野七菜、刀坂泰史、永井陽介、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第2回J-ISCP学術集会
- Place of Presentation
  徳島
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] RACK1のチロシンリン酸化は心肥大反応を促進する2016
- Author(s)
  宮崎雄輔、刀坂泰史、砂川陽一、船本雅文、和田弘道、長谷川浩二、森本達也
- Organizer
  日本薬学会東海支部大会合同学術大会2016
- Place of Presentation
  岐阜
- Year and Date
  2016-10-30
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] PRMT5特異的阻害剤はp300のメチル化を抑制することで心筋細胞肥大を制御する2016
- Author(s)
  筒井優介、刀坂泰史、宮崎雄輔、北條祐也、砂川陽一、和田啓道、長谷川浩二、森本達也
- Organizer
  第135回日本薬理学会関東部会
- Place of Presentation
  静岡
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] アルギニンメチルトランスフェラーゼPRMT5はp300をメチル化することで心筋細胞肥大を抑制する2016
- Author(s)
  宮﨑雄輔、刀坂泰史、北條祐也、砂川陽一、船本雅文、和田啓道、長谷川浩二、森本達也
- Organizer
  Molecular Cardiovascular Conference II　2016
- Place of Presentation
  東京
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] EPZ015666, a specific PRMT5 inhibitor, represses PE-induced cardiomyocyte hypertrophy2016
- Author(s)
  Hiroki Honda, Yasufumi Katanasaka, Yusuke Miyazaki, Yoichi Sunagawa, Hiromichi Wada, Akira Shimazu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第11回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Heart-specific PRMT5 overexpression accelerates pressure overload-induced cardiac hypertrophy and heart failure2016
- Author(s)
  Hiroki Wakabayashi, Yasufumi Katanasaka, Ryoga Sakurai, Yoichi Sunagawa, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第33回国際心臓研究学会日本部会（ISHR2016）
- Place of Presentation
  東京
- Year and Date
  2016-12-16
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Molecular Pathogenesis of Ventricular Hypertrophy2016
- Author(s)
  Tatsuya Morimoto,Yoichi Sunagawa,Yasufumi Katanasaka, Koji Hasegawa
- Organizer
  International Society of Cardiomyopathies and Heart Failure Congress 2016
- Place of Presentation
  京都
- Year and Date
  2016-12-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] アルギニンメチル化酵素PRMT5は老化における心機能低下を促進する2015
- Author(s)
  若林弘樹、刀坂泰史、櫻井涼賀、砂川陽一、和田啓道、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  愛知
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心不全時におけるp300によるヒストンアセチル化を介したエピジェネティックな転写制御機構の解析2015
- Author(s)
  船本雅文、砂川陽一、清水果奈、刀坂泰史、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  愛知
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心臓特異的転写因子GATA4の二量体化部位の同定とアセチル化の意義について2015
- Author(s)
  依光奈津美、砂川陽一、羽鹿成人、刀坂泰史、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Transcriptional Epigenetic Mechanisms Via Histone Acetylation By p300 During The Development Of Cardiomyocyte Hypertrophy And Heart Failure2015
- Author(s)
  Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第19回日本心不全学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心臓老化に伴う核内転写機能の解明2015
- Author(s)
  野村幸弘、刀坂泰史、砂川陽一、和田啓道、津島章、長谷川浩二、森本達也:心臓老化に伴う核内転写機能の解明
- Organizer
  第15回日本抗加齢医学会総会
- Place of Presentation
  福岡
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] WDR5はp300/GATA4経路を介した心肥大反応遺伝子の転写を抑制した2015
- Author(s)
  天野七菜、刀坂泰史、永井陽介、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  愛知
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] PRMT5 deteriorates left ventricular systolic function with aging2015
- Author(s)
  Hiroki Wakabayashi, Ryoga Sakurai, Yasufumi Katanasaka, Yusuke Miyazaki, Yoichi Sunagawa, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第20回静岡健康・長寿学術フォーラムポスターセッション
- Place of Presentation
  静岡
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] PRMT5 accelerates cardiac hypertrophy and the deterioration of left ventricular systolic function with aging2015
- Author(s)
  Hiroki Wakabayashi, Ryoga Sakurai, Yasufumi Katanasaka, Yusuke Miyazaki, Yoichi Sunagawa, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第32回　ISHR日本部会総会
- Place of Presentation
  神戸
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心不全時におけるp300によるヒストンアセチル化のエピジェネティックな制御機構の解析2015
- Author(s)
  船本雅文、砂川陽一、刀坂泰史、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] The Change of Histone Acetylation by p300 in the Transition from Cardiac Hypertrophy to Chronic Heart Failure2015
- Author(s)
  Kana Shimizu, Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto,
- Organizer
  第20回静岡健康・長寿学術フォーラムポスターセッション
- Place of Presentation
  静岡
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心不全時におけるp300によるヒストンアのセチル化を介したエピジェネティックな制御機構2015
- Author(s)
  船本雅文、砂川陽一、刀坂泰史、鈴木秀敏、和田啓道、長谷川浩二、森本達也
- Organizer
  第15回日本抗加齢医学会総会
- Place of Presentation
  福岡
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心筋細胞肥大に対する新規GATA4結合分子WDR5の機能解析2015
- Author(s)
  永井陽介、刀坂泰史、天野七菜、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  愛知
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] State of The Art: The Role of Molecular Biology in Cardiology2015
- Author(s)
  Tatsuya Morimoto
- Organizer
  THE 24th ANNUAL SCIENTIFIC MEETING of THE INDONESIAN HEART ASSOCIATION
- Place of Presentation
  Jakarta, Indonesia
- Year and Date
  2015-04-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] RMT5/MEP50メチル化複合体による心筋細胞肥大制御機構の解析2015
- Author(s)
  刀坂泰史、中田淳也、宮崎雄輔、砂川陽一、鈴木秀敏、和田啓道、長谷川浩二、森本達也
- Organizer
  第61回　日本薬学会東海支部大会
- Place of Presentation
  愛知
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] RACK1によるp300/GATA4経路を介した心肥大反応抑制機構の解析2015
- Author(s)
  鈴木秀敏、砂川陽一、刀坂泰史、宮崎雄輔、船本雅文、和田啓道、長谷川浩二、森本達也
- Organizer
  第61回　日本薬学会東海支部大会
- Place of Presentation
  愛知
- Year and Date
  2015-07-04
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心肥大反応における新規GATA4結合タンパク質WDR5の機能解析2015
- Author(s)
  天野七菜、刀坂泰史、永井陽介、砂川陽一、鈴木秀敏、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] The Acetylation of GATA4 by p300 Is Required or Homo-dimerization of GATA42015
- Author(s)
  Satoshi Shimizu, Natsumi Yorimitsu, Yoichi Sunagawa, Yasufumi Katanasaka, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第20回静岡健康・長寿学術フォーラムポスターセッション
- Place of Presentation
  静岡
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] ＴＢＬ1/ＨＤＡＣ3複合体による心肥大抑制メカニズムの解析2015
- Author(s)
  筒井優介、小山内崇人、刀坂泰史、永井陽介、砂川陽一、鈴木秀敏、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  愛知
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Transcriptional Epigenetic Mechanisms via Histone Acetylation by p300 in Cardiac Hypertrophy2015
- Author(s)
  Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Hiromichi Wada,　Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第79回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-25
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心臓老化に伴う核内転写機能の解明2015
- Author(s)
  野村幸弘、刀坂泰史、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 圧負荷心肥大モデルマウスにおけるPRMT5の機能解析2015
- Author(s)
  櫻井涼賀、刀坂泰史、若林弘樹、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  愛知
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Updates in management of diastolic left ventricular failure: Recent Complimentary Evidence2015
- Author(s)
  Tatsuya Morimoto
- Organizer
  THE 24th ANNUAL SCIENTIFIC MEETING of THE INDONESIAN HEART ASSOCIATION
- Place of Presentation
  Jakarta, Indonesia
- Year and Date
  2015-04-11
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] TBL1/HDAC3 complex inhibits cardiomyocyte hypertrophy by regulating the association with p300/GATA4 complex (*)2015
- Author(s)
  Yusuke Tsutsui, Yasufumi Katanasaka, Yosuke Nagai, Yoichi Sunagawa, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第20回静岡健康・長寿学術フォーラムポスターセッション
- Place of Presentation
  静岡
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] TBL1による心筋細胞抑制にはHDAC3が必要である2015
- Author(s)
  永井陽介、刀坂泰史、小山内崇人、砂川陽一、鈴木秀敏、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Protein Arginine Methyltransferase 5/Methylosome Protein 50 Complex Inhibits p300 Histone Acetyltransferase Activity and Hypertrophic Gene transcription in Cultured Cardiomyocytes2015
- Author(s)
  Yusuke Miyazaki, Yasufumi Katanasaka, Yoichi Sunagawa, Hiromichi Wada, Koji Hasegawa and Tatsuya Morimoto
- Organizer
  AHA Scientific Sessions 2015
- Place of Presentation
  Orlando,USA
- Year and Date
  2015-11-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] RACK1によるp300/GATA4経路を介した心肥大反応抑制機構の解析2015
- Author(s)
  鈴木秀敏、砂川陽一、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] MEP50 inhibites p300/GATA4-induced hypertrophic gene transcription by recruiting PRMT5 to p3002015
- Author(s)
  Yusuke Tsutsui, Yusuke Miyazaki, Yasufumi Katanasaka, Ryoga Sakurai, Yoichi Sunagawa, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第32回　ISHR日本部会総会
- Place of Presentation
  兵庫
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] アルギニンメチル化酵素ＰＲＭT5はヒストンアセチル化酵素ｐ300をメチル化する2015
- Author(s)
  北条祐也、刀坂泰史、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  愛知
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心臓特異的転写因子GATA4の二量体化部位の同定とアセチル化の意義の解明2015
- Author(s)
  依光奈津美、砂川陽一、船本雅文、刀坂泰史、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  愛知
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] A Transcriptional Co-activator, p300 is Involved in the Epigenetic Gene Activation on Hypertrophic Response Gene Promoters during Cardiomyocyte Hypertrophy2015
- Author(s)
  Masafumi Funamoto, Yoichi Sunagawa, Yasufumi Katanasaka, Hiromichi Wada、Koji Hasegawa, Tatsuya Morimoto
- Organizer
  20th Annual Scientific Meeting of the International Society of Cardiovascular Pharmacotherapy
- Place of Presentation
  Buenos Aires, Argentina
- Year and Date
  2015-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心不全の情報伝達機構p300/GATA4複合体の解析2015
- Author(s)
  森本達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] MEP50による心肥大転写反応の調節2015
- Author(s)
  宮﨑雄輔、刀坂泰史、櫻井涼賀、若林弘樹、砂川陽一、鈴木秀敏、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 培養心筋細胞においてPRMT5はp300をメチル化することにより心肥大反応を抑制2015
- Author(s)
  北條祐也、刀坂泰史、中田敦也、砂川陽一、鈴木秀敏、長谷川浩二、森本達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心筋細胞肥大におけるTBL1/HDAC3複合体の機能解析2015
- Author(s)
  刀坂泰史、小山内崇人、永井陽介、砂川陽一、鈴木秀敏、和田啓道、長谷川浩二、森本達也
- Organizer
  第15回日本抗加齢医学会総会
- Place of Presentation
  福岡
- Year and Date
  2015-05-29
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心不全における閣内情報伝達経路の役割2015
- Author(s)
  森本達也
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  愛知
- Year and Date
  2015-03-18
- Invited
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Protein Arginine Methyltransferase 5 Inhibits cardiomyocyte Hypertrophy by methylating p300 in Cultured Cardiomyocytes2015
- Author(s)
  Hiroki Wakabayashi, Yasufumi Katanasaka, Yusuke Miyazaki, Ryoga Sakurai, Yoichi Sunagawa, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  Asian Pacific Society of Cardiology Congress 2015
- Place of Presentation
  Abu Dhabi, UAE
- Year and Date
  2015-05-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] PRMT5心臓特異的過剰発現マウスにおける左心室収縮能への影響2015
- Author(s)
  若林弘樹、刀坂泰史、櫻井涼賀、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] WDR5, a novel GATA4-binding protein, suppresses p300/GATA4-dependent gene transcription2014
- Author(s)
  Nana Amano, Yasufumi Katanasaka, Yosuke Nagai, Yoichi Sunagawa, Hidetoshi Suzuki, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第19回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Protein Arginine Methyltransferase 5 Methylates p300 and Inhibits Hypertrophic Responses in Cultured Cardiomyocytes2014
- Author(s)
  Yuya Hojo, Tatsuya Morimoto, Yasufumi Katanasaka, Junya Nakada, Yoichi Sunagawa, Hidetoshi Suzuki, Koji Hasegawa
- Organizer
  第31回国際心臓研究学会（ISHR）日本部会総会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-28
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Heart-specific PRMT5 overexpression promotes cardiac hypertrophy in mice2014
- Author(s)
  Yusuke Miyazaki, Yasufumi Katanasaka, Ryoga Sakurai, Hiroki Wakabayashi, Yoichi Sunagawa, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto, Hidetoshi Suzuki, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第19回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Receptor for Activated Protein Kinase C1 Competes with GATA4 for p300 and Inhibits Hypertrophic Responses in Cardiomyocytes2014
- Author(s)
  Hidetoshi Suzuki, Yoichi Sunagawa, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  American Heart Association Scientific Sessions 2013
- Place of Presentation
  Chicago,USA
- Year and Date
  2014-11-19
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] RbAp48/46 Regulate Hypertrophic Responses Involved in Modulating the Posttranslational Modification of GATA4 during Cardiomyocyte Hypertrophy2014
- Author(s)
  Yoichi Sunagawa, Yasufumi Katanasaka, Hidetoshi Suzuki, Naruto Hajika, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  World Congress of Cardiology Scientific Sessions 2014
- Place of Presentation
  Melboume, Australia
- Year and Date
  2014-05-06
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] HDAC3選択的阻害剤を用いた心筋細胞肥大メカニズムの解析2014
- Author(s)
  刀坂泰史、小山内崇人、永井陽介、砂川陽一、鈴木秀敏、和田啓道、長谷川浩二、森本達也
- Organizer
  第24回日本循環薬理学会
- Place of Presentation
  山形
- Year and Date
  2014-12-05
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] RACK1におけるチロシン残基リン酸化は心筋細胞肥大におけるp300/GATA4経路の活性を制御する2014
- Author(s)
  鈴木秀敏、砂川陽一、刀坂泰史、田中寿樹、和田啓道、長谷川浩二、森本達也
- Organizer
  第5回　Molecular Cardiovascular Conference II
- Place of Presentation
  神戸
- Year and Date
  2014-09-05
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] "PRMT5心臓特異的過剰発現マウスにおける加齢性心肥大への影響2014
- Author(s)
  若林弘樹、刀坂泰史、櫻井涼賀、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心肥大誘導時におけるMEP50の効果の検討2014
- Author(s)
  櫻井涼賀、刀坂泰史、宮崎雄輔、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 新規GATA結合タンパク質TBLIによる心肥大転写反応の抑制2014
- Author(s)
  刀坂泰史、永井陽介、並木雅俊、小山内崇人、砂川陽一、鈴木秀敏、和田啓道、長谷川浩二、森本達也
- Organizer
  第51回日本臨床分子医学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-04-11
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 新規GATA4結合タンパク質PRMT1による心筋細胞肥大反応の抑制2014
- Author(s)
  天野七菜、刀坂泰史、砂川陽一、鈴木秀敏、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] アルギニンメチル化酵素ＰＲＭTによる心肥大反応抑制機構の解析2014
- Author(s)
  中田淳也,刀坂泰史、中川由紀子、砂川陽一、和田啓道、長谷川浩二、森本達也
- Organizer
  第51回日本臨床分子医学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-04-11
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Transducin beta-like protein 1/histone deacetylase 3 form a complex with p300/GATA4 and suppress hypertrophic gene transcription in cardiomyocytes2014
- Author(s)
  Yosuke Nagai, Yasufumi Katanasaka, Takahito Osanai, Yoichi Sunagawa, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第31回国際心臓研究学会（ISHR）日本部会総会
- Place of Presentation
  名古屋
- Year and Date
  2014-11-28
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心肥大反応における新規GATA4結合タンパク質TBLR1の機能解析2014
- Author(s)
  廣田翔、刀坂泰史、並木雅俊、砂川陽一、鈴木秀敏、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Transducin beta-like protein suppresses cardiomyocyte hypertrophy by recruiting HDAC3 to GATA42014
- Author(s)
  Yosuke Nagai, Yasufumi Katanasaka, Nana Amano, Yoichi Sunagawa, Hidetoshi Suzuki, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第19回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] RACK1は心肥大刺激におけるGATA4アセチル化を抑制した2014
- Author(s)
  鈴木秀敏、砂川陽一、刀坂泰史、岡村信子、田中寿樹、北條祐也、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第60回日本薬学会東海支部総会・大会
- Place of Presentation
  三重
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心肥大反応抑制遺伝子ＲＡＣK1とＧＡＴＡ4の結合部位の同定2014
- Author(s)
  田中寿樹、鈴木秀敏、刀坂泰史、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] TBL1/HDAC3複合体による心肥大抑制メカニズムの解析2014
- Author(s)
  小山内崇人、刀坂泰史、永井陽介、砂川陽一、鈴木秀敏、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] TBL1はHDAC3を介して心筋細胞肥大を抑制した2014
- Author(s)
  永井陽介、小山内崇人、刀坂泰史、砂川陽一、鈴木秀敏、和田啓道、長谷川浩二、森本達也
- Organizer
  第5回　Molecular Cardiovascular Conference II
- Place of Presentation
  神戸
- Year and Date
  2014-09-05
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 新規GATA4結合タンパク質WDR5によるp300/GATA4経路への影響2014
- Author(s)
  永井陽介、刀坂泰史、天野七菜、砂川陽一、鈴木秀敏、和田啓道、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] MEP50によるp300/GATA4転写経路調節機構2014
- Author(s)
  宮崎雄輔、刀坂泰史、櫻井涼賀、砂川陽一、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 新規GATA4結合タンパク質MEP50の心肥大に対する機能解析2014
- Author(s)
  櫻井涼賀、刀坂泰史、宮崎雄輔、中田淳也、砂川陽一、鈴木秀敏、和田啓道、長谷川浩二、森本達也
- Organizer
  第5回　Molecular Cardiovascular Conference II
- Place of Presentation
  神戸
- Year and Date
  2014-09-05
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心肥大反応遺伝子転写抑制におけるＰＲＭT5のもつメチル化活性の影響2014
- Author(s)
  中田淳也、刀坂泰史、北條祐也、砂川陽一、鈴木秀敏、和田啓道、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] PRMT5によるp300のメチル化とその機能解析2014
- Author(s)
  北條祐也、刀坂泰史、中田淳也、砂川陽一、鈴木秀敏、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Methylosome protein 50 promoted the association of Protein arginine methyltransferase 5 with p3002014
- Author(s)
  Yusuke Miyazaki, Yasufumi Katanasaka, Yukiko Nakagawa, Yoichi Sunagawa, Junya Nakada, Hidetoshi Suzuki, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  World Congress of Cardiology Scientific Sessions 2014
- Place of Presentation
  Melboume, Australia
- Year and Date
  2014-05-05
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Protein Arginine Methyltransferase 5 regulates hypertrophic gene transcription by methylation of p3002014
- Author(s)
  Yuya Hojo, Yasufumi Katanasaka, Junya Nakada, Yoichi Sunagawa, Hidetoshi Suzuki, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第19回静岡健康・長寿学術フォーラム
- Place of Presentation
  静岡
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 心肥大反応における新規GATA4結合タンパク質PRMT5の機能解析2014
- Author(s)
  北條祐也、刀坂泰史、中川由紀子、宮崎雄輔、中田淳也、砂川陽一、鈴木秀敏、和田啓道、長谷川浩二、森本達也
- Organizer
  第5回　Molecular Cardiovascular Conference II
- Place of Presentation
  神戸
- Year and Date
  2014-09-05
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] A noble heart failure therapy targeting transcriptional pathways in cardiomyocytes2014
- Author(s)
  Tatsuya Morimoto, Yoichi Sunagawa, Yasufumi Katanasaka, Koji Hasegawa
- Organizer
  The 2nd International Conference on Pharma-Food (ICPF 2014)
- Place of Presentation
  静岡
- Year and Date
  2014-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] HDAC3 activity is necessary for anti-hypertrophic effect of TBL12014
- Author(s)
  Takahito Osanai, Yasufumi Katanasaka, Yosuke Nagai, Yoichi Sunagawa, Hidetoshi Suzuki, Hiromichi Wada, Akira Shimatsu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 2nd International Conference on Pharma-Food (ICPF 2014)
- Place of Presentation
  静岡
- Year and Date
  2014-11-06
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] RACK1によるp300/GATA4経路を介した心肥大反応抑制機構の解析2014
- Author(s)
  鈴木秀敏、砂川陽一、刀坂泰史、田中寿樹、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2014
- Place of Presentation
  静岡
- Year and Date
  2014-11-09
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Retinoblastoma Protein (Rb)-associated Protein 48 and 46, Novel p300/GATA4-binding Partners, Inhibits Hypertrophic Responses in Cardiomyocytes2012
- Author(s)
  Yoichi Sunagawa, Yuichi Watanabe, Hidetoshi Suzuki, Yasufumi Katanasaka, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2012-03-17
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Human SNF5/INI1, a Component of the Human SWI/SNF Chromatin Remodeling Complex, Inhibits Hypertrophic Responses by Suppressing p300/GATA4-dependent Pathways in Cardiomyocytes2012
- Author(s)
  Yoichi Sunagawa, Yukihiro Ishibashi, Natsumi Banno, Yasufumi Katanasaka, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2012-03-17
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Transducin Beta-like Protein 1 Suppresses Hypertrophic Responses Through Repression of p300/GATA4 Pathway in Cardiomyocytes2012
- Author(s)
  Masatoshi Namiki, Yasufumi Katanasaka, Yoichi Sunagawa, Hidetoshi Suzuki, Sho Hirota, Yukiko Nakagawa, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Protein Arginine Methyltransferase 5 and Methylosome Protein 50 Suppressies Hypertrophic Responses in Cardiomyocytes by Inhibition of p300/GATA4 Pathway2011
- Author(s)
  Yasufumi Katanasaka, Yukiko Nakagawa, Yoichi Sunagawa, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  American Heart Association Scientific sessions 2011
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Receptor for Activated Protein Kinase C1 is a novel component of p300/GATA4 complex and required for hypertrophic responses in cardiac myocytes2011
- Author(s)
  Hidetoshi Suzuki, Yoichi Sunagawa, Yasufumi Katanasaka, Nobuko Okamura, Taishi Terada, Masatoshi Namiki, Yukiko Nakagawa, Akihisa Sugimoto, Hiromichi Wada, Akira Shimatsu, Takeshi Kimura, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第28回国際心臓研究学会(ISHR)日本部会総会
- Place of Presentation
  東京
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Protein arginine ethyltransferase 5 suppresses hypertrophic gene transcription in rat cardiomyocytes through the inhibition of P300/GATA4 pathway2011
- Author(s)
  Yasufumi Katanasaka, Yukiko Nakagawa, Yoichi Sunagawa, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 7th Chica-Japan Cardiovascular Forum
- Place of Presentation
  Beijing, China
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Transducin beta-like protein 1 inhibits hypertrophic responses by recruiting HDAC3 to p300/GATA4 pathways2011
- Author(s)
  Masatoshi Namiki, Yasufumi Katanasaka, Yoichi Sunagawa, Hidetoshi Suzuki, Sho Hirota, Taishi Terada, Yukiko Nakagawa, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 7th Chica-Japan Cardiovascular Forum
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Protein arginine metyltransferase 5 and methylosome protein 50 are novel component of P300/GATA4 complex involved in hypertrophic responses in cardiac myocytes2011
- Author(s)
  Yasufumi Katanasaka, Yukiko Nakagawa, Yoichi Sunagawa, Masatoshi Fujita, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 14 th Annual International Tronto Heart Summit
- Place of Presentation
  Tronto, Canada
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Protein arginine metyltransferase 5 and methylosome protein 50 are novel component of p300/GATA4 complex involved in hypertrophic responses in cardiac myocytes2011
- Author(s)
  Yasufumi Katanasaka, Yukiko Nakagawa, Yoichi Sunagawa, Masatoshi Fujita, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 14th Annual International Tronto Heart Summit
- Place of Presentation
  Tronto, Canada
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Retinoblastoma protein (Rb)-associated protein 48 and 46 are novel p300/GATA4-binding partners involved in hypertrophic responses in cardiomyocytes2011
- Author(s)
  Yoichi Sunagawa, Yasufumi Katanasaka, Taishi Terada, Yuichi Watanabe, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  American Heart Association BCVS2011
- Place of Presentation
  New Orleans, USA
- Year and Date
  2011-07-20
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] SNF5/INI1 Inhibits Hypertrophic Responses by Suppressing p300/GATA4-dependent Pathways in Cardiomyocytes2011
- Author(s)
  Yoichi Sunagawa, Sugimoto Akihisa, Yukihiro Ishibashi, Yasufumi Katanasaka, Hiromichi Wada, Akira Shimatsu, Takeshi Kimura, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  American Heart Association Scientific Sessions 2011
- Place of Presentation
  Orland, USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Retinoblastoma protein (Rb)-associated protein 48 and 46 are novel p300/GATA4-binding partners involved in hypertrophic responses in cardiomyocytes2011
- Author(s)
  Yoichi Sunagawa, Yasufumi Katanasaka, Taishi Terada, Yuichi Watanabe, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第15回日本心不全学会学術集会会
- Place of Presentation
  鹿児島
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] SNF5/INI1 Inhibits Hypertrophic Responses by Suppressing p300/GATA4-dependent Pathways in Cardiomyocytes2011
- Author(s)
  Yoichi Sunagawa, Sugimoto Akihisa, Yukihiro Ishibashi, Yasufumi Katanasaka, Hiromichi Wada, Akira Shimatsu, Takeshi Kimura, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  American Heart Association Scientific sessions 2011
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] 新しい心不全分子標的治療2011
- Author(s)
  森本達也、長谷川浩二
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Retinoblastoma protein (Rb)-associated protein 48 and 46 are novel components of p300/GATA4 complex required for hypertrophic responses in cardiomyocytes2011
- Author(s)
  Yoichi Sunagawa, Yasufumi Katanasaka, Taishi Terada, Yuichi Watanabe, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 14 th Annual International Tronto Heart Summit
- Place of Presentation
  Tronto, Canada
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Retinoblastoma Protein (Rb)-associated Protein 48 and 46 Form a Functional Complex With p300/GATA4 and Suppress Hypertrophic Responses in Cardiomyocytes2011
- Author(s)
  Yoichi Sunagawa, Yasufumi Katanasaka, Taishi Terada, Yuichi Watanabe, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  American Heart Association Scientific Sessions 2011
- Place of Presentation
  Orland, USA
- Year and Date
  2011-11-15
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Transducin beta-like protein 1 suppresses p300/GATA4-induced hypertrophic responses in cardiomyocytes2011
- Author(s)
  Masatoshi Namiki, Yasufumi Katanasaka, Yoichi Sunagawa, Hidetoshi Suzuki, Sho Hirota, Taishi Terada, Yukiko Nakagawa, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第28回国際心臓研究学会(ISHR)日本部会総会
- Place of Presentation
  東京
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] A p300/GATA4 Transcriptional Pathway that Induces the Development of Heart Failure2011
- Author(s)
  Tatsuya Morimoto, Koji Hasegawa
- Organizer
  The 7th Chica-Japan Cardiovascular Forum
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Protein Arginine Methyltransferase 5 and Methylosome Protein 50 Suppressies Hypertrophic Responses in Cardiomyocytes by Inhibition of p300/GATA4 Pathway2011
- Author(s)
  Yasufumi Katanasaka, Yukiko Nakagawa, Yoichi Sunagawa, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  American Heart Association Scientific Sessions 2011
- Place of Presentation
  Orland, USA
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Retinoblastoma protein(Rb)-associated protein 48 and 46 are novel p300/GATA4-binding partners involved in hypertrophic responses in cardiomyocytes2011
- Author(s)
  Yoichi Sunagawa, Yasufumi Katanasaka, Taishi Terada, Yuichi Watanabe, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  American Heart Association BCVS2011
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Retinoblastoma Protein(Rb)-associated Protein 48 and 46 are Novel Components of p300/GATA4 Complex Required for Hypertrophic Responses in Cardiomyocytes2011
- Author(s)
  Yoichi Sunagawa, Yasufumi Katanasaka, Taishi Terada, Yuichi Watanabe, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 14th Annual International Tronto Heart Summit
- Place of Presentation
  Tronto, Canada
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] A P300/GATA4 transcriptional pathway that induces the development of heart failure2011
- Author(s)
  Tatsuya Morimoto, Koji Hasegawa
- Organizer
  The 7th Chica-Japan Cardiovascular Forum
- Place of Presentation
  Beijing, China
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Protein arginine metyltransferase 5 and methylosome protein 50 are novel component of p300/GATA4 complex involved in hypertrophic responses in cardiac myocytes2011
- Author(s)
  Yasufumi Katanasaka, Yukiko Nakagawa, Yoichi Sunagawa, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  American Heart Association BCVS2011
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Retinoblastoma Protein(Rb)-associated Protein 48 and 46 Form a Functional Complex With p300/GATA4 and Suppress Hypertrophic Responses in Cardiomyocytes2011
- Author(s)
  Yoichi Sunagawa, Yasufumi Katanasaka, Taishi Terada, Yuichi Watanabe, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  American Heart Association Scientific sessions 2011
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Protein arginine ethyltransferase 5 suppresses hypertrophic gene transcription in rat cardiomyocytes through the inhibition of p300/GATA4 pathway2011
- Author(s)
  Yasufumi Katanasaka, Yukiko Nakagawa, Yoichi Sunagawa, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 7th Chica-Japan Cardiovascular Forum
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Receptor for activated protein kinase C1 is a novel component of p300/GATA4 complex and suppresses hypertrophic responses in cardiomyocytes2011
- Author(s)
  Hidetoshi Suzuki, Yoichi Sunagawa, Yasufumi Katanasaka, Nobuko Okamura, Taishi Terada, Masatoshi Namiki, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 7th Chica-Japan Cardiovascular Forum
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Cdk9 kinase activity is required for p300 phosphorylation and regulate transcriptional pathway during hypertrophic responses in cardiomyocytes2009
- Author(s)
  Taishi Terada, Tatsuya Morimoto, Yoichi Sunagawa, Masatoshi Fujita, Takeshi KimuraKoji Hasegawa
- Organizer
  The 5th China-Japan Cardiovascular Forum
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] A natural p300-specific histone acetyltransferase inhibitor, curcumin, exerts synergistic effects with ACE inhibitor during systolic function restoration after myocardial infarction in rats2009
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Hiromichi Wada, Tomohide Takaya, Teruhisa Kawamura, Shigeki Yanagi, Akira Marui, Tadashi Ikeda, Ryuzo Sakata, Akira Shimatsu, Takeshi Kimura, Masatoshi FujitaKoji Hasegawa
- Organizer
  The 82th American Heart Association Annual Scientific Sessions
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Heart failure therapy that targets nuclear signaling pathway in cardio myocytes- from bench to bedside2009
- Author(s)
  森本達也
- Organizer
  The 26th Annual Meeting of ISHR Japanese Section
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] A natural p300-specific histone acetyltransferase inhibitor, Curcumin, can prevent the development of heart failure in addition to ACE inhibitor after myocardial infarction in rats2009
- Author(s)
  森本達也
- Organizer
  European Society of Cardiology(ESC)Congress
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Cyclin-dependent kinase-9 is Recruited on Cardiac Hypertrophic Response Gene Promoters through GATA4 in Cardiomyocytes2009
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Toru Kita, Koji Hasegawa
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Serum Levels of Oxidized Low-density Lipoprotein Decrease during Successful Smoking Cessation2009
- Author(s)
  Hiromichi Wada, Noriko Satoh, Shuji Kitaoka, Sachiko Terashima, Tatsuya Morimoto, Masatoshi Fujita, Akira Shimatsu, Yuko Takahashi, Koji Hasegawa
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Heart f ailure therapy that targets nuclear signaling pathway in cardiomyocytes. from bench to bedside2009
- Author(s)
  Tatsuya MorimotoKoji Hasegawa
- Organizer
  The 25th Annual Meeting of ISHR Japanese Section, Scientific Program
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Curcumin Prevents the Development of Hypertension-induced Left Ventricular Hypertrophy in Rats2009
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Kazuhide Uemura, Akira Shimatsu, Takeshi Kimura, Masatoshi FujitaKoji Hasegawa
- Organizer
  The 82th American Heart Association Annual Scientific Sessions
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] A Natural p300-specific HAT Inhibitor, Curcumin, Possesses Beneficial Effects in Addition to ACE Inhibitor after Rat Myocardial Infarction2009
- Author(s)
  森本達也
- Organizer
  17^<th> Asian Pacific Congress of Cardiology(APCC)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] A Natural p300-specific HAT Inhibitor, Curcumin, Possesses Beneficial Effects in Addition to ACE Inhibitor after Rat Myocardial Infarction2009
- Author(s)
  Tatsuya Morimoto, Yoichi Sunagawa, Hiromichi Wada, Tomohide Takaya, Shigeki Yanagi, Akihiro Sugimoto, Masaki Tsukashita, Akira Marui, Tadashi Ikeda, Masatoshi Fujita, Akira Shimatsu, Toru KitaKoji Hasegawa
- Organizer
  17th Asian Pacific Congress of Cardiology
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] A natural p300-specific histone acetyltransferase inhibitor, Curcumin, can prevent the development of heart failure in addition to ACE inhibitor after myocardial infarction in rats2009
- Author(s)
  Tatsuya Morimoto, Masatoshi Fujita, Yoichi Sunagawa, Hiromichi Wada, Tomohide Takaya, Shigeki Yanagi, Akira Marui, Tadashi Ikeda, Akira ShimatsuKoji Hasegawa
- Organizer
  European Society of Cardiology Congress
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Cell Line-dependent Differentiation of Mouse Induced-pluripotent Stem Cells into Cardiomyocytes2009
- Author(s)
  Shinji Kaichi, Tomohide Takaya, Tatsuya Morimoto, Yoichi Sunagawa, Teruhisa Kawamura, Koh Ono, Toru Kita, Kyoko Hidaka, Takayuki Morisaki, Shiro Baba, Toshio Heike, Tatsutoshi Nakahata, Koji Hasegawa
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Self-rating Depression Scale score is a Strong Independent Predictor of Smoking Cessation Outcomes2009
- Author(s)
  Hiromichi Wada, Koji Hasegawa, Sachiko Terashima, Noriko Satoh, Misuzu Inoue, Yuko Iida, Hajime Yamakage, Shuji Kitaoka, Tatsuya Morimoto, Masatoshi Fujita, Akira Shimatsu, Yuko Takahashi
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Curcumin exerts synergistic effects with ACE inhibitor during LV systolic function restoration after rat myocardial infarction2009
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Tomohide Takaya, Masatoshi Fujita, Takeshi KimuraKoji Hasegawa
- Organizer
  The 5th China-Japan Cardiovascular Forum
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Cell Line-dependent Differentiation of Mouse Induced-pluripotent Stem Cells into Cardiomyocytes2009
- Author(s)
  Shinji Kaichi, Tomohide Takaya, Tatsuya Morimoto, Yoichi Sunagawa, Teruhisa Kawamura, Koh Ono, Toru Kita, Kyoko Hidaka, Takayuki Morisaki, Shiro Baba, Toshio Heike, Tatsutoshi Nakahata, Koji Hasegawa
- Organizer
  臨床心血管再生研究会
- Place of Presentation
  京都
- Year and Date
  2009-03-04
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Novel drug-delivery system of oral curcumin that prevents the deterioration of systolic function after myocardial infarction in rats2009
- Author(s)
  Yoichi Sunagawa, Hiroyuki Fukuda, Hiromichi Wada, Tomohide Takaya, Akira Marui, Kazuhide Uemura, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 82th American Heart Association Annual Scientific Sessions
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Synergistic Effects of G-CSF and Erythropoietin on Left Ventricular Systolic Function in Heart Failure after Rat Myocardial Infarction2009
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Teruhisa Kawamura, Tomohide Takaya, Hiromicht Wada, Tomoaki Kuwaki, Shigeki Yanagi, Akihiro Sugimoto, Masaki Tsukashita, Akira Marui, Tadashi Ikeda, Akira Shimatsu, Masatoshi Fujita, Toru Kita, Koji Hasegawa
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Serum Levels of Soluble VEGF Receptor-2 Decrease during Successful Smoking Cessation2009
- Author(s)
  Hiromichi Wada, Noriko Satoh, Shuji Kitaoka, Sachiko Terashima, Tatsuya Morimoto, Masatoshi Fujita, Akira Shimatsu, Yuko Takahashi, Koji Hasegawa
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] A novel component of p300/GATA4 complex, Cyclin-dependent kinsase-9, is required for hypertrophic responses in cardiomyocytes2009
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Masatoshi FujitaKoji Hasegawa
- Organizer
  The 25th Annual Meeting of ISHR Japanese Section Scientific Program
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Left ventricular expression of lectin-like oxidized low-density lipoprotein receptor-1 during the development of heart failure2009
- Author(s)
  Takaya T, Morimoto T, Sungawa Y, Wada H, Kawamura T, Shimatsu A, Fujita M, Fujita Y, Sawamura T, Hasegawa K
- Organizer
  第73回日本循環器学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 天然成分クルクミンを用いた新規心不全治療の基盤研究2009
- Author(s)
  砂川陽一, 森本達也, 藤田, 正俊, 長谷川浩二
- Organizer
  臨床心血管再生研究会
- Place of Presentation
  京都
- Year and Date
  2009-03-04
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 天然クルクミン2g/日は、有効な血中クルクミン濃度となる2009
- Author(s)
  森本達也
- Organizer
  第13回 Molecular Cardiovascular Conference
- Place of Presentation
  北海道
- Data Source
  KAKENHI-PROJECT-21590944
[Presentation] Synergistic Effects of Granulocyte-colony stimulating factor and Erythropoietin on Left Ventricular Systolic Function in Rat Myocardial Infarction2008
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Tomoaki Kuwaki, Shigeki Yanagi, Akihiro Sugimoto, Masaki Tsukashita, Akira Marui, Tadashi Ikeda, Akira Shimatsu, Masatoshi Fujita, Tom Kita, Koji Hasegawa
- Organizer
  第12回日本心不全学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 禁煙が血管新生関連因子の血消レベルに及ぼす影響2008
- Author(s)
  和田啓道, 佐藤哲子, 北岡修二, 寺嶋幸子, 森本達也, 藤田正俊, 島津章, 高橋裕子, 長谷川浩二
- Organizer
  第3回禁煙科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Cyclin-dependent Kinase-9, As A Novel Component Of p300/GATA4 Complex, Is Involved In The Differentiation Of Mouse ES Cells Into Cardiac Myocytes2008
- Author(s)
  S Kaichi, T Takaya, T Morimoto. Y Sunagawa, T Kawamura, K Ono, T Kita, T Heike, T Nakahata, K Hasegawa
- Organizer
  第72回日本循環器学会
- Place of Presentation
  博多、福岡
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Curcumin, a Natural p300-specific Histone Acetyltransferase Inhibitor, Prevents the Development of Heart Failure in Rats2008
- Author(s)
  Tatsuya Morimoto, Yoichi Sunagawa, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Shoichi Miyamoto, Atsushi Nagasawa, Shigeki Yanagi, Ryota Sugimoto, Akira Marui, Masashi Komeda, Masatoshi Fujita, Akira Shimatsu, Toru Kita, Koji Hasegawa
- Organizer
  Keystone Symposia
- Place of Presentation
  Colorado, USA
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] メタボリックシンドロームの心血管合併症における可溶性血管内皮増殖因子受容体2の意義2008
- Author(s)
  和田啓道, 佐藤哲子, 尾野亘, 新城大輔, 森本達也, 中野為夫, 島津章, 藤田正俊, 長谷川浩二
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Cyclin dependent kinase-9 is required for histone acetyltransferase activity of p300 during cardiomyocyte hypertrophy2008
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Toru Kita, Koji Hasegawa
- Organizer
  The 4th China-Japan Cardiovascular Forum(CJCF)
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Cyclin-dependent Kinase-9, As A Novel Component Of p300/GATA4 Complex, Is Involved In The Differentiation Of Mouse ES Cells Into Cardiac Myocytes2008
- Author(s)
  S Kaichi, T Takaya, T Morimoto. Y Sunagawa, T Kawamura, K Ono, T Kita, T Heike, T Nakahata, K Hasegawa
- Organizer
  BIT Life Sciences' 1st Annual World Congress of Regenerative Medicine & Stem Cell
- Place of Presentation
  Guangzhou, China
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Left ventricular expression of lectin-like oxidized low-density lipoprotein receptor-1 serves as a biomarker of heart failure in the salt-sensitive Dahl rat model of hypertension2008
- Author(s)
  Tomohide Takaya, Tatsuva Morimoto. Yoichi Sunagawa, Hiromichi Wada, Teruhisa Kawamura, Akira Shimatsu, Masatoshi Fujita, Yoshiko Fujita, Tatsuya Sawamura, Koji Hasegawa
- Organizer
  The 81^<th> American Heart Association Annual Scientific Sessions
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Cdk9はp300のリン酸化やGATA4のアセチル化を亢進し、心筋細胞肥大反応に必要である2008
- Author(s)
  砂川陽一, 森本達也, 高谷智英, 和田啓道, 川村晃久, 藤田正俊, 島津章, 北徹, 長谷川浩二
- Organizer
  第45回日本臨床分子医学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 天然成分クルクミンを用いた新規心不全治療2008
- Author(s)
  森本達也
- Organizer
  平成19年度臨床心血管再生研究会
- Place of Presentation
  京都
- Year and Date
  2008-01-31
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] The kinase activity of cyclin-dependent kinase-9 is required for phosphorylation of p300 and acetylation of GATA4 as well as cardiomyocyte hypertrophy2008
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Tomohide Takaya, Teruhisa Kawamura, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Toru Kita, Koji Hasegawa
- Organizer
  第12回日本心不全学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Cycltn-dependent Kinase-9はp300のHistone Acetyltransferase活性に必須である2008
- Author(s)
  砂川陽一, 森本達也, 長谷川浩二
- Organizer
  第3回京滋ハートセミナー
- Place of Presentation
  京都
- Year and Date
  2008-04-17
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] A non-toxic dietary compound curcumin provides a novel heart failure therapy that targets nuclear signaling pathway in cardiac myocytes2008
- Author(s)
  Tatsuya Morimoto
- Organizer
  第72回日本循環器学会
- Place of Presentation
  博多
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] The kinase activity of cyclin-dependent kinase-9 is required for phosphorylation of p300 and its histone acetyltransferase activity during cardiomyocyte hypertrophy2008
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Tomohide Takaya, Teruhisa Kawamura, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Toru Kita, Koji Hasegawa
- Organizer
  The 81^<th> American Heart Association Annual Scientific Sessions
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] A non-toxic dietary compound curcumin provides a novel heart failure therapy that targets nuclear signaling pathway in cardiac myocytes2008
- Author(s)
  Tatsuya Morimoto, Masatoshi Fujita, Akira Shimatsu Akira, Tom Kita, Koji Hasegawa
- Organizer
  第72回日本循環器学会
- Place of Presentation
  博多、福岡
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] G-CSF/エリスロポエチン併用療法はラット心筋梗塞後の左室機能低下を改善する2008
- Author(s)
  森永智子, 森本達也, 砂川陽一, 高谷智英, 桑木知朗, 柳茂樹, 杉本亮大, 塚下将樹, 丸井晃, 池田義, 川村晃久, 和田啓道, 島津章, 長谷川浩二, 藤田正俊
- Organizer
  第12回 Molecular Cardiovascular Conference
- Place of Presentation
  キロロ
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Curcumin Reverses the Hypertension-induced Left Ventricular Concentric Remodeling in Rats2008
- Author(s)
  Tatsuya Morimoto, Yoichi Sunagawa, Tomohide Takaya, Toru Kita, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa
- Organizer
  The 25th Annual Meeting of ISHR Japanese Section
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 天然成分クルクミンを用いた新規心不全治療2008
- Author(s)
  森本達也, 砂川陽一, 川村晃久, 高谷智英, 和田啓道, 米田正始, 藤田正俊, 島津章, 北徹, 長谷川浩二
- Organizer
  第2回京都循環器フロンティアフォーラム
- Place of Presentation
  京都
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] プロテオミクスを用いた心筋細胞肥大に関与するGATA4結合因子の網羅的解析2008
- Author(s)
  森本達也, 砂川陽一, 高谷智英, 川村晃久, 和田啓道, 島津章, 藤田正俊, 北徹, 長谷川浩二
- Organizer
  第12回 Molecular Cardiovascular Conference
- Place of Presentation
  キロロ
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 喫煙が酸化LDLの血清レベルに及ぼす影響2008
- Author(s)
  和田啓道, 佐藤哲子, 北岡修二, 寺嶋幸子, 森本達也, 藤田正俊, 島津章, 高橋裕子, 長谷川浩二
- Organizer
  第3回禁煙科学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 可溶性VEGF受容体2のメタボリックシンドローム患者血清における上昇と心筋梗塞後の心機能に及ぼす影響2008
- Author(s)
  和田啓道, 佐藤哲子, 森本達也, 高谷智英, 中野為夫, 藤田正俊, 島津章, 長谷川浩二
- Organizer
  第45回日本臨床分子医学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Cardiac-specific transcription in ES cells by Cdk92008
- Author(s)
  S Kaichi, T Takaya, T Morimoto, Y Sunagawa, T Kawamura, K Ono, T Kita, T Heike, T Nakahata, K Hasegawa
- Organizer
  The 25th Annual Meeting of ISHR Japanese Section
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] A novel heart failure therapy that targets nuclear signaling pathway in cardiaomyocytes2008
- Author(s)
  Tatsuya Morimoto. Yoichi Sunagawa, Koji Hasegawa
- Organizer
  The 25th Annual Meeting of ISHR Japanese Section
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Curcumin, a Natural p300-specific Histone Acetyltransferase Inhibitor, Prevents the Development of Cardiac Hypertrophy in Rats2008
- Author(s)
  Tatsuya Morimoto, Masatoshi Fujita, Yoichi Sunagawa, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Akira Shimatsu, Tom Kita, Koji Hasegawa
- Organizer
  European Society of Cardiology Congress
- Place of Presentation
  Munich, Germany
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Cyclin-dependent Kinase-9 Is Required for Histone Acetyltransferase Activity of p3002008
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Toru Kita, Koji Hasegawa
- Organizer
  第72回日本循環器学会
- Place of Presentation
  博多、福岡
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Left ventricular expression of LOX-1 is markedly increased in proportion to the extent of hypertension-induced heart failure in rats2008
- Author(s)
  Takaya T, Morimoto T. Sunagawa Y, Wada H, Kawamura T, Shimatsu A, Fujita M, Fujita Y, Sawamura T, Hasegawa K
- Organizer
  第12回日本心不全学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] MicroRNA-1の過剰発現はマウスES細胞の心筋分化を抑制する2008
- Author(s)
  高谷智英, 川村晃久, 尾野亘, 高鍋利依子, 鵜内伸二, 馬場志郎, 平家俊男, 中畑龍俊, 森本達也, 北徹, 島津章, 長谷川浩二
- Organizer
  第45回日本臨床分子医学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 天然成分クルクミンを用いた新規心不全治療2008
- Author(s)
  森本達也
- Organizer
  平成19年度臨床心血管再生研究会
- Place of Presentation
  京都
- Year and Date
  2008-01-31
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Cyclin dependent kinase-9 is required for histoneacetyltransferase activity of p300 during cardiomyocyte hypertrophy2008
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Tomohide Takaya, Masatoshi Fujita, Toru Kita, Koji Hasegawa
- Organizer
  The 4th China-Japan Cardiovascular Forum(CJCF)
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Granulocyte-colony stimulating factor and erythropoietin synergistically improve left ventricular systolic function in heart failure after myocardial infarction in rats2008
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Tomoaki Kuwaki, Shigeki Yanagi, Akihiro Sugimoto, Masaki Tsukashita, Akira Mami, Tadashi Ikeda, Akira Shimatsu, Masatoshi Fujita, Tom Kita, Koji Hasegawa
- Organizer
  The 81^<th> American Heart Association Annual Scientific Sessions
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 梗塞後心不全に対するG-CSF/エリスロポイエチン組合せ療法2008
- Author(s)
  砂川陽一, 森本達也, 長谷川浩二
- Organizer
  平成19年度臨床心血管再生研究会
- Place of Presentation
  京都
- Year and Date
  2008-01-31
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Overexpression of microRNA-1 in mouse embryonic stem cells represses myocardial differentiation2008
- Author(s)
  Takaya T, Kawamura T, Ono K, Takanabe R, Kaichi S, Kita T, Wada H. Morimoto T. Shimatsu A, Hasegawa K
- Organizer
  第72回日本循環器学会
- Place of Presentation
  博多、福岡
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] p300/GATA4複合体の新規構成因子であるCDK9はES細胞から心筋への初期分化に重要な役割を果たす2008
- Author(s)
  鶏内伸二, 高谷智英, 森本達也, 砂川陽一, 川村晃久, 尾野亘, 北徹, 日高京子, 森崎隆幸, 馬場志郎, 平家俊男, 中畑龍俊, 長谷川浩二
- Organizer
  第8回心血管再生先端治療フォーラム
- Place of Presentation
  東京
- Year and Date
  2008-07-05
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Cdk9はp300のリン酸化やGATA4のアセチル化を充進し、心筋細胞肥大反応に必要である2008
- Author(s)
  砂川陽一, 森本達也, 高谷智英, 川村晃久, 和田啓道, 島津章, 藤田正俊, 北徹, 長谷川浩二
- Organizer
  第12回 Molecular Cardiovascular Conference
- Place of Presentation
  キロロ
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Curcumin, a Natural p300-specific Histone Acetyltransferase Inhibitor, Prevents the Development of Heart Failure in Rats2007
- Author(s)
  Tatsuya Morimoto
- Organizer
  The 80th American Heart Association Annual Scientific Sessions
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 天然物ウコン成分クルクミンによる心筋細胞核内アセチル化抑制を介した心不全治療2007
- Author(s)
  森本達也
- Organizer
  第11回 Molecular Cardiovascular Conference
- Place of Presentation
  キロロ
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] P-TEFb is a novel component of p300/GATA-4 complex required for hypertrophic responses in cardiac myocytes2007
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Tomohide Takaya, Masatoshi Fujita, Toru Kita, Koji Hasegawa
- Organizer
  The 3nd China-Japan Cardiovascular Forum(CJCF)
- Place of Presentation
  Beijing, China
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 天然成分クルクミンによる心筋細胞核内悄報伝違を標的とした心不全治療2007
- Author(s)
  森本達也
- Organizer
  第4回循環器フロンティア研究会
- Place of Presentation
  京都
- Year and Date
  2007-04-17
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] プロテオミクスにより同定した新規GATA4結合因子であるPositive Transcription Elongation Factor bは心筋細胞肥大反応に必要である2007
- Author(s)
  砂川陽一, 森本達也, 川村晃久, 高谷智英, 和田啓道, 島津章, 藤田正俊, 北徹, 長谷川浩二
- Organizer
  第11回Molecular Cardiovascular Conference
- Place of Presentation
  キロロ
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] CDK9 is a novel component of p300/GATA-4 complex required for hypertrophic responses in cardiac myocytes2007
- Author(s)
  Tatsuya Morimoto, Yoichi Sunagawa, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Toru Kita, Koji Hasegawa
- Organizer
  第11回日本心不全学会学術集会
- Place of Presentation
  浦安
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 心筋特異的p300/GATA4コンプレックスに含まれるCdk9は心筋細胞肥大反応に必要である2007
- Author(s)
  砂川陽一, 森本達也, 川村晃久, 高谷智英, 和田啓道, 島津章, 藤田正俊, 北徹, 長谷川浩二
- Organizer
  第11回日本適応医学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Cyclin-dependent Kinase-9はp300のHistone Acetyltransferase活性に必須である2007
- Author(s)
  砂川陽一, 森本達也, 川村晃久, 高谷智英, 和田啓道, 藤田正俊, 島津章, 北徹, 長谷川浩二
- Organizer
  第17回日本循環薬理学会
- Place of Presentation
  大阪
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Proteomics Analysis Identifies Positive Transcription Elongation Factor b as a Novel GATA-4-binding Partner Involved in Hypertrophic Responses in Cardiomyocytes2007
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Toru Kita, Koji Hasegawa
- Organizer
  The 80^<th> American Heart Association Annual Scientific Sessions
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] A Natural p300-specific Acetyltransferase Inhibitor, Prevents the Development of Heart Failure in vivo2007
- Author(s)
  Tatsuya Morimoto
- Organizer
  The 24th Annual Meeting of ISHR Japanese Section
- Place of Presentation
  Ferrara, Ialia
- Year and Date
  2007-06-21
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Crucumin, A Natural p300-specific Histone Acetyltransferase Inhibitor, Prevents the Development of Heart Failure in vivo2007
- Author(s)
  Tatsuya Morimoto, Yoichi Sunagawa, Tomohide Takaya, Koji Hasegawa, Masatoshi Fujita, Tom Kita
- Organizer
  The 24th Annual Meeting of ISHR Japanese Section
- Place of Presentation
  Ferrara, lalia
- Year and Date
  2007-06-21
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] A Natural p300-specific Histone Acetyltransferase Inhibitor, curcumin, Prevents the Development Heart Failure in rats2007
- Author(s)
  Tatsuya Morimoto, Yoichi Sunagawa, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Shoichi Miyamoto, Atsushi Nagasawa, Masashi Komeda, 2Masatoshi Fujita, Akira Shimatsu, Toru Kita, Koji
- Organizer
  The 14^<th> International Congress on Cardiovascular Pharmacotherapy
- Place of Presentation
  Antalya Turkey
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 天然物ウコン成分クルクミンによる心筋細胞核内アセチル化抑制を介した心不全治療2007
- Author(s)
  森本達也, 砂川陽一, 川村晃久, 高谷智英, 和田啓道, 宮本昌一, 長澤淳, 米田正始, 島津章, 藤田正俊, 北徹, 長谷川浩二
- Organizer
  第11回Molecular Cardiovascular Conference
- Place of Presentation
  キロロ
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 天然物成分クルクミンによる核内アセチル化をターゲットとした新規心不全治療の可能性2007
- Author(s)
  森本達也, 砂川陽一, 川村晃久, 高谷智英, 和田啓道, 米田正始, 藤田正俊, 島津章, 北徹, 長谷川浩二
- Organizer
  第17回日本循環薬理学会
- Place of Presentation
  大阪
- Year and Date
  2007-11-30
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 心筋細胞核内アセチル化抑制による新しい心不全治療薬の検討2007
- Author(s)
  砂川陽一, 森本達也, 高谷智英, 和田啓道, 宮本昌一, 川村晃久, 長澤淳, 米田正始, 藤田正俊, 島津章, 北徹, 長谷川浩二
- Organizer
  第44回日本臨床分子医学会
- Place of Presentation
  和歌山
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] Curcumin, a Natural p300-specific Histone Acetyltransferase Inhibitor, Prevents the Development of Heart Failure in Rats2007
- Author(s)
  Tatsuya Morimoto, Yoichi Sunagawa, Teruhisa Kawamura, Tomohide Takaya, Hiromichi Wada, Shoichi Miyamoto, Atsushi Nagasawa, Masashi Komeda, Masatoshi Fujita, Akira Shimatsu, Toru Kita, Koji Hasegawa
- Organizer
  The 80^<th> American Heart Association Annual Scientific Sessions
- Place of Presentation
  Orlando, USA
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] A Natural p300-specific Histone Acetyltransferase Inhibitor, Crucumin, Prevents the Development of Heart Failure in vivo2007
- Author(s)
  Yoichi Sunagawa, Tatsuya Morimoto, Teruhisa Kawamura, Tomohide Takaya, Shoichi Miyamoto, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Toru Kita, Koji Hasegawa
- Organizer
  第11回日本心不全学会学術集会
- Place of Presentation
  浦安
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] 心筋細胞核をターゲットとした新しい心不全治療の可能性2007
- Author(s)
  森本達也
- Organizer
  第11回日本適応医学会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19590842
[Presentation] PRMT5のメチル化活性がもたらす心肥大反応遺伝子転写抑制への影響
- Author(s)
  若林弘樹、中田淳也、刀坂泰史、北條祐也、砂川陽一、鈴木秀敏、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] 新規GATA4結合タンパク質MEP50による心肥大転写反応調節機構
- Author(s)
  宮﨑雄輔、刀坂泰史、櫻井涼賀、砂川陽一、鈴木秀敏、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本薬学会第135年会
- Place of Presentation
  兵庫
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] Receptor for Activated Protein Kinase C1 Suppresses Hypertrophic Responses by Inhibition of the Association between p300 and GATA4
- Author(s)
  Hidetoshi Suzuki, Yoichi Sunagawa, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  International Society of Cardiovascular Phamacotherapy 2014
- Place of Presentation
  Adelaide,Australia
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-26460071
[Presentation] MEK-1-dependent Phosphorylation of GATA4 Attenuates the Repressor Function of Novel GATA4 Binding Proteins, RbAp48/46, during Cardiomyocyte Hypertrophy
- Author(s)
  Yoichi Sunagawa, Yasufumi Katanasaka, Hidetoshi Suzuki, Naruto Hajika, Hiromichi Wada, Akira Shimatsu, Masatoshi Fujita, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第18回国際心血管生物学会
- Place of Presentation
  京都
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-26460071

1. 砂川陽一 (30466297)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
2. KITA Toru (60161460)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. 浜辺俊秀 (90963314)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SHIOI Tetsuo (50360095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HASEGAWA Koji (50283594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. ONO Koh (00359275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. Kurokawa Junko (40396982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 宮崎雄輔 (40803466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
9. MURAYAMA Toshinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 横出正之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Morimoto Tatuya 森本 達也

Morimoto Tatsuya 森本 達也

MORIMOTO Tatsuya 森本 達也

Research Projects

Research Products

Co-Researchers

The studyon of p300 complex on cardiac hypertrophy and fibrosis during the development of heart failure

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ノックインマウスを用いた心不全によるGATA4多量体形成の変化並びに治療薬の探索研究Principal Investigator

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Identification and functional analysis of p300 regulatory factors involved in the development of heart failure using medical proteomicsPrincipal Investigator

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Roles of sex chromosomes in pathophysiological sex difference formation in the heart

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Investigation of novel heart failure therapy targeting transcription complexPrincipal Investigator

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Identifying the novel therapeutic targets by investigating the regulatory mechanism of transcription complex during the development of heart failurePrincipal Investigator

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Analysis of activation mechanism of cardiac p300/GATA4 pathway during heart failurePrincipal Investigator

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Purification and analysis of a transoription factor, GATA4 complex from adult mouse heart during developing heart failurePrincipal Investigator

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Analysis of cardiac specific transcription factor GATA-4 complex during differentiation of mouse embryonic stem cells into cardiac myocytesPrincipal Investigator

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Identification of intracellular signaling molecules that bind to cardiac p300 during the development of heart failure and its application to pharmacological therapy

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[Book] 転写因子のアセチル化と心臓リモデリング 細胞工学Vol. 26 No 42007

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[Journal Article] Cardiomyocyte Sirt (Sirtuin) 7 Ameliorates Stress-Induced Cardiac Hypertrophy by Interacting With and Deacetylating GATA42020

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[Journal Article] The Synthetic Curcumin Analogue GO-Y030 Effectively Suppresses the Development of Pressure Overload-induced Heart Failure in Mice.2020

Author(s)

Journal Title

Morimoto Tatuya 森本達也

Morimoto Tatsuya 森本達也

MORIMOTO Tatsuya 森本達也

[Book] 転写因子のアセチル化と心臓リモデリング細胞工学Vol. 26 No 42007

[Journal Article] α1-Antitrypsin Low-Density-Lipoprotein Serves as a Marker of Smoking-Specific Oxidative Stress2012