NAKAHATA Yasukazu 中畑泰和

… Alternative Names

中畑泰和ナカハタヤスカズ

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Researcher Number	50390810
Other IDs
Affiliation (Current)	2025: 長崎大学, 医歯薬学総合研究科(医学系), 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 長崎大学, 医歯薬学総合研究科(医学系), 准教授 2019 – 2020: 長崎大学, 医歯薬学総合研究科(医学系), 准教授 2018: 奈良先端科学技術大学院大学, 先端科学技術研究科, 助教 2010 – 2017: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 2011: 奈良先端科学技術大学院大学, バイサイエンス研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Environmental physiology(including physical medicine and nutritional physiology) / Tumor biology / General anatomy (including Histology/Embryology) / Environmental physiology (including Physical medicine and Nutritional physiology) / Biological Sciences / Functional biochemistry Except Principal Investigator System genome science / Basic Section 44020:Developmental biology-related / Developmental biology
Keywords	Principal Investigator 細胞老化 / 概日時計 / NAD+ / NAD+代謝 / NAD代謝 / 代謝 / 老化 / NAMPT / SIRT1 / Nampt … More / 体節形成 / 先天異常学・奇形学 / 代謝性疾患 / ライブイメージング / エネルギー代謝 / NAD^+ / FRET / ケミカルバイオロジー / 生体エネルギー変換 … More Except Principal Investigator 体節 / 遺伝子発現 / マウス / Notch / 体節形成 / ロバスト性 / 形態形成 / 発生 / 神経 / 細胞の社会性 / 細胞の集団行動 / 有毛細胞 / ゼブラフィッシュ / クッペル胞 / 側線器官 / 器官サイズ / シグナル伝達 / 発現制御 / 発生・分化 / ジーンドセージ / 遺伝子 / Notchシグナル / ノックインマウス / Notchシグナリング / 濃度勾配 / FGF / 時間制御 / 転写因子 / 分節化 / 生物時計 / Notch シグナル / 振動 Less

NAD+による概日リズム回復と老化抑制の関連性解明Principal Investigator
- Principal Investigator
  
  中畑泰和
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
- Research Institution
  Nagasaki University
The mechanism of organ-size determination via social behavior of their progenitor cells in animal development
- Principal Investigator
  
  Bessho Yasumasa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Nara Institute of Science and Technology
Effects of circadian clock and NAD+ metabolism on cellular scenesencePrincipal Investigator
- Principal Investigator
  
  NAKAHATA Yasukazu
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Nagasaki University
  Nara Institute of Science and Technology
The system for fine tuning of signal transduction that maintains the robustness in morphogenesis
- Principal Investigator
  
  Bessho Yasumasa
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  Nara Institute of Science and Technology
Effects of NAD+ metabolism on cellular senescence/tumorigenesisPrincipal Investigator
- Principal Investigator
  
  NAKAHATA Yasukazu
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Nara Institute of Science and Technology
Alteration of the level of Notch signaling activity in mouse embryo by gene duplication of Notch
- Principal Investigator
  
  BESSHO Yasumasa
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  System genome science
- Research Institution
  Nara Institute of Science and Technology
Effects of SIRT1 activation on TeratogenesisPrincipal Investigator
- Principal Investigator
  
  NAKAHATA Yasukazu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Nara Institute of Science and Technology
概日ＮＡＤ＋代謝制御の破綻による肥満発症メカニズムの解明Principal Investigator
- Principal Investigator
  
  中畑泰和
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
Effects of Circadian NAD+ oscillation on the onset of age-related diseasesPrincipal Investigator
- Principal Investigator
  
  NAKAHATA Yasukazu
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Environmental physiology (including Physical medicine and Nutritional physiology)
- Research Institution
  Nara Institute of Science and Technology
The mechanism of the molecular clock that controls developmental dynamics
- Principal Investigator
  
  BESSHO Yasumasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  System genome science
- Research Institution
  Nara Institute of Science and Technology
Develop an intracellular NAD+live-imaging technologyPrincipal Investigator
- Principal Investigator
  
  NAKAHATA Yasukazu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  Nara Institute of Science and Technology

[Book] Sleep and Clocks in Aging and Longevity　（Chapter 5: Impact of Cellular Senescence on Cellular Clocks）2023
- Author(s)
  Editor Anita Jagota (Chapter 5: Yasukazu Nakahata)
- Total Pages
  561
- Publisher
  Springer Cham
- ISBN
  9783031224676
- Data Source
  KAKENHI-PROJECT-22K06320
[Journal Article] Comparative analysis of chronological and biological aging on the potential of in vitro cultured human adipose-derived mesenchymal stem cells2024
- Author(s)
  Harunori Oda, Eiko Omichi, Eri Oda, Ryosuke Shinohara, Hiroko Oda, Shinya Aoyama, Wataru Tarumi, Xia Ling, Kazuyuki Shinohara, Yasukazu Nakahata
- Journal Title
  
  Acta medica Nagasakiensia
  
  Volume: 67 Pages: 40-60
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06320
[Journal Article] Cellular senescence and its impact on the circadian clock2022
- Author(s)
  Ahmed Rezwana、Reza Hasan Mahmud、Shinohara Kazuyuki、Nakahata Yasukazu
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 171 Issue: 5 Pages: 493-500
- DOI
  10.1093/jb/mvab115
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06320
[Journal Article] Human placental extract activates a wide array of gene expressions related to skin functions2022
- Author(s)
  Chang Phooi-Yee、Chin Lit-Chein、Kimura Koichi、Nakahata Yasukazu
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1
- DOI
  10.1038/s41598-022-15270-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06320
[Journal Article] Molecular connections between circadian clock and health/ageing2022
- Author(s)
  Nakahata Yasukazu、Fukada Yoshitaka
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 171 Issue: 5 Pages: 473-476
- DOI
  10.1093/jb/mvac028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06320
[Journal Article] Human Placental Extract Delays In Vitro Cellular Senescence through the Activation of NRF2-Mediated Antioxidant Pathway2022
- Author(s)
  Huang Liguo、Chin Lit-Chein、Kimura Koichi、Nakahata Yasukazu
- Journal Title
  
  Antioxidants
  
  Volume: 11 Issue: 8 Pages: 1545-1545
- DOI
  10.3390/antiox11081545
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06320
[Journal Article] Chrono-Nutrition Has Potential in Preventing Age-Related Muscle Loss and Dysfunction2021
- Author(s)
  Aoyama Shinya、Nakahata Yasukazu、Shinohara Kazuyuki
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 15 Pages: 1-7
- DOI
  10.3389/fnins.2021.659883
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08569, KAKENHI-PROJECT-20K19710
[Journal Article] Attenuated SIRT1 activity leads to PER2 cytoplasmic localization and dampens the amplitude of Bmal1 promoter-driven circadian oscillation2021
- Author(s)
  Ashimori Atsushige、Nakahata Yasukazu、Sato Toshiya、Fukamizu Yuichiro、Matsui Takaaki、Shinohara Kazuyuki、Bessho Yasumasa
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: - Pages: 647589-647589
- DOI
  10.3389/fnins.2021.647589
- NAID
  120007168842
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08569, KAKENHI-PROJECT-20K18384, KAKENHI-PROJECT-17H06096, KAKENHI-PROJECT-19H03175, KAKENHI-PROJECT-21K18231, KAKENHI-PROJECT-19K22433
[Journal Article] Nicotinamide Phosphoribosyltransferase as a Key Molecule of the Aging/Senescence Process2021
- Author(s)
  Khaidizar Fiqri D.、Bessho Yasumasa、Nakahata Yasukazu
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 7 Pages: 3709-3709
- DOI
  10.3390/ijms22073709
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08569, KAKENHI-PROJECT-19K22433
[Journal Article] Cellular Senescence Triggers Altered Circadian Clocks With a Prolonged Period and Delayed Phases2021
- Author(s)
  Ahmed Rezwana、Nakahata Yasukazu、Shinohara Kazuyuki、Bessho Yasumasa
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 15 Pages: 638122-638122
- DOI
  10.3389/fnins.2021.638122
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22433, KAKENHI-PROJECT-17K08569
[Journal Article] Over‐expression of Nicotinamide phosphoribosyltransferase in mouse cells confers protective effect against oxidative and ER stress‐induced premature senescence2020
- Author(s)
  Nuriliani Ardaning、Nakahata Yasukazu、Ahmed Rezwana、Khaidizar Fiqri D.、Matsui Takaaki、Bessho Yasumasa
- Journal Title
  
  Genes to Cells
  
  Volume: 25 Issue: 8 Pages: 593-602
- DOI
  10.1111/gtc.12794
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22433, KAKENHI-PROJECT-17K08569
[Journal Article] Replicative senescent human cells possess altered circadian clocks with a prolonged period and delayed peak-time2019
- Author(s)
  Rezwana Ahmed, Atsushige Ashimori, Satoshi Iwamoto, Takaaki Matsui, Yasukazu Nakahata, and Yasumasa Bessho
- Journal Title
  
  Aging (Albany NY)
  
  Volume: 11 Issue: 3 Pages: 950-973
- DOI
  10.18632/aging.101794
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08569, KAKENHI-PROJECT-16K15220, KAKENHI-PUBLICLY-17H05768, KAKENHI-PROJECT-18H02451
[Journal Article] Presomitic mesoderm-specific expression of the transcriptional repressorHes7is controlled by E-box, T-box, and Notch signaling pathways2018
- Author(s)
  Hayashi Shinichi、Nakahata Yasukazu、Kohno Kenji、Matsui Takaaki、Bessho Yasumasa
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 31 Pages: 12167-12176
- DOI
  10.1074/jbc.ra118.003728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15220, KAKENHI-PUBLICLY-17H05768, KAKENHI-PROJECT-18H02451
[Journal Article] Bmal1-deficient mouse fibroblast cells do not provide premature cellular senescence in vitro2018
- Author(s)
  Nakahata Yasukazu、Yasukawa Shiori、Khaidizar Fiqri Dizar、Shimba Shigeki、Matsui Takaaki、Bessho Yasumasa
- Journal Title
  
  Chronobiology International
  
  Volume: 印刷中 Issue: 5 Pages: 1-9
- DOI
  10.1080/07420528.2018.1430038
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08569, KAKENHI-PROJECT-16K15220, KAKENHI-PROJECT-17K08291
[Journal Article] Nicotinamide phosphoribosyltransferase delays cellular senescence by upregulating SIRT1 activity and antioxidant gene expression in mouse cells2017
- Author(s)
  Khaidizar Fiqri D.、Nakahata Yasukazu、Kume Akira、Sumizawa Kyosuke、Kohno Kenji、Matsui Takaaki、Bessho Yasumasa
- Journal Title
  
  Genes to Cells
  
  Volume: 22 Issue: 12 Pages: 982-992
- DOI
  10.1111/gtc.12542
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08569, KAKENHI-PROJECT-16K15220, KAKENHI-PLANNED-26116006
[Journal Article] The circadian NAD+ metabolism: Impact on chromatin remodeling and aging.2016
- Author(s)
  Nakahata Y, Bessho Y
- Journal Title
  
  BioMed Research International
  
  Volume: 2016 Pages: 3208429-3208429
- DOI
  10.1155/2016/3208429
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01355, KAKENHI-PROJECT-26291050, KAKENHI-PROJECT-16K15220
[Journal Article] CRY drives cyclic CK2-mediated BMAL1 phosphorylation to control the mammalian circadian clock2015
- Author(s)
  1)Tamaru T, Hattori M, Honda K, Nakahata Y, Sassone-Corsi P, van der Horst GTJ, Ozawa T, Takamatsu K
- Journal Title
  
  PLoS Biology
  
  Volume: 13 Issue: 11 Pages: e1002293-e1002293
- DOI
  10.1371/journal.pbio.1002293
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08217, KAKENHI-PROJECT-15H05488, KAKENHI-PROJECT-26670024, KAKENHI-PROJECT-26830074, KAKENHI-PROJECT-26220805
[Journal Article] miR-199a links MeCP2 with mTOR signaling and its dysregulation leads to Rett Syndrome phenotypes.2015
- Author(s)
  Tsujimura K, Irie K, Nakashima H, Egashira Y, Fukao Y, Fujiwara M, Itoh M, Uesaka M, Imamura T, Nakahata Y, Yamashita Y, Abe T, Takamori S, Nakashima K.
- Journal Title
  
  Cell Rep
  
  Volume: 12 Issue: 11 Pages: 1887-1901
- DOI
  10.1016/j.celrep.2015.08.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26115716, KAKENHI-PROJECT-24240051, KAKENHI-PROJECT-15J06414, KAKENHI-PROJECT-26830074, KAKENHI-PROJECT-24390270
[Journal Article] Hes7 3’UTR is required for somite segmentation function2014
- Author(s)
  Takeshi Fujimuro, Takaaki Matsui, Yasuhide Nitanda, Tatsuro Matta, Yuichi Sakumura, Michiko Saito, Kenji Kohno, Yasukazu Nakahata and Yasumasa Bessho
- Journal Title
  
  Scientific Reports
  
  Volume: 4 Issue: 1 Pages: 6462-6462
- DOI
  10.1038/srep06462
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-25111718, KAKENHI-PUBLICLY-25127711, KAKENHI-PROJECT-26291050, KAKENHI-PROJECT-24228002
[Journal Article] 3’UTR-dependent regulation of mRNA turnover is critical for differential distribution patterns of cyclic gene mRNAs.2014
- Author(s)
  Nitanda et al.
- Journal Title
  
  FEBS J
  
  Volume: 281 Issue: 1 Pages: 146-156
- DOI
  10.1111/febs.12582
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24651230, KAKENHI-PROJECT-24659086, KAKENHI-PUBLICLY-25111718, KAKENHI-PUBLICLY-25127711, KAKENHI-PROJECT-24681043
[Journal Article] Sassone-Corsi P.Pharmacological modulation of circadian rhythms by synthetic activators of the deacetylase SIRT12013
- Author(s)
  Bellet MM, Nakahata Y, Boudjelal M,Watts E, Mossakowska DE, Edwards KA,Cervantes M, Astarita G, Loh C, Ellis JL,Vlasuk GP
- Journal Title
  
  Proc. Natl. Acad. Sci.USA
  
  Volume: 110 Issue: 9 Pages: 3333-3338
- DOI
  10.1073/pnas.1214266110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22310126, KAKENHI-PROJECT-23689013
[Journal Article] 概日NAD+/SIRT1活性による老化進行および老化関連疾患発症の可能性2011
- Author(s)
  中畑泰和
- Journal Title
  
  時間生物学(日本時間生物学会学会誌)
  
  Volume: Vol.17No.2 Pages: 69-74
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23126515
[Journal Article] NAD^+/SIRT1が結ぶ体内時計と老化・代謝2011
- Author(s)
  中畑泰和
- Journal Title
  
  心臓
  
  Volume: Vol.43 No.2 Pages: 140-144
- Data Source
  KAKENHI-PROJECT-22657035
[Presentation] ヒト胎盤抽出液の効果に関する基礎研究 ~皮膚細胞への影響~2023
- Author(s)
  中畑泰和
- Organizer
  第31回日本プラセンタ医学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06320
[Presentation] Human placental extract activates a wide array of gene expressions related to skin functions2022
- Author(s)
  中畑泰和, Chang Phooi-Yee, Chin Lit-Chein, 木村孝一
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-22K06320
[Presentation] NAMPT-mediated disruption of intestinal integrity by leading malignant transformation of intestinal epithelial stem2022
- Author(s)
  中津秀介，李卓青，真島剛史，魏杉，中畑泰和，山本穂高，松井貴輝，廣田俊，別所康全，金井賢一
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-22K06320
[Presentation] NAD+生合成系酵素NAMPTによる腸上皮幹細胞の悪性化と腸バリア機能破綻の分子機構の解析2022
- Author(s)
  中津秀介, 李卓青, 真島剛史, 魏杉, 中畑泰和, 山本穂高, 松井貴輝, 廣田俊, 別所康全, 金井賢一
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18H02451
[Presentation] 概日時計と NAD+代謝による相互制御とその破綻による老化2022
- Author(s)
  中畑泰和
- Organizer
  日本農芸化学会中部支部第 193 回例会
- Invited
- Data Source
  KAKENHI-PROJECT-22K06320
[Presentation] Replicative senescent human cells possess altered circadian clocks with a prolonged period and delayed peak-time2020
- Author(s)
  Yasukazu Nakahata, Rezwana Ahmed, Atsushige Ashimori, Kazuyuki Shinohara, Yasumasa Bessho
- Organizer
  第97会日本生理学会大会
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] Cellular senescence alters the circadian clock via intracellular NAD+2019
- Author(s)
  Yasukazu Nakahata
- Organizer
  13th Malaysia International Genetics Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] Implantable microimaging CMOS sensor for deep brain gene expression analysis in freely behaving mice2019
- Author(s)
  J.Olorocisimo, J.Briones, R.Rebusi, Y.Ohta, M.Haruta, K.Sasagawa, Y.Nakahata, Y.Bessho, J.Ohta
- Organizer
  Neuroscience2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02451
[Presentation] Replicative senescent human cells possess altered circadian clocks with a prolonged period and delayed peak-time2019
- Author(s)
  Rezwana Ahmed, Satoshi Iwamoto, Yasukazu Nakahata, Takaaki Matsui, Yasumasa Bessho
- Organizer
  XVI EUROPEAN BIOLOGICAL RHYTHMS SOCIETY CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] Circadian Period extension due to impairment of NAD+/PARP12018
- Author(s)
  Atsushige Ashimori, Yasukazu Nakahata, Takaaki Matsui, Yasumasa Bessho
- Organizer
  International Symposium on Biological Rhythms (JSC国際シンポジウム)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02451
[Presentation] Changes in Circadian Clock Properties of Replicative Senescent TIG-3 cells2018
- Author(s)
  Rezwana Ahmed, 岩本賢, 中畑泰和, 松井貴輝, 別所康全
- Organizer
  第２５回日本時間生物学会学術大会
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] Circadian Period extension due to impairment of NAD+/PARP1経路の機能低下による概日時計周期延長2018
- Author(s)
  芦森温茂, 中畑泰和, 松井貴輝, 別所康全
- Organizer
  第２５回日本時間生物学会学術大会
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] Decrease in NAD+ causes period extension of circadian clock with aging2018
- Author(s)
  A. Ashimori, R. Ahmed, Y. Nakahata, S. Iwamoto, T. Matsui and Y. Bessho
- Organizer
  Cell Symposia: Aging and Metabolism 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] Intracellular NAD+ regulates the period of circadian clock2017
- Author(s)
  Yasukazu Nakahata
- Organizer
  Internatioal Conference on Genomics, Nanotech and Bioengineerling 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] NAD+減少に起因する概日時計周期延長の分子機構の解明2017
- Author(s)
  芦森温茂, 中畑　泰和, 松井貴輝, 別所　康全
- Organizer
  第24回日本時間生物学会
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] NAMPT overexpression delays cellular senescence by upregulating superoxide dismutase 2 and catalase gene expressions in mouse cells2017
- Author(s)
  Yasukazu Nakahata, Fiqri Dizar Khaidizar, Takaaki Matsui and Yasumasa Bessho
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] THE IMPACT OF CELLULAR SENESCENCE ON CIRCADIAN CLOCK2017
- Author(s)
  Rezwana Ahmed, Satoshi Iwamoto, Yasukazu Nakahata, Takaaki Matsui, Yasumasa Bessho
- Organizer
  Internatioal Conference on Genomics, Nanotech and Bioengineerling 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] The Impact of Cellular Senescence on Circadian Clock2017
- Author(s)
  Yasukazu Nakahata
- Organizer
  BIT's 5th Annual World Congress of Geriatrics and Gerontology-2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] 概日時計はin vitroでの細胞老化進行に関与しない2017
- Author(s)
  中畑　泰和, 安川史織, 榛葉繁紀, 松井貴輝, 別所　康全
- Organizer
  第24回日本時間生物学会学術大会
- Data Source
  KAKENHI-PROJECT-17K08569
[Presentation] The Impact of Decrease in NAD+ with Cellular Senscence on the Period of Circadian Gene Expression2016
- Author(s)
  Iwamoto S, Nakahata Y, Ashimori A, Matsui T, Bessho Y
- Organizer
  第23回日本時間生物学会学術大会
- Place of Presentation
  名古屋大学豊田講堂、愛知県名古屋市
- Year and Date
  2016-11-12
- Data Source
  KAKENHI-PROJECT-26291050
[Presentation] 細胞内NAD+による概日時計遺伝子発現変動の制御2016
- Author(s)
  中畑泰和、別所康全
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター(北海道札幌市)
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-26291050
[Presentation] Molecular Mechanism to Lengthen the Circadian Period by Low NAD+2016
- Author(s)
  Ashimori A, Nakahata Y, Matsui T, Bessho Y
- Organizer
  International Symposium on Biological Thythms
- Place of Presentation
  名古屋大学豊田講堂、愛知県名古屋市
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-26291050
[Presentation] Molecular Mechanism to Lengthen the Circadian Period by Low NAD+2016
- Author(s)
  Ashimori A, Nakahata Y, Matsui T, Bessho Y
- Organizer
  第23回日本時間生物学会学術大会
- Place of Presentation
  名古屋大学豊田講堂、愛知県名古屋市
- Year and Date
  2016-11-12
- Data Source
  KAKENHI-PROJECT-26291050
[Presentation] The Impact of Decrease in NAD+ with Cellular Senscence on the Period of Circadian Gene ExpressionT2016
- Author(s)
  Iwamoto S, Nakahata Y, Ashimori A, Matsui T, Bessho Y
- Organizer
  International Symposium on Biological Thythms
- Place of Presentation
  名古屋大学豊田講堂、愛知県名古屋市
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-26291050
[Presentation] 細胞内NAD+による概日時計遺伝子発現変動の制御2016
- Author(s)
  中畑泰和, 別所康全
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2016-03-22
- Invited
- Data Source
  KAKENHI-PROJECT-26830074
[Presentation] 概日時計～その破綻と疾病の関連性～2015
- Author(s)
  中畑泰和
- Organizer
  2014年度研究大学シンポジウム「地域創生のための、けいはんなにおける新たな産学官ネットワークの展開」
- Place of Presentation
  リーガロイヤルホテル京都 (京都府京都市)
- Year and Date
  2015-03-30
- Invited
- Data Source
  KAKENHI-PROJECT-23689013
[Presentation] Reduction of intracellular NAD+ promotes the extension of periods of circadian clock genes2015
- Author(s)
  Atsushige Ashimori, Yasukazu Nakahata, Takaaki Matsui and Yasumasa Bessho
- Organizer
  第22回時間生物学会学術大会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26830074
[Presentation] 概日時計機構および細胞老化におけるNAD+/NAMPTの影響2015
- Author(s)
  中畑泰和, 芦森温茂, 松井貴輝, 別所康全
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291050
[Presentation] NAD+の減少は、概日時計遺伝子発現周期の延長を惹起する2015
- Author(s)
  Atsushige Ashimori, Yasukazu Nakahata, Takaaki Matsui, Yasumasa Bessho
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26291050
[Presentation] 概日時計～その破綻と疾病の関連性～2015
- Author(s)
  中畑泰和
- Organizer
  2014年度研究大学シンポジウム「地域創生のための、けいはんなにおける新たな産学官ネットワークの展開」
- Place of Presentation
  リーガロイヤルホテル京都（京都府京都市）
- Year and Date
  2015-03-30
- Invited
- Data Source
  KAKENHI-PROJECT-26830074
[Presentation] CRY-driven circadian oscillation of mammalian clock protein kinase activity2015
- Author(s)
  田丸輝也, 服部満, 中畑泰和, 小澤岳昌, 高松研
- Organizer
  第22回時間生物学会学術大会
- Place of Presentation
  東京大学（東京都文京区）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26830074
[Presentation] Reduction of intracellular NAD+ promotes the extension of periods of circadian clock genes2015
- Author(s)
  Atsushige Ashimori, Yasukazu Nakahata, Takaaki Matsui, Yasumasa Bessho
- Organizer
  日本時間生物学会学術大会
- Place of Presentation
  東京大学本郷キャンパス伊藤国際学術研究センター(東京都文京区)
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26291050
[Presentation] NAD+の減少は、概日時計遺伝子発現周期の延長を惹起する2015
- Author(s)
  Atsushige Ashimori, Yasukazu Nakahata, Takaaki Matsui and Yasumasa Bessho
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26830074
[Presentation] 概日時計機構および細胞老化におけるNAD+/NAMPTの影響2015
- Author(s)
  中畑泰和, 芦森温茂, 松井貴輝, 別所康全
- Organizer
  BMB2015
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-26830074
[Presentation] A negative feedback loop of Nrarp provides robustness to the somite segmentation clock2014
- Author(s)
  Nitanda Y, Kim W, Matsui T, Nakahata Y, Sakumura Y, Bessho Y
- Organizer
  The 62nd NIBB Conference Force in Development
- Place of Presentation
  Okazaki, Japan
- Year and Date
  2014-11-17
- Data Source
  KAKENHI-PROJECT-26291050
[Presentation] NAD+ metabolism and NAD+-dependent protein deacetylase “Sirtuins” Regulations by Circadian Clock and Aging2014
- Author(s)
  中畑泰和
- Organizer
  Program of Molecular Clock 2014: Epigenetic Landscape in Biological Rhythms
- Place of Presentation
  京都大学 (京都府京都市)
- Year and Date
  2014-03-29
- Invited
- Data Source
  KAKENHI-PROJECT-23689013
[Presentation] 概日時計と分節時計を制御する脱アセチル化酵素SIRT12012
- Author(s)
  中畑泰和
- Organizer
  日本時間生物学術大会
- Place of Presentation
  北海道大学
- Year and Date
  2012-09-16
- Invited
- Data Source
  KAKENHI-PUBLICLY-23126515
[Presentation] 3'UTR依存的なmRNAの分解制御は発現振動遺伝子の発現領域の違いを生み出す2012
- Author(s)
  三反田康秀、松井貴輝、松田達郎、樋上絢、中畑泰和、別所康全
- Organizer
  日本分子生物学会
- Place of Presentation
  福岡市
- Year and Date
  2012-12-14
- Data Source
  KAKENHI-PROJECT-24659086
[Presentation] CLOCK-SIRT1による概日時計制御2010
- Author(s)
  中畑泰和
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  岩手
- Year and Date
  2010-05-19
- Data Source
  KAKENHI-PROJECT-22657035
[Presentation] NAD+代謝による概日時計制御機構2010
- Author(s)
  中畑泰和
- Organizer
  第17回日本時間生物学学術第会
- Place of Presentation
  東京
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-22657035
[Presentation] 3’UTR依存的なmRNAの分解制御は発現振動遺伝子の発現領域の違いを生み出す
- Author(s)
  二反田康秀、松井貴輝、松田達郎、樋上絢、中畑泰和、別所康全
- Organizer
  第３８回分子生物学会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-24659086
[Presentation] Circadian Rhythm Regulation by NAD+-dependent protein deacetylase “SIRT1”
- Author(s)
  中畑泰和
- Organizer
  1st International Symposium of Blue Light Society
- Place of Presentation
  JPタワー (東京都千代田区)
- Year and Date
  2013-06-06 – 2013-06-08
- Invited
- Data Source
  KAKENHI-PROJECT-23689013
[Presentation] クロノスDioを用いた新規アッセイ系の確立
- Author(s)
  中畑泰和
- Organizer
  第２回超異分野学会
- Place of Presentation
  東京都墨田区
- Data Source
  KAKENHI-PROJECT-24659086

1. BESSHO Yasumasa (70261253)

# of Collaborated Projects: 5 results

# of Collaborated Products: 30 results
2. SAKUMURA Yuichi (50324968)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. MATSUI Takaaki (60403333)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
4. 笹井紀明 (80391960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 樽見航 (40714895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 作村勇一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 田丸輝也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 服部満

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 高森茂雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKAHATA Yasukazu 中畑 泰和

中畑 泰和 ナカハタ ヤスカズ

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Co-Researchers

NAD+による概日リズム回復と老化抑制の関連性解明Principal Investigator

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The mechanism of organ-size determination via social behavior of their progenitor cells in animal development

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Effects of circadian clock and NAD+ metabolism on cellular scenesencePrincipal Investigator

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The system for fine tuning of signal transduction that maintains the robustness in morphogenesis

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Effects of NAD+ metabolism on cellular senescence/tumorigenesisPrincipal Investigator

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Alteration of the level of Notch signaling activity in mouse embryo by gene duplication of Notch

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Effects of SIRT1 activation on TeratogenesisPrincipal Investigator

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概日ＮＡＤ＋代謝制御の破綻による肥満発症メカニズムの解明Principal Investigator

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Effects of Circadian NAD+ oscillation on the onset of age-related diseasesPrincipal Investigator

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The mechanism of the molecular clock that controls developmental dynamics

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Develop an intracellular NAD+live-imaging technologyPrincipal Investigator

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[Book] Sleep and Clocks in Aging and Longevity （Chapter 5: Impact of Cellular Senescence on Cellular Clocks）2023

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[Journal Article] Comparative analysis of chronological and biological aging on the potential of in vitro cultured human adipose-derived mesenchymal stem cells2024

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NAKAHATA Yasukazu 中畑泰和

中畑泰和ナカハタヤスカズ

[Book] Sleep and Clocks in Aging and Longevity　（Chapter 5: Impact of Cellular Senescence on Cellular Clocks）2023