Ohta Hiroshi 大田浩

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OHTA Hiroshi 大田浩

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Researcher Number	50391892
Other IDs
Affiliation (Current)	2022: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2018 – 2022: 京都大学, 医学研究科, 准教授 2016 – 2018: 京都大学, 医学研究科, 助教 2013 – 2015: 京都大学, 医学(系)研究科(研究院), 助教 2012: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Laboratory animal science / Laboratory animal science / Integrative animal science / Basic Section 52050:Embryonic medicine and pediatrics-related / Medium-sized Section 48:Biomedical structure and function and related fields Except Principal Investigator Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
Keywords	Principal Investigator 始原生殖細胞 / ES細胞 / 卵子形成 / 培養 / 分化誘導 / 増殖 / 分化 / 細胞分化 / 試験管内 / 再構成卵巣 … More / 小分子化合物 / 増殖・分化 / 精子形成 / chemical libray / high-throughput screening / EpiLC / 配偶子形成 / 細胞培養 / 細胞増殖 / 卵母細胞 / 卵原細胞 / 始原生殖細胞様細胞 / 試験管内誘導 / ヒト / 多能性幹細胞 / 胎生期生殖巣 / iPS細胞 / in vitro / 生殖巣 / 体細胞 / 支持細胞 … More Except Principal Investigator 性決定 / 絶滅危惧種 / iPS細胞 / 生殖巣 / 生殖細胞 Less

Elucidation of the gene expression cascade responsible for male sexuality and acquisition of fertility
- Principal Investigator
  
  本多新
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Jichi Medical University
  Kyoto University
試験管内において卵子形成の支持が可能な卵巣体細胞の新規培養法の確立Principal Investigator
- Principal Investigator
  
  大田浩
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Kyoto University
Establishment of culture system for inducing oocytes from primordial germ cell-like cellsPrincipal Investigator
- Principal Investigator
  
  大田浩
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Kyoto University
Establishment of efficient induction system for primordial germ cells from ES cells in vitroPrincipal Investigator
- Principal Investigator
  
  Ohta Hiroshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University
Analysis of proliferation and differentiation of primordial germ cell-like cells derived from ES cellsPrincipal Investigator
- Principal Investigator
  
  Ohta Hiroshi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Integrative animal science
- Research Institution
  Kyoto University
Establishment of novel technique using primordial germ cells induced from embryonic stem cellsPrincipal Investigator
- Principal Investigator
  
  OHTA Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyoto University

All 2020 2018 2017 2013

All Journal Article Patent

[Journal Article] Cyclosporin A and FGF signaling support the proliferation/survival of mouse primordial germ cell-like cells in vitro2020
- Author(s)
  Ohta Hiroshi、Yabuta Yukihiro、Kurimoto Kazuki、Nakamura Tomonori、Murase Yusuke、Yamamoto Takuya、Saitou Mitinori
- Journal Title
  
  Biology of Reproduction
  
  Volume: 104 Pages: 344-360
- DOI
  10.1093/biolre/ioaa195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21500, KAKENHI-PLANNED-18H05553, KAKENHI-PROJECT-20H00471, KAKENHI-PROJECT-19H03618, KAKENHI-PROJECT-18K19295
[Journal Article] Long‐term expansion with germline potential of human primordial germ cell‐like cells in vitro2020
- Author(s)
  Murase Yusuke、Yabuta Yukihiro、Ohta Hiroshi、Yamashiro Chika、Nakamura Tomonori、Yamamoto Takuya、Saitou Mitinori
- Journal Title
  
  The EMBO Journal
  
  Volume: 39
- DOI
  10.15252/embj.2020104929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21500, KAKENHI-PROJECT-19H03618
[Journal Article] Induction of the germ cell fate from pluripotent stem cells in cynomolgus monkeys†2020
- Author(s)
  Sakai Y, Nakamura T, Okamoto I, Gyobu-Motani S, Ohta H, Yabuta Y, Tsukiyama T, Iwatani C, Tsuchiya H, Ema M, Morizane A, Takahashi J, Yamamoto T, Saitou M.
- Journal Title
  
  Biology of Reproduction
  
  Volume: 102(3) Pages: 620-638
- DOI
  10.1093/biolre/ioz205
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06030, KAKENHI-PROJECT-19K16013, KAKENHI-PROJECT-19H03618, KAKENHI-PROJECT-17K08135
[Journal Article] ZGLP1 is a determinant for the oogenic fate in mice2020
- Author(s)
  Nagaoka So I.、Nakaki Fumio、Miyauchi Hidetaka、Nosaka Yoshiaki、Ohta Hiroshi、Yabuta Yukihiro、Kurimoto Kazuki、Hayashi Katsuhiko、Nakamura Tomonori、Yamamoto Takuya、Saitou Mitinori
- Journal Title
  
  Science
  
  Volume: 367 Pages: 1089-1089
- DOI
  10.1126/science.aaw4115
- NAID
  120006850276
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19295, KAKENHI-PLANNED-18H05553, KAKENHI-PROJECT-19H03618, KAKENHI-PROJECT-20K15801
[Journal Article] Induction of fetal primary oocytes and the meiotic prophase from mouse pluripotent stem cells2018
- Author(s)
  Miyauchi H, Ohta H, Saitou M.
- Journal Title
  
  Methods in Cell Biology
  
  Volume: 144 Pages: 409-429
- DOI
  10.1016/bs.mcb.2018.03.035
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05636, KAKENHI-PROJECT-17H06098
[Journal Article] Expansion of mouse primordial germ cell-like cells in culture reconstitutes an epigenetic blank slate.2017
- Author(s)
  Hiroshi Ohta, Kazuki Kurimoto, Ikuhiro Okamoto, Tomonori Nakamura, Yukihiro Yabuta, Hidetaka Miyauchi, Takuya Yamamoto, Yukiko Okuno, Masatoshi Hagiwara, Kenjiro Shirane, Hiroyuki Sasaki, Mitinori Saitou.
- Journal Title
  
  The EMBO Journal
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H05636
[Journal Article] Expansion of mouse primordial germ cell-like cells in culture reconstitutes an epigenetic blank slate.2017
- Author(s)
  Ohta H, Kurimoto K, Okamoto I, Nakamura T, Yabuta Y, Miyauchi H, Yamamoto T, Okuno Y, and Hagiwara M, Shirane K, Sasaki H, Saitou M.
- Journal Title
  
  EMBO J.
  
  Volume: 36 Issue: 13 Pages: 1888-1907
- DOI
  10.15252/embj.201695862
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01216, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112010, KAKENHI-PROJECT-16H04720, KAKENHI-PROJECT-15H05636, KAKENHI-PROJECT-21249013, KAKENHI-PROJECT-17H06098
[Journal Article] Fertile offspring from sterile sex chromosome trisomic mice.2017
- Author(s)
  Hirota Takayuki、Ohta Hiroshi、Powell Benjamin E.、Mahadevaiah Shantha K.、Ojarikre Obah A.、Saitou Mitinori、Turner James M. A.
- Journal Title
  
  Science
  
  Volume: 357 Pages: 932-935
- DOI
  10.1126/science.aam9046
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05636, KAKENHI-PROJECT-17H06098
[Journal Article] Bone morphogenetic protein and retinoic acid synergistically specify female germ-cell fate in mice.2017
- Author(s)
  Miyauchi Hidetaka、Ohta Hiroshi、Nagaoka So、Nakaki Fumio、Sasaki Kotaro、Hayashi Katsuhiko、Yabuta Yukihiro、Nakamura Tomonori、Yamamoto Takuya、Saitou Mitinori
- Journal Title
  
  EMBO Journal
  
  Volume: 36 Pages: 3100-3119
- DOI
  10.15252/embj.201796875
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25114006, KAKENHI-PROJECT-15H05636, KAKENHI-PROJECT-16K14740, KAKENHI-INTERNATIONAL-15K21736, KAKENHI-PROJECT-17H01395, KAKENHI-PROJECT-17H06098
[Journal Article] Induction of the mouse germ cell fate by transcription factors in vitro2013
- Author(s)
  Nakaki F, Hayashi K, Ohta H, Kurimoto K, Yabuta Y, Saitou M.
- Journal Title
  
  Nature
  
  Volume: 501 Pages: 222-226
- DOI
  10.1038/nature12417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J03853, KAKENHI-PROJECT-21677003, KAKENHI-PROJECT-24680045, KAKENHI-PROJECT-24681039, KAKENHI-PROJECT-25290033, KAKENHI-PROJECT-25650065, KAKENHI-PROJECT-25650077
[Patent] 始原生殖細胞/始原生殖細胞様細胞の維持増幅及び分化誘導方法2017
- Inventor(s)
  斎藤通紀、大田浩、宮内英孝
- Industrial Property Rights Holder
  京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-231294
- Filing Date
  2017-11-30
- Data Source
  KAKENHI-PROJECT-24680045

1. 本多新 (10373367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 磯谷綾子 (20444523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 的場章悟 (20585202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. NAKAMURA Toshinobu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 栗本一基

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
6. 齋藤都暁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 佐々木裕之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 萩原正敏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 斎藤通紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
10. 中村紳一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 林克彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 岡本郁弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 築山智之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohta Hiroshi 大田 浩

OHTA Hiroshi 大田 浩

Research Projects

Research Products

Co-Researchers

Elucidation of the gene expression cascade responsible for male sexuality and acquisition of fertility

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

試験管内において卵子形成の支持が可能な卵巣体細胞の新規培養法の確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of culture system for inducing oocytes from primordial germ cell-like cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of efficient induction system for primordial germ cells from ES cells in vitroPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of proliferation and differentiation of primordial germ cell-like cells derived from ES cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of novel technique using primordial germ cells induced from embryonic stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cyclosporin A and FGF signaling support the proliferation/survival of mouse primordial germ cell-like cells in vitro2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Long‐term expansion with germline potential of human primordial germ cell‐like cells in vitro2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Induction of the germ cell fate from pluripotent stem cells in cynomolgus monkeys†2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ZGLP1 is a determinant for the oogenic fate in mice2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Induction of fetal primary oocytes and the meiotic prophase from mouse pluripotent stem cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expansion of mouse primordial germ cell-like cells in culture reconstitutes an epigenetic blank slate.2017

Author(s)

Journal Title

Data Source

[Journal Article] Expansion of mouse primordial germ cell-like cells in culture reconstitutes an epigenetic blank slate.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fertile offspring from sterile sex chromosome trisomic mice.2017

Author(s)

Journal Title

DOI

Ohta Hiroshi 大田浩

OHTA Hiroshi 大田浩