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Ohta Hiroshi  大田 浩

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OHTA Hiroshi  大田 浩

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Researcher Number 50391892
Other IDs
Affiliation (Current) 2022: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help 2018 – 2022: 京都大学, 医学研究科, 准教授
2016 – 2018: 京都大学, 医学研究科, 助教
2013 – 2015: 京都大学, 医学(系)研究科(研究院), 助教
2012: 京都大学, 医学研究科, 助教
Review Section/Research Field
Principal Investigator
Laboratory animal science / Laboratory animal science / Integrative animal science / Basic Section 52050:Embryonic medicine and pediatrics-related / Medium-sized Section 48:Biomedical structure and function and related fields
Except Principal Investigator
Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
Keywords
Principal Investigator
始原生殖細胞 / ES細胞 / 卵子形成 / 培養 / 分化誘導 / 増殖 / 分化 / 細胞分化 / 試験管内 / 再構成卵巣 … More / 小分子化合物 / 増殖・分化 / 精子形成 / chemical libray / high-throughput screening / EpiLC / 配偶子形成 / 細胞培養 / 細胞増殖 / 卵母細胞 / 卵原細胞 / 始原生殖細胞様細胞 / 試験管内誘導 / ヒト / 多能性幹細胞 / 胎生期生殖巣 / iPS細胞 / in vitro / 生殖巣 / 体細胞 / 支持細胞 … More
Except Principal Investigator
性決定 / 絶滅危惧種 / iPS細胞 / 生殖巣 / 生殖細胞 Less
  • Research Projects

    (6 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (13 People)
  •  Elucidation of the gene expression cascade responsible for male sexuality and acquisition of fertility

    • Principal Investigator
      本多 新
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
    • Research Institution
      Jichi Medical University
      Kyoto University
  •  試験管内において卵子形成の支持が可能な卵巣体細胞の新規培養法の確立Principal Investigator

    • Principal Investigator
      大田 浩
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 48:Biomedical structure and function and related fields
    • Research Institution
      Kyoto University
  •  Establishment of culture system for inducing oocytes from primordial germ cell-like cellsPrincipal Investigator

    • Principal Investigator
      大田 浩
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Kyoto University
  •  Establishment of efficient induction system for primordial germ cells from ES cells in vitroPrincipal Investigator

    • Principal Investigator
      Ohta Hiroshi
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Laboratory animal science
    • Research Institution
      Kyoto University
  •  Analysis of proliferation and differentiation of primordial germ cell-like cells derived from ES cellsPrincipal Investigator

    • Principal Investigator
      Ohta Hiroshi
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Integrative animal science
    • Research Institution
      Kyoto University
  •  Establishment of novel technique using primordial germ cells induced from embryonic stem cellsPrincipal Investigator

    • Principal Investigator
      OHTA Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Laboratory animal science
    • Research Institution
      Kyoto University

All 2020 2018 2017 2013

All Journal Article Patent

  • [Journal Article] Cyclosporin A and FGF signaling support the proliferation/survival of mouse primordial germ cell-like cells in vitro2020

    • Author(s)
      Ohta Hiroshi、Yabuta Yukihiro、Kurimoto Kazuki、Nakamura Tomonori、Murase Yusuke、Yamamoto Takuya、Saitou Mitinori
    • Journal Title

      Biology of Reproduction

      Volume: 104 Pages: 344-360

    • DOI

      10.1093/biolre/ioaa195

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21500, KAKENHI-PLANNED-18H05553, KAKENHI-PROJECT-20H00471, KAKENHI-PROJECT-19H03618, KAKENHI-PROJECT-18K19295
  • [Journal Article] Long‐term expansion with germline potential of human primordial germ cell‐like cells in vitro2020

    • Author(s)
      Murase Yusuke、Yabuta Yukihiro、Ohta Hiroshi、Yamashiro Chika、Nakamura Tomonori、Yamamoto Takuya、Saitou Mitinori
    • Journal Title

      The EMBO Journal

      Volume: 39

    • DOI

      10.15252/embj.2020104929

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21500, KAKENHI-PROJECT-19H03618
  • [Journal Article] Induction of the germ cell fate from pluripotent stem cells in cynomolgus monkeys†2020

    • Author(s)
      Sakai Y, Nakamura T, Okamoto I, Gyobu-Motani S, Ohta H, Yabuta Y, Tsukiyama T, Iwatani C, Tsuchiya H, Ema M, Morizane A, Takahashi J, Yamamoto T, Saitou M.
    • Journal Title

      Biology of Reproduction

      Volume: 102(3) Pages: 620-638

    • DOI

      10.1093/biolre/ioz205

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06030, KAKENHI-PROJECT-19K16013, KAKENHI-PROJECT-19H03618, KAKENHI-PROJECT-17K08135
  • [Journal Article] ZGLP1 is a determinant for the oogenic fate in mice2020

    • Author(s)
      Nagaoka So I.、Nakaki Fumio、Miyauchi Hidetaka、Nosaka Yoshiaki、Ohta Hiroshi、Yabuta Yukihiro、Kurimoto Kazuki、Hayashi Katsuhiko、Nakamura Tomonori、Yamamoto Takuya、Saitou Mitinori
    • Journal Title

      Science

      Volume: 367 Pages: 1089-1089

    • DOI

      10.1126/science.aaw4115

    • NAID

      120006850276

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19295, KAKENHI-PLANNED-18H05553, KAKENHI-PROJECT-19H03618, KAKENHI-PROJECT-20K15801
  • [Journal Article] Induction of fetal primary oocytes and the meiotic prophase from mouse pluripotent stem cells2018

    • Author(s)
      Miyauchi H, Ohta H, Saitou M.
    • Journal Title

      Methods in Cell Biology

      Volume: 144 Pages: 409-429

    • DOI

      10.1016/bs.mcb.2018.03.035

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05636, KAKENHI-PROJECT-17H06098
  • [Journal Article] Expansion of mouse primordial germ cell-like cells in culture reconstitutes an epigenetic blank slate.2017

    • Author(s)
      Hiroshi Ohta, Kazuki Kurimoto, Ikuhiro Okamoto, Tomonori Nakamura, Yukihiro Yabuta, Hidetaka Miyauchi, Takuya Yamamoto, Yukiko Okuno, Masatoshi Hagiwara, Kenjiro Shirane, Hiroyuki Sasaki, Mitinori Saitou.
    • Journal Title

      The EMBO Journal

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H05636
  • [Journal Article] Expansion of mouse primordial germ cell-like cells in culture reconstitutes an epigenetic blank slate.2017

    • Author(s)
      Ohta H, Kurimoto K, Okamoto I, Nakamura T, Yabuta Y, Miyauchi H, Yamamoto T, Okuno Y, and Hagiwara M, Shirane K, Sasaki H, Saitou M.
    • Journal Title

      EMBO J.

      Volume: 36 Issue: 13 Pages: 1888-1907

    • DOI

      10.15252/embj.201695862

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-16H01216, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112010, KAKENHI-PROJECT-16H04720, KAKENHI-PROJECT-15H05636, KAKENHI-PROJECT-21249013, KAKENHI-PROJECT-17H06098
  • [Journal Article] Fertile offspring from sterile sex chromosome trisomic mice.2017

    • Author(s)
      Hirota Takayuki、Ohta Hiroshi、Powell Benjamin E.、Mahadevaiah Shantha K.、Ojarikre Obah A.、Saitou Mitinori、Turner James M. A.
    • Journal Title

      Science

      Volume: 357 Pages: 932-935

    • DOI

      10.1126/science.aam9046

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H05636, KAKENHI-PROJECT-17H06098
  • [Journal Article] Bone morphogenetic protein and retinoic acid synergistically specify female germ-cell fate in mice.2017

    • Author(s)
      Miyauchi Hidetaka、Ohta Hiroshi、Nagaoka So、Nakaki Fumio、Sasaki Kotaro、Hayashi Katsuhiko、Yabuta Yukihiro、Nakamura Tomonori、Yamamoto Takuya、Saitou Mitinori
    • Journal Title

      EMBO Journal

      Volume: 36 Pages: 3100-3119

    • DOI

      10.15252/embj.201796875

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-25114006, KAKENHI-PROJECT-15H05636, KAKENHI-PROJECT-16K14740, KAKENHI-INTERNATIONAL-15K21736, KAKENHI-PROJECT-17H01395, KAKENHI-PROJECT-17H06098
  • [Journal Article] Induction of the mouse germ cell fate by transcription factors in vitro2013

    • Author(s)
      Nakaki F, Hayashi K, Ohta H, Kurimoto K, Yabuta Y, Saitou M.
    • Journal Title

      Nature

      Volume: 501 Pages: 222-226

    • DOI

      10.1038/nature12417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J03853, KAKENHI-PROJECT-21677003, KAKENHI-PROJECT-24680045, KAKENHI-PROJECT-24681039, KAKENHI-PROJECT-25290033, KAKENHI-PROJECT-25650065, KAKENHI-PROJECT-25650077
  • [Patent] 始原生殖細胞/始原生殖細胞様細胞の維持増幅及び分化誘導方法2017

    • Inventor(s)
      斎藤通紀、大田浩、宮内英孝
    • Industrial Property Rights Holder
      京都大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-231294
    • Filing Date
      2017-11-30
    • Data Source
      KAKENHI-PROJECT-24680045
  • 1.  本多 新 (10373367)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  磯谷 綾子 (20444523)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  的場 章悟 (20585202)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  NAKAMURA Toshinobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  栗本 一基
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 4 results
  • 6.  齋藤 都暁
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  佐々木 裕之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  萩原 正敏
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  斎藤 通紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 5 results
  • 10.  中村 紳一朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 11.  林 克彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 12.  岡本 郁弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  築山 智之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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