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Naoe Yoshinori  直江 吉則

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NAOE Yoshinori  直江 吉則

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Researcher Number 50392048
Other IDs
Affiliation (Current) 2022: 名古屋大学, 医学系研究科, 特任准教授
2022: 国立研究開発法人国立長寿医療研究センター, その他部局等, その他
Affiliation (based on the past Project Information) *help 2018 – 2022: 名古屋大学, 医学系研究科, 特任准教授
2017: 名古屋大学, 医学系研究科, 特任講師
2015: 国立研究開発法人国立長寿医療研究センター, 運動器疾患研究部, 流動研究員
2014: 独立行政法人国立長寿医療研究センター, 老化機構研究部, 流動研究員
2014: 国立長寿医療研究センター研究所, 研究員 … More
2014: 独立行政法人国立長寿医療センター, 老化機構研究部免疫研究室, 室長
2013: 独立行政法人国立長寿医療研究センター, 老化機構研究部, 室長
2011: 独立行政法人国立長寿医療研究センター, 研究所老化機構研究部免疫研究室, 室長
2011: 独立行政法人国立長寿医療研究センター, 老化機構研究部・免疫研修室, 室長
2010: 独立行政法人国立長寿医療研究センター, 老化機構研究部・免疫研究室, 室長
2009: National Institute for Longevity Sciences,NCGG, 老化機構研究部免疫研究室, 室長 Less
Review Section/Research Field
Principal Investigator
Pathological medical chemistry / Surgery of the organs maintaining homeostasis and related fields / Basic Section 49010:Pathological biochemistry-related
Except Principal Investigator
Immunology / Laboratory animal science / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55020:Digestive surgery-related
Keywords
Principal Investigator
細胞障害性T細胞 / T細胞 / 免疫学 / マイクロアレイ / ヘルパーT細胞 / ThPOK / CXXC5 / エピジェネティクス / T細胞 / Cxxc5 … More / iPS細胞 / 癌免疫 / 癌抗原 / iPS / T細胞レセプター / がん抗原 / 腫瘍溶解性ウイルス / 腸内細菌叢 / 抗腫瘍効果 / 免疫 / 癌 … More
Except Principal Investigator
ユビキチン / MHC class II / 樹状細胞 / 抗原提示 / CD86 / 寛容 / IgE / マクロファージ / 糖尿病 / 炎症 / トランスジェニックマウス / ノックアウトマウス / 脂肪組織 / 遺伝子発現 / 糖代謝 / 遺伝子組換えマウス / 核内タンパク質 / 慢性炎症 / 2型糖尿病 / 遺伝子組み換えマウス / 肥満 / ob/obマウス / 腫瘍溶解性ウイルス / 癌免疫 / C-REV / 腫瘍溶解性ウィルス / CAR-T cell / 膵癌 Less
  • Research Projects

    (8 results)
  • Research Products

    (59 results)
  • Co-Researchers

    (20 People)
  •  固形癌に対するCAR-T、ウイルス療法の併用による新規免疫療法の開発

    • Principal Investigator
      粕谷 英樹
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Nagoya University
  •  Role of intestinal flora on the antitumor immunity of oncolytic virusesPrincipal Investigator

    • Principal Investigator
      直江 吉則
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Nagoya University
  •  癌を支える癌関連間葉系幹細胞の癌ワクチンへの標的化

    • Principal Investigator
      松村 繁
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Nagoya University
  •  TCR sequencing of tumor infiltrating T cells using iPS cell technologyPrincipal Investigator

    • Principal Investigator
      Naoe Yoshinori
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Research Field
      Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Nagoya University
  •  ThPOK represses CXXC5, which inhibits CD40L expression in cytotoxic T cells through epigenetic regulationPrincipal Investigator

    • Principal Investigator
      Naoe Yoshinori
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  Novel immune regulation through regulated MHC II ubiquitination

    • Principal Investigator
      ISHIDO Satoshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Showa Pharmaceutical University
  •  Modulatory effects of macrophage M-mod/USP2 on type2 diabetes

    • Principal Investigator
      KITAMURA Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Rakuno Gakuen University
      Nagoya City University
  •  Identification of Runx transcriptional factors target genes in regulatory T cell.Principal Investigator

    • Principal Investigator
      NAOE Yoshinori
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      National Center for Geriatrics and Gerontology

All 2021 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book

  • [Book] 遺伝子医学MOOK 31号 がん免疫療法 - What's now and what's next? 第2章の4の3) 腫瘍溶解性ウイルスHF10による再発乳がん多発結節症例, 切除不能進行膵がん症例に対する臨床研究2017

    • Author(s)
      粕谷 英樹, 直江 吉則, 一ノ瀬 亨, 廣岡 芳樹, 後藤 秀実, 田中 舞紀
    • Total Pages
      294
    • Publisher
      (株)メディカル ドゥ
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Book] 免疫の辞典2012

    • Author(s)
      直江吉則
    • Publisher
      朝倉書店
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Journal Article] Oncolytic herpes simplex virus HF10 (canerpaturev, C-REV) promotes accumulation of CD8+PD-1- tumor-infiltrating T cells in PD-L1 enriched tumor microenvironment.2021

    • Author(s)
      Eissa I.R., Mukoyama N., Abdelmoneim, M., Naoe, Y., Matsumura, S., Bustos-Villalobos I., Ichinose T., Miyajima N., Morimoto D., Tanaka M., Fujimoto, Y., Kodera Y., Kasuya H.
    • Journal Title

      Int. J. Cancer

      Volume: 1 Pages: 1-14

    • DOI

      10.1002/ijc.33550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18H02691
  • [Journal Article] The Current Status and Future Prospects of Oncolytic Viruses Clinical Trials against Melanoma,Glioma,Pancreatic and Breast cancers.2018

    • Author(s)
      Eissa Ibrahim、Bustos-Villalobos Itzel、Ichinose Toru、Matsumura Shigeru、Naoe Yoshinori、Miyajima Noriyuki、Morimoto Daishi、Mukoyama Nobuaki、Zhiwen Wu、Tanaka Maki、Hasegawa Hitoki、Sumigama Seiji、Aleksic Branko、Kodera Yasuhiro、Kasuya Hideki
    • Journal Title

      Cancers

      Volume: 10 Pages: 1-22

    • DOI

      10.3390/cancers10100356

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15274, KAKENHI-PROJECT-16H05413, KAKENHI-PROJECT-18H02691, KAKENHI-PROJECT-17K19696, KAKENHI-PROJECT-17K16907
  • [Journal Article] A Phase I clinical trial of EUS-guided intratumoral injection of the oncolytic virus, HF10 for unresectable locally advanced pancreatic cancer.2018

    • Author(s)
      Hirooka Yoshiki、Kasuya Hideki、Ishikawa Takuya、Kawashima Hiroki、Ohno Eizaburo、Villalobos Itzel B.、Naoe Yoshinori、Ichinose Toru、Koyama Nobuto、Tanaka Maki、Kodera Yasuhiro、Goto Hidemi
    • Journal Title

      BMC Cancer

      Volume: 18 Pages: 596-596

    • DOI

      10.1186/s12885-018-4453-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15274, KAKENHI-PROJECT-16H05413, KAKENHI-PROJECT-17K19696, KAKENHI-PROJECT-17K16907
  • [Journal Article] Priming of lineage-specifying genes by Bcl11b is required for lineage choice in post-selection thymocytes2017

    • Author(s)
      Kojo S, Tanaka H, Endo TA, Muroi S, Liu Y, Seo W, Tenno M, Kakugawa K, Naoe Y, Nair K, Moro K, Katsuragi Y, Kanai A, Inaba T, Egawa T, Venkatesh B, Minoda A, Kominami R, Taniuchi I.
    • Journal Title

      Nature Communications

      Volume: 8 Pages: 1-14

    • DOI

      10.1038/s41467-017-00768-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19696, KAKENHI-PUBLICLY-17H05805, KAKENHI-PROJECT-15H04857, KAKENHI-PROJECT-15K08291, KAKENHI-PROJECT-16K15362, KAKENHI-PROJECT-15K08535
  • [Journal Article] Genomic Signature of the Natural Oncolytic Herpes Simplex Virus HF10 and Its Therapeutic Role in Preclinical and Clinical Trials.2017

    • Author(s)
      Eissa IR, Naoe Y, Bustos-Villalobos I, Ichinose T, Tanaka M, Zhiwen W, Mukoyama N, Morimoto T, Miyajima N, Hitoki H, Sumigama S, Aleksic B, Kodera Y, Kasuya H.
    • Journal Title

      Front Oncol.

      Volume: 7 Pages: 147-147

    • DOI

      10.3389/fonc.2017.00149

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19696, KAKENHI-PROJECT-16H05413
  • [Journal Article] ThPOK represses CXXC5, which induces methylation of histone H3 lysine 9 in Cd40lg promoter by association with SUV39H1: implications in repression of CD40L expression in CD8+ cytotoxic T cells2016

    • Author(s)
      Tsuchiya Y, Naito T, Tenno M, Maruyama M, Koseki H, Taniuchi I, Naoe Y.
    • Journal Title

      J Leukoc Biol.

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25460401
  • [Journal Article] Proliferation-coupled osteoclast differentiation by RANKL: cell density as a determinant of osteoclast function2015

    • Author(s)
      Motiur Rahman M, Takeshita S, Matsuoka K, Kaneko K, Naoe Y, Sakaue-Sawano A, Miyawaki A, Ikeda K.
    • Journal Title

      Bone

      Volume: 81 Pages: 392-399

    • DOI

      10.1016/j.bone.2015.08.008

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25440095, KAKENHI-PROJECT-25460401, KAKENHI-PROJECT-26670182
  • [Journal Article] A novel Cd8-cis regulatory element that directs expression in CD44+CD62L+CD8+ T cells and in CD8aa+ dendritic cells.2015

    • Author(s)
      Sakaguchi S, Hombauer M, Hassan H, Tanaka H, Yasmin N, Naoe Y, Bilic I, Moser MA, Hainberger D, Mayer H, Seiser C, Bergthaler A, Taniuchi I, Ellmeier W.
    • Journal Title

      J. Leukoc. Biol.

      Volume: 97 Pages: 635-44

    • DOI

      10.1189/jlb.1hi1113-597rr

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460401, KAKENHI-PUBLICLY-26114720, KAKENHI-PROJECT-26293109
  • [Journal Article] Ubiquitin-specific protease 2-69 in macrophages potentially modulates metainflammation2013

    • Author(s)
      Kitamura et al.
    • Journal Title

      FASEB J

      Volume: 27 Pages: 2940-2953

    • DOI

      10.1096/fj.13-233528

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-24117723, KAKENHI-PROJECT-24500494, KAKENHI-PROJECT-24500495, KAKENHI-PROJECT-25293114, KAKENHI-PROJECT-25460261, KAKENHI-PROJECT-25460401
  • [Journal Article] Beneficial effects of Brazilian propolis on type 2 diabetes in ob/ob mice: Possible involvement of immune cells in mesenteric adipose tissue.2013

    • Author(s)
      Kitamura H, Naoe Y, Kimura S, Miyamoto T, Okamoto S, Toda C, Shimamoto Y, Iwanaga T, Miyoshi I
    • Journal Title

      Adipocyte

      Volume: 2 Pages: 227-236

    • DOI

      10.4161/adip.25608

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500494, KAKENHI-PROJECT-24500495, KAKENHI-PROJECT-25460261, KAKENHI-PROJECT-25460401
  • [Journal Article] Transcriptional control of T-cell development2011

    • Author(s)
      直江吉則
    • Journal Title

      Int Immunol

      Volume: 23 Pages: 661-668

    • Data Source
      KAKENHI-PROJECT-21590348
  • [Journal Article] Transcriptional control of T-cell development2011

    • Author(s)
      Naito T、Tanaka H、Naoe Y and Taniuchi I
    • Journal Title

      InternaInternaI Immunology

      Volume: 23 Pages: 661-668

    • Data Source
      KAKENHI-PROJECT-21590348
  • [Journal Article] The zinc finger protein MAZR is part of the transcription factor network controlling CD4/CD8 cell fate decision of DP thymocytes.2010

    • Author(s)
      直江吉則
    • Journal Title

      Nature Immunology

      Volume: 11 Pages: 442-448

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Journal Article] The zinc finger protein MAZR is part of the transcription factor network controlling CD4/CD8 cell fate decision of DP thymocytes2010

    • Author(s)
      Sakaguchi S、Hombauer M、Bilic I、Naoe Y、Schebesta A、Taniuchi I andEllmeier W
    • Journal Title

      Nat Immunol

      Volume: 11 Pages: 442-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Journal Article] Chromatin binding of SRp20 and ASF/SF2 and dissociation from mitotic chromatin is modulated by histone H3 serin 10 phosphorylation.2009

    • Author(s)
      直江吉則
    • Journal Title

      Molecular cell 33

      Pages: 450-461

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Journal Article] Runx proteins regulate FoxP3 expression2009

    • Author(s)
      Bruno L、Mazzarella L、Hoogenkamp M、Hertweck A、Cobb BS、Sauer S、Hadjur S、Leleu M、Naoe Y、Telfer J、Bonifer C、Taniuchi I、Fisher AG and Merkenschlager M
    • Journal Title

      J Exp Med

      Volume: 206 Pages: 2329-37

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Journal Article] Indispensable role of Runx1/Cbfβ complex for in vivo suppressive function for FoxP3^+ regulatory T cells.2009

    • Author(s)
      直江吉則
    • Journal Title

      Immunity 31

      Pages: 609-620

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Journal Article] Runx proteins regulate FoxP3 expression.2009

    • Author(s)
      直江吉則
    • Journal Title

      Journal of experimental medicine 206

      Pages: 2329-2337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Journal Article] Indispensable role of Runx1/Cbfβcomplex for in vivo suppressive function for FoxP3+regulatory T cells2009

    • Author(s)
      Kitoh A、Ono M、Naoe Y、Ohkura N、Yamaguchi T、Yaguchi H、Kitabayashi I、Tsukada T、Nomura T、Miyamachi Y、Taniuchi I and Sakaguchi S
    • Journal Title

      Immunity

      Volume: 16 Pages: 1-12

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Presentation] Combination therapy of Cetuximab and CANERPATUREV suppresses human colorectal cancer growth2019

    • Author(s)
      Shigeru Matsumura, Zhiwen Wu, Toru Ichinose, Yoshinori Naoe, Itzel Bustos Villalobos, Ibrahim Ragab Eissa, Suguru Yamada, Yasuhiro Kodera, Maki Tanaka, and Hideki Kasuya
    • Organizer
      日本遺伝子細胞治療学会
    • Data Source
      KAKENHI-PROJECT-18H02691
  • [Presentation] 大腸癌モデルにおけるセツキシマブとC-REVとの併用治療効果について2019

    • Author(s)
      Shigeru Matsumura, Zhiwen Wu, Toru Ichinose, Yoshinori Naoe, Itzel Bustos Villalobos, Ibrahim Ragab Eissa, Suguru Yamada, Yasuhiro Kodera, Maki Tanaka, and Hideki Kasuya
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-18H02691
  • [Presentation] Combination of cetuximab and oncolytic virus canepaturev synergistically inhibits human colorectal cancer growth2019

    • Author(s)
      Shigeru Matsumura, Zhiwen Wu, Toru Ichinose, Yoshinori Naoe, Itzel Bustos Villalobos, Ibrahim Ragab Eissa, Suguru Yamada, Yasuhiro Kodera, Maki Tanaka, and Hideki Kasuya
    • Organizer
      癌免疫学会
    • Data Source
      KAKENHI-PROJECT-18H02691
  • [Presentation] STING is dispensable for low susceptibility to C-REV (HF10) in pancreatic cancer cell lines2018

    • Author(s)
      Matsumura S, Morimoto D, Naoe Y, Ichinose T, Eissa IR, Tanaka M, Kodera Y, Kasuya H
    • Organizer
      日本癌学会
    • Data Source
      KAKENHI-PROJECT-18H02691
  • [Presentation] The synergistic effect of the combination therapy of PD-L1 immune checkpoint inhibitor and oncolytic herpes simplex virus HF102018

    • Author(s)
      Nobuaki Mukoyama, Ibrahim Eissa, Yoshinori Naoe, Toru Ichinose, Shigeru Matsumura, Itzel Bustos, Wu Zhiwen, Noriyuki Miyajima, Daishi Morimoto, Maki Tanaka, Yasushi Fujimoto, Michihiko Sone, Yasuhiro Kodera, Hideki Kasuya
    • Organizer
      第24回日本遺伝子細胞治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] STING is dispensable for low susceptibility to C-REV(HF10) in pancreatic cancer cell lines2018

    • Author(s)
      Shigeru Matsumura, Daishi Morimoto, Yoshinori Naoe, Toru Ichinose, Maki Tanaka, Yasuhiro Kodera, Hideki Kasuya
    • Organizer
      4th ONCOLYTIC VIROTHERAPY Summit
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] Does the expression level of STING correlate with susceptibility to oncolytic virus HF10 in human pancreatic cell lines?2018

    • Author(s)
      Daishi Morimoto, Yoshinori Naoe, Shigeru Matsumura, Toru Ichinose, Ibrahim Eissa, Itzel Bustos, Noriyuki Miyajima, Nobuaki Mukoyama, Wu Zhiwen, Maki Tanaka, Yasuhiro Kodera, Hideki Kasuya
    • Organizer
      第24回日本遺伝子細胞治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] Clinical trial using HF10 with Gemcitabine and Erlotinib for 9 patients of Unresectable pancreatic cancer2018

    • Author(s)
      Hideki Kasuya, Yoshiki Hirooka, Yoshinori Naoe, Shigeru Matsumura, Itzel Bustos, Toru Ichinose, Ibrahim Eissa, Wu Zhiwen, Nobuaki Mukoyama, Noriyuki Miyajima, Daishi Morimoto, Hidemi Goto, Maki Tanaka
    • Organizer
      第56回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] Final total Data of Clinical trial using HF10 with Gemcitabine and Erlotinib against Unresectable Pancreatic Cancer2018

    • Author(s)
      Hideki Kasuya, Yoshiki Hirooka, Yoshinori Naoe, Shigeru Matsumura, Itzel Bustos, Toru Ichinose, Ibrahim Eissa, Wu Zhiwen, Nobuaki Mukoyama, Noriyuki Miyajima, Daishi Morimoto, Hidemi Goto, Maki Tanaka
    • Organizer
      第24回日本遺伝子細胞治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] Combination therapy of oncolytic HSV HF10 and immune checkpoint inhibitor2018

    • Author(s)
      H Kasuya, Y Naoe, S Matsumura, I Bustos, T Ichinose, I Eissa, W Zhiwen, N Miyajima, D Morimoto, M Tanaka
    • Organizer
      International Oncolytic Virus Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] The synergistic effect of the combination therapy of PD-L1 immune checkpoint inhibitor and oncolytic herpes simplex virus Canerpaturev(C-REV)2018

    • Author(s)
      Yoshinori Naoe, Nobuaki Mukoyama, Ibrahim Eissa, Toru Ichinose, Shigeru Matsumura, Itzel Bustos, Wu Zhiwen, Noriyuki Miyajima, Daishi Morimoto, Maki Tanaka, Yasushi Fujimoto, Michihiko Sone, Yasuhiro Kodera, Hideki Kasuya
    • Organizer
      第56回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] STING is dispensable for low susceptibility to C-REV (HF10) in pancreatic cancer cell lines2018

    • Author(s)
      Matsumura S, Morimoto D, Naoe Y, Ichinose T, Eissa IR, Tanaka M, Kodera Y, Kasuya H
    • Organizer
      4th Annual Oncolytic virotherapy summit
    • Data Source
      KAKENHI-PROJECT-18H02691
  • [Presentation] Involvement of cGAS and STING in sensitivity to oncolytic virus HF10 in breast cancer cell lines2018

    • Author(s)
      Noriyuki Miyajima, Yoshinori Naoe, Shigeru Matsumura, Itzel Bustos, Toru Ichinose, Ibrahim Eissa, Wu Zhiwen, Nobuaki Mukoyama, Daishi Morimoto, Maki Tanaka, Hideki Kasuya
    • Organizer
      第24回日本遺伝子細胞治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] Systemic therapeutic potential of oncolytic herpes simplex virus HF10 adsorbed on antigen-specific lymphocytes2017

    • Author(s)
      Ichinose T, Naoe Y, Nassr E. I. R, Luo C, Villalobos I. B, Zhiwen W, Mukoyama N, Miyajima N, Morimoto D, Yamada S, Fujii T, Sugimoto H, Tanaka M, Kodera Y, Kasuya H.,
    • Organizer
      第23回日本遺伝子細胞治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] Combination therapy of PD-L1 immune checkpoint inhibitor and oncolytic herpes simplex virus HF102017

    • Author(s)
      森本 大士, 直江 吉則, 向山 宜明, 一ノ瀬 亨, Itzel Bustos Villalobos, 神田 光郎, 丹羽 由紀子, 岩田 直樹, 林 真路, 小林 大介, 田中 千恵, 中山 吾郎, 山田 豪, 杉本 博行, 小池 聖彦, 藤原 道隆, 田中 舞紀, 藤本 保志, 粕谷 英樹, 小寺 泰
    • Organizer
      第28回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] ヒト膵癌異種移植モデルにおけるnab-Paclitaxel(nab-PTX)と腫瘍溶解性単純ヘルペスウイルスHF10 との併用療法2017

    • Author(s)
      森本 大士, 直江 吉則, 一ノ瀬 亨, Bustos Itzel, 神田 光郎, 丹羽 由紀子, 岩田 直樹, 林 真路, 小林 大介, 田中 千恵, 山田 豪, 中山 吾郎, 杉本 博行, 小池 聖彦, 藤原 道隆, 藤井 努, 田中 舞紀, 粕谷 英樹, 小寺 泰弘
    • Organizer
      第117 回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] COMBINATION THERAPY AGAINST HUMAN COLORECTAL CANCER WITH THE EPIDERMAL GROWTH FACTOR RECEPTOR INHIBITOR CETUXIMAB AND ONCOLYTIC HERPES SIMPLEX VIRUS HF102017

    • Author(s)
      呉 智聞, 一ノ瀬 亨, 駱 晨虹, 直江 吉則, ヴィラロボス イッツェル・バストス, 山田 豪, 杉本 博行, 宮嶋 則行, 森本 大士, 向山 宣昭, 西川 洋子, 小出 悠介, 小寺 泰弘, 田中 舞紀, 粕谷 英樹
    • Organizer
      第55回日本癌治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] 腫瘍溶解性単純ヘルペスウイルスHF10と免疫チェックポイント阻害剤の併用2017

    • Author(s)
      森本 大士, 直江 吉則, 向山 宜明, 宮嶋 則行, Ibrahim Ragab Eissa, 一ノ瀬 亨, Itzel Bustos-Villalobos, 山田 豪, 田中 舞紀, 藤本 保志, 小寺 泰弘, 粕谷 英樹
    • Organizer
      第51回制癌剤適応研究会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] Combination therapy of PD-L1 immune checkpoint inhibitor and oncolytic herpes simplex virus HF102017

    • Author(s)
      Mukoyama N, Naoe Y, Ichinose T, Nassr E. I. R, Luo C, Villalobos I. B, Zhiwen W, Miyajima N, Morimoto D, Tanaka M, Fujimoto Y, Sone M, Kodera Y, Kasuya H.
    • Organizer
      第23回日本遺伝子細胞治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] HF10 ウイルス療法におけるin situ vaccination効果についての検討2017

    • Author(s)
      粕谷 英樹, 直江 吉則, Bustos Itzel, 一ノ瀬 亨, 森本 大士, 向山 宣昭, 呉 智聞, 藤井 努, 小寺 泰弘, 田中 舞紀
    • Organizer
      第117 回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] Combination therapy against human pancreatic cancer with oncolytic herpes virus HF10 and abraxane2017

    • Author(s)
      Wu Z, Ichinose T, Luo C, Naoe Y, Villalobos I. B, Yamada S, Fujii T, Sugimoto H, Miyajima N, Morimoto D, Mukoyama N, Nishikawa Y, Koide U, Kuwahara T, Kodera Y, Tanaka M, Kasuya H.
    • Organizer
      第23回日本遺伝子細胞治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] ヒト大腸がんモデルにおけるセツキシマブとの併用による腫瘍溶解性ウイルスHF10 の抗腫瘍効果2017

    • Author(s)
      呉 智聞, 一ノ瀬 亨, 駱 晨虹, 直江 吉則, イッツェル・ブストス・ビジャロボス, 山田 豪, 藤井 努, 杉本 博行, 森本 大士, 向山 宣昭, 小寺 泰弘, 田中 舞紀, 粕谷 英樹
    • Organizer
      第117 回日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] Clinical trial data using HF10, oncolytic herpes simplex virus2017

    • Author(s)
      Kasuya H, Ichinose T, Naoe Y, Villalobos I. B, Nassr E. I. R, Luo C, Zhiwen W, Mukoyama N, Miyajima N, Morimoto D, Hirooka Y, Goto H, Tanaka M.
    • Organizer
      第23回日本遺伝子細胞治療学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] Combination therapy of oncolytic herpes virus and anti-angiogenesis agent (bevacizumab) against human gastric cancer xenograft2017

    • Author(s)
      H. Kasuya, G. Tan, C. Luo, T. Ichinose, I. Bustos, Y. Naoe
    • Organizer
      EACR-AACR-SIC Special Conference 2017
    • Data Source
      KAKENHI-PROJECT-17K19696
  • [Presentation] マクロファージ分子M-modによる肥満症・糖尿病の制御2013

    • Author(s)
      北村 浩、木村俊介、嶋本良則、岡部 潤、宮本智美、直江吉則、岡本士毅、戸田知得、Assam El-Osta、三好一郎
    • Organizer
      第156回日本獣医学会学術集会
    • Place of Presentation
      岐阜大学(岐阜県)
    • Data Source
      KAKENHI-PROJECT-24500494
  • [Presentation] Cxxc5, ThPOK target gene, suppresses CD4+ helper T cell functions during CD8+cytotoxic T differentiation2013

    • Author(s)
      直江吉則、内藤拓、天野麻理、丸山光生、古関明彦、谷内一郎
    • Organizer
      第42回日本免疫学会
    • Place of Presentation
      千葉
    • Data Source
      KAKENHI-PROJECT-25460401
  • [Presentation] Possible involvement of a novel macrophage molecule in pathogenesis of type 2 diabetes2012

    • Author(s)
      Hiroshi Kitamura, Shunsuke Kimura, Tomomi Miyamoto, Masatoshi Ito, Yoshinori Shimamoto, Jun Okabe, Yoshinori Naoe, Koji Hase, Osamu Ohara, Ichiro Miyoshi
    • Organizer
      The 4th EMBO meeting
    • Place of Presentation
      アクロポリス国際会議場(ニース、フランス)
    • Data Source
      KAKENHI-PROJECT-24500494
  • [Presentation] ヘルパーT細胞分化過程における特異的な選択的スプライシングの検出2011

    • Author(s)
      直江吉則
    • Organizer
      第21回Kyoto T Cell Conference
    • Place of Presentation
      京都
    • Year and Date
      2011-06-11
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Presentation] 老化関連因子Zizimin2/Dock11の獲得免疫系における機能解析2011

    • Author(s)
      直江吉則
    • Organizer
      第34回日本基礎老化学会年会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-17
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Presentation] Functional analysis of an age-related novel GEF、Zizimin2/Dock11 in immunosenescence2011

    • Author(s)
      Naoe Y
    • Organizer
      Ninth Asia/Oceania Regional Congress of Gerontology and Geriatrics
    • Place of Presentation
      Melbourne、Australia
    • Year and Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Presentation] 加齢に伴う免疫低下メカニズムの解析2011

    • Author(s)
      直江吉則
    • Organizer
      第11回日本抗加齢医学会総会
    • Place of Presentation
      京都
    • Year and Date
      2011-05-28
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Presentation] Operationg with a fake ID at the border : Lineage switch of mucosal CD4T cells2010

    • Author(s)
      Naoe Y
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe、Japan
    • Year and Date
      2010-08-24
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Presentation] Molecular mechanisms of functional decline in the immunosenescence2010

    • Author(s)
      Naoe Y
    • Organizer
      Asian Aging Core for Longevity Research and Education 2010 Jeju Conference
    • Place of Presentation
      Jeju、Korea
    • Year and Date
      2010-08-23
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Presentation] 免疫老化関連因子Zizimin2/Dock11のin vivoにおける機能解析2010

    • Author(s)
      直江吉則
    • Organizer
      第33回日本基礎老化学会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-06-17
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Presentation] The zinc finger protein MAZR is part of the transcription factor network that regulates CD4/CD8 cell fate decision of DP thymocytes2010

    • Author(s)
      Naoe Y
    • Organizer
      14th International Congress of Immunology
    • Place of Presentation
      Kobe、Japan
    • Year and Date
      2010-08-25
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Presentation] Analysis of zizimin2 function in mouse dendritic cells2009

    • Author(s)
      Naoe Y
    • Organizer
      第32回分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-09
    • Data Source
      KAKENHI-PROJECT-21590348
  • [Presentation] マクロファージのUSP2による2型糖尿病制御の可能性

    • Author(s)
      北村 浩、木村俊介、宮本智美、岡部潤、嶋本良則、直江吉則、三好一郎
    • Organizer
      日本実験動物学会
    • Place of Presentation
      札幌コンベンションセンター(北海道)
    • Year and Date
      2014-05-15 – 2014-05-17
    • Data Source
      KAKENHI-PROJECT-24500494
  • [Presentation] マクロファージのUSP2-新たな糖尿病制御分子-

    • Author(s)
      北村浩、木村俊介、岡部潤、宮本智美、嶋本良則、直江吉則、戸田知得、岡本士毅、三好一郎
    • Organizer
      日本獣医学会
    • Place of Presentation
      北海道大学(北海道)
    • Year and Date
      2014-09-09 – 2014-09-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-24500494
  • 1.  粕谷 英樹 (00402636)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 31 results
  • 2.  松村 繁 (60523511)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 3.  ISHIDO Satoshi (10273781)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  KITAMURA Hiroshi (80312403)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 5.  MIYOSHI Ichiro (10183972)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 6.  OKAMOTO Shiki (40342919)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 7.  TAKAHASI Eiki (40446521)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  IWANAGA Toshihiko (10160128)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  KIMURA Shunsuke (40444525)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 10.  一ノ瀬 亨 (60778091)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 11.  SAKAUE Asako
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  KODERA Yasuhiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 13.  BUSTOS itzel
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 14.  EISSA ibrahim
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  竹下 淳
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  谷内 一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 17.  金井 昭教
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  稲葉 俊哉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  香城 諭
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  SEO WOOSEOK
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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