TANABE Hiroki 田邊裕貴

Researcher Number	50396363
Affiliation *help	2016 – 2018 : 旭川医科大学, 医学部, 講師 2011 – 2012 : 旭川医科大学, 医学部, 講師 2010 : 旭川医科大学, 医学部, 助教 2007 – 2008 : Asahikawa Medical College, 医学部, 助教 2007 : 旭川医科大学, 医学部, 特任助教
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator プロテオーム / 消化器学 / defensin / 生理活性 / 自然免疫 / 細胞・組織 / クローン病 / 移植・再生医療 / Paneth細胞 / DSS腸炎 / 再生医療 … More Except Principal Investigator … More

The development of therapy for inflammatory bal tissue with Paneth cell-protection factorsowel disease using cultured epitheliPrincipal Investigator
- Principal Investigator
  
  TANABE Hiroki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity start-up
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College
Analysis of the ER molecular chaperone in inflammatory bowel disease.
- Principal Investigator
  
  ITO Takahiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College
Development of a novel treatment for inflammatory bowel disease via the regulation of the bacteria recognition system and effective molecules derived from bacteria
- Principal Investigator
  
  KOHGO Yutaka
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College
The structure-activity relationship of prodefensin is investigated for a novel therapy of inflammatory bowel diseasePrincipal Investigator
- Principal Investigator
  
  TANABE Hiroki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College

All 2012 2010 2009 2008 2007 Other

All Journal Article Presentation Book

[Book] Trypsin: Structure, Biosynthesis Functions2012
- Author(s)
  Hiroki Tanabe
- Total Pages
  7
- Publisher
  Nova Scientific Publishers
- Data Source
  KAKENHI-PROJECT-23890012
[Book] Trypsin acts as an activating enzyme in Gut Innate Immunity2012
- Author(s)
  H Tanabe, M Fujiya, Y Kohgo
- Total Pages
  10
- Publisher
  NOVA publisher
- Data Source
  KAKENHI-PROJECT-23890012
[Book] Trypsin:Structure, Biosynthesis and Functions. Trypsin acts as an activating enzyme in gut innate immunity
- Author(s)
  Structure, Biosynthesis and Functions. Trypsin acts as an activating enzyme in gut innate immunity. Hiroki Tanabe, Mikihiro Fujiya and Yutaka Kohgo
- Publisher
  2012 Nova Scuentific Publishers, inc
- Data Source
  KAKENHI-PROJECT-23890012
[Journal Article] Collagenous colitis appeared after the 6-year administration of lansoprazole2010
- Author(s)
  Sawada K, Fujiya M, Itabashi K, Suzuki Y, Kubo K, Kashima S, Nomura Y, Nata T, Ueno N, Ishikawa C, Inaba Y, Itoh T, Moriichi K, Okamoto K, Ikuta K, Tanabe H, Mizukami Y, Kohgo Y.
- Journal Title
  
  Clin J Gastorol 3
  
  Pages : 18-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] Expression of the antimicrobial peptide alpha-defensin/cryptdins in intestinal crypts decreases at the initial phase of intestinal inflammation in a model of inflammatory bowel disease, IL-10-deficient mice.2010
- Author(s)
  Inaba Y, Ashida T, Ito T, Ishikawa C, Tanabe H, Maemoto A, Watari J, Ayabe T, Mizukami Y, Fujiya M, Kohgo Y
- Journal Title
  
  Inflamm Bowel Dis. 16
  
  Pages : 1488-1495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590733
[Journal Article] The expression of the anti-microbial peptide α-defensin/cryptdins in intestinal crypts decreases at the initial phase of intestinal inflammation in a model of inflammatory bowel disease, IL-10 deficient mice.2010
- Author(s)
  Inaba Y, Ashida T, Ito T, Ishikawa C, Tanabe H, Maemoto A, Watari J, Ayabe T, Mizukami Y, Fujiya M, Kohgo Y
- Journal Title
  
  Inflammatory Bowel Diseases 16(9)
  
  Pages : 1488-95
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] Precursor Processing of Human Defensin-5 Is Essential to the Multiple Functions in vitro and in vivo.2010
- Author(s)
  Ishikawa C, Tanabe H, Maemoto A, Ito T, Watari J, Kono T, Fujiya M, Ashida T, Ayabe T, Kohgo Y
- Journal Title
  
  J Innate Immunity 2
  
  Pages : 66-76
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] Precursor Processing of Human Defensin-5 Is Essential to the Multiple Functions in vitro and in vivo2010
- Author(s)
  Ishikawa C, Tanabe H, Maemoto A, Ito T, Watari J, Kono T, Fujiya M, Ashida T, Ayabe T, Kohgo Y.
- Journal Title
  
  J Innate Immunity 2
  
  Pages : 66-76
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] Effects of Helicobacter pylori infection on genetic instability, the aberrant CpG island methylation status and the cellular phenotype in Barrett's esophagus in a Japanese population2009
- Author(s)
  Moriichi K, Watari J, Das KM, Tanabe H, Fujiya M, Ashida T, Kohgo Y.
- Journal Title
  
  Int J Cancer 124
  
  Pages : 1263-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] 抗菌ペプチドによる消化管バリア療法の可能性は?2009
- Author(s)
  田邊裕貴, 伊藤貴博, ら
- Journal Title
  
  分子消化器病 6
  
  Pages : 133-139
- Data Source
  KAKENHI-PROJECT-20590733
[Journal Article] 抗菌ペプチドによる消化管バリア療法の可能性は?2009
- Author(s)
  田邊裕貴,伊藤貴博, ら
- Journal Title
  
  分子消化器病 6巻
  
  Pages : 133-139
- Data Source
  KAKENHI-PROJECT-20590733
[Journal Article] Precursor processing of human defensin-5 is essential to the multiple functions in vitro and in vivo.2009
- Author(s)
  Ishikawa C, Tanabe H, Maemoto A, Ito T, Watari J, Kono T, Fujiya M, Ashida T, Ayabe T, Kohgo Y
- Journal Title
  
  J Innate Immun. 2
  
  Pages : 66-76
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590733
[Journal Article] Functional Role of Metaplastic Paneth Cell Defensins in Helicobacter pylori- Infected Stomach2008
- Author(s)
  Hiroki Tanabe, Tomonobu Sato, Jiro Watari, Atsuo Maemoto, Mikihiko Fijiya, Toru Kono, Toshifumi Ashida, Tokiyoshi Ayabe, Yutaka Kohgo
- Journal Title
  
  Helicobacter 13
  
  Pages : 370-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590708
[Journal Article] Functional Role of Metaplastic Paneth Cell Defensins in Helicobacter pylori-Infected Stomach2008
- Author(s)
  Hiroki Tanabe, Tomonobu Sato,Jiro Watari, Atsuo Maemoto, Mikihiko Fijiya, Toru Kono, Toshifumi Ashida, Tokiyoshi Ayabe and Yutaka Kohgo
- Journal Title
  
  Helicobactor 13
  
  Pages : 370-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] Clinicopathological implications in genetic instability in intestinal type gastric cancer and intestinal metaplasia as a precancerous lesion : Proof of field cancerization in the stomach2008
- Author(s)
  Zaky A, Watari J, Tanabe H, Sato R, Moriichi K, Tanaka A, Maemoto A, Fujiya M, Ashida T, Kohgo Y.
- Journal Title
  
  Am J Clin Pathol 129(4)
  
  Pages : 613-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] Functional role of metaplastic paneth cell defensins in Helicobacter pylori-infected stomach.2008
- Author(s)
  Tanabe H, Sato T, Watari J, Maemoto A, Fijiya M, Kono T, Ashida T, Ayabe T, Kohgo Y
- Journal Title
  
  Helicobacter. 13
  
  Pages : 370-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590733
[Journal Article] Functional role of metaplastic paneth cell defensins in Helicobacter pylori-infected stomach.2008
- Author(s)
  Tanabe H, Maemoto A, Fijiya M, Ashida T, Kohgo Y
- Journal Title
  
  Helicobacter. 13(5)
  
  Pages : 70-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] Fnctional Role of Metaplastic Paneth Cell Defensins in Helicobacter pylori-Infected Stomach2008
- Author(s)
  Tanabe H
- Journal Title
  
  Helicobacter 13(5)
  
  Pages : 370-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590733
[Journal Article] Functional Role of Metaplastic Paneth Cell Defensins in Helicobacter pylori-Infected Stomach2008
- Author(s)
  Hiroki Tanabe
- Journal Title
  
  Helicobacter 13
  
  Pages : 370-379
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590708
[Journal Article] Denatured human alpha-defensin attenuates the bactericidal activity and the stability against enzymatic digestion.2007
- Author(s)
  Tanabe H, Ayabe T, Maemoto A, Ishikawa C, Inaba Y, Sato R, Moriichi K, Okamoto K, Watari J, Kono T, Ashida T, Kohgo Y.
- Journal Title
  
  Biochem Biophys Res Commun. 358(1)
  
  Pages : 349-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] クローン病におけるPaneth細胞由来抗菌ペプチドの産生異常2007
- Author(s)
  田邊裕貴, 前本篤男, 綾部時芳, 河野透, 蘆田知史, 高後裕
- Journal Title
  
  分子消化器病 4
  
  Pages : 110-115
- Data Source
  KAKENHI-PROJECT-19590708
[Journal Article] Denatured human alpha-defensin attenuates the bactericidal activity and the stability against enzymatic digestion2007
- Author(s)
  Tanabe H, Ayabe T, Maemoto A, Ishikawa C, Inaba Y, Sato R, Moriichi K, Okamoto K, Watari J, Kono T, Ashida T, Kohgo Y.
- Journal Title
  
  Biochem Biophys Res Commun. 358
  
  Pages : 349-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590708
[Journal Article] Denatured human alpha-defensin attenuates the bactericidal activity and the stability against enzymatic digestion.2007
- Author(s)
  Hiroki Tanabe
- Journal Title
  
  Biochem Biophys Res Commun 358
  
  Pages : 349-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590708
[Journal Article] Denatured human alpha-defensin attenuates the bactericidal activity and the stability against enzymatic digestion2007
- Author(s)
  Tanabe H, Ayabe T, Maemoto A, Ishikawa C, Inaba Y, Sato R, Moriichi K, Okamoto K, Watari J, Kono T, Ashida T, Kohgo Y.
- Journal Title
  
  Biochem Biophys Res Commun 358
  
  Pages : 349-355
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] Denatured human alpha-defensin attenuates the bactericidal activity and the stability against enzymatic digestion.2007
- Author(s)
  Tanabe H, Maemoto A, Ashida T, Kohgo Y
- Journal Title
  
  Biochem Biophys Res Commun. 358(1)
  
  Pages : 349-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] クローン病におけるPaneth細胞由来抗菌ペプチドの産生異常2007
- Author(s)
  田邊裕貴
- Journal Title
  
  分子消化器病 4
  
  Pages : 110-115
- Data Source
  KAKENHI-PROJECT-19590708
[Journal Article] Immunoprecipitation of nucleosomal DNA is a novel procedure to improve the sensitivity of serum screening for the p16 hypermethylation associated with colon cancer
- Author(s)
  Sakamoto J, Fujiya M, Okamoto K, Nata T, Inaba Y, Moriichi K, Tanabe H, Mizukami Y, Watari J, Ashida T, Kohgo Y.
- Journal Title
  
  Cancer Epidemiology (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] The expression of the anti-microbial peptide α-defensin/cryptdins in intestinal crypts decreases at the initial phase of intestinal inflammation in a model of inflammatory bowel disease, IL-10 deficient mice
- Author(s)
  Inaba Y, Ashida T, Ito T, Ishikawa C, Tanabe H, Maemoto A, Watari J, Ayabe T, Mizukami Y, Fujiya M, Kohgo Y.
- Journal Title
  
  Inflammatory Bowel Diseases (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390194
[Journal Article] Heat-killed body of Lactobacillus brevis SBC8803 ameliorates intestinal injury in a murine model of colitis by enhancing the intestinal barrier function.
- Author(s)
  Ueno N, Fujiya M, Segawa S, Nata T, Moriichi K, Tanabe H, Mizukami Y, Kobayashi N, Ito K, Kohgo Y
- Journal Title
  
  Inflammatory Bowel Diseases (in press)
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Competence and Sporulation Factor Derived From Bacillus Subtilis Improves Epithelial Cell Injury in Intestinal Inflammation via Immunomodulation and Cytoprotection2010
- Author(s)
  Okamoto K, Fujiya M, Nata T, Ueno N, Inaba Y, Ishikawa C, Ito T, Moriichi K, Tanabe H, Mizukami Y, Chang EB, Kohgo Y.
- Organizer
  DDW
- Place of Presentation
  New Orleans, USA.
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Heat killed Lactobaccilus brevis SBC8803 improves intestinal injury in a murine model of colitis via the enhancement of the intestinal barrier function and the down-regulation of pro-inflammatory cytokines.2010
- Author(s)
  Fujiya M, Ueno N, Segawa S, Nata T, Moriichi K, Tanabe H, Mizukami Y, Kobayashi N, Ito K, Kohgo Y
- Organizer
  The 4th Korea-Japan Inflammatory Bowel Disease Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2010-01-23
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Heat-Killed Body of Lactobacillus brevis SBC8803 Contributes to Maintain Intestinal Homeostasis and Improve Intestinal Injury in a Murine Model of Colitis.2010
- Author(s)
  Ueno N, Fujiya M, Segawa S, Nata T, Inaba Y, Moriichi K, Tanabe H, Mizukami Y, Kobayashi N, Ito K, Koheo Y
- Organizer
  DDW 2010 (AGA)
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-04
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Competence and Sporulation Factor Derived From Bacillus Subtilis Improves Epithelial Cell Injury in Intestinal Inflammation via Immunomodulation and Cytoprotection.2010
- Author(s)
  Okamoto K, Fujiva M, Nata T, Ueno N, Inaba Y, Ishikawa C, Ito T, Moriichi K, Tanabe H, Mizukami Y, Chang EB, Kohgo Y
- Place of Presentation
  New Orleans
- Year and Date
  2010-05-05
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Heat killed Lactobaccilus brevis SBC8803 improves intestinal injury in a murine model of colitis via the enhancement of the intestinal barrier function and the down-regulation of pro-inflammatory cytokines2010
- Author(s)
  Fujiya M, Ueno N, Segawa S, Nata T, Moriichi K, Tanabe H, Mizukami Y, Kobayashi N, Ito K, Kohgo Y.
- Organizer
  The 4th Korea-Japan Inflammatory Bowel Disease Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2010-01-23
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Infliximab may prevent post-operative recurrences in Crohn's disease2009
- Author(s)
  K.Okamoto, T.Ashida, R.Sugiyama, T.Nata, Y.Nomura, N.Ueno, C.Ishikawa, Y.Inaba, T.Ito, K.Moriihi, H.Tanabe, M.Fujiya, Y.Kohgo
- Organizer
  DDW 2009 (AGA)
- Place of Presentation
  Chicago
- Year and Date
  2009-06-01
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Precursor processing of human defensin-5 is essential to the physiological functions in vivo and in vitro2009
- Author(s)
  Hiroki Tanabe
- Organizer
  2009 International symposium on Regulatory Peptide
- Place of Presentation
  Santa Barbara, CA
- Year and Date
  2009-01-27
- Data Source
  KAKENHI-PROJECT-19590708
[Presentation] Precursor processing of human defensin-5 is essential to the physiological functions in vivo and in vitro2009
- Author(s)
  Tanabe H, Kohgo Y
- Organizer
  2009 International symposium on Regulatory Peptide
- Place of Presentation
  Tokyo
- Year and Date
  2009-01-27
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Heat killed Lactobacillus brevis SB8803 contributes to intestinal homeostasis via induction of heat shock proteins and activation of p38 mitogen -activated protein kinase2009
- Author(s)
  Ueno N, Fujiya M, Segawa S, Nata T, Inaba Y, Moriichi K, Tanabe H, Kohgo Y.
- Organizer
  Cell stress society international, 4th international conference
- Place of Presentation
  Sapporo
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Bacillus subtilis-produced pentapeptide csf contributes to intestinal homeostasis via octn2, a host cell membrane transporter2009
- Author(s)
  Fujiya M, Inaba Y, Nata T, Moriichi K, Okamoto K, Tanabe H, Mizukami Y, Chang EB, Kohgo Y.
- Organizer
  13th Taishotoyama International Symposium on Gastroenterology
- Place of Presentation
  Shimoda
- Year and Date
  2009-04-18
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Precursor processing of human defensin-5 is essential to the physiologic al functions in vivo and in vitro2009
- Author(s)
  Hiroki Tanabe
- Organizer
  International Symposium on Regulatory Peptide
- Place of Presentation
  Santa Barbara, CA
- Year and Date
  2009-01-27
- Data Source
  KAKENHI-PROJECT-19590708
[Presentation] ヒト大腸癌におけるα-defensin発現はMAPK阻害剤にて抑制される2008
- Author(s)
  田邊裕貴, 高後裕
- Organizer
  第95回北海道癌談話会
- Place of Presentation
  旭川
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] 腸管粘膜における抗菌ペプチドの役割2008
- Author(s)
  田邊裕貴
- Organizer
  平成20年度北海道腸内細菌叢研究会
- Place of Presentation
  札幌
- Year and Date
  2008-09-19
- Data Source
  KAKENHI-PROJECT-19590708
[Presentation] ヒト大腸癌におけるα-defensin発現はMAPK阻害剤にて抑制される2008
- Author(s)
  田邊裕貴
- Organizer
  第95回北海道癌談話会
- Place of Presentation
  旭川
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-19590708
[Presentation] 必須アミノ酸L-isoleucineはβ-defensin 2発現量を増加させる2008
- Author(s)
  金野陽高, 田邊裕貴, 前本篤男, 蘆田知史, 高後裕
- Organizer
  第50回日本消化器病学会
- Place of Presentation
  東京
- Year and Date
  2008-10-02
- Data Source
  KAKENHI-PROJECT-19590708
[Presentation] ヒト大腸癌におけるα-defensin発現はMAPK阻害剤にて抑制される2008
- Author(s)
  田邊裕貴, Zaky Amen, 石川千里, 上野伸展, 金野陽高, 稲場勇平, 伊藤貴博, 盛一健太郎, 岡本耕太郎, 藤谷幹浩, 高後裕
- Organizer
  第95回北海道癌談話会
- Place of Presentation
  旭川
- Year and Date
  2008-09-06
- Data Source
  KAKENHI-PROJECT-19590708
[Presentation] 腸管粘膜における抗菌ペプチドの役割2008
- Author(s)
  田邊裕貴, 藤谷幹浩, 高後裕
- Organizer
  平成20年度北海道腸内細菌叢研究会
- Place of Presentation
  札幌
- Year and Date
  2008-09-19
- Data Source
  KAKENHI-PROJECT-19590708
[Presentation] Effects of Helicobacter pylori Infection On Genetic Instability, Aberrant CpG Island Methylation Status and Cellular Phenotype in Intestinal Metaplasia of Barrett's Esophagus in Japanese Population : A Prospective Follow-Up Study After Eradication2008
- Author(s)
  Moriichi K, Tanabe H, Maemoto A, Fujiya M, Ashida T, Kohgo Y, et.al.
- Organizer
  DDW 2008 (AGA)
- Place of Presentation
  San Piego(米国)
- Year and Date
  2008-05-19
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] パネト細胞α-defensinと腸内自然免疫クローン病との関わりを含めて2008
- Author(s)
  綾部時芳, 深谷梨恵, 坂井直樹, 前本篤男, 蘆田知史, 河野透, 田邊裕貴, 高後裕
- Organizer
  第45回補体シンポジウム
- Place of Presentation
  札幌
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19590708
[Presentation] Human enteric defensin induces acquired immunity through activation processing2007
- Author(s)
  Hiroki Tanabe
- Organizer
  13th International Congress of Mucosal Immunology
- Place of Presentation
  Tokyo
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-19590708
[Presentation] Disruption of innate immunity in Crohn's disease2007
- Author(s)
  Atsuo Maemoto, Hiroki Tanabe, Yuhei Inaba, Takahiro Ito, Toshifumi Ashida, Tokiyoshi Ayabe, Yutaka Kohgo
- Organizer
  13th International Congress of Micosal Immunology 2007
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Human enteric defensin induces acquired immunity through activation processing2007
- Author(s)
  Hiroki Tanabe, Atsuo Maemoto, Tokiyoshi Ayabe, Toru Kono, Jiro Watari, Toshifumi Ashida, Yutaka Kogo
- Organizer
  13th International Congress of Mucosal Immunology 2007
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-19390194
[Presentation] Disruption of innate immunity in Crohn's disease2007
- Author(s)
  Maemoto A, Tanabe H, Inaba Y, Ito T, Ashida T, Ayabe T, Kohgo Y.
- Organizer
  13^<th> International Congress of Mucosal Immunology
- Place of Presentation
  Tokyo
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19590708
[Presentation] Down-regulation of Paneth cell a-defensin expression and function in patients with Crohn's disease2007
- Author(s)
  Maemoto A, Ayabe T, Tanabe H, Inaba Y, Ashida T, Fukaya R, Sakai N, Kono T, Kohgo Y.
- Organizer
  American Gastroenterological Association
- Place of Presentation
  Washington DC
- Year and Date
  2007-05-22
- Data Source
  KAKENHI-PROJECT-19590708
[Presentation] Human enteric defensin induces acquired immunity through activation processing2007
- Author(s)
  Tanabe H
- Organizer
  13^<th> International Congress of Mucosal Immunology
- Place of Presentation
  Tokyo
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19590708

1. KOHGO Yutaka (10133183)

# of Collaborated Projects : 1results

# of Collaborated Products : 26results
2. ASHIDA Toshifumi (50261409)

# of Collaborated Projects : 1results

# of Collaborated Products : 16results
3. FUJIYA Mikihiro (80322915)

# of Collaborated Projects : 1results

# of Collaborated Products : 17results
4. OHTAKE Takaaki (10359490)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
5. MAEMOTO Atsuo (40400113)

# of Collaborated Projects : 1results

# of Collaborated Products : 13results
6. ITO Takahiro (30396361)

# of Collaborated Projects : 1results

# of Collaborated Products : 4results

TANABE Hiroki 田邊 裕貴

Research Projects

Research Products

Co-Researchers

The development of therapy for inflammatory bal tissue with Paneth cell-protection factorsowel disease using cultured epitheliPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the ER molecular chaperone in inflammatory bowel disease.

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Development of a novel treatment for inflammatory bowel disease via the regulation of the bacteria recognition system and effective molecules derived from bacteria

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The structure-activity relationship of prodefensin is investigated for a novel therapy of inflammatory bowel diseasePrincipal Investigator

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[Book] Trypsin: Structure, Biosynthesis Functions2012

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[Book] Trypsin acts as an activating enzyme in Gut Innate Immunity2012

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[Book] Trypsin:Structure, Biosynthesis and Functions. Trypsin acts as an activating enzyme in gut innate immunity

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[Journal Article] Collagenous colitis appeared after the 6-year administration of lansoprazole2010

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[Journal Article] Expression of the antimicrobial peptide alpha-defensin/cryptdins in intestinal crypts decreases at the initial phase of intestinal inflammation in a model of inflammatory bowel disease, IL-10-deficient mice.2010

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[Journal Article] The expression of the anti-microbial peptide α-defensin/cryptdins in intestinal crypts decreases at the initial phase of intestinal inflammation in a model of inflammatory bowel disease, IL-10 deficient mice.2010

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[Journal Article] Precursor Processing of Human Defensin-5 Is Essential to the Multiple Functions in vitro and in vivo.2010

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[Journal Article] Precursor Processing of Human Defensin-5 Is Essential to the Multiple Functions in vitro and in vivo2010

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[Journal Article] Effects of Helicobacter pylori infection on genetic instability, the aberrant CpG island methylation status and the cellular phenotype in Barrett's esophagus in a Japanese population2009

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[Journal Article] 抗菌ペプチドによる消化管バリア療法の可能性は?2009

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[Journal Article] 抗菌ペプチドによる消化管バリア療法の可能性は?2009

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[Journal Article] Precursor processing of human defensin-5 is essential to the multiple functions in vitro and in vivo.2009

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[Journal Article] Functional Role of Metaplastic Paneth Cell Defensins in Helicobacter pylori- Infected Stomach2008

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TANABE Hiroki 田邊裕貴