HARA Noboru 原昇

Researcher Number	50397113
Affiliation *help	2016 – 2018 : 新潟大学, 医歯学総合病院, 講師 2009 – 2011 : Niigata University, 医歯学総合病院, 助教
Review Section/Research Field	Principal Investigator Urology
Keywords	Principal Investigator 分子機構 / アンドロゲン環境 / p27 / ATBF1 / 前立腺癌 / p21 / 予後診断 / DHEA-S / 内分泌療法

The association of intracellular localization and expression of ATBF1 with the malignant potential of prostate cancerPrincipal Investigator
- Principal Investigator
  
  HARA Noboru
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Urology
- Research Institution
  Niigata University

All 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Insulin-like growth factor-1 is associated with regulation of the luteinizing hormone production in men receiving androgen deprivation therapy with gonadotropin-releasing hormone analogues for localized prostate cancer2012
- Author(s)
  Hara N, Takizawa I, Isahaya E, Nishiyama T, Hoshii T, Ishizaki F, Takahashi K
- Journal Title
  
  Urologic Oncology : Seminars & Original investigations
- URL
  http://dx.doi.org/10.1016/j.urolonc.2010.11.001
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Prediction of pathological and oncological outcomes based on extended prostate biopsy results in patients with prostate cancer receiving radical prostatectomy : A single institution study2012
- Author(s)
  Ishizaki F, Hara N, et al.
- Journal Title
  
  Diagnostic Pathology
- URL
  http://www.diagnosticpathology.diagnomx.eu/vs/8790262771042628
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Deficiency in androgens and upregulation of insulin-like growth factor-1 are involved in high bone turnover in men receiving androgen deprivation therapy for prostate cancer2012
- Author(s)
  Ishizaki F, Hara N, Takizawa I, Nishiyama T, Isahaya E, Kawasaki T, Takahashi K
- Journal Title
  
  Growth Hormone & IGF Research
- URL
  http://dx.doi.org/10.1016/j.ghir.2012.04.003
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Prostate carcinogenesis with diabetes and androgen deprivation therapy-related diabetes : An update2012
- Author(s)
  Hara N
- Journal Title
  
  Experimental Diabetes Research
  
  Volume : (in press)
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Insulin-like growth factor-1 is associated with regulation of the luteinizing hormone production in men receiving androgen deprivation therapy with gonadotropin-releasjng hormone analogues for localized prostate cancer2012
- Author(s)
  原昇, 他
- Journal Title
  
  Urologic Oncology : Seminars and Original Investigations
  
  Volume : (In press)
- DOI
  10.1016/j.urolonc.2010.11.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] External Validation of the UCSF-CAPRA (University of California, San Francisco, Cancer of the Prostate Risk Assessment) in Japanese Patients Receiving Radical Prostatectomy2012
- Author(s)
  石崎文男、ホークアミヌイ、西山勉、川崎隆、笠原隆、原昇, 他
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume : 41 Pages : 1259-1264
- DOI
  10.1093/jjco/hyr136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493, KAKENHI-PROJECT-09F09353
[Journal Article] Altered association of interleukin-6 with sex steroids in lipid metabolism disorder in men with prostate cancer receiving androgen deprivation therapy.2012
- Author(s)
  小松集一、原昇, 他
- Journal Title
  
  Prostate.
  
  Volume : (In press) Pages : 1207-1213
- DOI
  10.1002/pros.22471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493, KAKENHI-PROJECT-24592380, KAKENHI-PROJECT-21592035
[Journal Article] Kattan postoperative nomogram for renal cell carcinoma : predictive accuracy in a Japanese population2011
- Author(s)
  鈴木一也、西山勉、原昇, 他
- Journal Title
  
  International Journal of Urology
  
  Volume : 18 Pages : 194-199
- DOI
  10.1111/j.1442-2042.2010.02693.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Clinical feature of men who benefit from dose escalation of naftopidil for lower urinary tract symptoms : a prospective study2011
- Author(s)
  水澤隆樹、原昇, 他
- Journal Title
  
  Advances in Urology
  
  Volume : 2011 Pages : 804583-804583
- DOI
  10.1155/2011/804583
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] External validation of the UCSF-CAPRA(University of California, San Francisco, Cancer of the Prostate Risk Assessment) in Japanese patients receiving radical prostatectomy2011
- Author(s)
  Ishizaki F, Hoque MA, Nishiyama T, Kawasaki T, Kasahara T, Hara N, Takizawa I, Saito T, Kitamura Y, Akazawa K, Takahashi K
- Journal Title
  
  Japanese Journal of Clinical Oncology
  
  Volume : 41(11) Pages : 1259-64
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Nephrectomy plus endoscopy-assisted intussusception ureterectomy for patients with renal pelvic cancer : long-term oncological outcomes in comparison with nephroureterectomy plus bladder cuff removal2011
- Author(s)
  原昇, 他
- Journal Title
  
  Journal of Endourology
  
  Volume : 25 Pages : 691-697
- DOI
  10.1089/end.2010.0336
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Nephrectomy plus endoscopy-assisted intussusception ureterectomy for patients with renal pelvic cancer : long-term oncological outcomes in comparison with nephroureterectomy plus bladder cuff removal2011
- Author(s)
  原昇, 他
- Journal Title
  
  Journal of Endourology
  
  Volume : (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Insulin-like growth fador-1 is associated with regulation of the luteinizing hormone production in men receiving androgen deprivation therapy with gonadotropin-releasing hormone analogues for localized prostate cancer2011
- Author(s)
  原昇, 他
- Journal Title
  
  Urologic Oncology : Seminars and Original Investigations
  
  Volume : (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Parathyroid hormone-related peptide-producing non-familial pheochromocytoma in a child.2010
- Author(s)
  武田啓、原昇, 他
- Journal Title
  
  International Journal of Urology
  
  Volume : 17 Pages : 673-676
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Mechanism of acute antibody-mediated rejection in ABO-incompatible kidney transplantation : which anti-A/anti-B antibodies are responsible, natural or de novo?2010
- Author(s)
  高橋公太、齊藤和英、中川由紀、田崎正之、原昇, 他
- Journal Title
  
  Transplantation
  
  Volume : 89 Pages : 635-637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Trilostane, an inhibitor of 3β-hydroxysteroid dehydrogenase, has an agonistic activity on androgen receptor in human prostate cancer cells2010
- Author(s)
  Takizawa I, Nishiyama T, Hara N, Hoshii T, Ishizaki F, Miyashiro Y, Takahashi K
- Journal Title
  
  Cancer Letter
  
  Volume : 297(2) Pages : 226-30
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Adrenocorticotropic hormone is involved in regulation of androgen synthesis in men receiving androgen deprivation therapy for localized prostate cancer2010
- Author(s)
  Takizawa I, Hara N, Nishiyama T, Isahaya E, Hoshii T, Takahashi K
- Journal Title
  
  The Journal of Urology
  
  Volume : 184(5) Pages : 1971-6
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Adrenocorticotropic hormone is involved in regulation of androgen synthesis in men receiving androgen deprivation therapy for localized prostate cancer.2010
- Author(s)
  瀧澤逸大、原昇, 他
- Journal Title
  
  The Journal of Urology
  
  Volume : 184 Pages : 1971-1976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Serum prostate-specific antigen levels reflect the androgen milieu in patients with localized prostate cancer receiving androgen deprivation therapy : Tumor malignant potential and androgen milieu.2010
- Author(s)
  瀧澤逸大、西山勉、原昇, 他
- Journal Title
  
  The Prostate
  
  Volume : 70 Pages : 1395-1401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Decline of the Red Blood Cell Count in Patients Receiving Androgen Deprivation Therapy for Localized Prostate Cancer : Impact of ADT on Insulin-like Growth Factor-1 and Erythropoiesis.2010
- Author(s)
  原昇, 他
- Journal Title
  
  Urology
  
  Volume : 75 Pages : 1441-1445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Bone metabolic disorder in patients with prostate cancer receiving androgen deprivation therapy (ADT) : impact of ADT on the growth hormone/insulin-like growth factor-1/parathyroid hormone axis.2010
- Author(s)
  伊佐早悦子、原昇, 他
- Journal Title
  
  The Prostate
  
  Volume : 70 Pages : 155-161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Bone metabolic disorder in patients with prostate cancer receiving androgen deprivation therapy(ADT): impact of ADT on the growth hormone/insulin-like growth factor-1/parathyroid hormone axis2010
- Author(s)
  Isahaya E, Hara N, Nishiyama T, Hoshii T, Takizawa I, Takahashi K
- Journal Title
  
  The Prostate
  
  Volume : 70(2) Pages : 155-61
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Serum prostate-specific antigen levels reflect the androgen milieu in patients with localized prostate cancer receiving androgen deprivation therapy : Tumor malignant potential and androgen milieu2010
- Author(s)
  Nishiyama T, Hara N, Isahaya E, Hoshii T, Takahashi K
- Journal Title
  
  Takizawa I, The Prostate
  
  Volume : 70(13) Pages : 1395-401
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Parathyroid hormone-related peptide-producing non-familial pheochromocytoma in a child2010
- Author(s)
  Takeda K, Hara N, Kawaguchi M, Nishiyama T, Takahashi K
- Journal Title
  
  International Journal of Urology
  
  Volume : 17(7) Pages : 673-6
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Decline of the red blood cell count in patients receiving androgen deprivation therapy for localized prostate cancer : impact of ADT on insulin-like growth factor-1 and erythropoiesis2010
- Author(s)
  Hara N, Nishiyama T, Takizawa I, Saito T, Kitamura Y, Takahashi K
- Journal Title
  
  Urology
  
  Volume : 75(6) Pages : 1441-5
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] RE : Decline of the red blood cell count in patients receiving androgen deprivation therapy for localized prostate cancer : impact of ADT on insulin-like growth factor-1 and erythropoiesis2010
- Author(s)
  Hara N
- Volume
  76
- Pages
  1021-1021
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Trilostane, an inhibitor of 3β-hydroxysteroid dehydrogenase, has an agonistic activity on androgen receptor in human prostate cancer cells.2010
- Author(s)
  瀧澤逸大、西山勉、原昇, 他
- Journal Title
  
  Cancer letter
  
  Volume : 297 Pages : 226-230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] RE : Decline of the red blood cell count in patients receiving androgen deprivation therapy for localized prostate cancer : impact of ADT on insulin-like growth factor-1 and erythropoiesis2010
- Author(s)
  原昇
- Journal Title
  
  Urology
  
  Volume : 76 Pages : 1021-1021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Journal Article] Decline of the Red Blood Cell Count in Patients Receiving Androgen Deprivation Therapy for Localized Prostate Cancer : Impact of ADT on Insulin-like Growth Factor-1 and Erythropoiesis.
- Author(s)
  Hara Noboru
- Journal Title
  
  Urology (現在on line)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] Associations Among Anabolic Endocrine Axes in Patients with Prostate Cancer Receiving Androgen Deprivation Therapy2011
- Author(s)
  原昇
- Organizer
  第31回国際泌尿器科学会
- Place of Presentation
  ドイツベルリン
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] アンドロゲン環境と血清PSA値及びグリーソンスコアとの関連2011
- Author(s)
  原昇
- Organizer
  第49回日本癌治療学会学術集会
- Place of Presentation
  名古屋市(招待講演)
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] アンドロゲン環境と血清PSA値及びグリーソンスコアとの関連2011
- Author(s)
  原昇
- Organizer
  第49回日本癌治療学会学術集会
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] Associations Among Anabolic Endocrine Axes in Patients with Prostate Cancer Receiving Androgen Deprivation Therapy2011
- Author(s)
  原昇
- Organizer
  第31回国際泌尿器科学会
- Place of Presentation
  ドイツ,ベルリン
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] Functional inactivation of insulin-like growth factor-1 in the bone may be relevant to osteoporosis during androgen deprivation therapy2010
- Author(s)
  原昇
- Organizer
  第25回欧州泌尿器科学会
- Place of Presentation
  スペインバルセロナ
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] Functional inactivation of insulin-like growth factor-1 in the bone maybe relevant to osteoporosis during androgen deprivation therapy2010
- Author(s)
  原昇
- Organizer
  第25回欧州泌尿器科学会
- Place of Presentation
  スペインバルセロナ
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] アンドロゲン除去療法による骨代謝障害: GH/IGF-1/PTH内分泌軸への影響2010
- Author(s)
  原昇
- Organizer
  第48回日本癌治療学会
- Place of Presentation
  京都市
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] アンドロゲン除去療法による骨代謝障害:成長ホルモン/インスリン様成長因子1(IGF-1)/副甲状腺ホルモン内分泌軸への影響2010
- Author(s)
  原昇
- Organizer
  第98回日本泌尿器科学会総会
- Place of Presentation
  盛岡市
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] アンドロゲン除去療法による骨代謝障害:GH/IGF-1/PTH内分泌軸への影響2010
- Author(s)
  原昇
- Organizer
  第48回日本癌治療学会
- Place of Presentation
  京都市
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] アンドロゲン除去療法による骨代謝障害:成長ホルモン/インスリン様成長因子1(IGF-1)/副甲状腺ホルモン内分泌軸への影響2010
- Author(s)
  原昇
- Organizer
  第98回日本泌尿器科学会総会
- Place of Presentation
  盛岡市
- Year and Date
  2010-04-27
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] Functional inactivation of insulin-like growth factor-1 in the bone may be relevant to osteoporosis during androgen deprivation therapy2010
- Author(s)
  原昇
- Organizer
  第25回欧州泌尿器科学会
- Place of Presentation
  スペイン,バルセロナ
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] 膀胱癌における転写因子ATBF1とp21(WAF1/CIP1)の発現:経過と予後の予測における有用性2009
- Author(s)
  原昇
- Organizer
  第97回日本泌尿器科学会総会
- Place of Presentation
  岡山
- Year and Date
  2009-04-16
- Data Source
  KAKENHI-PROJECT-21791493
[Presentation] Decline of the blood hemoglobin concentration in patients receiving androgen deprivation therapy (ADT) for prostate cancer : Impact of ADT on insulin-like growth factor-1 and erythropoiesis2009
- Author(s)
  原昇
- Organizer
  第30回国際泌尿器科学会
- Place of Presentation
  上海中国
- Year and Date
  2009-11-03
- Data Source
  KAKENHI-PROJECT-21791493

1. NISHIYAMA Tsutomu

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

HARA Noboru 原 昇

Research Projects

Research Products

Co-Researchers

The association of intracellular localization and expression of ATBF1 with the malignant potential of prostate cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Insulin-like growth factor-1 is associated with regulation of the luteinizing hormone production in men receiving androgen deprivation therapy with gonadotropin-releasing hormone analogues for localized prostate cancer2012

Author(s)

Journal Title

URL

Data Source

[Journal Article] Prediction of pathological and oncological outcomes based on extended prostate biopsy results in patients with prostate cancer receiving radical prostatectomy : A single institution study2012

Author(s)

Journal Title

URL

Data Source

[Journal Article] Deficiency in androgens and upregulation of insulin-like growth factor-1 are involved in high bone turnover in men receiving androgen deprivation therapy for prostate cancer2012

Author(s)

Journal Title

URL

Data Source

[Journal Article] Prostate carcinogenesis with diabetes and androgen deprivation therapy-related diabetes : An update2012

Author(s)

Journal Title

Data Source

[Journal Article] Insulin-like growth factor-1 is associated with regulation of the luteinizing hormone production in men receiving androgen deprivation therapy with gonadotropin-releasjng hormone analogues for localized prostate cancer2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] External Validation of the UCSF-CAPRA (University of California, San Francisco, Cancer of the Prostate Risk Assessment) in Japanese Patients Receiving Radical Prostatectomy2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Altered association of interleukin-6 with sex steroids in lipid metabolism disorder in men with prostate cancer receiving androgen deprivation therapy.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kattan postoperative nomogram for renal cell carcinoma : predictive accuracy in a Japanese population2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical feature of men who benefit from dose escalation of naftopidil for lower urinary tract symptoms : a prospective study2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] External validation of the UCSF-CAPRA(University of California, San Francisco, Cancer of the Prostate Risk Assessment) in Japanese patients receiving radical prostatectomy2011

Author(s)

Journal Title

Data Source

[Journal Article] Nephrectomy plus endoscopy-assisted intussusception ureterectomy for patients with renal pelvic cancer : long-term oncological outcomes in comparison with nephroureterectomy plus bladder cuff removal2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nephrectomy plus endoscopy-assisted intussusception ureterectomy for patients with renal pelvic cancer : long-term oncological outcomes in comparison with nephroureterectomy plus bladder cuff removal2011

Author(s)

Journal Title

Data Source

[Journal Article] Insulin-like growth fador-1 is associated with regulation of the luteinizing hormone production in men receiving androgen deprivation therapy with gonadotropin-releasing hormone analogues for localized prostate cancer2011

Author(s)

Journal Title

Data Source

[Journal Article] Parathyroid hormone-related peptide-producing non-familial pheochromocytoma in a child.2010

Author(s)

Journal Title

Data Source

[Journal Article] Mechanism of acute antibody-mediated rejection in ABO-incompatible kidney transplantation : which anti-A/anti-B antibodies are responsible, natural or de novo?2010

Author(s)

Journal Title

Data Source

[Journal Article] Trilostane, an inhibitor of 3β-hydroxysteroid dehydrogenase, has an agonistic activity on androgen receptor in human prostate cancer cells2010

HARA Noboru 原昇