MIYATA KEISHI 宮田敬士

… Alternative Names

MIYATA Keishi 宮田敬士

宮田敬士ミヤタケイシ

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Researcher Number	50398228
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(医), 客員教授
Affiliation (based on the past Project Information) *help	2025: 熊本大学, 大学院生命科学研究部(医), 客員教授 2023: 熊本大学, 大学院生命科学研究部(医), 特別研究員 2021 – 2022: 熊本大学, 大学院生命科学研究部(医), 客員教授 2018 – 2020: 熊本大学, 大学院生命科学研究部(医), 特任准教授 2017: 熊本大学, その他の研究科, その他 … More 2017: 熊本大学, 大学院・生命科学研究部・免疫アレルギー血管病態学寄附講座, 特任准教授 2016: 熊本大学, 大学院生命科学研究部(医), 特任准教授 2015: 熊本大学, その他の研究科, 准教授 2015: 熊本大学, 大学院生命科学研究部, 特任准教授 2015: 熊本大学, 生命科学研究部, 特任准教授 2014: 熊本大学, 大学院生命科学研究部(医)医), 准教授 2014: 熊本大学, 大学院生命科学研究部・免疫アレルギー血管病態学寄附講座, 特任准教授 2013: 熊本大学, 生命科学研究部, 准教授 2013: 熊本大学, 生命科学研究部, 特任准教授 2011: 熊本大学, 大学院・生命科学研究部, 特任准教授 2011: 熊本大学, 生命科学研究部, 特任准教授 2010: 熊本大学, 生命科学研究部, 助教 2006 – 2007: 熊本大学, 発生医学研究センター, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine / Drug development chemistry / Circulatory organs internal medicine Except Principal Investigator Cardiovascular medicine / Neurosurgery
Keywords	Principal Investigator 心不全 / 鉄代謝 / SGLT2阻害薬 / DNA損傷応答 / マイクロRNA / 運動負荷 / miR-222 / miR-221 / 運動 / non-cording RNA … More / non-coding RNA / アンジオポエチン様因子 / メタボリックシンドローム / 生理活性 / マクロファージ / 循環器・高血圧 / 動脈硬化 … More Except Principal Investigator 慢性炎症 / 大動脈瘤 / アンジオポエチン様タンパク質２ / Angptl2 / 動脈硬化 / 腹部大動脈瘤 / 脳動脈瘤 / angptl2 / 動脈瘤 Less

SGLT２阻害薬長期投与による心筋細胞内鉄動態・代謝の変容と心機能への影響の検討Principal Investigator
- Principal Investigator
  
  宮田敬士
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kumamoto University
「鉄」を標的とした心不全病態解明と新規治療戦略Principal Investigator
- Principal Investigator
  
  宮田敬士
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kumamoto University
Elucidation of novel molecular mechanisms of the treatment strategy for heart failure by inactivating the DNA damage responsePrincipal Investigator
- Principal Investigator
  
  Miyata Keishi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kumamoto University
Mechanism of arteriosclerosis targeting chronic inflammation and possibility of new drug treatment
- Principal Investigator
  
  Kawano Takayuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kurume University
  Kumamoto University
The role of microRNA in molecular mechanism of heart failure developmentPrincipal Investigator
- Principal Investigator
  
  Miyata Keishi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kumamoto University
The discovery of a new predictor of aortic aneurysm rupture
- Principal Investigator
  
  Tazume Hirokazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kumamoto University
The role of long non-cording RNA in pathological mechanism of heart failure.Principal Investigator
- Principal Investigator
  
  MIYATA KEISHI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kumamoto University
The basic research for the relationship of chronic inflammation and pathogenesis of cerebral aneurysm
- Principal Investigator
  
  Kawano Takayuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kumamoto University
The discovery of a new predictor of aortic aneurysm rupture
- Principal Investigator
  
  TAZUME Hirokazu
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kumamoto University
Molecular and functional analysis of bioactive factor AGF in biological control systemPrincipal Investigator
- Principal Investigator
  
  MIYATA Keishi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kumamoto University
血管におけるAbhd2遺伝子の機能解析Principal Investigator
- Principal Investigator
  
  宮田敬士
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kumamoto University

[Journal Article] Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy2024
- Author(s)
  Horiguchi Haruki、Kadomatsu Tsuyoshi、Yamashita Tomoya、Yumoto Shinsei、Horino Taichi、Sato Michio、Terada Kazutoyo、Miyata Keishi、Ichigozaki Yuki、Kimura Toshihiro、Fukushima Satoshi、Moroishi Toshiro、Oike Yuichi
- Journal Title
  
  Cancer Gene Therapy
  
  Volume: Online ahead of print Issue: 6 Pages: 0-0
- DOI
  10.1038/s41417-024-00757-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16285, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-23K06638, KAKENHI-PROJECT-23K07511, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-21H04825
[Journal Article] Fasudil inhibits the expression of C/EBP homologous protein to protect against liver injury in acetaminophen-overdosed mice2023
- Author(s)
  Namba Nanami、Kuwahara Takehiro、Kondo Yuki、Fukusaki Kumiko、Miyata Keishi、Oike Yuichi、Irie Tetsumi、Ishitsuka Yoichi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 686 Pages: 149166-149166
- DOI
  10.1016/j.bbrc.2023.149166
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-21H04825
[Journal Article] ANGPTL2‐mediated epigenetic repression of MHC‐I in tumor cells accelerates tumor immune evasion2023
- Author(s)
  Kadomatsu Tsuyoshi、Hara Chiaki、Kurahashi Ryoma、Horiguchi Haruki、Morinaga Jun、Miyata Keishi、Kurano Sohtaro、Kanemaru Hisashi、Fukushima Satoshi、Araki Kimi、Baba Masaya、Linehan W. Marston、Kamba Tomomi、Oike Yuichi
- Journal Title
  
  Molecular Oncology
  
  Volume: 17 Issue: 12 Pages: 2637-2658
- DOI
  10.1002/1878-0261.13490
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-23K06638, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-21K08351, KAKENHI-PROJECT-21K19721, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-20K16450, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-23K24474
[Journal Article] Steep increase in the number of transthyretin-positive cardiac biopsy cases in Japan: evidence obtained by the nation-wide pathology consultation for the typing diagnosis of amyloidosis2023
- Author(s)
  Naiki H, Yamaguchi A, Sekijima Y, Ueda M, Ohashi K, Hatakeyama K, Ikeda Y, Hoshii Y, Shintani-Domoto Y, Miyagawa-Hayashino A, Tsujikawa H, Endo J, Arai T, Ando Y.
- Journal Title
  
  Amyloid
  
  Volume: 30 Issue: 1 Pages: 321-326
- DOI
  10.1038/s42003-023-04680-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07528, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-23K21370
[Journal Article] Efficacy and safety in mice of repeated, lifelong administration of an ANGPTL3 vaccine2023
- Author(s)
  Fukami Hirotaka、Morinaga Jun、Nakagami Hironori、Hayashi Hiroki、Okadome Yusuke、Matsunaga Eiji、Kadomatsu Tsuyoshi、Horiguchi Haruki、Sato Michio、Sugizaki Taichi、Miyata Keishi、Torigoe Daisuke、Mukoyama Masashi、Morishita Ryuichi、Oike Yuichi
- Journal Title
  
  npj Vaccines
  
  Volume: 8 Issue: 1 Pages: 168-168
- DOI
  10.1038/s41541-023-00770-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-22K11727, KAKENHI-PROJECT-23K07511, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-22K16429, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-21H02827
[Journal Article] ANGPTL2 promotes immune checkpoint inhibitor-related murine autoimmune myocarditis2023
- Author(s)
  Horiguchi Haruki、Kadomatsu Tsuyoshi、Yamashita Tomoya、Yumoto Shinsei、Terada Kazutoyo、Sato Michio、Morinaga Jun、Miyata Keishi、Oike Yuichi
- Journal Title
  
  Communications Biology
  
  Volume: 6 Issue: 1 Pages: 965-965
- DOI
  10.1038/s42003-023-05338-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-23K06638, KAKENHI-PROJECT-23K07511, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-21H04825
[Journal Article] Plasma ANGPTL8 Levels and Risk for Secondary Cardiovascular Events in Japanese Patients With Stable Coronary Artery Disease Receiving Statin Therapy2023
- Author(s)
  Morinaga Jun、Mukoyama Masashi、Oike Yuichi、et al.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 43 Issue: 8 Pages: 1549-1559
- DOI
  10.1161/atvbaha.122.318880
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18291, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-22K11727, KAKENHI-PROJECT-23K07511, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-22K16429, KAKENHI-PROJECT-21H04825
[Journal Article] Tumor cell-derived ANGPTL2 promotes β-catenin-driven intestinal tumorigenesis.2022
- Author(s)
  1.Horiguchi H, Kadomatsu T, Yumoto S, Masuda T, Miyata K, Yamamura S, Sato M, Morinaga J, Ohtsuki S, Baba H, Moroishi T, and Oike Y
- Journal Title
  
  Oncogene
  
  Volume: 41 Issue: 33 Pages: 4208-4041
- DOI
  10.1038/s41388-022-02405-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-21K15508, KAKENHI-PROJECT-21K16061
[Journal Article] A circulating subset of iNKT cells mediates antitumor and antiviral immunity2022
- Author(s)
  Cui G, Shimba A, et.al
- Journal Title
  
  Science Immunology
  
  Volume: 7 Issue: 76 Pages: 8760-8760
- DOI
  10.1126/sciimmunol.abj8760
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07545, KAKENHI-PROJECT-22K07086, KAKENHI-PROJECT-22K07133, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-20K21522, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-20K17580, KAKENHI-PROJECT-20H03501, KAKENHI-PROJECT-21J15058
[Journal Article] SIRT7 suppresses energy expenditure and thermogenesis by regulating brown adipose tissue functions in mice2022
- Author(s)
  Yoshizawa Tatsuya、Sato Yoshifumi、Sobuz Shihab U.、Mizumoto Tomoya、Tsuyama Tomonori、Karim Md. Fazlul、Miyata Keishi、Tasaki Masayoshi、Yamazaki Masaya、Kariba Yuichi、Araki Norie、Araki Eiichi、Kajimura Shingo、Oike Yuichi、Braun Thomas、Bober Eva、Auwerx Johan、Yamagata Kazuya
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 7439-7439
- DOI
  10.1038/s41467-022-35219-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08533, KAKENHI-PROJECT-22K08187, KAKENHI-PROJECT-22K08658, KAKENHI-PROJECT-22K19533, KAKENHI-PROJECT-22K16399, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H04107, KAKENHI-PROJECT-23K24388, KAKENHI-PROJECT-19H03772, KAKENHI-PROJECT-22F22111
[Journal Article] Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia2021
- Author(s)
  Fukami Hirotaka、Morinaga Jun、Nakagami Hironori、Hayashi Hiroki、Okadome Yusuke、Matsunaga Eiji、Kadomatsu Tsuyoshi、Horiguchi Haruki、Sato Michio、Sugizaki Taichi、Kuwabara Takashige、Miyata Keishi、Mukoyama Masashi、Morishita Ryuichi、Oike Yuichi
- Journal Title
  
  Cell Reports Medicine
  
  Volume: 2 Issue: 11 Pages: 100446-100446
- DOI
  10.1016/j.xcrm.2021.100446
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-20K17288, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-21K15508, KAKENHI-PROJECT-21K16061, KAKENHI-PROJECT-21K20935
[Journal Article] Hyperglycemia and Thrombocytopenia　― Combinatorially Increase the Risk of Mortality in Patients With Acute Myocardial Infarction Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation ―2021
- Author(s)
  Okadome Yusuke、Morinaga Jun、Fukami Hirotaka、Hori Kota、Ito Teruhiko、Sato Michio、Miyata Keishi、Kuwabara Takashige、Mukoyama Masashi、Suzuki Ryusuke、Tsunoda Ryusuke、Oike Yuichi
- Journal Title
  
  Circulation Reports
  
  Volume: 3 Issue: 12 Pages: 707-715
- DOI
  10.1253/circrep.CR-21-0043
- NAID
  130008128243
- ISSN
  2434-0790
- Year and Date
  2021-12-10
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-20K17288, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-21K16061, KAKENHI-PROJECT-21K20935
[Journal Article] The lncRNA Caren antagonizes heart failure by inactivating DNA damage response and activating mitochondrial biogenesis2021
- Author(s)
  Sato Michio, Kadomatsu Tsuyoshi, Miyata Keishi, Warren Junco S., Tian Zhe、Node Koichi、Araki Kimi、 Oike Yuichi et al
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 2529-2529
- DOI
  10.1038/s41467-021-22735-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-21K05999, KAKENHI-PROJECT-21K07101, KAKENHI-PROJECT-21K15508, KAKENHI-PROJECT-21K16061, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-21H05274
[Journal Article] Melinjo seed extract increases adiponectin multimerization in physiological and pathological conditions.2020
- Author(s)
  K. Oniki, T. Kawakami, A. Nakashima, K. Miyata, T. Watanabe, H. Fujikawa, R. Nakashima, A. Nasu, Y. Eto, N. Takahashi, H. Nohara, M. Ann Suico, S. Kotani, Y. Obata, Y. Sakamoto, Y. Seguchi, J. Saruwatari, T. Imafuku, H. Watanabe, T. Maruyama, H. Kai, T. Shuto
- Journal Title
  
  Scientific reports
  
  Volume: 10 Issue: 1 Pages: 4313-4313
- DOI
  10.1038/s41598-020-61148-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06997, KAKENHI-PROJECT-19K07166, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-17H03570, KAKENHI-PROJECT-19H03379, KAKENHI-PROJECT-17K08309
[Journal Article] Circulating angiopoietin-like protein 2 levels and arterial stiffness in patients receiving maintenance hemodialysis: A cross-sectional study.2020
- Author(s)
  Fukami H, Morinaga J, Okadome Y, Nishiguchi Y, Iwata Y, Kanki T, Nakagawa T, Izumi Y, Kakizoe Y, Kuwabara T, Horiguchi H, Sato M, Kadomatsu T, Miyata K, Tajiri T, Oike Y, Mukoyama M.
- Journal Title
  
  Atherosclerosis.
  
  Volume: 315 Pages: 18-23
- DOI
  10.1016/j.atherosclerosis.2020.10.890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-20K08611, KAKENHI-PROJECT-20K17288, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-18K08247, KAKENHI-PROJECT-19K17607
[Journal Article] Stroma-derived ANGPTL2 establishes an anti-tumor microenvironment during intestinal tumorigenesis2020
- Author(s)
  Horiguchi Haruki、Kadomatsu Tsuyoshi、Miyata Keishi、Terada Kazutoyo、Sato Michio、Torigoe Daisuke、Morinaga Jun、Moroishi Toshiro、Oike Yuichi
- Journal Title
  
  Oncogene
  
  Volume: 40 Issue: 1 Pages: 55-67
- DOI
  10.1038/s41388-020-01505-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-18K07236, KAKENHI-PROJECT-19K17607, KAKENHI-PROJECT-21H04825, KAKENHI-PROJECT-21K07101
[Journal Article] Febuxostat, a Xanthine Oxidase Inhibitor, Decreased Macrophage Matrix Metalloproteinase Expression in Hypoxia.2020
- Author(s)
  Wei S, Isagawa T, Eguchi M, Sato D, Tsukano H, Miyata K, Oike Y, Takeda N, Ikeda S, Kawano H, Maemura K.
- Journal Title
  
  Biomedicines.
  
  Volume: 8(11) Issue: 11 Pages: 470-470
- DOI
  10.3390/biomedicines8110470
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K08542
[Journal Article] Aging- and obesity-related peri-muscular adipose tissue accelerates muscle atrophy2019
- Author(s)
  Zhu Shunshun、Tian Zhe、Torigoe Daisuke、Zhao Jiabin、Xie Peiyu、Sugizaki Taichi、Sato Michio、Horiguchi Haruki、Terada Kazutoyo、Kadomatsu Tsuyoshi、Miyata Keishi、Oike Yuichi
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 8 Pages: e0221366-e0221366
- DOI
  10.1371/journal.pone.0221366
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K17607, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-18K19519
[Journal Article] Loss of Endogenous HMGB2 Promotes Cardiac Dysfunction and Pressure Overload-Induced Heart Failure in Mice2019
- Author(s)
  Sato M, Miyata K, Tian Z, Kadomatsu T, Ujihara Y, Morinaga J, Horiguchi H, Endo M, Zhao J, Zhu S, Sugizaki T, Igata K, Muramatsu M, Minami T, Ito T, Bianchi ME, Mohri S, Araki K, Node K, Oike Y
- Journal Title
  
  Circ J
  
  Volume: 83 Issue: 2 Pages: 368-378
- DOI
  10.1253/circj.CJ-18-0925
- NAID
  130007557092
- ISSN
  1346-9843, 1347-4820
- Year and Date
  2019-01-25
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-18K15246, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-18H02904, KAKENHI-PROJECT-17H04740, KAKENHI-PROJECT-16K07093, KAKENHI-PROJECT-16K09504, KAKENHI-PROJECT-17K15622, KAKENHI-PROJECT-18KT0026, KAKENHI-PROJECT-19K17607, KAKENHI-PUBLICLY-19H04972, KAKENHI-PROJECT-17H03580, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18K19519
[Journal Article] Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity.2019
- Author(s)
  Horiguchi H, Kadomatsu T, Kurahashi R, Hara C, Miyata K, Baba M, Osumi H, Terada K, Araki K, Takai T, Kamba T, Linehan WM, Moroishi T, Oike Y.
- Journal Title
  
  Genes Dev
  
  Volume: 33 Issue: 23-24 Pages: 1641-1656
- DOI
  10.1101/gad.329417.119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07236, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-18H02438, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-18K19619, KAKENHI-PROJECT-18K15246
[Journal Article] Circulating angiopoietin-like protein 2 levels and mortality risk in patients receiving maintenance hemodialysis: a prospective cohort study2019
- Author(s)
  Morinaga J, Kakuma T, Fukami H, Hayata M, Uchimura K, Mizumoto T, Kakizoe Y, Miyoshi T, Shiraishi N, Adachi M, Izumi Y, Kuwabara T, Okadome Y, Sato M, Horiguchi H, Sugizaki T, Kadomatsu T, Miyata K, Tajiri S, Tajiri T, Tomita K, Kitamura K, Oike Y, Mukoyama M.
- Journal Title
  
  Nephrology Dialysis Transplantation
  
  Volume: 印刷中 Issue: 5 Pages: 854-860
- DOI
  10.1093/ndt/gfz236
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08247, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-19K08728, KAKENHI-PROJECT-19K17607, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-17K09704, KAKENHI-PROJECT-17K09705, KAKENHI-PROJECT-17K09706, KAKENHI-PROJECT-19K08729, KAKENHI-PROJECT-20K08611
[Journal Article] MiR-204-5p: a novel candidate urinary biomarker of Xp11.2 translocation renal cell carcinoma.2019
- Author(s)
  Kurahashi R, Kadomatsu T, Baba M, Hara C, Itoh H, Miyata K, Endo M, Morinaga J, Terada K, Araki K, Eto M, Schmidt LS, Kamba T, Linehan WM, Oike Y.
- Journal Title
  
  Cancer Science
  
  Volume: 印刷中 Issue: 6 Pages: 1897-1908
- DOI
  10.1111/cas.14026
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19619, KAKENHI-PROJECT-18H02938, KAKENHI-PROJECT-18K07236, KAKENHI-PROJECT-19K08560, KAKENHI-PROJECT-18H02809, KAKENHI-PROJECT-17K08663, KAKENHI-PROJECT-18K19519
[Journal Article] Age-dependent increase in angiopoietin-like protein 2 accelerates skeletal muscle loss in mice.2018
- Author(s)
  Zhao J, Tian Z, Kadomatsu T, Xie P, Miyata K, Sugizaki T, Endo M, Zhu S, Fan H, Horiguchi H, Morinaga J, Terada K, Yoshizawa T, Yamagata K, Oike Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 293 Issue: 5 Pages: 1596-1609
- DOI
  10.1074/jbc.m117.814996
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08663, KAKENHI-PUBLICLY-17H05652, KAKENHI-PROJECT-16H05328, KAKENHI-PROJECT-17F17121, KAKENHI-PROJECT-16K09504, KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-16K15445, KAKENHI-PROJECT-18K19519
[Journal Article] Angiopoietin-like protein 2 increases renal fibrosis by accelerating transforming growth factor-β signaling in chronic kidney disease.2016
- Author(s)
  Jun Morinaga, Tsuyoshi Kadomatsu, Keishi Miyata, Motoyoshi Endo, Kazutoyo Terada, Zhe Tian, Taichi Sugizaki, Hiroki Tanigawa, Jiabin Zhao, Shunshun Zhu, Michio Sato, Kimi Araki, Ken-ichi Iyama, Kengo Tomita, Masashi Mukoyama, Kimio Tomita, Kenichiro Kitamura, Yuichi Oike
- Journal Title
  
  Kidney International
  
  Volume: 89 Issue: 2 Pages: 327-341
- DOI
  10.1016/j.kint.2015.12.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-15K09031, KAKENHI-PROJECT-26461226, KAKENHI-PUBLICLY-15H01520, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-26860639, KAKENHI-PROJECT-26861112, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-26670405
[Journal Article] Glutathione S-transferase K1 genotype and overweight status in schizophrenia patients: A pilot study.2016
- Author(s)
  Oniki K, Kamihashi R, Tomita T, Ishioka M, Yoshimori Y, Osaki N, Tsuchimine S, Sugawara N, Kajiwara A, Morita K, Miyata K, Otake K, Nakagawa K, Ogata Y, Saruwatari J, Yasui-Furukori N.
- Journal Title
  
  Psychiatry Res.
  
  Volume: 239 Pages: 190-195
- DOI
  10.1016/j.psychres.2016.03.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26360049, KAKENHI-PROJECT-15K18925, KAKENHI-PROJECT-25860117, KAKENHI-PROJECT-15H04754, KAKENHI-PROJECT-26350872, KAKENHI-PROJECT-15K19239, KAKENHI-PROJECT-25461114
[Journal Article] ANGPTL2 activity in cardiac pathologies accelerates heart failure by perturbing cardiac function and energy metabolism.2016
- Author(s)
  Tian Z, Miyata K, Kadomatsu T, Horiguchi H, Fukushima H, Tohyama S, Ujihara Y, Okumura T, Yamaguchi S, Zhao J, Endo M, Morinaga J, Sato M, Sugizaki T, Zhu S, Terada K, Sakaguchi H, Komohara Y, Takeya M, Takeda N, Araki K, Manabe I, Fukuda K, Otsu K, Wada J, Murohara T, Mohri S, Yamashita JK, Sano M, Oike Y.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 13016-13016
- DOI
  10.1038/ncomms13016
- NAID
  120006345014
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01520, KAKENHI-PROJECT-15H06508, KAKENHI-PROJECT-26282127, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26293218, KAKENHI-PROJECT-16K09504, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-15K06836, KAKENHI-PROJECT-16K15445
[Journal Article] ANGPTL2 increases bone metastasis of breast cancer cells through enhancing CXCR4 signaling.2015
- Author(s)
  Masuda T, Endo M, Yamamoto Y, Odagiri H, Kadomatsu T, Nakamura T, Tanoue H, Ito H, Yugami M, Miyata K, Morinaga J, Horiguchi H, Motokawa I, Terada K, Morioka MS, Manabe I, Iwase H, Mizuta H, Oike Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 5 Issue: 1 Pages: 9170-9170
- DOI
  10.1038/srep09170
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
[Journal Article] Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans.2015
- Author(s)
  Wei FY, Zhou B, Suzuki T, Miyata K, Ujihara Y, Horiguchi H, Takahashi N, Xie P, Michiue H, Fujimura A, Kaitsuka T, Matsui H, Koga Y, Mohri S, Suzuki T, Oike Y, Tomizawa K.
- Journal Title
  
  Cell Metab
  
  Volume: 21 Issue: 3 Pages: 413-6
- DOI
  10.1016/j.cmet.2015.01.019
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390293, KAKENHI-PROJECT-24791502, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461571, KAKENHI-PROJECT-25620125, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26220205, KAKENHI-PROJECT-26282127, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26560442, KAKENHI-PROJECT-26670284, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26702035, KAKENHI-PROJECT-15K08178, KAKENHI-PLANNED-26113003
[Journal Article] The exacerbating roles of CCAAT/enhancer-binding protein homologous protein (CHOP) in the development of bleomycin-induced pulmonary fibrosis and the preventive effects of tauroursodeoxycholic acid (TUDCA) against pulmonary fibrosis in mice.2015
- Author(s)
  Tanaka Y, Ishitsuka Y, Hayasaka M, Yamada Y, Miyata K, Endo M, Kondo Y, Moriuchi H, Irikura M, Tanaka K, Mizushima T, Oike Y, Irie T.
- Journal Title
  
  Pharmacol Res.
  
  Volume: 99 Pages: 52-62
- DOI
  10.1016/j.phrs.2015.05.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460104, KAKENHI-PUBLICLY-15H01520, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-26670405
[Journal Article] A Muscle-liver-fat signaling axis is essential for central control of adaptive adipose remodeling2015
- Author(s)
  Shimizu N, Maruyama T, Yoshikawa N, Matsumiya R, Ma Y, Ito N, Tasaka Y, Kuribara-Souta A, Miyata K, Oike Y, Berger S, Schutz G, Takeda S & Tanaka H
- Journal Title
  
  Nat Commun
  
  Volume: - Issue: 1 Pages: 6693-6693
- DOI
  10.1038/ncomms7693
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390236, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26461375, KAKENHI-PROJECT-15K12695, KAKENHI-PROJECT-15K19018, KAKENHI-PROJECT-15J11847, KAKENHI-PROJECT-25461469, KAKENHI-PROJECT-25282202, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-26670405
[Journal Article] IRAP deficiency attenuates diet-induced obesity in mice through increased energy expenditure.2015
- Author(s)
  Niwa M, Numaguchi Y, Ishii M, Kuwahata T, Kondo M, Shibata R, Miyata K, Oike Y, Murohara T.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 457(1) Issue: 1 Pages: 12-8
- DOI
  10.1016/j.bbrc.2014.12.071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25860595, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-15K11169
[Journal Article] Tinea nigra showing a parallel ridge pattern on dermoscopy.2015
- Author(s)
  Noguchi H, Hiruma M, Inoue Y, Miyata K, Tanaka M, Ihn H.
- Journal Title
  
  J Dermatol.
  
  Volume: 42(5) Issue: 5 Pages: 518-520
- DOI
  10.1111/1346-8138.12830
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461114
[Journal Article] The adipocyte-inducible secreted phospholipases PLA2G5 and PLA2G2E play distinct roles in obesity.2014
- Author(s)
  Sato H, Taketomi Y, Ushida A, Isogai Y, Kojima T, Hirabayashi T, Miki Y, Yamamoto K, Nishito Y, Kobayashi T, Ikeda K, Taguchi R, Hara S, Ida S, Miyamoto Y, Watanabe M, Baba H, Miyata K, Oike Y, Gelb MH, Murakami M.
- Journal Title
  
  Cell Metab.
  
  Volume: 20 Issue: 1 Pages: 119-132
- DOI
  10.1016/j.cmet.2014.05.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116005, KAKENHI-PROJECT-24390021, KAKENHI-PROJECT-24619007, KAKENHI-PUBLICLY-25116720, KAKENHI-PROJECT-25460087, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25504004, KAKENHI-PROJECT-25860059, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26461671, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26860051
[Journal Article] Protection afforded by pre- or post-treatment with 4-phenylbutyrateagainst liver injury induced by acetaminophen overdose in mice2014
- Author(s)
  Daisuke Shimizua, Yoichi Ishitsuka, Keishi Miyata, Yoshiro Tomishima, Yuki Kondo, Mitsuru Irikura, Takao Iwawaki, Yuichi Oike, Tetsumi Irie
- Journal Title
  
  Pharmacol. Res.
  
  Volume: 87 Pages: 26-41
- DOI
  10.1016/j.phrs.2014.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390049, KAKENHI-PROJECT-25461114, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
[Journal Article] The secreted protein ANGPTL2 promotes metastasis of osteosarcoma cells through integrin alpha5beta1, p38 MAPK, and matrix metalloproteinases.2014
- Author(s)
  Odagiri et al.
- Journal Title
  
  Science Signaling
  
  Volume: 7 Issue: 309
- DOI
  10.1126/scisignal.2004612
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22113009, KAKENHI-PROJECT-24370084, KAKENHI-PROJECT-25293050, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PROJECT-25870554, KAKENHI-PROJECT-26670107
[Journal Article] Clinical features of 80 cases of tinea faciei treated at a rural clinic in Japan2014
- Author(s)
  Noguchi H, Jinnin M, Miyata K, Hiruma M, Ihn H.
- Journal Title
  
  Drug Discoveries & Therapeutics
  
  Volume: 8 Issue: 6 Pages: 245-248
- DOI
  10.5582/ddt.2014.01049
- NAID
  130005054795
- ISSN
  1881-7831, 1881-784X
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461114
[Journal Article] Tissue Inhibitor of Metalloproteinase-3 Knockout Mice Exhibit Enhanced Energy Expenditure through Thermogenesis2014
- Author(s)
  Hanaoka Y, Yasuda O, Soejima H, Miyata K, Yamamoto E, Izumiya Y, Maeda N, Ohishi M, Rakugi H, Oike Y, Kim-Mitsuyama S, Ogawa H
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 4 Pages: e94930-e94930
- DOI
  10.1371/journal.pone.0094930
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23590886, KAKENHI-PROJECT-24790770, KAKENHI-PROJECT-25461114, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26461364, KAKENHI-PROJECT-26670405
[Journal Article] SIRT7 controls hepatic lipid metabolism by regulating the ubiquitin-proteasome pathway.2014
- Author(s)
  Yoshizawa T, Karim Md. F, Sato Y, Senokuchi T, Miyata K, Fukuda T, Go C, Tasaki M, Uchimura K, Kadomatsu T, Tian Z, Smolka C, Sawa T, Kakeya M, Tomizawa K, Ando Y, Araki E, Akaike T, Braun T, Oike Y, Bober E, Yamagata K.
- Journal Title
  
  Cell Metab.
  
  Volume: 9 Issue: 4 Pages: 712-721
- DOI
  10.1016/j.cmet.2014.03.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-11F01105, KAKENHI-ORGANIZER-20117001, KAKENHI-PLANNED-20117005, KAKENHI-PROJECT-21220010, KAKENHI-PROJECT-24390082, KAKENHI-PROJECT-24790557, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-25293212, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461361, KAKENHI-PROJECT-25870543, KAKENHI-PLANNED-26111008, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670207, KAKENHI-PROJECT-26670405, KAKENHI-PROJECT-26860697, KAKENHI-PROJECT-26861112
[Journal Article] Diverse roles of ANGPTL2 in physiology and pathophysiology.2014
- Author(s)
  Kadomatsu T, Endo M, Miyata K, Oike Y.
- Journal Title
  
  Trends Endocrinol Metab.
  
  Volume: 25(5) Issue: 5 Pages: 245-54
- DOI
  10.1016/j.tem.2014.03.012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25870543, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
[Journal Article] The effects of seijo-bofu-to, a traditional Japanese herbal medicine containing furanocoumarin derivatives, on the drug-metabolizing enzyme activities in healthy male volunteers.2014
- Author(s)
  Saruwatari J, Takashima A, Yoshida K, Soraoka H, Ding TB, Uchiyashiki Y, Tsuda Y, Imamura M, Oniki K, Miyata K, Nakagawa K.
- Journal Title
  
  Basic Clin Pharmacol Toxicol
  
  Volume: - Issue: 4 Pages: 360-5
- DOI
  10.1111/bcpt.12224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23510348, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25860117
[Journal Article] Serum ANGPTL2 levels reflect clinical features of breast cancer patients: implications for the pathogenesis of breast cancer metastasis.2014
- Author(s)
  Endo M, Yamamoto Y, Nakano M, Masuda T, Odagiri H, Horiguchi H, Miyata K, Kadomatsu T, Motokawa I, Okada S, Iwase H, Oike Y.
- Journal Title
  
  The International Journal of Biological Markers
  
  Volume: 印刷中 Issue: 3 Pages: 0-0
- DOI
  10.5301/jbm.5000080
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24791383, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26670405
[Journal Article] Role of endothelial cell-derived angptl2 in vascular inflammation leading to endothelial dysfunction and atherosclerosis progression.2014
- Author(s)
  Horio E, Kadomatsu T, Miyata K, Arai Y, Hosokawa K, Doi Y, et al.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 34 Issue: 4 Pages: 790-800
- DOI
  10.1161/atvbaha.113.303116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23617024, KAKENHI-PROJECT-24590797, KAKENHI-PROJECT-24590898, KAKENHI-PROJECT-24689041, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25461192, KAKENHI-PROJECT-25670453, KAKENHI-PROJECT-25870543, KAKENHI-PROJECT-25870553, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-26290035, KAKENHI-PROJECT-26293190, KAKENHI-PROJECT-26640069, KAKENHI-PROJECT-26670405
[Journal Article] A molecular clock regulates angiopoietin-like protein 2 expression.2013
- Author(s)
  Kadomatsu T et al
- Journal Title
  
  PloS One
  
  Volume: 8 Issue: 2 Pages: e57921-e57921
- DOI
  10.1371/journal.pone.0057921
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24241018, KAKENHI-PROJECT-24591060, KAKENHI-PROJECT-25461114
[Journal Article] Perivascular adipose tissue-secreted angiopoietin-like protein2 (Angptl2) accelerates neointimal hyperplasia after endovascular injury.2013
- Author(s)
  Tian Z, Miyata K, Tazume H, Sakauguchi H, Kadomatsu T, Horio E, Takahashi O, Komohara Y, Araki K, Hirata Y, Tabata M, Takanashi S, Takeya M, Hao H, Shimabukuro M, Sata M, Kawasuji M, Oike Y.
- Journal Title
  
  J Mol Cell Cardiol
  
  Volume: 57 Pages: 1-12
- DOI
  10.1016/j.yjmcc.2013.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390159, KAKENHI-PROJECT-23310135, KAKENHI-PROJECT-23591314, KAKENHI-PUBLICLY-24115712, KAKENHI-PROJECT-24659392, KAKENHI-PROJECT-25461114, KAKENHI-PROJECT-25670390
[Journal Article] Treatment of onychomycosis using a 1064nm Nd:YAG laser.2013
- Author(s)
  Noguchi H, Miyata K, Sugita T, Hiruma M, Hiruma M.
- Journal Title
  
  Med Mycol J.
  
  Volume: 54 Pages: 333-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461114
[Journal Article] The angiotensin II AT1 receptor-associated protein Arap1 is involved in sepsis-induced hypotension.2013
- Author(s)
  Mederle K, Schweda F, Kattler V, Doblinger E, Miyata K, Höcherl K, Oike Y, Castrop H.
- Journal Title
  
  Crit Care.
  
  Volume: 17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461114
[Journal Article] Angiopoietin-like protein 2 is a potent hemangiogenic and lymphangiogenic factor in corneal inflammation.2013
- Author(s)
  Toyono T, Usui T, Yokoo S, Kimakura M, Nakagawa S, Yamagami S, Miyata K, Oike Y, Amano S.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 54 Issue: 6 Pages: 4278-85
- DOI
  10.1167/iovs.12-11497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461114
[Journal Article] アンジオポエチン様因子2012
- Author(s)
  宮田敬士, 尾池雄一
- Journal Title
  
  Vascular Medicine
  
  Volume: 8巻 Pages: 61-66
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] アンジオポエチン様因子2012
- Author(s)
  宮田敬士
- Journal Title
  
  Vascular Medicine
  
  Volume: 8 Pages: 61-66
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Genetic variants at the 9p21 locus contribute to atherosclerosis through modulation of ANRIL and CDKN2A/B2012
- Author(s)
  Congrains A, Kamide K, Oguro R, Yasuda O, Miyata K, Yamamoto E, Kawai T, Kusunoki H, Yamamoto H, Takeya Y, Yamamoto K, Onishi M, Sugimoto K, Katsuya T, Awata N, Ikebe K, Gondo Y, Oike Y, Ohishi M, Rakugi H.
- Journal Title
  
  Atherosclerosis
  
  Volume: 220(2) Pages: 449-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Macrophage-derived angiopoietin-like protein 2 accelerates development of abdominal aortic aneurysm2012
- Author(s)
  Tazume H, Miyata K, Tian Z, Endo M, Horiguchi H, Takahashi O, Horio E, Tsukano H, Kadomatsu T, Nakashima Y, Kunitomo R, Kaneko Y, Moriyama S, Sakaguchi H, Okamoto K, Hara M, Yoshinaga T, Yoshimura K, Aoki H, Araki K, Hao H, Kawasuji M, Oike Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32(6) Pages: 1400-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Synthesis and Biological Evaluation of Derivatives of 2-{2-Fluoro-4-[(2-oxocyclopentyl) methyl] phenyl} propanoic Acid : Nonsteroidal Anti-Inflammatory Drugs with Low Gastric Ulcerogenic Activity2012
- Author(s)
  Yamakawa N, Suemasu S, Okamoto Y, Tanaka KI, Ishihara T, Asano T, Miyata K, Otsuka M, Mizushima T.
- Journal Title
  
  J Med Chem
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Tumor cell-derived angiopoietin-like protein ANGPTL2 is a critical driver of metastasis2012
- Author(s)
  Endo M, Nakano M, Kadomatsu T, Fukuhara S, Kuroda H, Mikami S, Hato T, Aoi J, Horiguchi H, Miyata K, Odagiri H, Masuda T, Harada M, Horio H, Hishima T, Nomori H, Ito T, Yamamoto Y, Minami T, Okada S, Takahashi T, Mochizuki N, Iwase H, Oike Y.
- Journal Title
  
  Cancer Res
  
  Volume: 72(7) Pages: 1784-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Targeted overexpression of Angptl6/angiopoietin-related growth factor in the skin promotes angiogenesis and lymphatic vessel enlargement in response to ultraviolet B2012
- Author(s)
  Okazaki H, Hirakawa S, Shudou M, Nakaoka Y, Shirakata Y, Miyata K, Oike Y, Hashimoto K, Sayama K.
- Journal Title
  
  J Dermatol
  
  Volume: 39(4) Pages: 366-74
- NAID
  10031184909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] The role of angiopoietin-like protein 2 in pathogenesis of dermatomyositis2012
- Author(s)
  Ogata A, Endo M, Aoi J, Takahashi O, Kadomatsu T, Miyata K, Tian Z, Jinnin M, Fukushima S, Ihn H, Oike Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 418(3) Pages: 494-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Angiopoietin関連因子2011
- Author(s)
  宮田敬士
- Journal Title
  
  心臓
  
  Volume: 43 Pages: 610-614
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Angiopoietin-like protein 2 is an important facilitator of inflammatory carcinogenesis and metastasis2011
- Author(s)
  Aoi J, Endo M, Kadomatsu T, Miyata K, Nakano M, Horiguchi H, Ogata A, Odagiri H, Yano M, Araki K, Jinnin M, Ito T, Hirakawa S, Ihn H, Oike Y.
- Journal Title
  
  Cancer Res
  
  Volume: 71(24) Pages: 7502-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Angptlファミリーとメタボリックシンドローム2011
- Author(s)
  宮田敬士, 尾池雄一
- Journal Title
  
  Annual Review糖尿病・代謝・内分泌2011
  
  Pages: 19-207
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Angptlファミリー2011
- Author(s)
  宮田敬士, 尾池雄一
- Journal Title
  
  日本臨牀
  
  Volume: 69巻(増刊) Pages: 319-324
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Synthesis and biological evaluation of loxoprofen derivatives2011
- Author(s)
  Yamakawa N, Suemasu S, Matoyama M, Tanaka K, Katsu T, Miyata K, Okamoto Y, Otsuka M, Mizushima T.
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 19(11) Pages: 3299-311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Nifedipine increases energy expenditure by increasing PGC-1α expression in skeletal muscle2011
- Author(s)
  Tian Z, Miyata K, Tabata M, Yano M, Tazume H, Aoi J, Takahashi O, Araki K, Kawasuji M, Oike Y.
- Journal Title
  
  Hypertens Res
  
  Volume: 34(11) Pages: 1221-7
- NAID
  10030277511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Nifedipine Increases Energy Expenditure by Increasing PGC-1α Expression in Skeletal Muscle2011
- Author(s)
  Tian Z, Miyata K, et al
- Journal Title
  
  Hypertension Research
  
  Volume: 34 Issue: 11 Pages: 1221-1227
- DOI
  10.1038/hr.2011.129
- NAID
  10030277511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111, KAKENHI-PROJECT-23310135
[Journal Article] Angipoietin関連因子2011
- Author(s)
  宮田敬士, 尾池雄一
- Journal Title
  
  心臓
  
  Volume: 43巻 Pages: 610-614
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Angptlファミリー2011
- Author(s)
  宮田敬士
- Journal Title
  
  日本臨牀(増刊)
  
  Volume: 69 Pages: 319-324
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Angptlファミリーとメタボリックシンドローム2011
- Author(s)
  宮田敬士
- Journal Title
  
  Annual Review糖尿病・代謝・内分泌2011
  
  Pages: 199-207
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] 病態におけるアンジオポエチン様因子ファミリーの役割2010
- Author(s)
  宮田敬士, 尾池雄一
- Journal Title
  
  実験医学
  
  Volume: 28巻(増刊) Pages: 1693-1697
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Macrophage-derived AIM is endocytosed into adipocytes and decreases lipid droplets via inhibition of fatty acid synthase activity2010
- Author(s)
  Kurokawa J, Arai S, Nakashima K, Nagano H, Nishijima A, Miyata K, Ose R, Mori M, Kubota N, Kadowaki T, Oike Y, Koga H, Febbraio M, Iwanaga T, Miyazaki T.
- Journal Title
  
  Cell Metab
  
  Volume: 11(6) Pages: 479-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Increased E4 activity in mice leads to ubiquitin-containing aggregates and degeneration of hypothalamic neurons resulting in obesity2010
- Author(s)
  Susaki E, Kaneko-Oshikawa C, Miyata K, Tabata M, Yamada T, Oike Y, Katagiri H, Nakayama KI.
- Journal Title
  
  J Biol Chem
  
  Volume: 285(20) Pages: 15538-47
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] The endoplasmic reticulum stress-C/EBP homologous protein pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques2010
- Author(s)
  Tsukano H, Gotoh T, Endo M, Miyata K, Tazume H, Kadomatsu T, Yano M, Iwawaki T, Kohno K, Araki K, Mizuta H, Oike Y.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 30(10) Pages: 1925-32
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] 病態におけるアンジオポエチン様因子ファミリーの役割2010
- Author(s)
  宮田敬士
- Journal Title
  
  実験医学(増刊)
  
  Volume: 28 Pages: 1693-1697
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Synoviocyte-derived angiopoietin-like protein 2 contributes to synovial chronic inflammation in rheumatoid arthritis2010
- Author(s)
  Okada T, Tsukano H, Endo M, Tabata M, Miyata K, Kadomatsu T, Miyashita K, Semba K, Nakamura E, Tsukano M, Mizuta H, Oike Y.
- Journal Title
  
  Am J Pathol
  
  Volume: 176(5) Pages: 2309-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790111
[Journal Article] Elevated mature macrophage expression of human ABHD2 gene in vulnerable plaque.2008
- Author(s)
  Keishi miyata, et. al.
- Journal Title
  
  Biochem Biophys Res Commun. 365(2)
  
  Pages: 207-213
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790504
[Presentation] The IncRNA Caren Protects Against Heart Failure by Inactivating the ATM-DNA Damage Response Pathway and Activating Mitochondrial Biogenesis2021
- Author(s)
  Sato Michio, Keishi Miyata, Yuichi Oike
- Organizer
  第85回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08560
[Presentation] Endurance exercise-induced miR221/222 promotes cardioprotection via ANGPTL2 suppression.2017
- Author(s)
  Keishi Miyata
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  石川県金沢市
- Data Source
  KAKENHI-PROJECT-16K09504
[Presentation] 病的血管リモデリングにおける血管周囲脂肪組織由来Angptl2の役割2015
- Author(s)
  宮田敬士
- Organizer
  第23回日本血管生物医学会学術集会
- Place of Presentation
  兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-25461114
[Presentation] Lack of Angiopoietin-like Protein 2 (Angptl2) Prevents Heart Failure in Murine Left Ventricular Pressure-overload Model2014
- Author(s)
  Keishi Miyata、Zhe Tian、Eiji Horio、Hirokazu Tadume、Yuichi Oike
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京・東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-25461114
[Presentation] Angiopoietin-Related Growt h Factor(AGF) Regulates Energy Meta bolism in a Manner Independent of i ts Proangiogenic Function2012
- Author(s)
  宮田敬士
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22790111
[Presentation] Angiopoietin-Related Growth Factor (AGF) Regulates Energy Metabolism in a Manner Independent of its Proangiogenic Function2012
- Author(s)
  宮田敬士
- Organizer
  第76回日本循環器学会学術集会
- Place of Presentation
  福岡県福岡市福岡国際会議場
- Year and Date
  2012-03-16
- Data Source
  KAKENHI-PROJECT-22790111
[Presentation] Angiopoietin-related Growt h Factor Has the Anti-obesity Effect through eNOS-independent Pathway2011
- Author(s)
  宮田敬士
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22790111
[Presentation] Angiopoietin-related Growth Factor Has the Anti-obesity Effect through eNOS-independent Pathway2011
- Author(s)
  宮田敬士
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川県横浜市パシフィコ横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22790111
[Presentation] Angptl6/AGF Regulates Energy Metabolism in a Manner Independent of its Proangiogenic Function2010
- Author(s)
  宮田敬士
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22790111
[Presentation] Angptl6/AGF Regulates Ener gy Metabolism in a Manner Independent of its Proangiogenic Function2010
- Author(s)
  宮田敬士
- Organizer
  第33回日本分子生物学会年会・第83回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-22790111
[Presentation] Human α/β Hydrolase Domain Containing 2 Gene is Highly Expressed in Human Coronary Artery Disease2007
- Author(s)
  宮田敬士
- Organizer
  第40回日本発生生物学会・第59回日本細胞生物学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2007-05-29
- Data Source
  KAKENHI-PROJECT-18790504

1. OIKE Yuichi (90312321)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. Kawano Takayuki (50448536)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. OHMORI Yuki (60599116)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TAZUME Hirokazu (10648273)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. TIAN Zhe (80723890)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. KAWASUJI Michio (40135067)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. HORIO Eiji

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KURATSU Junichi (20145296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Fukui Toshihiro (50445045)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 荒木喜美 (90211705)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. ENDO Motoyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. KADOMATSU Tsuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
13. MICHIUE Hiroyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. UEDA Mitsuharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. KOTANI Shunsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. SARUWATARI Junji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
17. TANAKA Kenichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. YASUDA Osamu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. YAMAMOTO Eiichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. IZUMI Yuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. ARAI Yasumichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 松井秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 村上誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 岩脇隆夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 安東由喜雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 中川和子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
27. 鬼木健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
28. 向山政志

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
29. 木村俊寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 樂木宏美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 田中廣壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 清水宣明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 吉川賢忠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 平田恭信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 佐田政隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 馬場理也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 荒木栄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 中野正啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIYATA KEISHI 宮田 敬士

MIYATA Keishi 宮田 敬士

宮田 敬士 ミヤタ ケイシ

Research Projects

Research Products

Co-Researchers

SGLT２阻害薬長期投与による心筋細胞内鉄動態・代謝の変容と心機能への影響の検討Principal Investigator

Principal Investigator

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「鉄」を標的とした心不全病態解明と新規治療戦略Principal Investigator

Principal Investigator

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Research Category

Review Section

Research Institution

Elucidation of novel molecular mechanisms of the treatment strategy for heart failure by inactivating the DNA damage responsePrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Mechanism of arteriosclerosis targeting chronic inflammation and possibility of new drug treatment

Principal Investigator

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Research Institution

The role of microRNA in molecular mechanism of heart failure developmentPrincipal Investigator

Principal Investigator

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Research Institution

The discovery of a new predictor of aortic aneurysm rupture

Principal Investigator

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Research Institution

The role of long non-cording RNA in pathological mechanism of heart failure.Principal Investigator

Principal Investigator

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The basic research for the relationship of chronic inflammation and pathogenesis of cerebral aneurysm

Principal Investigator

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The discovery of a new predictor of aortic aneurysm rupture

Principal Investigator

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Molecular and functional analysis of bioactive factor AGF in biological control systemPrincipal Investigator

Principal Investigator

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血管におけるAbhd2遺伝子の機能解析Principal Investigator

Principal Investigator

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Research Institution

[Journal Article] Tumor stroma-derived ANGPTL2 potentiates immune checkpoint inhibitor efficacy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fasudil inhibits the expression of C/EBP homologous protein to protect against liver injury in acetaminophen-overdosed mice2023

Author(s)

Journal Title

MIYATA KEISHI 宮田敬士

MIYATA Keishi 宮田敬士

宮田敬士ミヤタケイシ

[Journal Article] Hyperglycemia and Thrombocytopenia　― Combinatorially Increase the Risk of Mortality in Patients With Acute Myocardial Infarction Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation ―2021